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Articles 1171 - 1200 of 6794
Full-Text Articles in Entire DC Network
Eyelash Length Attractiveness Across Ethnicities, Farid Pazhoohi, Alan Kingstone
Eyelash Length Attractiveness Across Ethnicities, Farid Pazhoohi, Alan Kingstone
School of Psychology
Eyelashes evolved to protect eyes. An optimum eyelash length functions to protect eyes from external hazards such as contaminations, excessive evaporation or shear stress from airflow. They can also be an indicator of a person's health as various congenital and noncongenital diseases can lead to short or long eyelashes. The current study aimed to extend a recent investigation on the preference for eyelash length in humans from an evolutionary adaptive perspective. Specifically, the current study tested whether the inverted-U function for eyelash length preference recently reported for White faces, generalises to other ethnicities, and whether ethnic background modulates preference for …
Thin And Transient Meltwater Layers And False Bottoms In The Arctic Sea Ice Pack-Recent Insights On These Historically Overlooked Features, Madison M. Smith, Hélène Angot, Emelia J. Chamberlain, Elise S. Droste, Salar Karam, Morven Muilwijk, Alison L. Webb, Stephen D. Archer, Ivo Beck, Byron W. Blomquist, Jeff Bowman, Matthew Boyer, Deborah Bozzato, Melissa Chierici, Jessie Creamean, Alessandra D’Angelo, Bruno Delille, Ilker Fer, Allison A. Fong, Agneta Fransson, Niels Fuchs, Jessie Gardner, Mats A. Granskog, Clara J.M. Hoppe, Mario Hoppema, Mario Hoppmann, Thomas Mock, Sofia Muller, Oliver Müller, Marcel Nicolaus
Thin And Transient Meltwater Layers And False Bottoms In The Arctic Sea Ice Pack-Recent Insights On These Historically Overlooked Features, Madison M. Smith, Hélène Angot, Emelia J. Chamberlain, Elise S. Droste, Salar Karam, Morven Muilwijk, Alison L. Webb, Stephen D. Archer, Ivo Beck, Byron W. Blomquist, Jeff Bowman, Matthew Boyer, Deborah Bozzato, Melissa Chierici, Jessie Creamean, Alessandra D’Angelo, Bruno Delille, Ilker Fer, Allison A. Fong, Agneta Fransson, Niels Fuchs, Jessie Gardner, Mats A. Granskog, Clara J.M. Hoppe, Mario Hoppema, Mario Hoppmann, Thomas Mock, Sofia Muller, Oliver Müller, Marcel Nicolaus
School of Geography, Earth and Environmental Sciences
The rapid melt of snow and sea ice during the Arctic summer provides a significant source of low-salinity meltwater to the surface ocean on the local scale. The accumulation of this meltwater on, under, and around sea ice floes can result in relatively thin meltwater layers in the upper ocean. Due to the small-scale nature of these upper-ocean features, typically on the order of 1 m thick or less, they are rarely detected by standard methods, but are nevertheless pervasive and critically important in Arctic summer. Observations during the Multidisciplinary drifting Observatory for the Study of Arctic Climate (MOSAiC) expedition …
Identity Development, Attraction, And Behaviour Of Heterosexually-Identified Men Who Have Sex With Men: A Scoping Review, E Andrew, S Travis, K Taylor, P Nelson, K Sandra, M Mel, D Frank, M Lauren, B Oliver, B Erin, B Adam, V Daniel, B Cara, S Paul, O Beer
Identity Development, Attraction, And Behaviour Of Heterosexually-Identified Men Who Have Sex With Men: A Scoping Review, E Andrew, S Travis, K Taylor, P Nelson, K Sandra, M Mel, D Frank, M Lauren, B Oliver, B Erin, B Adam, V Daniel, B Cara, S Paul, O Beer
School of Health Professions
No abstract provided.
