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Articles 1471 - 1500 of 9027
Full-Text Articles in Entire DC Network
How To Play The Blues, Rosanna Durst
Full Issue, Journal Editors
Understanding Vaccines Topic For Virtual Oxford Science Cafe, Edwin B. Smith
Understanding Vaccines Topic For Virtual Oxford Science Cafe, Edwin B. Smith
University of Mississippi News
UM biologist to discuss types, safety and side effects during Jan. 19 event on Zoom
Andrea Jekabsons Named Um Chief Human Resources Officer, Lisa Stone
Andrea Jekabsons Named Um Chief Human Resources Officer, Lisa Stone
University of Mississippi News
Experienced HR professional has led improvements to campus employee and wellness programs
Cis-Trimethoxystilbene, Exhibits Higher Genotoxic And Antiproliferative Effects Than Its Isomer Trans-Trimethoxystilbene In Mcf-7 And Mcf-10a Cell Lines, Natália Dos Santos Gonçalves, Tamires Maria Silva Pereira De Mello, Cássia Suemi Mizuno, Saqlain Haider
Cis-Trimethoxystilbene, Exhibits Higher Genotoxic And Antiproliferative Effects Than Its Isomer Trans-Trimethoxystilbene In Mcf-7 And Mcf-10a Cell Lines, Natália Dos Santos Gonçalves, Tamires Maria Silva Pereira De Mello, Cássia Suemi Mizuno, Saqlain Haider
Faculty and Student Publications
Stilbenes are a class of natural compounds with a wide variety of biological effects, such as antitumor activity. The best-known stilbene is resveratrol, whose clinical application is limited due to its low bioavailability. Methoxylated derivatives of this stilbene, including cis-trimethoxystilbene (cis-TMS) and trans-trimethoxystilbene (trans-TMS) have demonstrated more pronounced cytotoxic and anti-proliferative effects than resveratrol. Thus, the objective of this study is to evaluate and compare the cytotoxicity and antiproliferative effects of cis-and trans-TMS in MCF-7 and its normal counterpart MCF-10A. Both compounds were cytotoxic, genotoxic, and induced G2-M accumulation and cell death in the two cell lines. These results suggested …
Eucalyptus Cinerea: Microscopic Profile, Chemical Composition Of Essential Oil And Its Antioxidant, Microbiological And Cytotoxic Activities, Matheus Saukoski Pauzer, Thais De Oliveira Borsato, Valter Paes De Almeida, Vijayasankar Raman
Eucalyptus Cinerea: Microscopic Profile, Chemical Composition Of Essential Oil And Its Antioxidant, Microbiological And Cytotoxic Activities, Matheus Saukoski Pauzer, Thais De Oliveira Borsato, Valter Paes De Almeida, Vijayasankar Raman
Faculty and Student Publications
Eucalyptus species possess anti-inflammatory, antifungal, antibacterial, and insecticidal properties. In this study, the chemical composition and biological activities of Eucalyptus cinerea essential oil (EO) and the leaf and stem anatomy were investigated. EO was extracted by Clevenger apparatus and the compounds were identified by GC/MS. The antioxidant activity was evaluated by DPPH, ABTS, and reducing phosphomolybdenum complex. Broth microdilution was used to determine antimicrobial activity. Cytotoxicity was verified against HeLa, HRT-18, and Calu-3 cells by MTT assay. The cytotoxic mechanism was studied by cell DNA content, cell cycle, and DNA fragmentation. The microscopic analyzes of the leaves and the stems …
Isolation Of Catechins From Cycas Armstrongii Miq. Of An Egyptian Origin, Ahmed Ismail, Mohamed M. Radwan, Hossam M. Hassan, Abeer S. Moawad
Isolation Of Catechins From Cycas Armstrongii Miq. Of An Egyptian Origin, Ahmed Ismail, Mohamed M. Radwan, Hossam M. Hassan, Abeer S. Moawad
Faculty and Student Publications
The phytochemical investigation of Cycas armstrongii Miq. leaves and twigs using different chromatographic techniques led to the isolation of three catechin monomers; catechin (1), epicatechin (2), and epigallocatechin-3-gallate (3), for the first time from this species. The chemotaxonomic significance of the isolated compounds is discussed in the rest of this article.
