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Competency-Based Personnel Selection Oklahoma - Final Summary, Quality Improvement Center For Workforce Development Nov 2023

Competency-Based Personnel Selection Oklahoma - Final Summary, Quality Improvement Center For Workforce Development

Other QIC-WD Products

Oklahoma Department of Human Services (OKDHS) is a state-operated child welfare system, but hiring has always been done locally. The agency is divided into five field regions serving 27 districts and 77 counties. In 2017, OKDHS employed 1,780 Child Welfare Specialists (caseworkers) and 388 supervisors. That same year, the annual turnover rate was 25%. They applied to be a QIC-WD site with the goal of strengthening their child welfare workforce.

When OKDHS started working with the Quality Improvement Center for Workforce Development (QIC-WD), a steering committee was established to participate in a needs assessment process, determine an intervention, and support …


Janus , A Spliceosome-Associated Protein, Promotes Mirna Biogenesis In Arabidopsis, Mu Li, Huihui Yu, Bangjun Zhou, Lu Gan, Shengjun Li, Chi Zhang, Bin Yu Nov 2023

Janus , A Spliceosome-Associated Protein, Promotes Mirna Biogenesis In Arabidopsis, Mu Li, Huihui Yu, Bangjun Zhou, Lu Gan, Shengjun Li, Chi Zhang, Bin Yu

Center for Plant Science Innovation: Faculty Publications

MicroRNAs ( miRNAs ) are important regulators of genes expression. Their levels are precisely controlled through modulating the activity of the microprocesser complex ( MC ) . Here, we report that JANUS, a homology of the conserved U2 snRNP assembly factor in yeast and human, is required for miRNA accumulation. JANUS associates with MC components Dicer-like 1 ( DCL1 ) and SERRATE ( SE ) and directly binds the stem- loop of pri-miRNAs. In a hypomorphic janus mutant, the activity of DCL1, the numbers of MC, and the interaction of primary miRNA transcript ( pri-miRNAs ) with MC are reduced. …


Value Added By Using Joint Displays In Mixed Methods Research, Elizabeth Svoboda Nov 2023

Value Added By Using Joint Displays In Mixed Methods Research, Elizabeth Svoboda

Dissertations and Doctoral Documents, University of Nebraska-Lincoln, 2023–

Mixed methods research collects, analyzes, and integrates rigorous qualitative and quantitative methods to gain a deeper understanding of a phenomenon than would be gained by using either method alone. Integration is one of the key features of mixed methods research and consists of mixing qualitative and quantitative research in a systematic way to generate new inferences or follow-up studies. However, the process of integration can be challenging to draw on expertise in both qualitative and quantitative methods, decide when and how to integrate qualitative and quantitative research, and combine multiple data sources in a coherent way to generate new inferences. …


Comparative Analysis Of Swine Antibody Responses Following Vaccination With Live-Attenuated And Killed African Swine Fever Virus Vaccines, Hung Q. Luong, Huong T. L. Lai, Lam Q. Truong, The N. Nguyen, Hanh D. Vu, Hoa T. Nguyen, Lan T. Nguyen, Trang H. Pham, David Scott Mcvey, Hiep Vu Nov 2023

Comparative Analysis Of Swine Antibody Responses Following Vaccination With Live-Attenuated And Killed African Swine Fever Virus Vaccines, Hung Q. Luong, Huong T. L. Lai, Lam Q. Truong, The N. Nguyen, Hanh D. Vu, Hoa T. Nguyen, Lan T. Nguyen, Trang H. Pham, David Scott Mcvey, Hiep Vu

Nebraska Center for Virology: Faculty Publications

African swine fever virus (ASFV) is circulating in many swine-producing countries, causing significant economic losses. It is observed that pigs experimentally vaccinated with a live-attenuated virus (LAV) but not a killed virus (KV) vaccine develop solid homologous protective immunity. The objective of this study was to comparatively analyze antibody profiles between pigs vaccinated with an LAV vaccine and those vaccinated with a KV vaccine to identify potential markers of vaccineinduced protection. Thirty ASFV seronegative pigs were divided into three groups: Group 1 received a single dose of an experimental LAV, Group 2 received two doses of an experimental KV vaccine, …


