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Joint Map Of Warren County, Kentucky, Steven L. Martin, Emily R. Morris Apr 2026

Joint Map Of Warren County, Kentucky, Steven L. Martin, Emily R. Morris

Map and Chart--KGS

This fracture map is a compilation of joint locations and faults mapped in Warren County, Kentucky, and provides orientations of fractures (joints and faults) for hydrological, geotechnical, slope stability, and rockfall mitigation analysis. The joint data include orientations collected from 2023 to 2024, and those collected during the U.S. Geological Survey (USGS) geologic mapping of the Woodburn 7.5 -minute quadrangle (Shawe, 1963c). New joint orientations were measured to fill gaps in the published geologic map data. Joints are fractures with no appreciable movement parallel to the fracture plane and only slight movement normal to the fracture plane, whereas faults exhibit …

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Measurement Of Kaon Directed Flow In Au+Au Collisions In The High Baryon Density Region, B. E. Aboona, J. Adam, G. Agakishiev, I. Aggarwal, M. M. Aggarwal, Z. Ahammed, A. Aitbayev, I. Alekseev, E. Alpatov, A. K. Alshammri, A. Aparin, S. Aslam, J. Atchison, G. S. Averichev, V. Bairathi, X. Bao, P. Barik, K. Barish, S. Behera, P. Bhagat, A. Bhasin, S. Bhatta, I. G. Bordyuzhin, J. D. Brandenburg, A. V. Brandin, C. Broodo, X. Z. Cai, H. Caines, M. Calderón De La Barca Sánchez, D. Cebra, J. Ceska Apr 2026

Measurement Of Kaon Directed Flow In Au+Au Collisions In The High Baryon Density Region, B. E. Aboona, J. Adam, G. Agakishiev, I. Aggarwal, M. M. Aggarwal, Z. Ahammed, A. Aitbayev, I. Alekseev, E. Alpatov, A. K. Alshammri, A. Aparin, S. Aslam, J. Atchison, G. S. Averichev, V. Bairathi, X. Bao, P. Barik, K. Barish, S. Behera, P. Bhagat, A. Bhasin, S. Bhatta, I. G. Bordyuzhin, J. D. Brandenburg, A. V. Brandin, C. Broodo, X. Z. Cai, H. Caines, M. Calderón De La Barca Sánchez, D. Cebra, J. Ceska

Physics and Astronomy Faculty Publications

Rapidity-odd directed flow v 1 measurements are presented for K ± and KS0 in Au + Au collisions for sNN from 3.0 to 3.9 GeV with the STAR experiment. For comparison, v 1 of π ± , protons, and Λ from the same collisions are also discussed. The mid-rapidity v 1 slope dv1/dy|y=0 for protons and Λ is positive in these collisions. On the other hand, v 1 slope of kaons exhibits a strong pT dependence: negative at pT< 0.6 GeV/ c and positive at higher pT. A similar pT dependence is also evident for the v …

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Simulation And Optimization Of The Active Magnetic Shield Of The N2edm Experiment, N. J. Ayres, G. Ban, G. Bison, K. Bodek, V. Bondar, T. Bouillaud, G. L. Caratsch, E. Chanel, W. Chen, C. Crawford, V. Czamler, C. B. Doorenbos, S. Emmeneger, S. K. Ermakov, M. Ferry, M. Fertl, A. Fratangelo, D. Galbinski, W. C. Griffith, Z. D. Grujic, K. Kirch, V. Kletzl, J. Krempel, B. Lauss, T. Lefort, A. Lejuez, K. Michielsen, J. Micko, P. Mullan, O. Naviliat-Cuncic, F. M. Piegsa Apr 2026

Simulation And Optimization Of The Active Magnetic Shield Of The N2edm Experiment, N. J. Ayres, G. Ban, G. Bison, K. Bodek, V. Bondar, T. Bouillaud, G. L. Caratsch, E. Chanel, W. Chen, C. Crawford, V. Czamler, C. B. Doorenbos, S. Emmeneger, S. K. Ermakov, M. Ferry, M. Fertl, A. Fratangelo, D. Galbinski, W. C. Griffith, Z. D. Grujic, K. Kirch, V. Kletzl, J. Krempel, B. Lauss, T. Lefort, A. Lejuez, K. Michielsen, J. Micko, P. Mullan, O. Naviliat-Cuncic, F. M. Piegsa

