Digital Commons Network^™

America's Sailor Moon, Cici Eltermann

Jurgen Banned Art Comics Contest

Honorable mention in the Fall 2023 Jurgen Banned Art Comics Contest.

A wry account of how the relationship of two queer characters in the Japanese anime “Sailor Moon” was changed for the English-language dub.

Ink (2023)

Ink, 2008-

The student-run features magazine covering the fashion, art, music and culture worlds at VCU and in Richmond. Published annually in print and updated regularly online.

Commonwealth Times 2023-09-06

Commonwealth Times, 1969-

No abstract provided.

Chemoattractant Distribution In Complex Geometry Impacts The Trajectory Of Clustered Cell Migration, Naghmeh Akhavan

Biology and Medicine Through Mathematics Conference

No abstract provided.

Commonwealth Times 2023-02-01

Commonwealth Times, 1969-

No abstract provided.

Dataset: Combined Coded Assessments Of Sts Science Cafes (2017-2019), Karen A. Rader, Cynthia Gibbs

STS in Science Cafes

No abstract provided.

Chesterfield Fire And Ems Mobile Integrated Healthcare: Background And A Case Study, David Bigelow

Case Studies from Age in Action

Learning Objectives

• Explain the history of Mobile Integrated Healthcare.
• Understand the importance of reducing hospital readmissions.
• Learn how MIH partners with Adult Protective Services and others for the benefit of their patients.

Virginia Commonwealth University Courses [2023], Virginia Commonwealth University

VCU Bulletins

Listing of courses for the 2023-2024 year.

Tales From The Virtual Curation Lab, Issue 01, Maggie Colangelo, Bernard Means

Virtual Curation Lab's Comic Publications

"Tales from the Virtual Curation Lab brings you fascinating graphic narratives inspired by artifacts, fossils, historic objects—and even one person—3D scanned by VCU’s Virtual Curation Laboratory. Read about an Ice Age camel that had its face ripped of by a bear, the world’s oldest ham, a vampire’s skull, and more!”--back cover

Away From Home: William Gifford Palgrave's Letters From India, 1847-1848, David E. Latane

English Publications

William Gifford Palgrave (1826-1888) became one of the great Victorian travelers, immortalized in a poem by Alfred Tennyson, “To Ulysses,” in 1888. The letters transcribed here are the record of his first voyage outward in 1847 as an Ensign in the 8th Bombay regiment of native infantry, just after his graduating with a First from Oxford. The letters are found in volume 5 of the Palgrave papers (British Library Add. MS 45738). The first letter is to his mother, dated 28 January 1847 from “Off Cape Mondego” in Portugal, and it describes life on board an outbound steamer. The last …

The Mystery Of The Missing Megafauna, Maggie Colangelo, Bernard Means

Virtual Curation Lab's Comic Publications

The creative team behind Founding Monsters and Founding Monsters Tales have created a new comic that takes a more scientific and less historic approach to the giant mammals that once roamed North America. The Mystery of the Missing Megafauna explores how changing climate impacted biodiversity and megafauna populations in North America at the end of the last Ice Age. Particular attention is placed on the extinction of mastodons, mammoths, giant ground sloths and other megafauna whose fossils are found at Saltville in southwestern Virginia. This comic draws a connection to contemporary climate change and the major extinctions happening today. The …

Culturally Responsive One-Shots Flowing From Institutional Data, Hope Y. Kelly Phd

VCU Libraries Faculty and Staff Presentations

Explore how aggregated institutional data can inform culturally responsive instructional design and delivery through a case from a public, urban, minority-serving institution.

Virginia Commonwealth University’s Office of Strategic Enrollment Management and Student Success annually shares a “Freshman Profile” that helps instructors gain insight into the student population we see in our library instruction sessions. This descriptive data paints a general picture of our first year students while maintaining individual privacy. This information is used to design and develop culturally responsive one-shot instruction that is in dialogue with race, gender, economics, family educational experience, academic preparedness and motivation, and social factors. …

A Methodology Of Paradoxes: Investigating Authenticity In The Representation Of Queerness On The Contemporary Stage, Kendall C. Walker

Theses and Dissertations

In my experience as a queer theatre practitioner, performer, and student, I have always had questions of ownership and authenticity when it comes to LGBTQIA+ narratives on the contemporary theatre stage. The question of: “Who is allowed to tell what story?” and the many complex ideas that this leads to, is what has inspired this thesis and my own pedagogy of intersectionality and inclusivity.