Restoration Management Of Phosphorus Pollution On Lowland Fen Peatlands: A Data Evidence Review From The Somerset Levels And Moors, Sean Comber, Paul Lunt, Mark Taylor, Natasha Underwood, Ry Crocker, Rob Schindler
Restoration Management Of Phosphorus Pollution On Lowland Fen Peatlands: A Data Evidence Review From The Somerset Levels And Moors, Sean Comber, Paul Lunt, Mark Taylor, Natasha Underwood, Ry Crocker, Rob Schindler
School of Geography, Earth and Environmental Sciences
Eutrophication of wetlands caused by urban, industrial and agricultural run-off is an important environmental problem. Eutrophication is characterized by excessive plant and algal growth due to the increased availability of one or more growth “limiting nutrients”, in freshwater generally considered to be controlled by the bioavailability of phosphorus (P). The Somerset Levels and Moors (SLMs) catchments are subject to intensive agriculture and wastewater inputs which leads to nutrient contamination of the inflow waters, to the extent that they fail Water Framework Directive Good Status targets for P concentrations. In 2021, Natural England downgraded the status of the SLMs Sites of …
Coastal Wave Overtopping: New Nowcast And Monitoring Technologies, Jennifer Brown, Margaret Yelland, Gerd Masselink, Tim Poate, Kit Stokes, Robin Pascal, David Jones, Christopher Cardwell, John Walk, Barry Martin, Peter Ganderton, Louise Darroch, Tom Gardner, Tom Gardner
Coastal Wave Overtopping: New Nowcast And Monitoring Technologies, Jennifer Brown, Margaret Yelland, Gerd Masselink, Tim Poate, Kit Stokes, Robin Pascal, David Jones, Christopher Cardwell, John Walk, Barry Martin, Peter Ganderton, Louise Darroch, Tom Gardner, Tom Gardner
School of Biological and Marine Sciences
It is projected that global mean sea level could rise up to 1 m this century with a strong regional pattern. It is estimated that 20% of England's coastal defenses could fail under just half this rise. Ambitious climate mitigation and adaptation plans may protect 400,000 - 500,000 people, but flood and coastal erosion risks cannot be fully eliminated. Building coastal climate resilience requires accurate wave overtopping prediction tools and nowcast information to prepare for and respond to coastal hazards. In Dawlish, SW England, a new monitoring system to measure concurrent beach level and wave overtopping conditions over a 1-year …
Isolation Of Tumour-Reactive Lymphocytes From Peripheral Blood Via Microfluidic Immunomagnetic Cell Sorting, Zongjie Wang, Sharif Ahmed, Mahmoud Labib, Hansen Wang, Licun Wu, Fatemeh Bavaghar-Zaeimi, Nastaran Shokri, Soraly Blanco, Saraf Karim, Kasia Czarnecka-Kujawa, Edward H. Sargent, A. J.Robert Mcgray, Marc De Perrot, Shana O. Kelley
Isolation Of Tumour-Reactive Lymphocytes From Peripheral Blood Via Microfluidic Immunomagnetic Cell Sorting, Zongjie Wang, Sharif Ahmed, Mahmoud Labib, Hansen Wang, Licun Wu, Fatemeh Bavaghar-Zaeimi, Nastaran Shokri, Soraly Blanco, Saraf Karim, Kasia Czarnecka-Kujawa, Edward H. Sargent, A. J.Robert Mcgray, Marc De Perrot, Shana O. Kelley
Peninsula Medical School
The clinical use of tumour-infiltrating lymphocytes for the treatment of solid tumours is hindered by the need to obtain large and fresh tumour fractions, which is often not feasible in patients with unresectable tumours or recurrent metastases. Here we show that circulating tumour-reactive lymphocytes (cTRLs) can be isolated from peripheral blood at high yield and purity via microfluidic immunomagnetic cell sorting, allowing for comprehensive downstream analyses of these rare cells. We observed that CD103 is strongly expressed by the isolated cTRLs, and that in mice with subcutaneous tumours, tumour-infiltrating lymphocytes isolated from the tumours and rapidly expanded CD8+CD103+ cTRLs isolated …
Repeatability Of Morphological Change On A Sandy Beach Across Multiple Timescales, Chris Blenkinsopp, Paul Bayle, Tom Baldock, Daniel Conley, Gerd Masselink
Repeatability Of Morphological Change On A Sandy Beach Across Multiple Timescales, Chris Blenkinsopp, Paul Bayle, Tom Baldock, Daniel Conley, Gerd Masselink
School of Biological and Marine Sciences
No abstract provided.
