Open Access. Powered by Scholars. Published by Universities.®

Digital Commons Network™

Open Access. Powered by Scholars. Published by Universities.®

University of Nebraska - Lincoln

Discipline
Keyword
Publication Year
Publication
Publication Type
File Type

Articles 6541 - 6570 of 38030

Full-Text Articles in Entire DC Network

A Comparative Analysis Of Motifs From Minoan And Hungarian Folk Art, Peter Z. Revesz Jan 2018

A Comparative Analysis Of Motifs From Minoan And Hungarian Folk Art, Peter Z. Revesz

School of Computing: Faculty Publications

This paper presents a similarity measure for motives. The similarity measure is applied to several ceramic and metal artifacts that contain spiral motives. The similarity measure shows a particularly strong similarity between some Minoan and Hungarian ceramics.


The Long Term Effect Of Agricultural, Vadose Zone And Climatic Factors On Nitrate Contamination In Nebraska’S Groundwater System, Pongpun Juntakut, Daniel D. Snow, Erin M.K. Haacker, Chittaranjan Ray Jan 2018

The Long Term Effect Of Agricultural, Vadose Zone And Climatic Factors On Nitrate Contamination In Nebraska’S Groundwater System, Pongpun Juntakut, Daniel D. Snow, Erin M.K. Haacker, Chittaranjan Ray

Nebraska Water Center: Faculty Publications

A four-decade dataset (1974–2013) of 107,823 nitrate samples in 25,993 wells from western and eastern parts of Nebraska was used to assess long-term trends of groundwater nitrate concentration and decadal changes in the extent of groundwater nitrate-contaminated areas (NO3-N≥10 mg N/L) over the entire state. Spatial statistics and regressions were used to investigate the relationships between groundwater nitrate concentrations and several potential natural and anthropogenic factors, including soil drainage capacities, vadose zone characteristics, crop production areas, and irrigation systems. The results of this study show that there is no statistically significant trend in groundwater nitrate concentrations …


A Scalable And Efficient Bioprocess For Manufacturing Human Pluripotent Stem Cell-Derived Endothelial Cells, Haishuang Lin, Qian Du, Qiang Li, Ou Wang, Zhanqi Wang, Neety Sahu, Christian Elowsky, Kan Liu, Chi Zhang, Soonkyu Chung, Bin Duan, Yuguo Lei Jan 2018

A Scalable And Efficient Bioprocess For Manufacturing Human Pluripotent Stem Cell-Derived Endothelial Cells, Haishuang Lin, Qian Du, Qiang Li, Ou Wang, Zhanqi Wang, Neety Sahu, Christian Elowsky, Kan Liu, Chi Zhang, Soonkyu Chung, Bin Duan, Yuguo Lei

Department of Chemical and Biomolecular Engineering: Faculty Publications

Endothelial cells (ECs) are of great value for cell therapy, tissue engineering, and drug discovery. Obtaining high-quantity and -quality ECs remains very challenging. Here, we report a method for the scalable manufacturing of ECs from human pluripotent stem cells (hPSCs). hPSCs are expanded and differentiated into ECs in a 3D thermoreversible PNIPAAm-PEG hydrogel. The hydrogel protects cells from hydrodynamic stresses in the culture vessel and prevents cells from excessive agglomeration, leading to high-culture efficiency including high-viability (>90%), high-purity (>80%), and high-volumetric yield (2.0 x 107 cells/mL). These ECs (i.e., 3D-ECs) had similar properties as ECs made using …


A Preliminary Study Of The Influence Of Breeding Area Density On Sandhill Crane Habitat Selection In South-Central Wisconsin, Sara A. Prussing, Hillary L. Thompson Jan 2018

A Preliminary Study Of The Influence Of Breeding Area Density On Sandhill Crane Habitat Selection In South-Central Wisconsin, Sara A. Prussing, Hillary L. Thompson

