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An In Situ Assessment Of Local Adaptation In A Calcifying Polychaete From A Shallow Co 2 Vent System, Noelle M. Lucey, Chiara Lombardi, Maurizio Florio, Lucia Demarchi, Matteo Nannini, Simon Rundle, Maria Cristina Gambi, Piero Calosi Oct 2016

An In Situ Assessment Of Local Adaptation In A Calcifying Polychaete From A Shallow Co 2 Vent System, Noelle M. Lucey, Chiara Lombardi, Maurizio Florio, Lucia Demarchi, Matteo Nannini, Simon Rundle, Maria Cristina Gambi, Piero Calosi

School of Biological and Marine Sciences

Ocean acidification (OA) is likely to exert selective pressure on natural populations. Our ability to predict which marine species will adapt to OA and what underlies this adaptive potential is of high conservation and resource management priority. Using a naturally low-pH vent site in the Mediterranean Sea (Castello Aragonese, Ischia) mirroring projected future OA conditions, we carried out a reciprocal transplant experiment to investigate the relative importance of phenotypic plasticity and local adaptation in two populations of the sessile, calcifying polychaete Simplaria sp. (Annelida, Serpulidae, Spirorbinae): one residing in low pH and the other from a nearby ambient (i.e. high) …


Mitochondrial Involvement In Skeletal Muscle Insulin Resistance – A Case Of Imbalanced Bioenergetics, Charles Affourtit Oct 2016

Mitochondrial Involvement In Skeletal Muscle Insulin Resistance – A Case Of Imbalanced Bioenergetics, Charles Affourtit

School of Biomedical Sciences

No abstract provided.


Assessing Spatial And Temporal Variability Of Acid-Extractable Organics In Oil Sands Process-Affected Waters, Richard A. Frank, Craig B. Milestone, Steve J. Rowland, John V. Headley, Richard J. Kavanagh, Sabine K. Lengger, Alan G. Scarlett, Charles E. West, Kerry M. Peru, L. Mark Hewitt Oct 2016

Assessing Spatial And Temporal Variability Of Acid-Extractable Organics In Oil Sands Process-Affected Waters, Richard A. Frank, Craig B. Milestone, Steve J. Rowland, John V. Headley, Richard J. Kavanagh, Sabine K. Lengger, Alan G. Scarlett, Charles E. West, Kerry M. Peru, L. Mark Hewitt

More Faculty of Science and Engineering Research

The acid-extractable organic compounds (AEOs), including naphthenic acids (NAs), present within oil sands process-affected water (OSPW) receive great attention due to their known toxicity. While recent progress in advanced separation and analytical methodologies for AEOs has improved our understanding of the composition of these mixtures, little is known regarding any variability (i.e., spatial, temporal) inherent within, or between, tailings ponds. In this study, 5 samples were collected from the same location of one tailings pond over a 2-week period. In addition, 5 samples were collected simultaneously from different locations within a tailings pond from a different mine site, as well …


Combined Effects Of Exogenous Enzymes And Probiotic On Nile Tilapia (Oreochromis Niloticus) Growth, Intestinal Morphology And Microbiome, Daniel Merrifield Oct 2016

Combined Effects Of Exogenous Enzymes And Probiotic On Nile Tilapia (Oreochromis Niloticus) Growth, Intestinal Morphology And Microbiome, Daniel Merrifield

School of Biological and Marine Sciences

No abstract provided.


Stable Isotopes And Mtdna Reveal Niche Segregation But No Evidence Of Intergradation Along A Habitat Gradient In The Lesser Whitethroat Complex (Sylvia Curruca; Passeriformes; Aves), Stephen C. Votier, Simon Aspinall, Stuart Bearhop, David Bilton, Jason Newton, Per Alström, Paul Leader, Geoff Carey, Robert W. Furnes, Urban Olsson Oct 2016

Stable Isotopes And Mtdna Reveal Niche Segregation But No Evidence Of Intergradation Along A Habitat Gradient In The Lesser Whitethroat Complex (Sylvia Curruca; Passeriformes; Aves), Stephen C. Votier, Simon Aspinall, Stuart Bearhop, David Bilton, Jason Newton, Per Alström, Paul Leader, Geoff Carey, Robert W. Furnes, Urban Olsson

School of Biological and Marine Sciences

No abstract provided.


