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Articles 1831 - 1860 of 6794
Full-Text Articles in Entire DC Network
Neonatal Sepsis: A Systematic Review Of Core Outcomes From Randomised Clinical Trials, Cían J. Henry, Gergana Semova, Ellen Barnes, Isabel Cotter, Tara Devers, Aisyah Rafaee, Andreea Slavescu, Niamh O. Cathain, Danielle Mccollum, Edna Roche, David Mockler, John Allen, Judith Meehan, Claus Klingenberg, Jos M. Latour, Den Hoogen A Van, Tobias Strunk, Eric Giannoni, Luregn J. Schlapbach, Marina Degtyareva, Frans B. Plötz, Boode Wp De, Lars Naver, James L. Wynn, Helmut Küster, Jan Janota, Fleur M. Keij, Irwin K.M. Reiss, Joseph M. Bliss, Joseph M. Bliss, Joyce M. Koenig, Mark A. Turner, Christopher Gale, Eleanor J. Molloy
Neonatal Sepsis: A Systematic Review Of Core Outcomes From Randomised Clinical Trials, Cían J. Henry, Gergana Semova, Ellen Barnes, Isabel Cotter, Tara Devers, Aisyah Rafaee, Andreea Slavescu, Niamh O. Cathain, Danielle Mccollum, Edna Roche, David Mockler, John Allen, Judith Meehan, Claus Klingenberg, Jos M. Latour, Den Hoogen A Van, Tobias Strunk, Eric Giannoni, Luregn J. Schlapbach, Marina Degtyareva, Frans B. Plötz, Boode Wp De, Lars Naver, James L. Wynn, Helmut Küster, Jan Janota, Fleur M. Keij, Irwin K.M. Reiss, Joseph M. Bliss, Joseph M. Bliss, Joyce M. Koenig, Mark A. Turner, Christopher Gale, Eleanor J. Molloy
School of Nursing and Midwifery
Abstract Background The lack of a consensus definition of neonatal sepsis and a core outcome set (COS) proves a substantial impediment to research that influences policy and practice relevant to key stakeholders, patients and parents. Methods A systematic review of the literature was performed according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. In the included studies, the described outcomes were extracted in accordance with the provisions of the Core Outcome Measures in Effectiveness Trials (COMET) handbook and registered. Results Among 884 abstracts identified, 90 randomised controlled trials (RCTs) were included in this review. Only 30 …
Morphological And Molecular Assessment Of Lithophyllum Okamurae With The Description Of L. Neo-Okamurae Sp. Nov. (Corallinales, Rhodophyta), Aki Kato, Daniela Basso, Annalisa Caragnano, Graziella Rodondi, Gall L Le, Viviana Peña, Jason M. Hall-Spencer, Masasuke Baba
Morphological And Molecular Assessment Of Lithophyllum Okamurae With The Description Of L. Neo-Okamurae Sp. Nov. (Corallinales, Rhodophyta), Aki Kato, Daniela Basso, Annalisa Caragnano, Graziella Rodondi, Gall L Le, Viviana Peña, Jason M. Hall-Spencer, Masasuke Baba
School of Biological and Marine Sciences
No abstract provided.