The purpose of this thesis is to investigate the relationship between authenticity and queerness on the contemporary stage in order to develop a methodology for how all theatre practitioners—no matter their identity—can effectively tell queer-identifying stories …

Bet Inhibition As A Strategy For Enhancing The Response To Estrogen Antagonism/Cdk4-6 Inhibition In Er Positive Breast Cancer, Ahmed M. Elshazly

Theses and Dissertations

Breast cancer is the most commonly occurring malignancy in females, accounting for the second most common cause of cancer-related deaths. ER+ breast cancer constitutes approximately 70% of all breast cancer cases. The standard care of therapy comprises endocrine antagonists together with adjuvant therapy; however, the recovery from the therapy-suppressive state is associated with further drug resistance together with increasing tumor aggressiveness and with possible metastasis. Autophagy induction has been shown to be associated with various therapeutic modalities, with different functions, including cytotoxic, cytoprotective, cytostatic as well as non-protective forms. The triggering of autophagy may be responsible for resistance development and …

An Introduction To Theatrical Scent Design As Compared To Traditional Design Areas With A Consideration For The Scientifically Notated Physical And Emotional Effects On The Human Body As It Potentially Relates To Future Creative Endeavors: A Framework, Katherine R. Holland

Theses and Dissertations

Traditional areas of theatrical design are established to the point of having a solid foundation for current and future designers to rely on as they strive to innovate. The same cannot be said for scent. I believe that art, like science, is a sector where the imagination is used to push the boundaries of what we currently know and can do. Artists are therefore entrusted with the responsibility to continue testing those boundaries, and that is what my topic lays the foundation for when it comes to scent. With my topic, I plan to look at the practical and ethical …

Effects Of Hiv-1 Tat And Opiates On Gene Regulation Of Oligodendrocyte Lineage Cells: Identification Of Myrf As A Novel Target, Kelly M. Flounlacker

Theses and Dissertations

HIV-associated neurocognitive disorders remain pervasive even with increased efficacy/use of antiretroviral therapies. Opioid use/abuse among HIV+ individuals is documented to exacerbate deficits. White matter (WM) alterations (myelin pallor, volume/structural) detected by diffusion tensor imaging, are common observations in HIV+ individuals. Using transgenic mice expressing HIV-1 Tat, we examined effects of 2-6 weeks of Tat/morphine exposure on WM using genomic/biochemical methods. RNA sequencing of striatal tissue after 2-weeks revealed robust changes in mRNAs associated with oligodendrocyte populations/myelin integrity, including Transferrin, Ndrg1, and myelin regulatory factor (Myrf/Mrf), an oligodendrocyte-specific transcription factor involved in differentiation/maturation. Immunoblots conducted after 6-weeks exposure in …

Quantifying Insect Emergence In Tidal Freshwaters And The Importance Of Aquatic Prey In Wetland-Dependent Songbird Diet, Samantha L. Rogers

Theses and Dissertations

Insectivorous birds and their arthropod prey are experiencing widespread population declines, driven largely by anthropogenic disturbance and climate change. For wetland-dependent insectivores that consume a mixture of terrestrial and aquatic insects, understanding the availability, consumption, and nutritional qualities of aquatic diet subsidies is important for conservation. I use prothonotary warblers (Protonotaria citrea) as a model species throughout this work, because their breeding season aligns with aquatic insect emergence and they include aquatic insects when provisioning nestlings. In the first chapter, I estimate aquatic insect emergence from tidal freshwaters, which are understudied compared to nontidal systems. Using continuous field …

Modulation Of Opioid-Induced Respiratory Depression By Stimulants And Their Associated Monoaminergic Receptor Mechanisms In Mice Using Whole Body Plethysmography, Harrison J. Elder

Theses and Dissertations

Opioid overdose and associated deaths involving opioid-induced respiratory depression (OIRD) began to accelerate beginning in 2015 with the emergence of illicitly manufactured fentanyl and its analogs and currently represents one of the most significant public health challenges in the United States. The increases in overdose deaths have occurred despite the increased availability of the opioid overdose reversal agent, naloxone, to first responders and the public. This new phase of the opioid epidemic has been paralleled by substantial growth in the co-use of opioids with stimulants, particularly methamphetamine. The objective of this dissertation is to ascertain whether fentanyl is particularly resistant …

