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Editorial: The Dual-Use Dilemma For Biomimicry, Samar Damiati, Rami Mhanna, Shakil A. Awan, Rimantas Kodzius, Bernhard Schuster May 2022

Editorial: The Dual-Use Dilemma For Biomimicry, Samar Damiati, Rami Mhanna, Shakil A. Awan, Rimantas Kodzius, Bernhard Schuster

School of Engineering, Computing and Mathematics

The biomimetic fabrication of 3D biology models confers design freedom across various applications. Taking inspiration from nature and using nature as a toolbox have helped in the production of effective and versatile tools that are integrated with modern technology principles and, importantly, perform quite similarly to natural living systems. Exploiting nature’s design principles can contribute to the improvement of the understanding and development of creative products in both fundamental research and industrial applications (Dicks, 2016; Orapiriyakul et al., 2018; Damiati, 2020). To address the significant heterogeneity among bio-inspired designs, this research topic collected articles that reflect the progress in the …


Impacts Of Artificial Light At Night (Alan) In Marine Ecosystems – A Review, Laura F.B. Marangoni, Thomas Davies, Tim Smyth, R Airam, Mark Hamann, Cristian Duarte, Kellie Pendoley, Jørgen Berge, Elena Maggi, Oren Levy May 2022

Impacts Of Artificial Light At Night (Alan) In Marine Ecosystems – A Review, Laura F.B. Marangoni, Thomas Davies, Tim Smyth, R Airam, Mark Hamann, Cristian Duarte, Kellie Pendoley, Jørgen Berge, Elena Maggi, Oren Levy

School of Biological and Marine Sciences

The globally widespread adoption of Artificial Light at Night (ALAN) began in the mid-20th century. Yet, it is only in the last decade that a renewed research focus has emerged into its impacts on ecological and biological processes in the marine environment that are guided by natural intensities, moon phase, natural light and dark cycles and daily light spectra alterations. The field has diversified rapidly from one restricted to impacts on a handful of vertebrates, to one in which impacts have been quantified across a broad array of marine and coastal habitats and species. Here, we review the current understanding …


“A Fog That Impacts Everything”: A Qualitative Study Of Health-Related Quality Of Life In People Living With Hiv Who Have Cognitive Impairment, K Alford, S Daley, S Banerjee, Et Al May 2022

“A Fog That Impacts Everything”: A Qualitative Study Of Health-Related Quality Of Life In People Living With Hiv Who Have Cognitive Impairment, K Alford, S Daley, S Banerjee, Et Al

Peninsula Medical School

Background Cognitive impairment (CI) in people living with HIV (PLWH) is an important health concern in the context of an ageing HIV population. Impacting 14–28% of PLWH, CI is associated with lower health-related quality of life (HRQoL), however, evaluation of the illness-specific factors comprising HRQoL in PLWH with CI have not been assessed. Objective We sought to contribute evidence toward an understanding of HRQoL and identify domains of HRQoL in PLWH with CI. Methods Qualitative interviews with 25 PLWH with objective CI related to HIV disease were conducted with participants attending HIV clinics in the UK. Clinically significant CI was …


Unc45a Deficiency Causes Microvillus Inclusion Disease–Like Phenotype By Impairing Myosin Vb–Dependent Apical Trafficking, Rémi Duclaux-Loras, Corinne Lebreton, Jérémy Berthelet, Fabienne Charbit-Henrion, Ophelie Nicolle, De Courtils C Revenu, Stephanie Waich, Taras Valovka, Anis Khiat, Marion Rabant, Caroline Racine, Ida Chiara Guerrera, Júlia Baptista, Maxime M. Mahe, Michael W. Hess, Béatrice Durel, Nathalie Lefort, Céline Banal, Mélanie Parisot, Cecile Talbotec, Florence Lacaille, Emmanuelle Ecochard-Dugelay, Arzu Meltem Demir, Georg F. Vogel, Laurence Faivre, Astor Rodrigues, Darren Fowler, Andreas R. Janecke, Thomas Müller, Andreas R. Janecke, Fernando Rodrigues-Lima, Frank M. Ruemmele, Holm H. Uhlig, Bene F Del, Grégoire Michaux, Nadine Cerf-Bensussan, Marianna Parlato May 2022

