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Articles 2311 - 2340 of 14258
Full-Text Articles in Entire DC Network
Managing Anxiety With Pharmacogenomic Testing, Ashley Pommer
Managing Anxiety With Pharmacogenomic Testing, Ashley Pommer
Physician Assistant Scholarly Project Papers
Anxiety affects approximately three to seven percent of the United States population, and nearly 50% of the diagnosed patients fail to respond to first-line treatment regimens (Boland, Duffy, & Meyer 2018). Traditional first-line treatments include medication therapy, cognitive behavioral therapy (CBT), or the combination of both. With such a high initial failure rate, recent studies indicate promising results in managing anxiety with pharmacogenomic testing. Pharmacogenomic testing is allowing providers to prescribe medication based on individual genetic makeup, focusing on how each patient metabolizes certain medications. The purpose of this literature review was to determine if first-line methods or pharmacogenomic testing …
Expedited Partner Therapy Using Oral Cefixime And Oral Azithromycin For Gonorrheal And Chlamydial Infections Among Adult Outpatients In The United States, Nicholas Coburn-Pierce
Expedited Partner Therapy Using Oral Cefixime And Oral Azithromycin For Gonorrheal And Chlamydial Infections Among Adult Outpatients In The United States, Nicholas Coburn-Pierce
Physician Assistant Scholarly Project Papers
Sexually transmitted infections (STI) such as Neisseria Gonorrhoeae and Chlamydia Trachomatis pose a challenge to the healthcare system worldwide. Treating sexual partners is as crucial to controlling the spread of these infections as treating index patients. However, because of problems associated with stigma, reaching affected populations, and ensuring follow-up, unique solutions are require to ensure partners receive treatment. One solution is Expedited Partner Therapy (EPT). EPT refers to treating patients, and providing necessary medication for both patient and partner. Current recommendations are for oral doses one gram of azithromycin and 400 milligrams of cefixime. This literature review looked at thirteen …
Can Early Intervention With Group Therapy Or Individual Therapy Improve The Family Dynamic In Ptsd Patients?, Killian Norton
Can Early Intervention With Group Therapy Or Individual Therapy Improve The Family Dynamic In Ptsd Patients?, Killian Norton
Physician Assistant Scholarly Project Papers
Post-Traumatic Stress Disorder (PTSD) is a mental health disorder that affects an individual directly, while also affecting their family members around them. While PTSD is not directly correlated to the development of Secondary Stress Disorder (STS), PTSD has been shown to lead to increased rates of divorce and mood disorders in children whose parents are diagnosed with PTSD. Children who have grown up with divorced parents, or parents with PTSD, have been shown to have an increased chances of developing mood disorders and risky lifestyle behaviors. The combination of having a parent with PTSD who are also divorced, would likely …
Is A Varicocelectomy Beneficial In The Era Of Assisted Reproductive Technologies?, Chukwuka Oscar Nnoli
Is A Varicocelectomy Beneficial In The Era Of Assisted Reproductive Technologies?, Chukwuka Oscar Nnoli
Physician Assistant Scholarly Project Papers
Clinical varicoceles are the most frequent physical finding associated with infertile men and impaired semen parameters. There is evidence that suggests varicocele repair improves semen parameter and increases the chances of natural pregnancy. Today, varicocele repair is often combined with assisted reproductive techniques (ART) such as intrauterine insemination (IUI), in Vitro fertilization (IVF) or intracytoplasmic sperm injection (ICSI). In this literature review, data examining whether varicocelectomy before ART leads to improved pregnancy outcomes is reviewed. Current data suggest that there is a significant clinical benefit when correcting a varicocele in oligospermic men before IVF/ICSI. Similarly, men with non-obstructive azoospermia also …
Comparing Rates Of Macrosomia And Neonatal Hypoglycemia Of Differing Treatment Modalities Of Gestational Diabetes Mellitus, Ashleigh Milbrath
Comparing Rates Of Macrosomia And Neonatal Hypoglycemia Of Differing Treatment Modalities Of Gestational Diabetes Mellitus, Ashleigh Milbrath
Physician Assistant Scholarly Project Papers
Gestational diabetes mellitus (GDM) is a known potential complication that can occur during pregnancy. Unmanaged GDM can result in maternal hyperglycemia, which can cause increased neonatal complications, two of which are macrosomia and neonatal hypoglycemia. To prevent maternal hyperglycemia, treatment of GDM typically begins with dietary changes, home glucose monitoring, increased exercise patterns and other lifestyle modifications. However, if maternal hyperglycemia persists after two weeks of maternal lifestyle modifications, there are not current best practice guidelines established for the treatment of GDM. Historically, subcutaneous multiple daily dosed insulin (MDI) has been the gold standard for treatment after lifestyle modification. However, …