Practical Diagnosis Of Cirrhosis In Non-Alcoholic Fatty Liver Disease Using Currently Available Non-Invasive Fibrosis Tests, J Boursier, Marine Roux, Charlotte Costentin, Julien Chaigneau, Céline Fournier-Poizat, Aldo Trylesinski, Cm Canivet, Sophie Michalak, Bail B Le, Valérie Paradis, Pierre Bedossa, Nathalie Sturm, Ledinghen V De, Justine Barthelon, J Boursier, Paul Cales, C Canivet, Thomas Decaens, Adèle Delamarre, Paul Hermabessiere, Marie Irles-Depé, Ledinghen V De, Marie Noelle Hilleret, Isabelle Fouchard-Hubert, Adrien Lannes, Bail B Le, Valérie Moal, Fréderic Oberti, Michael Allison, Peter J. Eddowes, Jeremy F. Cobbold, Jonathan J. Deeks, Peter J. Eddowes, Indra N. Guha, David Sheridan, Emmanuel Tsochatzis, Philip N. Newsome
Practical Diagnosis Of Cirrhosis In Non-Alcoholic Fatty Liver Disease Using Currently Available Non-Invasive Fibrosis Tests, J Boursier, Marine Roux, Charlotte Costentin, Julien Chaigneau, Céline Fournier-Poizat, Aldo Trylesinski, Cm Canivet, Sophie Michalak, Bail B Le, Valérie Paradis, Pierre Bedossa, Nathalie Sturm, Ledinghen V De, Justine Barthelon, J Boursier, Paul Cales, C Canivet, Thomas Decaens, Adèle Delamarre, Paul Hermabessiere, Marie Irles-Depé, Ledinghen V De, Marie Noelle Hilleret, Isabelle Fouchard-Hubert, Adrien Lannes, Bail B Le, Valérie Moal, Fréderic Oberti, Michael Allison, Peter J. Eddowes, Jeremy F. Cobbold, Jonathan J. Deeks, Peter J. Eddowes, Indra N. Guha, David Sheridan, Emmanuel Tsochatzis, Philip N. Newsome
Peninsula Medical School
Unlike for advanced liver fibrosis, the practical rules for the early non-invasive diagnosis of cirrhosis in NAFLD remain not well defined. Here, we report the derivation and validation of a stepwise diagnostic algorithm in 1568 patients with NAFLD and liver biopsy coming from four independent cohorts. The study algorithm, using first the elastography-based tests Agile3+ and Agile4 and then the specialized blood tests FibroMeterV3G and CirrhoMeterV3G, provides stratification in four groups, the last of which is enriched in cirrhosis (71% prevalence in the validation set). A risk prediction chart is also derived to allow estimation of the individual probability of …
Antibiotic Resistance Mediated By Escherichia Coli In Kuwait Marine Environment As Revealed Through Genomic Analysis, Ha Al-Sarawi, Nazima Habibi, Saif Uddin, Awadhesh N. Jha, Ma Al-Sarawi, Brett P. Lyons
Antibiotic Resistance Mediated By Escherichia Coli In Kuwait Marine Environment As Revealed Through Genomic Analysis, Ha Al-Sarawi, Nazima Habibi, Saif Uddin, Awadhesh N. Jha, Ma Al-Sarawi, Brett P. Lyons
School of Biological and Marine Sciences
Antibiotic-resistance gene elements (ARGEs) such as antibiotic-resistance genes (ARGs), integrons, and plasmids are key to the spread of antimicrobial resistance (AMR) in marine environments. Kuwait’s marine area is vulnerable to sewage contaminants introduced by numerous storm outlets and indiscriminate waste disposal near recreational beaches. Therefore, it has become a significant public health issue and warrants immediate investigation. Coliforms, especially Gram-negative Escherichia coli, have been regarded as significant indicators of recent fecal pollution and carriers of ARGEs. In this study, we applied a genome-based approach to identify ARGs’ prevalence in E. coli isolated from mollusks and coastal water samples collected in …
Toward Understanding The Environmental Risks Of Combined Microplastics/Nanomaterials Exposures: Unveiling Zno Transformations After Adsorption Onto Polystyrene Microplastics In Environmental Solutions, Ma Gomez‐Gonzalez, Silva‐Ferreira T Da, Nathaniel Clark, Robert Clough, Paul D. Quinn, Julia E. Parker
Toward Understanding The Environmental Risks Of Combined Microplastics/Nanomaterials Exposures: Unveiling Zno Transformations After Adsorption Onto Polystyrene Microplastics In Environmental Solutions, Ma Gomez‐Gonzalez, Silva‐Ferreira T Da, Nathaniel Clark, Robert Clough, Paul D. Quinn, Julia E. Parker
