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Articles 1231 - 1260 of 10242
Full-Text Articles in Entire DC Network
Niche Dynamics Of The Felid Guild Following The Pleistocene Megafaunal Extinction, Nicholas A. Freymueller
Niche Dynamics Of The Felid Guild Following The Pleistocene Megafaunal Extinction, Nicholas A. Freymueller
Biology ETDs
The loss of large carnivores is fundamentally restructuring modern mammal communities. However, large carnivore removal is not exclusively a modern trend. The Pleistocene Megafaunal Extinction (PME) resulted in a near-eradication of hyper-carnivorous felids such as saber-toothed cats. However, it is unclear if smaller surviving meso-felids began to infill this ecological vacuum post-PME. I apply Ecological Niche Modeling (ENM) to test evaluate whether surviving felids filled in vacant niches post-extinction, and hypothesize that they ought to have shown increased niche-overlap patterns with mega-felids post-extinction. I model species’ fundamental niches using a multi-temporal approach, and develop a novel test to model realized …
Impact Of Cd82 Expression On Acute Myeloid Leukemia Chemosensitivity And Quiescence, Muskan Floren
Impact Of Cd82 Expression On Acute Myeloid Leukemia Chemosensitivity And Quiescence, Muskan Floren
Biomedical Sciences ETDs
Acute Myeloid Leukemia (AML) patients respond favorably to induction chemotherapy, however, long-term outcomes remain poor due to a high rate of chemoresistance and bone marrow minimal residual disease. To improve long-term patient outcomes, it’s critical to identify regulators of chemotherapy resistance in AML and develop therapies that are directed towards bone marrow resident AML cells. In Chapter 2, we uncover the impact of CD82 expression in AML response to chemotherapeutic treatment and the contribution of Protein Kinase C α (PKCα) and β1 integrin signaling in promoting p38 MAPK activation to support CD82-mediated AML cell survival. In Chapter 3, we …
Understanding The Role Of Atom Trapping In The Evolution Of Hydrocarbon Transformation Catalyst Morphology, Griffin Alexander Canning
Understanding The Role Of Atom Trapping In The Evolution Of Hydrocarbon Transformation Catalyst Morphology, Griffin Alexander Canning
Chemistry and Chemical Biology ETDs
Converting alkanes to other, more chemically and economically valuable molecules requires catalysts that can survive elevated temperatures and highly reducing environments. These environments can cause many metal-nanoparticle based catalysts to sinter rapidly, causing a loss of activity. They must also tolerate the coke formation, as well, since coke can restrict access to active sites by gas phase molecules, thus lowering catalytic activity. While there are routes to improve both the sinter and coke resistance of catalysts, an alternative strategy is to develop a protocol for regenerating the activity of the catalyst in question when coke formation or sintering becomes problematic. …
Climate Change: Increased Potential For Fire Disaster In Taos, New Mexico, Matthew F. Vigil
Climate Change: Increased Potential For Fire Disaster In Taos, New Mexico, Matthew F. Vigil
Climate Change and Public Health Preparedness
No abstract provided.