Comparative Proteomics And Functional Analysis Reveal A Role Of Plasmodium Falciparum Osmiophilic Bodies In Malaria Parasite Transmission, P Suárez-Cortes, Vikram Sharma, Lucia Bertuccini, Giulia Costa, Naa Lamiley Bannerman, Anna Rosa Sannella, Kim Williamson, Michael Klemba, Elena A. Levashina, Edwin Lasonder, Pietro Alano Oct 2016

Comparative Proteomics And Functional Analysis Reveal A Role Of Plasmodium Falciparum Osmiophilic Bodies In Malaria Parasite Transmission, P Suárez-Cortes, Vikram Sharma, Lucia Bertuccini, Giulia Costa, Naa Lamiley Bannerman, Anna Rosa Sannella, Kim Williamson, Michael Klemba, Elena A. Levashina, Edwin Lasonder, Pietro Alano

School of Biomedical Sciences

An essential step in the transmission of the malaria parasite to the Anopheles vector is the transformation of the mature gametocytes into gametes in the mosquito gut, where they egress from the erythrocytes and mate to produce a zygote, which matures into a motile ookinete. Osmiophilic bodies are electron dense secretory organelles of the female gametocytes which discharge their contents during gamete formation, suggestive of a role in gamete egress. Only one protein with no functional annotation, Pfg377, is described to specifically reside in osmiophilic bodies in Plasmodium falciparum. Importantly, Pfg377 defective gametocytes lack osmiophilic bodies and fail to infect …


Increased Peptide Yy Blood Concentrations, Not Decreased Acyl-Ghrelin, Are Associated With Reduced Hunger And Food Intake In Healthy Older Women: Preliminary Evidence., Mary Hickson, Charlotte Moss, Waljit S. Dhillo, Jeanne Bottin, Gary Frost Oct 2016

Increased Peptide Yy Blood Concentrations, Not Decreased Acyl-Ghrelin, Are Associated With Reduced Hunger And Food Intake In Healthy Older Women: Preliminary Evidence., Mary Hickson, Charlotte Moss, Waljit S. Dhillo, Jeanne Bottin, Gary Frost

School of Health Professions

With ageing there is frequently a loss of appetite, termed anorexia of ageing, which can result in under-nutrition. We do not know how appetite control alters with ageing. The objective of this study was to investigate whether differences in the release of, and response to, gastrointestinal appetite hormones is altered in young compared to old healthy volunteers. We hypothesised that an increase in PYY and GLP-1 or a decrease ghrelin may result in a decreased appetite. A comparative experimental design, using a cross-sectional sample of ages from a healthy population, matched for sex and BMI was used. The study compared …


Impacts Of Port Development On Estuarine Morphodynamics: Ribadeo (Spain), M Prumm, G Iglesias Oct 2016

Impacts Of Port Development On Estuarine Morphodynamics: Ribadeo (Spain), M Prumm, G Iglesias

School of Engineering, Computing and Mathematics

Port developments in estuaries can significantly affect estuarine dynamics, causing hydrodynamic changes that can in turn affect sediment transport patterns. Understanding these impacts is crucial in view of the socioeconomic relevance of estuaries and their high sensitivity – as the complex natural systems that they are. The objective of this work is to investigate the impact of port expansion on estuarine dynamics through a case study. Process-based models are implemented to investigate the morphodynamic response of the estuary to the expansion of the Port of Ribadeo. The models simulate the hydrodynamics and sediment transport of the estuary with and without …


Implementation Of A Modular Growing When Required Neural Gas Architecture For Recognition Of Falls, F Belmonte Klein, Ac Cangelosi, Ks Štěpánová Sep 2016

Implementation Of A Modular Growing When Required Neural Gas Architecture For Recognition Of Falls, F Belmonte Klein, Ac Cangelosi, Ks Štěpánová

School of Engineering, Computing and Mathematics

In this paper we aim for the replication of a state of the art architecture for recognition of human actions using skeleton poses obtained from a depth sensor. We review the usefulness of accurate human action recognition in the field of robotic elderly care, focusing on fall detection. We attempt fall recognition using a chained Growing When Required neural gas classifier that is fed only skeleton joints data. We test this architecture against Recurrent SOMs (RSOMs) to classify the TST Fall detection database ver. 2, a specialised dataset for fall sequences. We also introduce a simplified mathematical model of falls …


The Regulation Of Bone Turnover In Ameloblastoma Using An Organotypic In Vitro Co-Culture Model, Tuula M. Eriksson, Richard M. Day, Stefano Fedele, Vehid M. Salih Sep 2016

The Regulation Of Bone Turnover In Ameloblastoma Using An Organotypic In Vitro Co-Culture Model, Tuula M. Eriksson, Richard M. Day, Stefano Fedele, Vehid M. Salih

Peninsula Dental School

No abstract provided.