School of Health Professions
AbstractOver recent decades, there has been a dramatic increase in the manufacture of engineered nanomaterials, which has inevitably led to their environmental release. Zinc oxide (ZnO) is among the more abundant nanomaterial manufactured due to its advantageous properties, used for piezoelectric, semiconducting, and antibacterial purposes. Plastic waste is ubiquitous and may break down or delaminate into smaller microplastics, leaving open the question of whether these small polymers may alter the fate of ZnO through adsorption within aquatic media (tap‐water and seawater). Here, scanning electron microscopy analysis confirms the effective Zn nano/microstructures adsorption onto polystyrene surfaces after only 24‐h incubation in …
Sediment Sorting Within A Relatively Wave-Exposed And Sandy Subtidal Seagrass (Zostera Marina) Meadow, Gerd Masselink
Sediment Sorting Within A Relatively Wave-Exposed And Sandy Subtidal Seagrass (Zostera Marina) Meadow, Gerd Masselink
Faculty of Science and Engineering Datasets
The sediment data set consists of a single spreadsheet with self-explanatory sheets. Sediments were collected from 64 sample locations. The samples were analysed in the laboratory by MSc student Tom Brown and his PhD thesis is included as it contains an extensive description of the analysis methods. Dataset Description: This is the full sediment data set collected in august 2020 from the Great Ganinick seagrass meadow in the isles of Scilly
Northerly Range Expansion And First Confirmed Records Of The Smalltooth Sand Tiger Shark, Odontaspis Ferox, In The United Kingdom And Ireland, David J. Curnick, Phil Hosegood
Northerly Range Expansion And First Confirmed Records Of The Smalltooth Sand Tiger Shark, Odontaspis Ferox, In The United Kingdom And Ireland, David J. Curnick, Phil Hosegood
School of Biological and Marine Sciences
Three Odontaspis ferox (confirmed by mtDNA barcoding) were found in the English Channel and Celtic Sea in 2023 at Lepe, UK (50.7846, −1.3508), Kilmore Quay, Ireland (52.1714, −6.5937), and Lyme Bay, UK (50.6448, −2.9302). These are the first records of O. ferox in either country, and extend the species' range by over three degrees of latitude, to >52° N. They were ~275 (female), 433 (female), and 293 cm (male) total length, respectively. These continue a series of new records, possibly indicative of a climate change−induced shift in the species' range.
In Silico Prediction Of Acute Chemical Toxicity Of Biocides In Marine Crustaceans Using Machine Learning, Rama Krishnan, Ian S. Howard, Sean Comber, Awadhesh N. Jha
In Silico Prediction Of Acute Chemical Toxicity Of Biocides In Marine Crustaceans Using Machine Learning, Rama Krishnan, Ian S. Howard, Sean Comber, Awadhesh N. Jha
School of Engineering, Computing and Mathematics
Biocides are a heterogeneous group of chemical substances intended to control the growth or kill undesired organisms. Due to their extensive use, they enter marine ecosystems via non-point sources and may pose a threat to ecologically important non-target organisms. Consequently, industries and regulatory agencies have recognized the ecotoxicological hazard potential of biocides. However, the prediction of biocide chemical toxicity on marine crustaceans has not been previously evaluated. This study aims to provide in silico models capable of classifying structurally diverse biocidal chemicals into different toxicity categories and predict acute chemical toxicity (LC50) in marine crustaceans using a set of calculated …
Early-Phase Neuroplasticity Induced By Offline Transcranial Ultrasound Stimulation In Primates, N Bault, Sn Yaakub, E Fouragnan
Early-Phase Neuroplasticity Induced By Offline Transcranial Ultrasound Stimulation In Primates, N Bault, Sn Yaakub, E Fouragnan
School of Psychology
No abstract provided.
