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Articles 1321 - 1350 of 6794
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Protect Earth’S Orbit: Avoid High Seas Mistakes, Imogen E. Napper, Alasdair J. Davies, Moriba Jah, Kimberley R. Miner, Richard C. Thompson, Melissa Quinn, Heather J. Koldewey
Protect Earth’S Orbit: Avoid High Seas Mistakes, Imogen E. Napper, Alasdair J. Davies, Moriba Jah, Kimberley R. Miner, Richard C. Thompson, Melissa Quinn, Heather J. Koldewey
School of Biological and Marine Sciences
The global space industry is growing rapidly—the number of satellites in orbit is expected to increase from 9000 today (1) to over 60,000 by 2030 (2). In addition, it is estimated that more than 100 trillion untracked pieces of old satellites are already in orbit (3). Although the industries and countries using Earth’s orbit are starting to consider sustainability, risks exist in responsibly managing such a vast area with no owner (4). Like the high seas, Earth’s orbit is seen as a global commons, where exploitation of what may appear to be a free resource is growing and the true …
Historical Anthropogenic Disturbances Explain Long-Term Moorland Vegetation Dynamics, Francis Rowney, Ralph M. Fyfe, Leonard Baker, Henry French, Martha B. Koot, Havananda Ombashi, Rhys G. O. Timms
Historical Anthropogenic Disturbances Explain Long-Term Moorland Vegetation Dynamics, Francis Rowney, Ralph M. Fyfe, Leonard Baker, Henry French, Martha B. Koot, Havananda Ombashi, Rhys G. O. Timms
School of Geography, Earth and Environmental Sciences
Upland moorlands are important landscapes, but many are considered degraded as a result of human activities. Consequently, their protection and restoration are of substantial concern. In Europe, restoration activities are often aimed at reversing the effects of 19th and 20th century “agricultural improvements,” which often involved major drainage schemes. However, the ecological effects and long-term ecological context of “agricultural improvement” are not yet fully understood. To develop this understanding, we analyze paleoecological data (pollen, coprophilous fungal spores, microcharcoal) from five upland peatland sites using a range of analytical approaches: cluster analysis, principal component analysis, rate-of-change analysis, and regression analyses incorporating …
Profiling Cognitive–Motor Interference In A Large Sample Of Persons With Progressive Multiple Sclerosis And Impaired Processing Speed: Results From The Cogex Study, R. Veldkamp, M. D’Hooge, B. M. Sandroff, J. Deluca, D. Kos, A. Salter, A. Feinstein, M. P. Amato, G. Brichetto, J. Chataway, R. Farrell, N. D. Chiaravalloti, U. Dalgas, M. Filippi, J. Freeman, R. W. Motl, C. Meza, M. Inglese, M. A. Rocca, G. Cutter, P. Feys
Profiling Cognitive–Motor Interference In A Large Sample Of Persons With Progressive Multiple Sclerosis And Impaired Processing Speed: Results From The Cogex Study, R. Veldkamp, M. D’Hooge, B. M. Sandroff, J. Deluca, D. Kos, A. Salter, A. Feinstein, M. P. Amato, G. Brichetto, J. Chataway, R. Farrell, N. D. Chiaravalloti, U. Dalgas, M. Filippi, J. Freeman, R. W. Motl, C. Meza, M. Inglese, M. A. Rocca, G. Cutter, P. Feys
School of Health Professions
BACKGROUND: Performing cognitive-motor dual tasks (DTs) may result in reduced walking speed and cognitive performance. The effect in persons with progressive multiple sclerosis (pwPMS) having cognitive dysfunction is unknown. OBJECTIVE: To profile DT-performance during walking in cognitively impaired pwPMS and examine DT-performance by disability level. METHODS: Secondary analyses were conducted on baseline data from the CogEx-study. Participants, enrolled with Symbol Digit Modalities Test 1.282 standard deviations below normative value, performed a cognitive single task ([ST], alternating alphabet), motor ST (walking) and DT (both). Outcomes were number of correct answers on the alternating alphabet task, walking speed, and DT-cost (DTC: decline …
Hypervirulent R20291 Clostridioides Difficile Spores Show Disinfection Resilience To Sodium Hypochlorite Despite Structural Changes, Dmitry Malyshev, Imogen Anne Jones, Matthew Mckracken, Rasmus Öberg, Glenn M. Harper, Lovleen Tina Joshi, Magnus Andersson
Hypervirulent R20291 Clostridioides Difficile Spores Show Disinfection Resilience To Sodium Hypochlorite Despite Structural Changes, Dmitry Malyshev, Imogen Anne Jones, Matthew Mckracken, Rasmus Öberg, Glenn M. Harper, Lovleen Tina Joshi, Magnus Andersson
Peninsula Dental School
No abstract provided.
