Digital Commons Network^™

Cell Membrane Facilitators: Nucleotide-Amine Linkages., Michael Yiu-Ming Chan

Theses and Dissertations

In order to facilitate the transport of a nucleotide across an artificial lipid bilayer, different amines were conjugated to the phosphate group of adenosine 5$\sp\prime$-phosphate. The effect of the amine conjugation was to enhance the lipophilicity of the consequent adenosine 5$\sp\prime$-phosphoramidate derivative.The synthesis of various nucleoside 5$\sp\prime$-phosphoramidate analogs have been investigated, using different methodologies. Adenosine 5$\sp\prime$-phosphoromorpholidate, 5$\sp\prime$-phosphor(adamantyl)amidate, (n-decyl)amidate, (n-stearyl)amidate, and (1,4,7,10,13-pentaoxo-16-azacyclooctadecyl)amidate were synthesized by adopting Moffatt and Khorana's procedures. Among these phosphoramidate analogs, the adamantyl, aza-18-crown-6, and stearyl derivates have never been reported before. These amine-nucleotides were prepared by refluxing a reaction mixture of the corresponding amine (4 fold excess), …

Studies On The Toxicity Of Ninhydrin For Bacteria, Shanti Rawat

Theses and Dissertations

No abstract provided.

Novalis' And Tieck's Use Of Mountain, Stone, Ore, And Gem Imagery As Poetic Expression, Bennett P. Olson

Theses and Dissertations

No abstract provided.

Systems Analysis Of The Carotid Sinus Viscoelastic Properties And Their Impact On Multifiber Baroreceptor Nerve Activity, Christopher L. Taylor

Theses and Dissertations

No abstract provided.

Dancing About Architecture, J Paul Johnson

Theses and Dissertations

No abstract provided.

Hormones And Behavior In Chinook Salmon (Onchorhyncus Tschawytscha) And Steelhead Trout (Salmo Gairdneri) During Smoltification, Thomas P. Mccreery

Theses and Dissertations

No abstract provided.

Teaching As Landmark: Metaphors And Education, Delese Wear

Teaching and Learning: The Journal of Natural Inquiry & Reflective Practice

No abstract provided.

Madeline Hunter's Teaching Machine, Richard A. Ghibboney

Teaching and Learning: The Journal of Natural Inquiry & Reflective Practice

No abstract provided.

An Interdisciplinary Curriculum Model For Outdoor Education, Larry L. Lang

Theses and Dissertations

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The primary purpose of this study was to develop an interdisciplinary curriculum model which would improve the conceptualization, of outdoor education by providing a theoretical framework for curriculum development, evaluation, and further research.

In order to create the proposed model, it was necessary to address several related issues. The first phase of the study involved an investigation of current perspectives on outdoor education. Key characteristics and guiding principles were determined to provide a clarification of the substantive structure of this field of study. An analysis and synthesis of the contributions of John Dewey,.L.. B. Sharp, Julian Smith, and other …

Marking Papers And Marking Time: How Women And Men Perceive As Teachers, Janet L. Miller

Teaching and Learning: The Journal of Natural Inquiry & Reflective Practice

No abstract provided.

Reflections On Childhood And Change, Patricia F. Carini

Teaching and Learning: The Journal of Natural Inquiry & Reflective Practice

No abstract provided.

A Comparison Of Hypnosis And Behavioral Treatments For Obesity With One Year Follow-Up, Judith A. Haynes

Theses and Dissertations

This study was designed to examine the effects of hypnotherapy on both short-term and long-term weight loss when combined with a group behavioral weight loss program. At the beginning of the study, 38 obese female subjects (20% over normal body weight), ranging in age from 21 to 64, were randomly assigned to one of two treatment groups, one utilizing behavior therapy only and the other utilizing behavior therapy plus hypnotherapy.