Proceedings of the North American Crane Workshop

We hypothesized that territorial sandhill cranes (Grus canadensis) in densely populated breeding areas occupy smaller home ranges that are richer in optimal habitat than those in less densely populated breeding areas. We analyzed satellite telemetry data collected from 2012 to 2016 for 3 and 2 sandhill cranes from dense and less dense breeding areas, respectively. Tracked sandhill cranes in a dense breeding area tended to have smaller home ranges (0.37-14.25 km2) with higher concentrations of wetlands (27%) and row crops (40%) than tracked sandhill cranes in the less dense breeding area (8.80-48.81 km2, 14% …


Impacts: Annual Report Fy2018 (July 1, 2017 To June 30, 2018), Robert B. Daugherty Water For Food Global Institute Jan 2018

Impacts: Annual Report Fy2018 (July 1, 2017 To June 30, 2018), Robert B. Daugherty Water For Food Global Institute

Daugherty Water for Food Global Institute: Administrative Materials

One in nine people goes to bed hungry each night, according to the U.N. World Food Program. That’s 795 million people on the planet who do not have access to enough nutritious food. The challenge is growing. Global drivers like climate change, urbanization and increasing demand for water-intensive agricultural products are altering landscapes, increasing soil erosion, and degrading water resources and soils in important food producing regions around the world. We must figure out how to feed a global population projected to reach 10 billion by 2050, with the same amount of water and arable land – and quickly. This …


Visible Light Crosslinkable Human Hair Keratin Hydrogels, Kan Yue, Yanhui Liu, Batzaya Byambaa, Vaishali Singh, Wanjun Liu, Xiuyu Li, Yunxia Sun, Yu Shrike Zhang, Ali Tamayol, Peihua Zhang, Kee Woei Ng, Nasim Annabi, Ali Khademhosseini Jan 2018

Visible Light Crosslinkable Human Hair Keratin Hydrogels, Kan Yue, Yanhui Liu, Batzaya Byambaa, Vaishali Singh, Wanjun Liu, Xiuyu Li, Yunxia Sun, Yu Shrike Zhang, Ali Tamayol, Peihua Zhang, Kee Woei Ng, Nasim Annabi, Ali Khademhosseini

Department of Mechanical and Materials Engineering: Faculty Publications

Keratins extracted from human hair have emerged as a promising biomaterial for various biomedical applications, partly due to their wide availability, low cost, minimal immune response, and the potential to engineer autologous tissue constructs. However, the fabrication of keratin-based scaffolds typically relies on limited crosslinking mechanisms, such as via physical interactions or disulfide bond formation, which are time-consuming and result in relatively poor mechanical strength and stability. Here, we report the preparation of photocrosslinkable keratin-polyethylene glycol (PEG) hydrogels via the thiol-norbornene “click” reaction, which can be formed within one minute upon irradiation of visible light. The resulting keratin-PEG hydrogels showed …


The Honor Society Of Agriculture Gamma Sigma Delta, Nebraska Chapter, History, May 25, 1918-2018 Jan 2018

The Honor Society Of Agriculture Gamma Sigma Delta, Nebraska Chapter, History, May 25, 1918-2018

Gamma Sigma Delta, Nebraska Chapter: Bylaws and Other Documents

First paragraph:

GAMMA SIGMA DELTA is a faculty governed society that selects its members from junior and senior students, graduate students, faculty, and alumni for the promotion and recognition of high achievement. While Gamma Sigma Delta is an honor society of agriculture, it may elect members from related fields such as biology, botany, chemistry, economics, entomology, family and consumer sciences, forestry, natural resources, plant pathology, sociology, statistics, veterinary medicine, or zoology when the work of the individual is related to agriculture. Officers, committee chairpersons, and others leading the chapter are faculty or alumni.