Unc45a Deficiency Causes Microvillus Inclusion Disease–Like Phenotype By Impairing Myosin Vb–Dependent Apical Trafficking, Rémi Duclaux-Loras, Corinne Lebreton, Jérémy Berthelet, Fabienne Charbit-Henrion, Ophelie Nicolle, De Courtils C Revenu, Stephanie Waich, Taras Valovka, Anis Khiat, Marion Rabant, Caroline Racine, Ida Chiara Guerrera, Júlia Baptista, Maxime M. Mahe, Michael W. Hess, Béatrice Durel, Nathalie Lefort, Céline Banal, Mélanie Parisot, Cecile Talbotec, Florence Lacaille, Emmanuelle Ecochard-Dugelay, Arzu Meltem Demir, Georg F. Vogel, Laurence Faivre, Astor Rodrigues, Darren Fowler, Andreas R. Janecke, Thomas Müller, Andreas R. Janecke, Fernando Rodrigues-Lima, Frank M. Ruemmele, Holm H. Uhlig, Bene F Del, Grégoire Michaux, Nadine Cerf-Bensussan, Marianna Parlato

Peninsula Medical School

No abstract provided.


The Effect Of The Covid-19 Pandemic On Severe Asthma Care In Europe - Will Care Change For Good?, Alison Bacon May 2022

The Effect Of The Covid-19 Pandemic On Severe Asthma Care In Europe - Will Care Change For Good?, Alison Bacon

School of Psychology

No abstract provided.


Single Extreme Storm Sequence Can Offset Decades Of Shoreline Retreat Projected To Result From Sea-Level Rise, Mitchell D. Harley, Gerd Masselink, De Alegría-Arzaburu A Ruiz, Nieves G. Valiente, Tim Scott May 2022

Single Extreme Storm Sequence Can Offset Decades Of Shoreline Retreat Projected To Result From Sea-Level Rise, Mitchell D. Harley, Gerd Masselink, De Alegría-Arzaburu A Ruiz, Nieves G. Valiente, Tim Scott

School of Biological and Marine Sciences

AbstractExtreme storms cause extensive beach-dune erosion and are typically considered to enhance coastal erosion due to sea-level rise. However, extreme storms can also have a positive contribution to the nearshore sediment budget by exchanging sediment between the lower and upper shoreface and/or between adjacent headlands, potentially mitigating some adverse sea-level rise impacts. Here we use three high-resolution morphological datasets of extreme storm-recovery sequences from Australia, the UK and Mexico to quantify the nearshore sediment budget and relate these episodic volume changes to long-term coastal projections. We show that sediment gains over the upper shoreface were large (59–140 m3/m) and sufficient …


Cryptic Lineages, Cryptic Barriers: Historical Seascapes And Oceanic Fronts Drive Genetic Diversity In Supralittoral Rockpool Beetles (Coleoptera: Hydraenidae), Adrián Villastrigo, David T. Bilton, P Abellan, A Millan, Ignacio Ribera, Josefa Velasco May 2022

Cryptic Lineages, Cryptic Barriers: Historical Seascapes And Oceanic Fronts Drive Genetic Diversity In Supralittoral Rockpool Beetles (Coleoptera: Hydraenidae), Adrián Villastrigo, David T. Bilton, P Abellan, A Millan, Ignacio Ribera, Josefa Velasco

School of Biological and Marine Sciences

No abstract provided.


Performing Resilience: Anchorage And Leverage In Live Action Role-Play Drama, Jamie Harper May 2022

Performing Resilience: Anchorage And Leverage In Live Action Role-Play Drama, Jamie Harper

School of Art, Design and Architecture

The concept of resilience is frequently described within neoliberal discourses as the ability of individuals to bounce back from shocks and reflexively adapt to changing circumstances. In ecological sciences, however, resilience is more commonly understood as the capacity of systems to radically transform themselves, when their usual mode of operation is challenged, rather than simply reverting to their original state. This article considers how live action role-play, as a form of participatory performance, might support ecological resilience by enabling players to actively reflect on their cultural practices in constructing the systems of their play and develop new capacities in the …


Filling Gaps Via Citizen Science: Phyllorhiza Punctata Von Lendenfeld, 1884 (Cnidaria: Scyphozoa: Mastigiidae) In Cyprus (Eastern Mediterranean Sea), A Kaminas, M Shokouros-Oskarsson, V Minasidis, J Langeneck, Et Al May 2022

