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Phenomics Enables Measurement Of Complex Responses Of Developing Animals To Global Environmental Drivers, Oliver Tills, Luke A. Holmes, Elliot Quinn, Tony Everett, Manuela Truebano, John I. Spicer Feb 2023

Phenomics Enables Measurement Of Complex Responses Of Developing Animals To Global Environmental Drivers, Oliver Tills, Luke A. Holmes, Elliot Quinn, Tony Everett, Manuela Truebano, John I. Spicer

School of Biological and Marine Sciences

Phenomics offers technological advances for high-dimensional phenotyping, facilitating rapid, high-throughput assessment of physiological performance and has proven invaluable in global research challenges including drug discovery and food security. However, this rapidly growing discipline has remained largely inaccessible to the increasingly urgent challenge of assessing organismal functional sensitivity to global change drivers. Here, we investigate the response of an ecologically important marine invertebrate to multiple environmental drivers using Energy Proxy Traits (EPTs), a new approach for measuring complex phenotypes captured on video as a spectrum of energy levels across different temporal frequencies in fluctuating pixel values. We imaged three developmental stages …


Shoreline Modelling On Timescales Of Days To Decades, Emily Hunt, Mark Davidson, Edward C. C. Steele, Jessica D. Amies, Timothy Scott, Paul Russell Feb 2023

Shoreline Modelling On Timescales Of Days To Decades, Emily Hunt, Mark Davidson, Edward C. C. Steele, Jessica D. Amies, Timothy Scott, Paul Russell

School of Biological and Marine Sciences

Climate change is resulting in global changes to sea level and wave climates,which in many locations significantly increasethe probability of erosion, floodingand damage to coastal infrastructure and ecosystems.Therefore, there isa pressing societal need to be able to forecast themorphological evolution of our coastlines over a broad range of timescales, spanningdays-to-decades, facilitating more focussed, appropriate,and cost-effective management interventions and data informed planning to support thedevelopment of coastal environments. A wide range of modelling approaches have been used with varying degrees of success to assess both the detailed morphological evolution and/or simplified indicators of coastal erosion/accretion.This paper presents an overview of these …


Applying Landscape Metrics To Species Distribution Model Predictions To Characterize Internal Range Structure And Associated Changes, A Curd, M Chevalier, M Vasquez, A Boyé, Et Al Feb 2023

Applying Landscape Metrics To Species Distribution Model Predictions To Characterize Internal Range Structure And Associated Changes, A Curd, M Chevalier, M Vasquez, A Boyé, Et Al

School of Biological and Marine Sciences

Distributional shifts in species ranges provide critical evidence of ecological responses to climate change. Assessments of climate-driven changes typically focus on broad-scale range shifts (e.g. poleward or upward), with ecological consequences at regional and local scales commonly overlooked. While these changes are informative for species presenting continuous geographic ranges, many species have discontinuous distributions—both natural (e.g. mountain or coastal species) or human-induced (e.g. species inhabiting fragmented landscapes)—where within-range changes can be significant. Here, we use an ecosystem engineer species (Sabellaria alveolata) with a naturally fragmented distribution as a case study to assess climate-driven changes in within-range occupancy across its entire …


Persistent Reshaping Of Cohesive Sediment Towards Stable Flocs By Turbulence, M Yu, X Yu, Aj Mehta, Aj Manning, F Khan, S Balachandar Jan 2023

Persistent Reshaping Of Cohesive Sediment Towards Stable Flocs By Turbulence, M Yu, X Yu, Aj Mehta, Aj Manning, F Khan, S Balachandar

School of Biological and Marine Sciences

AbstractCohesive sediment forms flocs of various sizes and structures in the natural turbulent environment. Understanding flocculation is critical in accurately predicting sediment transport and biogeochemical cycles. In addition to aggregation and breakup, turbulence also reshapes flocs toward more stable structures. An Eulerian–Lagrangian framework has been implemented to investigate the effect of turbulence on flocculation by capturing the time-evolution of individual flocs. We have identified two floc reshaping mechanisms, namely breakage-regrowth and restructuring by hydrodynamic drag. Surface erosion is found to be the primary breakup mechanism for strong flocs, while fragile flocs tend to split into fragments of similar sizes. Aggregation …


