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Development Of High Performance Liquid Chromatographic Separations For The Purification And Analysis Of Phospholipids And Related Liponucleotides - A New Class Of Anti-Aids Drugs, John V. Amari

Open Access Dissertations

High performance developed to isolate phospholipids and liquid chromatographic methods were and purify naturally occurring synthetic experimental Anti-AIDS liponucleotides on a preparative scale. Separations were optimized on packed with an analytical size method development column, the same media used in the preparative separations. A phospholipid class separation, on a silica stationary phase, was developed for the isolation of lecithin in chicken egg yolk. The collected fractions were analyzed for purity by analytical HPLC with UV and light scattering detection. Liponucleotides have been synthesized and required HPLC for purification. The methodology was based upon conventional phospholipid species separations on reversed-phase supports. …

Experientially-Modulated Neuronal Death In Overconnected Neural Networks, Thomas J. Skrmetti

Open Access Dissertations

This experiment was designed to examine the possible physiological mechanisms underlying the formation of critical periods in development. It was hypothesized that experientially-modulated neuronal death, coupled with an overconnected neural network, and acting early in the developmental sequence, could produce a learning effect similar to that described as a "critical period effect."

A computer-based associative memory model was used to simulate a simple neural network representing the associative cortex. Three different independent variables were manipulated in the experiment. The first was the type of connectivity matrix used when the model was initialized prior to training.

Four different developmental paradigms were …

Reading Allegory In The Old Poet And The New: The "Canterbury Tales" And The 1590 "Faerie Queene", Mark A. Sherman

Open Access Dissertations

No abstract provided.

Plankton Production Dynamics In Laguna Joyuda, Jorge R. Garcia-Sais

Open Access Dissertations

No abstract provided.

Development Of A Stages Of Change Model For Sun Exposure, Linelle M. Blais

Open Access Master's Theses

A model of readiness to reduce sun exposure was developed and tested using factor analytic, structural modeling, and cluster analytic techniques, and employing double cross-validation procedures. This model is based on the stages of change model developed by Prochaska & DiClemente (1983) which posits that people pass through a series of stages in their attempts to change behavior: Precontemplation (not intending to change); Contemplation (seriously considering change); Action (actively engaged in change); and Maintenance (successfully sustained change). A 35-item questionnaire measuring the four stages of change was administered to 595 participants in a worksite health promotion program. Six competing measurement …

The Economics Of Land Conservation: A Case Study Of Block Island, Rhode Island, Amy H. Bell

Open Access Master's Theses

In the l980's, coastal communities in the northeast were subject to heightened demand for residential and commercial land uses. This increased demand combined with the reality of a fixed resource has resulted in growing conflict between the preservation of open space and development. As municipal leaders attempt to balance expenditures with revenues, they often question if it is fiscally and economically prudent to invest in the protection of open space. Yet, environmental quality, attained in part by the conservation of open space, is often the basis for sustaining the quality of life and the economic vitality of coastal communities.

The …

A Golf Course Feasibility Study For Block Island, James F. Moran

Open Access Master's Theses

The Town of New Shoreham has expressed its desire to improve its economic base through diversification (Comprehensive Plan Citizens Participation Workshop, November, 1990). A golf course was one of the options which the town had expressed an interest in. Interest has grown to the point where a golf course study committee has been formed to assess the need for golf on Block Island.

Golf is one of the nations most popular forms of recreation (National Golf Foundation, 1989). Over the past ten years, the sport has seen great advances in the number of individuals who play the game. It is …

The Textile Finishing Industry In New England: Is Flexible Specialization Occurring?, Alison K. Nisbet

Open Access Master's Theses

This project is an in-depth study of flexible manufacturing in the New England textile finishing industry. Chapter 1 represents a literature review of the current debate surrounding the flexibility issue. Chapter 2 provides a brief outline of the methodology of the project. Chapter 3 provides a history of the textile industry, both in New England, and the United States as a whole. Chapter 4 zones in specifically on the textile finishing industry. It describes the production processes involved in finishing, and gives figures for employment within the industry at the national level. This chapter also identifies the ten key SIC …