Reduced Grey Matter Volume In Adolescents With Conduct Disorder: A Region‑Of‑Interest Analysis Using Multivariate Generalized Linear Modeling, Ru Zhang, Robert James R. Blair, Karina S. Blair, Matthew Dobbertin, Jaimie Elowsky, Johannah Bashford‑Largo, Ahria J. Dominguez, Melissa Hatch, Sahil Bajaj Nov 2023

Reduced Grey Matter Volume In Adolescents With Conduct Disorder: A Region‑Of‑Interest Analysis Using Multivariate Generalized Linear Modeling, Ru Zhang, Robert James R. Blair, Karina S. Blair, Matthew Dobbertin, Jaimie Elowsky, Johannah Bashford‑Largo, Ahria J. Dominguez, Melissa Hatch, Sahil Bajaj

Center for Brain, Biology, and Behavior: Faculty Publications

Background

Conduct disorder (CD) involves a group of behavioral and emotional problems that usually begins during childhood or adolescence. Structural brain alterations have been observed in CD, including the amygdala, insula, ventrolateral and medial prefrontal cortex, anterior cingulate cortex, and fusiform gyrus. The current study developed a multivariate generalized linear model (GLM) to differentiate adolescents with CD from typically developing (TD) adolescents in terms of grey matter volume (GMV).

Methods

The whole‐brain structural MRI data were collected from 96 adolescents with CD (mean age = 16.188 ± 1.259 years; mean IQ = 104.292 ± 8.107 ; 63 males) and 90 …


A Multi-Organ Maize Metabolic Model Connects Temperature Stress With Energy Production And Reducing Power Generation, Niaz Bahar Chowdhury, Margaret Simons- Senftle, Berengere Decouard, Isabelle Quillere, Martine Rigault, Karuna Anna Sajeevan, Bibek Acharya, Ratul Chowdhury, Bertrand Hirel, Alia Dellagi, Costas Maranas, Rajib Saha Nov 2023

A Multi-Organ Maize Metabolic Model Connects Temperature Stress With Energy Production And Reducing Power Generation, Niaz Bahar Chowdhury, Margaret Simons- Senftle, Berengere Decouard, Isabelle Quillere, Martine Rigault, Karuna Anna Sajeevan, Bibek Acharya, Ratul Chowdhury, Bertrand Hirel, Alia Dellagi, Costas Maranas, Rajib Saha

Department of Chemical and Biomolecular Engineering: Faculty Publications

Climate change has adversely affected maize productivity. Thereby, a holistic understanding of metabolic crosstalk among its organs is important to address this issue. Thus, we reconstructed the first multi-organ maize metabolicmodel, iZMA6517, and contextualized itwith heat and cold stress transcriptomics data using expression distributed reaction flux measurement (EXTREAM) algorithm. Furthermore, implementing metabolic bottleneck analysis on contextualized models revealed differences between these stresses. While both stresses had reducing power bottlenecks, heat stress had additional energy generation bottlenecks.We also performed thermodynamic driving force analysis, revealing thermodynamics-reducing power-energy generation axis dictating the nature of temperature stress responses. Thus, a temperaturetolerant maize ideotype can …


Formal Concept Analysis For Image Classification And Machine Learning Models For Anti-Crispr Protein Discovery In Bioinformatics, Minal Khatri Nov 2023

Formal Concept Analysis For Image Classification And Machine Learning Models For Anti-Crispr Protein Discovery In Bioinformatics, Minal Khatri

Dissertations and Doctoral Documents, University of Nebraska-Lincoln, 2023–

This study investigates two critical areas in bioinformatics: enhancing transparency in medical image analysis and advancing the discovery of Anti-CRISPR (Acr) proteins, which have potential in developing more precise and controlled CRISPR-Cas gene editing tools. While CNN’s are increasingly applied in critical fields like medical diagnosis, understanding their decision-making process remains a challenge. Although visualization techniques like Saliency maps offer insights into CNN’s decision-making for individual images, they do not explicitly establish a relationship between the high-level features learned by CNN’s and the class labels across dataset. To bridge this gap, Formal Concept Analysis (FCA) framework is leveraged as a …