The Expansion Of The Brazilian Winter Corn Crop And Its Impact On Price Transmission, Fabio L. Mattos, Rodrigo Lanna Franco Da Silveira Jan 2018

The Expansion Of The Brazilian Winter Corn Crop And Its Impact On Price Transmission, Fabio L. Mattos, Rodrigo Lanna Franco Da Silveira

Department of Agricultural Economics: Faculty Publications

The purpose of this study is to analyze the impact of the growth of the Brazilian winter corn crop on the dynamics between domestic Brazilian prices and international prices as well as spot and futures prices in Brazil. Econometric time-series methods tests were applied using Brazilian spot and futures prices and U.S. futures prices. The statistical analysis found evidence that a long-run relationship between Brazilian and U.S. prices had developed, and the Brazilian futures market developed a more dominant role in the relationship between spot and futures prices domestically. These findings were particularly noticeable after 2002, when expanding corn production …


Value Of Arrival Metaphylaxis In U.S. Cattle Industry, Elliott James Dennis, Ted C. Schroeder, David G. Renter, Dustin L. Pendell Jan 2018

Value Of Arrival Metaphylaxis In U.S. Cattle Industry, Elliott James Dennis, Ted C. Schroeder, David G. Renter, Dustin L. Pendell

Department of Agricultural Economics: Faculty Publications

Although several studies have estimated economic impacts of antimicrobials for growth promotion, little is known about economic impacts of the common animal health management strategy known as metaphylaxis: administering antimicrobials to groups of animals to prevent disease. This article develops a new framework to map animal disease to producer profitability and determine societal economic impacts surrounding metaphylactic use of antimicrobials in beef cattle production. Results indicate the direct net return value of metaphylaxis to the U.S. fed cattle industry is at least $532 million. Beef producer surplus losses of $1.8 billion would be associated with eliminating metaphylaxis.


Nebraska Farm Real Estate Market Highlights 2017–2018, Jim Jansen, Jeffrey Stokes Jan 2018

Nebraska Farm Real Estate Market Highlights 2017–2018, Jim Jansen, Jeffrey Stokes

Department of Agricultural Economics: Faculty Publications

2018 Nebraska Agricultural Land Values

Table 1 Average Reported Value of Nebraska Farmland for Different Land Types by Agricultural Statistics District, February 1, 2018

Table 2 2018 Values and Recent Trends by Area of the State

Table 3 2018 Values and Recent Trends by Land Class in Nebraska

2018 Land Values Ranges

Table 4 Average Reported Value Per Acre of Nebraska Farmland for Different Types and Grades of Land in Nebraska by Agricultural Statistics District, February 1, 2018

2018 Net Rates of Return to Agricultural Land

Table 5 Estimated Annual Net Rates of Return by Type of Land and Agricultural …


University Of Nebraska- Lincoln: Fact Book 2017-2018 Jan 2018

University Of Nebraska- Lincoln: Fact Book 2017-2018

University of Nebraska-Lincoln Administration: Reports, Papers, Publications, and Presentations

Table of Contents

Front Cover.................................................................................................. 1

Introduction ....................................................................................................... 2

Table of Contents ............................................................................................. 3

General Information

University of Nebraska-Lincoln Core Values (LEADERS) ................................ 6

University of Nebraska-Lincoln Mission ......................................................... 7

The Missions of the University of Nebraska-Lincoln .......................................... 7

Teaching.................................................................................................... 8

Research.......................................................................................................... 8

Service ............................................................................................................. 9

Institutional and Professional Accreditations.........................................................10

University of Nebraska-Lincoln Administrative Organization Chart ..................14

Student Credit Hours (SCH)

Total SCH: Fall Semester Since 1979 ............................................................15

Total SCH: Spring Semester Since 1993 ......................................................16

SCH by College and Course Level, Fall and Spring Semester, 5 Year Trend .......17

SCH by College and Course Level, Fall Semester, 5 Year Trend …


The Future Of Textiles: Disruption And Collaboration, Susan Brown, Matilda Mcquaid, David Breslauer, Suzanne Lee, Anais Missakian, Abby-George Erikson, Salem Van Der Swaagh Jan 2018

The Future Of Textiles: Disruption And Collaboration, Susan Brown, Matilda Mcquaid, David Breslauer, Suzanne Lee, Anais Missakian, Abby-George Erikson, Salem Van Der Swaagh

