Digital Commons Network^™

Jwst Spectroscopic Insights Into The Diversity Of Galaxies In The First 500 Myr, Guido Roberts-Borsani, Pascal A. Oesch, Richard Ellis, Andrea Weibel, Emma Giovinazzo, Rychard Bouwens, Pratika Dayal, Adriano Fontana, Kasper E. Heintz, Jorryt Matthee, Romain A. Meyer, Laura Pentericci, Alice Shapley, Sandro Tacchella, Tommaso Treu, Fabian Walter, Hakim Atek, Sownak Bose, Marco Castellano, Yoshinobu Fudamoto, Takahiro Morishita, Rohan P. Naidu, Ryan L. Sanders, Arjen Van Der Wel

Physics and Astronomy Faculty Publications

We investigate the nature and spectroscopic diversity of early galaxies from a sample of 41 sources at (Formula presented) with James Webb Space Telescope (JWST)/NIRSpec prism observations. We compare the properties of strong ultraviolet (UV) line emitters, traced by intense C iv emission, with those of more ‘typical’ sources with weak or undetected C iv. The more typical (or ‘C iv-weak’) sources reveal significant scatter in their C iii] line strengths, UV continuum slopes, and physical sizes, spanning C iii] equivalent widths (EWs) of (Formula presented) 1–51 Å, UV slopes of (Formula presented) to (Formula presented), and half-light radii of …

Probing Late-Stage Hadronic Interactions At High Baryon Density Via K⁎0 Production In The Rhic Beam Energy Scan Program, B. E. Aboona, J. Adam, G. Agakishiev, I. Aggarwal, M. M. Aggarwal, Z. Ahammed, A. Aitbayev, I. Alekseev, E. Alpatov, A. K. Alshammri, A. Aparin, S. Aslam, J. Atchison, G. S. Averichev, V. Bairathi, X. Bao, P. Barik, K. Barish, S. Behera, P. Bhagat, A. Bhasin, S. Bhatta, I. G. Bordyuzhin, J. D. Brandenburg, A. V. Brandin, C. Broodo, X. Z. Cai, H. Caines, M. Calderón De La Barca Sánchez, D. Cebra, J. Ceska

Physics and Astronomy Faculty Publications

A precision measurement of the K ^⁎0 meson yield is reported in Au+Au collisions at s_NN=7.7,11.5,14.6,19.6, and 27 GeV using the high-statistics data sample collected by the STAR experiment during the Beam Energy Scan II (BES-II) program at RHIC. The transeverse momentum ( p_T )-integrated yield ratios (K^*0+K^*0‾)/(K⁺+K⁻) in central collisions show a suppression relative to peripheral collisions at the (1.7–3.6) σ level, while a thermal model without final-stage rescattering overpredicts this ratio with a deviation of (6.9–8.2) σ . These results indicate a loss of the measured K …

Monazite And Xenotime U-Pb Geochronology And Thermometry Of The Blue Ridge And Inner Piedmont Of North Carolina, Nicholas E. Powell, J. Ryan Thigpen, Brandon M. Spencer, Arthur J. Merschat, David P. Moecher, Calvin A. Mako, Robert D. Hatcher, Harold H. Stowell, Andrew Kylander-Clark

Earth and Environmental Sciences Faculty Publications

The southern Appalachian orogen preserves a complex distribution of metamorphism and deformation varying in timing, magnitude, and spatial extent. These complexities give rise to disparate interpretations for southern Appalachian tectonic evolution, which complicates the testing and interpretation of tectonic models in this system. New monazite (Mnz) and xenotime (Xtm) laser ablation split stream (LASS) analyses alongside Mnz-Xtm thermometry in the orogenic core in the eastern Blue Ridge (EBR), western Inner Piedmont (WIP), and Cat Square terranes (CST) of North Carolina yield new constraints that define distinct pro- and retrograde metamorphic events. The EBR preserves two prograde thermal events: the Taconic …

Election Fraud In The American Mind, Mitchell Brown, Spencer Goidel, Soren Jordan, Bridgett A. King, Isaac Westfall, Ryan Williamson

