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Mesophotic Coral Bleaching Associated With Changes In Thermocline Depth, Clara Diaz, Nicola L. Foster, Martin J. Attrill, Adam Bolton, Peter Ganderton, Kerry L. Howell, Edward Robinson, Phil Hosegood Oct 2023

Mesophotic Coral Bleaching Associated With Changes In Thermocline Depth, Clara Diaz, Nicola L. Foster, Martin J. Attrill, Adam Bolton, Peter Ganderton, Kerry L. Howell, Edward Robinson, Phil Hosegood

School of Biological and Marine Sciences

As global temperatures continue to rise, shallow coral reef bleaching has become more intense and widespread. Mesophotic coral ecosystems (30–150 m) reside in deeper, cooler, water and were thought to offer a refuge to shallow-water reefs. Data now show that mesophotic coral ecosystems instead have limited connectivity with shallow corals but host diverse endemic communities. Given their extensive distribution and high biodiversity, understanding their susceptibility to warming oceans is imperative. In this multidisciplinary study we show evidence of coral bleaching at 90 m in the Indian Ocean, despite the absence of shallow-water bleaching. The bleaching was associated with sustained thermocline …

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A Climate Perturbation At The Middle –Late Jurassic Transition? Evaluating The Isotopic Evidence From South-Central England, Gregory D. Price, Bernát Heszler, Charlton L-M Tansley, Jade Cox Oct 2023

A Climate Perturbation At The Middle –Late Jurassic Transition? Evaluating The Isotopic Evidence From South-Central England, Gregory D. Price, Bernát Heszler, Charlton L-M Tansley, Jade Cox

School of Geography, Earth and Environmental Sciences

No abstract provided.

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Metrics Matter: Multiple Diversity Metrics At Different Spatial Scales Are Needed To Understand Species Diversity In Urban Environments, Kathryn A. O'Shaughnessy, Antony M. Knights, Stephen J. Hawkins, Mick E. Hanley, Paul Lunt, Richard C. Thompson, Louise B. Firth Oct 2023

Metrics Matter: Multiple Diversity Metrics At Different Spatial Scales Are Needed To Understand Species Diversity In Urban Environments, Kathryn A. O'Shaughnessy, Antony M. Knights, Stephen J. Hawkins, Mick E. Hanley, Paul Lunt, Richard C. Thompson, Louise B. Firth

School of Biological and Marine Sciences

Worldwide, natural habitats are being replaced by artificial structures due to urbanisation. Planning of such modifications should strive for environmental net gain that benefits biodiversity and ecosystems. Alpha (α) and gamma (γ) diversity are often used to assess ‘impact’ but are insensitive metrics. We test several diversity measures across two spatial scales to compare species diversity in natural and artificial habitats. We show γ-diversity indicates equivalency in biodiversity between natural and artificial habitats, but natural habitats support greater taxon (α) and functional richness. Within-site β-diversity was also greater in natural habitats, but among-site β-diversity was greater in artificial habitats, contradicting …

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Learning And Gender In Everyday Life, Jocey Quinn Oct 2023

Learning And Gender In Everyday Life, Jocey Quinn

Plymouth Institute of Education

This paper focuses on the learning that happens in everyday life, beyond the formal learning environments of schools, colleges, and universities or even beyond community and adult education. It draws on posthuman concepts of ‘learning affect’ and ‘new worlds’ to conceptualise this as ‘invisible education’, affective and transformative, unrecognised but powerful and formative. Such invisible education has a powerful impact on formations of gender, class, race, sexuality, and disability and is thus a key field of enquiry with important consequences for gender equality. The paper will draw on a diverse range of grant funded qualitative, research projects to focus on …

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Towards A Scientific Community Consensus On Designating Vulnerable Marine Ecosystems From Imagery, Amy R. Baco, Rebecca Ross, Franziska Althaus, Diva Amon, Amelia E.H. Bridges, Saskia Brix, Pål Buhl-Mortensen, Ana Colaco, Marina Carreiro-Silva, Malcolm R. Clark, Preez C Du, Mari Lise Franken, Matthew Gianni, Genoveva Gonzalez-Mirelis, Thomas Hourigan, Kerry Howell, Lisa A. Levin, Dhugal J. Lindsay, Tina N. Molodtsova, Nicole Morgan, Telmo Morato, Beatriz E. Mejia-Mercado, D O’Sullivan, Tabitha Pearman, David Price, Katleen Robert, Laura Robson, Ashley A. Rowden, J Taylor, M Taylor, Lissette Victorero, Les Watling, Alan Williams, Joana R. Xavier, Chris Yesson Oct 2023

Towards A Scientific Community Consensus On Designating Vulnerable Marine Ecosystems From Imagery, Amy R. Baco, Rebecca Ross, Franziska Althaus, Diva Amon, Amelia E.H. Bridges, Saskia Brix, Pål Buhl-Mortensen, Ana Colaco, Marina Carreiro-Silva, Malcolm R. Clark, Preez C Du, Mari Lise Franken, Matthew Gianni, Genoveva Gonzalez-Mirelis, Thomas Hourigan, Kerry Howell, Lisa A. Levin, Dhugal J. Lindsay, Tina N. Molodtsova, Nicole Morgan, Telmo Morato, Beatriz E. Mejia-Mercado, D O’Sullivan, Tabitha Pearman, David Price, Katleen Robert, Laura Robson, Ashley A. Rowden, J Taylor, M Taylor, Lissette Victorero, Les Watling, Alan Williams, Joana R. Xavier, Chris Yesson

