Digital Commons Network^™

Building The Path To Early Alzheimer's Prediction Using Machine Learning, Kincaid Rowbotham, Ling Li, Xusheng Wang

Arts & Sciences Undergraduate Showcase

Alzheimer’s disease (AD) is the most common form of dementia and one of the most prominent challenges of precision healthcare is early identification of AD. To combat this latency in diagnosis, integration of machine learning has been exercised for more cost efficient and powerful diagnostic tools. Specifically, we have developed a workflow for identifying AD within a given sample. Utilizing cerebral cortex proteomic data as a baseline, we were able to test two different forms of feature selection and 6 different machine learning methods. The best performing of these combinations was using a Support Vector Machine (SVM) method with features …

A Guide To Everlasting, Jona L. Pedersen

Floodwall Magazine

No abstract provided.

Long Haulers: The Us Airline Industry And Moving Forward From The Covid-19 Pandemic, James Norman

Aviation Faculty Publications

No abstract provided.

Swallow's Nest: Birdwatching Poems, Karissa Wehri

Greenway Press Chapbooks

No abstract provided.

The Year Of Brood Viii, Jona L. Pederson

Greenway Press Chapbooks

No abstract provided.

December 2, 2021: Agenda, University Of North Dakota

University Senate Meeting Minutes

Agenda for the December 2, 2021, meeting of the University Senate. 41 pages

November 4, 2021: Agenda, University Of North Dakota

University Senate Meeting Minutes

Agenda for the November 4, 2021, meeting of the University Senate. 15 pages

Development Of Alveolar-Capillary-Exchange (Ace) Chip And Its Application For Assessment Of Pm2.5-Induced Toxicity, Mingyang Gang, Song Tang, Haiyun Chang, Yuanyuan Chen, Fengge Chen, Ying Mu, Dong Zhao, Weiwei Fan, Huifang Tian, Diane Darland, Ying Zhang

Biology Faculty Publications

Although standard two-dimensional (2D) cell culture is an effective tool for cell studies, monolayer cultivation can yield imperfect or misleading information about numerous biological functions. In this study, we developed an alveolar-capillary exchange (ACE) chip aiming to simulate the cellular microenvironment at the alveolar-capillary interface. The ACE chip was designed with two chambers for culturing alveolar epithelial cells and vascular endothelial cells separately, which are separated by a microporous polycarbonate film that allows for the exchange of soluble biomolecules. Using this model, we further tested the toxic effects of fine particulate matter (PM2.5), a form of airborne pollutant known to …

Receiver Apprehension & Listener Style Retention, Karlene T. Clark

Librarian Posters and Presentations

Receiver apprehension is the anxiety patrons feel when approaching someone for help. There are different types of ways in which people process information, some of which can be a detriment to the person hoping to learn something or just have a question answered. This presentation looks at the different styles of listeners and how librarians can utilize this knowledge to better meet the needs of patrons coming to the reference desk for assistance.

Ebb Tide, Jenna B. Morgan

Floodwall Magazine

No abstract provided.

Autumn, In Grand Forks, Grant Macmillan

Floodwall Magazine

This brief photo-text collection aims to meld the visual and textual into a poetic expression of one person's experience of Autumn in Grand Forks. The photos and poems herein are meant to reflect and explicate each other—each component is simultaneously supplemental and integral to the other. Place is at the center of the collection. Whether the subject at hand is the impending extinction of a species or instructions on how to bake squash muffins with friends, each piece is inextricable from the writer's new home: Grand Forks, North Dakota.

Zoomsona, Jona L. Pedersen

Floodwall Magazine

No abstract provided.

Matchstick Keeper, Jona L. Pedersen

Floodwall Magazine

No abstract provided.

Weather Vane, Jona L. Pedersen

Floodwall Magazine

No abstract provided.

At The End Of The Path, Jona Pedersen, Wyatt Atchley

Floodwall Magazine

No abstract provided.

Contributor Notes

Floodwall Magazine

No abstract provided.