Expression Of Trefoil Factor 3 Is Decreased In Colorectal Cancer, Ingrid Espinoza, Sumit Agarwal, Amit Reddy, Veena Shenoy
Expression Of Trefoil Factor 3 Is Decreased In Colorectal Cancer, Ingrid Espinoza, Sumit Agarwal, Amit Reddy, Veena Shenoy
Faculty and Student Publications
In colorectal cancer (CRC), high expression of trefoil factor 3 (TFF3) is associated with tumor progression and reduced patient survival; however, bioinformatics analyses of public 'omics' databases show low TFF3 expression in CRCs as compared to normal tissues. Thus, we examined TFF3 expression in CRCs and matching normal tissues to evaluate its role in CRC progression. TFF3 gene expression was char- acterized using the bioinformatics portal UALCAN (http:// ualcan.path.uab.edu). Tissue microarrays (TMAs) of archival CRC specimens (n=96) were immunostained with anti-human TFF3 antibodies. Immunohistochemical (IHC) staining intensity was semi-quantitatively scored. For this cohort, the median follow-up was 5.4 years. Associations …
Exploring The Chemical Space Of 1,2,3-Triazolyl Triclosan Analogs For Discovery Of New Antileishmanial Chemotherapeutic Agents, Julia Fernández De Luco, Alejandro I. Recio-Balsells, Diego G. Ghiano, Ana Bortolotti
Exploring The Chemical Space Of 1,2,3-Triazolyl Triclosan Analogs For Discovery Of New Antileishmanial Chemotherapeutic Agents, Julia Fernández De Luco, Alejandro I. Recio-Balsells, Diego G. Ghiano, Ana Bortolotti
Faculty and Student Publications
Triclosan and isoniazid are known antitubercular compounds that have proven to be also active againstLeishmaniaparasites. On these grounds, a collection of 37 diverse 1,2,3-triazoles based on the antitubercular molecules triclosan and 5-octyl-2-phenoxyphenol (8PP) were designed in search of novel structures with leishmanicidal activity and prepared using different alkynes and azides. The 37 compounds were assayed againstLeishmania donovani, the etiological agent of leishmaniasis, yielding some analogs with activity at micromolar concentrations and againstM. tuberculosisH37Rv resulting in scarce active compounds with an MIC of 20 μM. To study the mechanism of action of these catechols, we analyzed the inhibition activity of the …
2021 Women's Tennis Fact Book, Ole Miss Athletics. Women's Tennis
2021 Women's Tennis Fact Book, Ole Miss Athletics. Women's Tennis
Women's Tennis
No abstract provided.