Political Science Faculty Publications

Objective: Disputes over election fraud have become a defining feature of contemporary American politics, yet it remains unclear whether partisans are disagreeing about the same underlying phenomenon. This article examines how Americans understand and interpret the phrase “election fraud” and whether partisan divisions reflect differences in concern about fraud or differences in what the term itself is taken to mean. Methods: We use novel survey questions included in our team's module of the 2024 Cooperative Election Study (N = 1000). An open-ended question captures respondents’ own top-of-mind associations with the phrase “election fraud,” while a closed-ended item asks respondents to …

Building Resilience When Disaster Strikes, Anna G. Kalema, Felipe González-Seguel, Louisa A. Summers, Esther E. Dupont-Versteegden, Ashley A. Montgomery-Yates, Kirby P. Mayer

Physiology Faculty Publications

No abstract provided.

S100a4-Lineage Cells Contribute Modestly To Angiotensin Ii-Mediated Thoracic Aortic Aneurysms Through Angiotensin Ii Type 1a Receptor In Mice, Sohei Ito, Jeff Z. Chen, Deborah A. Howatt, Jessica J. Moorleghen, Hong S. Lu, Alan Daugherty, Hisashi Sawada

Physiology Faculty Publications

Angiotensin II (AngII) exerts a critical role in thoracic aortic aneurysm (TAA) formation via AngII type 1a receptor (AT1aR). However, the principal cell type mediating this process remains unclear. Our previous study demonstrated that S100A4-lineage cells are present in the aortic wall and involved in AngII-induced vascular remodeling. In the present study, we investigated whether S100A4-lineage cells contribute to AngII-mediated TAA formation through AT1aR. Proteomic, bulk RNA sequencing, and single-cell RNA sequencing data were analyzed to assess changes in S100A4 abundance in response to AngII infusion. Lineage tracing was performed to track S100A4-lineage cells during AngII-mediated TAA formation. Either saline …

A Two-Stage Screening Approach Integrated With Gwas For Rare Phenotypes Such As Spontaneous Haploid Genome Doubling In Maize, Mercy Fakude, Tyler L. Foster, Yu Ru Chen, Ann Murithi, Siddique Imran Aboobucker, Ursula Karoline Frei, Philip M. Dixon, Thomas Lübberstedt

Plant and Soil Sciences Faculty Publications

Spontaneous haploid genome doubling (SHGD) is a valuable trait in maize breeding, enabling the development of doubled haploid (DH) lines without chemical chromosome doubling. However, SHGD is a rare phenotype, expressed in only a small fraction of maize germplasm, making its identification resource-intensive. This study evaluated the efficiency of a two-stage field screening approach designed to identify maize genotypes with high haploid male fertility (HMF), a key indicator of SHGD potential. Simulation analyses showed that evaluating 50 haploid plants per genotype, combined with a 25% HMF threshold, provides an optimal balance between detection accuracy and resource efficiency. Across three growing …

Population Genomics Of A Cosmopolitan Weed Provides Insights Into Its Local Adaptation And Recent Demographic History, Marilia Souza Lucas, Christoph Rosche, Isabell Hensen, Stefan G. Michalski, Dávid U. Nagy, Diana Gamba, Renske E. Onstein, Karime Abidkulova, Mohammad Al-Gharaibeh, Ali A. Al-Namazi, Sirwan Babaei, Fernando Bastida, Caio Brunharo, Aurélien Caillon, Ragan M. Callaway, Sam St Clair, Darron A. Cullen, Ryan Donnelly, Alyson Ennis, David J. Ensing, Özkan Eren, Andrey Erst, Rita Filep, Luke Flory, Lauren J. Frazee, Yusufjon Gafforov, Fidji Gendron, Zigmantas Gudžinskas, Christopher Matt Guilliams, Avni Hajdari, Jian Hua Hao, Erin Haramoto