Glucagon-Like Peptide-1s Compared To Sulfonylureas In The Treatment Of Adults Diagnosed With Type Ii Diabetes Mellintus In Primary Care, Tracy Kirchner
Glucagon-Like Peptide-1s Compared To Sulfonylureas In The Treatment Of Adults Diagnosed With Type Ii Diabetes Mellintus In Primary Care, Tracy Kirchner
Physician Assistant Scholarly Project Papers
Type II diabetes mellitus (T2DM) is a prevalent disease in our country. Bullard et al. (2018) report approximately 21 million adults have T2DM in the United States. “The total estimated cost of diagnosed diabetes in 2017 is $327 billion, including $237 billion in direct medical costs and $90 billion in reduced productivity” (Yang et al., 2018). Treatment of T2DM is individualized to each patient based on their co-morbidities, fiscal responsibility, and route of administration options. Sulfonylureas and Glucagon-like Peptide-1s (GLP-1) are two classes of antidiabetic drugs that are available for use as second line treatment options after metformin. This review …
Pharmacotherapy For Impulsivity-Hyperactivity Behaviors In Autism Spectrum Disorder, Jenna Katnis
Pharmacotherapy For Impulsivity-Hyperactivity Behaviors In Autism Spectrum Disorder, Jenna Katnis
Physician Assistant Scholarly Project Papers
The incidence of Autism Spectrum Disorder (ASD) in 8-year old children is 1 in 59. This increased from approximately 1 in 150 reported in 2000-2002 (Baio et al., 2014). Autism includes deficits in social emotional reciprocity, non-verbal communication for social interactions, developing and maintaining relationships and in some cases, hyperactivity response to sensory input. Hyperactivity is a shared behavior with ASD and Attention Deficit Hyperactivity Disorder (ADHD). Medications such as Methylphenidate (MPH) and α 2-a adrenergic receptor agonists are used to modify hyperactivity behavior in ADHD and thus have been used as management in ASD. A review of literature was …
Outcomes In Treatment Of Major Depressive Disorder: Pharmacogenomic Testing Vs. Treatment As Usual, Zachary Horoshak
Outcomes In Treatment Of Major Depressive Disorder: Pharmacogenomic Testing Vs. Treatment As Usual, Zachary Horoshak
Physician Assistant Scholarly Project Papers
The goal of this systematic literature review is to evaluate the efficacy and cost effectiveness of pharmacogenomic testing (PGx) versus treatment as usual (TAU) in the treatment of major depressive disorder (MDD). According to Huang & Lin (2015), MDD is characterized by multiple signs and symptoms consisting of mood, vegetative, cognitive, and even psychotic behaviors that may cause substantial impairment in the functioning and quality of life in an affected individual. This literature review consisted of articles found in PubMed, Cochrane, and PsychINFO which were extensively reviewed. Articles prior to 2008 were excluded due to the ever-changing landscape of PGx …
Comparison Of Rivaroxaban And Warfarin In The Prevention Of Recurrent Venous Thromboembolism, Philip Joel Heiden
Comparison Of Rivaroxaban And Warfarin In The Prevention Of Recurrent Venous Thromboembolism, Philip Joel Heiden
Physician Assistant Scholarly Project Papers
The purpose of this systematic literature review is to determine the efficacy and safety of rivaroxaban (Xarelto) compared to warfarin (Coumadin), for the long term prophylaxis of recurrent venous thromboembolism (VTE). Rivaroxaban was chosen as the primary representative of factor Xa inhibitors because of its simplistic once a day dosing regimen. The PubMed database was extensively searched, using a variety of key terms, from September 10 to November 30, 2018. Works chosen include propensity-matched cohorts, retrospective studies, systematic reviews, and meta-analyses. All of which were published within the last 10 years; sources dated prior to 10 years were excluded. Studies …
Reducing The Health Care Burden Caused By Undocumented Immigrants, Juan Carlos Garcia
Reducing The Health Care Burden Caused By Undocumented Immigrants, Juan Carlos Garcia
Physician Assistant Scholarly Project Papers
Uncompensated health care and Emergency Department (ED) overcrowding are a national crisis in the United States, and uninsured patients are a major contributor. Undocumented Immigrants (UIs) are a large component of the uninsured patient population. The purpose of this study is to evaluate for efficacy and taxpayer value two large-scale potential solutions: Federally Qualified Health Centers (FQHCs), and expanded Medicaid. A brief analysis of smaller-scale solutions is also included. This study utilized a variety of key terms in electronic search databases such as CINAHL Complete, PubMed, and Google Scholar, and only articles published between 2014 and 2018 by peer-reviewed journals …