A Review Of Biodegradable Plastics From Multidisciplinary Perspectives, Winnie Courtene-Jones, Falco F De, Imogen E. Napper Jan 2023

A Review Of Biodegradable Plastics From Multidisciplinary Perspectives, Winnie Courtene-Jones, Falco F De, Imogen E. Napper

School of Biological and Marine Sciences

No abstract provided.


Practical Implementation Of The Comprehensive Geriatric Assessment To Optimise Care For Older Adults With Cancer, Patricia Schofield, Philip R. Debruyne Jan 2023

Practical Implementation Of The Comprehensive Geriatric Assessment To Optimise Care For Older Adults With Cancer, Patricia Schofield, Philip R. Debruyne

School of Nursing and Midwifery

Whilst cancer remains a very serious health problem at any stage, cancer combined with increasing age creates an even more challenging situation for health care providers. Age is the principal non-modifiable risk factor for all cancer types. There is a rising incidence of cancer among older adults worldwide. In Belgium, the highest incidence rate is situated in the 80–84 age group [1]. In 2020, 60% of women and 70% of men in Belgium were aged 65 years or older when diagnosed, an increase of 6% for both sexes compared to 2010 [1]. Older adults with cancer can be a vulnerable …


Examining The Release Of Synthetic Microfibres To The Environment Via Two Major Pathways: Atmospheric Deposition And Treated Wastewater Effluent, I. E. Napper, F. N.F. Parker-Jurd, S. L. Wright, R. C. Thompson Jan 2023

Examining The Release Of Synthetic Microfibres To The Environment Via Two Major Pathways: Atmospheric Deposition And Treated Wastewater Effluent, I. E. Napper, F. N.F. Parker-Jurd, S. L. Wright, R. C. Thompson

School of Biological and Marine Sciences

Research on the discharge of synthetic microfibres to aquatic environments has typically focused on laundering, where fibres can be discharged via wastewater effluent. However emerging research suggests that microfibres generated during the wear of textiles in normal use could present a major, additional, pathway for microfibre pollution to the environment. This study aimed to quantify and compare the quantities of microfibre entering the marine environment via both these pathways; wastewater discharge and atmospheric deposition. Areas of high and low population density were also evaluated. Samples were collected in and around two British cities (Bristol and Plymouth) both of which are …


Pelagic Connectivity Of European Sea Bass Between Spawning And Nursery Grounds, Jennifer A. Graham, Joseph W. Watson, García Lm García, K Bradley, R Bradley, Mary Brown, Benjamin J. Ciotti, Derek Goodwin, Richard D.M. Nash, William K. Roche, Ciara Wogerbauer, Kieran Hyder Jan 2023

Pelagic Connectivity Of European Sea Bass Between Spawning And Nursery Grounds, Jennifer A. Graham, Joseph W. Watson, García Lm García, K Bradley, R Bradley, Mary Brown, Benjamin J. Ciotti, Derek Goodwin, Richard D.M. Nash, William K. Roche, Ciara Wogerbauer, Kieran Hyder

School of Biological and Marine Sciences

The sea bass stock around the UK (northern stock) has declined rapidly over the past decade, likely due to a combination of both overfishing and low recruitment. Understanding mechanisms that drive the number of young reaching nursery grounds is important for explaining observed recruitment variability and therefore developing effective management strategies. An individual-based model (IBM) has been developed here to investigate factors affecting sea bass settlement on nursery grounds for the northern stock. Simulations considered seven years with varying environmental conditions and year class strength, and outputs were compared to empirical data from monitoring of nursery areas in the UK …