Center For Grassland Studies, November 2023 Nov 2023

Center For Grassland Studies, November 2023

Center for Grassland Studies: Newsletters

Contents

Experiential Learning for Grassland Conservation by David Wedin

Center for Grassland Studies Policy Advisory Committee

Director’s Column by David Wedin

New Woody Invasions Ecologist Brings Additional Capacity for Grassland Conservation by Dillon Fogarty

Twidwell Racks-up awards for his work in Grassland Conservation by Geitner Simmons

Platte Basin Timelapse premieres New Film on Nine-Mile Prairie by David Wedin

CRAWL: Update on the Network for Integrated Agricultural Resilience Research by Craig Allen

CGS Outreach by Jerry Volesky

Center for Grassland Studies Awards 19 Scholarships Totaling $17,500 for 2023-2024 by David Wedin

Award winners:

Joseph O. Young Fund = Makenna Anderson, Makennen …


The Casnr L.I.N.K.S. Newsletter: Learning Innovation Network For K-12 Schools, Volume 2, Edition 10, November 2023, Bailey Feit, Tammy Mittelstet Nov 2023

The Casnr L.I.N.K.S. Newsletter: Learning Innovation Network For K-12 Schools, Volume 2, Edition 10, November 2023, Bailey Feit, Tammy Mittelstet

CASNR L.I.N.K.S. Newsletter

The purpose of this L.I.N.K.S. newsletter is to provide a monthly update of opportunities and resources for K-12 schools to connect with the University of Nebraska's CASNR Food, Energy, Water, and Societal Systems (FEWS²) programs and partners.

Included in this edition:

UNL Institute of Agriculture and Natural Resources, Agricultural Economics, high school commodity market curriculum

UNL CASNR Changemaker competition

UNL Department of Food Science and Technology

Health system innovators spotlight

UNL Department of Biochemistry

UNL Department of Microbiology

Student and teacher opportunities:

Engler Agribusiness, Native American Coalition, Next Black and Hispanic Farmers Scholarship, World Food Prize Youth Institute scholarship, Midwest …


K–12 Teachers Perspectives On Mobile Technology Integration: A Qualitative Study, Steven Justin Bingham Nov 2023

K–12 Teachers Perspectives On Mobile Technology Integration: A Qualitative Study, Steven Justin Bingham

Department of Teaching, Learning, and Teacher Education: Theses and Other Student Research

The purpose of this qualitative case study was to develop an understanding of mobile technology integration in K-12 classrooms from the perspective of classroom teachers during the 2022-2023 school year. The increase in mobile technologies being utilized in schools made it imperative to understand how mobile devices are being integrated into the classroom from the teacher’s perspective. The central research question was, how do teachers at K-12 schools in the Midwest describe their perception and usage of mobile technology integration in teaching and learning?

The data collection consisted of semi-structured interviews with fourteen participants from one school district in the …


Transportation Components Of The City Of Bennet Comprehensive Plan And Downtown Economic Development Plan, Kyle Mclaughlin Nov 2023

Transportation Components Of The City Of Bennet Comprehensive Plan And Downtown Economic Development Plan, Kyle Mclaughlin

Community and Regional Planning Program: Theses

In partnership with the City of Bennet, the University of Nebraska, and Marvin Planning Consultants, this project assisted the creation of the City’s Comprehensive Plan and Downtown Economic Development Plan by creating a transportation focused report as a supplement to those plans. The project operates in six sections; Introduction and Overview, Evaluate the Present, Engage the Community, Recommendations, Strategies, and Policies, Implementation and Funding, and Monitoring and Evaluation. The project scope included existing conditions understanding, qualitative and quantitative transportation analysis, public engagement and stakeholder meetings, coordination with two plan creators, identifying transportation improvements, description of implementation steps, overview of available …


A Memoir Of The Neutzner Family, Hannelore Neutzner Rogers Nov 2023

A Memoir Of The Neutzner Family, Hannelore Neutzner Rogers

Archives & Special Collections

A memoir describing the forced expulsion and resettlement the Neutzner family and their relatives from Czechoslovakia to the German Sudetenland during World War II and their later emigration to the United States.


