Digital Commons Network^™

Noninvasive Vagus Nerve Stimulation Reduces Brain Lesion Volume In A Rat Model Of Traumatic Brain Injury, Afshin A. Divani, Erik Taylor, Hafiz Abdullha Ikram, Pascal Salazar, Yirong Yang, Karen Santacruz, Onamma A. Edeh, Denis E. Bragin

Brain & Behavioral Health Research Day

Background: Traumatic brain injury (TBI) continues to be a major cause of death and disability. Vagus nerve stimulation (VNS) has been shown to reduce proinflammatory responses in TBI models. We assessed the effect of a non-invasive VNS (nVNS) on reducing the lesion volume in a rat model of TBI.

Methods: TBI was induced using a standard CCI (Impact one, Leica) model. Rats were randomized into three groups: TBI control, TBI treated with five 2-min nVNS stimulations, and TBI treated with five 2x2-min nVNS stimulations using the gammaCore device was initiated 30 minutes post-TBI (10 minutes interval between each stimulation). MRI …

Understanding Mild Cognitive Impairment, Ron Epps, Chris Chaffin, Tim Sheahan, Craig Coleman

Brain & Behavioral Health Research Day

The Alzheimer’s Association, New Mexico Chapter is a nonprofit that provides support, fundraising and advocacy on behalf of the 43,000 New Mexicans with Alzheimer’s disease and their 85,000 unpaid family caregivers. Our Chapter is a community-based, volunteer-driven 501(c) (3) nonprofit that maximizes collaboration with other public and private agencies; and relies primarily upon funding from private individuals, foundations and corporations to meet the needs created by the growing Alzheimer’s epidemic. Our vision: a world without Alzheimer's and all other dementia. Our mission: The Alzheimer's Association leads the way to end Alzheimer's and all other dementia — by accelerating global research, …

Impact Of Isolation During The Covid-19 Pandemic On Non-Motor Symptoms Of Parkinson’S Disease: A Pmd Alliance Survey, Neal Hermanowicz, Maria Cristina Ospina, Yasar Torres-Yaghi, Sherrie Gould, Kelly Papesh, Jason Rivera, Susan Miller, Sarah Jones, Kelli Musick, Damian May

Brain & Behavioral Health Research Day

Introduction: Social isolation impairs physical and mental health, particularly among the elderly. As Parkinson’s disease (PD) usually affects the elderly, we hypothesized that social isolation during the COVID-19 pandemic could exacerbate non-motor symptoms of PD. This survey aimed to assess the impact of social isolation on self- or proxy-reported symptoms PD during the COVID-19 pandemic.

Methods: The survey was distributed online between 01/06/21 and 02/27/21 among 7,109 subscribers of the Parkinson and Movement Disorders Alliance (PMD Alliance) newsletter. It was open only to people with PD (PwP) and Care Partners (CP, defined as main caregivers of PwP, and serving as …

The Influence Of Maternal-Child Interactions During Early Child Development And The Impact On Anterior Cingulate Cortex Volumes, Sofia Markee, Dawn Novak, John Philips, Kati N. Baillie, Tiffany Emery, Jean Lowe

Brain & Behavioral Health Research Day

Background: Studies investigating differences in regional brain volumes in children during early childhood are limited. Many theories suggest the anterior cingulate cortex (ACC) is at the center of the brain’s self-regulatory system playing a key role in learning and emotion. Our aim is to investigate the volume of the ACC identified with MRI and developmental outcomes in children at 18 months. We hypothesize the volume of the ACC will be larger in children who received more positive directing behaviors from their mothers during play and ACC volumes will be larger in children with higher cognitive and language scores as measured …

Third Trimester-Equivalent Ethanol Exposure Decreases Neuronal Numbers In The Antero-Ventral And Reticular Nuclei Of The Thalamus Of Adolescent Male Mice, Stephanie Mayfield, G Jill Chavez, Clark Bird, C Fernando Valenzuela

Brain & Behavioral Health Research Day

Fetal alcohol exposure is a pervasive cause of intellectual disability. The range of effects caused by prenatal ethanol exposure are grouped under the umbrella term, Fetal Alcohol Spectrum Disorders (FASDs). Exposure to alcohol during any period of pregnancy can damage the fetal brain, including the last trimester of pregnancy, where the brain growth spurt takes place. Ethanol exposure during late pregnancy produces learning and memory deficits that can last into adulthood. Studies suggest that these deficits may be a consequence of damage to the posterior limbic memory system. This system includes specialized neuronal populations in several connected regions: the subiculum, …

Unm Health Sciences Center Data Book 2021-22, University Of New Mexico - Health Sciences Center

Health Sciences Center Databook (1990-ongoing)

No abstract provided.