Receipt Of Help By People With Cognitive Impairment: Results From The English Longitudinal Study Of Ageing, S Read, B Hu, J Dixon, N Brimblecombe, Et Al
Receipt Of Help By People With Cognitive Impairment: Results From The English Longitudinal Study Of Ageing, S Read, B Hu, J Dixon, N Brimblecombe, Et Al
Peninsula Medical School
OBJECTIVES: We investigated whether people with dementia or low memory/orientation reported more help misaligned with needs - more unmet need and/or more unrequired help - than other people with similar levels of functional limitation, and examined associations with quality of life. METHODS: From pooled English Longitudinal Study of Ageing data from waves 6, 7, and 8, we identified community-dwelling people aged 50+ with: dementia (n= 405); low memory/orientation but no dementia (n= 4520); and intact memory/orientation (n= 10,264). Unmet need (not receiving help for the functional limitation) and unrequired help (receipt of help without the respective functional limitation) were used …
Covid-19 Pandemic Impact On Psychotropic Prescribing For Adults With Intellectual Disability: An Observational Study In English Specialist Community Services, Danial Naqvi, Bhathika Perera, Sarah Mitchell, Rory Sheehan, Rohit Shankar
Covid-19 Pandemic Impact On Psychotropic Prescribing For Adults With Intellectual Disability: An Observational Study In English Specialist Community Services, Danial Naqvi, Bhathika Perera, Sarah Mitchell, Rory Sheehan, Rohit Shankar
Peninsula Medical School
Background Coronavirus disease 2019 (COVID-19) has had a disproportionate impact on people with intellectual disability (PwID). PwID are at higher risk of mental illness and receive psychotropic prescribing 'off licence' also, to manage distress behaviour. The lockdown and reduction of multidisciplinary face-to-face appointments had an impact on care delivery, the recourse possibly being psychotropic prescribing. It is imperative to comprehend the influence the pandemic had on psychotropic prescribing patterns to enable future planning. Aims The aim was to understand the impact of the pandemic by comparing psychotropic prescribing patterns during the England lockdown with the prescribing patterns before lockdown in …
Estuarine Infauna Within Incidentally Retained Sediment In Artificial Rockpools, Jessica R. Bone, Rick Stafford, Alice E. Hall, Ian Boyd, Nigel George, Roger J.H. Herbert
Estuarine Infauna Within Incidentally Retained Sediment In Artificial Rockpools, Jessica R. Bone, Rick Stafford, Alice E. Hall, Ian Boyd, Nigel George, Roger J.H. Herbert
School of Biological and Marine Sciences
Artificial coastal structures (ACSs) are primarily designed to provide services for human use, such as flood defence or shipping, and are generally poor for marine biodiversity. Consequently, there has been significant research effort to enhance these hard structures to increase biodiversity and habitat availability via eco-engineering. On seawalls and breakwaters, this has included the creation of habitats for benthic species found on natural rocky shores, including the provision of cracks, crevices and water retaining features, such as artificial rockpools. When sediment retention in these features has occurred, it has often been deemed detrimental to the overarching aim of the intervention. …
A Qualitative Exploration Of The Media’S Influence On Uk Women’S Views Of Breastfeeding, Kiron Srivastava, Alyson Norman, Samantha Mortimer
A Qualitative Exploration Of The Media’S Influence On Uk Women’S Views Of Breastfeeding, Kiron Srivastava, Alyson Norman, Samantha Mortimer
School of Psychology
No abstract provided.
The Psychological Impact Of Sharps Injuries Sustained By Medical Students, Kevin Hambridge
The Psychological Impact Of Sharps Injuries Sustained By Medical Students, Kevin Hambridge
School of Nursing and Midwifery
Much is known and reported about sharps injuries among healthcare workers, but there has been a lack of published evidence regarding the psychological impact of sharps injuries among medical students. The purpose of this narrative review was to discover the psychological impact of sharps injuries within the medical student population. Medical, health and psychology databases were searched for studies written in the English language and published between 1980 and 2021. The review identified six studies conducted in six countries which described the psychological impacts of sharps injuries among medical students as being fear, anxiety, depression and post-traumatic stress disorder. The …
Machine Learning-Based Exploration Of Blood-Based Biomarkers For Alzheimer’S Disease Diagnosis, Chima Stanley Eke