The groups mot weekly for 1-1/2 hours for 8 consecutive weeks, with follow-up sessions, at 3, 6, 9, and 12 months. Twenty-eight women completed the study. The first hour in …

Preschool Behavioral Precursors Of The Delinquency Of Juvenile Offenders: A Retrospective Study, Kay A. Halverson

Theses and Dissertations

Early behaviors of juvenile offenders and nonoffenders were studied to assess differences between the two groups. Experimental subjects were 50 youth residing in three northeastern counties of North Dakota who had committed two or more offenses. Control subjects were 50 non-offenders matched for birthdate, sex, and school. Data were collected retrospectively from both groups on Form 1 of the Louisville Behavior Checklist (LBC)» an inventory designed to detect psychopathological behaviors among preschool children. The responses were analyzed in terms of hypotheses that were designed to address (a) which scales of the LBC would show a significant difference between the offender …

The Effects Of Caffeine In Free Recall, Mary Ellen Arnold

Theses and Dissertations

Caffeine, a central nervous system stimulant, is said to produce an elevation in level of arousal. Humphreys and Revelle (1984) have proposed a model to account for changes in information processing efficiency resulting from differences in personality, situational moderators such as caffeine, and type of information processing task. According to the model, a high level of state arousal will result in poor performance on shortterm memory tasks, while improved performance will occur at a low level of arousal. In this experiment, subjects' trait level of arousal, as measured by the impulsivity subscale of the Eysenck Personality Inventory, was manipulated by …

A Survey Of Attitudes About Science Fairs In White Shield School, Donald R. Yellowbird

Theses and Dissertations

No abstract provided.

Computer Aided Drafting, Lou Shi-Jer

Theses and Dissertations

No abstract provided.

The Effects Of Text Genre And Importance Level On Grade And Reading Ability Differences In Prose Memory, Barbara Bentz

Undergraduate Theses and Senior Projects

No abstract provided.

The Right, The New Right, And The New Religious Right; Educational Positions, Postures, And Preachments, Katherine Marie Dahl

Theses and Dissertations

No abstract provided.

Guided Fantasy: A Tool For Therapy, Marcia L. Healy

Theses and Dissertations

The purpose of this study was to investigate the feasibility of using instructed guided fantasy to decrease anxiety in a child with juvenile rheumatoid arthritis. It was intended that the child would use guided fantasy to develop an internal coping mechanism for reducing anxiety during a weekly gold shot injection, which was identified as anxiety-producing. An embedded, single-case design was selected for this case study. Qualities of guided fantasy were globally examined. Other aspects of the subject's performance, which were examined included musculoskeletal abilities and limitations, cognitive abilities, ability of the subject to relax via specific relaxation exercises, the subject's …

An Analysis Of The Comic Elements In A Production Of Joe Orton's Entertaining Mr. Sloane, Mary Beth J. Barder

Theses and Dissertations

This analysis addresses the classification of a production of Joe Orton's play Entertaining Mr. Sloane as a comedy. Its intent is to question the classification by considering several factors.

The thesis begins with an introduction, contained in Chapter I. Chapter II applies several concepts of comic theory as conceived by Susanne K. Langer, to the play. The third chapter offers the background of the playwright and the play's past reception by theatre critics. Chapter IV deals with the directing of a production of Entertaining Mr. Sloane, presented at the University of North Dakota in November, 1985. It includes a pre-production …

The Effect Of Histamine On Lanthanum (La3+) Binding In The Isolated Rabbit Heart In The Presence Of Verapamil, Scott A. Barman

Theses and Dissertations

Two of the major effects of histamine in the rabbit heart are the enhancement of contractility and microvascular permeability. In cardiac muscle it has been documented that calcium (Ca ) bound to the sarcolem- mal-glycocalyx complex is essential for the regulation of the contractile response. In addition, it has been postulated that histamine's regulation of microvascular permeability may occur via an endothelial contractile response causing the formation of submicroscopic gaps between endothelial cells. It was postulated that these effects of histamine may in- O . volve an alteration of Ca r binding to the plasma membranes of these tissues. In …

Art As Therapy For The Emotionally And Behaviorally Disturbed Child In School, Karen Kresl Zabel

Theses and Dissertations

No abstract provided.

Learning Through Play In Severly And Multiply Handicapped Preschool Children, Denise D. Martell

Theses and Dissertations

No abstract provided.