Filling Gaps Via Citizen Science: Phyllorhiza Punctata Von Lendenfeld, 1884 (Cnidaria: Scyphozoa: Mastigiidae) In Cyprus (Eastern Mediterranean Sea), A Kaminas, M Shokouros-Oskarsson, V Minasidis, J Langeneck, Et Al

School of Biological and Marine Sciences

The Mediterranean Sea is one of the most heavily impacted areas by biological invasions worldwide, with over 650 non-indigenous species (NIS) reported as established in 2019. Information about the distribution of NIS in the basin is often fragmented or non-existent due to factors such as lack of finance, expertise, and appropriate surveillance systems. Citizen science might represent a reliable tool in monitoring the spread of NIS, being able to overcome the challenges of scientific monitoring. In the context of the citizen science project “Is it alien to you? Share it!!!”, we hereby first report the presence of the Australian spotted …


Quantum Brain Networks: A Perspective, Eduardo R. Miranda, José D. Martín-Guerrero, Satvik Venkatesh, Carlos Hernani-Morales, Lucas Lamata, Enrique Solano May 2022

Quantum Brain Networks: A Perspective, Eduardo R. Miranda, José D. Martín-Guerrero, Satvik Venkatesh, Carlos Hernani-Morales, Lucas Lamata, Enrique Solano

School of Art, Design and Architecture

We propose Quantum Brain Networks (QBraiNs) as a new interdisciplinary field integrating knowledge and methods from neurotechnology, artificial intelligence, and quantum computing. The objective is to develop an enhanced connectivity between the human brain and quantum computers for a variety of disruptive applications. We foresee the emergence of hybrid classical-quantum networks of wetware and hardware nodes, mediated by machine learning techniques and brain–machine interfaces. QBraiNs will harness and transform in unprecedented ways arts, science, technologies, and entrepreneurship, in particular activities related to medicine, Internet of Humans, intelligent devices, sensorial experience, gaming, Internet of Things, crypto trading, and business.


Two New High Andean Species Of Liodessus Diving Beetles From Venezuela (Coleoptera, Dytiscidae, Bidessini), Michael Balke, David T. Bilton, Mauricio García, Ángel L. Viloria, Adrián Villastrigo, Lars Hendrich May 2022

Two New High Andean Species Of Liodessus Diving Beetles From Venezuela (Coleoptera, Dytiscidae, Bidessini), Michael Balke, David T. Bilton, Mauricio García, Ángel L. Viloria, Adrián Villastrigo, Lars Hendrich

School of Biological and Marine Sciences

Two new species of the diving beetle genus Liodessus Guignot, 1939 are described from high mountain regions in Venezuela: Liodessus meridensissp. nov. from Laguna de Mucabají, Mérida and L. venezuelensissp. nov. from Laguna de Mucabají and below Pico Bolívar, Mérida. We delineate the species using morphological characters such as male genital structure and beetle size, shape and color. Mitochondrial cox1 sequence data provided an additional character source. Both new species occur at altitudes above 3,500 m and were collected in shallow water at the edge of high-altitude ponds.


The Relationship Between Processing Speed And Verbal And Non-Verbal New Learning And Memory In Progressive Multiple Sclerosis, Nancy D. Chiaravalloti, John Deluca, Amber Salter, Maria Pia Amato, Giampaolo Brichetto, Jeremy Chataway, Ulrik Dalgas, Rachel Farrell, Peter Feys, Massimo Filippi, Jennifer Freeman, Matilde Inglese, Cecilia Meza, Nancy B. Moore, Robert W. Motl, Maria Assunta Rocca, Brian M. Sandroff, Gary Cutter, Anthony Feinstein May 2022

The Relationship Between Processing Speed And Verbal And Non-Verbal New Learning And Memory In Progressive Multiple Sclerosis, Nancy D. Chiaravalloti, John Deluca, Amber Salter, Maria Pia Amato, Giampaolo Brichetto, Jeremy Chataway, Ulrik Dalgas, Rachel Farrell, Peter Feys, Massimo Filippi, Jennifer Freeman, Matilde Inglese, Cecilia Meza, Nancy B. Moore, Robert W. Motl, Maria Assunta Rocca, Brian M. Sandroff, Gary Cutter, Anthony Feinstein

School of Health Professions

Objective: Processing speed (PS) deficits are the most common cognitive deficits in multiple sclerosis (MS), followed by learning and memory deficits, and are often an early cognitive problem. It has been argued that impaired PS is a primary consequence of MS, which in turn decreases learning. The current analysis examined the association between PS and learning in a large cohort of individuals with progressive MS. Methods: Baseline data from a randomized clinical trial on rehabilitation taking place at 11 centers across North America and Europe were analyzed. Participants included 275 individuals with clinically definite progressive MS (primary, secondary) consented into …


Assessing Reactive Violence Using Immersive Virtual Reality, Sylvia Terbeck, Alison Bacon, I Howard May 2022

Assessing Reactive Violence Using Immersive Virtual Reality, Sylvia Terbeck, Alison Bacon, I Howard

School of Psychology

No abstract provided.