Physics and Astronomy Faculty Publications

The n2EDM experiment at the Paul Scherrer Institute aims to conduct a high-sensitivity search for the electric dipole moment of the neutron. Magnetic stability and control are achieved through a combination of passive shielding, provided by a magnetically shielded room (MSR), and a surrounding active field compensation system by an Active Magnetic Shield (AMS). The AMS is a feedback-controlled system of eight coils spanned on an irregular grid, designed to provide magnetic stability to the enclosed volume by actively suppressing external magnetic disturbances. It can compensate static and variable magnetic fields up to ± 50 μT (homogeneous components) and ± …

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Protective Row Covers For Management Of Flea Beetles In Organic Eggplant Production In The Southeastern Us, Elaine Losekamp, Robert Brockman, Viktor Halmos, Kathleen Fiske Pulliam, Ryan Kuesel, Ric Bessin, Delia Scott, Mark Williams, David Gonthier Apr 2026

Protective Row Covers For Management Of Flea Beetles In Organic Eggplant Production In The Southeastern Us, Elaine Losekamp, Robert Brockman, Viktor Halmos, Kathleen Fiske Pulliam, Ryan Kuesel, Ric Bessin, Delia Scott, Mark Williams, David Gonthier

Entomology Faculty Publications

Organic eggplant production in the United States is challenged by flea beetles, which stunt eggplant growth and reduce yield. Across four experiments between 2019 and 2024, we compared the effects of various pest management strategies on flea beetle abundance, damage, and marketable yield in eggplant production, focusing on row covers and organic insecticides in later years of the study. Treatments included fine-mesh row covers, organic insecticides, and untreated controls (all years); reflective plastic mulch (2019); various essential oils (2019–2020); conventional insecticide control (2019–2020); and spunbonded row covers (2019–2021). Low flea beetle pressure was observed in 2019 and 2020; consequently, experiments …

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Muscle Atrophy After Acl Reconstruction Involves Molecular Mechanisms Beyond Unloading, Alexander R. Keeble, Gonzalez Velez Sara, Nicholas T. Thomas, Allison M. Owen, Austin V. Stone, Darren L. Johnson, Julián Candia, Luigi Ferrucci, Marco Narici, Esther E. Dupont-Versteegden, Brian Noehren, Martino V. Franchi, Christopher S. Fry Apr 2026

Muscle Atrophy After Acl Reconstruction Involves Molecular Mechanisms Beyond Unloading, Alexander R. Keeble, Gonzalez Velez Sara, Nicholas T. Thomas, Allison M. Owen, Austin V. Stone, Darren L. Johnson, Julián Candia, Luigi Ferrucci, Marco Narici, Esther E. Dupont-Versteegden, Brian Noehren, Martino V. Franchi, Christopher S. Fry

Physiology Faculty Publications

Anterior cruciate ligament reconstruction (ACLR) leads to profound muscle atrophy and weakness that remain resistant to rehabilitation. Although early recovery typically involves a brief period of limb unloading, the degree to which disuse alone accounts for muscle pathology after ACLR remains unclear. Here, we leveraged publicly available RNA-seq datasets of muscle biopsies from vastus lateralis obtained 7 days after ACLR or 10 days after unilateral lower limb suspension (ULLS), each with matched control limbs, to directly compare disuse-driven and ACLR-specific early transcriptional responses. Despite similar periods of reduced loading, substantial transcriptomic divergence was identified using both intersection and interaction bioinformatic …

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The Association Between Apoe Ε4 Carrierships And The Detection Of Amyloid Positivity Using An Alzheimer's Disease Proteomic Blood Test In Asymptomatic Down Syndrome, Lubnaa Badriyyah Abdullah, Fan Zhang, Melissa Petersen, James Hall, Benjamin L. Handen, Mark Mapstone, Brad Christian, Elizabeth Head, Sigan Harley, Howard Andrews, Joseph H. Lee, Dana Tudorascu, Christy Hom, Shahid Zaman, Adam M. Brickman, Diana Rosas, Annie Cohen, Jordan P. Harp, Frederick Schmitt, Lauren Ptomey, Jeffrey M. Burns, Ira T. Lott, Florence Lai, Charles Laymon, Carlos Cruchaga, Sid O'Bryant, Beau M. Ances Apr 2026