The Invention Of Oz, Janet Faye Daley Lysengen

Theses and Dissertations

Since L. Frank Baum published his first Oz book in 1900, Oz has become an integral part of American society; yet, only recently have his books begun to receive critical attention. Critics seem most interested in dealing with them in terms of sociology, popular culture, and psychology, but a few have recognized Baum's contributions to the birth of science fiction, to the depiction of a female hero in Dorothy, and to Baum's imaginative and perceptive examination of what separates humans from machines. This thesis will analyze the literary dimension of the Oz series. The goal will be to perceive the …

Duration Estimation : A Comparison Among Three Methods Of Absolute Judgment, Rosanne B. Mcbride

Undergraduate Theses and Senior Projects

No abstract provided.

The Effects Of A Cyclic Analog Of Alpha-Msh/Acth 4-10 On Reactivation Of Memory After Hypothermia Induced Amnesia, Craig R. Sprenger

Undergraduate Theses and Senior Projects

No abstract provided.

April 1986, University Of North Dakota Alumni Association

ALL: UND Alumni Review Master List

March 1986 issue of "The University of North Dakota Alumni Review." 11 pages

Volume 68, Number 8

Character Evidence - Footprints In The Civil Snow, Michael Dietz

North Dakota Law Review

No abstract provided.

Serotonergic Mediation In The Activity Of Anticonvulsant Compounds (Neurotransmitter, Diazepam, Phenytoin)., Larry Marvin Leadbetter

Theses and Dissertations

The role of the central nervous system neurotransmitter serotonin was evaluated on the anticonvulsant activity of various compounds. Serotonin (5-hydroxytryptamine) is known to have an inhibitory role in central nervous system activity. A facilitation of the anticonvulsant activity of benzodiazepines has previously been attributed to increased serotonin activity.Male white mice of the ICR strain were administered varying doses of phenytoin, 5-ethyl, 5-methylhydantoin (EMH) and JAW-669, then challenged with maximal electroshock. The occurrence of seizures was used to evaluate the degree of protection provided by a given dose of anticonvulsant.The role of serotonin on the anticonvulsant activity of these compounds was …

Effects Of Zinc Deficiency On Sertoli Cell Number And Ultrastructure: An In Vivo And In Vitro Study., Gro Thorne-Tjomsland

Theses and Dissertations

Hypogonadism in the male is a well known clinical symptom of zinc deficiency. The testicular lesions have been primarily attributed to the effects of decreased zinc on germ cells. This study assessed possible effects of zinc deficiency on Sertoli cell number and ultrastructure.Long-Evans dams and their newborn litters were placed on zinc deficient (ZD), pair-fed or ad libitum fed (AL) diets. All dams received a 20% egg white based diet containing less than one ppm zinc. ZD dams received distilled, deionized water (<1 ppm ZN), while PF and AL dams received the above water fortified with 25 ppm zinc. Male pups were sacrificed day 10 and their testes were processed for light (LM) and transmission electron microscopy (TEM).LM cell counts were performed on one (mu)m sections. Average number of germ cells on the basement membrane (BM) (=GC2) per tubular cross-section was reducted by two-thirds in ZD and PF compared to AL animals (p < 0.0001). Average number of germ cells not on the BM (=GC1) and average number of Sertoli cells per tubular cross-section were not statistically different in the three diet groups.Volume fractions of TEM subcompartments/total cytoplasm were determined by morphometric methods. The lysosome-like fraction was doubled in ZD and PF compared to AL animals (p < 0.05). Endoplasmic reticulum, Golgi and mitochondrial fractions were not statistically different in the three diet groups.Five day old Sertoli cell cultures derived from ZD, PF and AL pups were volumetrically analyzed as in vivo. The endoplasmic reticulum fraction was approximately 100% lower in ZD- than in AL-derived cultures (p < 0.01). Golgi, mitochondrial, dense body and inclusion body fractions were similar in ZD-, PF- and AL-derived cultures.These data suggest that Sertoli cells, although not significantly reduced in number in ZD and PF animals, were affected ultrastructurally by dietary treatment. The volumetric increase in lysosome-like bodies in vivo suggested that Sertoli cells participate in phagocytosis of germ cells degenerating as a result of dietary treatment. The decreased ER volume fraction of ZD-derived tissue cultured Sertoli cells suggested that Sertoli cell secretory potential may be altered as a result of zinc deficiency.