Machine Learning-Based Exploration Of Blood-Based Biomarkers For Alzheimer’S Disease Diagnosis, Chima Stanley Eke
School of Engineering, Computing and Mathematics Theses
Alzheimer’s disease (AD) is a neurodegenerative disease with typical clinical symptoms in the form of progressive cognitive impairment and memory loss. To facilitate early diagnosis of AD and a greater understanding of the mechanisms underlying its clinical expression, the use of biomarkers is necessary. Furthermore, it is believed that biomarkers provide a more objective and accessible means of diagnosis. Currently, established biomarkers include neuroimaging markers, such as those based on positron emission tomography (PET), and biochemical markers such as cerebrospinal fluid (CSF) markers. However, neuroimaging is expensive and may not be widely available and CSF testing is invasive. Blood-based biomarkers …
Biosensing With Back-Gated Graphene Field Effect Transistors, Benjamin O'Driscoll
Biosensing With Back-Gated Graphene Field Effect Transistors, Benjamin O'Driscoll
School of Engineering, Computing and Mathematics Theses
The widespread existence of the heavy metal lead in the environment is a severe threat to the health of humans. Lead is a neurotoxin that accumulates over time in the body restricting the cognitive, behavioural and psychological development of children. Since water is one exposure route for chemical hazards like Pb2+ it is envisioned that monitoring drinking water sources with low-cost, sensitive and field-suitable devices is one way that human exposure can be limited. Herein presents graphene field effect transistors (GFETs) functionalised with aptamers as bioreceptors, for the specific detection of Pb2+ ions in water. Functionalising GFETs with bioreceptors facilitates …
Mining Marine Environments For Novel Antimicrobial Biologics, Matthew James Koch
Mining Marine Environments For Novel Antimicrobial Biologics, Matthew James Koch
School of Biomedical Sciences Theses
Deaths attributable to antimicrobial resistance (AMR) are predicted to rise from 700,000 per year now to 10 million by 2050. There is an urgent need for new antibiotics to meet the threat posed by AMR; the WHO recently reported that there are not enough antibiotics in development to meet this need. The sponge microbiota has emerged as one of the most prolific sources of novel antimicrobial candidates from marine environments in recent decades. The majority of work on sponge microbiology, however, has been carried out on shallow-water sponges of the Demosponge Class. This work explores the cultivable diversity and antimicrobial …
Acute-Lps Mediated Myelin Injury, Gideon Stone
Acute-Lps Mediated Myelin Injury, Gideon Stone
School of Biomedical Sciences Theses
Background: Multiple Sclerosis is a notorious neurological disease strongly linked to auto-immune pathogenesis and involvement of inflammatory cytokines, resulting in CNS white matter injury. To date, there is no known cure and a limited number of successful treatments, with the exact pathogenic mechanisms of the disease being unknown. Due to this there is a high demand for the development of effective treatments. With the primary use of anti-inflammatory treatments, the symptoms can be significantly reduced, and the occurrence of relapses and exacerbations can be managed. The use of animal models such as EAE and cuprizone has helped drastically with the …
Would Earth Law Change The Face Of Environmental Law In England?, Hetty Summerhayes
Would Earth Law Change The Face Of Environmental Law In England?, Hetty Summerhayes
Plymouth Law Review
This article aims to compare Environmental Law in England with the established body of Earth Law which currently exists internationally. It provides an analysis of English Law as it applies to marine protection, environmental permitting and wildlife conservation and critically analyses whether they are doing enough to ensure a conservationist regime. Further, it explores the Earth Law movement and how it might influence and change the application of Environmental Law in England. Particular attention is paid to academics and writers such as Christopher Stone, Rachel Carson and Cormac Cullinan. Examining the shift we as human beings must take from an …
Thought And Decision: Differences And Overlap In Environmental And Legal Studies, Robert Nutkins
Thought And Decision: Differences And Overlap In Environmental And Legal Studies, Robert Nutkins
Plymouth Law Review
No abstract provided.
When Do You Break The Glass Ceiling? A Gender-Diverse Student's Experience Of The Legal World, Sami Fison
When Do You Break The Glass Ceiling? A Gender-Diverse Student's Experience Of The Legal World, Sami Fison
Plymouth Law Review
No abstract provided.