Graceful Degradation Under Noise On Brain Inspired Robot Controllers, R De Azambuja, Fb Klein, Mf Stoelen, Sv Adams, A Cangelosi Sep 2016

Graceful Degradation Under Noise On Brain Inspired Robot Controllers, R De Azambuja, Fb Klein, Mf Stoelen, Sv Adams, A Cangelosi

School of Engineering, Computing and Mathematics

How can we build robot controllers that are able to work under harsh conditions, but without experiencing catastrophic failures? As seen on the recent Fukushima’s nuclear disaster, standard robots break down when exposed to high radiation environments. Here we present the results from two arrangements of Spiking Neural Networks, based on the Liquid State Machine (LSM) framework, that were able to gracefully degrade under the effects of a noisy current injected directly into each simulated neuron. These noisy currents could be seen, in a simplified way, as the consequences of exposition to non-destructive radiation. The results show that not only …


Permanent Draft Genome Of Thermithiobaclillus Tepidarius Dsm 3134T, A Moderately Thermophilic, Obligately Chemolithoautotrophic Member Of The Acidithiobacillia, Rich Boden, Lee P. Hutt, Marcel Huntemann, Alicia Clum, Manoj Pillay, Krishnaveni Palaniappan, Neha Varghese, Natalia Mikhailova, Dimitrios Stamatis, Tatiparthi Reddy, Chew Yee Ngan, Chris Daum, Nicole Shapiro, Victor Markowitz, Natalia Ivanova, Tanja Woyke, Nikos Kyrpides Sep 2016

Permanent Draft Genome Of Thermithiobaclillus Tepidarius Dsm 3134T, A Moderately Thermophilic, Obligately Chemolithoautotrophic Member Of The Acidithiobacillia, Rich Boden, Lee P. Hutt, Marcel Huntemann, Alicia Clum, Manoj Pillay, Krishnaveni Palaniappan, Neha Varghese, Natalia Mikhailova, Dimitrios Stamatis, Tatiparthi Reddy, Chew Yee Ngan, Chris Daum, Nicole Shapiro, Victor Markowitz, Natalia Ivanova, Tanja Woyke, Nikos Kyrpides

School of Biological and Marine Sciences

Thermithiobacillus tepidarius DSM 3134T was originally isolated (1983) from the waters of a sulfidic spring entering the Roman Baths (Temple of Sulis-Minerva) at Bath, United Kingdom and is an obligate chemolithoautotroph growing at the expense of reduced sulfur species. This strain has a genome size of 2,958,498 bp. Here we report the genome sequence, annotation and characteristics. The genome comprises 2,902 protein coding and 66 RNA coding genes. Genes responsible for the transaldolase variant of the Calvin-Benson-Bassham cycle were identified along with a biosynthetic horseshoe in lieu of Krebs' cycle sensu stricto. Terminal oxidases were identified, viz. cytochrome c …


Unexpected Removal Of The Most Neutral Cationic Pharmaceutical In River Waters, Mark F. Fitzsimons, Alan D. Tappin, Alan J. Mccarthy, J. Paul Loughnane Sep 2016

Unexpected Removal Of The Most Neutral Cationic Pharmaceutical In River Waters, Mark F. Fitzsimons, Alan D. Tappin, Alan J. Mccarthy, J. Paul Loughnane

School of Geography, Earth and Environmental Sciences

No abstract provided.


Concurrent Investigation Of Global Motion And Form Processing In Amblyopia: An Equivalent Noise Approach, Mahesh R. Joshi, Anita J. Simmers, Seong T. Jeon Sep 2016

Concurrent Investigation Of Global Motion And Form Processing In Amblyopia: An Equivalent Noise Approach, Mahesh R. Joshi, Anita J. Simmers, Seong T. Jeon

School of Health Professions

No abstract provided.