Continuous Time Recurrent Network For Human Activity Detection, Abdallah Al Zubi Nov 2023

Continuous Time Recurrent Network For Human Activity Detection, Abdallah Al Zubi

Durham School of Architectural Engineering and Construction: Dissertations, Theses, and Student Research

Human activity detection is crucial to personalize the control of the building environment. For example, understanding certain human activities (e.g., walking, sitting, etc.) for an occupant in a building helps provide the proper thermal comfort control. However, these applications require large-scale neural networks that are challenging to implement and train.

In this thesis, we implemented a continuous-time recurrent neural network implementation (CTRNN) network that can solve real-time human activity detection with a smaller-size network. The CTRNN uses differential equations with a time constant to describe the neuron equations. It was implemented and trained for the first time using TensorFlow. Specifically, …


How Peer Mentors Support The Transition Of First-Year College Students, Blair Prevost Nov 2023

How Peer Mentors Support The Transition Of First-Year College Students, Blair Prevost

Dissertations and Doctoral Documents, University of Nebraska-Lincoln, 2023–

This qualitative, multiple case study examined how peer mentors at a public, four-year university supported the transition of first-year college students. Using Schlossberg’s (Anderson et al., 2021) Transition Framework the study was guided by the following questions: 1) How did peer mentors, in light of the Approaching Transitions phase in Schlossberg’s (Anderson et al., 2021) theory, help first-time students understand their college transition? 2) In what ways did peer mentors directly provide support to first-time students to help first-time students as they transition to college? 3) With what other support resources, whether on or off campus, did peer mentors connect …


K-12 Teachers' Perspectives On Mobile Technology Integration: A Qualitative Study, Steven Justin Bingham Nov 2023

K-12 Teachers' Perspectives On Mobile Technology Integration: A Qualitative Study, Steven Justin Bingham

Dissertations and Doctoral Documents, University of Nebraska-Lincoln, 2023–

The purpose of this qualitative case study was to develop an understanding of mobile technology integration in K–12 classrooms from the perspective of classroom teachers during the 2022-2023 school year. The increase in mobile technologies being utilized in schools made it imperative to understand how mobile devices are being integrated into the classroom from the teacher’s perspective. The central research question was, how do teachers at K–12 schools in the Midwest describe their perception and usage of mobile technology integration in teaching and learning? The data collection consisted of semi-structured interviews with fourteen participants from one school district in the …


Collaborative Practices Between General Education Teachers And Teachers Of The Deaf/Hard Of Hearing: A Narrative Inquiry, Kayla Power Nov 2023

Collaborative Practices Between General Education Teachers And Teachers Of The Deaf/Hard Of Hearing: A Narrative Inquiry, Kayla Power

Dissertations and Doctoral Documents, University of Nebraska-Lincoln, 2023–

The US Individuals with Disabilities Education Act (2004) states that students with disabilities should receive instruction in the general education classroom as much as possible. This move has resulted in Deaf/Hard of Hearing (DHH) students spending more of their time in the general education classroom which has increased the need for collaboration between Teachers of the Deaf (TODs) and general education teachers. The purpose of this qualitative study is to examine what collaboration between TODs and general education teachers looks like in an elementary school setting. Data consisted of individual interviews and observations. Using a narrative inquiry approach, I restory …


Characterization Of Adipocyte Mechanical Properties And Stretch Control Of Mechanosignaling In Adipocytes, Tasneem Bouzid Nov 2023

Characterization Of Adipocyte Mechanical Properties And Stretch Control Of Mechanosignaling In Adipocytes, Tasneem Bouzid

Dissertations and Doctoral Documents, University of Nebraska-Lincoln, 2023–

Obesity has reached global epidemic levels in recent decades and is the leading risk factor for type-2 diabetes (T2D). Adipose tissue behaves as a link between obesity and T2D, with dysfunctional extracellular matrix (ECM) remodeling, adipokine secretion and lipid metabolism leading to insulin resistance. The extracellular mechanophysical milieus is understood to regulate adipocyte differentiation and function through activation of mechanosensory machinery and related pathways. Therefore, exploring the adipocytic response to mechanical loading can provide great pathophysiological insight into obesity and T2D.