The Effect Of Led Light Spectra On The Growth, Yield And Nutritional Value Of Red And Green Lettuce (Lactuca Sativa), Abdullah A. Alrajhi, Abdulaziz S. Alsahli, Ibrahim M. Alhelal, Hail Z. Rihan, Michael P. Fuller, Abdullah A. Alsadon, Abdullah A. Ibrahim Jan 2023

The Effect Of Led Light Spectra On The Growth, Yield And Nutritional Value Of Red And Green Lettuce (Lactuca Sativa), Abdullah A. Alrajhi, Abdulaziz S. Alsahli, Ibrahim M. Alhelal, Hail Z. Rihan, Michael P. Fuller, Abdullah A. Alsadon, Abdullah A. Ibrahim

School of Biological and Marine Sciences

Controlled Environment Agriculture (CEA) is a method of increasing crop productivity per unit area of cultivated land by extending crop production into the vertical dimension and enabling year-round production. Light emitting diodes (LED) are frequently used as the source of light energy in CEA systems and light is commonly the limiting factor for production under CEA conditions. In the current study, the impact of different spectra was compared with the use of white LED light. The various spectra were white; white supplemented with ultraviolet b for a week before harvest; three combinations of red/blue lights (red 660 nm with blue …


Workers’ Opinions On Using The Internet Of Things To Enhance The Performance Of The Olive Oil Industry: A Machine Learning Approach, Ahmed Alsayat, Hossein Ahmadi Jan 2023

Workers’ Opinions On Using The Internet Of Things To Enhance The Performance Of The Olive Oil Industry: A Machine Learning Approach, Ahmed Alsayat, Hossein Ahmadi

School of Nursing and Midwifery

Today’s global food supply chains are highly dispersed and complex. The adoption and effective utilization of information technology are likely to increase the efficiency of companies. Because of the broad variety of sensors that are currently accessible, the possibilities for Internet of Things (IoT) applications in the olive oil industry are almost limitless. Although previous studies have investigated the impact of the IoT on the performance of industries, this issue has yet to be explored in the olive oil industry. In this study we aimed to develop a new model to investigate the factors influencing supply chain improvement in olive …


Abiotic Stress Experiments Need A Reality Check To Improve Translation To The Field, Anne Plessis Jan 2023

Abiotic Stress Experiments Need A Reality Check To Improve Translation To The Field, Anne Plessis

School of Biological and Marine Sciences

No abstract provided.


Corrigendum: The Presence Of Silver Nanoparticles Reduces Demand For Dissolved Phosphorus To The Benefit Of Biological Nitrogen Fixation In The Coastal Eastern Mediterranean Sea, Ap Rees, E Faraggiana, K Tait, M Celussi, E Dafnomilli, V Manna, A Manning, P Pitta, A Tsiola, S Živanović Jan 2023

Corrigendum: The Presence Of Silver Nanoparticles Reduces Demand For Dissolved Phosphorus To The Benefit Of Biological Nitrogen Fixation In The Coastal Eastern Mediterranean Sea, Ap Rees, E Faraggiana, K Tait, M Celussi, E Dafnomilli, V Manna, A Manning, P Pitta, A Tsiola, S Živanović

School of Biological and Marine Sciences

No abstract provided.


Subunit Vaccine Targeting Phosphate Abc Transporter Atp-Binding Protein, Pstb, Provides Cross-Protection Against Streptococcus Suis Serotype 2, 7, And 9 In Mice, Zujie Yan, Xiaohui Yao, Ruyi Pan, Junjie Zhang, X Ma, Nihua Dong, Jianchao Wei, K Liu, Yafeng Qiu, Katie Sealey, Hester Nichols, Michael A. Jarvis, Mathew Upton, Xiangdong Li, Z Ma, J Liu, B Li Jan 2023