Response Of Dissolved Organic Carbon Dynamics To Salinity In A Constructed Fen Peatland In The Athabasca Oil Sands Region, Emily Prystupa, Scott J. Davidson, Jonathan Price, Maria Strack
Response Of Dissolved Organic Carbon Dynamics To Salinity In A Constructed Fen Peatland In The Athabasca Oil Sands Region, Emily Prystupa, Scott J. Davidson, Jonathan Price, Maria Strack
School of Geography, Earth and Environmental Sciences
In northern Alberta, oil sands mining disturbs the boreal landscape, and reclamation to an ‘equivalent land capability’ is required. Industry is testing peatland construction as part of landscape reclamation. To determine if constructed peatlands can be self-sustaining, an understanding of the cycling of solutes in pore water and their interactions with dissolved organic carbon (DOC) is needed since DOC can represent an important carbon loss from peatlands. DOC is of interest due to its biotic origin and use by the microbial community and impact on carbon budgets. Additionally, salinity as a control on DOC quantity and quality may be important …
A Thermoanalytical Insight Into The Composition Of Biodegradable Polymers And Commercial Products By Ega-Ms And Py-Gc-Ms, Falco F De, Tommaso Nacci, Lee Durndell, Richard C. Thompson, Ilaria Degano, Francesca Modugno
A Thermoanalytical Insight Into The Composition Of Biodegradable Polymers And Commercial Products By Ega-Ms And Py-Gc-Ms, Falco F De, Tommaso Nacci, Lee Durndell, Richard C. Thompson, Ilaria Degano, Francesca Modugno
School of Geography, Earth and Environmental Sciences
Biodegradable polymers are proposed as a potential solution to environmental problems related to plastic pollution. Potential benefits have been suggested in applications such as agricultural mulching and fishing gear, where there can be considerable difficulty recovering products from the environment at the end of their service life. Biodegradation is a complex process influenced by both the properties of the material and the receiving environment in which it needs to biodegrade. Assessing the degradation process necessitates the chemical composition (i.e. polymer and additives) of biodegradable products to be characterised by reliable analytical methods. Pyrolysis coupled to Gas Chromatography and Mass Spectrometry …
Release Of Tephra-Hosted Iron During Early Diagenesis Fingerprinted By Iron Isotopes, Jack Longman, Ann G. Dunlea, Philipp Böning, Martin R. Palmer, Thomas M. Gernon, James Mcmanus, Hayley R. Manners, William B. Homoky, Katharina Pahnke
Release Of Tephra-Hosted Iron During Early Diagenesis Fingerprinted By Iron Isotopes, Jack Longman, Ann G. Dunlea, Philipp Böning, Martin R. Palmer, Thomas M. Gernon, James Mcmanus, Hayley R. Manners, William B. Homoky, Katharina Pahnke
School of Geography, Earth and Environmental Sciences
The micronutrient iron (Fe) plays a fundamental role controlling primary productivity in the upper ocean, with volcanic eruptions and deposition of airborne volcanic material (termed tephra) a potential source of Fe. Here, we investigate the geochemical and Fe isotopic ( Fe) composition of tephra layers, sediments, and mixed tephra-sediment samples from the Integrated Ocean Drilling Program (IODP) Hole 1396C, located offshore the volcanically active island of Montserrat in the Lesser Antilles, Caribbean Sea. We find that buried tephras, which have experienced diagenesis, exhibit lighter Fe (relative to standard IRMM-524a) compositions (down to −0.26 ± 0.04‰, 2SD) than fresh tephra deposited …
Measuring Dna Modifications With The Comet Assay: A Compendium Of Protocols, Awadhesh N. Jha
Measuring Dna Modifications With The Comet Assay: A Compendium Of Protocols, Awadhesh N. Jha
School of Biological and Marine Sciences