Adipose tissue is exposed to various compound forces due to weight-bearing and movement, and adipocyte stiffness influences stress distribution …


An Illuminative Evaluation Of Two Models Of Reading Intervention Used In Middle Schools, Tachier M. Rezac Nov 2023

An Illuminative Evaluation Of Two Models Of Reading Intervention Used In Middle Schools, Tachier M. Rezac

Dissertations and Doctoral Documents, University of Nebraska-Lincoln, 2023–

Intervention research often investigates the curriculum or methods used to support learners, while less attention is given to the model of those interventions. The purpose of this study was to evaluate the efficacy of two models of reading intervention, and to better understand how they are serving middle school students. Working from a critical pragmatic lens, I employed illuminative evaluation methods to investigate three research questions: (a) What are the demographic profiles of students enrolled in reading intervention in grades seven and eight; (b) What are the differences in gains for students enrolled in the traditional intervention and reading lab …


The Development And Evolution Of The Soil Health Nutrient Tool (Aka Haney Test) After Ten Years Of Implementation In A Commercial Agricultural Laboratory, Lance Michael Gunderson Nov 2023

The Development And Evolution Of The Soil Health Nutrient Tool (Aka Haney Test) After Ten Years Of Implementation In A Commercial Agricultural Laboratory, Lance Michael Gunderson

Dissertations and Doctoral Documents, University of Nebraska-Lincoln, 2023–

The growing focus on soil health and regenerative agriculture has brought about the need for new integrated approaches for the analysis of soil. Prior, commercial agricultural laboratories relied on methods to measure chemical properties of the soil, such as pH and nutrients. The Soil Health Nutrient Tool (aka Haney Test) developed by Dr. Rick Haney (United States Department of Agriculture, Agricultural Research Service (USDA-ARS), Blackland Research and Extension Station, Temple, Texas) integrates chemical and biological properties to provide a more holistic understanding of soil fertility management. Following adoption by commercial laboratories in 2013, criticisms regarding variability in measurements and lack …


Precipitation And Greenness In Pastoral Lands Of East Turkana, Kenya, Paul Akpejeluh Nov 2023

Precipitation And Greenness In Pastoral Lands Of East Turkana, Kenya, Paul Akpejeluh

School of Natural Resources: Dissertations, Theses, and Student Research

Pastoralism has long supported livelihoods and provided essential ecosystem services in landscapes of East Africa. Vegetation productivity is central to the functioning of pastoral systems but may be affected by changes in climate and landuse. Vegetation monitoring is important for understanding the effects of global change in pastoral lands; however, it can be time and resource intensive. Remote sensing provides opportunities for efficient multi-scale monitoring of vegetation and climatic drivers. In this thesis, I explore the utility of satellite and UAV remote sensing for monitoring vegetation and precipitation trends and relationships in the East of Lake Turkana Region of northern …


Connecting The Nebraska Water Quality Index To The Aquatic Microbial Community Of The North Platte River Basin, Nebraska, Paula R. Guastello Nov 2023

Connecting The Nebraska Water Quality Index To The Aquatic Microbial Community Of The North Platte River Basin, Nebraska, Paula R. Guastello

School of Natural Resources: Dissertations, Theses, and Student Research

The Nebraska Water Quality Index, under development by the Nebraska Department of Environment and Energy, summarizes in a single value eight environmental parameters that have been monitored in Nebraska for nearly 20 years. Water quality parameters including those used in the Nebraska Water Quality Index have been shown in previous studies to impact bacterial growth. As such, this index has the potential to correlate with the freshwater microbial community. Here, I relate the Nebraska Water Quality Index to microbial community composition and structure using 16S rRNA gene amplicon sequence data collected from the North Platte River Basin, Nebraska. This index …


Housing Discrimination And Negative Attitudes Towards Ex-Offender Parents, Julie Wertheimer-Meier Nov 2023

Housing Discrimination And Negative Attitudes Towards Ex-Offender Parents, Julie Wertheimer-Meier