A New Species Of Ant-Mimicking Sac Spider Castianeira Reiskindi (Araneae: Corinnidae: Castianeirinae) From Nicaragua And A Phylogenetic Analysis Of The Australian Castianeirinae, Matthew P. Leister
A New Species Of Ant-Mimicking Sac Spider Castianeira Reiskindi (Araneae: Corinnidae: Castianeirinae) From Nicaragua And A Phylogenetic Analysis Of The Australian Castianeirinae, Matthew P. Leister
Biology ETDs
Ant-mimicking spiders in the subfamily Castianeirinae have had a number of taxonomic revisions and species descriptions. Despite these advancements, more species exist await formal scientific description and little scientific progress has been made in terms of reconstructing their evolutionary histories. This study 1) describes a new species Castianeira reiskind sp. n. from cloud forests in Nicaragua; and 2) presents a first look of the Australian Castianeirinae taxa in a phylogenetic framework. This analysis is used to explore the origins of Hymenoptera mimicry in this group, test the monophyly of this subfamily compared to the Corinninae and to test the current …
The Effects Of Glycosylation On Immunogenicity And Replication Of Emerging Viral Pathogens, Elizabeth Carvosso Clarke
The Effects Of Glycosylation On Immunogenicity And Replication Of Emerging Viral Pathogens, Elizabeth Carvosso Clarke
Biomedical Sciences ETDs
For filoviruses, a family of hemorrhagic fever viruses, the main antigen for vaccines in development is the glycosylated glycoprotein GP1,2. How the glycosylation of GP1,2 differs when the protein is produced in different cell lines is unclear. We showed significant differences in the types of glycans conferred onto filovirus GP1,2s in produced in mammalian-origin and insect-origin cell lines. Mammalian-derived filovirus GP1,2s have diverse N-linked glycans and extensive O-linked glycans, whereas insect-derived filovirus GP1,2s have N-linked glycans that are primarily paucimannose type and have no observable O-linked glycans. We then showed that differences in glycosylation impacted how immunogenic the proteins were …
Ibram X. Kendi's How To Be An Antiracist, Quatez Scott
Ibram X. Kendi's How To Be An Antiracist, Quatez Scott
Intersections: Critical Issues in Education
This book review of Ibram X. Kendi’s How to Be an Antiracist (2019) addresses the importance of exploring race relations in the U.S. from a framework that focuses on racial policies. Commonly referred to as “systemic racism” and “institutional racism”, racist policies maintain racial inequities. Antiracists aim to eliminate those racial policies. Kendi’s ability to address these issues head on with deeply researched historical narratives brings light to the ways racial policies are reinforced, which reproduce racist ideas. This book drives straight to the heart of racial challenges and takes a new approach at examining how and why humans should …
New Mexico: Land Of The Drought, Brandi Davis
New Mexico: Land Of The Drought, Brandi Davis
Climate Change and Public Health Preparedness
No abstract provided.
Adverse Event Reporting For Cellular Therapy Products: Current Status And Future Directions, Kathy Loper, Michele W. Sugrue, Jay S. Raval, Joseph Yossi Schwartz, Kevin Land, Mickey Koh, Thilo Mengling, Hildegard Greinix, Jörg P. Halter, Christina M Celluzzi, Maysum Chaudhri
Adverse Event Reporting For Cellular Therapy Products: Current Status And Future Directions, Kathy Loper, Michele W. Sugrue, Jay S. Raval, Joseph Yossi Schwartz, Kevin Land, Mickey Koh, Thilo Mengling, Hildegard Greinix, Jörg P. Halter, Christina M Celluzzi, Maysum Chaudhri
Pathology Research and Scholarship
Adverse event (AE) and adverse reaction (AR) reporting are key components of patient safety and surveillance systems. Review and analysis of this data yields opportunities for process improvement, product information and interventions, and can lead to improved patient outcomes and donor safety overall. AE and AR reporting for cellular therapy products is fragmented and not well characterized in a central reference. This review article, authored by experts from various organizations, serves to summarize the current state of reporting and offers opportunities for streamlining and coordination, as well as key reference for professionals in this field.