Writing Prompts On The Special Theme: Growth

Floodwall Magazine

No abstract provided.

An Entomologist’S Love Letter, Jona L. Pedersen

Floodwall Magazine

No abstract provided.

Developmental Programming Of Dna Methylation And Gene Expression Patterns Is Associated With Extreme Cardiovascular Tolerance To Anoxia In The Common Snapping Turtle, Ilan Ruhr, Jacob Bierstedt, Turk Rhen, Debojyoti Das, Sunil Kumar Singh, Soleille Miller, Dane A. Crossley Ii, Gina L. J. Galli

Biology Faculty Publications

Background

Environmental fluctuation during embryonic and fetal development can permanently alter an organism’s morphology, physiology, and behaviour. This phenomenon, known as developmental plasticity, is particularly relevant to reptiles that develop in subterranean nests with variable oxygen tensions. Previous work has shown hypoxia permanently alters the cardiovascular system of snapping turtles and may improve cardiac anoxia tolerance later in life. The mechanisms driving this process are unknown but may involve epigenetic regulation of gene expression via DNA methylation. To test this hypothesis, we assessed in situ cardiac performance during 2 h of acute anoxia in juvenile turtles previously exposed to normoxia …

The Hox Protein Conundrum: The “Specifics” Of Dna Binding For Hox Proteins And Their Partners, Bony De Kumar, Diane C. Darland

Biology Faculty Publications

Homeotic genes (Hox genes) are homeodomain-transcription factors involved in conferring segmental identity along the anterior-posterior body axis. Molecular characterization of HOX protein function raises some interesting questions regarding the source of the binding specificity of the HOX proteins. How do HOX proteins regulate common and unique target specificity across space and time? This review attempts to summarize and interpret findings in this area, largely focused on results from in vitro and in vivo studies in Drosophila and mouse systems. Recent studies related to HOX protein binding specificity compel us to reconsider some of our current models for transcription factor-DNA …

September 2, 2021: Agenda, University Of North Dakota

University Senate Meeting Minutes

Agenda for the September 2, 2021, meeting of the University Senate. 21 pages

Summer Commencement: August 6, 2021, University Of North Dakota

UND Commencement Programs

UND Summer Commencement program from August 6, 2021.

Participant Reference In Colombian Sign Language Narrative, Martha Lois Gateley

Theses and Dissertations

Much of the research on discourse in sign languages thus far has been carried out on American Sign Language. With this thesis, I add to the current research by comparing what is known about participant reference in American Sign Language with Colombian Sign Language.

This thesis analyzes six separate stories totaling 72 minutes, signed by 5 different native signers of Colombian Sign Language. ELAN (a computer software for annotation) was used to mark all of the referring terms in the subject position and categorize the terms by type (nominal reference, pronominal reference, zero-anaphor, and classifier) and by function (introduction, reintroduction …

Managing For Radical Ecosystem Change: Applying The Resist-Accept-Direct (Rad) Framework, Abigail J. Lynch, Laura M. Thompson, Erik A. Beever, David N. Cole, Augustin C. Engman, Cat Hawkins Hoffman, Stephen T. Jackson, Trevor J. Krabbenhoft, David J. Lawrence, Douglas Limpinsel, Robert T. Magill, Tracy A. Melvin, John M. Morton, Robert Newman, Jay O. Peterson, Mark T. Porath, Frank J. Rahel, Gregor W. Schuurman, Suresh A. Sethi, Jennifer L. Wilkening

Biology Faculty Publications

Ecosystem transformation involves the emergence of persistent ecological or social–ecological systems that diverge, dramatically and irreversibly, from prior ecosystem structure and function. Such transformations are occurring at increasing rates across the planet in response to changes in climate, land use, and other factors. Consequently, a dynamic view of ecosystem processes that accommodates rapid, irreversible change will be critical for effectively conserving fish, wildlife, and other natural resources, and maintaining ecosystem services. However, managing ecosystems toward states with novel structure and function is an inherently unpredictable and difficult task. Managers navigating ecosystem transformation can benefit from considering broader objectives, beyond a …