Subunit Vaccine Targeting Phosphate Abc Transporter Atp-Binding Protein, Pstb, Provides Cross-Protection Against Streptococcus Suis Serotype 2, 7, And 9 In Mice, Zujie Yan, Xiaohui Yao, Ruyi Pan, Junjie Zhang, X Ma, Nihua Dong, Jianchao Wei, K Liu, Yafeng Qiu, Katie Sealey, Hester Nichols, Michael A. Jarvis, Mathew Upton, Xiangdong Li, Z Ma, J Liu, B Li

School of Biomedical Sciences

Streptococcus suis is a significant pathogen in pigs and a newly emerging zoonotic agent in humans. The presence of multiple serotypes and strains with diversified sequence types in pig herds highlights the need for the identification of broadly cross-reactive universal vaccine antigen targets, capable of providing cross-protection against S. suis infection. Subunit vaccines based on the conserved proteins shared between different S. suis serotypes are potential candidates for such a universally protective vaccine. In the present study, phosphate ABC transporter ATP-binding protein PstB (PstB), an immunogenic protein of the S. suis bacterium, was expressed and purified, and then subjected to …


Subunit Vaccine Targeting Phosphate Abc Transporter Atp-Binding Protein, Pstb, Provides Cross-Protection Against Streptococcus Suis Serotype 2, 7, And 9 In Mice, Zujie Yan, Xiaohui Yao, Ruyi Pan, Junjie Zhang, X Ma, Nihua Dong, Jianchao Wei, K Liu, Yafeng Qiu, Katie Sealey, Hester Nichols, Michael A. Jarvis, Mathew Upton, X Li, Z Ma, J Liu, B Li Jan 2023

Subunit Vaccine Targeting Phosphate Abc Transporter Atp-Binding Protein, Pstb, Provides Cross-Protection Against Streptococcus Suis Serotype 2, 7, And 9 In Mice, Zujie Yan, Xiaohui Yao, Ruyi Pan, Junjie Zhang, X Ma, Nihua Dong, Jianchao Wei, K Liu, Yafeng Qiu, Katie Sealey, Hester Nichols, Michael A. Jarvis, Mathew Upton, X Li, Z Ma, J Liu, B Li

School of Biomedical Sciences

Streptococcus suis is a significant pathogen in pigs and a newly emerging zoonotic agent in humans. The presence of multiple serotypes and strains with diversified sequence types in pig herds highlights the need for the identification of broadly cross-reactive universal vaccine antigen targets, capable of providing cross-protection against S. suis infection. Subunit vaccines based on the conserved proteins shared between different S. suis serotypes are potential candidates for such a universally protective vaccine. In the present study, phosphate ABC transporter ATP-binding protein PstB (PstB), an immunogenic protein of the S. suis bacterium, was expressed and purified, and then subjected to …


Creating Equitable And Sustainable Opportunities For Nature Immersion To Support Restoration From Stress Within Mental Health Nursing: A Critical Interpretive Synthesis, Sarah Howes, Paul Warwick Jan 2023

Creating Equitable And Sustainable Opportunities For Nature Immersion To Support Restoration From Stress Within Mental Health Nursing: A Critical Interpretive Synthesis, Sarah Howes, Paul Warwick

School of Nursing and Midwifery

In the face of global environmental changes threatening health, and despite increased calls for nurses to broker access to nature-based well-being interventions for people with mental health difficulties, there is a surprising absence of literature examining the nature–nursing relationship, inhibiting its inclusion within nursing curricula and practice. This critical interpretive synthesis supports the notion that nature immersion has the capacity to increase positive affect, reduce negative affect, provide restoration from everyday stress, promote meaning-making, enhance belonging, and foster an interest in caring for the natural world. Yet, critical examination of the literature reveals multiple social and environmental inequalities and unmasks …


Synoptic Observations Of Sediment Transport And Exchange Mechanisms In The Turbid Ems Estuary: The Edom Campaign, Maren Ds Van, C Maushake, J-W Mol, Keulen D Van, J Jürges, J Vroom, H Schuttelaars, T Gerkema, K Schulz, Th Badewien, M Gerriets, A Engels, A Wurpts, D Oberrecht, Aj Manning, T Bailey, L Ross, V Mohrholz, Dml Horemans, M Becker, D Post, C Schmidt, Pjt Dankers Jan 2023