Evolution Of The Epigenetic Landscape In Childhood B Acute Lymphoblastic Leukemia And Its Role In Drug Resistance, Shella Saint Fleur-Lominy, Nikki A. Evensen, Teena Bhatla, Gunjan Sethia, Sonali Narang, Jun H. Choi, Xiaotu Ma, Jun J. Yang, Stephen Kelly, Elizabeth Raetz, Richard C. Harvey, Cheryl Willman, Mignon L. Loh, Stephen P. Hunger, Patrick A. Brown, Kylie M. Getz, Cem Meydan, Christopher E. Mason, Aristotelis Tsirigos, William Carroll
Evolution Of The Epigenetic Landscape In Childhood B Acute Lymphoblastic Leukemia And Its Role In Drug Resistance, Shella Saint Fleur-Lominy, Nikki A. Evensen, Teena Bhatla, Gunjan Sethia, Sonali Narang, Jun H. Choi, Xiaotu Ma, Jun J. Yang, Stephen Kelly, Elizabeth Raetz, Richard C. Harvey, Cheryl Willman, Mignon L. Loh, Stephen P. Hunger, Patrick A. Brown, Kylie M. Getz, Cem Meydan, Christopher E. Mason, Aristotelis Tsirigos, William Carroll
Pathology Research and Scholarship
Although B-cell acute lymphoblastic leukemia (B-ALL) is the most common malignancy in children and while highly curable, it remains a leading cause of cancer-related mortality. The outgrowth of tumor subclones carrying mutations in genes responsible for resistance to therapy has led to a Darwinian model of clonal selection. Previous work has indicated that alterations in the epigenome might contribute to clonal selection, yet the extent to which the chromatin state is altered under the selective pressures of therapy is unknown. To address this, we performed chromatin immunoprecipitation, gene expression analysis, and enhanced reduced representation bisulfite sequencing on a cohort of …
Role Of Β-Glucan Structure In Dectin-1 Homo- And Hetero-Oligomerization In Innate Anti-Fungal Immunity, Eduardo U. Anaya
Role Of Β-Glucan Structure In Dectin-1 Homo- And Hetero-Oligomerization In Innate Anti-Fungal Immunity, Eduardo U. Anaya
Biomedical Sciences ETDs
Dectin-1A is a C-type Lectin innate immunoreceptor that recognizes β-(1,3)-glucan, a structural component of Candida species cell walls. Dectin-1 has eight alternative splice isoforms including, A and B. Innate immunocytes can express one or both isoforms, but neither their relative responsiveness to β-glucan nor the potential for inter-isoform signaling cross-talk is well understood. In this study, we determine how the different structures of soluble β-glucans affect both isoforms and unravel how differences in glucan structure impact the earliest events in Dectin-1 signaling. Using quantitative microscopy techniques, we explored the role of glucan structure on Dectin-1A oligomerization, which is thought to …
Through The Funnel: A Critical Policy Analysis Of Educational Policy Relating To The School-To-Prison Pipeline., Jesse V. Hall
Through The Funnel: A Critical Policy Analysis Of Educational Policy Relating To The School-To-Prison Pipeline., Jesse V. Hall
Special Education ETDs
The purpose of the present study involved analyzing the policies of the Trump administration to determine the ways it impacted the school-to-prison pipeline. The focus of the study included the Departments of Education and Justice. The findings revealed educational policies and deregulatory practices that maintained and intensified the school-to-prison pipeline.
Introduction To Neutrosophic Genetics, Florentin Smarandache
Introduction To Neutrosophic Genetics, Florentin Smarandache
Branch Mathematics and Statistics Faculty and Staff Publications
Neutrosophic Genetics is the study of genetics using neutrosophic logic, set, probability, statistics, measure and other neutrosophic tools and procedures. In this paper, based on the Neutrosophic Theory of Evolution (that includes degrees of Evolution, Neutrality (or Indeterminacy), and Involution) – as extension of Darwin’s Theory of Evolution, we show the applicability of neutrosophy in genetics, and we present within the frame of neutrosophic genetics the following concepts: neutrosophic mutation, neutrosophic speciation, and neutrosophic coevolution.
Neutrosophic Sets And Systems, Vol. 38, 2020, Florentin Smarandache, Mohamed Abdel-Basset, Said Broumi
Neutrosophic Sets And Systems, Vol. 38, 2020, Florentin Smarandache, Mohamed Abdel-Basset, Said Broumi
Neutrosophic Sets and Systems
No abstract provided.