School of Biological and Marine Sciences

Management of deep-sea fisheries in areas beyond national jurisdiction by Regional Fisheries Management Organizations/Arrangements (RFMO/As) requires identification of areas with Vulnerable Marine Ecosystems (VMEs). Currently, fisheries data, including trawl and longline bycatch data, are used by many RFMO/As to inform the identification of VMEs. However, the collection of such data creates impacts and there is a need to collect non-invasive data for VME identification and monitoring purposes. Imagery data from scientific surveys satisfies this requirement, but there currently is no established framework for identifying VMEs from images. Thus, the goal of this study was to bring together a large international …

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Scoping Potential Routes To Uk Civil Unrest Via The Food System: Results Of A Structured Expert Elicitation, A Jones, S Bridle, K Denby, R Bhunoo, D Morton, L Stanborough, B Coupe, V Pilley, T Benton, P Faloon, T Matthews, C Pettinger Oct 2023

Scoping Potential Routes To Uk Civil Unrest Via The Food System: Results Of A Structured Expert Elicitation, A Jones, S Bridle, K Denby, R Bhunoo, D Morton, L Stanborough, B Coupe, V Pilley, T Benton, P Faloon, T Matthews, C Pettinger

School of Health Professions

We report the results of a structured expert elicitation to identify the most likely types of potential food system disruption scenarios for the UK, focusing on routes to civil unrest. We take a backcasting approach by defining as an end-point a societal event in which 1 in 2000 people have been injured in the UK, which 40% of experts rated as “Possible (20–50%)”, “More likely than not (50–80%)” or “Very likely (>80%)” over the coming decade. Over a timeframe of 50 years, this increased to 80% of experts. The experts considered two food system scenarios and ranked their plausibility …

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Blood Biomarker-Based Classification Study For Neurodegenerative Diseases, Jack Kelly, Rana Moyeed, Camille Carroll, Shouqing Luo, Xinzhong Li Oct 2023

Blood Biomarker-Based Classification Study For Neurodegenerative Diseases, Jack Kelly, Rana Moyeed, Camille Carroll, Shouqing Luo, Xinzhong Li

Peninsula Medical School

As the population ages, neurodegenerative diseases are becoming more prevalent, making it crucial to comprehend the underlying disease mechanisms and identify biomarkers to allow for early diagnosis and effective screening for clinical trials. Thanks to advancements in gene expression profiling, it is now possible to search for disease biomarkers on an unprecedented scale.Here we applied a selection of five machine learning (ML) approaches to identify blood-based biomarkers for Alzheimer's (AD) and Parkinson's disease (PD) with the application of multiple feature selection methods. Based on ROC AUC performance, one optimal random forest (RF) model was discovered for AD with 159 gene …

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High Throughput Laser Ablation Icp-Ms Bioimaging Of Silver Distribution In Animal Organisms And Plant Tissue After Exposure To Silver Sulfide Nanoparticles, G Marolt, S Novak, Aj Kokalj, I Talaber, V Kononenko, S Loureiro, Z Khodaparast, Pv Silva, Mb Fité, Rd Handy, D Drobne Oct 2023

High Throughput Laser Ablation Icp-Ms Bioimaging Of Silver Distribution In Animal Organisms And Plant Tissue After Exposure To Silver Sulfide Nanoparticles, G Marolt, S Novak, Aj Kokalj, I Talaber, V Kononenko, S Loureiro, Z Khodaparast, Pv Silva, Mb Fité, Rd Handy, D Drobne

School of Biological and Marine Sciences

Laser ablation inductively coupled plasma mass spectrometry (LA-ICP-MS) is a method with high potential to visualize the distribution of elements in different samples, including a variety of organisms. This study aimed to demonstrate the broad application of LA-ICP-MS in nanomaterial-biota fate studies as a high throughput bioimaging tool and to broaden the choice of standard organism models in material-biota interaction research. In this study, operation parameters of LA-ICP-MS were optimised on one organism, woodlice Porcellio scaber. Subsequently, the scanning conditions were tested on a range of aquatic (Girardia tigrina, Lumbriculus variegatus, and Oncorhynchus mykiss), terrestrial organisms (Lumbricus rubellus, Porcellio scaber) …

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Zinc Oxide Nanoparticles Disrupt Development And Function Of The Olfactory Sensory System Impairing Olfaction-Mediated Behaviour In Zebrafish, Aya Takesono, Sylvia Dimitriadou, Nathaniel J. Clark, Richard D. Handy, Sulayman Mourabit, Matthew J. Winter, Tetsuhiro Kudoh, Charles R. Tyler Oct 2023