Synoptic Observations Of Sediment Transport And Exchange Mechanisms In The Turbid Ems Estuary: The Edom Campaign, Maren Ds Van, C Maushake, J-W Mol, Keulen D Van, J Jürges, J Vroom, H Schuttelaars, T Gerkema, K Schulz, Th Badewien, M Gerriets, A Engels, A Wurpts, D Oberrecht, Aj Manning, T Bailey, L Ross, V Mohrholz, Dml Horemans, M Becker, D Post, C Schmidt, Pjt Dankers

School of Biological and Marine Sciences

Abstract. An extensive field campaign, the Ems-Dollard Measurements (EDoM), was executed in the Ems Estuary, bordering the Netherlands and Germany, aimed at better understanding the mechanisms that drive the exchange of water and sediments between a relatively exposed outer estuary and a hyper-turbid tidal river. More specifically, the reasons for the large up-estuary sediment accumulation rates and the role of the tidal river on the turbidity in the outer estuary were insufficiently understood. The campaign was designed to unravel the hydrodynamic and sedimentary exchange mechanisms, comprising two hydrographic surveys during contrasting environmental conditions using eight concurrently operating ships and 10 …


Supracrestal Tissue Attachment: An Update, Jaini Shah, Leah Webb, Ewen Mccoll, Michael Daldry, Serena Bhagi, Rob Witton Jan 2023

Supracrestal Tissue Attachment: An Update, Jaini Shah, Leah Webb, Ewen Mccoll, Michael Daldry, Serena Bhagi, Rob Witton

Peninsula Dental School

Supracrestal tissue attachment (STA) is a relatively new term that was introduced in 2017 following the World Workshop on the Classification of Periodontal and Peri-implant Diseases and Conditions, co-sponsored by the American Academy of Periodontology (AAP) and the European Federation of Periodontology (EFP), which included expert participants from all over the world. It has replaced the term biological width, and refers to the junctional epithelium and supracrestal connective tissue. This article provides an updated review of the anatomy of STA, highlights the negative effects of violation and discusses its clinical relevance in restorative dentistry, including the use of crown lengthening. …


Testing Scores For Performing Placestories, Phil Smith Jan 2023

Testing Scores For Performing Placestories, Phil Smith

School of Art, Design and Architecture

This paper describes an experimental project conducted by artists/researchers Crab & Bee (Helen Billinghurst and Phil Smith). The project was put together in response to the Covid Lockdown restrictions during 2020 in the UK and drew upon an art and performance practice that had been unfolding since 2018. ‘Testing Scores for Performing Placestories’ describes the testing of a group of scores (with accompanying avatars, gameboards, narratives and images) for participants to perform in their own homes, for their effectivesss (or lack of it) in encouraging participants to make displaced performances by ‘fictioning’ with unhuman agents. The scores were based on …


Artificial Reefs Built By 3d Printing: Systematisation In The Design, Material Selection And Fabrication, Adrian I. Yoris-Nobile, Carlos J. Slebi-Acevedo, Esther Lizasoain-Arteaga, Irune Indacoechea-Vega, Elena Blanco-Fernandez, Daniel Castro-Fresno, Alejandro Alonso-Estebanez, Sara Alonso-Cañon, Carlos Real-Gutierrez, Fouad Boukhelf, Mohamed Boutouil, Nassim Sebaibi, Alice Hall, Sam Greenhill, Roger Herbert, Richard Stafford, Bianca Reis, Der Linden P Van, Oscar Babé Gómez, Hugo Sainz Meyer, João N. Franco, Emanuel Almada, Maria Teresa Borges, Isabel Sousa-Pinto, Miriam Tuaty-Guerra, Jorge Lobo-Arteaga Jan 2023