The Impact Of Shift Work On Health And Wellbeing, Stephanie Gagelin
The Impact Of Shift Work On Health And Wellbeing, Stephanie Gagelin
Physician Assistant Scholarly Project Papers
Many of today’s industries require workers to perform shift work (typically during 1600-0700). If workers are awake during this time period, circadian misalignment occurs. This scholarly project uses research studies and meta-analyses to provide information about increased health risks associated with circadian misalignment, focusing particularly on the categories of glucose metabolism, cardiovascular system, carcinogenesis, and mental health and acuity. Shift work has been found to increase BMI and waist circumference of employees, as well as increase blood glucose levels to “prediabetic” levels in previously euglycemic individuals. Shift work has been proven to increase high-sensitivity C-reactive protein (hs-CRP), an acute phase …
Exercise Compared To Ssris In The Treatment Of Major Depressive Disorder, Tiffany Fletschock
Exercise Compared To Ssris In The Treatment Of Major Depressive Disorder, Tiffany Fletschock
Physician Assistant Scholarly Project Papers
Major Depressive Disorder (MDD) is a common disease seen every day by primary care providers across the United States. According to the Centers for Disease Control and Prevention (CDC, 2018), eight percent of all adults over the age of 20 suffer from depression, and a study by the American Psychological Association found depressive disorders to cost roughly $71 billion annually. Today, psychotherapy is the recommended first-line therapy for treating MDD, but pharmacotherapy is more commonly used. Alternative forms of therapy are also being researched in order to avoid the use of medication while adequately treating the symptoms of MDD. For …
Embolus Prevention: Anticoagulant Therapy In Comparison To Watchman's Procedure In Patients With Atrial Fibrillation, Erik Fladmo
Embolus Prevention: Anticoagulant Therapy In Comparison To Watchman's Procedure In Patients With Atrial Fibrillation, Erik Fladmo
Physician Assistant Scholarly Project Papers
Atrial fibrillation is a common cardiac disease that occurs as individuals age. One of the risk factors of atrial fibrillation is blood clot formation or embolus in the left atrium. Current treatment methods to prevent clot formation include a variety of anticoagulants, and left atrial appendage closure devices, specifically the relatively new Watchman’s device, the only FDA approved left atrial appendage closure device. This literature review researched articles comparing the differences in both long-term anticoagulation therapy and Watchman’s device for blood clot prevention. Study results confirm the rising efficacy and cost effectiveness of Watchman’s device versus long term anticoagulant therapy …
The Impact Of Medical Marijuana On The Opioid Crisis, Carl David Estep
The Impact Of Medical Marijuana On The Opioid Crisis, Carl David Estep
Physician Assistant Scholarly Project Papers
In light of the current opioid crisis, research is needed to identify alternative treatments for acute and chronic pain. With medical marijuana being made available by rapidly changing state laws, it is prudent to identify what role it may play in pain control. This comprehensive literature review was conducted to determine what is known as to the effectiveness of medical marijuana, cannabis, or cannabinoids for treating acute and chronic pain as compared to prescription opiates. An additional comparison was also made between the addictive properties and adverse effects of medical marijuana and prescription opiates. The final parameter evaluated was the …
Fertility Options For Women With Endometriosis: In Vitro Fertilization Versus Surgical Excision Or Ablation, Jenny L. Brown
Fertility Options For Women With Endometriosis: In Vitro Fertilization Versus Surgical Excision Or Ablation, Jenny L. Brown
Physician Assistant Scholarly Project Papers
Endometriosis negatively affects the fertility of many women of reproductive age worldwide. Some women with endometriosis are able to conceive without reproductive assistance, while others require medical intervention. In vitro fertilization and surgical management are available and widely used in the treatment of endometriosis associated infertility. In vitro fertilization has been found to be effective in women with stages I-IV endometriosis, with varying degrees of success at each stage. These varying results may be due to oocyte quality and availability as well as endometriosis location. Surgical excision and/or surgical ablation of endometriosis/endometriomas may also improve chance of successful pregnancy but …