Recessive Prdm13 Mutations Cause Fatal Perinatal Brainstem Dysfunction With Cerebellar Hypoplasia And Disrupt Purkinje Cells Differentiation, Marion Coolen, Nami Altin, Karthyayani Rajamani, Eva Pereira, Karine Siquier-Pernet, Lombardi E Puig, Nadjeda Moreno, Giulia Barcia, Marianne Yvert, Annie Laquerrière, Aurore Pouliet, Patrick Nitschké, Nathalie Boddaert, Antonio Rausell, Féréchté Razavi, Alexandra Afenjar, De Villemeur T Billette, Almundher Al-Maawali, Khalid Al-Thihli, Julia Baptista, Ana Beleza-Meireles, Catherine Garel, Marine Legendre, Antoinette Gelot, Lydie Burglen, Sébastien Moutton, Vincent Cantagrel May 2022

Recessive Prdm13 Mutations Cause Fatal Perinatal Brainstem Dysfunction With Cerebellar Hypoplasia And Disrupt Purkinje Cells Differentiation, Marion Coolen, Nami Altin, Karthyayani Rajamani, Eva Pereira, Karine Siquier-Pernet, Lombardi E Puig, Nadjeda Moreno, Giulia Barcia, Marianne Yvert, Annie Laquerrière, Aurore Pouliet, Patrick Nitschké, Nathalie Boddaert, Antonio Rausell, Féréchté Razavi, Alexandra Afenjar, De Villemeur T Billette, Almundher Al-Maawali, Khalid Al-Thihli, Julia Baptista, Ana Beleza-Meireles, Catherine Garel, Marine Legendre, Antoinette Gelot, Lydie Burglen, Sébastien Moutton, Vincent Cantagrel

Peninsula Medical School

No abstract provided.


Male Song Stability Shows Cross‐Year Repeatability But Does Not Affect Reproductive Success In A Wild Passerine Bird, Alexander Hutfluss, E Bermúdez‐Cuamatzin, Alexia Mouchet, Mark Briffa, Hans Slabbekoorn, Niels J. Dingemanse May 2022

Male Song Stability Shows Cross‐Year Repeatability But Does Not Affect Reproductive Success In A Wild Passerine Bird, Alexander Hutfluss, E Bermúdez‐Cuamatzin, Alexia Mouchet, Mark Briffa, Hans Slabbekoorn, Niels J. Dingemanse

School of Biological and Marine Sciences

No abstract provided.


Young‐Onset Colorectal Cancer: Insights From An English Population‐Based Study, Joshua Franklyn, Joe Lomax, Peter L.Z. Labib, Amy Baker, Supriya Balasubramanya, Joe Natale, Muhammad Abdalkoddus, Joanne Hosking, Mark G. Coleman, Sebastian Smolarek May 2022

Young‐Onset Colorectal Cancer: Insights From An English Population‐Based Study, Joshua Franklyn, Joe Lomax, Peter L.Z. Labib, Amy Baker, Supriya Balasubramanya, Joe Natale, Muhammad Abdalkoddus, Joanne Hosking, Mark G. Coleman, Sebastian Smolarek

Peninsula Medical School

No abstract provided.


Aptamer Functionalized Zno Thin-Film Transistor Based Multiplexed Detection Of Lead And E. Coli In Water, Sk Honnali, Vs Ragha, R Ashwath, G Saravanavel, Kr Gunasekhar, S Sambandan, Ss Gorthi, B O’Driscoll, D Jenkins May 2022

Aptamer Functionalized Zno Thin-Film Transistor Based Multiplexed Detection Of Lead And E. Coli In Water, Sk Honnali, Vs Ragha, R Ashwath, G Saravanavel, Kr Gunasekhar, S Sambandan, Ss Gorthi, B O’Driscoll, D Jenkins

School of Engineering, Computing and Mathematics

No abstract provided.