Plant and Soil Sciences Faculty Publications

Invasive plant species present a growing ecological and economic challenge, and often adapt rapidly to their novel environments through complex demographic and evolutionary processes. Invasion genomics offers powerful tools to disentangle these processes, but most studies rely on geographically narrow sampling across native and non-native ranges. Erigeron canadensis is a cosmopolitan weed native to North America that has successfully invaded diverse climates worldwide. We used double-digest restriction site-associated DNA sequencing (ddRADseq) to investigate the genetic diversity and structure of 280 E. canadensis populations across the Northern Hemisphere. We found that native and non-native populations maintained comparable genetic diversity. Population structure …

Seed Dormancy Cycling, Jingshi Yang, Yan Luo, Jerry M. Baskin, Carol C. Baskin, Andreas Prinzing, Luping Liu, Chaohan Xu, Keliang Zhang

Plant and Soil Sciences Faculty Publications

Timing of seed germination is critical for survival of annual plants in seasonal climates. We tested the hypothesis that seeds of the winter annual species Cardamine impatiens (Brassicaceae) “track” their thermal environment and synchronize germination with favorable growth conditions. We predicted that seeds buried in the field from maturity to autumn germinate best at autumn temperatures, while those buried from maturity to spring germinate best in early spring. We monitored seasonal changes in germinability by exhuming field-buried seeds monthly for 30 months and incubating them under laboratory conditions. The effects of temperature on the transition of dormancy status also were …

Triacontanol Boosts Soybean Nodulation Via Gmhsp26-Mediated Antioxidant Enhancement, Bingjie Niu, Minglei Cheng, Xudong Lu, Lili Sun, Shuang Lu, Jinke Guo, Hongyan Zhu, Lixiang Wang

Plant and Soil Sciences Faculty Publications

Soybean (Glycine max (L.) Merr.) is a globally crucial food crop and a model plant for studying symbiotic nitrogen fixation in legumes. Triacontanol (TRIA) is a natural plant growth regulator that enhances photosynthetic efficiency, stress tolerance, antioxidant enzyme activities and yield in crops. However, its regulatory role in nodulation and nitrogen fixation in legumes remains unclear. In this study, soybean seedlings inoculated with Bradyrhizobium japonicum strain USDA110 were treated with different concentrations of TRIA (0, 0.33, 0.5, 1 and 2 μg/mL). Then, oxidative stress indicators and comparative transcriptomic analysis were performed to check the oxidative status and screen the candidate …

A Study In Vigibase Of Clozapine Fatal Outcomes In 7874 Middle-Aged Versus 4380 Young Adults, Carlos De Las Cuevas, Emilio J. Sanz, Jose De Leon

Psychiatry Faculty Publications

Fatal outcomes associated with clozapine adverse drug reactions (ADRs) were studied for over/underrepresentation in middle-aged (45–64 years) versus young adult patients (18–44 years). These fatal outcomes were obtained from the worldwide pharmacovigilance database (VigiBase) from inception to January 15, 2023, including 7874 cases of middle-aged adults versus 4380 young adult controls. Fatal outcomes of clozapine ADRs were ranked by frequency; over/underrepresentation was determined by comparison with controls using univariate odds ratios (OR), their 95 % confidence intervals (CIs) and adjusted ORs after adjusting for major confounders. Overrepresentation (12.5 % vs. 5.6 % with an adjusted OR = 2.41; CI: 2.08–2.78) …

Case Report: Gangrene After One Dose Of Investigational Stannic Pentetate Radiopharmaceutical, Zin W. Myint, Riham H. El Khouli, Bryan P. Lemieux, Charles A. Kunos

Radiology Faculty Publications

Introduction – Bone-seeking radiopharmaceuticals are the treatment of choice with clinical benefits for patients with extensive skeletal metastases, but they can also cause serious radiation-related adverse events (rrAEs). Management of rare and severe radiopharmaceutical rrAEs remains challenging because of incomplete knowledge of their natural history and pathogenetic mechanisms. We report a case of unlikely related gangrene following a protracted hospitalization after one dose of investigational [117mSn]tin-117m-diethylenetriaminepentaacetic acid (Sn-117m-DTPA) for treatment of extensive skeletal metastases from castration-resistant prostate cancer (mCRPC). Case presentation – An 80-year-old man with innumerable painful skeletal metastases from mCRPC developed anorexia and bilateral ankle edema with serous-draining …