Latitudinal Variation In The Potential Activity Of Atlantic Ocean Bacterioplankton Revealed Through 16s Rrna And 16s Rrna Gene Metabarcoding, Ro Allen, Kimberley E. Bird, J. Colin Murrell, Michael Cunliffe
Latitudinal Variation In The Potential Activity Of Atlantic Ocean Bacterioplankton Revealed Through 16s Rrna And 16s Rrna Gene Metabarcoding, Ro Allen, Kimberley E. Bird, J. Colin Murrell, Michael Cunliffe
School of Biological and Marine Sciences
The activities of bacterioplankton sustain open ocean biogeochemical and ecological processes, however, little is known about the activity of specific bacterioplankton, especially related to their biogeography across oceanic scales. The Atlantic is the second largest of the world’s oceans and has an essential role in the global carbon cycle. Here, we show congruence in the structure of 16S rRNA and 16S rRNA gene derived bacterioplankton communities throughout the Atlantic Ocean from temperate to tropical regions. We used 16S rRNA:16S rRNA gene ratios as a phylogenetically resolved proxy for potential activity, demonstrating ocean-scale patterns of putative oligotrophy and copiotrophy in major …
Phenomics As An Approach To Comparative Developmental Physiology, Jamie C.S. Mccoy, John I. Spicer, Ziad Ibbini, Oliver Tills
Phenomics As An Approach To Comparative Developmental Physiology, Jamie C.S. Mccoy, John I. Spicer, Ziad Ibbini, Oliver Tills
School of Biological and Marine Sciences
The dynamic nature of developing organisms and how they function presents both opportunity and challenge to researchers, with significant advances in understanding possible by adopting innovative approaches to their empirical study. The information content of the phenotype during organismal development is arguably greater than at any other life stage, incorporating change at a broad range of temporal, spatial and functional scales and is of broad relevance to a plethora of research questions. Yet, effectively measuring organismal development, and the ontogeny of physiological regulations and functions, and their responses to the environment, remains a significant challenge. “Phenomics”, a global approach to …
Toll-Like Receptor 4 And Macrophage Scavenger Receptor 1 Crosstalk Regulates Phagocytosis Of A Fungal Pathogen, Chinaemerem U. Onyishi, Guillaume E. Desanti, Alex L. Wilkinson, Samuel Lara-Reyna, Eva Maria Frickel, Gyorgy Fejer, Olivier D. Christophe, Clare E. Bryant, Subhankar Mukhopadhyay, Siamon Gordon, Robin C. May
Toll-Like Receptor 4 And Macrophage Scavenger Receptor 1 Crosstalk Regulates Phagocytosis Of A Fungal Pathogen, Chinaemerem U. Onyishi, Guillaume E. Desanti, Alex L. Wilkinson, Samuel Lara-Reyna, Eva Maria Frickel, Gyorgy Fejer, Olivier D. Christophe, Clare E. Bryant, Subhankar Mukhopadhyay, Siamon Gordon, Robin C. May
School of Biomedical Sciences
The opportunistic fungal pathogen Cryptococcus neoformans causes lethal infections in immunocompromised patients. Macrophages are central to the host response to cryptococci; however, it is unclear how C. neoformans is recognised and phagocytosed by macrophages. Here we investigate the role of TLR4 in the non-opsonic phagocytosis of C. neoformans. We find that loss of TLR4 function unexpectedly increases phagocytosis of non-opsonised cryptococci by murine and human macrophages. The increased phagocytosis observed in Tlr4−/− cells was dampened by pre-treatment of macrophages with oxidised-LDL, a known ligand of scavenger receptors. The scavenger receptor, macrophage scavenger receptor 1 (MSR1) (also known as SR-A1 or …
Ocean-Based Climate Action And Human Rights Implications Under The International Climate Change Regime, Elisa Morgera, Mitchell Lennan, Kati Kulovesi, Bianca G La, Holly J. Niner, Ellycia Harrould-Kolieb, Piva E Recio, Jeremy Hills, Mara Ntona, Alana Malinde Sn Lancaster, Mia Strand, Bernadette Snow, Kira Erwin, Lynne Shannon, Sian Rees, Kieran Hyder, Georg Engelhard, Kerry Howell
Ocean-Based Climate Action And Human Rights Implications Under The International Climate Change Regime, Elisa Morgera, Mitchell Lennan, Kati Kulovesi, Bianca G La, Holly J. Niner, Ellycia Harrould-Kolieb, Piva E Recio, Jeremy Hills, Mara Ntona, Alana Malinde Sn Lancaster, Mia Strand, Bernadette Snow, Kira Erwin, Lynne Shannon, Sian Rees, Kieran Hyder, Georg Engelhard, Kerry Howell
School of Biological and Marine Sciences