Chemical Interfacial Reactions Affecting The Speciation And Solubility Of Uranium In Organic-Rich Environments, Carmen A. Velasco
Chemical Interfacial Reactions Affecting The Speciation And Solubility Of Uranium In Organic-Rich Environments, Carmen A. Velasco
Civil Engineering ETDs
The aim of this dissertation was to investigate the interfacial reactions between uranium (U) and natural organic matter NOM) affecting the solubility, adsorption, and precipitation of U in organic-rich environments. The chemical interactions between U and NOM are not well understood, which justified the following research objectives: 1) Identify the effect of pH on U speciation and the organic functional chemistry in mineralized deposits from the Jackpile Mine.; 2) Identify the precipitation of U(VI) and NOM as a function of pH (2, 4 and 7); 3) Identify changes in DOM chemistry due to the reaction of NOM and U at …
Boron Adsorption In Clay Minerals: Implications For Martian Groundwater Chemistry And Prebiotic Processes, Matthew A. Nellessen, Laura Crossey, Patrick J. Gasda, Horton Newsom, Abdulmehdi Ali, Eric J. Peterson, Nina Lanza, Adriana Reyes-Newell, Dorothea Delapp, Chris Yeager, Andrea Labouriau, Roger C. Wiens, Samuel Clegg, Shelbie Legett, Debarati Das
Boron Adsorption In Clay Minerals: Implications For Martian Groundwater Chemistry And Prebiotic Processes, Matthew A. Nellessen, Laura Crossey, Patrick J. Gasda, Horton Newsom, Abdulmehdi Ali, Eric J. Peterson, Nina Lanza, Adriana Reyes-Newell, Dorothea Delapp, Chris Yeager, Andrea Labouriau, Roger C. Wiens, Samuel Clegg, Shelbie Legett, Debarati Das
Earth and Planetary Sciences ETDs
Boron has been detected on Mars [Gasda et al., 2017, Das et al., 2019, 2020] within calciumsulfate veins found within clay-rich rocks on Mars by the Mars Science Laboratory (MSL) rover using Laser Induced Breakdown Spectroscopy (LIBS) analysis. Boron plays a vital role in stabilizing ribose on Earth and has been suggested as a key requirement for life [Scorei et al., 2006, 2012; Furukawa et al., 2013, 2017; Becker et al., 2019]. Additionally, boron readily adsorbs to phyllosilicate clay minerals and is often associated with biologic processes in clay soils. The discovery of boron on Mars in proximity to phyllosilicate …
Introduction To Neutrohypergroups, M. A. Ibrahim, A. A.A. Agboola
Introduction To Neutrohypergroups, M. A. Ibrahim, A. A.A. Agboola
Neutrosophic Sets and Systems
No abstract provided.
Atom Trapping And Its Role On The Nucleation & Growth Of Platinum Nanoparticles, Deepak Kunwar
Atom Trapping And Its Role On The Nucleation & Growth Of Platinum Nanoparticles, Deepak Kunwar
Chemistry and Chemical Biology ETDs
Diesel oxidation catalysts deactivate due to Pt sintering, a major problem in automotive industries. To make sure they operate effectively throughout the lifetime of the vehicle, automotive industries are putting an excessive amount of Pt. There is a need to develop a catalyst that serves long term performance with minimal use of Pt. Jones et al.1 demonstrated that ceria traps Pt atoms. His work generated some logical and valid questions such as what is the mechanism for the formation of anomalously large Pt particles? What is the upper limit of Pt metal loading in the form of single atoms …
Radial Basis Densities And The Density Functional-Based Atom-In-Molecule: Designing Charge-Transfer Potentials, Godwin Amo-Kwao
Radial Basis Densities And The Density Functional-Based Atom-In-Molecule: Designing Charge-Transfer Potentials, Godwin Amo-Kwao
Nanoscience and Microsystems ETDs
Classical potentials that are capable of describing charge transfer and charge polarization in complex systems are of central importance for classical atomistic simulation of biomolecules and materials. Current potentials—regardless of the system—do not generalize well, and, with the exception of highly-specialized empirical potentials tuned for specific systems, cannot describe chemical bond formation and breaking. The charge-transfer embedded atom method (CT-EAM), a formal, DFT-based extension to the original EAM for metals, has been developed to address these issues by modeling charge distortion and charge transfer in interacting systems using pseudoatom building blocks instead of the electron densities of isolated atoms. CT-EAM …
Evolution Of Brain-Wide Activity In The Awake Behaving Mouse After Acute Fear By Longitudinal Manganese-Enhanced Mri, Taylor W. Uselman, Daniel R. Barto, Russell E. Jacobs, Elaine L. Bearer
Evolution Of Brain-Wide Activity In The Awake Behaving Mouse After Acute Fear By Longitudinal Manganese-Enhanced Mri, Taylor W. Uselman, Daniel R. Barto, Russell E. Jacobs, Elaine L. Bearer
Pathology Research and Scholarship