Evaluating The Bude Water Vole Reintroduction Project And The Factors Which Determined The Successes And Failures, Teagen Louise Hill
Evaluating The Bude Water Vole Reintroduction Project And The Factors Which Determined The Successes And Failures, Teagen Louise Hill
School of Biological and Marine Sciences Theses
Water voles (Arvicola amphibius), once a widespread species in Britain, became the fastest declining British mammal due to habitat fragmentation and North American mink (Neovison vison) introduction. Bude catchment (North Cornwall, England) was the location of the first water vole release project in Cornwall and has been closely monitored since the first releases in 2013. Latrines, being the most accurate field sign, were recorded twice a year, alongside burrows and feeding signs, giving an indication to the presence of voles in and around the release locations. In the Bude release catchment the presence of water voles was strongly correlated with …
The Genetic Diversity And Distribution Of Two Endangered Pit Vipers (Bothriechis Marchi And Cerrophidion Wilsoni) Within Cusuco National Park, Honduras, Debbie Starbuck
The Genetic Diversity And Distribution Of Two Endangered Pit Vipers (Bothriechis Marchi And Cerrophidion Wilsoni) Within Cusuco National Park, Honduras, Debbie Starbuck
School of Biological and Marine Sciences Theses
The current extinction rate is being increasingly recognised as an escalating issue, with observations still indicating that humans are the leading cause of a sixth mass extinction. Cloud forests in particular are home to a variety of threatened species, however, many of these forests are highly fragmented resulting in many species and populations existing in isolation. These forests have become centres of endemism for many species, leading to a high representation within global biodiversity hotspots and “irreplaceable” protected areas. This study primarily investigates the genetic diversity and distribution of two recently re-classified, sympatric pit vipers (Bothriechis marchi and Cerrophidion wilsoni) …
Evaluation Of The Anticancer And Anti-Inflammatory Potential Of The Brown Seaweed Cystoseira, Ahmad A Farag Mansur
Evaluation Of The Anticancer And Anti-Inflammatory Potential Of The Brown Seaweed Cystoseira, Ahmad A Farag Mansur
School of Biological and Marine Sciences Theses
Cystoseira is abundant in bioactive chemicals that have been emphasized for their pharmacological value as plentiful and typically safe alternatives, offering a viable technique for treating cancer and inflammatory diseases. However, evaluating the effect of seasonality and extraction methods on Cystoseira chemical composition and cytotoxicity activity are still not thoroughly investigated. This study investigates the effect of seasonal variations and extraction methods of the Cystoseira extracts on the chemical composition and cytotoxicity activity on human cancer cell lines. C. tamariscifolia, C. crinita and C. compressa, were collected from the UK and Libya and colourimetric techniques were used to measure the …
The Application Of Habitat Suitability Modelling To Mapping Vme Distribution In The Deep Sea To Inform Spatial Management, Kyran Graves
The Application Of Habitat Suitability Modelling To Mapping Vme Distribution In The Deep Sea To Inform Spatial Management, Kyran Graves
School of Biological and Marine Sciences Theses
As the development of new technologies continues, so do industrial activities. As a result, such industries can extract natural resources and use the marine environment at deeper and deeper depths, for example, fisheries, oil and gas, submarine cabling, and – the latest emergence – deep-sea mining. Despite these developments, the majority of the deep ocean, including national waters and the High Seas, remains unmapped. The absence of data across large swathes of the deep sea means that conducting adequate environmental impact assessments when new activities are proposed is difficult, and what data is available is often sparse. Predictive habitat models …
A Biologically Meaningful Evaluation Of Phenological Responses To Climate Change, Nicola Mansfield
A Biologically Meaningful Evaluation Of Phenological Responses To Climate Change, Nicola Mansfield
School of Biological and Marine Sciences Theses
Phenological change is widely regarded as an important biological indicator of contemporary climate change. Increasing global temperatures have been identified as driving changes in the timing of key life-cycle events across a wide range of organisms. Estimates of phenological change are often based on single measure of phenology, such as the date of the first flower to bloom or the first migrant of the season to arrive. However, this approach is unlikely to be representative of the population as a whole and ignores important information regarding, for example, the duration of the phenomenon, its temporal skew, and its shape. A …
Emerging Contradictions In The Enforcement Of Bird Hunting Regulations In Malta, Bertie Ferns, Brian Campbell, Diogo Veríssimo
Emerging Contradictions In The Enforcement Of Bird Hunting Regulations In Malta, Bertie Ferns, Brian Campbell, Diogo Veríssimo
School of Law, Humanities and Social Sciences
No abstract provided.