The comet assay is a versatile method to detect nuclear DNA damage in individual eukaryotic cells, from yeast to human. The types of damage detected encompass DNA strand breaks and alkali-labile sites (e.g., apurinic/apyrimidinic sites), alkylated and oxidized nucleobases, DNA–DNA crosslinks, UV-induced cyclobutane pyrimidine dimers and some chemically induced DNA adducts. Depending on the specimen type, there are important modifications to the comet assay protocol to avoid the formation of additional DNA damage during the processing of samples and to ensure sufficient sensitivity to detect differences in damage levels between sample groups. Various applications of the comet assay have been …
Spatial Memory Predicts Home Range Size And Predation Risk In Pheasants, Robert J.P. Heathcote, Mark A. Whiteside, Christine E. Beardsworth, Horik Jo Van, Philippa R. Laker, Sivan Toledo, Yotam Orchan, Ran Nathan, Joah R. Madden
Spatial Memory Predicts Home Range Size And Predation Risk In Pheasants, Robert J.P. Heathcote, Mark A. Whiteside, Christine E. Beardsworth, Horik Jo Van, Philippa R. Laker, Sivan Toledo, Yotam Orchan, Ran Nathan, Joah R. Madden
School of Biological and Marine Sciences
No abstract provided.
Epibionts Provide Their Basibionts With Associational Resistance To Predation But At A Cost, S Downes, L Firth, Am Knights
Epibionts Provide Their Basibionts With Associational Resistance To Predation But At A Cost, S Downes, L Firth, Am Knights
School of Biological and Marine Sciences
Epibiosis is increasingly considered a survival strategy in space-limited environments. However, epibionts can create a new interface between its host, environment and potential predators which may alter predator-prey relationships and biological functioning. Ex-situ experiments investigated the potential costs and benefits of epibiont barnacles on mortality and feeding rate of the mussel, Mytilus edulis, and its predator, the whelk Nucella lapillus. Mussels with living epibiont barnacles suffered no mortality from whelk predation, but when barnacles were absent, mortality was ~21% over 48 days. Further comparisons revealed the structural complexity of barnacles provided mussels with protection from whelk predation, while the presence …
Neural Responses To Biological Motion Distinguish Autistic And Schizotypal Traits, Matthew Hudson, Severi Santavirta, Vesa Putkinen, Kerttu Seppälä, Lihua Sun, Tomi Karjalainen, Henry K. Karlsson, Jussi Hirvonen, Lauri Nummenmaa
Neural Responses To Biological Motion Distinguish Autistic And Schizotypal Traits, Matthew Hudson, Severi Santavirta, Vesa Putkinen, Kerttu Seppälä, Lihua Sun, Tomi Karjalainen, Henry K. Karlsson, Jussi Hirvonen, Lauri Nummenmaa
School of Psychology
Difficulties in social interactions characterize both autism and schizophrenia, and are correlated in the neurotypical population. It is unknown whether this represents a shared etiology or superficial phenotypic overlap. Both conditions exhibit atypical neural activity in response to the perception of social stimuli and decreased neural synchronization between individuals. This study investigated if neural activity and neural synchronization associated with biological motion perception are differentially associated with autistic and schizotypal traits in the neurotypical population. Participants viewed naturalistic social interactions whilst hemodynamic brain activity was measured with fMRI, which was modelled against a continuous measure of the extent of biological …
“From This Invisible Archipelago”: The Oceanic Ecopoetics Of Craig Santos Perez, Mandy Bloomfield
“From This Invisible Archipelago”: The Oceanic Ecopoetics Of Craig Santos Perez, Mandy Bloomfield
School of Law, Humanities and Social Sciences
No abstract provided.