Serial-Multiple Mediation Of Enjoyment And Intention On The Relationship Between Creativity And Physical Activity, Myungjin Jung, Han Soo Kim, Paul D. Loprinzi, Minsoo Kang
Serial-Multiple Mediation Of Enjoyment And Intention On The Relationship Between Creativity And Physical Activity, Myungjin Jung, Han Soo Kim, Paul D. Loprinzi, Minsoo Kang
Faculty and Student Publications
The purpose of the present study was to examine a serial-multiple mediation of physical activity (PA) enjoyment and PA intention in the relationship between creativity and PA level (i.e., moderate-to-vigorous PA). A total of 298 undergraduate and graduate students completed a selfreported questionnaire evaluating creativity, PA enjoyment, PA intention, and PA level. Data analysis was conducted using descriptive statistics, Pearson correlation coefficient, ordinary leastsquares regression analysis, and bootstrap methodology. Based on the research findings, both PA enjoyment (β = 0.06; 95% CI [0.003, 0.12]) and PA intention (β = 0.08; 95% CI [0.03, 0.13]) were found to be a mediator …
New Benzoxazole Derivatives As Antiprotozoal Agents: In Silico Studies, Synthesis, And Biological Evaluation, Mohamed A. Abdelgawad, Mohammad M. Al-Sanea, Mohamed A. Zaki, Enas I.A. Mohamed
New Benzoxazole Derivatives As Antiprotozoal Agents: In Silico Studies, Synthesis, And Biological Evaluation, Mohamed A. Abdelgawad, Mohammad M. Al-Sanea, Mohamed A. Zaki, Enas I.A. Mohamed
Faculty and Student Publications
Background. Benzoxazole derivatives have different biological activities. In pursuit of designing novel chemical entities with antiprotozoal and antimicrobial activities, benzoxazolyl aniline was utilized as a privileged scaffold of a series of (3-benzoxazole-2-yl) phenylamine derivatives, 3-benzoxazoloyl acetamide, and butyramide derivatives. Methods. These novel analogs were synthesized in straightforward simple chemistry without any quantitative chromatographic separations in reasonable yields. The biological evaluation of all target compounds as potential antimalarial, antileishmanial, antitrypanosomal, and antimicrobial agents was performed by various well-established cell-based methods. Results. Compounds 6d and 5a showed promising biological screening data. The amidation of 3-benzoxazolyl aniline 1 with the chloroacetyl functional group …
Mythopoetic Naturalization: Toward A New Paradigm Of Reifcation, Bryan Smyth
Mythopoetic Naturalization: Toward A New Paradigm Of Reifcation, Bryan Smyth
Faculty and Student Publications
This paper sketches a new approach to the critical-theoretic problem of reifcation understood as a normatively problematic form of naturalizing or dehistoricizing entifcation. Entifcation in general is approached phenomenologically in terms of the mythic outer horizonality of the lifeworld, and reifcation is shown to stem from the dichotomy between nature and history which, along with a corresponding dichotomy between myth and reason, is characteristic of Enlightenment rationality. Dereifcation necessitates overcoming these dichotomies, and this implies a critical embrace of myth and mythopoesis in the sense of instituting more normatively appropriate lifeworld horizons. While classical Marxism and radical social theory have …
The Effects Of Acute Exercise On Short-And Long-Term Memory: Considerations For The Timing Of Exercise And Phases Of Memory, Paul D. Loprinzi, Sierra Day, Rebecca Hendry, Sara Hoffman, Alexis Love, Sarah Marable, Elizabeth Mckee, Sydney Stec, Hanna Watson, Brittney Gilliland
The Effects Of Acute Exercise On Short-And Long-Term Memory: Considerations For The Timing Of Exercise And Phases Of Memory, Paul D. Loprinzi, Sierra Day, Rebecca Hendry, Sara Hoffman, Alexis Love, Sarah Marable, Elizabeth Mckee, Sydney Stec, Hanna Watson, Brittney Gilliland
Faculty and Student Publications
The specific questions addressed from this research include: (1) Does high-intensity acute exercise improve memory?, (2) If so, do the mechanisms occur via encoding, consolidation, or retrieval? and (3) If acute exercise occurs in multiple phases of memory (e.g., before encoding and during consolidation), does this have an additive effect on memory? Three experimental, within-subject, counterbalanced studies were conducted among young adults. High-intensity exercise involved a 20-minutes bout of exercise at 75% of heart rate reserve. Memory was evaluated from a word-list task, including multiple evaluations out to 24-hours post-encoding. The timing of the exercise and memory assessments were carefully …
Applied Statistics Course Offerings: Spring 2021, University Of Mississippi. Graduate School
Applied Statistics Course Offerings: Spring 2021, University Of Mississippi. Graduate School
GMAS Course List
No abstract provided.