Life threatening fear after a single exposure evolves in a subset of vulnerable individuals to anxiety, which may persist for their lifetime. Yet neither the whole brain's response to innate acute fear nor how brain activity evolves over time is known. Sustained neuronal activity may be a factor in the development of a persistent fear response. We couple two experimental protocols to provoke acute fear leading to prolonged fear: Predator stress (PS), a naturalistic approach to induce fear in rodents; and Serotonin transporter knockout mouse (SERT-KO) that responds to PS with sustained defensive behavior. Behavior was monitored before, during and …
Chad: Human Fertility, Crop Production And Changing Weather Patterns, Jake Organ
Chad: Human Fertility, Crop Production And Changing Weather Patterns, Jake Organ
Economics ETDs
The subject of this dissertation is the effect of changing weather patterns on human fertility in Chad, Sahelian Africa. There is a body of literature on the effect of extreme weather events-usually associated with large-scale mortality-and human fertility. However, there is less of a body of literature on the effects of less extreme changing weather patterns and human fertility. Chad has known substantial warming since the late 1960s, hence I use rising heat as a proxy for changing weather patterns. Using GIS-coded fertility and weather data, I look for correlations between the birth rate and the number of days in …
A Bayesian Network Analysis Of The Human Exposure To Escherichia Coli Bacteria In The Environment, Brandon G. De Flon
A Bayesian Network Analysis Of The Human Exposure To Escherichia Coli Bacteria In The Environment, Brandon G. De Flon
Mathematics & Statistics ETDs
Diarrhea is a leading cause of death worldwide because a lack thereof in household sanitization exposes humans to high concentrations of pathogenic Escherichia coli. In 2016, the University of New Mexico’s Nepal Study Center collected cross-sectional survey data using proportional random sampling on three communities in Western Nepal. Structural and parameter learning estimation and approximate inference of Bayesian networks studied diarrheagenic E. coli exposure while incorporating participation in sanitary behaviors, access to sanitary built-in environments, and other human characteristics. Of the reported sickness, hand washing resulted in a 20 percent decrease, water treatment 8 percent, and both 28 percent. Of …
Integrating Deep Learning And Augmented Reality To Enhance Situational Awareness In Firefighting Environments, Manish Bhattarai
Integrating Deep Learning And Augmented Reality To Enhance Situational Awareness In Firefighting Environments, Manish Bhattarai
Electrical and Computer Engineering ETDs
We present a new four-pronged approach to build firefighter's situational awareness for the first time in the literature. We construct a series of deep learning frameworks built on top of one another to enhance the safety, efficiency, and successful completion of rescue missions conducted by firefighters in emergency first response settings. First, we used a deep Convolutional Neural Network (CNN) system to classify and identify objects of interest from thermal imagery in real-time. Next, we extended this CNN framework for object detection, tracking, segmentation with a Mask RCNN framework, and scene description with a multimodal natural language processing(NLP) framework. Third, …
Social Network Centrality, Social Construction Of Knowledge, And Nurse Practitioner Competency In Asynchronous Online Discussions Among Adult Gerontology Acute Care Nurse Practitioner Students, Sharon Schaaf
Organization, Information and Learning Sciences ETDs
The relationships between social network centrality, social construction of knowledge, and nurse practitioner competency among adult gerontology acute care nurse practitioner students participating in asynchronous online discussions were explored. Social network centralities (betweenness, in-degree, out-degree, closeness, and eigenvector) were determined through social network analysis. Social construction of knowledge was assessed by the Interaction Analysis Model (IAM). Nurse practitioner competency was evaluated using the Novice to Expert model. A retrospective exploration of an online discussion board from the College of Nursing at the University of New Mexico was conducted. The centralities of betweenness, closeness, and eigenvector demonstrated a significant relationship with …
From Wave Propagation To Spin Dynamics: Mathematical And Computational Aspects, Oleksii Beznosov
From Wave Propagation To Spin Dynamics: Mathematical And Computational Aspects, Oleksii Beznosov
Mathematics & Statistics ETDs