Project Echo Annual Report 2022, University Of New Mexico, Health Sciences Center, Project Echo Communications Team

Project ECHO Annual Reports

No abstract provided.

University Of New Mexico Health Sciences Center Discovery Research Annual Report 2022, Michael Haederle, Sara Mota, El Webb, Chris Corrie, Byron Hughey-Geer, Jett Loe, Sarah Head, Elizabeth Sandlin

Research Annual Reports

No abstract provided.

Response: Commentary: Evaluating Sensory Integration/Sensory Processing Treatment: Issues And Analysis, Sarah A Schoen, Roseann C Schaaf, Zoe Mailloux, Anita Bundy, Shelly Lane, Teresa A May-Benson, L Diane Parham, Susanne Smith Roley

Pediatrics Research and Scholarship

No abstract provided.

Mental Health And Online Learning - Systematic Review Dataset, Stephanie L. Moore Phd, George Veletsianos, Michael Barbour

University Libraries & Learning Sciences Faculty and Staff Publications

While there has been a lot of debate over the impact of online and remote learning on mental health and well-being, there has been no systematic syntheses or reviews of the research on this particular issue. In this paper, we review the research on the relationship between mental health / well-being and online or remote learning. Our review shows that little scholarship existed prior to 2020 with most studies conducted during the COVID-19 pandemic. We report four findings: (a) pandemic effects are not well-controlled for in most studies; (b) studies present a very mixed picture, with variability around how mental …

Integrins As Therapeutic Targets For Sars-Cov-2, Timothy E. Gressett, Danielle Nader, Juan Pablo Robles, Tione Buranda, Steven W. Kerrigan, Gregory Bix

Pathology Research and Scholarship

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is an enveloped, positive-sense, single-stranded RNA virus of the genus Betacoronavirus. Its genome is composed of four structural proteins known as spike (S), envelope (E), membrane (M), and nucleocapsid (N), of which E, M, and N are integrated into the viral envelope. The S glycoprotein, which protrudes from the surface of mature virions as a spike, is essential for virus attachment, fusion, and entry into the host cell. While the relationship between the spike protein of SARS-CoV-2 and the angiotensin- converting enzyme 2 (ACE2) receptor has been readily established, the S1 subunit also …

The Giant Axon Of The Squid: A Simple System For Axonal Transport Studies, Joseph A. Degiorgis, Marcus Jang, Elaine L. Bearer

Pathology Research and Scholarship

The squid giant axon has a long history of being a superb experimental system in which to investigate a wide range of questions concerning intracellular transport. In this protocol we describe the method used for dissecting the axon to preserve its viability in vitro, and the technique for injecting exogenous materials into the living axon. Now that the squid genome is emerging, and the CRISPR/cas9 system has been successfully applied to knock-out squid genes, the giant axon will resume its place in the scientific pantheon of powerful experimental systems in which to address biological questions pertaining to all eukaryotes.

Reduced Cleavage Of Von Willebrand Factor By Adamts13 Is Associated With Microangiopathic Acute Kidney Injury Following Trauma, William E. Plautz, Shannon H. Haldeman, Mitchell R. Dyer, Jason L. Sperry, Francis X. Guyette, Patricia A. Loughran, Jurgis Alvikas, Adnan Hassoune, Lara Hoteit, Nijmeh Alsaadi, Brian S. Zuckerbraun, Marian A. Rollins-Raval, Jay S. Raval, Roberto I. Mota, Matthew D. Neal

Pathology Research and Scholarship

Acute kidney injury (AKI) is common after trauma, but contributory factors are incompletely understood. Increases in plasma von Willebrand Factor (vWF) with concurrent decreases in ADAMTS13 are associated with renal microvascular thrombosis in other disease states, but similar findings have not been shown in trauma. We hypothesized that molecular changes in circulating vWF and ADAMTS13 promote AKI following traumatic injury. VWF antigen, vWF multimer composition and ADAMTS13 levels were compared in plasma samples from 16 trauma patients with and without trauma-induced AKI, obtained from the Prehospital Air Medical Plasma (PAMPer) biorepository. Renal histopathology and function, vWF and ADAMTS13 levels were …

A Deep Learning Convolutional Neural Network Can Differentiate Between Helicobacter Pylori Gastritis And Autoimmune Gastritis With Results Comparable To Gastrointestinal Pathologists, Michael M. Franklin, Fred A. Schultz, Marissa A. Tafoya, Audra A. Kerwin, Cory J. Broehm, Edgar G. Fischer, Rama R. Gullapalli, Douglas P. Clark, Joshua A. Hanson, David R. Martin

Pathology Research and Scholarship

CONTEXT.—: Pathology studies using convolutional neural networks (CNNs) have focused on neoplasms, while studies in inflammatory pathology are rare. We previously demonstrated a CNN that differentiates reactive gastropathy, Helicobacter pylori gastritis (HPG), and normal gastric mucosa.