Artificial Reefs Built By 3d Printing: Systematisation In The Design, Material Selection And Fabrication, Adrian I. Yoris-Nobile, Carlos J. Slebi-Acevedo, Esther Lizasoain-Arteaga, Irune Indacoechea-Vega, Elena Blanco-Fernandez, Daniel Castro-Fresno, Alejandro Alonso-Estebanez, Sara Alonso-Cañon, Carlos Real-Gutierrez, Fouad Boukhelf, Mohamed Boutouil, Nassim Sebaibi, Alice Hall, Sam Greenhill, Roger Herbert, Richard Stafford, Bianca Reis, Der Linden P Van, Oscar Babé Gómez, Hugo Sainz Meyer, João N. Franco, Emanuel Almada, Maria Teresa Borges, Isabel Sousa-Pinto, Miriam Tuaty-Guerra, Jorge Lobo-Arteaga

School of Biological and Marine Sciences

The recovery of degraded marine coasts and the improvement of natural habitats are current issues of vital importance for the development of life, both marine and terrestrial. In this sense, the immersion of artificial reefs (ARs) in the marine environment is a way to stimulate the recovery of these damaged ecosystems. But it is necessary to have a multidisciplinary approach that analyses the materials, designs and construction process of artificial reefs in order to understand their true impact on the environment. For this reason, this paper presents the manufacture of artificial reefs by 3D printing, proposing designs with a combination …


Learning And Planning For Autonomous Systems With Emergent Hierarchical Representations And Decaying Short-Term Memory, Piotr Aleksander Bogdan Jan 2023

Learning And Planning For Autonomous Systems With Emergent Hierarchical Representations And Decaying Short-Term Memory, Piotr Aleksander Bogdan

School of Engineering, Computing and Mathematics Theses

How do we create machines with the ability to capture, record and recall memories of past experience? How should these machines choose the most optimal action based on those stored memories? These seem like crucial questions for creating intelligent machines capable of learning from experience. The field of Artificial Intelligence (AI) is trying to reproduce such capabilities with increasing success. Currently a large portion of AI algorithms are focusing on making decisions based on big sets of learned past experience examples in the form of instantaneous input-output mapping. They operate as discrete models where time is collapsed into independent signal …


Whose Morals, Exactly? A Critical Evaluation Of The Uk Law Of Obscenity Through A Human Rights Lens, Jake Aston Jan 2023

Whose Morals, Exactly? A Critical Evaluation Of The Uk Law Of Obscenity Through A Human Rights Lens, Jake Aston

Plymouth Law Review

No abstract provided.


Investigating The Genomic Distribution And Potential Contribution Of Retrotransposable Elements In Relation To Their Potential Impact On Genome Function And Predisposition To Human Diseases., Randa Aweis Ali Jan 2023

Investigating The Genomic Distribution And Potential Contribution Of Retrotransposable Elements In Relation To Their Potential Impact On Genome Function And Predisposition To Human Diseases., Randa Aweis Ali

School of Biomedical Sciences Theses

Abstract Investigating the genomic distribution and potential contribution of retrotransposable elements in relation to their potential impact on genome function and predisposition to human diseases. Randa Aweis Ali Active retrotransposable elements (RTEs) provide a continuous source of genomic diversity in humans. The potential impact of a novel RTE insertion depends on its genomic location. Previous studies investigating the landscape of polymorphic RTEs report their higher fraction in functional regions compared with fixed elements, thereby highlighting the potential impact of RTE activity on genome function (GF). However, studies have only recently begun incorporating RTE variants (RTEV) in association with complex human …


The Chicken That Sat Me Down:A Reflection Of My Journey Into Law, Chloe Giacalone Jan 2023

The Chicken That Sat Me Down:A Reflection Of My Journey Into Law, Chloe Giacalone

Plymouth Law Review

No abstract provided.