The Association Between Apoe Ε4 Carrierships And The Detection Of Amyloid Positivity Using An Alzheimer's Disease Proteomic Blood Test In Asymptomatic Down Syndrome, Lubnaa Badriyyah Abdullah, Fan Zhang, Melissa Petersen, James Hall, Benjamin L. Handen, Mark Mapstone, Brad Christian, Elizabeth Head, Sigan Harley, Howard Andrews, Joseph H. Lee, Dana Tudorascu, Christy Hom, Shahid Zaman, Adam M. Brickman, Diana Rosas, Annie Cohen, Jordan P. Harp, Frederick Schmitt, Lauren Ptomey, Jeffrey M. Burns, Ira T. Lott, Florence Lai, Charles Laymon, Carlos Cruchaga, Sid O'Bryant, Beau M. Ances

Neurology Faculty Publications

INTRODUCTION: This study evaluates plasma-based proteomic profiles for predicting amyloid positivity in adults with Down syndrome (DS) and examines the impact of apolipoprotein E ε4 (APOE ε4) on test performance. METHODS: Cross-sectional data from 290 adults with DS were analyzed using single molecule array (SIMOA) technology to measure plasma amyloid beta (Aβ)42, Aβ40, neurofilament light chain (NfL), glial fibrillary acidic protein (GFAP), tau phosphorylated at threonine 181, and total tau. Amyloid burden was quantified using Pittsburgh Compound B and (18)F-florbetapir Aβ positron emission tomography. Support vector machine analyses were conducted with biomarkers as predictors and age, sex, and APOE ε4 …

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Novel Adult Learning-Based Curriculum For Pathology Residents, Hafsa Nebbache, Aaron Daniel Shmookler, Justin Rueckert, Daniel Crump, Sahar Nozad, Nathan Shelman, Derek B. Allison, Robert J. Mcdonald, C. Darrell Jennings, Leanna Brignola, Therese J. Bocklage, Janna H. Neltner Apr 2026

Novel Adult Learning-Based Curriculum For Pathology Residents, Hafsa Nebbache, Aaron Daniel Shmookler, Justin Rueckert, Daniel Crump, Sahar Nozad, Nathan Shelman, Derek B. Allison, Robert J. Mcdonald, C. Darrell Jennings, Leanna Brignola, Therese J. Bocklage, Janna H. Neltner

Markey Cancer Center Faculty Publications

Active learning forms the foundation of adult education methodology as it promotes durable retention of knowledge in accessible long-term memory. The most successful active learning strategy uses periodic testing, a memory recall, application, and consolidation activity termed “retrieval practice.” After reviewing adult learning science evidence, we created a two-year anatomic and clinical pathology residency core curriculum (Pathology Core Curriculum) in which we deployed six principles of adult learning, prioritizing retrieval practice as our key learning strategy. We hypothesized that the Pathology Core Curriculum would improve long-term knowledge retention which would correlate with progressively higher retrieval practice and resident in-service exam …

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Information-Content-Informed Kendall-Tau Correlation Methodology, Robert M. Flight, Praneeth S. Bhatt, Hunter N.B. Moseley Apr 2026

Information-Content-Informed Kendall-Tau Correlation Methodology, Robert M. Flight, Praneeth S. Bhatt, Hunter N.B. Moseley

Markey Cancer Center Faculty Publications

Background: Almost all correlation measures currently available are unable to directly handle missing values. Typically, missing values are either ignored completely by removing them or are imputed and used in the calculation of the correlation coefficient. In either case, the correlation value will be impacted based on the perspective that the missing data represents no useful information. However, missing values occur in real datasets for a variety of reasons. In metabolomics datasets a major reason for missing values is that a specific measurable phenomenon falls below the detection limits of the analytical instrumentation (left-censored values). These missing data are not …

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Mapping The Polar Neuro-Interactome Of Garcinia Mangostana Against The Ad-Pd-Als Nexus, Rahni Hossain, Sirirat Surinkaew, Pradoldej Sompol, Nasmah K. Bastaki, Rifat Jafrin, Nazim Sekeroglu, Jitbanjong Tangpong Apr 2026