After drawing attention to the crucial role of marine biodiversity, including that of deep-sea ecosystems, in current scientific understanding of the ocean-climate nexus, this article highlights the limited extent to which the international climate change regime has so far addressed the ocean. The focus then shifts to how the international climate change regime could contribute to the protection of marine biodiversity as part of mitigation, adaptation and finance, taking into account human rights impacts and standards, drawing a comparison with REDD+. The article concludes with an original proposal, inspired by the Climate and Clean Air Coalition, to develop urgent, synergistic …
A Storm Driven Turbidity Maximum In A Microtidal Estuary, M Postacchini, Aj Manning, J Calantoni, Jp Smith, M Brocchini
A Storm Driven Turbidity Maximum In A Microtidal Estuary, M Postacchini, Aj Manning, J Calantoni, Jp Smith, M Brocchini
School of Biological and Marine Sciences
Many macro- and mesotidal estuaries are characterized by Turbidity Maxima Zones (TMZs), regions with suspended solid concentrations that are much higher than those found throughout the rest of the estuary. Such regions are located near the upriver limit of salt intrusion and their position and extent are modulated and driven by tidal oscillations, especially in estuaries where tidal forcing is large. Hence, pronounced TMZs are not typically expected in micro-tidal estuaries. Field experiments were carried out in the microtidal estuary of the Misa River (northeast coast of Italy) with the aim to analyze riverine-coastal ocean interactions during different climatic conditions, …
Reconstructing Ancient Dispersal Through Antarctica: A Case Study Of Stream-Inhabiting Beetles, V Sykora, Leonel Herrera-Alsina, Crystal Maier, Nicolás Rafael Martínez-Román, Miguel Archangelsky, David T. Bilton, Matthias Seidel, Richard A.B. Leschen, Martin Fikáček
Reconstructing Ancient Dispersal Through Antarctica: A Case Study Of Stream-Inhabiting Beetles, V Sykora, Leonel Herrera-Alsina, Crystal Maier, Nicolás Rafael Martínez-Román, Miguel Archangelsky, David T. Bilton, Matthias Seidel, Richard A.B. Leschen, Martin Fikáček
School of Biological and Marine Sciences
Aim Although Antarctica hosted a diverse fauna and flora in the past, its modern climate is too extreme for many lineages: their recent extinction makes it difficult to include the continent in historical biogeographical analyses. We use southern temperate stream‐inhabiting beetles as a model to explore whether Antarctica may be included in historical biogeographic reconstructions in a group absent from Antarctica today, and to test its role in shaping the current distribution of stream‐inhabiting insects. Taxon Coleoptera, Elmidae. Location Southern Hemisphere temperate regions and Antarctica. Methods We included Antarctica in historical biogeographic analyses indirectly, as a component of distance matrices …
An Attenuated Herpesvirus Vectored Vaccine Candidate Induces T-Cell Responses Against Highly Conserved Porcine Reproductive And Respiratory Syndrome Virus M And Nsp5 Proteins That Are Unable To Control Infection, Brito Rcf De, Kerry Holtham, Jessica Roser, Jack E. Saunders, Yvonne Wezel, Summer Henderson, Thekla Mauch, Beatriz Sanz-Bernardo, Jean Pierre Frossard, Matthieu Bernard, Fabian Z.X. Lean, Alejandro Nunez, Simon Gubbins, Nicolás M. Suárez, Andrew J. Davison, Michael J. Francis, Michael Huether, Hafid Benchaoui, Jeremy Salt, Veronica L. Fowler, Michael A. Jarvis, Simon P. Graham
An Attenuated Herpesvirus Vectored Vaccine Candidate Induces T-Cell Responses Against Highly Conserved Porcine Reproductive And Respiratory Syndrome Virus M And Nsp5 Proteins That Are Unable To Control Infection, Brito Rcf De, Kerry Holtham, Jessica Roser, Jack E. Saunders, Yvonne Wezel, Summer Henderson, Thekla Mauch, Beatriz Sanz-Bernardo, Jean Pierre Frossard, Matthieu Bernard, Fabian Z.X. Lean, Alejandro Nunez, Simon Gubbins, Nicolás M. Suárez, Andrew J. Davison, Michael J. Francis, Michael Huether, Hafid Benchaoui, Jeremy Salt, Veronica L. Fowler, Michael A. Jarvis, Simon P. Graham
School of Biomedical Sciences
Porcine reproductive and respiratory syndrome virus (PRRSV) remains a leading cause of economic loss in pig farming worldwide. Existing commercial vaccines, all based on modified live or inactivated PRRSV, fail to provide effective immunity against the highly diverse circulating strains of both PRRSV-1 and PRRSV-2. Therefore, there is an urgent need to develop more effective and broadly active PRRSV vaccines. In the absence of neutralizing antibodies, T cells are thought to play a central role in controlling PRRSV infection. Herpesvirus-based vectors are novel vaccine platforms capable of inducing high levels of T cells against encoded heterologous antigens. Therefore, the aim …
Alcohol Consumption And Measures Of Sarcopenic Muscle Risk: Cross-Sectional And Prospective Associations Within The Uk Biobank Study, Jane Skinner, Lee Shepstone, Mary Hickson, Ailsa A. Welch
