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The Effects Of Streptozotocin-Induced Diabetes On Responses To Opiates And Other Centrally-Acting Pharmacologic Agents, Glenn Stuart Simon

Theses and Dissertations

Diabetes mellitus affects millions of people. Although diabetics can lead relatively normal lives, all treatments for the disease are symptomatic and not curative. The purpose of this investigation was to determine whether the sensitivity to opiates and other selected centrally-acting drugs in animals is altered by streptozotocin (STZ)-induced diabetes. A second objective was to determine which aspect of the diabetic syndrome primarily was responsible for the altered sensitivity. Other experiments were performed in an attempt to elucidate the mechanism whereby this altered sensitivity occurred.

STZ-induced diabetes or dextrose-induced transient hyperglycemia did not have a significant effect on the duration of …

The Measurement Of Anger In Children: A Multi-Modal Approach, Edward Shirrell Eastman Jr.

Theses and Dissertations

The objective of this study was to utilize self-report, peer-report and teacher-report techniques in measuring (reporting) anger in children; and to determine the intercorrelation between these three approaches in order to determine their relationship to one another and in turn, to assess these reporting tools. Subjects were 38 male and female emotionally disturbed children from the Virginia Treatment Center for Children, a short-term residential psychiatric facility in Richmond, Virginia. There were 28 boys and 10 girls, with a mean age of approximately 11 years.

Each student was given the Children's Inventory of Anger (CIA) and the Peer-Report of Anger (PR). …

Antiviral Activity Of Peritoneal Exudate Cells Of Mice Against Infection With Herpes Simplex Virus Type 2, Margaret Byrd Mcgeorge

Theses and Dissertations

Within the past decade, there has been increasing evidence which suggests that herpes simplex virus type two (HSV-2) is associated with cervical carcinoma. Because cancer of the cervix ranks as the second most common malignant disease of women, with 35 thousand new cases and 10,000 deaths per year, further investigation is warranted to determine if there is a causal relationship (Goldberg, 1976). Currently, most of the evidence which correlates HSV-2 with cancer of the cervix has been, for the most part, indirect: (i) there is an increased incidence of cervical anaplasia in women with cytologically detectable genital herpes infection, (ii) …

Virginia Dental Journal (Vol. 56, No. 1, 1979)

Virginia Dental Journal

No abstract provided.

A Study To Compare The Strength Changes After Training The Abductor Digiti Minimi In Young Adults And In Geriatric Adults, Timothy Lee Kauffman

Theses and Dissertations

A paucity of research exists in the strength training and aging literature. Hettinger (1958) reported that strength declined with age and that older persons gained less with strength training than younger persons. This study altered Hettinger's design by using a different muscle and a different strengthening routine. The purpose of this study was to compare the effects of isometric strength training of the non-dominant left abductor digiti minimi muscles of young subjects and old subjects. The ten young female subjects, mean age 22.6 years, were all nursing students. The ten older female subjects, mean age 69.2 years, did not constitute …

A Question Of Influence: William Cowper Brann And Henry Louis Mencken, Dale Owen Bishop

Theses and Dissertations

A major critic of H. L. Mencken and a co-worker of his on the Baltimore Sun have both theorized that Mencken was influenced by a little-remembered Texas iconoclast who was assassinated in 1898, William Cowper Brann. Investigation revealed that Brann and Mencken agreed on many topics such as Prohibition, politics and religion among others. Mencken's early style compares well with Brann's, and they shared many techniques and preferences for particular words standard in the debunker's vocabulary. Research revealed that Mencken even published an article in 1900, at the age of twenty, in the magazine that had formerly been published by …

Oncogenic Transformation By Herpes Simplex Virus, James Christian Burns

Theses and Dissertations

Many lines of evidence exist associating herpes simplex virus (HSV) with the development of carcinoma. Data from human studies includes seroepidemiologic studies of carcinoma patients and the localization of viral markers in human cancers. Experimental studies include in vitro transformation of cultured cells and viral induced alterations of host DNA. Much of this evidence is anecdotal or associative in nature and does not prove a cause and effect. The purpose of this research was to investigate the oncogenic potential of HSV type 2 (HSV-2) in vivo and in vitro.