Mapping The Polar Neuro-Interactome Of Garcinia Mangostana Against The Ad-Pd-Als Nexus, Rahni Hossain, Sirirat Surinkaew, Pradoldej Sompol, Nasmah K. Bastaki, Rifat Jafrin, Nazim Sekeroglu, Jitbanjong Tangpong

Markey Cancer Center Faculty Publications

Background/Objectives: Neurodegenerative diseases like Alzheimer’s, Parkinson’s, and Amyotrophic lateral sclerosis (ALS) share common molecular pathways, including neuroinflammation and oxidative stress, which complicate the effectiveness of single-target treatments. Garcinia mangostana L. (mangosteen) has shown neuroprotective properties, but previous studies focused on lipophilic xanthones, which have poor bioavailability and uncertain blood–brain barrier permeability. Methods: In the current study, polar metabolites from G. mangostana peel aqueous extract (GMPE) were assessed for potential multi-target interactions via UHPLC-QTOF-MS-based metabolomics, systems pharmacology, and molecular docking analysis. Further, in silico ADMET screening and network-based analyses assessed for overlap between GMPE compounds and genes associated with neurodegeneration (AD, …

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Role Of Succinate Dehydrogenase In Age-Related Th17 Inflammation, Evelyn Ocegueda, Gabrielle Chase, Michaella Niceforo, Aida Javidan, Lydia Gugliuzza, Jingting Yu, Rachel Y. Kang, Ava Lankowski, Olivia Stefanik, Kailey Leclerc, Yolander Valentine, Micah J. Drummond, Jude T. Deeney, Josephine S. Modica-Napolitano, Elizabeth A. Proctor, Hatice Hasturk, Barbara S. Nikolajczyk, Leena P. Bharath Apr 2026

Role Of Succinate Dehydrogenase In Age-Related Th17 Inflammation, Evelyn Ocegueda, Gabrielle Chase, Michaella Niceforo, Aida Javidan, Lydia Gugliuzza, Jingting Yu, Rachel Y. Kang, Ava Lankowski, Olivia Stefanik, Kailey Leclerc, Yolander Valentine, Micah J. Drummond, Jude T. Deeney, Josephine S. Modica-Napolitano, Elizabeth A. Proctor, Hatice Hasturk, Barbara S. Nikolajczyk, Leena P. Bharath

Markey Cancer Center Faculty Publications

Age-related cellular changes negatively impact CD4+ T cell function. Our prior work showed that mitochondrial complex II (succinate dehydrogenase [SDH]) expression was upregulated in T cells from older (O) adults (60–80 years old). T cells from older adults also produced higher amounts of cytokines generally considered proinflammatory, such as Th17 cytokines IL-17A/F and IL-21, and the Th-17-supportive cytokine IL-6, compared to T cells from younger (Y) adults (25–40 years old). The objective of our study is to evaluate whether hyperactivation of SDH is required for the induction of proinflammatory cytokines and the mechanistic link between SDH and Th17 cytokine …

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Systemic Consequences Of Chronic Ethanol Intake, Muni Swamy Ganjayi, Thomas A. Krauss, Gage E. Demster, Sehyung Park, Garrett B. Anspach, Sarah R. Anthony, Shaohua Wang, Michael Tranter, Robert N. Helsley, Cory W. Baumann Apr 2026

Systemic Consequences Of Chronic Ethanol Intake, Muni Swamy Ganjayi, Thomas A. Krauss, Gage E. Demster, Sehyung Park, Garrett B. Anspach, Sarah R. Anthony, Shaohua Wang, Michael Tranter, Robert N. Helsley, Cory W. Baumann