Alcohol Consumption And Measures Of Sarcopenic Muscle Risk: Cross-Sectional And Prospective Associations Within The Uk Biobank Study, Jane Skinner, Lee Shepstone, Mary Hickson, Ailsa A. Welch
School of Health Professions
Alcohol intake is a major modifiable risk factor for many diseases. Alcohol can also damage skeletal muscle health during ageing which in turn increases risk of sarcopenia, frailty and falls but this relationship is understudied. The aim of this study was to model the relationship between a full range of alcohol consumption and components of sarcopenic risk, skeletal muscle mass and function, in middle-aged and younger older-aged men and women. A cross-sectional analyses was undertaken of 196,561 white participants from the UK Biobank with longitudinal analysis also in 12,298 of these participants, with outcome measures for the latter repeated after …
Challenges And Opportunities In Achieving Sustainable Mud Crab Aquaculture In Tropical Coastal Regions, Elina Apine, Prashanth Ramappa, Ramachandra Bhatta, Lucy M. Turner, Lynda D. Rodwell
Challenges And Opportunities In Achieving Sustainable Mud Crab Aquaculture In Tropical Coastal Regions, Elina Apine, Prashanth Ramappa, Ramachandra Bhatta, Lucy M. Turner, Lynda D. Rodwell
School of Biological and Marine Sciences
Aquaculture plays a significant role in food security and provides livelihoods and employment for millions of people among coastal communities worldwide. However, the growing aquaculture sector has also created debates around its long-term ecological sustainability, economic viability, potential social inequalities and governance issues. We investigated the perceived challenges and opportunities to achieving sustainable mud crab aquaculture in tropical coastal regions by using the case study of coastal mud crab farms in Andhra Pradesh, India. Informed by perceptions and indicative financial data from a sample of stakeholders we investigated the potential economic outcomes under different scenarios representing varying yield levels, risk …
Satellite-Based Shoreline Detection Along High-Energy Macrotidal Coasts And Influence Of Beach State, Aikaterini Konstantinou, Tim Scott, Gerd Masselink, Kit Stokes, Daniel Conley, Bruno Castelle
Satellite-Based Shoreline Detection Along High-Energy Macrotidal Coasts And Influence Of Beach State, Aikaterini Konstantinou, Tim Scott, Gerd Masselink, Kit Stokes, Daniel Conley, Bruno Castelle
School of Biological and Marine Sciences
Earth observation coupled with novel image analysis techniques now present a unique and powerful tool for the historical study of shoreline change at local to global scale. However, satellite-derived shoreline (SDS) data is limited in certain areas and is associated with large uncertainties relating to environmental factors, tidal range, and wave action. We use 14 years of monthly topographic surveys at two macrotidal sites in the UK representing end members of beach type (reflective, dissipative) to investigate the influence of tidal elevation and wave action on SDS accuracy. We find that applying appropriate water level corrections can significantly improve SDS …
An Extended Mtdna Phylogeography For The Alpine Newt Illuminates The Provenance Of Introduced Populations, J Robbemont, Veldhuijzen S Van, J.R. A Steven, J Ambu, R Boyle, D Canestrelli, M Cvijanović, C Dufresnes, C Ennis, R Gandola, D Jablonski, A Julian, D Kranželić, S Lukanov, I Martínez-Solano, R Montgomery, B Naumov, M O’Neill, N Alexandra, M Pabijan, R Puschendorf, D Salvi, B Schmidt, K Sotiropoulos, F Stanescu, D Stanković, S Stapelton, E Šunje, M Szabolcs, E Vacheva, D Willis, A Zimić, J France, Wrm Meilink, T Stark, Rpjh Struij, A Theodoropoulos, Visser1 Mc De, B Wielstra
An Extended Mtdna Phylogeography For The Alpine Newt Illuminates The Provenance Of Introduced Populations, J Robbemont, Veldhuijzen S Van, J.R. A Steven, J Ambu, R Boyle, D Canestrelli, M Cvijanović, C Dufresnes, C Ennis, R Gandola, D Jablonski, A Julian, D Kranželić, S Lukanov, I Martínez-Solano, R Montgomery, B Naumov, M O’Neill, N Alexandra, M Pabijan, R Puschendorf, D Salvi, B Schmidt, K Sotiropoulos, F Stanescu, D Stanković, S Stapelton, E Šunje, M Szabolcs, E Vacheva, D Willis, A Zimić, J France, Wrm Meilink, T Stark, Rpjh Struij, A Theodoropoulos, Visser1 Mc De, B Wielstra
School of Biological and Marine Sciences
Many herpetofauna species have been introduced outside of their native range. MtDNA barcoding is regularly used to determine the provenance of such populations. The alpine newt has been introduced across the Netherlands, the United Kingdom and Ireland. However, geographical mtDNA structure across the natural range of the alpine newt is still incompletely understood and certain regions are severely undersampled. We collect mtDNA sequence data of over seven hundred individuals, from both the native and the introduced range. The main new insights from our extended mtDNA phylogeography are that 1) haplotypes from Spain do not form a reciprocally monophyletic clade, but …