Zinc Oxide Nanoparticles Disrupt Development And Function Of The Olfactory Sensory System Impairing Olfaction-Mediated Behaviour In Zebrafish, Aya Takesono, Sylvia Dimitriadou, Nathaniel J. Clark, Richard D. Handy, Sulayman Mourabit, Matthew J. Winter, Tetsuhiro Kudoh, Charles R. Tyler

School of Health Professions

Zinc (Zn) is an essential metal present in numerous enzymes throughout the body, playing a vital role in animal and human health. However, the increasing use of zinc oxide nanomaterials (ZnONPs) in a diverse range of products has raised concerns regarding their potential impacts on health and the environment. Despite these concerns, the toxicity of ZnONP exposure on animal health remain poorly understood. To help address this knowledge gap, we have developed a highly sensitive oxidative stress (OS) biosensor zebrafish capable of detecting cell/tissue-specific OS responses to low doses of various oxidative stressors, including Zn, in a live fish embryo. …

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The Colonisation Of The Tyrrhenian Islands By Hydraena Water Beetles, With Hydraena Reflexa Rey, 1884 Reinstated As A Valid Species Endemic To Corsica And Sardinia (Coleoptera, Hydraenidae), David T. Bilton, Ignacio Ribera, Adrián Villastrigo Oct 2023

The Colonisation Of The Tyrrhenian Islands By Hydraena Water Beetles, With Hydraena Reflexa Rey, 1884 Reinstated As A Valid Species Endemic To Corsica And Sardinia (Coleoptera, Hydraenidae), David T. Bilton, Ignacio Ribera, Adrián Villastrigo

School of Biological and Marine Sciences

The biotas of old islands formed from continental terranes usually have a more complex biogeographical history than those of young oceanic islands, including taxa which have originated by vicariance and/or colonisation, over a variety of timescales. The Tyrrhenian Islands of Corsica, Sardinia and the Tuscan Archipelago in the Mediterranean have a complex geological history, shaped by interac-tions between the African and Eurasian plates since the Mesozoic. Our understanding of the historical biogeography of Tyrrhenian endemics remains limited for many groups, including freshwater invertebrates. Here we use a time-calibrated phylogeny, derived from mitochondrial and nuclear DNA sequence data, to explore the …

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Reiterated Empathy In Ba Director Training, Alex Cahill Oct 2023

Reiterated Empathy In Ba Director Training, Alex Cahill

School of Art, Design and Architecture

In 2019, the University of Plymouth started the only current BA Directing degree program in the United Kingdom. As programme creator/lead and curriculum designer, I was interviewed in 2021 by The Stage to discuss whether the craft of directing can be taught in a classroom. While some may argue the ‘director’s eye (that is – the mental ability to coherently visualise the whole production) cannot be taught, I argue that directing skills, specifically collaboration skills through reiterated empathy, can both be taught and should also be the basis of director training. Therefore, I created a series of exercises based on …

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Light And Temperature Drive The Distribution Of Mesophotic Benthic Communities In The Central Indian Ocean, Clara Diaz, Kerry L. Howell, Edward Robinson, Philip Hosegood, Adam Bolton, Peter Ganderton, Peter Arber, Martin J. Attrill, Nicola L. Foster Oct 2023

Light And Temperature Drive The Distribution Of Mesophotic Benthic Communities In The Central Indian Ocean, Clara Diaz, Kerry L. Howell, Edward Robinson, Philip Hosegood, Adam Bolton, Peter Ganderton, Peter Arber, Martin J. Attrill, Nicola L. Foster

School of Biological and Marine Sciences

Aim Research on mesophotic coral ecosystems (MCEs) has increased exponentially in recent decades, and the significance of this ecosystem has been recognised both in terms of biodiversity and distribution. However, this research has mostly focussed on corals and is globally sporadic, with the Indian Ocean remaining largely unexplored and overall MCEs under protected. Hence, baseline data on MCE benthic communities is lacking, but nonetheless essential for developing adequate management strategies. Here, we assess the variation in diversity and community structure of MCEs along the depth gradient and among sites in the Indian Ocean and the environmental parameters that are potentially …

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Dynamical Oceanographic Processes Impact On Reef Manta Ray Behaviour: Extreme Indian Ocean Dipole Influence On Local Internal Wave Dynamics At A Remote Tropical Atoll, Edward Robinson, Phil Hosegood, Adam Bolton Oct 2023

Dynamical Oceanographic Processes Impact On Reef Manta Ray Behaviour: Extreme Indian Ocean Dipole Influence On Local Internal Wave Dynamics At A Remote Tropical Atoll, Edward Robinson, Phil Hosegood, Adam Bolton

School of Biological and Marine Sciences

Physical oceanographic observations were made with subsurface, taut-line moorings at Egmont Island, a tropical atoll within the Chagos Archipelago in the central Indian Ocean, to elucidate the dynamics of near-bed cold-water intrusions implicated in driving local aggregations of reef manta rays (Mobula alfredi). Manta have been previously shown to aggregate within ‘Manta Alley’, a lipped gully at 65 m depth along the north coast, at times when the surface to bottom temperature difference was highest. We here identify the dynamical processes driving these temperature differences and shaping the foraging landscape at Egmont, and equivalent small-scale atolls, improving our understanding of …