A Six-Month Comparison Of Orthodontic Pain Associated With Fixed Edgewise Appliances And Clear Aligners, Victor Chan

Theses and Dissertations

Title: A Six-Month Comparison of Orthodontic Pain Associated with Clear Aligners and Fixed Edgewise Appliances

Objective: To document and compare pain perception, intensity, and analgesic use over a sixmonth period between patients treated with fixed appliances (FA) and clear aligners (CA).

Methods: A prospective, parallel, two-arm, multi-center, longitudinal cohort study was conducted with 87 adults treated with CA (n=59) or FA (n=28). Subjects were selected according to inclusion and exclusion criteria. A seven-item, digital survey was sent at three timepoints (preappointment, 2-days post-appointment, and 7-days post-appointment) at each adjustment over a six-month period. The variables measured included pain experience, pain …

Biting Range, Effie Bowen

Theses and Dissertations

Biting Range is an essayic text about dogs, process, order, and memory. Structured as a conceptual material list, the writing addresses experiential textures and tensions gleaned from observation. Writing within and against the margins, I address the performativity of the page as its own form to be agitated.

How Stromal Interactions Play A Role In The Quest For Human Papillomavirus Specific Cancer Therapeutics, Alexis-Leigh A. Fakunmoju

Theses and Dissertations

High-risk human papillomaviruses (HPV), like HPV16 and HPV18, are associated with malignant cancer growth within the oropharynx and cervix. Globally, HPV-induced cancers, including oropharyngeal and cervical cancers, contribute 5% to the overwhelming burden of all cancers. HPV is highly transmissible by sexual contact via micro abrasions to the mucosa. Once exposure occurs, the virus begins replication and creates an intimate relationship with the host’s cellular proteins. While most HPV is cleared quickly by our immune system, persistent infections, or infections in immune compromised individuals, are susceptible to transformation and tumor progression. Early detection measures like PAP smears and preventable measures …

Radiation Shielding Effectiveness Of Hafnium Diboride (Hfb2) Reinforced Epoxy Composites For Enhanced Radiation Protection And Safety, Furkan Erdogan

Theses and Dissertations

This thesis investigates the radiation shielding effectiveness of hafnium diboride (HfB2) reinforced epoxy composites, with the aim of enhancing radiation protection and safety in various applications. The study focuses on the development and characterization of HfB2-epoxy composites with varying weight percentages of HfB2 nanoparticles, as well as on the evaluation of their shielding effectiveness against gamma rays and thermal neutrons. The radiation shielding performance of the composites is assessed using gamma-ray spectroscopy and neutron counting, and the neutron attenuation efficacy is compared with that of 5% borated high-dense polyethylene. The results indicate that the HfB2-epoxy composites exhibit promising radiation shielding …

Totem Impulse, Tendai T. Mupita

Theses and Dissertations

In this reading, I explore the performative and complexities of indigenous mythologies, cosmologies, and epistemologies, through totems, folklore, architecture, and games. This paper extracts references from indigenous philosophies in thinking about form and image. These forms and images are my sculptures, my installations, and my lines.

Behind The Gate: Syrian Women In Soap Operas - Perception Vs. Reality, Tasnim J. Rahimah

Theses and Dissertations

Syria has witnessed what is known as al-fawra al-drameya, an eruption of drama since 2000. Every year, especially during Ramadan, dozens of Syrian soap operas are aired across the Arab world and beyond, depicting Syrians’ historical struggles as they fought for liberation from the French mandate at the beginning of the 20th century. Although women of those days were a vital part of that liberation movement and had prominent societal roles, these historical fiction soap operas chose to portray only the demure and dismissive female figures and not mention the women who were independent, courageous, and active members of the …

Exploring Polyamorous Relationship Experiences Of Lesbian, Gay, Bisexual, And Pansexual Individuals, Jiale Man