Hybrid Fabrication Of An Electrochemical Electrode Via Inkjet Printing On 3d-Printed Substrates, Md Tawabur Rahman, Jessica Bone, Thomas J. Roussel, Judith L. Jenkins, Aron J. Huckaba

Chemistry Faculty Publications

Combinations of additive manufacturing methods such as inkjet printing and various 3D printing techniques have led to advances in customizable electronic devices by reducing the need for the complex assembly of individually fabricated components. Such combinations are particularly attractive for the fabrication of electrochemical sensing platforms, where the sizes and spatial configurations of electrodes enable (or limit) the sensitivity of the sensors. However, to realize the potential of the combined fabrication methods, the parameters of each printing technique must be mutually compatible. For instance, electrochemical sensing assemblies consisting of inkjet-printed metals on 3D-printed plastics require post-processing steps that convert nanoparticular …

Student Perspectives On Grading In Higher Education Stem Courses, Christopher Sean Burns, Daniela D.S. Digiacomo, Jennifer Pusateri, Katherine Ritchie, Christine Wusylko

Information Science Faculty Publications

Purpose

Despite a growing awareness of instructional practices that support student learning and well-being, higher education classrooms tend to still be dominated by the use of rigid approaches to assessment and course design. This study aims to understand the experiences of students in courses that implement a universal design for learning (UDL) pedagogical approach and an ungrading assessment approach. Design/methodology/approach

Leveraging a qualitative methodological approach, authors interviewed 13 graduate students in two library and information science technology courses and 11 undergraduate students in a computer science course in discrete mathematics about their experiences with ungrading within the context of UDL-designed …

The Impact Of Seyfert Jets On Galaxy Evolution Across Major Scaling Relations, Julianne Goddard, Isaac Shlosman, Emilio Romano-Diaz

Physics and Astronomy Faculty Publications

We analyze a suite of high-resolution cosmological zoom-in simulations of jetted Seyfert galaxies over z < ∼10 projected on the major scaling relations, comparing trajectories of “normal” versus jet-hosting galaxies. Models include thermal and mechanical jet feedback launched from supermassive black holes (SMBHs) seeded at z ∼ 9.1 and z ∼ 3.7 with M_• ∼ 10⁶ M_⊙ in galaxies within dark matter halos of (Formula presented) logMhalo/M⊙∼11.8 at z = 0. A single parameter, the SMBH accretion efficiency, has been varied, resulting in L_jet ∼ 10⁴⁰⁻⁴² erg s⁻¹, and SMBH accretion rates range between ∼0.2 and 10⁻⁴ of the Eddington rate. We find that jet feedback (1) suppresses central star formation rates (SFRs), redistributes gas to larger radii, (2) generates long-lived expanding shocks that couple to the interstellar medium and circumgalactic …

First Covid-19 Vaccination Rates Among Pregnant Tennessee Women By Month Of Conception And Urbanization Level: March 2021 – November 2021, Claudia Valenzuela, Anne K. Driscoll, Elizabeth Harvey, Heather Wingate

Journal of Appalachian Health

Introduction: Throughout the pandemic, COVID-19 vaccination coverage was lower for the general population living in rural counties than in urban counties. In Tennessee (TN), COVID-19 vaccinations became available to pregnant women in March 2021. Little is known about rates of COVID-19 vaccination in pregnancy during the pandemic, or whether these rates changed or differed by urbanization level.

Purpose: The purpose of this study is to describe COVID-19 vaccination rates among pregnant women in TN by month of conception and urbanization level.