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Functional Behaviour Of Flocs Explained By Observed 3d Structure And Porosity, Tj Lawrence, Sj Carr, Aj Manning, Jat Wheatland, Aj Bushby, Kl Spencer Oct 2023

Functional Behaviour Of Flocs Explained By Observed 3d Structure And Porosity, Tj Lawrence, Sj Carr, Aj Manning, Jat Wheatland, Aj Bushby, Kl Spencer

School of Biological and Marine Sciences

Clay-rich flocculated suspended sediments are an important constituent of estuarine and coastal systems globally. They are responsible for the host, movement and deposition of a variety of pollutants, contaminants and sediment itself. Accurate modelling of the movement of these sediments is crucial for a number of industries including fisheries, aquaculture, shipping and waste management. This requires an accurate and reliable measurements of the physical properties of flocs and their behaviour. Porosity is a key element in floc structures, and this research provides updated 3D quantified porosity and pore space morphological data in relation to influences on floc settling behaviour. We …

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Effectiveness Of Out-Patient Based Acute Heart Failure Care: A Pilot Randomised Controlled Trial, Kyk Wong, D. A. Hughes, M. Debski, N. Latt, O. Assaf, A. Abdelrahman, R. Taylor, V. Allgar, L. Mcneill, S. Howard, Sys Wong, R. Jones, C. J. Cassidy, A. Seed, G. Galasko, A. Clark, D. Wilson, G. K. Davis, A. Montasem, C. C. Lang, P. R. Kalra, R. Campbell, G. Y.H. Lip, J. G.F. Cleland Oct 2023

Effectiveness Of Out-Patient Based Acute Heart Failure Care: A Pilot Randomised Controlled Trial, Kyk Wong, D. A. Hughes, M. Debski, N. Latt, O. Assaf, A. Abdelrahman, R. Taylor, V. Allgar, L. Mcneill, S. Howard, Sys Wong, R. Jones, C. J. Cassidy, A. Seed, G. Galasko, A. Clark, D. Wilson, G. K. Davis, A. Montasem, C. C. Lang, P. R. Kalra, R. Campbell, G. Y.H. Lip, J. G.F. Cleland

Peninsula Medical School

Objectives Acute heart failure (AHF) hospitalisation is associated with 10% mortality. Outpatient based management (OPM) of AHF appeared effective in observational studies. We conducted a pilot randomised controlled trial (RCT) comparing OPM with standard inpatient care (IPM). Methods We randomised patients with AHF, considered to need IV diuretic treatment for ≥2 days, to IPM or OPM. We recorded all-cause mortality, and the number of days alive and out-of-hospital (DAOH). Quality of life, mental well-being and Hope scores were assessed. Mean NHS cost savings and 95% central range (CR) were calculated from bootstrap analysis. Follow-up: 60 days. Results Eleven patients were …

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Inner Development Goals And The Meaning, Awareness And Purpose (Map) Model For Climate Coaching, J Rhodes, J Blakeley-Glover, A Miller, A Taylor, I Rochmankowski Oct 2023

Inner Development Goals And The Meaning, Awareness And Purpose (Map) Model For Climate Coaching, J Rhodes, J Blakeley-Glover, A Miller, A Taylor, I Rochmankowski

School of Psychology

In the initial study, two focus groups (n=11) scrutinized the five domains within the Inner Development Goals (IDG) framework, examining the essential skills for tackling challenging goals. They collaboratively crafted a streamlined 29-item measure (IDG-A), incorporating a novel sixth domain: organizational belonging. The second study assessed the IDG-A among employees from four organizations (n=39), exploring correlations between the 29 items, six domains, and overall scores. Significantly, many items, nearly all domains, and all domains in relation to the composite score exhibited meaningful correlations, suggesting strong single conceptual alignment. The third study employed findings from the first, leveraging the conceptual congruence …

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Calculation Of Atp Production Rates Using The Seahorse Xf Analyzer, Brandon R. Desousa, Kristen K.O. Kim, Anthony E. Jones, Andréa B. Ball, Wei Y. Hsieh, Pamela Swain, Danielle H. Morrow, Alexandra J. Brownstein, David A. Ferrick, Orian S. Shirihai, Andrew Neilson, David A. Nathanson, George W. Rogers, Brian P. Dranka, Anne N. Murphy, Charles Affourtit, Steven J. Bensinger, Linsey Stiles, Natalia Romero, Ajit S. Divakaruni Oct 2023

Calculation Of Atp Production Rates Using The Seahorse Xf Analyzer, Brandon R. Desousa, Kristen K.O. Kim, Anthony E. Jones, Andréa B. Ball, Wei Y. Hsieh, Pamela Swain, Danielle H. Morrow, Alexandra J. Brownstein, David A. Ferrick, Orian S. Shirihai, Andrew Neilson, David A. Nathanson, George W. Rogers, Brian P. Dranka, Anne N. Murphy, Charles Affourtit, Steven J. Bensinger, Linsey Stiles, Natalia Romero, Ajit S. Divakaruni