An in vivo mouse model for lib carcinogenesis was designed to …

Characterization Of The Bursicon-Mediated Pathway For Membrane Permeability Enhancement In The American Cockroach, Periplaneta Americana, David Alan Compton

Theses and Dissertations

The presence of an adenyl cyclase system within the haemocyte of Periplaneta americana has been confirmed by previous investigations, with corresponding experiments using dibutyryl cyclic AMP to show enhancement of 14c-tyrosine uptake into the cuticle linked to stimulation of the sclerotization process.

In the present studies, American cockroaches held at depressed temperatures were treated with bursicon, revealing an increase in haemocyte cyclic AMP concentrations. The levels declined with progression of time, probably resulting from enzymatic hydrolysis.

When animals which had been held at room temperature were treated with bursicon, the levels of haemocyte cyclic AMP were lowered, with a declination …

The Responsiveness Of Murine Tumors To Maleic Vinyl Ether, Paal Christian Klykken

Theses and Dissertations

Studies were undertaken to characterize the immune status of mice bearing the Lewis lung carcinoma (LLC) and to maximize the cure rate of LLC and Madison l09 carcinoma (Ml09) bearing mice by employing the immunomodulator maleic vinyl ether (MVE) in combination with surgery or radiotherapy.

The pattern of immunodeficiency in mice bearing the LLC appeared to be in contrast to most studies. LLC mice with a minimal tumor burden were found to have a diminished ability to phagocytize sheep erythorcytes (SRBC) or elicit an antibody response to the same antigen. Vascular clearance and phagocytic uptake of ⁵¹Cr-labeled SRBC into …

Intravenous Infection Of Mice With Naegleria Fowleri, Richard G. May

Theses and Dissertations

Primary amebic meningoencephalitis is a fatal disease of man caused by the free-living ameboflagelate Naegleria fowleri. In general, the victims have been active, healthy, young adults with a recent history of swimming or other fresh water-related activity. Infection with N. fowleri is apparently by way of nasal introduction of amebae-containing water. After nasal installation, electron microscopic and histopathologic studies with experimental animals reveal that amebae reside in the olfactory mucosa and then invade and migrate through the submucosal structures into the nerve plexuses. Amebae pass through pores of the cribiform plate and into the subarachnoid space. Subsequently, amebae invade the …

To Clothe A Fool : A Study Of The Apparel Appropriate For The European Court Fool 1300 - 1700, Virginia Lee Futcher

Theses and Dissertations

In order to design a costume for a period show, a costumer must unify the personality of the character in the appropriate historical style with the director's concept for the production. My study endeavors to aid the costumer in search of the historical clothes of the Medieval and Renaissance court Fool. Lack of time to do extensive research often imposes limitations on a designer's creativity. Through extensive research. into Medieval and Renaissance art, with the aid of Robert Armin's jest book, and descriptions of the household accounts of the period, I have compiled a document that will save a harried …

Commonwealth Times 1978-12-12

Commonwealth Times, 1969-

No abstract provided.

Commonwealth Times 1978-11-14

Commonwealth Times, 1969-

No abstract provided.

Vcu Today (1978-10-24)

VCU Today, 1972-1988

VCU Today, the University’s first official administrative organ, began as a somewhat irregular monthly publication but moved to a bi-weekly newspaper format in the 1980s. The newspaper changed its name to VCU Voice in 1988 and ten years later it appeared under the title UniverCity News. As it neared the end of its run as a physical newspaper, the publication became simply VCU News. These four publications were essentially the same periodical published under different titles by the Office of University Relations. VCU News appeared online for the first time in 2002.

Vcu Today (1978-10-10)

VCU Today, 1972-1988

VCU Today, the University’s first official administrative organ, began as a somewhat irregular monthly publication but moved to a bi-weekly newspaper format in the 1980s. The newspaper changed its name to VCU Voice in 1988 and ten years later it appeared under the title UniverCity News. As it neared the end of its run as a physical newspaper, the publication became simply VCU News. These four publications were essentially the same periodical published under different titles by the Office of University Relations. VCU News appeared online for the first time in 2002.

Commonwealth Times 1978-10-10

Commonwealth Times, 1969-

No abstract provided.

Reflections In Ink (1978-09)

Reflections in Ink, 1978-1994

Reflections in Ink was an alternative newspaper began through collaboration of the Black Student Alliance and the VCU student branch of the League of Black Journalists, that published from 1978 to 1993 before changing its name to The Vine.