Origination Of The Modern-Style Diversity Gradient 15 Million Years Ago, Isabel S. Fenton, Tracy Aze, Alexander Farnsworth, Paul Valdes, Erin E. Saupe
Origination Of The Modern-Style Diversity Gradient 15 Million Years Ago, Isabel S. Fenton, Tracy Aze, Alexander Farnsworth, Paul Valdes, Erin E. Saupe
School of Biological and Marine Sciences
The latitudinal diversity gradient (LDG) is a prevalent feature of modern ecosystems across diverse clades1–4. Recognized for well over a century, the causal mechanisms for LDGs remain disputed, in part because numerous putative drivers simultaneously covary with latitude1,3,5. The past provides the opportunity to disentangle LDG mechanisms because the relationships among biodiversity, latitude and possible causal factors have varied over time6–9. Here we quantify the emergence of the LDG in planktonic foraminifera at high spatiotemporal resolution over the past 40 million years, finding that a modern-style gradient arose only 15 million years ago. Spatial …
Combined Molnupiravir-Nirmatrelvir Treatment Improves The Inhibitory Effect On Sars-Cov-2 In Macaques, Kyle Rosenke, Matt C. Lewis, F Feldmann, Eric Bohrnsen, Benjamin Schwarz, Atsushi Okumura, W. Forrest Bohler, Julie Callison, Carl Shaia, Catharine M. Bosio, Jamie Lovaglio, Greg Saturday, Michael A. Jarvis, H Feldmann
Combined Molnupiravir-Nirmatrelvir Treatment Improves The Inhibitory Effect On Sars-Cov-2 In Macaques, Kyle Rosenke, Matt C. Lewis, F Feldmann, Eric Bohrnsen, Benjamin Schwarz, Atsushi Okumura, W. Forrest Bohler, Julie Callison, Carl Shaia, Catharine M. Bosio, Jamie Lovaglio, Greg Saturday, Michael A. Jarvis, H Feldmann
School of Biomedical Sciences
The periodic emergence of SARS-CoV-2 variants of concern (VOCs) with unpredictable clinical severity and ability to escape preexisting immunity emphasizes the continued need for antiviral interventions. Two small molecule inhibitors, molnupiravir (MK-4482), a nucleoside analog, and nirmatrelvir (PF-07321332), a 3C-like protease inhibitor, have recently been approved as monotherapy for use in high-risk patients with COVID-19. As preclinical data are only available for rodent and ferret models, here we assessed the efficacy of MK-4482 and PF-07321332 alone and in combination against infection with the SARS-CoV-2 Delta VOC in the rhesus macaque COVID-19 model. Macaques were infected with the SARS-CoV-2 Delta variant …
Whole Genomes Of Deep-Sea Sponge-Associated Bacteria Exhibit High Novel Natural Product Potential, Poppy J. Hesketh-Best, Grant G. January, Matthew J. Koch, Philip J. Warburton, Kerry L. Howell, Mathew Upton
Whole Genomes Of Deep-Sea Sponge-Associated Bacteria Exhibit High Novel Natural Product Potential, Poppy J. Hesketh-Best, Grant G. January, Matthew J. Koch, Philip J. Warburton, Kerry L. Howell, Mathew Upton
School of Biomedical Sciences
Abstract Global antimicrobial resistance is a health crisis that can change the face of modern medicine. Exploring diverse natural habitats for bacterially-derived novel antimicrobial compounds has historically been a successful strategy. The deep-sea presents an exciting opportunity for the cultivation of taxonomically novel organisms and exploring potentially chemically novel spaces. In this study, the draft genomes of 12 bacteria previously isolated from the deep-sea sponges Phenomena carpenteri and Hertwigia sp. are investigated for the diversity of specialized secondary metabolites. In addition, early data support the production of antibacterial inhibitory substances produced from a number of these strains, including activity against …
Corrigendum: Strengthened Multi-Stakeholder Linkages In Valuation Studies Is Critical For Improved Decision Making Outcomes For Valuable Mangroves – The Malaysian Case Study, Soon Loong Lee, Amy Yee Hui Then, Hong Ching Goh, Caroline Hattam, Andrew Edwards-Jones, Melanie C. Austen
Corrigendum: Strengthened Multi-Stakeholder Linkages In Valuation Studies Is Critical For Improved Decision Making Outcomes For Valuable Mangroves – The Malaysian Case Study, Soon Loong Lee, Amy Yee Hui Then, Hong Ching Goh, Caroline Hattam, Andrew Edwards-Jones, Melanie C. Austen
School of Biological and Marine Sciences
No abstract provided.