School of Biomedical Sciences

Oxidative phosphorylation and glycolysis are the dominant ATP-generating pathways in mammalian metabolism. The balance between these two pathways is often shifted to execute cell-specific functions in response to stimuli that promote activation, proliferation, or differentiation. However, measurement of these metabolic switches has remained mostly qualitative, making it difficult to discriminate between healthy, physiological changes in energy transduction or compensatory responses due to metabolic dysfunction. We therefore present a broadly applicable method to calculate ATP production rates from oxidative phosphorylation and glycolysis using Seahorse XF Analyzer data and empirical conversion factors. We quantify the bioenergetic changes observed during macrophage polarization as …

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Energy, Passivity, And Morphological Capacities, Pablo Borja, Cosimo Della Santina, Azita Dabiri Oct 2023

Energy, Passivity, And Morphological Capacities, Pablo Borja, Cosimo Della Santina, Azita Dabiri

School of Engineering, Computing and Mathematics

The morphology of a system may be exploited to reduce the controller workload or to perform specific tasks, e.g., locomotion processes. However, understanding and characterizing these capacities in terms of physical quantities remains an open problem. In this paper, we pose the question: are energy and dissipation useful physical quantities to characterize morphological capacities? First, to illustrate the relevance of this question, we present some basic concepts of passivity theory that are useful for carrying out an energy-based analysis of the behavior of dynamical systems. Then, we analyze the behavior of a mechanical system, and we show how its morphology …

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Kernel Density Estimation Of Conditional Distributions To Detect Responses In Satellite Tag Data, Joshua Hewitt, Alan E. Gelfand, Nicola J. Quick, William R. Cioffi, Brandon L. Southall, Stacy L. Deruiter, Robert S. Schick Sep 2023

Kernel Density Estimation Of Conditional Distributions To Detect Responses In Satellite Tag Data, Joshua Hewitt, Alan E. Gelfand, Nicola J. Quick, William R. Cioffi, Brandon L. Southall, Stacy L. Deruiter, Robert S. Schick

School of Biological and Marine Sciences

Background As levels of anthropogenic noise in the marine environment rise, it is crucial to quantify potential associated effects on marine mammals. Yet measuring responses is challenging because most species spend the majority of their time submerged. Consequently, much of their sub-surface behavior is difficult or impossible to observe and it can be difficult to determine if—during or following an exposure to sound—an observed dive differs from previously recorded dives. We propose a method for initial assessment of potential behavioral responses observed during controlled exposure experiments (CEEs), in which animals are intentionally exposed to anthropogenic sound sources. To identify possible …

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Machine Learning In Marine Ecology: An Overview Of Techniques And Applications, Peter Rubbens, Stephanie Brodie, Tristan Cordier, D Destro Barcellos, Paul Devos, Jose A. Fernandes-Salvador, Jennifer I. Fincham, Alessandra Gomes, Nils Olav Handegard, Kerry Howell, Cédric Jamet, Kyrre Heldal Kartveit, Hassan Moustahfid, Clea Parcerisas, Dimitris Politikos, Raphaëlle Sauzède, Maria Sokolova, Laura Uusitalo, L Van Den Bulcke, Atm Van Helmond, Jordan T. Watson, Heather Welch, Oscar Beltran-Perez, Samuel Chaffron, David S. Greenberg, Bernhard Kühn, Rainer Kiko, Madiop Lo, Rubens M. Lopes, Rubens M. Lopes, William Michaels, Ahmet Pala, Jean Baptiste Romagnan, Pia Schuchert, Vahid Seydi, Sebastian Villasante, Ketil Malde, Jean Olivier Irisson Sep 2023

Machine Learning In Marine Ecology: An Overview Of Techniques And Applications, Peter Rubbens, Stephanie Brodie, Tristan Cordier, D Destro Barcellos, Paul Devos, Jose A. Fernandes-Salvador, Jennifer I. Fincham, Alessandra Gomes, Nils Olav Handegard, Kerry Howell, Cédric Jamet, Kyrre Heldal Kartveit, Hassan Moustahfid, Clea Parcerisas, Dimitris Politikos, Raphaëlle Sauzède, Maria Sokolova, Laura Uusitalo, L Van Den Bulcke, Atm Van Helmond, Jordan T. Watson, Heather Welch, Oscar Beltran-Perez, Samuel Chaffron, David S. Greenberg, Bernhard Kühn, Rainer Kiko, Madiop Lo, Rubens M. Lopes, Rubens M. Lopes, William Michaels, Ahmet Pala, Jean Baptiste Romagnan, Pia Schuchert, Vahid Seydi, Sebastian Villasante, Ketil Malde, Jean Olivier Irisson

School of Biological and Marine Sciences

Machine learning covers a large set of algorithms that can be trained to identify patterns in data. Thanks to the increase in the amount of data and computing power available, it has become pervasive across scientific disciplines. We first highlight why machine learning is needed in marine ecology. Then we provide a quick primer on machine learning techniques and vocabulary. We built a database of ∼1000 publications that implement such techniques to analyse marine ecology data. For various data types (images, optical spectra, acoustics, omics, geolocations, biogeochemical profiles, and satellite imagery), we present a historical perspective on applications that proved …