Markey Cancer Center Faculty Publications

Chronic ethanol (EtOH) consumption is a major contributor to multi-organ dysfunction, yet its systemic effects remain incompletely understood. To address this, we utilized a physiologically relevant long-term mouse model, administering 20% EtOH in drinking water for 60 weeks, to investigate the integrated consequences of chronic exposure. EtOH-consuming mice (0.4–0.5 mL/day) exhibited > 30% reductions in chow and fluid intake, resulting in a 12% decrease in total caloric intake compared to controls (p < 0.001). Body mass remained similar until Week 52, after which EtOH-treated mice had lower body mass due to reductions in both lean and fat mass (p ≤ 0.004). Functional assessments revealed impaired treadmill endurance (−17%) and grip strength (−11%) (p ≤ 0.037), while motor coordination remained unaffected (p = 0.203). Chronic EtOH exposure significantly altered gut microbiota composition, reducing Lactobacillus and enriching Faecalibaculum, Clostridium, and Bifidobacterium at the genus level. These changes were accompanied by marked depletion of short-chain fatty acids (p ≤ 0.05). Indirect markers of gut permeability (serum LPS & zonulin) and liver injury (serum ALT & AST, hepatic amyloid content) were elevated, alongside increased total cholesterol and > 62% upregulation of hepatic TNFα, IL-6 & serum amyloid A (p ≤ 0.046). EtOH also induced dyslipidemia and glucose intolerance (p ≤ 0.041), although transcriptomic changes in white adipose …

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National Trends And In-Hospital Outcomes Of Valve-In-Valve Transcatheter Aortic Valve Replacement With Cerebral Embolic Protection, Ammar A. Hasnie, Avneet Hans, Emad A. Chishti, Joseph Leith, Hannah Murphy, Alyssa H. Harris, Kory Heier, Kristen Mcquerry, Steve W. Leung, Islam Y. Elgendy Apr 2026

National Trends And In-Hospital Outcomes Of Valve-In-Valve Transcatheter Aortic Valve Replacement With Cerebral Embolic Protection, Ammar A. Hasnie, Avneet Hans, Emad A. Chishti, Joseph Leith, Hannah Murphy, Alyssa H. Harris, Kory Heier, Kristen Mcquerry, Steve W. Leung, Islam Y. Elgendy

Radiology Faculty Publications

No abstract provided.

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Plasmons Enable Ultralow Threshold Solid-State Triplet Fusion Upconversion With A 2d Sensitizer, Seamus S. Lowe, Satya P. Butler, John E. Anthony, Saien Xie, Barry P. Rand Apr 2026

Plasmons Enable Ultralow Threshold Solid-State Triplet Fusion Upconversion With A 2d Sensitizer, Seamus S. Lowe, Satya P. Butler, John E. Anthony, Saien Xie, Barry P. Rand

Chemistry Faculty Publications

Solid-state triplet–triplet annihilation (TTA) upconversion has significant potential for application in light harvesting, optoelectronic devices, and bioimaging. However, the high optical powers required to achieve efficient upconversion have inhibited its adoption. In this work, we demonstrate plasmon-enhanced near-infrared (NIR)-to-blue TTA upconversion in a monolayer WSe2/organic heterojunction. Under far-field excitation, the device reaches a threshold of 19 mW/cm2 and an external quantum efficiency (EQE) of 0.17% with an anti-Stokes shift of 1.1 eV. Plasmon excitation lowers the threshold to 0.9 mW/cm2 and improves the EQE to 3.6%. We attribute the plasmon enhancement to surface plasmon polariton (SPP) near-field enhancement and dark-exciton …

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Impact Of Age And Rurality On Colorectal Cancer Outcomes In The United States, Caitlyn Grunert, Meng Han Tsai, Charles R. Rogers, Sydney Howard, Rachel Hogg-Graham, Courtney Martin, Darwin Conwell, Adetunji T. Toriola, Avinash Bhakta, Justin Moore Apr 2026

Impact Of Age And Rurality On Colorectal Cancer Outcomes In The United States, Caitlyn Grunert, Meng Han Tsai, Charles R. Rogers, Sydney Howard, Rachel Hogg-Graham, Courtney Martin, Darwin Conwell, Adetunji T. Toriola, Avinash Bhakta, Justin Moore

Surgery Faculty Publications

Background: While overall colorectal cancer (CRC) rates have declined in the United States (U.S.), early-onset CRC (EO-CRC), diagnosed before age 50, has increased. Rural U.S. residents face higher CRC incidence than non-rural counterparts. We aimed to examine the relationship between age at diagnosis and EO-CRC outcomes and whether rurality modify these associations. Methods: We analyzed data from 835,907 patients aged 20–79 years in the 2006–2020 SEER Program. Rurality was defined using U.S. Department of Agriculture Rural–Urban Commuting Area (RUCA) codes. Multivariable logistic regression models were used to examine associations between age, rurality, and late-stage CRC diagnosis. Competing-risk regression models were …