Ocean Acidification Reduces Demersal Zooplankton That Reside In Tropical Coral Reefs, Joy N. Smith, G De’Ath, Claudio Richter, Astrid Cornils, Jason M. Hall-Spencer, Katharina E. Fabricius Sep 2016

Ocean Acidification Reduces Demersal Zooplankton That Reside In Tropical Coral Reefs, Joy N. Smith, G De’Ath, Claudio Richter, Astrid Cornils, Jason M. Hall-Spencer, Katharina E. Fabricius

School of Biological and Marine Sciences

No abstract provided.


The London Workshop On The Biogeography And Connectivity Of The Clarion-Clipperton Zone, A Glover, Et Al Sep 2016

The London Workshop On The Biogeography And Connectivity Of The Clarion-Clipperton Zone, A Glover, Et Al

School of Biological and Marine Sciences

Recent years have seen a rapid increase in survey and sampling expeditions to the Clarion-Clipperton Zone (CCZ) abyssal plain, a vast area of the central Pacific that is currently being actively explored for deep-sea minerals (ISA, 2016). Critical to the development of evidence-based environmental policy in the CCZ are data on the biogeography and connectivity of species at a CCZ-regional level. The London Workshop on the Biogeography and Connectivity of the CCZ was convened to support the integration and synthesis of data from European Union (EU) CCZ projects, supported by the EU Managing Impacts of Deep-Sea Resource Exploitation (MIDAS) and …


The Impact Of Natural And Anthropogenic Dissolved Organic Carbon (Doc), And Ph On The Toxicity Of Triclosan To The Crustacean Gammarus Pulex (L.)., Sean D.W. Comber, Christopher J. Rowett, Thomas H. Hutchinson Sep 2016

The Impact Of Natural And Anthropogenic Dissolved Organic Carbon (Doc), And Ph On The Toxicity Of Triclosan To The Crustacean Gammarus Pulex (L.)., Sean D.W. Comber, Christopher J. Rowett, Thomas H. Hutchinson

School of Geography, Earth and Environmental Sciences

Regulatory ecotoxicology testing rarely accounts for the influence of natural water chemistry on the bioavailability and toxicity of a chemical. Therefore, this study identifies whether key omissions in relation to Dissolved Organic Carbon (DOC) and pH have an impact on measured effect concentrations (EC). Laboratory ecotoxicology tests were undertaken for the widely used antimicrobial compound triclosan, using adult Gammarus pulex (L.), a wild-type amphipod using synthetic fresh water, humic acid solutions and wastewater treatment works effluent. The toxicity of triclosan was tested at two different pHs of 7.3 and 8.4, with and without the addition of DOC and 24 and …


Mboat7 Rs641738 Increases Risk Of Liver Inflammation And Transition To Fibrosis In Chronic Hepatitis C., Khaled Thabet, Anastasia Asimakopoulos, Maryam Shojaei, Manuel Romero-Gomez, Alessandra Mangia, William L. Irving, Thomas Berg, Gregory J. Dore, Henning Grønbæk, David Sheridan, Maria Lorena Abate, Elisabetta Bugianesi, Martin Weltman, Lindsay Mollison, Wendy Cheng, Stephen Riordan, Janett Fischer, Ulrich Spengler, Jacob Nattermann, Ahmed Wahid, Angela Rojas, Rose White, Mark W. Douglas, Duncan Mcleod, Elizabeth Powell, Christopher Liddle, David Van Der Poorten, Jacob George, Mohammed Eslam Sep 2016

Mboat7 Rs641738 Increases Risk Of Liver Inflammation And Transition To Fibrosis In Chronic Hepatitis C., Khaled Thabet, Anastasia Asimakopoulos, Maryam Shojaei, Manuel Romero-Gomez, Alessandra Mangia, William L. Irving, Thomas Berg, Gregory J. Dore, Henning Grønbæk, David Sheridan, Maria Lorena Abate, Elisabetta Bugianesi, Martin Weltman, Lindsay Mollison, Wendy Cheng, Stephen Riordan, Janett Fischer, Ulrich Spengler, Jacob Nattermann, Ahmed Wahid, Angela Rojas, Rose White, Mark W. Douglas, Duncan Mcleod, Elizabeth Powell, Christopher Liddle, David Van Der Poorten, Jacob George, Mohammed Eslam

Peninsula Medical School

No abstract provided.


Toward A Multi-Agent System For Marine Observation, R Polvara, S Sharma, R Sutton, J Wan, A Manning Sep 2016

Toward A Multi-Agent System For Marine Observation, R Polvara, S Sharma, R Sutton, J Wan, A Manning

School of Engineering, Computing and Mathematics

No abstract provided.