The Effect Of Planning And Development On The Potable Groundwater Quality In Bermuda, Melody Ruth Thomas

Open Access Master's Theses

A concern for groundwater quality and its supply is universal in communities where it is either their sole or ancillary potable water supply. Bermuda is no exception, but, like many island communities, it must devise strategies to continue its status quo of self-sufficiency in regards to its water supply, although this has not always been the case. Bermuda is one of the most attractive tourist resorts islands in the Atlantic Ocean, (although it is not classified among the Caribbean Islands) therefore extreme effort is made for it to remain competitive in the tourist market. While such attempt have proven to …

An Analysis Of Serotonergic Control Of The Ventricle Of A Mollusc, Constance Leah Devlin

Open Access Dissertations

No abstract provided.

The Impact Of The Rhode Island Duplicate Prescription Law On Prescribing Practices For Schedule Ii Drugs, Bridgit A. Anness

Open Access Master's Theses

Multiple copy prescription laws have been implemented or proposed in several states to better track the distribution of drugs in Schedule II to the ultimate consumer. The states with such statutes report a 30 to 50 percent decrease in the number of Schedule II prescriptions written as well as a reduction in diversion of these drugs and forgeries. Risk factors were assessed for the effect of the Rhode Island Duplicate Prescription program on prescribers. A questionnaire was mailed to all prescribers (N=3016) registered with the Rhode Island Department of Health Division of Drug Control to prescribe Schedule II drugs. The …

Development Of A New Non-Surgical Perfusion Technique To Evaluate Nasal Drug Delivery, Polireddy Dondeti

Open Access Master's Theses

Peptide and protein drugs are increasingly becoming popular with the advances in biotechnology. Although these compounds are highly potent and display superior pharmacological profiles, there are various barriers to their systemic delivery. Most of these barriers are related to the properties of the proteins and peptides which include high large molecular size, susceptibility to proteolytic breakdown, tendency to undergo aggregation, adsorption, and denaturation. Most of these molecules are delivered by parenteral administration due to the low bioavailability obtained by the oral route. Among the noninvasive routes of drug administration, the nasal route seems to be a potential alternative to parenteral …

Nietzsche On Truth And Overcoming, Paul Swift

Open Access Master's Theses

Nietzsche on Truth and Overcoming traces the development of Friedrich Nietzsche's epistemic criticism. Nietzsche's outright denial of the existence of truth is grounded in his claim that stable metaphysical entities do not exist. The following inquiry examines Nietzsche's method of doubting which compels him to dismiss "being" as a fictitious "perspectival falsification".

Nietzsche's denial of the reality of pre-existent "being" creates problems with communicating what he means through normal language. Nietzsche on Truth and Overcoming elucidates the problems which Nietzsche creates through his uprooting of being and provides Nietzsche's hint as to where mankind might still look for …

Volunteer Community Service Work And Its Effect On The Moral Development Of Ethics Students, Judith A. Boss

Open Access Master's Theses

This study investigated the effects, in terms of moral development, of having undergraduate students engage in volunteer work with a community service agency as part of their course requirement.

The subject population consisted of 71 college ethics students enrolled in two classes of about equal size. Both classes met the same length of time, on the same days, and had the same teacher. One class, the experimental group, was required to complete twenty hours of volunteer work and keep a journal of their experiences. The other class, the control group, received a choice of a more traditional essay assignment or …

Validity Of Tasks Of Executive Functions With School-Aged Children: Potential Efficacy In Discriminating Clinical Groups, Lisa L. Weyandt

Open Access Dissertations

The purposes of the present study were (a) to investigate the performance of three groups of children, those diagnosed with Attention-deficit Hyperactivity Disorder, those diagnosed with Developmental Language Disorder, and a matched group of nondisabled children on a battery of neuropsychological tasks purported to measure executive function, and (b) to investigate the validity of tasks used to measure executive function across three age levels. A double-dissociation paradigm was used. Six executive function tasks and two nonexecutive function (i.e., vocabulary) tasks were administered to all participants in a counterbalanced order. Results revealed significant group and age effects. Significant differences were found …

The Isolation And Preliminary Characterization Of A Human Fecal Escherichia Coli Colonization Enhancement Sequence Using A Novel In Vivo Shot-Gun Cloning Assay, Robert Leslie Burghoff

Open Access Dissertations

No abstract provided.

