Digital Commons Network^™

Southwestern Acequia Systems And Communities; Nurturing A Culture Of Place, Eric Romero

Natural Resources Journal

El Aqua es La Vida” (Water is Life) is a ubiquitous bumper sticker on trucks, mini vans and tractors in New Mexico, Colorado and the greater southwest. Besides a succinct, pithy statement for natural resource management, the maxim references a land ethic that is particularly evidenced in acequia communities. Put simply, acequias are human-constructed hydrological systems that deliver water to agricultural fields. These community-governed irrigation systems are common in southwestern states– particularly northern New Mexico and southern Colorado. However, the English connotation of ‘irrigation ditch” fails to reflect the different levels of meaning associated with these important water channels. A …

Neutrosophic Sets And Systems, Vol. 41, 2021, Florentin Smarandache, Mohamed Abdel-Basset, Said Broumi

Neutrosophic Sets and Systems

No abstract provided.

Molecular Studies On The Interactions Between Biomphalaria Snails And Schistosoma Mansoni, Lijun Lu

Biology ETDs

Biomphalaria snails serve as vectors for Schistosoma mansoni, a trematode causing human schistosomiasis. Control of Schistosoma mansoni involves chemotherapy of affected people, but new control methods built on improved understanding of schistosome-snail interactions are needed. My dissertation applies molecular and bioinformatics approaches to understand such interactions. Chapter 1 shows that significant differences exist among Biomphalaria species in Africa with respect to their ability to support schistosome development. Chapters 2 and 3 reveal the transcriptional responses of Biomphalaria glabrata susceptible (SUS) or resistant (RES) to Schistosoma mansoni. Chapter 2 identifies a new family of snail immune factors, the AIG …

Aamodt Litigation Settlement Completion, United States 116th Congress

Native American Water Rights Settlement Project

Amends the Aamodt Litigation Settlement Act (Pub. L. 11-291) to increase funding for Pueblo Water Facilities from $106.4 million to $243.4 million and making available $137 million for Regional Water System funding.

Navajo-Utah Water Rights Settlement Act, United States 116th Congress

Native American Water Rights Settlement Project

The purposes of this section are: (1) to achieve a fair, equitable, and final settlement of all claims to water rights in the State of Utah for (A) the Navajo Nation and (B) the United States, for the benefit of the Nation; (2) to authorize, ratify, and confirm the agreement entered into by the Nation and the State, to the extent that the agreement is consistent with this section; (3) to authorize and direct the Secretary (A) to execute the agreement and (B) to take any actions necessary to carry out the agreement in accordance with this section; and (4) …

Montana Water Rights Protection Act, United States 116th Congress

Native American Water Rights Settlement Project

The purposes of this Act are: (1) to achieve a fair, equitable, and final settlement of claims to water rights in the State of Montana, and in recognition of article I, and section 3 of article IX, of the Montana State Constitution for (A) the Confederated Salish and Kootenai Tribes of the Flathead Indian Reservation; and (B) the United States, for the benefit of the Tribes and allottees; (2) to authorize, ratify, and confirm the water rights compact entered into by the Tribes and the State, to the extent that the Compact is consistent with this Act; (3) to authorize …

Visualization Of Real-Time Displacement Time History Superimposed With Dynamic Experiments Using Wireless Smart Sensors And Augmented Reality, Marlon Frank Agüero Injante

Civil Engineering ETDs

Wireless Smart Sensor (WSS) process field data and inform structural field engineers and owners about the infrastructure health, condition, and safety. Engineers acquire the data and investigate changes on displacements under loads to make informed choices and prioritize decisions concerning maintenance, required repairs, and infrastructure replacements. However, reliable data collection and access to displacement information in the field in real-time under loads remains a challenge. The displacement data provided by the WSS in the field undergoes additional processing, and it is seen at a different location, at the decision-making headquarters. If inspectors were able to observe structural displacements in real-time …