Conducting Randomized Controlled Trials Of Complex Interventions In Prisons: A Sisyphean Task?, Charlotte Lennox, Sarah Leonard, Jane Senior, Caroline Hendricks, Sarah Rybczynska-Bunt, Cath Quinn, Richard Byng, Jenny Shaw May 2022

Conducting Randomized Controlled Trials Of Complex Interventions In Prisons: A Sisyphean Task?, Charlotte Lennox, Sarah Leonard, Jane Senior, Caroline Hendricks, Sarah Rybczynska-Bunt, Cath Quinn, Richard Byng, Jenny Shaw

Peninsula Medical School

Randomized Controlled Trials (RCT) are the “gold standard” for measuring the effectiveness of an intervention. However, they have their limitations and are especially complex in prison settings. Several systematic reviews have highlighted some of the issues, including, institutional constraints e.g., “lock-downs,” follow-ups, contamination of allocation conditions and a reliance on self-report measures. In this article, we reflect on our experiences and will describe two RCTs. People in prison are a significantly disadvantaged and vulnerable group, ensuring equitable and effective interventions is key to reducing inequality and promoting positive outcomes. We ask are RCTs of complex interventions in prisons a sisyphean …


A Cohort Study Of The Impact Of Covid‐19 On The Quality Of Life Of People Newly Diagnosed With Dementia And Their Family Carers, B Hicks, S Read, B Hu, S Banerjee, Et Al May 2022

A Cohort Study Of The Impact Of Covid‐19 On The Quality Of Life Of People Newly Diagnosed With Dementia And Their Family Carers, B Hicks, S Read, B Hu, S Banerjee, Et Al

Peninsula Medical School

Introduction COVID-19 has impacted people with dementia and their family carers, yet little is known about effects on overall quality of life. Methods In a UK cohort study, pre- and post-pandemic data were collected from 114 carers and 93 recently diagnosed people with dementia. Latent growth curve modeling examined change in quality of life. Results Carers reported significant decline in quality of life, although no change was demonstrated by people with dementia. In multivariable analyses, higher levels of cognitive impairment, deprivation, study site, and lower number of memory clinic contacts were associated with greater decline in carer quality of life. …


Uk State Identity-Making And British Overseas Territories’ Environments In Times Of Ecological Crisis And Geopolitical Change, N Harmer, I Bailey, N Hart May 2022

Uk State Identity-Making And British Overseas Territories’ Environments In Times Of Ecological Crisis And Geopolitical Change, N Harmer, I Bailey, N Hart

School of Geography, Earth and Environmental Sciences

Analysis of state identity constructions can provide important insights into the ideologies, values, ambitions and policies of influential state actors. Existing research on state identities has focused mainly on how such identities are constructed and utilised within domestic politics or conventional inter-state/international relations but limited attention has been paid to how states construct their identities in relation to, and through, overseas territories that occupy liminal positions of sovereignty. This article addresses this gap by investigating how state actors have discursively constructed the UK’s identities through the lens of environmental protection in the UK’s overseas territories. It analyses UK parliamentary debate …


Learning From Natural Sediments To Tackle Microplastics Challenges: A Multidisciplinary Perspective, K Waldschläger, Mzm Brückner, B Carney Almroth, Et Al May 2022

Learning From Natural Sediments To Tackle Microplastics Challenges: A Multidisciplinary Perspective, K Waldschläger, Mzm Brückner, B Carney Almroth, Et Al

School of Biological and Marine Sciences

Although the study of microplastics in the aquatic environment incorporates a diversity of research fields, it is still in its infancy in many aspects while comparable topics have been studied in other disciplines for decades. In particular, extensive research in sedimentology can provide valuable insights to guide future microplastics research. To advance our understanding of the comparability of natural sediments with microplastics, we take an interdisciplinary look at the existing literature describing particle properties, transport processes, sampling techniques and ecotoxicology. Based on our analysis, we define seven research goals that are essential to improve our understanding of microplastics and can …


“Boom‐And‐Busted‐Dynamics” Of Phytoplankton‐Virus Interactions Explain The Paradox Of The Plankton, Kevin J. Flynn, Aditee Mitra, William H. Wilson, Susan A. Kimmance, Darren R. Clark, Angela Pelusi, Luca Polimene May 2022