Elucidating The Interfacial Interactions Between Biomacromolecules And Functionalized Pamam-Based Materials For Biomedical Applications, Briana L. Simms
Elucidating The Interfacial Interactions Between Biomacromolecules And Functionalized Pamam-Based Materials For Biomedical Applications, Briana L. Simms
Electronic Theses and Dissertations
Polyamidoamine (PAMAM) is a dendrimer structure with a polypeptide backbone architecture. It has been utilized in a wide variety of applications but has found significant utility in biomedical applications. PAMAM has been studied extensively due to its globular structure that is similar to proteins found in the body. The branched architecture and overall size provide a favorable environment for host-guest interactions and allows for the loading of small molecules for therapeutic delivery. Although PAMAM has many benefits for use in the area of therapeutic delivery, a primary area of concern for this molecular architecture is the terminal amines that serve …
Surface And Interfacial Phenomena Between Soil And Oil, Md Firoz Ahmed
Surface And Interfacial Phenomena Between Soil And Oil, Md Firoz Ahmed
Electronic Theses and Dissertations
Crude oil and motor oil spills on land have severe environmental consequences that pose threats to both humans and natural resources. It is particularly important to know the flow behavior of oils to protect terrestrial ecosystems from this kind of damage. The spreading kinetics, contact angle (CA), and droplet baseline studies of crude oil and motor oils were investigated over several realistic soil-based matrices composed of topsoil (silt-dominant), sand, clay, and moisture. It was found that with an increase in moisture content (MC), the spreading area decreased, and initial spreading time increased for all given oil. The initial CA generally …
A Spectroscopic And Quantum Chemical Investigation Into The Noncovalent Interactions And Charge Accommodation Of Biomolecules And Their Building Blocks In Various Environments, Ashley Elizabeth Williams
A Spectroscopic And Quantum Chemical Investigation Into The Noncovalent Interactions And Charge Accommodation Of Biomolecules And Their Building Blocks In Various Environments, Ashley Elizabeth Williams
Electronic Theses and Dissertations
As optical measurements have grown increasingly more precise with the rage of the technological revolution, the computer’s ability has matched in computing speed to produce accurate quantum chemical predictions of systems ranging from the atomic to multi-molecular levels. Application of spectroscopy in the investigation of the structure and function of biomolecules and their building blocks has a rich literature background, with applications among cancer research, charge transfer and energy storage, and drug design and delivery. The focus of this dissertation is thus a quantum chemical and/or spectroscopic investigation of a series of biomolecules which include the vibrational band positions of …
On Domination And Bondage Numbers Of Some Classes Of Graphs, Andrew Pham
On Domination And Bondage Numbers Of Some Classes Of Graphs, Andrew Pham
Electronic Theses and Dissertations
Given a simple finite graph G=(V,E), a vertex subset D ? V(G) is said to be a dominating set of G if every vertex v ? V(G)-D is adjacent to a vertex in D. The domination number of G, denoted ?(G), is the minimum cardinality among all dominating sets of G. In a network, the domination number determines the minimum number of sites required to dominate the entire network at a minimum cost. The bondage number of a graph G is the minimum cardinality among all edge sets B such that ?(G-B) > ?(G). The bondage number may serve as a …
The Ole Miss, University Of Mississippi
The Ole Miss, University Of Mississippi
The Ole Miss (1897-)
The Ole Miss Annual, 2021
Isolation Of Marker Compounds From Copaiba Essential Oil And Mimosa Pigra For Quality Evaluation Of Dietary Supplements, Mohammed Hawwal
Isolation Of Marker Compounds From Copaiba Essential Oil And Mimosa Pigra For Quality Evaluation Of Dietary Supplements, Mohammed Hawwal
Electronic Theses and Dissertations
Natural products have been used as a primary means of treating illness since ancient times, and they remain an important pool of U.S. FDA approved drugs. Approximately 33% of all current pharmaceutical medications discovered between 1981 and 2014 are either natural products or derived from natural products (Newman and Cragg 2016). The process of isolating specialized metabolites from medicinal plants has led to the development of particularly important medicines worldwide (Rakotomalala, Agard et al. 2013) such as Taxol® from Taxus brevifolia Nutt. (Taxaceae) and salicylic acid from the bark of Salix spp. This research is composed of five chapters; the …