OBJECTIVE.—: To determine whether a CNN can differentiate the following 2 gastric inflammatory patterns: autoimmune gastritis (AG) and HPG.

DESIGN.—: Gold standard diagnoses were blindly established by 2 gastrointestinal (GI) pathologists. One hundred eighty-seven cases were scanned for analysis by HALO-AI. All levels and tissue fragments per slide were included for analysis. The cases were randomized, 112 (60%; 60 HPG, 52 AG) in the …

Cultural Identity Central To Native American Persistence In Science., Nizhoni Chow-Garcia, Naomi Lee, Vanessa Svihla, Claira Sohn, Scott Willie, Maija Holsti, Angela Wandinger-Ness

Pathology Research and Scholarship

Native Americans are the least represented population in science fields. In recent years, undergraduate and graduate level summer research programs that aimed to increase the number of Native Americans in science have made some progress. As new programs are designed, key characteristics that address science self-efficacy and science identity and provide supports for Native American students' commitment to a scientific career should be considered. In this study, we used sequential mixed methods to investigate the potential of culturally tailored internship programs on Native American persistence in science. We analyzed surveys (n = 47) and interviews (n = 4) …

Spmdtu Strategic Plan 2, José Rivera

03. Selected Minutes and Reports

No abstract provided.

From Logic To Realism To Brighter Future For Humanity, Victor Christianto, Florentin Smarandache

Branch Mathematics and Statistics Faculty and Staff Publications

This collection of published papers at International Journal of Neutrosophic Science actually began with just a simple request by Dr. Broumi Said, the editor of IJNS, to us, to submit an article for his new journal. Then we submitted a series of new articles discussing various applications of Neutrosophic Logic, a new kind of logic as developed by one of us (FS). We explore a wide range of subject, from Godel’s incompleteness theorem, to possible technocalypse and neutro-futurology, and also additional sections. Hopefully you will find these articles interesting for better understanding of nature.

“Who Is Eating Whom?”: Wet Nursing And White Cannibalism In Brazil, Grace Sparapani

Hemisphere: Visual Cultures of the Americas

No abstract provided.

Medical Residency Milestones: Competencies In Informatics, Library, And Evidence-Based Practice, Deborah J. Rhue, Jonathan Eldredge

Publications

The Accreditation Council for Graduate Medical Education (ACGME) sets standards known as Milestones and monitors the progress of medical residents as they advance toward medical practice in their specialties. Health sciences librarians need to train medical residents in certain competency areas to help reach the Milestone standards. This project analyzed the Milestones related to informatics, library, and Evidence Based Practice (EBP) skills to identify core and optional library-related curricular elements that can be integrated into different medical specialty residencies.

The authors collected key competency documents from ACGME and from those specialties representing 2% or more of the residencies in the …

Health Sciences Library And Informatics Center Strategic Plan Fy22-Fy24, Health Sciences Library And Informatics Center

HSLIC Strategic Plans

This document is the UNM Health Sciences Library and Informatics Center's strategic plan for FY2022 – FY2024.

Linguistic Matrices, W. B. Vasantha Kandasamy, K. Ilanthenral, Florentin Smarandache

Branch Mathematics and Statistics Faculty and Staff Publications

The authors build linguistic matrices only for those linguistic variables which yield a linguistic continuum or an ordered linguistic set. Most of the properties enjoyed by real and complex matrices are satisfied by these linguistic matrices. However, we see when we try to define operations on linguistic matrices that they behave in different ways. The possible operations defined on linguistic matrices are only the maximum and minimum. Further, we have different identities for min and max operations on these matrices for linguistic variable and its associated linguistic words.

Collected Papers (On Neutrosophic Theory And Applications), Volume Vii, Florentin Smarandache

Branch Mathematics and Statistics Faculty and Staff Publications

This seventh volume of Collected Papers includes 70 papers comprising 974 pages on (theoretic and applied) neutrosophics, written between 2013-2021 by the author alone or in collaboration with 122 co-authors from 22 countries.