Methods: COVID-19 vaccination data from the TN Immunization Information System and the TN Surveillance for Emerging Threats to Mothers …

Evaluating The Feasibility And Preliminary Effectiveness Of A Tailored Diabetes Education Program For Rural Residents, Brittany L. Smalls, Oluwatosin Leshi, Suraksha Khanal, Grejika E. Abram-Erby

Journal of Appalachian Health

Introduction: Diabetes is a top ten Rural Healthy People 2030 priority for health improvement among rural Americans. Socioeconomic, environmental, geographic and political barriers contribute to the type 2 diabetes (T2D) prevalence and its disparate impact in rural communities. However, promoting proper self-care behaviors via self-management education can help people with diabetes better manage their condition.

Purpose: To account for the social environmental factors that affect rural residents, a tailored diabetes education program was developed, and the program’s effectiveness in improving diabetes knowledge and T2D-related health outcomes was assessed.

Methods: Using data collected from Appalachian Kentucky residents enrolled in a six-week, …

Rural Community Perspectives On Hurricane Helene In Western North Carolina, Jennifer A. Horney, Lilly Moreau, Search Wnc

Journal of Appalachian Health

Introduction: After making landfall on the Florida Gulf Coast in September 2024, Hurricane Helene impacted Western North Carolina (WNC) with historic flooding, landslides, and hurricane-force winds. More than 100 deaths in the region were attributed to the storm’s direct impacts.

Purpose: The purpose of this study was to assess community perspectives of long-term recovery in Mitchell and Yancey Counties, two rural WNC counties severely impacted by Hurricane Helene.

Methods: A 14-question interview guide was developed based on prior disaster research and the community engagement work of Sustaining Essential and Rural Community Healthcare (SEARCH). Questions covered post-Helene experiences related to access …

Exploring Systemic Challenges In The Western North Carolina Dental Safety Net: A Qualitative Analysis, Blaire Mirmow, Bill Milner, Nadia Laniado

Journal of Appalachian Health

Introduction: Despite statewide growth, rural communities in Western North Carolina (WNC) face persistent barriers to oral health care driven by chronic dental workforce shortages and systemic geographic disparities. Within this Appalachian region, the dental safety net serves as a vital yet strained support system, struggling with limited financial resources and a lack of provider participation that leaves many underserved populations without essential oral health services.

Purpose: This study aims to explore the experiences of individuals working within the WNC dental safety net to identify barriers and strategies required to strengthen the delivery of oral health care in high-need rural settings. …

Infective Endocarditis Hospitalizations In Kentucky, 2008-2018: Spatial And Temporal Trends, Meera Marji, Steve Browning, W. Jay Christian, Richard Charnigo, Steve W. Leung, Anna Kucharska-Newton

Journal of Appalachian Health

Introduction: Infective endocarditis (IE) hospitalization rates have increased significantly in the last decade, primarily due to the opioid epidemic. In 2016, Kentucky (KY) ranked among the top ten states for opioid-related overdose deaths, but limited data exist on IE trends in KY.

Purpose: This study seeks to examine county-level spatial and temporal trends in IE hospitalization rates in KY.

Methods: Hospital inpatient discharge data from 2008–2018 for KY residents aged 18 and older were analyzed. IE admissions and drug use status were identified using ICD-9 & 10 diagnosis codes. U.S. Census data calculated yearly IE hospitalization rates per 100,000 residents. …

The Effects Of Hurricane Helene On Mental Health And Physical Activity, Hunter Smathers, Robyn York, Jarrett Walbolt

Journal of Appalachian Health

Introduction: Hurricane Helene brought widespread damage to Southern Appalachia, disrupting utilities, health care, and recreation. While natural disasters are linked to declines in mental and physical health, few studies have examined their effects on distinct types of physical activity (PA).

Purpose: This study evaluated the effects of Hurricane Helene on perceived stress, depressive symptoms, post-traumatic stress disorder (PTSD) symptomology, and intentional (exercise for health benefits) and incidental (physical labor or transportation) PA. Evacuation status influence was also explored.

Methods: Twenty participants completed assessments four weeks before (BASE), immediately after (0POST), and four weeks after landfall (4POST). Measures included the Perceived …

Starting With Story, Not Symptom: Narrative Collapse And Cultural Repair In Appalachia, Wayne Coombs Ph.D.