Antiseizure Medications Prescribing For Behavioural And Psychiatric Concerns In Adults With An Intellectual Disability Living In England, David Branford, James J. Sun, Rohit Shankar
Antiseizure Medications Prescribing For Behavioural And Psychiatric Concerns In Adults With An Intellectual Disability Living In England, David Branford, James J. Sun, Rohit Shankar
Peninsula Medical School
Antiseizure medications (ASMs) are the second most widely prescribed psychotropic for people with intellectual disabilities in England. Multiple psychotropic prescribing is prevalent in almost half of people with intellectual disabilities on ASMs. This analysis identifies limited evidence of ASM benefit in challenging behaviour management and suggests improvements needed to inform clinical practice.
Generative Music With Partitioned Quantum Cellular Automata, Eduardo Reck Miranda, Hari Shaji
Generative Music With Partitioned Quantum Cellular Automata, Eduardo Reck Miranda, Hari Shaji
School of Art, Design and Architecture
Cellular automata (CA) are abstract computational models of dynamic systems that change some features with space and time. Music is the art of organising sounds in space and time, and it can be modelled as a dynamic system. Hence, CA are of interest to composers working with generative music. The art of generating music with CA hinges on the design of algorithms to evolve patterns of data and methods to render those patterns into musical forms. This paper introduces methods for creating original music using partitioned quantum cellular automata (PQCA). PQCA consist of an approach to implementing CA on quantum …
Action Slips In Food Choices: A Measure Of Habits And Goal-Directed Control, Katie M.J. Wood, Tina Seabrooke, Chris J. Mitchell
Action Slips In Food Choices: A Measure Of Habits And Goal-Directed Control, Katie M.J. Wood, Tina Seabrooke, Chris J. Mitchell
School of Psychology
No abstract provided.
Impact Of Polyester And Cotton Microfibers On Growth And Sublethal Biomarkers In Juvenile Mussels, C Walkinshaw, Tj Tolhurst, Pk Lindeque, Rc Thompson, M Cole
Impact Of Polyester And Cotton Microfibers On Growth And Sublethal Biomarkers In Juvenile Mussels, C Walkinshaw, Tj Tolhurst, Pk Lindeque, Rc Thompson, M Cole
School of Biological and Marine Sciences
Anthropogenic microfibres are a prevalent, persistent and globally distributed form of marine debris. Evidence of microfibre ingestion has been demonstrated in a range of organisms, including Mytilus spp. (mussels), but the extent of any impacts on these organisms are poorly understood. This study investigates, for the first time, the effect of exposing juvenile mussels to polyester and cotton microfibres at environmentally relevant concentrations (both current and predicted future scenarios) over a chronic timescale (94 days). Sublethal biomarkers included growth rate, respiration rate and clearance rate. Mussels were exposed to polyester (median length 149 µm) and cotton (median length 132 µm) …
Pattern Recognition Reveals Sex‐Dependent Neural Substrates Of Sexual Perception, Vesa Putkinen, S Nazari‐Farsani, Tomi Karjalainen, Severi Santavirta, Matthew Hudson, Kerttu Seppälä, Lihua Sun, Henry K. Karlsson, Jussi Hirvonen, Lauri Nummenmaa
Pattern Recognition Reveals Sex‐Dependent Neural Substrates Of Sexual Perception, Vesa Putkinen, S Nazari‐Farsani, Tomi Karjalainen, Severi Santavirta, Matthew Hudson, Kerttu Seppälä, Lihua Sun, Henry K. Karlsson, Jussi Hirvonen, Lauri Nummenmaa
School of Psychology