Treatment Options For Post Treatment Lyme Disease Syndrome, Barbara Bowman
Treatment Options For Post Treatment Lyme Disease Syndrome, Barbara Bowman
Physician Assistant Scholarly Project Papers
With the high incidence of Lyme disease in the endemic areas of North America, it is important to appropriately diagnosis and treat this condition to prevent post treatment Lyme disease syndrome (PTLDS). Background information regarding Lyme disease is given. The purpose of this paper is to discuss the treatment options available for those patients that fit the case definition of PTLDS. A literature review was conducted using several different electronic databases finding peer reviewed research articles pertaining to the treatment options available for PTLDS. Extended antibiotic use is shown to be not beneficial in most cases. Alternative treatment options listed …
Aspirin Use Following Preeclampsia To Prevent Future Cardiovascular Outcomes, Kristi Bohlig
Aspirin Use Following Preeclampsia To Prevent Future Cardiovascular Outcomes, Kristi Bohlig
Physician Assistant Scholarly Project Papers
Abstract Introduction: Preeclampsia during pregnancy warrants therapy with low dose aspirin. The purpose of this review is to investigate whether these women are at increased future risk for cardiovascular morbidity and mortality, and if aspirin therapy should be continued following the puerperium to prevent future cardiovascular events. Research Questions: Do women who had preeclampsia during pregnancy, have increased future cardiovascular morbidity and mortality? Does continued aspirin use in postpartum women, who had preeclampsia during pregnancy, decrease future cardiovascular morbidity and mortality outcomes? Research Methods: Literature review was conducted utilizing CINAHL, Dynamed plus and PubMed databases. Discussion: It is found that …
Pelvic Examinations For Ovarian Cancer Screening In Asymptomatic Adult Women, Riann Sue Collar
Pelvic Examinations For Ovarian Cancer Screening In Asymptomatic Adult Women, Riann Sue Collar
Physician Assistant Scholarly Project Papers
There is discrepancy amongst organizations and the medical community whether bimanual pelvic examinations should be performed in asymptomatic women for routine screening. The purpose of this literature review was to determine whether bimanual pelvic examinations are beneficial for screening for ovarian cancer in comparison to no screening. In addition, research was conducted to see if healthcare providers’ professional beliefs align with the evidence and national recommendations, to determine women’s thoughts and beliefs regarding pelvic examinations, and if bimanual pelvic exams are not a valid screening tool for ovarian cancer, what are other screening methods available. Throughout reviewing peer reviewed articles …
Platelets To The Rescue? A Literature Review Of The Safety And Efficacy Of Platelet-Rich Plasma For Symptomatic Knee Osteoarthritis, Timothy Simonich
Platelets To The Rescue? A Literature Review Of The Safety And Efficacy Of Platelet-Rich Plasma For Symptomatic Knee Osteoarthritis, Timothy Simonich
Physician Assistant Scholarly Project Papers
Osteoarthritis (OA) of the knee is one of the most common joint disorders in the United States with rising prevalence due to obesity and an aging population. Regarding non-surgical approaches to management, there has been growing interest in the use of intra-articular injections (IAI) of Platelet Rich Plasma (PRP). However, there has been a lack of strong evidence to support its use in clinical practice guidelines. In this literature review, two search methods were utilized in an effort to, first, inform clinicians about PRP and, second, to shed light on recent clinical control trials regarding the safety and efficacy of …
Benefits Of 3d Breat Tinisynthesis Combined With 2d Digital Mammography In Screening Women For Breast Cancer, Danielle M. Swanson
Benefits Of 3d Breat Tinisynthesis Combined With 2d Digital Mammography In Screening Women For Breast Cancer, Danielle M. Swanson
Physician Assistant Scholarly Project Papers
Breast cancer screening imaging options have progressed greatly over the years in sensitivity, specificity, and image quality. According to DynaMed Plus, in 2012 there were 522,000 deaths by breast cancer and 1,677,000 total cases of breast cancer documented (Dynamed, 2018). For years, traditional screening for breast cancer involved 2D digital mammography which obtains two views of each breast. With advances in technology, the use of 3D breast tomosynthesis has become an advantageous addition to routine breast cancer screening protocols at many health care facilities. My literature review of articles was found in PubMed, DynaMed Plus, Cochrane Library, and Clinical Key …