Graduates’ Preparedness For The Changing Doctor‐Patient Relationship: A Qualitative Study, Nicola Brennan, Nicola Langdon, Natasha Keates, Karen Mattick, Thomas Gale
Graduates’ Preparedness For The Changing Doctor‐Patient Relationship: A Qualitative Study, Nicola Brennan, Nicola Langdon, Natasha Keates, Karen Mattick, Thomas Gale
Peninsula Medical School
BACKGROUND: A positive doctor-patient relationship is a crucial part of high-quality patient care. There is a general perception that it has been changing in recent years however there is a lack of evidence for this. Adapting to the changing doctor-patient relationship has been identified as an important skill doctors of the future must possess. This study explores 1). multiple stakeholder perspectives on how the doctor-patient relationship is changing and 2). in what ways medical graduates are prepared for working in this changing doctor-patient relationship. METHODS: We conducted a national qualitative study involving semi-structured interviews with multiple stakeholders across the UK. …
The Care Of Transgender Patients In Critical Care: A Call To Action, L Flower, A Humphreys, S Edwardson
The Care Of Transgender Patients In Critical Care: A Call To Action, L Flower, A Humphreys, S Edwardson
Peninsula Medical School
No abstract provided.
Predicting Narcissistic Personality Traits From Brain And Psychological Features: A Supervised Machine Learning Approach, Khanitin Jornkokgoud, Teresa Baggio, Md Faysal, Richard Bakiaj, Peera Wongupparaj, Remo Job, Alessandro Grecucci
Predicting Narcissistic Personality Traits From Brain And Psychological Features: A Supervised Machine Learning Approach, Khanitin Jornkokgoud, Teresa Baggio, Md Faysal, Richard Bakiaj, Peera Wongupparaj, Remo Job, Alessandro Grecucci
School of Psychology
Narcissism is a multifaceted construct often linked to pathological conditions whose neural correlates are still poorly understood. Previous studies have reported inconsistent findings related to the neural underpinnings of narcissism, probably due to methodological limitations such as the low number of participants or the use of mass univariate methods. The present study aimed to overcome the previous methodological limitations and to build a predictive model of narcissistic traits based on neural and psychological features. In this respect, two machine learning-based methods (Kernel Ridge Regression and Support Vector Regression) were used to predict narcissistic traits from brain structural organization and from …
Remimazolam – Current Status, Opportunities And Challenges, J. Robert Sneyd
Remimazolam – Current Status, Opportunities And Challenges, J. Robert Sneyd
More Faculty of Health Research
The short acting benzodiazepine remimazolam has been well characterised for use during procedural sedation. Onset of hypnotic effect is swifter than midazolam and recovery is faster with a period of antegrade amnesia. Haemodynamic changes associated with remimazolam sedation are modest and there is no pain on injection. General anaesthesia may be induced and maintained by infusion of remimazolam in combination with a suitable opioid. Hypotension is less frequent than when propofol is used. In addition, remimazolam may be a suitable alternative to propofol or etomidate for inducing anaesthesia in haemodynamically compromised patients prior to maintenance with a volatile agent. A …
A Narrow Band Of Image Dimensions Is Critical For Face Recognition, Timothy J. Andrews, Daniel Rogers, Mila Mileva, David M. Watson, Ao Wang, A. Mike Burton
A Narrow Band Of Image Dimensions Is Critical For Face Recognition, Timothy J. Andrews, Daniel Rogers, Mila Mileva, David M. Watson, Ao Wang, A. Mike Burton
School of Psychology
A key challenge in human and computer face recognition is to differentiate information that is diagnostic for identity from other sources of image variation. Here, we used a combined computational and behavioural approach to reveal critical image dimensions for face recognition. Behavioural data were collected using a sorting and matching task with unfamiliar faces and a recognition task with familiar faces. Principal components analysis was used to reveal the dimensions across which the shape and texture of faces in these tasks varied. We then asked which image dimensions were able to predict behavioural performance across these tasks. We found that …