Theses and Dissertations

Polyamory is a type of relationship under the consensual non-monogamy relationship umbrella that assumes the possibility, validity, and worthwhileness of maintaining romantic, sexual, and intimate relationships with multiple people simultaneously. In Western society, the prevalence and domination of mononormativity have led to the marginalization of relationships alternative to monogamy (i.e., polyamory). As a result, individuals in polyamorous relationships continue to experience bias, stigma, and discrimination at varying levels. With a rise in public interest in CNM in the past two decades, scientists and researchers have slowly started to examine various topics related to CNM, including its prevalence, public attitudes toward …

The Effect Of Strain And Drug Combinations On Ketamine's Locomotor Activating Effects In Rats, Caroline K. Flagler

Theses and Dissertations

Rationale: Initially developed as an anesthetic, ketamine is now used to treat a variety of disorders, including treatment resistant depression (TRD). While ketamine appears to be a breakthrough therapy for TRD, it has many use-limiting side effects, including abuse liability, psychotomimetic effects, and sedation. Utilizing ketamine in combination with other medications, such as the monoaminergic antidepressant desipramine (DSP), opioid antagonist naltrexone (NTX), and the NMDA receptor partial agonist D-cycloserine (DCS) may reduce side-effects resulting from ketamine therapy.

Objectives: The goal of this project was to study ketamine’s adverse effects using locomotor activation in an open field as a behavioral correlate …

Advanced Modeling And Innovative Transcranial Magnetic Stimulation Coil Designs For The Treatment Of Neurological Disorders, Mohannad Tashli

Theses and Dissertations

Transcranial magnetic stimulation (TMS) is a safe, effective and non-invasive treatment for several mental and psychiatric disorders. TMS is an FDA approved treatment and is commonly applied to patients who do not respond to medications for the treatment of clinical depression, smoking cessation, obsessive-compulsive disorder and migraine. Recently, there has been an increase in the development of electromagnetic neuromodulation techniques targeted at enhancing the effectiveness of TMS devices for the treatment of mental diseases. In TMS stimulation, focality is an important factor which determines the specificity of the pulses induced in different brain tissues. The electromagnetic pulses must be confined …

Evaluating The Influence Of Concurrently Available Non-Drug Reinforcers On Drug Reinforcement Using Sophisticated Preclinical Models Of Substance Use Disorder, Madison M. Marcus

Theses and Dissertations

The maladaptive allocation of behavior towards cocaine and away from other concurrently available non-drug reinforcers (e.g., family, health, work, etc.) is a key characteristic of cocaine use disorder (CUD) that is embedded into multiple diagnostic criteria for CUD. Accordingly, basic research conducted in a drug-vs-food “choice” context has improved our fundamental knowledge of the behavioral and neurobiological mechanisms of drug reinforcement. However, to date, these preclinical studies have only been conducted with food as the alternative reinforcer. The extent to which other non-drug reinforcers compete with cocaine-taking behavior is unknown. The studies in this dissertation establish two sophisticated discrete-trial cocaine-vs-alternative …

Characterization And Decoding Of Speech Activity From Intracranial Signals, Pedram Zanganeh Soroush

Theses and Dissertations

Speech is the first and foremost means of human communication. Millions of people worldwide suffer from severe speech disorders due to neurological diseases such as amyotrophic lateral sclerosis (ALS), brain stem stroke, and severe paralysis. A speech neuroprosthesis that decodes speech directly from neural signals could dramatically improve life for these individuals. Recent studies have demonstrated that it is possible to decode and synthesize various aspects of acoustic speech directly from intracranial measurements of electrophysiological brain activity. For those who have completely lost the ability to speak, the objective is to synthesize acoustic speech directly from brain activity during imagined …

Modulation Of Epigenetic Regulatory Pathways As A Therapeutic Strategy In Breast Cancer, Ryan M. Finnegan

Theses and Dissertations

Anti-estrogens or aromatase inhibitors in combination with cyclin-dependent kinase 4 and 6 (CDK4/6) inhibitors are the current standard of care for estrogen receptor-positive (ER+) Her-2 negative metastatic breast cancer. In triple negative breast cancer, cytotoxic drugs and ionizing radiation are often used as standard of care. Although these therapies prolong progression-free survival, the growth-arrested state of residual tumor cells is clearly transient. Tumor cells that escape what might be considered a dormant state and regain proliferative capacity often acquire resistance to further therapies. Epigenetic regulation can modulate the effects of cancer therapeutics. Our studies are based upon the observation that …