Abnormal Thalamic Functional Connectivity Correlates With Cardiorespiratory Fitness And Physical Activity In Progressive Multiple Sclerosis, Francesco Romanò, Robert W. Motl, Paola Valsasina, Maria Pia Amato, Giampaolo Brichetto, Nicolò Bruschi, Jeremy Chataway, Nancy D. Chiaravalloti, Gary Cutter, Ulrik Dalgas, John Deluca, Rachel Farrell, Peter Feys, Jennifer Freeman, Matilde Inglese, Cecilia Meza, Amber Salter, Brian M. Sandroff, Anthony Feinstein, Maria A. Rocca, Massimo Filippi Jan 2023

Abnormal Thalamic Functional Connectivity Correlates With Cardiorespiratory Fitness And Physical Activity In Progressive Multiple Sclerosis, Francesco Romanò, Robert W. Motl, Paola Valsasina, Maria Pia Amato, Giampaolo Brichetto, Nicolò Bruschi, Jeremy Chataway, Nancy D. Chiaravalloti, Gary Cutter, Ulrik Dalgas, John Deluca, Rachel Farrell, Peter Feys, Jennifer Freeman, Matilde Inglese, Cecilia Meza, Amber Salter, Brian M. Sandroff, Anthony Feinstein, Maria A. Rocca, Massimo Filippi

School of Health Professions

BackgroundAltered thalamic volumes and resting state (RS) functional connectivity (FC) might be associated with physical activity (PA) and cardiorespiratory fitness (CRF) in people with progressive multiple sclerosis (PMS).ObjectivesTo assess thalamic structural and functional alterations and investigate their correlations with PA/CRF levels in people with PMS.MethodsSeven-day accelerometry and cardiopulmonary exercise testing were used to assess PA/CRF levels in 91 persons with PMS. They underwent 3.0 T structural and RS fMRI acquisition with 37 age/sex-matched healthy controls (HC). Between-group comparisons of MRI measures and their correlations with PA/CRF variables were assessed.ResultsPMS people had lower volumes compared to HC (all p < 0.001). At corrected threshold, PMS showed decreased intra- and inter-thalamic RS FC, and increased RS FC between the thalamus and the hippocampus, bilaterally. At uncorrected threshold, decreased thalamic RS FC with caudate nucleus, cerebellum and anterior cingulate cortex (ACC), as well as increased thalamic RS FC with occipital regions, were also detected. Lower CRF, measured as peak oxygen consumption (VO2peak), correlated with lower white matter volume (r = 0.31, p = 0.03). Moreover, lower levels of light PA correlated with increased thalamic RS FC with the right hippocampus (r = − 0.3, p = 0.05).DiscussionPeople with PMS showed widespread brain atrophy, as well as pronounced intra-thalamic and thalamo-hippocampal RS FC abnormalities. White matter atrophy correlated with CRF, while increased thalamo-hippocampal RS FC was associated to worse PA levels. Thalamic RS FC might be used to monitor physical impairment and efficacy of rehabilitative and disease-modifying treatments in future studies.


“I Certainly Didn’T Expect The Spanish Inquisition!”: Politics Of Transculturation In A Spanish Enclave In North Africa, Brian Campbell, Brian Campbell Jan 2023

“I Certainly Didn’T Expect The Spanish Inquisition!”: Politics Of Transculturation In A Spanish Enclave In North Africa, Brian Campbell, Brian Campbell

School of Law, Humanities and Social Sciences

No abstract provided.


Uptake, Distribution And Elimination Of Palladium-Doped Polystyrene Nanoplastics In Rainbow Trout (Oncorhynchus Mykiss) Following Dietary Exposure, Nathaniel J. Clark, Farhan R. Khan, Charlotte Crowther, Denise M. Mitrano, Richard C. Thompson Jan 2023

Uptake, Distribution And Elimination Of Palladium-Doped Polystyrene Nanoplastics In Rainbow Trout (Oncorhynchus Mykiss) Following Dietary Exposure, Nathaniel J. Clark, Farhan R. Khan, Charlotte Crowther, Denise M. Mitrano, Richard C. Thompson

School of Health Professions

No abstract provided.