Sex differences in brain activity evoked by sexual stimuli remain elusive despite robust evidence for stronger enjoyment of and interest toward sexual stimuli in men than in women. To test whether visual sexual stimuli evoke different brain activity patterns in men and women, we measured hemodynamic brain activity induced by visual sexual stimuli in two experiments with 91 subjects (46 males). In one experiment, the subjects viewed sexual and nonsexual film clips, and dynamic annotations for nudity in the clips were used to predict hemodynamic activity. In the second experiment, the subjects viewed sexual and nonsexual pictures in an event-related …
Deep Seabed Mining Lacks Social Legitimacy, A Jaeckel, H Harden-Davies, Dj Amon, Der Grient J Van, Q Hanich, Leeuwen J Van, Hj Niner, Katherine Seto
Deep Seabed Mining Lacks Social Legitimacy, A Jaeckel, H Harden-Davies, Dj Amon, Der Grient J Van, Q Hanich, Leeuwen J Van, Hj Niner, Katherine Seto
School of Biological and Marine Sciences
IntroductionThe technology to mine the ocean floor for valuable minerals such as copper, nickel, and cobalt is currently being developed. Scientists have warned repeatedly about potentially serious and irreversible environmental impacts from deep seabed mining (DSM), including but not limited to: removal and destruction of sensitive and poorly known seafloor habitats and species; metal-contaminated and fine-particle sediment plumes that can impact benthic and pelagic fauna; changes to water properties; and increases in noise and light1,2. What remains to be substantially debated are the social impacts of DSM.
A 17-Year Time-Series Of Fungal Environmental Dna From A Coastal Marine Ecosystem Reveals Long-Term Seasonal-Scale And Inter-Annual Diversity Patterns, Nathan Chrismas, R Allen, Mj Allen, Kimberley Bird, Michael Cunliffe
A 17-Year Time-Series Of Fungal Environmental Dna From A Coastal Marine Ecosystem Reveals Long-Term Seasonal-Scale And Inter-Annual Diversity Patterns, Nathan Chrismas, R Allen, Mj Allen, Kimberley Bird, Michael Cunliffe
School of Biological and Marine Sciences
Changing patterns in diversity are a feature of many habitats, with seasonality a major driver of ecosystem structure and function. In coastal marine plankton-based ecosystems, seasonality has been established through long-term time-series of bacterioplankton and protists. Alongside these groups, fungi also inhabit coastal marine ecosystems. If and how marine fungi show long-term intra- and inter-annual diversity patterns is unknown, preventing a comprehensive understanding of marine fungal ecology. Here, we use a 17-year environmental DNA time-series from the English Channel to determine long-term marine fungal diversity patterns. We show that fungal community structure progresses at seasonal and monthly scales and is …
A Comparison Of Stochastic And Deterministic Downscaling In Eddy Resolving Ocean Modelling: The Lakshadweep Sea Case Study, Georgy I. Shapiro, Jose M. Gonzalez-Ondina, Mohammed Salim, Jiada Tu
A Comparison Of Stochastic And Deterministic Downscaling In Eddy Resolving Ocean Modelling: The Lakshadweep Sea Case Study, Georgy I. Shapiro, Jose M. Gonzalez-Ondina, Mohammed Salim, Jiada Tu
School of Biological and Marine Sciences
This study compares the skills of two numerical models at the same horizontal resolution but based on different principles in representing meso- and sub-mesoscale ocean features. The first model, titled LD20-NEMO, was based on solving primitive equations of ocean dynamics. The second model, titled LD20-SDD, used a newer stochastic–deterministic downscaling (SDD) method. Both models had 1/20° resolution, the same meteo forcing, and used outputs from a data assimilating global model at 1/12° resolution available from Copernicus Marine Service (CMEMS). The LD20 models did not assimilate observational data but were physically aware of observations via the parent model. The LD20-NEMO only …