Engineer Micro- And Nano-Sized Polymeric Particles For Drug Delivery Using Advanced Multivariate Statistical Tools, Bhavani Prasad Vinjamuri
Engineer Micro- And Nano-Sized Polymeric Particles For Drug Delivery Using Advanced Multivariate Statistical Tools, Bhavani Prasad Vinjamuri
Electronic Theses and Dissertations
Particulate drug delivery systems are gaining considerable attention in recent years due to increasing advantages for an effective delivery of therapeutics. Application of advanced particle engineering technologies in polymeric drug delivery systems has shown to improve the efficacy of a drug substance by maintaining stable levels in the blood when compared to traditional parenteral drug products. However, development of these products is a complex multifaceted process with numerous challenges. Formulation development scientists need to comprehend and control a range of unit manufacturing operations along with the formulation composition for a successful product. Therefore, the objective of this project is to …
Serving Motherhood: Analyzing The Balance And Justice Of Foodwork In The Lives Of Working Moms, Kaitlyn Paige Hall
Serving Motherhood: Analyzing The Balance And Justice Of Foodwork In The Lives Of Working Moms, Kaitlyn Paige Hall
Electronic Theses and Dissertations
This thesis focuses on the foodwork that working mothers do at work and at home in order to support and provide for their families. It explores how women in low-paid food service jobs talk about and manage the work of feeding their families at home and customers at work in order to better understand the gender dynamics of this work and the conditions necessary to achieve “work-family justice”—structural solutions to work/family conflict. The study is based on qualitative semi-structured, in-depth interviews with 12 mothers who are between the ages of 24 and 43 from Mississippi and Arkansas. While some held …
Understanding Willingness Towards Deprescribing Among Older Adults With Osteoporosis, Queenie Paltanwale
Understanding Willingness Towards Deprescribing Among Older Adults With Osteoporosis, Queenie Paltanwale
Electronic Theses and Dissertations
Objectives: To describe and identify the socio-behavioral factors predicting willingness towards deprescribing among older adults with osteoporosis.Design, Setting, and Participants: For this population-based survey study of US Medicare beneficiaries, data was obtained from the Medication Attitudes Module distributed to the participants in Round 6 (2015) of the National Health and Aging Trends Study. Our study population consisted to respondents who were diagnosed with osteoporosis in round 6 or earlier and who responded to the Medication Attitude Module. Main outcome and Measures: Response to the statement “I would like to reduce the number of medicines I am taking” was the main …
Removal Of Heavy Metals From Water Using Natural Bauxite, Hashindra Kumari Herath
Removal Of Heavy Metals From Water Using Natural Bauxite, Hashindra Kumari Herath
Electronic Theses and Dissertations
Bauxite, the principal ore of aluminum is a potential low-cost sorbent to treat heavy metal-contaminated water. This work studied the ability of raw bauxite to adsorb Pb2+, Cu2+ , Ni2+, and Co2+ ions in natural waters and the dependency of the sorption efficiency on the initial metal ion concentration in water, contact time, the ‘type’ of bauxite, and the effect of coexisting metals. Goethite-rich (B1) and kaolinite-rich (B2) bauxites were sampled in Pontotoc County, Mississippi. Single element and multi-element (ME) solutions were prepared by introducing the metals at concentrations of 10, 100, and 500 ppb in lake water. The solutions …
Responses Of Predatory Myxobacteria To Prey Signaling Molecules & Features Of A Pseudomonas Prey Avoiding Predation, Shukria Akbar
Responses Of Predatory Myxobacteria To Prey Signaling Molecules & Features Of A Pseudomonas Prey Avoiding Predation, Shukria Akbar
Electronic Theses and Dissertations