Heterokairy: A Significant Form Of Developmental Plasticity?, S. D. Rundle, J. I. Spicer Sep 2016

Heterokairy: A Significant Form Of Developmental Plasticity?, S. D. Rundle, J. I. Spicer

School of Biological and Marine Sciences

No abstract provided.


Proteomics Of Human Dendritic Cell Subsets Reveals Subset-Specific Surface Markers And Differential Inflammasome Function., K Worah, Ts Mathan, Tp Vu Manh, S Keerthikumar, Et Al Sep 2016

Proteomics Of Human Dendritic Cell Subsets Reveals Subset-Specific Surface Markers And Differential Inflammasome Function., K Worah, Ts Mathan, Tp Vu Manh, S Keerthikumar, Et Al

School of Biomedical Sciences

Dendritic cells (DCs) play a key role in orchestrating adaptive immune responses. In human blood, three distinct subsets exist: plasmacytoid DCs (pDCs) and BDCA3+ and CD1c+ myeloid DCs. In addition, a DC-like CD16+ monocyte has been reported. Although RNA-expression profiles have been previously compared, protein expression data may provide a different picture. Here, we exploited label-free quantitative mass spectrometry to compare and identify differences in primary human DC subset proteins. Moreover, we integrated these proteomic data with existing mRNA data to derive robust cell-specific expression signatures with more than 400 differentially expressed proteins between subsets, forming a solid basis for …


Ret Is Essential To Mediate Gdnf’S Neuroprotective And Neuroregenerative Effect In A Parkinson Disease Mouse Model, Anja Drinkut, Karsten Tillack, Durga P. Meka, Jorg B. Schulz, Sebastian Kügler, Edgar R. Kramer Sep 2016

Ret Is Essential To Mediate Gdnf’S Neuroprotective And Neuroregenerative Effect In A Parkinson Disease Mouse Model, Anja Drinkut, Karsten Tillack, Durga P. Meka, Jorg B. Schulz, Sebastian Kügler, Edgar R. Kramer

Peninsula Medical School

No abstract provided.


Determination Of Rare Earth Elements In Natural Water Samples – A Review Of Sample Separation, Preconcentration And Direct Methodologies, Andrew Fisher, Derya Kara Sep 2016

Determination Of Rare Earth Elements In Natural Water Samples – A Review Of Sample Separation, Preconcentration And Direct Methodologies, Andrew Fisher, Derya Kara

School of Geography, Earth and Environmental Sciences

This review discusses and compares the methods given for the determination of rare earth elements (REE) in natural water samples, including sea, river, lake, tap, ground and waste waters as well as Antarctic ice. Since REE are at very low concentrations in natural waters, numerous different preconcentration methods have been proposed to enable their measurement. These include liquid liquid extraction, dispersive liquid-liquid micro-extraction and solidified floating drop micro-extraction. In addition to liquid-liquid extraction methods, solid phase extraction using commercial resins, resins made in-house, silica-based exchange materials and other solid media is also discussed. These and other techniques such as precipitation/co-precipitation …


Frontiers: Expanding Musical Imagination With Audience Participation, M Gimenes, P-E Largeron, Er Miranda Sep 2016

Frontiers: Expanding Musical Imagination With Audience Participation, M Gimenes, P-E Largeron, Er Miranda

School of Art, Design and Architecture

No abstract provided.


Resilience Of Small-Scale Societies’ Livelihoods: A Framework For Studying The Transition From Food Gathering To Food Production, C Lancelotti, D Zurro, Nj Whitehouse, M Madella, Et Al Sep 2016

Resilience Of Small-Scale Societies’ Livelihoods: A Framework For Studying The Transition From Food Gathering To Food Production, C Lancelotti, D Zurro, Nj Whitehouse, M Madella, Et Al

School of Geography, Earth and Environmental Sciences

The origins of agriculture and the shift from hunting and gathering to committed agriculture is regarded as one of the major transitions in human history. Archeologists and anthropologists have invested significant efforts in explaining the origins of agriculture. A period of gathering intensification and experimentation and pursuing a mixed economic strategy seems the most plausible explanation for the transition to agriculture and provides an approach to study a process in which several nonlinear processes may have played a role. However, the mechanisms underlying the transition to full agriculture are not completely clear. This is partly due to the nature of …