Trait Impressions From Voices Are Formed Rapidly Within 400ms Of Exposure, Mila Mileva, Nadine Lavan
Trait Impressions From Voices Are Formed Rapidly Within 400ms Of Exposure, Mila Mileva, Nadine Lavan
School of Psychology
When seeing a face or hearing a voice, perceivers readily form first impressions of a person's characteristics—are they trustworthy, do they seem aggressive? One of the key claims about trait impressions from faces and voices alike is that these impressions are formed rapidly. For faces, studies have systematically mapped this rapid time course of trait impressions, finding that they are well formed and stable after approximately 100 ms of exposure. For voices, however, no systematic investigation of the time course of trait perception exists. In the current study, listeners provided trait judgments (attractiveness, dominance, trustworthiness) based on recordings of 100 …
Estimate Of Uncertain Cohesive Suspended Sediment Deposition Rate From Uncertain Floc Size In Meghna Estuary, Bangladesh, Sifat Sarwar, Alistair G.L. Borthwick
Estimate Of Uncertain Cohesive Suspended Sediment Deposition Rate From Uncertain Floc Size In Meghna Estuary, Bangladesh, Sifat Sarwar, Alistair G.L. Borthwick
School of Engineering, Computing and Mathematics
Suspended sediment in the Meghna estuary, Bangladesh, typically consists of fine to medium silt near the water surface, silty sand at increasing depth, and sandy silt close to the bed. The behavior of fine, cohesive sediment in a complex environment with multiple drivers, such as river and tidal flows, is comparatively little understood because the deposition and erosion processes depend on many chemical, biological, and physical factors. This article examines the propagation of uncertainty from input floc size to output sedimentation rate in the Meghna estuary, Bangladesh, using a fine-sediment hydro-morphodynamic model that utilizes the cohesive sediment transport module in …
Monitoring And Modelling Marine Zooplankton In A Changing Climate, Lavenia Ratnarajah, Rana Abu-Alhaija, Angus Atkinson, Sonia Batten, Nicholas J. Bax, Kim S. Bernard, Gabrielle Canonico, Astrid Cornils, Jason D. Everett, Maria Grigoratou, Nurul Huda Ahmad Ishak, David Johns, Fabien Lombard, Erik Muxagata, Clare Ostle, Sophie Pitois, Anthony J. Richardson, Katrin Schmidt, Lars Stemmann, Kerrie M. Swadling, Guang Yang, Lidia Yebra
Monitoring And Modelling Marine Zooplankton In A Changing Climate, Lavenia Ratnarajah, Rana Abu-Alhaija, Angus Atkinson, Sonia Batten, Nicholas J. Bax, Kim S. Bernard, Gabrielle Canonico, Astrid Cornils, Jason D. Everett, Maria Grigoratou, Nurul Huda Ahmad Ishak, David Johns, Fabien Lombard, Erik Muxagata, Clare Ostle, Sophie Pitois, Anthony J. Richardson, Katrin Schmidt, Lars Stemmann, Kerrie M. Swadling, Guang Yang, Lidia Yebra
School of Geography, Earth and Environmental Sciences
Zooplankton are major consumers of phytoplankton primary production in marine ecosystems. As such, they represent a critical link for energy and matter transfer between phytoplankton and bacterioplankton to higher trophic levels and play an important role in global biogeochemical cycles. In this Review, we discuss key responses of zooplankton to ocean warming, including shifts in phenology, range, and body size, and assess the implications to the biological carbon pump and interactions with higher trophic levels. Our synthesis highlights key knowledge gaps and geographic gaps in monitoring coverage that need to be urgently addressed. We also discuss an integrated sampling approach …