Wagon Tracks Volume 35, Issue 1 (November 2020), Santa Fe Trail Association

Wagon Tracks

Contents

2 On the Cover: Sending Them Off: Kit Carson and the Utes: 1843. by Ron Kil

4 Insights from your President

5 Joanne’s Jottings

7 Trail News, Education and Jr. Wagon Master

8 2021 Symposium by Dr. Michael L. Olsen and Harry C. Myers

13 SFTA Awards and Hall of Fame

16 The Diary of Pedro Ignacio Gallego: Meeting Becknell

25 Preservation Efforts on the Santa Fe Trail by Jere L. Krakow

10 The Story behind the Painting, continued

11 Historical Painting: Taking Your Best Shot by Ruth Friesen

31 Book Review: Lifelines: The Bowen Love Letters, compiled …

Effects Of Chronic Stress On Anxiety-Like Behavior And Fear Learning In The Tgf344-Ad Rat Model Of Alzheimer’S Disease, Samuel James Bouquin

Psychology ETDs

Alzheimer’s disease (AD) is a progressive neurodegenerative brain disorder that leads to severe cognitive and functional impairments. Many AD patients also exhibit neuropsychiatric symptoms (NPS) such as anxiety and prior to the clinical diagnosis of dementia. The prodromal manifestation of NPS is highly prevalent among patients with mild cognitive impairment (MCI), and the co-occurrence of preclinical NPS and MCI is associated with an increased risk of developing AD. Prolonged or repeated exposure to stress can result in behavioral disturbances (e.g., anxiety) and accelerated global cognitive decline. Importantly, AD patients exhibit altered stress systems and AD-related neuropathology has been linked to …

Sybil Defense Using Efficient Resource Burning, Diksha Gupta

Computer Science ETDs

In 1993, Dwork and Naor proposed using computational puzzles, a resource burning mechanism, to combat spam email. In the ensuing three decades, resource burning has broadened to include communication capacity, computer memory, and human effort. It has become a well-established tool in distributed security. Due to the cost attached to utilizing resource burning mechanism, these have not been popularized in domains apart from cryptocurrency.

In this dissertation, we design efficient resource burning based Sybil defense techniques for permissionless systems. As a first step, we identify existing resource burning mechanisms in literature in Chapter 2. Additionally, we enumerate numerous open problems …

Prenatal Alcohol Exposure Alters Transcriptional Expression Of Stress And Tlr4-Related Immune Signaling Factors In The Brain Following Early Life Stress, Chaselyn D. Ruffaner-Hanson

Biomedical Sciences ETDs

Background: Depression and anxiety disorders, believed to be caused by stress-related neuropeptides and pro-inflammatory molecules in the brain, are prevalent comorbidities of fetal alcohol spectrum disorders (FASD).

Methods: Brain tissue was collected following a 4-hour maternal separation stress during the early postnatal period, postnatal days 10 and 12, from mice subjected to 1^st and 2^nd trimester prenatal alcohol exposure (PAE).

Hypothesis: We hypothesized that PAE leads to glucocorticoid receptor insensitivity, stress molecule overexpression, and potentiated toll-like receptor 4 (TLR4) pathway inflammatory responses in the brain following early life stress.

Results: PAE and stress increased mRNA expression of TLR4 …

Adult Hippocampal Neurogenesis As A Potential Therapeutic Target In Fetal Alcohol Spectrum Disorders, Kymberly Cheyanne Gustus

Biomedical Sciences ETDs

This dissertation aims to determine if adult hippocampal neurogenesis is a potential therapeutic target in Fetal Alcohol Spectrum Disorders (FASDs). Adult hippocampal neurogenesis plays important and unique roles in certain aspects of learning, memory, and mood (Anacker & Hen, 2017). Individuals with FASDs often demonstrate dysregulation in these arenas (Lewis et al., 2015; Temple, Cook, Unsworth, Rajani, & Mela, 2019). Previous work in our lab using a mouse model of prenatal alcohol exposure demonstrated impairment in enrichment-mediated adult hippocampal neurogenesis (Irene Y. Choi, Andrea M. Allan, & Lee Anna Cunningham, 2005; K. Kajimoto, A. Allan, & L. A. Cunningham, 2013). …

Role Of The Acid Sensing Ion Channel 1a In The Systemic Circulation, Selina M. Garcia