Department of Psychology: Dissertations, Theses, and Student Research

While the Fair Housing Act prohibits housing discrimination because of race, gender, religion, sex, disability, family status, and national origin, it allows housing providers to discriminate on the basis of criminal history. Prior research shows that housing providers disproportionately deny housing to ex-offender applicants and single parent applicants with young children. An ex-offender parent’s inability to acquire safe and affordable housing decreases the potential for reunification with their children and increases the risk of lost custody or parental rights termination. This dissertation consisted of two experiments that examined the effects of negative attitudes towards ex-offender parents on those parents’ ability …


Discursive Struggles Reflected In The Communication Of Conservative Christian Parents And Their Adult Children With Differing Religious Beliefs And Values, Braedon G. Worman Nov 2023

Discursive Struggles Reflected In The Communication Of Conservative Christian Parents And Their Adult Children With Differing Religious Beliefs And Values, Braedon G. Worman

Department of Communication Studies: Dissertations, Theses, and Student Research

Nearly half of American adults no longer believe in their childhood faiths (Pew Research Center, 2015). The steady decline of Christianity could have considerable impacts on family life (Pew Research Center, 2022). From a postmodern critical perspective and guided by Relational Dialectics Theory 2.0, the researcher sought to discern how conservative Christian parents and their adult children with differing religious beliefs and values communicated when they discussed these differences, as well as to identify the discourses that informed and were reflected in their talk and illustrate how these discourses interplayed and animated the meaning of participants’ Christian family identities. The …


Off The Rails: Cinematic Trains As Technological Controls Of The Natural World, Trinity Thompson Nov 2023

Off The Rails: Cinematic Trains As Technological Controls Of The Natural World, Trinity Thompson

Honors Program: Senior Projects (Public)

Short train rail lines across the United States are seeing increased national funding to reduce toxic chemical spills caused by train derailments, the most notable of which happened in February 2023 in East Palestine, Ohio. A year prior, the film White Noise (2022) featured a similar toxic train derailment incident, taking place, too, in Eastern Ohio, and featuring actors from the town of East Palestine. In considering other films featuring trains, I identified a pattern of environmental conflict, leading me to question the relationship between trains and the natural environment as portrayed in popular cinema. To conduct my research, I …


Classifying Diseases Affecting Gait With Body Acceleration-Based Machine Learning Models, Mohammad Ali Takallou Nov 2023

Classifying Diseases Affecting Gait With Body Acceleration-Based Machine Learning Models, Mohammad Ali Takallou

Dissertations and Doctoral Documents, University of Nebraska-Lincoln, 2023–

This Ph.D. dissertation introduces a comprehensive framework designed to harness acceleration data as a uniquely valuable tool for early disease classification, specifically focusing on gait-related diseases. In the modern healthcare landscape, timely and accurate classification of such diseases is paramount, as it can significantly impact treatment outcomes and patient quality of life.

As a compelling case study, we conducted a meticulous experiment to identify individuals afflicted with peripheral artery disease (PAD) and classify them from those without PAD. Our framework leverages acceleration data extracted from strategically placed anatomical reflective markers, including locations such as the sacrum, to train sophisticated classification …


Tame The Flame: Inflammation Is A Targetable Physiological Mechanism Underlying Poor Outcomes Of Heat Stress In Finishing Sheep, Pablo C. Grijalva Nov 2023

Tame The Flame: Inflammation Is A Targetable Physiological Mechanism Underlying Poor Outcomes Of Heat Stress In Finishing Sheep, Pablo C. Grijalva

Dissertations and Doctoral Documents, University of Nebraska-Lincoln, 2023–

This research focused on health management through the identification of suitable interventions in stressed livestock. For this investigation, we conducted two experiments. First, we determined whether administration of dexamethasone or fish oil to heat-stressed livestock to reduce systemic inflammation would mitigate metabolic deficits, enhance nutrient utilization, and improve health. We found that these interventions helped to reduce circulating inflammatory cytokines and improve respiration, muscle glucose metabolism, lipid homeostasis, cardiovascular function, and organ pathology in lambs exposed to 30 days of heat stress. In our second experiment, we performed transcriptomic analyses to identify the underlying mechanisms affecting young offspring following prenatal …