“Boom‐And‐Busted‐Dynamics” Of Phytoplankton‐Virus Interactions Explain The Paradox Of The Plankton, Kevin J. Flynn, Aditee Mitra, William H. Wilson, Susan A. Kimmance, Darren R. Clark, Angela Pelusi, Luca Polimene

School of Biological and Marine Sciences

SummaryRapid virus proliferation can exert a powerful control on phytoplankton host populations, playing a significant role in marine biogeochemistry and ecology. We explore how marine lytic viruses impact phytoplankton succession, affecting host and nonhost populations.Using an in silico food web we conducted simulation experiments under a range of different abiotic and biotic conditions, exploring virus–host–grazer interactions and manipulating competition, allometry, motility and cyst cycles.Virus-host and predator–prey interactions, and interactions with competitors, generate bloom dynamics with a pronounced ‘boom-and-busted’ dynamic (BBeD) which leads to the suppression of otherwise potentially successful phytoplankton species. The BBeD is less pronounced at low nutrient loading …


Patient-To-Patient Interactions During The Pain Management Programme: The Role Of Humor And Venting In Building A Socially Supportive Community, Krithika Anil Apr 2022

Patient-To-Patient Interactions During The Pain Management Programme: The Role Of Humor And Venting In Building A Socially Supportive Community, Krithika Anil

School of Health Professions

No abstract provided.


Future Climate Change Conditions May Compromise Metabolic Performance In Juveniles Of The Mud Crab Scylla Serrata, Elina Apine, Madhu K. Mani, Praveen Rai, Indrani Karunasagar, Lucy M. Turner Apr 2022

Future Climate Change Conditions May Compromise Metabolic Performance In Juveniles Of The Mud Crab Scylla Serrata, Elina Apine, Madhu K. Mani, Praveen Rai, Indrani Karunasagar, Lucy M. Turner

School of Biological and Marine Sciences

Research characterising the effects of future climate change on the marine environment remains heavily focussed on that of temperate regions and organisms. Furthermore, little is known of these effects on the early life stages of many marine species. Tropical regions are already experiencing an increase in sea surface temperature and decrease in sea surface salinity, conditions favoured by pathogenic bacteria such as Vibrio spp. The early life stages of crabs are known to be particularly vulnerable to both the direct physiological effects of climate change and exposure to harmful microorganisms, yet there are limited data on these effects on juveniles …


Evidence Of Former Sea Levels From A Passive Seismic Survey At A Sandy Beach; Perranporth, Sw England, Uk, Andres Payo, Gareth O. Jenkins, Dave Morgan, Nieves G. Valiente, Timothy Scott Apr 2022

Evidence Of Former Sea Levels From A Passive Seismic Survey At A Sandy Beach; Perranporth, Sw England, Uk, Andres Payo, Gareth O. Jenkins, Dave Morgan, Nieves G. Valiente, Timothy Scott

School of Biological and Marine Sciences

Since the end of the last glaciation, the United Kingdom’s land surface has been altered by isostatic rebound, rising in the north and sinking in the south. Numerous studies have been published documenting the impact of isostatic rebound on relative sea levels. However, due to the difficulties in acquiring evidence to prove former sea levels, locally, these data can be sparse or absent. In this work, we explored the suitability of the passive seismic survey (PSS) method to estimate the contemporaneous beach thickness in coastal environments where there is a high impedance contrast between the beach deposits and the underlying …


Lessons From The Western Atlantic Lionfish Invasion To Inform Management In The Mediterranean, Aylin Ulman, Fadilah Z. Ali, Holden E. Harris, Mohammad Adel, Sara A.A.Al Mabruk, Michel Bariche, Allison C. Candelmo, Jennifer K. Chapman, Burak Ali Çiçek, Kaylin R. Clements, Alexander Q. Fogg, Stacy Frank, Stephen R. Gittings, Stephanie J. Green, Jason M. Hall-Spencer, Jim Hart, Summer Huber, Philip E. Karp, Fabian C. Kyne, Demetris Kletou, Lauryn Magno, Shevy B.S. Rothman, Jennifer N. Solomon, Nir Stern, Taner Yildiz Apr 2022