Eco-Engineered Rock Pools: A Concrete Solution To Biodiversity Loss And Urban Sprawl In The Marine Environment, Lb Firth, Ka Browne, Am Knights, Sj Hawkins, R Nash Sep 2016

Eco-Engineered Rock Pools: A Concrete Solution To Biodiversity Loss And Urban Sprawl In The Marine Environment, Lb Firth, Ka Browne, Am Knights, Sj Hawkins, R Nash

School of Geography, Earth and Environmental Sciences

In coastal habitats artificial structures typically support lower biodiversity and can support greater numbers of non-native and opportunistic species than natural rocky reefs. Eco-engineering experiments are typically trialed to succeed; but arguably as much is learnt from failure than from success. Our goal was to trial a generic, cost effective, eco-engineering technique that could be incorporated into rock armouring anywhere in the world. Artificial rock pools were created from manipulated concrete between boulders on the exposed and sheltered sides of a causeway. Experimental treatments were installed in locations where they were expected to fail and compared to controls installed in …


Seabird Diving Behaviour Reveals The Functional Significance Of Shelf-Sea Fronts As Foraging Hotspots, S. L. Cox, P. I. Miller, C. B. Embling, K. L. Scales, A. W.J. Bicknell, P. J. Hosegood, G. Morgan, S. N. Ingram, S. C. Votier Sep 2016

Seabird Diving Behaviour Reveals The Functional Significance Of Shelf-Sea Fronts As Foraging Hotspots, S. L. Cox, P. I. Miller, C. B. Embling, K. L. Scales, A. W.J. Bicknell, P. J. Hosegood, G. Morgan, S. N. Ingram, S. C. Votier

School of Biological and Marine Sciences

No abstract provided.


Genome-Wide Association Study Identifies Sestd1 As A Novel Risk Gene For Lithium-Responsive Bipolar Disorder, J Song, Se Bergen, Et Al Sep 2016

Genome-Wide Association Study Identifies Sestd1 As A Novel Risk Gene For Lithium-Responsive Bipolar Disorder, J Song, Se Bergen, Et Al

School of Biomedical Sciences

Lithium is the mainstay prophylactic treatment for bipolar disorder (BD), but treatment response varies considerably across individuals. Patients who respond well to lithium treatment might represent a relatively homogeneous subtype of this genetically and phenotypically diverse disorder. Here, we performed genome-wide association studies (GWAS) to identify (i) specific genetic variations influencing lithium response and (ii) genetic variants associated with risk for lithium-responsive BD. Patients with BD and controls were recruited from Sweden and the United Kingdom. GWAS were performed on 2698 patients with subjectively defined (self-reported) lithium response and 1176 patients with objectively defined (clinically documented) lithium response. We next …


Morpho-Sedimentary Dynamics Of A Micro-Tidal Mixed Sand And Gravel Beach, Playa Granada, Southern Spain, Rafael J. Bergillos, Miguel Ortega-Sánchez, Gerd Masselink, Miguel A. Losada Sep 2016

Morpho-Sedimentary Dynamics Of A Micro-Tidal Mixed Sand And Gravel Beach, Playa Granada, Southern Spain, Rafael J. Bergillos, Miguel Ortega-Sánchez, Gerd Masselink, Miguel A. Losada

School of Biological and Marine Sciences

No abstract provided.


Multi-Year Assessment Of Coastal Planktonic Fungi Reveals Environmental Drivers Of Diversity And Abundance, Joe D. Taylor, Michael Cunliffe Sep 2016

Multi-Year Assessment Of Coastal Planktonic Fungi Reveals Environmental Drivers Of Diversity And Abundance, Joe D. Taylor, Michael Cunliffe

School of Biological and Marine Sciences

Abstract Mycoplankton have so far been a neglected component of pelagic marine ecosystems, having been poorly studied relative to other plankton groups. Currently, there is a lack of understanding of how mycoplankton diversity changes through time, and the identity of controlling environmental drivers. Using Fungi-specific high-throughput sequencing and quantitative PCR analysis of plankton DNA samples collected over 6 years from the coastal biodiversity time series site Station L4 situated off Plymouth (UK), we have assessed changes in the temporal variability of mycoplankton diversity and abundance in relation to co-occurring environmental variables. Mycoplankton diversity at Station L4 was dominated by Ascomycota, …