Commonwealth Times 1978-06-13 Summer 1978

Commonwealth Times, 1969-

No abstract provided.

[1978-05-18] Minutes Of A Regular Meeting Of The Board Of Visitors Of Virginia Commonwealth University May 18, 1978., Virginia Commonwealth University. Board Of Visitors

VCU Board of Visitors Minutes

Official minutes of the VCU Board of Visitors and its Executive Committee.

Vcu Today (1978-04-25)

VCU Today, 1972-1988

VCU Today, the University’s first official administrative organ, began as a somewhat irregular monthly publication but moved to a bi-weekly newspaper format in the 1980s. The newspaper changed its name to VCU Voice in 1988 and ten years later it appeared under the title UniverCity News. As it neared the end of its run as a physical newspaper, the publication became simply VCU News. These four publications were essentially the same periodical published under different titles by the Office of University Relations. VCU News appeared online for the first time in 2002.

Commonwealth Times 1978-04-18

Commonwealth Times, 1969-

No abstract provided.

Vcu Today (1978-04-11)

VCU Today, 1972-1988

VCU Today, the University’s first official administrative organ, began as a somewhat irregular monthly publication but moved to a bi-weekly newspaper format in the 1980s. The newspaper changed its name to VCU Voice in 1988 and ten years later it appeared under the title UniverCity News. As it neared the end of its run as a physical newspaper, the publication became simply VCU News. These four publications were essentially the same periodical published under different titles by the Office of University Relations. VCU News appeared online for the first time in 2002.

Commonwealth Times 1978-04-04

Commonwealth Times, 1969-

No abstract provided.

Vcu Today (1978-01-24)

VCU Today, 1972-1988

VCU Today, the University’s first official administrative organ, began as a somewhat irregular monthly publication but moved to a bi-weekly newspaper format in the 1980s. The newspaper changed its name to VCU Voice in 1988 and ten years later it appeared under the title UniverCity News. As it neared the end of its run as a physical newspaper, the publication became simply VCU News. These four publications were essentially the same periodical published under different titles by the Office of University Relations. VCU News appeared online for the first time in 2002.

Commonwealth Times 1978-01-17

Commonwealth Times, 1969-

No abstract provided.

Mcv/Q, Medical College Of Virginia Quarterly, Vol. 14 No. 1

MCV/Q, Medical College of Virginia Quarterly

No abstract provided.

Pyelonephritis, William F. Falls Jr.

MCV/Q, Medical College of Virginia Quarterly

The purpose of this paper is to review current thinking about pyelonephritis. Pyelonephritis may be defined as a "bacterial infection of the kidney which affects the parenchyma, the pelvis, and the calyces. It occurs in two forms, acute and chronic."

Patterns Of Prehistoric Epidemiology And Human Paleopathology, Mahmoud Y. El-Najjar

MCV/Q, Medical College of Virginia Quarterly

Human paleopathologists are interested in the visible marks of diagnosable disease that reflect various aspects of human biocultural interaction. Whether infectious, nutritional, or a combination of both, pathological characteristics in the dry bone provide some insight into the health of past human populations. Paleoepidemiology and human paleopathology are important parts of ecology in that they deal directly with a major aspect of man's relationship to his environment. The significance of this relationship has, to a large extent, been neglected by human skeletal biologists. The purpose of this study is to examine one of the most important aspects of human biocultural …

Mcv/Q, Medical College Of Virginia Quarterly, Vol. 14 No. 3

MCV/Q, Medical College of Virginia Quarterly

No abstract provided.

Glomerulonephritis, William F. Falls Jr.

MCV/Q, Medical College of Virginia Quarterly

In this paper the histologic picture of the most common disorders usually classified under the heading of glomerulonephritis will be reviewed, and the subject of angiitis will be briefly addressed. A special effort will be made to relate renal biopsy findings to the immunologically mediated pathogenetic process which is thought to be operative in each case. Where it seems appropriate, a few comments will also be made on clinical and pathological correlations. The specific entities to be covered include: diffuse proliferative glomerulonephritis; focal proliferative glomerulonephritis; membranous glomerulonephritis; antibasement membrane antibody disease; rapidly progressive glomerulonephritis (crescentic disease); membranoproliferative glomerulonephritis; lipoid nephrosis …