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Surgical Nodal Sampling Established By Commission On Cancer Standard 5.8 Is Essential For Accurate Lung Cancer Staging, Raheem Bell, Amanda B. Francescatti, Daniel Boffa, Timothy W. Mullett, Matthew A. Facktor, Nirmal K. Veeramachaneni, Ryan C. Jacobs, Frank Schneider, Tina J. Hieken, David D. Odell, Ronald J. Weigel Apr 2026

Surgical Nodal Sampling Established By Commission On Cancer Standard 5.8 Is Essential For Accurate Lung Cancer Staging, Raheem Bell, Amanda B. Francescatti, Daniel Boffa, Timothy W. Mullett, Matthew A. Facktor, Nirmal K. Veeramachaneni, Ryan C. Jacobs, Frank Schneider, Tina J. Hieken, David D. Odell, Ronald J. Weigel

Surgery Faculty Publications

Objective Accurate mediastinal staging is critical for the effective treatment of non–small cell lung cancer because lymph node involvement significantly influences prognosis and therapeutic decisions. We sought to evaluate the diagnostic accuracy, limitations, and complementary roles of endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA), cervical mediastinoscopy, and surgical lymph node sampling in mediastinal staging of non–small cell lung cancer. Methods A systematized literature review was performed using PubMed and national guideline repositories. Studies were included if they reported or provided sufficient data to calculate the negative predictive value (NPV) for EBUS-TBNA, mediastinoscopy, or surgical lymph node sampling. Data were synthesized qualitatively …

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A Pathogenic Tau Mutation Drives Autophagy-Lysosome Dysfunction That Limits Tau Degradation In A Model Of Frontotemporal Dementia, Farzaneh S. Mirfakhar, Jacob A. Marsh, Chihiro Sato, Kylie J. Schache, Miguel A. Minaya, Roland E. Dolle, Stephen C. Pak, Gary A. Silverman, David H. Perlmutter, Shannon L. Macauley, Celeste M. Karch Mar 2026

A Pathogenic Tau Mutation Drives Autophagy-Lysosome Dysfunction That Limits Tau Degradation In A Model Of Frontotemporal Dementia, Farzaneh S. Mirfakhar, Jacob A. Marsh, Chihiro Sato, Kylie J. Schache, Miguel A. Minaya, Roland E. Dolle, Stephen C. Pak, Gary A. Silverman, David H. Perlmutter, Shannon L. Macauley, Celeste M. Karch

Physiology Faculty Publications

Tau accumulates in a group of neurodegenerative diseases known as tauopathies. A prevailing hypothesis has been that Tau degradation is impaired due to an age-related imbalance in the autophagy-lysosome pathway, but whether these defects are a cause or consequence of Tau accumulation remains unclear. Here we show that a disease-causing mutation in the MAPT gene, which encodes Tau, p.R406W, is sufficient to disrupt multiple steps of the autophagy-lysosome pathway in human neurons. Using Airyscan super-resolution imaging, we find that mutant Tau neurons accumulate Tau and phosphorylated Tau in dysfunctional lysosomes, exhibit reduced lysosome motility, impaired fusion of autophagosomes and lysosomes, …

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Oral Health In People With Schizophrenia, Leire Urien, Ainara Arnaiz, Xabier Marichalar-Mendia, Unax Lertxundi, Jose De Leon, Agate Txurruka, Nerea Jauregizar, Teresa Morera-Herreras Mar 2026

Oral Health In People With Schizophrenia, Leire Urien, Ainara Arnaiz, Xabier Marichalar-Mendia, Unax Lertxundi, Jose De Leon, Agate Txurruka, Nerea Jauregizar, Teresa Morera-Herreras

Psychiatry Faculty Publications

Aim This study aimed to assess the oral health status of individuals with schizophrenia and explore its association with behavioural and pharmacological factors, with particular focus on long-term antipsychotic treatment and cumulative anticholinergic burden. Methods A total of 153 adults with schizophrenia (18–65 years) from the Mental Health Network of Bizkaia (Spain), all under antipsychotic treatment for ≥12 months, were evaluated and compared with 153 controls from the general population. Data on socio-demographic variables, tobacco use and oral hygiene habits were collected. Oral health was assessed using the Decayed, Missing and Filled Teeth (DMFT) index and the Community Periodontal Index …