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Poetry And Covid-19: The Benefit Of Poetry And The Poetryandcovidarchive.Com Website To Mental Health And Wellbeing, Anthony Caleshu, Rory Waterman, Sam Kemp Sep 2023

Poetry And Covid-19: The Benefit Of Poetry And The Poetryandcovidarchive.Com Website To Mental Health And Wellbeing, Anthony Caleshu, Rory Waterman, Sam Kemp

School of Law, Humanities and Social Sciences

From June 2020 to June 2021, the website poetryandcovid.com (now archived as poetryandcovidarchive.com) served as a platform for poetic responses by people from around the world to the COVID-19 pandemic. The site featured 1000+ poems by 600+ poets and received c. 100,000 views by people from 128 countries. The poetry, their author’s testimonials, as well as “comments” submitted to the organisers and public website, expressed how people felt during the pandemic. In the project’s final three months, the website hosted a survey adapted from the Warwick-Edinburgh Mental Well-being Scale (WEMWBS), targeted at understanding the value of poetry, in general, and …

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Hygrothermal And Economic Analysis Of An Earth-Based Building Using In Situ Investigations And Artificial Neural Network Modeling For Normandy’S Climate Conditions, K Touati, M-H Benzaama, Mendili Y El, Guern M Le, F Streiff, S Goodhew Sep 2023

Hygrothermal And Economic Analysis Of An Earth-Based Building Using In Situ Investigations And Artificial Neural Network Modeling For Normandy’S Climate Conditions, K Touati, M-H Benzaama, Mendili Y El, Guern M Le, F Streiff, S Goodhew

School of Art, Design and Architecture

This paper investigates the in situ hygrothermal behavior of a cob prototype building equipped with multiple sensors for measuring temperature, relative humidity inside the building, and water content within its walls. The experimental results show that the earth-based prototype building presents interesting thermal insulation performance. Without any heating system, the indoor temperature was found to remain stable, near 20 °C, despite large fluctuations in the outdoor temperature. This study also illustrated the ability of cob to absorb and regulate indoor relative humidity. The use of a neural network model for predicting the hygrothermal behavior of the cob prototype building was …

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Levelling-Up Rhodolith-Bed Science To Address Global-Scale Conservation Challenges, Fernando Tuya, Nadine Schubert, Julio Aguirre, Daniela Basso, Eduardo O. Bastos, Flávio Berchez, Angelo F. Bernardino, Néstor E. Bosch, Heidi L. Burdett, Fernando Espino, Cindy Fernández-Gárcia, Ronaldo B. Francini-Filho, Patrick Gagnon, Jason M. Hall-Spencer, Ricardo Haroun, Laurie C. Hofmann, Paulo A. Horta, Nicholas A. Kamenos, Gall L Le, Rafael A. Magris, Sophie Martin, Wendy A. Nelson, Pedro Neves, Irene Olivé, Francisco Otero-Ferrer, Viviana Peña, Guilherme H. Pereira-Filho, Federica Ragazzola, Ana Cristina Rebelo, Cláudia Ribeiro, Eli Rinde, Kathryn Schoenrock, João Silva, Marina N. Sissini, Frederico T.S. Tâmega Sep 2023

Levelling-Up Rhodolith-Bed Science To Address Global-Scale Conservation Challenges, Fernando Tuya, Nadine Schubert, Julio Aguirre, Daniela Basso, Eduardo O. Bastos, Flávio Berchez, Angelo F. Bernardino, Néstor E. Bosch, Heidi L. Burdett, Fernando Espino, Cindy Fernández-Gárcia, Ronaldo B. Francini-Filho, Patrick Gagnon, Jason M. Hall-Spencer, Ricardo Haroun, Laurie C. Hofmann, Paulo A. Horta, Nicholas A. Kamenos, Gall L Le, Rafael A. Magris, Sophie Martin, Wendy A. Nelson, Pedro Neves, Irene Olivé, Francisco Otero-Ferrer, Viviana Peña, Guilherme H. Pereira-Filho, Federica Ragazzola, Ana Cristina Rebelo, Cláudia Ribeiro, Eli Rinde, Kathryn Schoenrock, João Silva, Marina N. Sissini, Frederico T.S. Tâmega

School of Biological and Marine Sciences

Global marine conservation remains fractured by an imbalance in research efforts and policy actions, limiting progression towards sustainability. Rhodolith beds represent a prime example, as they have ecological importance on a global scale, provide a wealth of ecosystem functions and services, including biodiversity provision and potential climate change mitigation, but remain disproportionately understudied, compared to other coastal ecosystems (tropical coral reefs, kelp forests, mangroves, seagrasses). Although rhodolith beds have gained some recognition, as important and sensitive habitats at national/regional levels during the last decade, there is still a notable lack of information and, consequently, specific conservation efforts. We argue that …