An Investigation Of Organic Dining Behaviour In Restaurants At Three Selected Cities In The Uk: A Holistic Approach, Lokman Dinc Jan 2023

An Investigation Of Organic Dining Behaviour In Restaurants At Three Selected Cities In The Uk: A Holistic Approach, Lokman Dinc

Plymouth Business School Theses

An Investigation of Organic Dining Behaviour In Restaurants At three selected cities in the UK : A Holistic Approach Lokman Dinc Abstract The organic food market has experienced significant growth in recent decades all over the world. Within the context of the UK, a remarkable rise can be seen considering the recent popularisation of organic food products. UK diners are becoming increasingly conscious about what they eat, while several reasons such as health and environmental concerns shape diners’ organic food consumption. With these trends in mind, the aim of this research is to develop a holistic understanding of organic dining …


An Exploration Of The Significant Issues At Work For People With A Diagnosed Mental Health Issue, From The Perspective Of Individuals And Line Managers., Lindsay Louise Rose Badger Jan 2023

An Exploration Of The Significant Issues At Work For People With A Diagnosed Mental Health Issue, From The Perspective Of Individuals And Line Managers., Lindsay Louise Rose Badger

Plymouth Business School Theses

This thesis presents findings from an exploratory, in-depth qualitative research project that focused upon surfacing and exploring the significant issues at work for people with diagnosed mental health issues, from the perspective of individuals and line managers. There is growing awareness of the number of people in work with mental health issues; an estimated one in six workers (Elliott et al., 2008; McManus et al., 2016) and the organisational costs: an estimated £42 to £45billion per year (Hampson & Jacob, 2020). The current research field of mental health issues at work focuses upon how work can shape individuals’ mental health …


The Perceived Value Co-Creation And The Degree Of Value Co-Creation Of Chinese Senior Travellers: A Case Study In Guizhou Province (China), Yu Lei Jan 2023

The Perceived Value Co-Creation And The Degree Of Value Co-Creation Of Chinese Senior Travellers: A Case Study In Guizhou Province (China), Yu Lei

Plymouth Business School Theses

Gifted with the reality that the number of aged people has been growing at a high rate of speed from year to year, China has great potential to benefit from the development of senior tourism. Besides, value co-creation has become a more and more attractive research topic in tourism context. However, although previous research (including both English and Chinese literature) has paid considerable attention to value co-creation, few studies have focused on senior travellers’ attitudes on value co-creation in tourism industry. As mentioned above, since more and more Chinese seniors show great interest in tourism-related activities, especially in the post …


Mouthwashes: Alternatives And Future Directions, Brett Duane, Tami Yap, Prasanna Neelakantan, Robert Anthonappa, Raul Bescos, Colman Mcgrath, Michael Mccullough, Zoë Brookes Jan 2023

Mouthwashes: Alternatives And Future Directions, Brett Duane, Tami Yap, Prasanna Neelakantan, Robert Anthonappa, Raul Bescos, Colman Mcgrath, Michael Mccullough, Zoë Brookes

Peninsula Dental School

This narrative review summarises “alternative” or “natural” over-the-counter (OTC) mouthwashes not covered elsewhere in this supplement and newly emerging products, as potential mouthwashes of the future. The “natural” mouthwashes reviewed include saltwater, baking soda, coconut oil, charcoal, propolis, seaweeds, and probiotics. Other than essential oils, it is apparent that their clinical effectiveness is still under debate, but there is some evidence to suggest that propolis reduces plaque and gingivitis. This review also covers the host immune response, via novel anti-inmmunomodulant mouthwashes, such as erythropoietin to reduce inflammation with oral mucositis (OM) after radiotherapy. The emerging concept of nanoparticle-containing mouthwashes, such …