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Psychopharmacological Analysis Of Central Muscarinic And Nicotinic Receptors, Leonard T. Meltzer

Theses and Dissertations

Arecoline and nicotine are two psychoactive cholinergic alkaloids. Arecoline is primarily a muscarinic agonist while nicotine, at low doses, is a nicotinic agonist. The experiments in this dissertation investigated two major areas: (1) the role of different factors in the development of tolerance to the behavioral effects of arecoline and nicotine, and (2) the possible mechanism and site of action of the discriminative stimulus (DS) effects of arecoline and nicotine.

The role of dispositional and physiological factors comfiared to behavioral factors in the development of tolerance to the effects of arecoline and nicotine on operant behavior was assessed in Experiments …

Investigation Of A Factor Released By Neoplastic Cells Which Produces A Chemokinetic Response In Activated Macrophages, Richard Durelle Lane

Theses and Dissertations

The increase in rate of random migration (chemokinesis) of C. parvum activated macrophages in media conditioned by Lewis Lung (LL) carcinoma cells was attributed to a trypsin sensitive, heat stable, high molecular weight factor released from the membrane of the tumor cells.

A capillary tube assay was developed to expediently monitor the chemokinetic activity of macrophages incubated in whole and fractionated media. The capillary tube assay was found to be capable of detecting both chemokinetic and chemotactic (directional movement) factors present in the test media. Statistical analysis revealed the capillary tube assay provided reproducible data both within and between experiments. …

Regulation Of Cartilage Acid Hydrolases And Their Relationship To Skeletal Growth, John Richard Hubbard

Theses and Dissertations

The in vivo regulation of several acid hydrolases by growth hormone was investigated in an attempt to lend insight into the mechanism of growth hormone action. In addition, the relationship of these enzymes to age-dependent changes in skeletal growth rate was examined. Initial studies showed that hypophysectomy reduced the activity of an unknown cartilage protease, which was assayed by digestion of gelatin-membrane substrates at pH 4.0. Treatment of hypophysectomized rats with growth hormone enhanced this activity to about normal levels. The unidentified protease activity was also shown to be higher in younger, more rapidly growing rats, than in older, less …

Comparison Of Burned Patients' Perception Of Pain With Nurses' Perception Of Patients' Pain, Merri Diane Walkenstein

Theses and Dissertations

Pain is a universal experience. Caring for people in pain is a central aspect of nursing practice. Many studies have been done to determine the physical and psychosocial mechanisms of the pain sensation, in addition to methods of relief. Very little has been done, however, dealing specifically with the pain experienced by the burned patient.

People hospitalized with thermal injuries complain most often of the intensity and long duration of their pain experience. Due to the large number of persons sustaining thermal injuries every year, it is apparent that nurses must familiarize themselves with methods of evaluation and intervention to …

Kalki, Studies In James Branch Cabell (Vol. 8, No. 1, 1980)

Kalki, Studies in James Branch Cabell

No abstract provided.

Efficacy Of Salinomycin On Infections Of Plasmodium Berghei In Male Icr Mice, Anthony Stephen Tokarz

Theses and Dissertations

The objective of this study was to determine whether or not salinomycin, a drug with proven effectiveness against intestinal sporozoan parasites, has any effect on the survival time of mice infected with P. berghei.

The Chronic Effects Of Estradiol Benzoate On Ventricular Myocardial Blood Flow In The Adult Female Rat, Stephen Maurice Ashe

Theses and Dissertations

Clinical and experimental data suggest that humans and some animals are protected from acute myocardial infarction by estrogen. There has been much speculation of the exact role which estrogen plays in the circulation. The mechanism of this hormonally related protection is unclear.

In the present study the chronic effects of estradiol benzoate on coronary blood flow in adult female rats were studied. Female control rats, castrates and castrates receiving estrogen for a period of 16 weeks were used. In vivo tracer microsphere studies of myocardial blood flow allowed the quantification of the effects of estrogen on coronary circulation. Results of …

A Sourcebook For The Production Of Musical Dramas And Programs In The Elementary School, Carole Elizabeth Bradley

Theses and Dissertations

The search for educational goals in music productions leads the teacher to a variety of sources for guidance: publications, workshops, and other teachers. None of these sources alone are adequate to the task. The need, then, is to bring together all of this information into one sourcebook. It is this sourcebook that the present study has endeavored to provide.

The purpose of this study has been to develop a sourcebook of practical information for the production of elementary musical dramas and programs and to provide general principles of production as a guide for music teachers. Criteria for creative environments which …

Commonwealth Times 1979-11-13

Commonwealth Times, 1969-

No abstract provided.

Commonwealth Times 1979-11-06

Commonwealth Times, 1969-

No abstract provided.

Commonwealth Times 1979-10-02

Commonwealth Times, 1969-

No abstract provided.

Commonwealth Times 1979-09-18

Commonwealth Times, 1969-

No abstract provided.

Vcu Magazine (1979-06)

VCU Magazine, 1971-1993

A publication for alumni and friends of Virginia Commonwealth University.