Gram-negative unicellular myxobacteria, along with their multicellular lifestyle andbiologically active specialized metabolites, are known for the predatory interactions with Gram-negative/ Gram-positive bacteria and fungi. Although myxobacterial predation range have been exploited extensively, little is known about the prey associated molecules contributing to myxobacterial predator-prey dynamics. By employing transcriptomics and untargeted metabolomics approaches, we demonstrate two structurally distinct classes of signaling molecules from Gram-negative bacterial prey elicit significant omics responses from myxobacteria, Myxococcus xanthus and Cystobacter ferrugineus. An overlapping and general response to acylhomoserine lactones, whereas a distinctive response to a quinolone signaling molecule is observed from both myxobacteria. Similarly, by …
Quantifying Microbial Resistance To Nematode Predation, Tyler Bacon
Quantifying Microbial Resistance To Nematode Predation, Tyler Bacon
Electronic Theses and Dissertations
The selection pressure of predation has encouraged the development of defense traits that can make an individual species more environmentally stable. In addition to biotic pressures, abiotic factors could lead to disruption of predator-prey balance within ecosystems. Consequently, it is significant to better understand how environmental factors can influence predator-prey interactions and how responses may, in turn, affect communities. A current challenge within microbial communities is to understand which intraspecific traits associated with such defense strategies are important for microbial-prey responses to predation, and how the responses vary across environments revealing GxE interactions. In this study, I examined microbial-predator prey …
Responses Of Myxobacteria To Plant-Related Chemosignals Suggests Their Roles In The Rhizobiome, Barbara Iyare Adaikpoh
Responses Of Myxobacteria To Plant-Related Chemosignals Suggests Their Roles In The Rhizobiome, Barbara Iyare Adaikpoh
Electronic Theses and Dissertations
In the rhizosphere, plants curate and maintain distinct rhizobiome, some of which serve as secondary defense mechanisms against pathogenic microorganisms. Additionally, in response to biotic stress, plants generate phytohormones which regulate signaling pathways to activate systemic resistance. These phytohormones contribute to the chemical space within the rhizosphere in addition to other low-molecular-weight metabolites used for cell-to-cell communication within species and across kingdoms. However, little is known about the influences of stress-related phytohormones on beneficial bacteria even though biocontrol strategies abundantly explore plant-beneficial microorganisms to manage pathogens in agricultural systems. Myxobacteria are competent predators of plant pathogens and have demonstrated responses …
Systematic Computational Investigation Of Thermal Barrier Coatings For Cellulose Substrates, Mohammad Mansouriantabaei
Systematic Computational Investigation Of Thermal Barrier Coatings For Cellulose Substrates, Mohammad Mansouriantabaei
Electronic Theses and Dissertations
A statistical central composite design (CCD) was employed to investigate the effects of cellulose nanocrystal (CNC) and cellulose nanofiber (CNF) volume fractions, as well as relative free volume fraction, on the thermal barrier properties of a pigment-based coating for cellulosic substrates composed of calcium carbonate (CaCO3) and a copolymer binder, poly(styrene-co-methacrylic acid). Average room-temperature thermal conductivity (based on three replicates) was selected as a response and calculated for the different coating formulations using reverse non-equilibrium molecular dynamics (RNEMD) simulation with the Müller-Plathe algorithm. A reduced quadratic response surface model was fitted to the response data and analysis of variance (ANOVA) …
A Case Study Correlating Cardiometabolic Markers And T Helper Inflammatory Pathways In Covid-19 Patients, Mohammad Shaheed Nazrul
A Case Study Correlating Cardiometabolic Markers And T Helper Inflammatory Pathways In Covid-19 Patients, Mohammad Shaheed Nazrul
Electronic Theses and Dissertations
COVID-19 is one of the deadliest pandemics in the history of mankind and the infection and mortality rate to this date has been immense. There is several information and data available to analyze patient data regarding both deceased and non-severe patients. A vast amount of research and study is ongoing to understand the implications and cure for this disease. The main purpose of this paper is to find the correlation between inflammatory pathway markers and cardiometabolic markers of COVID-positive patients and to see which T-helper pathway markers are enriched and which markers have reduced count amongst three categories of patients.