Textile Society of America: Symposium Proceedings

The textile field, while not “local” in the geographic sense, is a community: a group of people with a shared language, history, and practices that date back thousands of years. As deeply-rooted as those materials and practices are, textiles is also an area that has historically experienced enormous disruptions due to changing technology and globalization. In the 21st century, we are undergoing something like a second Industrial Revolution. Advances in digital and robotic technologies and shifting labor markets are driving a revolution in where and how things are made. Global climate change, lack of food security for much of …


Wrapped In Wool: Coast Salish Wool Weaving, Vancouver’S Public Art, And Unceded Territory, Alison Ariss Jan 2018

Wrapped In Wool: Coast Salish Wool Weaving, Vancouver’S Public Art, And Unceded Territory, Alison Ariss

Textile Society of America: Symposium Proceedings

Coast Salish blankets, lovingly woven with hand dyed, home spun, and commercially produced yarns, adorn the walls of an international airport, museum, universities, and national broadcasting studio, and a mixed-use development project in Vancouver. All of these publicly accessible sites are located in unceded Coast Salish territory, upon which this city exists. These weavings present a conundrum. Simultaneously viewed as public art and symbols of cultural revitalization, their recognition as fine art has been limited, as most discourse about Coast Salish blankets has occurred outside of the discipline of art history. How then, have these weavings found their way into …


Schoolgirl Embroideries: Integrating Indigenous Motifs, Materials, And Text, Lynne Anderson Jan 2018

Schoolgirl Embroideries: Integrating Indigenous Motifs, Materials, And Text, Lynne Anderson

Textile Society of America: Symposium Proceedings

Hand embroidery was an integral part of female education in Europe, America, and their colonized territories until the late 19th century. All girls embroidered at least one sampler and many stitched more than one. Because needlework was part of the school’s curriculum; a sampler’s composition, technique, and text communicate a great deal about the teacher’s goals, as well as community and family expectations, including those of indigenous students. This presentation explores ways in which indigenous motifs, materials, and text were integrated into schoolgirl samplers and other girlhood embroideries, leaving visible evidence of cross-cultural accommodations. Motifs are recurring patterns or …


The Embroidery Artisans Of The Kashmir Valley: Cultural Imports And Exports From Historical And Contemporary Perspectives., Deborah Emmett Jan 2018

The Embroidery Artisans Of The Kashmir Valley: Cultural Imports And Exports From Historical And Contemporary Perspectives., Deborah Emmett

Textile Society of America: Symposium Proceedings

On a visit to the Kashmir Valley in northern India during the winter months I was given a pheran to wear. This long woolen garment is the customary apparel worn by Kashmiri men and women in cold weather. While the men’s are plain, the women’s pherans are embroidered on the front and sleeves. The skills of those Kashmiri artisans who hand embroider clothing such as the pherans, shawls, and other textiles including rugs, curtains, and cushions are well recognized in India and beyond. Considering the Kashmir Valley’s geographic position surrounded by the Himalayan Mountains, I presumed that their embroidery crafts …


Fish In The Desert – North Africa’S Textile Tradition Between Indigenous Identity And Exogenous Shifts In Meaning, Silvia Dolz Jan 2018

Fish In The Desert – North Africa’S Textile Tradition Between Indigenous Identity And Exogenous Shifts In Meaning, Silvia Dolz

Textile Society of America: Symposium Proceedings

Among the oldest handcraft products of North Africa are woven, knotted, and embroidered textiles (flat woven fabrics, knotted carpets, clothing) primarily made of wool and hair from sheep, goats, or camels. Those products have great importance, beyond their practical purpose, as a communicative and artistic medium. Changes and re-evaluations of the textile from a utilitarian object with potent pre-Islamic and Islamic symbolism towards a modern abstract art object reveal centuries of cultural transfer between the Middle East, North Africa, and Europe on the one hand, and between North and West Africa on the other. At the same time, this has …