Commonwealth Times 1979-04-24

Commonwealth Times, 1969-

No abstract provided.

Commonwealth Times 1979-04-17

Commonwealth Times, 1969-

No abstract provided.

Commonwealth Times 1979-03-20

Commonwealth Times, 1969-

No abstract provided.

Commonwealth Times 1979-03-13

Commonwealth Times, 1969-

No abstract provided.

Reflections In Ink (1979-03)

Reflections in Ink, 1978-1994

Reflections in Ink was an alternative newspaper began through collaboration of the Black Student Alliance and the VCU student branch of the League of Black Journalists, that published from 1978 to 1993 before changing its name to The Vine.

Vcu Magazine (1979-03)

VCU Magazine, 1971-1993

A publication for alumni and friends of Virginia Commonwealth University.

Commonwealth Times 1979-02-27

Commonwealth Times, 1969-

No abstract provided.

Vcu Today (1979-02-20)

VCU Today, 1972-1988

VCU Today, the University’s first official administrative organ, began as a somewhat irregular monthly publication but moved to a bi-weekly newspaper format in the 1980s. The newspaper changed its name to VCU Voice in 1988 and ten years later it appeared under the title UniverCity News. As it neared the end of its run as a physical newspaper, the publication became simply VCU News. These four publications were essentially the same periodical published under different titles by the Office of University Relations. VCU News appeared online for the first time in 2002.

Commonwealth Times 1979-02-06

Commonwealth Times, 1969-

No abstract provided.

Human Infection From An Unidentified Erythrocyte-Associated Bacterium, Gordon L. Archer , M.D., Philip H. Coleman , D.V.M., Ph.D., Roger M. Cole , M.D., Ph.D., Richard J. Duma , M.D., Ph.D., Charles L. Johnston , Jr., M.D.

Internal Medicine Publications

Abstract

A 49-year-old splenectomized man had an infection from an unidentified, gram-positive, rodshaped bacterium that adhered to the majority of his peripheral-blood erythrocytes. On transmission electron microscopy, the bacterium was seen to be extraerythrocytic and was 0.2 μm wide by 1.0 to 1.7 μm long. It possessed a thick, granular cell wall, a trilamellar membrane external to the cell wall and prominent mesosomes. Attempts to cultivate the organism in vitro or to duplicate the patient's disease in splenectomized animals were unsuccessful. The patient's response suggested that the bacterium was susceptible to cell-wall-active antibiotics and to chloramphenicol but not to tetracycline. …

Virginia Commonwealth University Medical College Of Virginia Bulletin [1979], Virginia Commonwealth University

VCU Bulletins

MCV bulletin for Virginia Commonwealth University includes information on academic regulations, degree requirements, course offerings, faculty, academic calendar, and tuition and expenses for professional programs on the MCV campus.

Chronic Obstructive Pulmonary Disease: Outpatient Management, James P. Baker

MCV/Q, Medical College of Virginia Quarterly

Chronic obstructive pulmonary disease has become one of the more common problems which face physicians both in inpatient and outpatient settings. The incidence of the disease and increase in mortality have been documented in a number of studies as have other lung diseases, indicating a general rise in pulmonary disorders over the past several decades. Two types of disease are classified under the heading of chronic pulmonary disease: chronic bronchitis and pulmonary emphysema. Chronic bronchitis is defined as a clinical syndrome of cough and sputum production for three consecutive months over two consecutive years, and pulmonary emphysema is defined as …

Commonwealth (1979)

Commonwealth (VCU, 1979-1980)

The yearbook of Virginia Commonwealth University.

Mcv/Q, Medical College Of Virginia Quarterly, Vol. 15 No. 3

MCV/Q, Medical College of Virginia Quarterly

No abstract provided.

Research In Action (1979-01)

Research in Action, 1975-1987

A publication devoted to describing the scholarly and creative activities of Virginia Commonwealth University.

[Review Of] Gretchen M. Bataille, David M. Gradwohl, And Charles L. P. Silet (Eds.), The Worlds Between Two Rivers: Perspectives On American Indians In Iowa, William Bedford Clark

Explorations in Ethnic Studies

The presentation of symposia papers in book form poses several editorial problems, the chief of which is maintaining a unity of focus between the various offerings. With one or two notable exceptions, the papers in this collection treat aspects of the Native-American experience within the boundaries of the present state of Iowa, but, unfortunately, that rubric is too broad to provide an organizing principle definite enough to hold the book together. The result is something of a mixed bag. Although each of the papers is presented as a “chapter” and some attempt at cross-reference between individual papers is made, it …

New Skin: Ellison, Jung, And The Unconscious, Dona Hoilman

Explorations in Ethnic Studies

Marshall McLuhan contends that the electric media, television in particular, have given Americans the means of instant, total awareness both of themselves, especially of their unconscious or subliminal states, and of others, who may differ in skin color or points of view but with whom total social involvement is now not only desirable, but absolutely necessary in the ontological sense of the word. However, though television may have made us more conscious of our unconscious and more aware of the dynamic relationship between other individuals’ well-being and our own, the mutual feeding and forming and mutilating of one another’s psyches …