Biomedical Sciences ETDs

Acid-sensing ion channel 1a (ASIC1a) is a non-selective cation channel that is expressed in vascular smooth muscle cells. However, little is known about the contribution of ASIC1a to vascular reactivity and cardiovascular homeostasis. We have previously shown that ASIC1a contributes to pulmonary vascular smooth muscle cell (VSMC) Ca²⁺ entry and vasoconstriction as well as chronic hypoxia-induced pulmonary hypertension. However, a role of ASIC1a in the systemic circulation is unclear. Previous reports have shown that ASIC1a is expressed in femoral and cerebral arteries, however, these studies suggest that ASIC1a contributes to vascular reactivity through neuronal regulation rather than vascular. Therefore, …

The Role Of Anti-Inflammatory Cytokine Interleukin-10 (Il-10) In Tauopathies, Lea L. Weston

Biomedical Sciences ETDs

Tauopathies are neurodegenerative diseases, including Alzheimer’s disease, that are associated with pathological accumulation of the microtubule associated protein tau (MAPT, or tau) (Lee et al., 2001). Abnormal hyperphosphorylated tau (pTau) strongly correlate with cognitive impairment (Nelson et al., 2012). Neuroinflammation is also associated with tauopathies (Gerhard et al., 2006b; Edison et al., 2008) and is implicated in driving tau pathology (Yoshiyama et al., 2007, Maphis et al., 2015b). Therefore, it is compelling to understand the role of anti-inflammatory cytokines in limiting neuroinflammation and tau pathology. Interleukin-10 (IL-10) is a well-established anti-inflammatory cytokine with roles in limiting inflammation in the central …

Virtual And In Vitro Antiviral Screening Revive Therapeutic Drugs For Covid-19, Giovanni Bocci, Steven B. Bradfute, Chunyan Ye, Matthew J. Garcia, Jyothi Parvathareddy, Walter Reichard, Surekha Surendranathan, Shruti Bansal, Cristian G. Bologa, Douglas J. Perkins, Colleen B. Jonsson, Tudor I. Oprea, Larry A. Sklar

Pathology Research and Scholarship

The urgent need for a cure for early phase COVID-19 infected patients critically underlines drug repositioning strategies able to efficiently identify new and reliable treatments by merging computational, experimental, and pharmacokinetic expertise. Here we report new potential therapeutics for COVID-19 identified with a combined virtual and experimental screening strategy and selected among already approved drugs. We used hydroxychloroquine (HCQ), one of the most studied drugs in current clinical trials, as a reference template to screen for structural similarity against a library of almost 4000 approved drugs. The top-ranked drugs, based on structural similarity to HCQ, were selected for in vitro …

Impact Of Cd82 Expression On Acute Myeloid Leukemia Chemosensitivity And Quiescence, Muskan Floren

Biomedical Sciences ETDs

Acute Myeloid Leukemia (AML) patients respond favorably to induction chemotherapy, however, long-term outcomes remain poor due to a high rate of chemoresistance and bone marrow minimal residual disease. To improve long-term patient outcomes, it’s critical to identify regulators of chemotherapy resistance in AML and develop therapies that are directed towards bone marrow resident AML cells. In Chapter 2, we uncover the impact of CD82 expression in AML response to chemotherapeutic treatment and the contribution of Protein Kinase C α (PKCα) and β1 integrin signaling in promoting p38 MAPK activation to support CD82-mediated AML cell survival. In Chapter 3, we …

Farmers’ Place-Based Discourse About Water Relations: Ways Of Knowing Water And Multispecies Survival, Jeffrey Alan Hoffmann

Communication ETDs

The present study looks at farmers’ discourse about water and water relations. Through qualitative interviews using the method of cultural discourse analysis (CuDA), and the framework of ecocultural dialectics, the study reveals how, as farmers talk about water, they also make explicit and implicit arguments about specific cultural relations with the biosphere, as well as the role of identity, place, and power in designing and implementing agricultural solutions to ecological and social problems. I argue that the contradictions in how farmers discursively envision the problems of water pollution and scarcity, as well as solutions to those problems in their farming …