Reawakening Chahta Nan Tvnna (Choctaw Textiles), Jennifer Byram Jan 2018

Reawakening Chahta Nan Tvnna (Choctaw Textiles), Jennifer Byram

Textile Society of America: Symposium Proceedings

Choctaw people have crafted textiles from the land for thousands of years. Native to Mississippi and Alabama, U.S.A., the Choctaw Nation of Oklahoma resides today in the Southeastern part of the state and numbers over 200,000 citizens. This paper comes out of the tribe’s Historic Preservation department’s work in conjunction with community efforts to reawaken Chahta nan tvnna, Choctaw textiles. By piecing together disparate parts of the Choctaw textile narrative, the Choctaw community is creating new textile work that recalls the ancestors and brings the identity of Chahta nan tvnna to new generations of Choctaw artisans.


Batik Of Java: Global Inspiration, Maria Wronska-Friend Jan 2018

Batik Of Java: Global Inspiration, Maria Wronska-Friend

Textile Society of America: Symposium Proceedings

Batik, the technique of patterning cloth through the application of wax, reached the highest level of complexity on the island of Java. While deeply embedded in local traditions and associated with the social order of Java, outside Indonesia batik became a powerful cultural intermediary connecting countries as diverse as Netherlands, Japan, Ghana, India, and Australia. In the early stages, this process was an outcome of the Dutch colonial agency. In the 17th and 18th centuries the Dutch East India Company sold Indian textiles destined for Indonesian markets as well as small quantities of Javanese batiks to the Japanese. …


Shipibo-Conibo Textiles 2010-2018: Artists Of The Amazon Culturally Engaged, Nancy Gardner Feldman Jan 2018

Shipibo-Conibo Textiles 2010-2018: Artists Of The Amazon Culturally Engaged, Nancy Gardner Feldman

Textile Society of America: Symposium Proceedings

This paper considers the intersection of processes of making and cultural memory as contemporary Shipibo artists design, produce, and exchange of their contemporary textiles and art. One sees a continuation of traditional collaborative social networks both in Peru’s deep Amazon region and in new Shipibo communities of Pucallpa and Lima. In cities, they create new artistic networks and expressions of art in ceremony. In these artworks, one sees how Shipibo relationship to the natural world, the forest, plants, animals, and waters reflects deep spiritual beliefs, wisdom, and community knowledge. Shipibo communities in 2017 face ever-expanding challenges from intrusions into their …


Weaving Authenticity: Artesanías Or The Art Of The Textile In Chiapas Mexico, Addison Nace Jan 2018

Weaving Authenticity: Artesanías Or The Art Of The Textile In Chiapas Mexico, Addison Nace

Textile Society of America: Symposium Proceedings

During my six months in Chiapas, I worked for the weaving cooperative Mujeres Sembrando la Vida (MSV), a partner organization to Natik. Natik works with grassroots organizations in Mexico and Guatemala with a focus on economic development and education. MSV is a cooperative of sixty women weaving from the municipality of Zinacantán1 founded by Doña Magdalena and currently run by her two daughters Yoli and Xunka. Zinacantán is a Tzotzil Mayan village in the highlands of Chiapas, Mexico. Chiapas has the highest population of indigenous people and is also the poorest state in Mexico with a poverty rate of 75.7 …


Looking At The Past And Current Status Of Kenya’S Clothing And Textiles, Mercy V.W. Wanduara Jan 2018

Looking At The Past And Current Status Of Kenya’S Clothing And Textiles, Mercy V.W. Wanduara

Textile Society of America: Symposium Proceedings

This paper analyzes and documents traditional textiles and clothing of the Kenyan people before and after independence in 1963. The paper is based on desk top research and face to face interviews from senior Kenyan citizens who are familiar with Kenyan traditions. An analysis of some of the available Kenya’s indigenous textile fiber plants is made and from which a textile craft basket is made. Kenya’s textile and clothing industry has undergone tremendous changes from pre-colonial era (before 1963) to date. Traditionally Kenyans donned clothing made out locally available materials; namely plants and animal skin. Color for these materials was …