Collected Papers (On Physics, Artificial Intelligence, Health Issues, Decision Making, Economics, Statistics), Volume Xi, Florentin Smarandache

Branch Mathematics and Statistics Faculty and Staff Publications

This eleventh volume of Collected Papers includes 90 papers comprising 988 pages on Physics, Artificial Intelligence, Health Issues, Decision Making, Economics, Statistics, written between 2001-2022 by the author alone or in collaboration with 84 co-authors from 19 countries.

Collected Papers (On Neutrosophics, Plithogenics, Hypersoft Set, Hypergraphs, And Other Topics), Volume X, Florentin Smarandache

Branch Mathematics and Statistics Faculty and Staff Publications

This tenth volume of Collected Papers includes 86 papers in English and Spanish languages comprising 972 pages, written between 2014-2022 by the author alone or in collaboration with 105 co-authors from 26 countries.

Collected Papers (Neutrosophics And Other Topics), Volume Xiv, Florentin Smarandache

Branch Mathematics and Statistics Faculty and Staff Publications

This fourteenth volume of Collected Papers is an eclectic tome of 87 papers in Neutrosophics and other fields, such as mathematics, fuzzy sets, intuitionistic fuzzy sets, picture fuzzy sets, information fusion, robotics, statistics, or extenics, comprising 936 pages, published between 2008-2022 in different scientific journals or currently in press, by the author alone or in collaboration with 99 co-authors from 26 countries.

Analyzing The Sustainability Of Industry Affected In Covid-19 Pandemic Scenario Using Cosine Similarity Measure Under Svpns And Pnn Model, Priyanka Majumder, Florentin Smarandache

Branch Mathematics and Statistics Faculty and Staff Publications

COVID-19 outbreak is a reminder of the fact that the pandemics have happened in the past and will also occur in the future. The COVID-19 not only has affected the economy; but also it has affected the livelihood, which leads to the changes in businesses. This study aims to identify the most significant indicator (or parameter) that impacts the sustainability of industries. The study should also develop a realtime monitoring system for the sustainability of industries affected by COVID 19. In this work, the Polynomial Neural Network (PNN) and cosine similarity measure under SVPNS (Single-Valued Pentapartitioned Neutrosophic Set) environment have …

Santa Fe Midtown Community Engagement, Michaele Pride, Hally Bert, Emily Ontiveros, Kathleen Gygi, Alex Streeper, Gabriel De Pablo

Design and Planning Assistance Center - Projects

DPAC was contracted by the City of Santa Fe to facilitate public engagement to inform the master plan and redevelopment of Santa Fe Midtown. We worked with Midtown Engagement Partners (MEPs), the City of Santa Fe, local design teams, and the Strategic Economics/Opticos team, among others, on a distributed model of public engagement, combining diverse methods to gather input from the public. Together, we organized listening and planning sessions, site visits, a block party and posolada, online conversations, and interactive planning exercises. This work revealed a common vision for belonging, culture, equitable development, and environmental and community health.

Injuries In Food Growers: Are There Gender Differences?, Patricia Siegel, Marcy Rinaldi

OT Research and Scholarship

According to the Centers for Disease Control (CDC) agriculture is one of the most hazardous industries in the United States (2021). Data shows the prevalence of musculoskeletal disorders in farmers is high, with a lifetime prevalence of any form of musculoskeletal disorder at 90.6% (Osborne et. al., 2012). Men tend to be injured more often especially when working with farm machinery (Dimich-Ward et. al., 2004). Animal related injuries dominated for women (Dimich-Ward et. al., 2004). This research suggests that farming injuries could be different depending on the gender of the worker and the work they do.

Biomedical Informatics Seminar Series (Biomiss) 2022, Jonathan Eldredge, Gale Hannigan, Brandon Carroll

Biomedical Informatics Seminar Series (BioMISS)

No abstract provided.

Cancer Vaccines From Cryogenically Silicified Tumour Cells Functionalized With Pathogen-Associated Molecular Patterns, Jimin Guo, Henning De May, Stefan Franco, Achraf Noureddine, Lien Tang, C J. Brinker, Donna F. Kusewitt, Sarah F. Adams, Rita E. Serda

Pathology Research and Scholarship

The production of personalized cancer vaccines made from autologous tumour cells could benefit from mechanisms that enhance immunogenicity. Here we show that cancer vaccines can be made via the cryogenic silicification of tumour cells, which preserves tumour antigens within nanoscopic layers of silica, followed by the decoration of the silicified surface with pathogen-associated molecular patterns. These pathogen-mimicking cells activate dendritic cells and enhance the internalization, processing and presentation of tumour antigens to T cells. In syngeneic mice with high-grade ovarian cancer, a cell-line-based silicified cancer vaccine supported the polarization of CD4⁺ T cells towards the T-helper-1 phenotype in the …