Seasonal Patterns Of Sedimentary Carbon And Anaerobic Respiration Along A Simulated Eutrophication Gradient, P. Sampou, Candace A. Oviatt

Graduate School of Oceanography Faculty Publications

Concentrations of organic carbon and rates of dissimilative sulfate reduction in surface sediments of marine mesocosms were examined along an experimental eutrophication gradient. Phytoplankton biomass increased due to addition of inorganic nutrients (N. P, Si). This increase was especially pronounced during the winter spring diatom blooms, which increased in magnitude and duration along the nutrient gradient. Net system production in winter and spring resulted in carbon deposition and accumulation in surface sediments (maximum net accumulation 17 mol C m^-2). Benthic remineralization of carbon exceeded depositional supply during summer and fall. Sediment carbon concentrations approached background levels in December …

The Influence Of The Gulf Stream On The Regional Biogeography Of Zooplankton (Copepods), Carin Jessica Ashjian

Open Access Dissertations

No abstract provided.

On Assessing Ocean Disposal Risks: Oceanographic, Climatic, And Anthropogenic Considerations, Henry Allen Walker

Open Access Dissertations

No abstract provided.

A Neurochemical Basis For Inhibition Of Neural Activity By Ethanol, Timothy Daniel Foley

Open Access Dissertations

No abstract provided.

Topical Formulation Of Epidermal Growth Factor For Wound Healing, Mary Diana Giddins Dibiase

Open Access Dissertations

No abstract provided.

Seasonal Dynamics Of Gigaspora Gigantea And Associated Microorganisms In A Sand Dune, Pau-Ju Lee

Open Access Dissertations

No abstract provided.

The Land And Moral Responsibility In The Work Of Wendell Berry, Edward Donley Taft

Open Access Dissertations

No abstract provided.

The Effects Of Age And Occupation On Selective Attention: American Adaptation Of The Bedini Test Of Distributed Attention, Concetta Mary Di Leonardo

Open Access Dissertations

No abstract provided.

Grass Species Influence On The Fate Of Nitrogen Entrapped In Vegetated Filter Strips, Jerrell Lynn Lemunyon

Open Access Dissertations

No abstract provided.

Accumulation, Persistence, And Elimination Of Microbial Indicators By Molluscan Shellfish, William Burkhardt Iii

Open Access Dissertations

The accumulation of fecal coliforms and several other indicator microorganisms (Escherichia coli, enterococci, Clostridium perfringens, and male-specific bacteriophage) by hard-shelled clams (Mercenaria mercenaria) was investigated with regard to season and temperature. Very high rates of accumulation were found for each of these indicator organisms during distinct periods in the spring. Uptake of indicators during these periods exceeded 2 SD of the mean annual accumulation rates. Except for these periods of 'hyper-accumulation', uptake of the indicators is at least partially temperature dependent. In general, bacteriophage and C. perfringens were accumulated by clams at significantly higher rates …

The Two Hundred And Seventieth Report Of The Curricular Affairs Committee, University Of Rhode Island Faculty Senate

Faculty Senate Bills

No abstract provided.

The Two Hundred And Seventy-First Report Of The Curricular Affairs Committee, University Of Rhode Island Faculty Senate

Faculty Senate Bills

No abstract provided.

Reauthorization: S. 2724 (1990): Report 07, Susan Boren

Reauthorization: S. 2724 (1990)

No abstract provided.

Arts, Humanities, And Museums Amendments: Reports With Minority Views (1990): Report 03

Arts, Humanities, and Museums Amendments: Reports with Minority Views (1990)

No abstract provided.