Characterization And Evaluation Of Bioactivity Of Dry Edible Bean And Bean Derived Small Peptides, Bikram Prasad Upadhyaya Nov 2023

Characterization And Evaluation Of Bioactivity Of Dry Edible Bean And Bean Derived Small Peptides, Bikram Prasad Upadhyaya

Dissertations and Doctoral Documents, University of Nebraska-Lincoln, 2023–

Obesity, diabetes, and their metabolic complications continue to be one of the major global public health concerns with a few effective treatment options. Although regular exercise and a well-balanced diet that includes calories from pulses can be recommended, much remains to be elucidated about the health effects of the various bioactive compounds including peptides and polyphenols present in pulses. Most of the previous studies have focused on individual dietary compounds and only a few investigated the synergistic effect of active compounds in modulating human health. Hence this dissertation aimed first, to provide a comparative evaluation of the overall therapeutic value …


Biomimetic Approach To Elucidate The Role Of Microenvironment In Regulating Cell Communications In Liver Diseases, Youra Moeun Nov 2023

Biomimetic Approach To Elucidate The Role Of Microenvironment In Regulating Cell Communications In Liver Diseases, Youra Moeun

Dissertations and Doctoral Documents, University of Nebraska-Lincoln, 2023–

Liver is a complex organ but often underappreciated for its functions to remove toxins and fight infection in the body. Despite the ongoing prevalence of patients contracting chronic liver diseases, coupled with a global healthcare investment of approximately $70 billion, there is still no effective treatment for chronic liver diseases including alcoholic liver disease. The purpose of this dissertation was to understand the interactions of parenchymal and non-parenchymal liver cells in physiological and pathological like environments. This allowed us to recreate a healthy and the diseased microenvironments to observe the stages of the liver diseases development and apply appropriate treatments …


Housing Discrimination And Negative Attitudes Towards Ex-Offender Parents, Julie C. Wertheimer-Meier Nov 2023

Housing Discrimination And Negative Attitudes Towards Ex-Offender Parents, Julie C. Wertheimer-Meier

Dissertations and Doctoral Documents, University of Nebraska-Lincoln, 2023–

While the Fair Housing Act prohibits housing discrimination because of race, gender, religion, sex, disability, family status, and national origin, it allows housing providers to discriminate on the basis of criminal history. Prior research shows that housing providers disproportionately deny housing to ex-offender applicants and single parent applicants with young children. An ex-offender parent’s inability to acquire safe and affordable housing decreases the potential for reunification with their children and increases the risk of lost custody or parental rights termination. This dissertation consisted of two experiments that examined the effects of negative attitudes towards ex-offender parents on those parents’ ability …


Gene Variants In Bola-Dmb, Decr1, Fasn And Srebf1 Associated With Conceptus Death On Day 16 Of Pregnancy In Holstein Cows [Abstract], Carolina L. Gonzalez-Berrios, Courtney Bowden, Pablo J. Pinedo, Jeanette V. Bishop, Hana Van Campen, Thomas R. R. Hansen, Milton G. Thomas Nov 2023

Gene Variants In Bola-Dmb, Decr1, Fasn And Srebf1 Associated With Conceptus Death On Day 16 Of Pregnancy In Holstein Cows [Abstract], Carolina L. Gonzalez-Berrios, Courtney Bowden, Pablo J. Pinedo, Jeanette V. Bishop, Hana Van Campen, Thomas R. R. Hansen, Milton G. Thomas

United States Department of Agriculture Wildlife Services: Staff Publications

Investigating the influences of single nucleotide polymorphisms (SNP) associated with conceptus death (CD) on day 16 of pregnancy could distinguish cows who have inferior value for fertility traits. We hypothesized that CD is associated with SNP genotypes that disrupt maternal recognition and lead to early pregnancy loss. RNA sequences from Holstein cow pregnancies (n = 15) with normal conceptuses (Norm) or CD were subjected to SNP discovery via Qiagen CLC Genomics Workbench. Selected SNP were based on previous fertility studies, differentially expressed genes within pregnancy development analyses and proximity to SNP associated with fertility traits in the Cattle QTL …