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Generative Models And Synthetic Data In Clinical Prediction Models, Anthony A. Mangino, Taha Ahmed, Vincent L. Sorrell Mar 2026

Generative Models And Synthetic Data In Clinical Prediction Models, Anthony A. Mangino, Taha Ahmed, Vincent L. Sorrell

Radiology Faculty Publications

Introduction: Reproducibility, consistency, and transparency are essential to responsible and ethical scientific inquiry, though practices supporting these qualities are often neglected. However, in many cases data are confidential or otherwise unable to be shared publicly. This tutorial describes a method utilizing generative adversarial networks (GANs) to create synthetic data that are sufficiently similar to the original dataset in such cases where the source data cannot be shared or where the source data are too sparse as to internally validate results. Methods: Utilizing an exemplar study that aimed to create a clinical prediction model employing a novel echocardiographic measurement to differentiate …

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The Supreme Court's Goldilocks: Why The Major Questions Doctrine Is The Ideal Compromise Between Two Unattractive Extremes, Bradley P. Simpson Mar 2026

The Supreme Court's Goldilocks: Why The Major Questions Doctrine Is The Ideal Compromise Between Two Unattractive Extremes, Bradley P. Simpson

Kentucky Law Journal

No abstract provided.

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Exposing Car Dealerships' Final Hidden Sales Con: A Call For The Disclosure Of Interest Rate Markups When "Helping" Buyers With Indirect Financing, John C. Simms Mar 2026

Exposing Car Dealerships' Final Hidden Sales Con: A Call For The Disclosure Of Interest Rate Markups When "Helping" Buyers With Indirect Financing, John C. Simms

Kentucky Law Journal

No abstract provided.

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Congress's Mistaken Ip Power And Our Hybrid Constitutionalism, Barry P. Mcdonald Mar 2026

Congress's Mistaken Ip Power And Our Hybrid Constitutionalism, Barry P. Mcdonald

Kentucky Law Journal

No abstract provided.

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The Brave New World Of Judicial Elections, Charles Gardner Geyh Mar 2026

The Brave New World Of Judicial Elections, Charles Gardner Geyh

Kentucky Law Journal

No abstract provided.

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A Tale Of Two Landlords, Christopher J. Ryan Jr. Mar 2026

A Tale Of Two Landlords, Christopher J. Ryan Jr.

Kentucky Law Journal

No abstract provided.

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Table Of Contents For Volume 114, Issue 1, Kentucky Law Journal Mar 2026

Table Of Contents For Volume 114, Issue 1, Kentucky Law Journal

Kentucky Law Journal

No abstract provided.

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The Case For Lgbtq+ Adoption Rights In The Post-Roe Era, Tate Craft Mar 2026

The Case For Lgbtq+ Adoption Rights In The Post-Roe Era, Tate Craft

Kentucky Law Journal

No abstract provided.

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Domestic Guestworkers: A Call To End The H-2b Program And Empower American Workers, Preston Huennekens Mar 2026

Domestic Guestworkers: A Call To End The H-2b Program And Empower American Workers, Preston Huennekens

Kentucky Law Journal

No abstract provided.

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Impeachment Can Be Based On Non-Criminal Misconduct: Corpus-Linguistic And Historical Evidence, Clark D. Cunningham, Ute Römer-Barron Mar 2026

Impeachment Can Be Based On Non-Criminal Misconduct: Corpus-Linguistic And Historical Evidence, Clark D. Cunningham, Ute Römer-Barron

Kentucky Law Journal

No abstract provided.

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Party Over Country: The Inability For Congress To Check The Executive, Jordin A. Dickerson Mar 2026

Party Over Country: The Inability For Congress To Check The Executive, Jordin A. Dickerson

Kentucky Law Journal

No abstract provided.

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Federal Prosecution In The Shadows Of Constitutional Immunity, J. Richard Broughton Mar 2026

Federal Prosecution In The Shadows Of Constitutional Immunity, J. Richard Broughton

Kentucky Law Journal

No abstract provided.

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President Biden's Influence On The Use Of Executive Privilege, Mitchel A. Sollenberger, Mark J. Rozell Mar 2026

President Biden's Influence On The Use Of Executive Privilege, Mitchel A. Sollenberger, Mark J. Rozell

Kentucky Law Journal

No abstract provided.

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