Nanozymes—Hitting The Biosensing “Target”, Yingfen Wu, Diane Darland, Julia Zhao

Biology Faculty Publications

Nanozymes are a class of artificial enzymes that have dimensions in the nanometer range and can be composed of simple metal and metal oxide nanoparticles, metal nanoclusters, dots (both quantum and carbon), nanotubes, nanowires, or multiple metal-organic frameworks (MOFs). They exhibit excellent catalytic activities with low cost, high operational robustness, and a stable shelf-life. More importantly, they are amenable to modifications that can change their surface structures and increase the range of their applications. There are three main classes of nanozymes including the peroxidase-like, the oxidase-like, and the antioxidant nanozymes. Each of these classes catalyzes a specific group of reactions. …

Open Pedagogy: A Systematic Review Of Empirical Findings, Virginia Clinton-Lisell

Education, Health & Behavior Studies Faculty Publications

Open licensing used in open educational resources allows for teaching and learning practices that are not possible with traditional copyright. There is a growing body of empirical research on open pedagogy. However, definitions and instantiations of open pedagogy vary in the literature. The purpose of this review was to systematically search and synthesize empirical findings on open pedagogy. In this, the definitions of open pedagogy across empirical reports were examined. Generally, open pedagogy was defined in the context of open licensing affordances; however, there were exceptions particularly when examining faculty experiences with open pedagogy. Synthesized findings may be used by …

Stress And Coping During Simulated Evas And Habitat Living, Gloria R. Leon, Travis Nelson, Pablo De Leon

Space Studies Faculty Publications

Planning for long duration exploration missions (LDEM) involves both the effectiveness of the extravehicular operations, in particular as it is related to the functioning and comfort of the space suits, and how the crew functions together in accomplishing the objectives of the mission. The University of North Dakota Department of Space Studies has developed a multi-modular Inflatable Lunar/Mars Analog Habitat (ILMAH) and is testing iterations of their NDX-2AT space suit. Five 12-14 day missions, each consisting of 3-4 individuals (Total 13; 11 men, two women) were carried out. Team members independently completed a Daily Rating Form (DRF) each day of …

Interactive Features Of E-Texts’ Effects On Learning: A Systematic Review And Meta-Analysis, Virginia Clinton-Lisell, Ben Seipel, Staci Gilpin, Christine Litzinger

Education, Health & Behavior Studies Faculty Publications

E-texts afford interactive features that are not feasible with paper texts. Several studies have been conducted examining interactive features of E-texts, but it is uncertain what the overall effect is or what features may be most useful. The purpose of this study is to systematically review and meta-analysis of the findings comparing reading performance and/or reading times between E-texts with interactive features and control texts (paper or static E-texts). The systematic search of the literature identified 26 independent studies on reading performance. Based on the meta-analysis, interactive features benefited reading performance (g = .66, p < .001). Individual studies with positive effects involved multiple interactive features; however, potential contributions of three types of features (questions with feedback, digital glossaries, and collaborative tools) are discussed. Future directions for examining interactive features experimentally to better understand what features are most helpful for whom are described.

The Interaction Of Open Educational Resources (Oer) Use And Course Difficulty On Student Course Grades In A Community College, Lane Fischer, John Hilton Iii, Virginia Clinton-Lisell, Yao Xiong, David Wiley, Linda Williams

Education, Health & Behavior Studies Faculty Publications

Students report that not being able to afford course materials has adverse academic consequences. It is possible that this would be more problematic in relatively more difficult courses. Open Educational Resources (OER) are teaching and learning materials that are openly licensed and often available at low or no cost to students. This study examined the interaction between OER use through a campus zero textbook cost (ZTC) initiative and course difficulty on student course grades from 35 different courses at a community college while controlling for student gender, previous grade point average, and Pell grant eligibility status. Although the main effect …

Spring Commencement: May 15, 2021, University Of North Dakota

UND Commencement Programs

UND Spring Commencement program from May 15, 2021.