Theoretical And Experimental Studies Of The Emission Of Electromagnetic Radiation By Superluminal Polarization Currents, Andrea Caroline Schmidt-Zweifel

Electrical and Computer Engineering ETDs

Maxwell’s equations establish that patterns of electric charges and currents can be animated to travel faster than the speed of light in vacuo, c, and that these superluminal distribution patterns emit tightly focused packets of electromagnetic radiation that are fundamentally different from the emissions by previously known sources -- on Earth and in the Universe. This dissertation introduces a practical faster-than-light emitter: The superluminal polarization current antenna. Such devices use a polarization current that travels faster than c to give rise to electromagnetic radiation, a technique known as the vacuum Čerenkov effect. In what is to follow, the theoretical and …

The Effects Of Glycosylation On Immunogenicity And Replication Of Emerging Viral Pathogens, Elizabeth Carvosso Clarke

Biomedical Sciences ETDs

For filoviruses, a family of hemorrhagic fever viruses, the main antigen for vaccines in development is the glycosylated glycoprotein GP1,2. How the glycosylation of GP1,2 differs when the protein is produced in different cell lines is unclear. We showed significant differences in the types of glycans conferred onto filovirus GP1,2s in produced in mammalian-origin and insect-origin cell lines. Mammalian-derived filovirus GP1,2s have diverse N-linked glycans and extensive O-linked glycans, whereas insect-derived filovirus GP1,2s have N-linked glycans that are primarily paucimannose type and have no observable O-linked glycans. We then showed that differences in glycosylation impacted how immunogenic the proteins were …

Letter To My Daughter, Kristian Contreras

Intersections: Critical Issues in Education

n/a

Wordhood Issues: Typology And Grammaticalization, Tim Zingler

Linguistics ETDs

This work investigates the distribution of “wordhood issues,” in which a morpheme behaves like a word on one subset of wordhood parameters but like a bound item on another. The empirical focus is on the exponents of definiteness, case, indexation, and tense in 60 unrelated languages from five macro-areas. The methodological basis for the wordhood analyses is a set of eight parameters of phonological and morphological wordhood.

The main result is that grammatical markers (“grams”) retain the ability of morphological words to co-occur with members of different syntactic categories even after being integrated into larger phonological word domains. Meanwhile, grams …

New Mexico: Land Of The Drought, Brandi Davis

Climate Change and Public Health Preparedness

No abstract provided.

Chemical Interfacial Reactions Affecting The Speciation And Solubility Of Uranium In Organic-Rich Environments, Carmen A. Velasco

Civil Engineering ETDs

The aim of this dissertation was to investigate the interfacial reactions between uranium (U) and natural organic matter NOM) affecting the solubility, adsorption, and precipitation of U in organic-rich environments. The chemical interactions between U and NOM are not well understood, which justified the following research objectives: 1) Identify the effect of pH on U speciation and the organic functional chemistry in mineralized deposits from the Jackpile Mine.; 2) Identify the precipitation of U(VI) and NOM as a function of pH (2, 4 and 7); 3) Identify changes in DOM chemistry due to the reaction of NOM and U at …

Online Assessment Methods For Student-Centered Learning: Active Learning, Collaboration, And Application With Authentic Assessment, Charlotte Nirmalani Gunawardena, Stephanie L. Moore Phd, Linda Barril, Kathiravelu Thabotharan

University Libraries & Learning Sciences Faculty and Staff Publications

Agenda

Introduction
Lani Gunawardena

A Learning and Pedagogical Foundation & Taxonomy for Selecting Assessment Methods
Stephanie Moore

Assessing Collaborative Learning
Lani Gunawardena

Student-Centered Assessment Methodologies at the University of Jaffna
K. Thabotharan

Technologies for Assessment
Linda Barril

Labs & Art Online - Assessing Practicals
Stephanie Moore

Questions & Discussion

Radial Basis Densities And The Density Functional-Based Atom-In-Molecule: Designing Charge-Transfer Potentials, Godwin Amo-Kwao