Lessons From The Western Atlantic Lionfish Invasion To Inform Management In The Mediterranean, Aylin Ulman, Fadilah Z. Ali, Holden E. Harris, Mohammad Adel, Sara A.A.Al Mabruk, Michel Bariche, Allison C. Candelmo, Jennifer K. Chapman, Burak Ali Çiçek, Kaylin R. Clements, Alexander Q. Fogg, Stacy Frank, Stephen R. Gittings, Stephanie J. Green, Jason M. Hall-Spencer, Jim Hart, Summer Huber, Philip E. Karp, Fabian C. Kyne, Demetris Kletou, Lauryn Magno, Shevy B.S. Rothman, Jennifer N. Solomon, Nir Stern, Taner Yildiz

School of Biological and Marine Sciences

Major invasions of Indo-Pacific lionfish (Pterois volitans and P. miles) are underway in the Western Atlantic Ocean and the Mediterranean Sea. While the establishment of lionfish in the Western Atlantic is perhaps the most well-studied marine fish invasion to date, the rapidly expanding invasion in the Mediterranean is more recent and has received less attention. Here we review and synthesize successes and failures from two decades of lionfish management in the Western Atlantic to give policy recommendations for their management in the Mediterranean. Two failed approaches that were attempted multiple times in the Western Atlantic and that we advise against …


Biotic And Abiotic Degradation Of Suspended Particulate Lipids Along A Transect In The Chukchi Sea, Jean François Rontani, Lukas Smik, Sun Yong Ha, Jun Oh Min, Simon T. Belt Apr 2022

Biotic And Abiotic Degradation Of Suspended Particulate Lipids Along A Transect In The Chukchi Sea, Jean François Rontani, Lukas Smik, Sun Yong Ha, Jun Oh Min, Simon T. Belt

School of Geography, Earth and Environmental Sciences

No abstract provided.


A Roadmap To Doing Culturally Grounded Developmental Science, Tanya Broesch, Sheina Lew-Levy, Michelle Kline, Joscha Kärtner, Patricia Kanngiesser Apr 2022

A Roadmap To Doing Culturally Grounded Developmental Science, Tanya Broesch, Sheina Lew-Levy, Michelle Kline, Joscha Kärtner, Patricia Kanngiesser

School of Psychology

This paper provides a roadmap for engaging in cross-cultural, developmental research in practical, ethical, and community-engaged ways. To cultivate the flexibility necessary for conducting cross-cultural research, we structure our roadmap as a series of questions that each research program might consider prior to embarking on cross-cultural examinations in developmental science. Within each topic, we focus on the challenges and opportunities inherent to different types of study designs, fieldwork, and collaborations because our collective experience in conducting research in multiple cultural contexts has taught us that there can be no single “best practice”. Here we identify the challenges that are unique …


Challenges Of Incorporating Digital Health Technology Outcomes In A Clinical Trial: Experiences From Pd Stat, Jacob O. Day, Stephen Smith, Alastair J. Noyce, Jane Alty, Alison Jeffery, Rebecca Chapman, Camille Carroll Apr 2022

Challenges Of Incorporating Digital Health Technology Outcomes In A Clinical Trial: Experiences From Pd Stat, Jacob O. Day, Stephen Smith, Alastair J. Noyce, Jane Alty, Alison Jeffery, Rebecca Chapman, Camille Carroll

Peninsula Medical School

Digital health technologies (DHTs) have great potential for use as clinical trial outcomes; however, practical issues need to be addressed in order to maximise their benefit. We describe our experience of incorporating two DHTs as secondary/exploratory outcome measures in PD STAT, a randomised clinical trial of simvastatin in people with Parkinson’s disease. We found much higher rates of missing data in the DHTs than the traditional outcome measures, in particular due to technical and software difficulties. We discuss methods to address these obstacles in terms of protocol design, workforce training and data management.


Nfat Factors Are Dispensable For The Development But Are Critical For The Maintenance Of Foxp3+ Regulatory T Cells, De Brito C Barahona, Amiya Kumar Patra Apr 2022

Nfat Factors Are Dispensable For The Development But Are Critical For The Maintenance Of Foxp3+ Regulatory T Cells, De Brito C Barahona, Amiya Kumar Patra

Peninsula Medical School

The transcription factors of the nuclear factor of activated T cell (NFAT) family play a crucial role in multiple aspects of T cell function. It has recently been reported that NFATs play an important role in the suppressive function of CD4+CD25+Foxp3+ regulatory T (Treg) cells. In this study, we have investigated the role of NFATs in the thymic development of Treg cells in mice. We show that NFAT factors are dispensable for the development of Foxp3+ Treg cells in the thymus but are critical for the maintenance of both the phenotype and survival of Treg cells in the thymus as …