In this work we concentrate on two separate topics which pose certain numerical challenges. The first topic is the spin dynamics of electrons in high-energy circular accelerators. We introduce a stochastic differential equation framework to study spin depolarization and spin equilibrium. This framework allows the mathematical study of known equations and new equations modelling the spin distribution of an electron bunch. A spin distribution is governed by a so-called Bloch equation, which is a linear Fokker-Planck type PDE, in general posed in six dimensions. We propose three approaches to approximate solutions, using analytical and modern numerical techniques. We also present …
Inoculum Potential Of Pinus Edulis-Associated Ectomycorrhizal Fungi Across A Forest Extirpation Chronosequence, Annie M. Montes
Inoculum Potential Of Pinus Edulis-Associated Ectomycorrhizal Fungi Across A Forest Extirpation Chronosequence, Annie M. Montes
Biology ETDs
Few studies have examined inoculum potential of ectomycorrhizal fungi (EMF) in the absence of plant hosts, yet persistence of these fungi may be paramount to resilience of Pinus edulis and other mycorrhizal plant species. We conducted a study in which seven sites were selected in northwestern New Mexico with known dates of P. edulis extirpation and a lack of regeneration. Age classes included: two sites extirpated 10-20 years ago, two extirpated 55-65 years ago, two extirpated 500+ years ago, and one extirpated 11,000+ years ago. At each site, two plots were paired: an extirpated plot and the nearest live adult …
Spatio-Temporal Dynamics Of Fungal Communities And Their Effects On Plants, Kel Cook
Spatio-Temporal Dynamics Of Fungal Communities And Their Effects On Plants, Kel Cook
Biology ETDs
Fungi perform several critical functions in the environment. Spatiotemporal distributions of fungal communities will mediate when and where these functions happen and how they vary across the landscape. I first explored tropical tree canopy fungal community variation at small spatial scales and documented near total turnover of fungi across sub-meter distances and among adjacent substrates. The second chapter analyzed fungal turnover over the course of three years, where community stability was driven primarily by abundant fungi. In the third chapter, I tested effects of the environment, including host plant and habitat, on canopy fungal communities and found only small effects, …
Gan Nanowire Laser For A Universal Atomic Force Microscope Probe: A Computational And Feasibility Study, Neal Wostbrock
Gan Nanowire Laser For A Universal Atomic Force Microscope Probe: A Computational And Feasibility Study, Neal Wostbrock
Nanoscience and Microsystems ETDs
This thesis attempts to establish the groundwork for integrating a GaN nanowire into an AFM probe resulting in a universal atomic force microscope probe. Previous studies have shown GaN nanowires have stable mechanical properties, can be fabricated at scale with high aspect ratios and very smooth side walls, and have intrinsic lasing capabilities; however, mechanical and lasing capabilities have not yet been integrated into a single AFM probe. Here, we develop and analyze a suspended waveguide optical pumping concept that can be fabricated and applied to an AFM probe cantilever, unlocking full potential of GaN’s optical and mechanical properties as …
The Experience Of Being Gender Nonbinary: An Interpretative Phenomenological Analysis, Gene Crofts
The Experience Of Being Gender Nonbinary: An Interpretative Phenomenological Analysis, Gene Crofts
Individual, Family, and Community Education ETDs
The call for research on the growing population of persons who identify as gender nonbinary includes the need for in-depth explorations of lived experience, especially among Persons of Color. This study focuses on four individuals, 27 to 32 years of age, who identify as gender nonbinary as well as Hispanic/Latinx and reside in the unique minority-majority, conservative/progressive state of New Mexico. Interpretative phenomenological analysis, with its idiographic approach, was used to gather data through interviews and present the findings in both descriptive and interpreted terms. Results focus on three themes: realization required a unique journey, allowances are made for mothers …
Mucosal Immune System Of African Lungfish, Ryan D. Heimroth
Mucosal Immune System Of African Lungfish, Ryan D. Heimroth
Biology ETDs
Conquering land was an apex moment in the evolution of vertebrates. Physiologically, the first vertebrates to transition to life on land had to adapt in order to survive in an oxygen-rich environment where gravitational forces and limited water prevailed. Several extant vertebrates including anurans and lungfish, survive droughts by undergoing aestivation. Unfavorable environmental conditions trigger lungfish to aestivate. Aestivation is a process of metabolic torpor wherein the fish will encase itself in a mucus cocoon and not move until favorable environmental conditions (food and water) are reintroduced. Aestivation can be reproduced in laboratory settings and, thus, lungfish can be used …