Diagnostic Performance Of Screening Tools For Depressive Symptoms In Vulnerable Older Patients With Cancer Undergoing Comprehensive Geriatric Assessment (Cga): Results From The Screen Pilot Study, Laura Tack, Ann Sophie Maenhoudt, Lore Ketelaars, Zutter J De, Stefanie Pinson, Laura Keunebrock, Lorenz Haaker, Kathleen Deckmyn, Mathilde Gheysen, Cindy Kenis, Hans Wildiers, Laurence Depoorter, Pieter Jan Geerts, Rebecca Chandler, Tom Boterberg, Patricia Schofield, Christopher N. Parris, Philip R. Debruyne
Diagnostic Performance Of Screening Tools For Depressive Symptoms In Vulnerable Older Patients With Cancer Undergoing Comprehensive Geriatric Assessment (Cga): Results From The Screen Pilot Study, Laura Tack, Ann Sophie Maenhoudt, Lore Ketelaars, Zutter J De, Stefanie Pinson, Laura Keunebrock, Lorenz Haaker, Kathleen Deckmyn, Mathilde Gheysen, Cindy Kenis, Hans Wildiers, Laurence Depoorter, Pieter Jan Geerts, Rebecca Chandler, Tom Boterberg, Patricia Schofield, Christopher N. Parris, Philip R. Debruyne
School of Nursing and Midwifery
Depression is a common and disabling disorder in later life, particularly among people with poor physical health. There are many screening tools available that can be used to examine depressive symptoms; however, not all of them may be appropriate or accurate for older adults with cancer. This pilot study was designed to test the diagnostic performance of two screening tools and their short versions in a cohort of vulnerable (G8 score ≤ 14/17) older patients with cancer undergoing comprehensive geriatric assessment (CGA). The prospective analysis covered 50 vulnerable patients with cancer aged ≥70 years. The diagnostic performance of the Geriatric …
Transeuntis Mundi, A Nomadic Artistic Practice, Cândida Luiza Borges Da Silva
Transeuntis Mundi, A Nomadic Artistic Practice, Cândida Luiza Borges Da Silva
School of Law, Humanities and Social Sciences Theses
In this practice-led Ph.D. research, I investigate how an artistic practice can respond to the migration phenomena performed by human beings across the planet over millennia ¬– what I refer to as the millennial global human journey. Based on the idea of mobility, I chose to frame this research in the articulation of concepts deriving from the prefix trans: transculture, transhumance and transmediality. This research contributes to studies in art composition by developing the processes and concept of transmedial composition, mainly contributing to the field of New Media Art. This investigation resulted in the work Transeuntis Mundi (TM) Project – …
Overexpression Of Both Human Sodium Iodide Symporter (Nis) And Brg1-Bromodomain Synergistically Enhances Radioiodine Sensitivity By Stabilizing P53 Through Npm1 Expression, J Na, C-H Lee, J-K Chung, H Youn
Overexpression Of Both Human Sodium Iodide Symporter (Nis) And Brg1-Bromodomain Synergistically Enhances Radioiodine Sensitivity By Stabilizing P53 Through Npm1 Expression, J Na, C-H Lee, J-K Chung, H Youn
Peninsula Medical School
Improved therapeutic strategies are required to minimize side effects associated with radioiodine gene therapy to avoid unnecessary damage to normal cells and radiation-induced secondary malignancies. We previously reported that codon-optimized sodium iodide symporter (oNIS) enhances absorption of I-131 and that the brahma-associated gene 1 bromodomain (BRG1-BRD) causes inefficient DNA damage repair after high-energy X-ray therapy. To increase the therapeutic effect without applying excessive radiation, we considered the combination of oNIS and BRG1-BRD as gene therapy for the most effective radioiodine treatment. The antitumor effect of I-131 with oNIS or oNIS+BRD expression was examined by tumor xenograft models along with functional …