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Physical And Chemical Effects Of Conventional Microplastic Glitter Versus Alternative Glitter Particles On A Freshwater Plant (Lemnaceae: Lemna Minor), Bas Boots, Dannielle Senga Green, Brigitta Olah-Kovacs, Falco F De, Emanuele Lupo Sep 2023

Physical And Chemical Effects Of Conventional Microplastic Glitter Versus Alternative Glitter Particles On A Freshwater Plant (Lemnaceae: Lemna Minor), Bas Boots, Dannielle Senga Green, Brigitta Olah-Kovacs, Falco F De, Emanuele Lupo

School of Geography, Earth and Environmental Sciences

Glitters are primary microplastics which are directly littered into the environment, yet the ecological effects have seldom been tested. When microplastics enter the environment, their physical presence and chemical leachate may alter the physiology of primary producers. Glitter can be composed of plastic or natural and/or biodegradable materials, often with additives. Three experiments were run for 14 days to separate chemical and physical effects of different types of glitter: polyethylene terephthalate (PET), biodegradable modified regenerated cellulose (MRC), synthetic mica, and a natural particle control (kaolinite) on several physical characteristics of Lemna minor (common duckweed). L. minor was exposed to either …

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Author Correction: Elucidating Causative Gene Variants In Hereditary Parkinson’S Disease In The Global Parkinson’S Genetics Program (Gp2), Lara M. Lange, Micol Avenali, Melina Ellis, Anastasia Illarionova, Sarmiento Ij Keller, Ai Huey Tan, Harutyun Madoev, Caterina Galandra, Johanna Junker, Karisha Roopnarain, Justin Solle, Claire Wegel, Zih Hua Fang, Peter Heutink, Kishore R. Kumar, Shen Yang Lim, Enza Maria Valente, Mike Nalls, Cornelis Blauwendraat, Andrew Singleton, Niccolo Mencacci, Katja Lohmann, Christine Klein, Emilia M. Gatto, Marcelo Kauffman, Samson Khachatryan, Zaruhi Tavadyan, Claire E. Shepherd, Julie Hunter, Miguel E. Rentería Sep 2023

Author Correction: Elucidating Causative Gene Variants In Hereditary Parkinson’S Disease In The Global Parkinson’S Genetics Program (Gp2), Lara M. Lange, Micol Avenali, Melina Ellis, Anastasia Illarionova, Sarmiento Ij Keller, Ai Huey Tan, Harutyun Madoev, Caterina Galandra, Johanna Junker, Karisha Roopnarain, Justin Solle, Claire Wegel, Zih Hua Fang, Peter Heutink, Kishore R. Kumar, Shen Yang Lim, Enza Maria Valente, Mike Nalls, Cornelis Blauwendraat, Andrew Singleton, Niccolo Mencacci, Katja Lohmann, Christine Klein, Emilia M. Gatto, Marcelo Kauffman, Samson Khachatryan, Zaruhi Tavadyan, Claire E. Shepherd, Julie Hunter, Miguel E. Rentería

Peninsula Medical School

Correction to: s41531-023-00526-9 npj Parkinson’s Disease, published online 27 June 2023 In this article the Global Parkinson’s Genetics Program (GP2) members names and affiliations were missing in the main author list of the Original article which are listed in the below.

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Implicit Body Perception At The Pelvic Girdle With The Two-Point Estimation Task: A Reliability Study, B Halliday, J Freeman, S Chatfield, J Marsden Sep 2023

Implicit Body Perception At The Pelvic Girdle With The Two-Point Estimation Task: A Reliability Study, B Halliday, J Freeman, S Chatfield, J Marsden

School of Health Professions

Background & aims: Implicit body perception disturbance has been evidenced in low back pain (LBP) using the two-point estimation (2PE) measure. Previous research has only investigated unilateral LBP, not included a pain-free control group, or examined the measure at the pelvic girdle. Aims 1) design a testing protocol suitable for assessing pain crossing the midline (central) 2) investigate regional 2PE reliability 3) compare left and right sides and lumbar and pelvic regions. Methods: A central 2PE measure was designed and protocolised. Non-pregnant, pain-free adult women > 18 years old were recruited from a university setting. Participants were assessed with repeated 2PE …

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Defining The Causes Of Sporadic Parkinson’S Disease In The Global Parkinson’S Genetics Program (Gp2), Clodagh Towns, Madeleine Richer, Simona Jasaityte, Eleanor J. Stafford, Julie Joubert, Tarek Antar, Alejandro Martinez-Carrasco, Mary B. Makarious, Bradford Casey, Dan Vitale, K Levine, Hampton Leonard, Caroline B. Pantazis, La Screven, Dg Hernandez, Ce Wegel, J Solle, Mike A. Nalls, Cornelis Blauwendraat, Andrew B. Singleton, Mmx Tan, Hirotaka Iwaki, Huw R. Morris, Emilia M. Gatto, Marcelo Kauffman, Samson Khachatryan, Zaruhi Tavadyan, Claire E. Shepherd, Julie Hunter, Kishore Kumar Sep 2023