Benefits Of Hpv Vaccination In Adolescent Males, Budd Theriot
Benefits Of Hpv Vaccination In Adolescent Males, Budd Theriot
Physician Assistant Scholarly Project Papers
Human papilloma virus (HPV) is a collection of between 120-150 viral strains that effect epithelial and mucosal tissue. Infections due to HPV are extremely common and some of the more high-risk strains can lead to severe consequences later in life. HPV is the most common sexually transmitted infection in the United States, affecting approximately 75-80% of young adults at some point in their lives, and it is also known to be directly related to several forms of cancer including cervical, vaginal, penile, anal, oral, and oropharyngeal cancer. Vaccination against several high-risk strains of HPV first became available in the U.S. …
Comparison Of Pharmacologic Treatments For Postmenopausal Osteoporosis, Kaitlyn Wirtz
Comparison Of Pharmacologic Treatments For Postmenopausal Osteoporosis, Kaitlyn Wirtz
Physician Assistant Scholarly Project Papers
Osteoporosis is defined as a “generalized skeletal disorder characterized by compromised bone strength and deterioration of bone quality, often leading to fragility fracture” (DynaMed Plus, 2018). The prevalence of osteoporosis in the United States in adults aged greater than or equal to 50 years of age is “more than 10 million people overall and 33 million have low bone mineral density at the hip” (DynaMed Plus, 2018). Of these affected, one in two women will experience an osteoporotic fracture in their lifetime (International Osteoporosis Foundation, 2017). To combat postmenopausal osteoporosis, two treatment options include bisphosphonates and the anti-receptor activator of …
Color And Pigment Polymorphisms Of Northern Leopard Frogs On A Prairie Landscape, Kyle D. Gustafson, Bartholomew L. Bly, Robert A. Newman
Color And Pigment Polymorphisms Of Northern Leopard Frogs On A Prairie Landscape, Kyle D. Gustafson, Bartholomew L. Bly, Robert A. Newman
Biology Faculty Publications
Variation allows populations to adapt to changing conditions. As human activities continue to alter environments and evolutionary processes, it becomes increasingly important to conserve standing genetic variation. Despite technical advances in population genetics, it is still useful to have inexpensive methods of detecting and monitoring genetic variation, particularly in traits that potentially influence fitness. In the Northern Leopard Frog, Lithobates pipiens (= Rana pipiens), genetically determined color (green [dominant: G] or brown [recessive: g]) and two pigment pattern polymorphisms (Burnsi/spotless [B] or spotted [b]; Kandiyohi/mottled [K] or non-mottled[k]) are hypothesized to have adaptive benefits. We assessed spatiotemporal patterns of these …
April 30, 2019, The Dakota Student
Benchmarking Image Processing Algorithms For Unmanned Aerial System-Assisted Crack Detection In Concrete Structures, Sattar Dorafshan, Robert J. Thomas, Marc Maguire
Benchmarking Image Processing Algorithms For Unmanned Aerial System-Assisted Crack Detection In Concrete Structures, Sattar Dorafshan, Robert J. Thomas, Marc Maguire
Civil Engineering Faculty Publications
This paper summarizes the results of traditional image processing algorithms for detection of defects in concrete using images taken by Unmanned Aerial Systems (UASs). Such algorithms are useful for improving the accuracy of crack detection during autonomous inspection of bridges and other structures, and they have yet to be compared and evaluated on a dataset of concrete images taken by UAS. The authors created a generic image processing algorithm for crack detection, which included the major steps of filter design, edge detection, image enhancement, and segmentation, designed to uniformly compare different edge detectors. Edge detection was carried out by six …
Problem Based Learning With Teamstepps®, Dana Clairmont
Problem Based Learning With Teamstepps®, Dana Clairmont
Nursing Capstones
No abstract provided.
Support And Mentorship Of Diverse And Disadvantaged Nursing Students, Elle E. Hoselton
Support And Mentorship Of Diverse And Disadvantaged Nursing Students, Elle E. Hoselton
Nursing Capstones
No abstract provided.
Evaluating The Correlation Of Diabetes And Gallbladder Disease, Robbi A. Yellow
Evaluating The Correlation Of Diabetes And Gallbladder Disease, Robbi A. Yellow
Nursing Capstones
No abstract provided.
Volume 56, Number 36: April 24, 2019, University Of North Dakota
Volume 56, Number 36: April 24, 2019, University Of North Dakota
University Letter Archive
No abstract provided.
May 2, 2019: Agenda, University Of North Dakota
May 2, 2019: Agenda, University Of North Dakota
University Senate Meeting Minutes
Agenda for the May 2, 2019, meeting of the University Senate. 175 pages