Emotional And Behavioural Responses To Covid-19: Explanations From Three Key Models Of Personality, Alison M. Bacon, Dino Krupić, Nese Caki, Philip J. Corr
Emotional And Behavioural Responses To Covid-19: Explanations From Three Key Models Of Personality, Alison M. Bacon, Dino Krupić, Nese Caki, Philip J. Corr
School of Psychology
This review appraises evidence for the role of personality in Covid-19 related emotions and behaviours. Three key models of personality are considered: the Five factor Model, HEXACO model and Reinforcement Sensitivity Theory. In line with personality research more generally, most studies focus on the Five-Factor model. Key findings are that neuroticism is most associated with poor mental health, and extraversion is associated with a reluctance to socially isolate. Conscientiousness predicts compliance with safety guidelines, but also with fewer prosocial behaviours, particularly stockpiling. Research within the HEXACO framework largely confirms these findings, especially for emotionality and mental health. The additional HEXACO …
Room To Breathe: Using Adaptive Architecture To Examine The Relationship Between Alexithymia And Interoception, Haneen Abdulhamid, Nils Jäger, Holger Schnädelbach, Alastair D. Smith
Room To Breathe: Using Adaptive Architecture To Examine The Relationship Between Alexithymia And Interoception, Haneen Abdulhamid, Nils Jäger, Holger Schnädelbach, Alastair D. Smith
School of Psychology
ObjectiveIndividuals with alexithymia experience difficulties interpreting emotional states in self and others, which has been associated with interoceptive impairment. Current theories are primarily based on subjective and conscious measures of interoceptive sensitivity, such as heartrate detection, but it is unclear whether similar observations would be found for objective or implicit psychophysiological measures. The present exploratory study assesses the potential of a novel assay through the use of adaptive immersive architecture [ExoBuilding].MethodsN = 88 participants were screened for alexithymic traits and N = 27 individuals, representing the range of scores, were sampled to participate in the behavioural task. In a repeated-measures …
The Application Of Precaution In Elasmobranch Conservation And Management In The Mediterranean Sea, Lydia Koehler, Ioannis Giovos, Jason Lowther
The Application Of Precaution In Elasmobranch Conservation And Management In The Mediterranean Sea, Lydia Koehler, Ioannis Giovos, Jason Lowther
School of Law, Humanities and Social Sciences
No abstract provided.
Citizen Science In Marine Litter Research: A Review, L. A. Kawabe, N. P. Ghilardi-Lopes, A. Turra, K. J. Wyles
Citizen Science In Marine Litter Research: A Review, L. A. Kawabe, N. P. Ghilardi-Lopes, A. Turra, K. J. Wyles
School of Psychology
No abstract provided.
Molecular Pathology: Potential Biomarkers For The Detection Of Down Syndrome Pregnancies, Raed Garout
Molecular Pathology: Potential Biomarkers For The Detection Of Down Syndrome Pregnancies, Raed Garout
School of Biomedical Sciences Theses
Down Syndrome (DS), also called trisomy 21, is the most common non- lethal fetal aneuploidy that affects 1 in 800 live births. The disease appears mostly due to the existence of an extra copy of chromosome 21. In the UK, the screening of DS is offered to all pregnant women in the antena- tal care program to assess the risk of DS. If the risk is high the women are offered further testing that includes invasive sampling (amniocente- sis or chorionic villus sampling) to confirm the diagnosis. This project aimed to investigate the possibility of applying new methods to screen …
Water Table Depth Modulates Productivity And Biomass Across Amazonian Forests, Thaiane R. Sousa, Juliana Schietti, Io Ribeiro, Thaise Emílio, Rafael Herrera Fernández, Steege H Ter, Carolina V. Castilho, A Esquivel‐Muelbert, Timothy Baker, A Pontes‐Lopes, Cvj Silva, Jm Silveira, Géraldine Derroire, Wendeson Castro, Am Mendoza, Ademir Ruschel, Adriana Prieto, Adriano José Nogueira Lima, Agustín Rudas, A Araujo‐Murakami, Alexander Parada Gutierrez, Ana Andrade, Anand Roopsind, Angelo Gilberto Manzatto, Fiore A Di, A Torres‐Lezama, Aurélie Dourdain, B Marimon, Bh Marimon, Benoit Burban
Water Table Depth Modulates Productivity And Biomass Across Amazonian Forests, Thaiane R. Sousa, Juliana Schietti, Io Ribeiro, Thaise Emílio, Rafael Herrera Fernández, Steege H Ter, Carolina V. Castilho, A Esquivel‐Muelbert, Timothy Baker, A Pontes‐Lopes, Cvj Silva, Jm Silveira, Géraldine Derroire, Wendeson Castro, Am Mendoza, Ademir Ruschel, Adriana Prieto, Adriano José Nogueira Lima, Agustín Rudas, A Araujo‐Murakami, Alexander Parada Gutierrez, Ana Andrade, Anand Roopsind, Angelo Gilberto Manzatto, Fiore A Di, A Torres‐Lezama, Aurélie Dourdain, B Marimon, Bh Marimon, Benoit Burban