The Global Influence Of China And Europe On Local Japanese Tapestries Mainly From The 19th Through Early 20th Centuries, Masako Yoshida Jan 2018

The Global Influence Of China And Europe On Local Japanese Tapestries Mainly From The 19th Through Early 20th Centuries, Masako Yoshida

Textile Society of America: Symposium Proceedings

In general, Japanese culture has developed under the influence of foreign cultures, and textiles are no exception. In this presentation, I will focus on tapestries from the 19th century (the late Edo period) to the early 20th century (the Showa period), and discuss how Japanese tapestries achieved their original expression under the influence of Chinese and European tapestries. The Japanese began to seriously produce tapestry weaving around the end of the Edo period, but in the beginning, they just copied Chinese and European tapestries. Regarding these early productions, little research has been accomplished yet. In this presentation, I …


Cottage Industry As Social Practice: Sustainability Of Handweaving In The Post-Industrialist Era, Maggie Leininger Jan 2018

Cottage Industry As Social Practice: Sustainability Of Handweaving In The Post-Industrialist Era, Maggie Leininger

Textile Society of America: Symposium Proceedings

India to Appalachia: How Cottage Industries Preserve Textile Heritage examines the role of the hand weaver and the cottage industry from India to the American Craft Revival in promoting cultural identity through textiles. The migratory nature of textile production both in the pre-and post-industrial practices has long challenged the notion of a pure textile heritage for any culture. However, with the almost simultaneous appearance of Khadi production in India and the American Craft Revival of Appalachia, the allure of the homespun as a cultural asset became a mechanism to offset the impact of textile industrialization. As urban centers increased in …


Mind’S Eye And Embodied Weaving: Simultaneous Contrasts Of Hue In Isluga Textiles, Northern Chile, Penelope Dransart Jan 2018

Mind’S Eye And Embodied Weaving: Simultaneous Contrasts Of Hue In Isluga Textiles, Northern Chile, Penelope Dransart

Textile Society of America: Symposium Proceedings

This article examines the use of hue in textiles woven during the twentieth century in Isluga, a bilingual Aymara/Spanish-speaking community of herders of llamas, alpacas and sheep in the highlands of northern Chile. It pays tribute to the weaving skills of Natividad Castro Challapa and other weavers of her generation, born early in the twentieth century. Aniline dyes were already known to them but, in the course of their lives, they witnessed increasing amounts of industrially manufactured, pre-dyed acrylic yarns arriving in the community. The article explores how weavers incorporated these brightly hued yarns in their textiles to form accents …


The Fabric Of War: Wool And Local Land Wars In A Global Context, Madelyn Shaw, Trish Fitzsimons Jan 2018

The Fabric Of War: Wool And Local Land Wars In A Global Context, Madelyn Shaw, Trish Fitzsimons

Textile Society of America: Symposium Proceedings

During the nineteenth century, exponential growth in sheep pastoralism in Australia and New Zealand, and in less predictable locales such as the Sandwich Islands (Hawaii) and Rapanui (Easter Island), fueled the alienation of Indigenous peoples from their lands. The sheep and their wool, at the heart of these ‘grass wars,’ fed a global industry that supported another kind of war – the mass, cold climate warfare characterizing the century between the Crimean and Korean wars. Not until the second quarter of the nineteenth century did mechanization and factory organization affect wool production, as assiduous Australasian sheep husbandry bred wool staples …


Abstracts Of Papers: Textile Society Of America 16th Biennial Symposium Jan 2018

Abstracts Of Papers: Textile Society Of America 16th Biennial Symposium

Textile Society of America: Symposium Proceedings

Abstracts of 175 papers:

Monisha Ahmed — The Kashmir / Cashmere Shawl – Tradition and Transformation

Philis Alvic — Eliza Calvert Hall, The Handwoven Coverlet Book, and Collecting Coverlet Patterns in Early Twentieth Century Appalachia