Nanoscience and Microsystems ETDs

Classical potentials that are capable of describing charge transfer and charge polarization in complex systems are of central importance for classical atomistic simulation of biomolecules and materials. Current potentials—regardless of the system—do not generalize well, and, with the exception of highly-specialized empirical potentials tuned for specific systems, cannot describe chemical bond formation and breaking. The charge-transfer embedded atom method (CT-EAM), a formal, DFT-based extension to the original EAM for metals, has been developed to address these issues by modeling charge distortion and charge transfer in interacting systems using pseudoatom building blocks instead of the electron densities of isolated atoms. CT-EAM …

Evolution Of Brain-Wide Activity In The Awake Behaving Mouse After Acute Fear By Longitudinal Manganese-Enhanced Mri, Taylor W. Uselman, Daniel R. Barto, Russell E. Jacobs, Elaine L. Bearer

Pathology Research and Scholarship

Life threatening fear after a single exposure evolves in a subset of vulnerable individuals to anxiety, which may persist for their lifetime. Yet neither the whole brain's response to innate acute fear nor how brain activity evolves over time is known. Sustained neuronal activity may be a factor in the development of a persistent fear response. We couple two experimental protocols to provoke acute fear leading to prolonged fear: Predator stress (PS), a naturalistic approach to induce fear in rodents; and Serotonin transporter knockout mouse (SERT-KO) that responds to PS with sustained defensive behavior. Behavior was monitored before, during and …

Chad: Human Fertility, Crop Production And Changing Weather Patterns, Jake Organ

Economics ETDs

The subject of this dissertation is the effect of changing weather patterns on human fertility in Chad, Sahelian Africa. There is a body of literature on the effect of extreme weather events-usually associated with large-scale mortality-and human fertility. However, there is less of a body of literature on the effects of less extreme changing weather patterns and human fertility. Chad has known substantial warming since the late 1960s, hence I use rising heat as a proxy for changing weather patterns. Using GIS-coded fertility and weather data, I look for correlations between the birth rate and the number of days in …

A Bayesian Network Analysis Of The Human Exposure To Escherichia Coli Bacteria In The Environment, Brandon G. De Flon

Mathematics & Statistics ETDs

Diarrhea is a leading cause of death worldwide because a lack thereof in household sanitization exposes humans to high concentrations of pathogenic Escherichia coli. In 2016, the University of New Mexico’s Nepal Study Center collected cross-sectional survey data using proportional random sampling on three communities in Western Nepal. Structural and parameter learning estimation and approximate inference of Bayesian networks studied diarrheagenic E. coli exposure while incorporating participation in sanitary behaviors, access to sanitary built-in environments, and other human characteristics. Of the reported sickness, hand washing resulted in a 20 percent decrease, water treatment 8 percent, and both 28 percent. Of …

The Combined Effects Of Exercise-Induced Muscle Damage And Heat Stress On Acute Kidney Stress And Heat Strain During Subsequent Endurance Exercise, Zidong Li

Health, Exercise, and Sports Sciences ETDs

Purpose: The purpose of this study was to investigate the combined effect of downhill running and heat stress on muscle damage, as well as on heat strain and kidney stress during subsequent endurance exercise in the heat. Methods: Using a crossover design and randomized order, ten non-heat-acclimated, physically active males completed downhill running in a cool (EIMD in Cool) and hot (EIMD in Hot) environment followed by an exercise-heat stress (HS) test after 3-hour seated rest. Core temperature, heart rate, thermal sensation and ratings of perceived exertion were recorded throughout each exercise session. Blood and urine samples were collected at …

Inoculum Potential Of Pinus Edulis-Associated Ectomycorrhizal Fungi Across A Forest Extirpation Chronosequence, Annie M. Montes

Biology ETDs

Few studies have examined inoculum potential of ectomycorrhizal fungi (EMF) in the absence of plant hosts, yet persistence of these fungi may be paramount to resilience of Pinus edulis and other mycorrhizal plant species. We conducted a study in which seven sites were selected in northwestern New Mexico with known dates of P. edulis extirpation and a lack of regeneration. Age classes included: two sites extirpated 10-20 years ago, two extirpated 55-65 years ago, two extirpated 500+ years ago, and one extirpated 11,000+ years ago. At each site, two plots were paired: an extirpated plot and the nearest live adult …