Defining The Causes Of Sporadic Parkinson’S Disease In The Global Parkinson’S Genetics Program (Gp2), Clodagh Towns, Madeleine Richer, Simona Jasaityte, Eleanor J. Stafford, Julie Joubert, Tarek Antar, Alejandro Martinez-Carrasco, Mary B. Makarious, Bradford Casey, Dan Vitale, K Levine, Hampton Leonard, Caroline B. Pantazis, La Screven, Dg Hernandez, Ce Wegel, J Solle, Mike A. Nalls, Cornelis Blauwendraat, Andrew B. Singleton, Mmx Tan, Hirotaka Iwaki, Huw R. Morris, Emilia M. Gatto, Marcelo Kauffman, Samson Khachatryan, Zaruhi Tavadyan, Claire E. Shepherd, Julie Hunter, Kishore Kumar

Peninsula Medical School

The Global Parkinson’s Genetics Program (GP2) will genotype over 150,000 participants from around the world, and integrate genetic and clinical data for use in large-scale analyses to dramatically expand our understanding of the genetic architecture of PD. This report details the workflow for cohort integration into the complex arm of GP2, and together with our outline of the monogenic hub in a companion paper, provides a generalizable blueprint for establishing large scale collaborative research consortia.

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A Magneto-Activated Nanoscale Cytometry Platform For Molecular Profiling Of Small Extracellular Vesicles, Kangfu Chen, Bill T.V. Duong, Sharif U. Ahmed, Piriththiv Dhavarasa, Z Wang, Mahmoud Labib, Connor Flynn, Jingya Xu, Yi Y. Zhang, H Wang, Xiaolong Yang, Jagotamoy Das, Hossein Zargartalebi, Yuan Ma, Shana O. Kelley Sep 2023

A Magneto-Activated Nanoscale Cytometry Platform For Molecular Profiling Of Small Extracellular Vesicles, Kangfu Chen, Bill T.V. Duong, Sharif U. Ahmed, Piriththiv Dhavarasa, Z Wang, Mahmoud Labib, Connor Flynn, Jingya Xu, Yi Y. Zhang, H Wang, Xiaolong Yang, Jagotamoy Das, Hossein Zargartalebi, Yuan Ma, Shana O. Kelley

Peninsula Medical School

Exosomal PD-L1 (exoPD-L1) has recently received significant attention as a biomarker predicting immunotherapeutic responses involving the PD1/PD-L1 pathway. However, current technologies for exosomal analysis rely primarily on bulk measurements that do not consider the heterogeneity found within exosomal subpopulations. Here, we present a nanoscale cytometry platform NanoEPIC, enabling phenotypic sorting and exoPD-L1 profiling from blood plasma. We highlight the efficacy of NanoEPIC in monitoring anti-PD-1 immunotherapy through the interrogation of exoPD-L1. NanoEPIC generates signature exoPD-L1 patterns in responders and non-responders. In mice treated with PD1-targeted immunotherapy, exoPD-L1 is correlated with tumor growth, PD-L1 burden in tumors, and the immune suppression …

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De Novo Transcriptome Analysis Of Solanum Lycopersicum Cv. Super Strain B Under Drought Stress, Hassan S. Al-Zahrani, Tarek A.A. Moussa, Hameed Alsamadany, Rehab M. Hafez, Michael P. Fuller Sep 2023

De Novo Transcriptome Analysis Of Solanum Lycopersicum Cv. Super Strain B Under Drought Stress, Hassan S. Al-Zahrani, Tarek A.A. Moussa, Hameed Alsamadany, Rehab M. Hafez, Michael P. Fuller

School of Biological and Marine Sciences

Tomato cv. super strain B was widely cultivated in Saudi Arabia under drought stress. Illumina Hiseq-2000 was used to create the transcriptional profile of tomato cultivar super strain B. A total of 98,069 contigs were gathered, with an average length of 766 bp. Most of the genes in the gene ontology (GO) analysis were categorized into molecular function (MF) of ATP binding (1301 genes), metal ion binding (456 genes), protein kinase activity (392 genes), transferase activity (299 genes), Biological process (BP) of DNA-templated genes (366 genes), and regulation of transcription genes (209 genes), while cellular components (CC) of integral component …

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Out Of The Palaearctic: The Helophorus Water Beetles Of The Afrotropical Region (Coleoptera: Helophoridae), David T. Bilton Sep 2023

Out Of The Palaearctic: The Helophorus Water Beetles Of The Afrotropical Region (Coleoptera: Helophoridae), David T. Bilton

School of Biological and Marine Sciences

Helophorus Fabricius, 1775 (Coleoptera: Hydrophiloidea: Helophoridae) is an old and largely Holarctic genus of beetles, with most extant diversity concentrated in the Palae­arctic. As with a number of primarily northern temperate lineages, the genus has colonised the Afrotropical Region, with species described from the Ethiopian Highlands and southern Africa. Here, the Afrotropical Helophorus fauna is revised, based on a study of all primary types and additional material, including extensive recent collections from South Africa. The known Afrotropical fauna is shown to be comprised of six species, only three of which were previously described: H. aethiopicus Régimbart, 1907, from southern highland …

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