Sarah Amarica — Global Threads: Histories of Labour and Cloth in Ann Hamilton and Ibrahim Mahama’s Installation Art

Lynne Anderson — Schoolgirl Embroideries: Integrating Indigenous Motifs, Materials, and Text

Jennifer Angus — Education through Co-Design

Margaret Olugbemisola Areo and Adebowale Biodun Areo — Egungun: Concept, Content and the Dynamic Contextual Manifestations of Yoruba Ancestors Masquerade

Alison Ariss — Wrapped in Wool: Coast Salish wool weaving, …


Mammalian Pathogenesis And Transmission Of Avian Influenza A(H7n9) Viruses, Tennessee, Usa, 2017, Jessica A. Belser, Nicole Brock, Xiangjie Sun, Joyce Jones, Natosha Zanders, Erin Hodges, Joanna A. Pulit-Penaloza, David Wentworth, Terrence M. Tumpey, Todd Davis, Taronna R. Maines Jan 2018

Mammalian Pathogenesis And Transmission Of Avian Influenza A(H7n9) Viruses, Tennessee, Usa, 2017, Jessica A. Belser, Nicole Brock, Xiangjie Sun, Joyce Jones, Natosha Zanders, Erin Hodges, Joanna A. Pulit-Penaloza, David Wentworth, Terrence M. Tumpey, Todd Davis, Taronna R. Maines

United States Public Health Resources

Infections with low pathogenicity and highly pathogenic avian influenza A(H7N9) viruses affected poultry in 4 states in the southeastern United States in 2017. We evaluated pathogenicity and transmission of representative viruses in mouse and ferret models and examined replication kinetics in human respiratory tract cells. These viruses can cause respiratory infections in mammalian models.


Methylation-Based Enrichment Facilitates Low-Cost, Noninvasive Genomic Scale Sequencing Of Populations From Feces, Kenneth L. Chiou, Christina M. Bergey Jan 2018

Methylation-Based Enrichment Facilitates Low-Cost, Noninvasive Genomic Scale Sequencing Of Populations From Feces, Kenneth L. Chiou, Christina M. Bergey

United States Public Health Resources

Obtaining high-quality samples from wild animals is a major obstacle for genomic studies of many taxa, particularly at the population level, as collection methods for such samples are typically invasive. DNA from feces is easy to obtain noninvasively, but is dominated by bacterial and other non-host DNA. The high proportion of non-host DNA drastically reduces the efficiency of high-throughput sequencing for host animal genomics. To address this issue, we developed an inexpensive capture method for enriching host DNA from noninvasive fecal samples. Our method exploits natural differences in CpG-methylation density between vertebrate and bacterial genomes to preferentially bind and isolate …


Therapeutic And Immunological Interventions In Primary Biliary Cholangitis: From Mouse Models To Humans, Atsushi Tanaka, Patrick S.C. Leung, Howard A. Young, M. Eric Gershwin Jan 2018

Therapeutic And Immunological Interventions In Primary Biliary Cholangitis: From Mouse Models To Humans, Atsushi Tanaka, Patrick S.C. Leung, Howard A. Young, M. Eric Gershwin

United States Public Health Resources

Primary biliary cholangitis (PBC) is a chronic cholestatic liver disease that predominantly affects women in their fifth and sixth decades. The diagnostic hallmarks of PBC are detection of anti-mitochondrial antibodies (AMAs) and chronic non-suppurative destructive cholangitis (CNSDC) of small- and medium-sized intrahepatic bile ducts in liver histological examination [1, 2]. A significant amount of data suggests that immunological activity against small biliary epithelial cells (BECs), found histologically as portal inflammation, leads to clinical disease. In PBC, as with other autoimmune diseases, both genetic and environmental factors contribute to the development of pathology [3–8]. The first-line therapy of PBC is ursodeoxycholic …


Copd National Action Plan Jan 2018

Copd National Action Plan

United States Natonal Institutes of Health: Materials

The COPD National Action Plan is the first-ever blueprint for a multi-faceted, unified fight against the disease. Developed at the request of Congress.