School of Geography, Earth and Environmental Sciences
Aim: Water availability is the major driver of tropical forest structure and dynamics. Most research has focused on the impacts of climatic water availability, whereas remarkably little is known about the influence of water table depth and excess soil water on forest processes. Nevertheless, given that plants take up water from the soil, the impacts of climatic water supply on plants are likely to be modulated by soil water conditions. Location: Lowland Amazonian forests. Time period: 1971–2019. Methods: We used 344 long-term inventory plots distributed across Amazonia to analyse the effects of long-term climatic and edaphic water supply on forest …
An Exploration Of The Contribution Of Embodied, Situated Research Strategies To Cultural Ecosystem Services And Landscape Assessment Frameworks: An Environmental Empathy Case Study, Klara Łucznik, Joane V. Serrano, John Martin
An Exploration Of The Contribution Of Embodied, Situated Research Strategies To Cultural Ecosystem Services And Landscape Assessment Frameworks: An Environmental Empathy Case Study, Klara Łucznik, Joane V. Serrano, John Martin
Professional Services
Since the Millennium Ecosystem Assessment in 2005, interest has increased in cultural ecosystem services (CESs) research to understand the complexity of the non-material benefits that people obtain from ecosystems. The intangible and interactive characteris-tics of CESs present many challenges regarding how to approach, quantify and even de-fine CESs. In this paper, we suggest looking at CESs through the lens of embodied and situated cognition theories. We advocate that such an approach should be applied to the development stage of CES research projects, as the embodied and situated experience of the site aids the development of research questions and future interventions. …
Investigating ‘Active Citizenship’: A Journey Toward The Political Heart Of Education In The Company Of Hannah Arendt., Kevin Richard Walker
Investigating ‘Active Citizenship’: A Journey Toward The Political Heart Of Education In The Company Of Hannah Arendt., Kevin Richard Walker
Plymouth Institute of Education Theses
The formation of ‘active citizens’ has become a desirable educational outcome in mainstream secondary and adult education in the UK. However, there is a wide range of interpretations regarding what being ‘active’ as a citizen actually involves and a lack of consensus on the role of education in this process. Drawing on Arendt’s conception of action as the basis of political activity where “to be free and to act are the same” (Arendt 1968a: 153), I propose an understanding of ‘active citizenship’ which involves the appearance of an individual citizen in relationship with the shared public world. It is argued …
A Riverine Ecosystem Service Cascade Model (Rescam) Framework For Assessing Ecosystem Service Provision As Applied To English Geomorphic River Types, Claire Bithell
School of Geography, Earth and Environmental Sciences Theses
Riverine ecosystems are considered the lifeblood of the Earth and because of this, have been exploited for centuries for social, agricultural and industrial development, resulting in their environmental degradation and simplification. This has led to a shift in the natural processes and functions and thus their ability to provide a full range and overall high levels of regulating, provisioning and cultural ecosystem services, which humans rely on. An ecosystem service and nature-based approach is being increasingly recognised as a useful tool to help evaluate, protect and restore river ecosystems for maximising the delivery of ecosystem services sustainably. Riverine ecosystem services …
Adaptive Capacity And The Responses Of Local Governance Actors To Evolutionary Political-Economic Change: Lessons From The Heart Of The South West Local Enterprise Partnership, Tim Sydenham
School of Geography, Earth and Environmental Sciences Theses
This thesis critically examines how micro-level adaptive processes and capacities operate and unfold in local/regional economic development governance in the context of cumulative and often disruptive political-economic change. It argues that states often seek to promote the adaptability and growth of local/regional economies by reconfiguring subnational governance arrangements but the evolutionary consequences of centrally driven state transformation processes for local/regional adaptation remain unclear. Evolutionary economic geography (EEG) provides concepts, mechanisms and models of adaptation but has tended to focus on firms and macro-structural economic change and pay limited attention to how the critical micro-level adaptive processes at work are influenced …