Journal of Appalachian Health

Appalachia’s opioid crisis reflects uneven burdens, especially in distressed coalfield counties, and it cannot be solved by symptom tracking alone. This commentary argues for a narrative shift, starting with story and cultural repair alongside clinical care. Narrative collapse is defined here as the loss of shared, dependable public meaning across groups, not the absence of storytelling in families, churches, and recovery circles. Trauma science suggests that chronic threat reshapes nervous systems across generations, making safety a prerequisite for renewed trust. Drawing on narrative identity research, the piece proposes peer story work as infrastructure that can reduce shame, support treatment engagement, …

Consistent Gas-Phase Temperatures And Metallicities From Uv And Optical Nebular Emission, Erin Huntzinger, Yuguang Chen, Tucker Jones, Ryan Sanders, Peter Senchyna, Daniel Stark, Fabio Bresolin, Stephane Charlot, Jacopo Chevallard

Physics and Astronomy Faculty Publications

The rest-frame ultraviolet (UV) spectra of star-forming galaxies are increasingly important as they become one of the primary windows to probe the physical properties of cosmic dawn (z > 8) galaxies with the James Webb Space Telescope. However, the systematic discrepancies between UV and optical gas-phase metallicity measurements remain poorly understood in the local universe, partly due to challenges in achieving precise comparisons between UV and optical spectra for the same objects. In this work, we introduce a novel method that leverages the He II λ1640 and He II λ4686 nebular emission lines to achieve accurate aperture and reddening corrections between …

Gender And Power Dynamics In Three Types Of Injection Partnerships Among Young Women In Rural Appalachia, Cheyenne R. Wagi, Jaelyn Murphy, Madison N. Enderle, Hannah Piscalko, Kathleen L. Egan, Christina S. Meade, Bridget Freisthler, April M. Young, Angela Estadt, Kathryn E. Lancaster

Epidemiology and Environmental Health Faculty Publications

Background: Young women who inject drugs (YWID) face heightened risks for HIV, hepatitis C, and overdose that are shaped by the relational contexts in which they inject. Injection partnerships, defined as dyadic relationships between people who inject together, remain understudied beyond male–female intimate pairs. Methods: We conducted 26 semi-structured interviews with YWID (ages 18–35) in rural Appalachian Ohio to explore dynamics within three partnerships types: dual partnerships with male intimate partners, family partnerships, and friend partnerships, with attention to female peer partnerships as a distinct subset. Guided by the Theory of Gender and Power and Bourdieu’s concept of cultural capital, …

Environmental Exposure And Respiratory Health In Industrial Gulf Coast Communities, Ayodeji Iyanda, Chiung Fang Chang, Jennifer Erdely, Genny Carrillo, Tianjun Lu, Christopher Jones, Hilton Kelley, Daikwon Han, Xiao Huang, Yongmei Lu

Epidemiology and Environmental Health Faculty Publications

Background: Industrialized communities along the U.S. Gulf Coast face persistent respiratory health inequities that are shaped by cumulative environmental exposures and social vulnerability. This study examined how residential proximity to multiple pollution sources interacts with sociodemographic and behavioral factors to influence respiratory outcomes in two industrial cities in Southeast Texas. Methods: A cross-sectional mixed methods design integrated survey data from 2,965 adult residents with 13 qualitative interviews. Multivariable logistic regression models estimated associations between self-reported residential proximity to pollution sources and physician-diagnosed asthma, chronic obstructive pulmonary disease (COPD), and other lung diseases, and included interaction terms to assess effect modification …

Constraining The Subgalactic Relationship Between Star Formation And The Hot Interstellar Medium In Ngc 4254, Erik B. Monson, Bret D. Lehmer, Amirnezam Amiri, Karina Barboza, Ashley T. Barnes, Antara R. Basu-Zych, Daniel A. Dale, Sanskriti Das, Simthembile Dlamini, Simon Glover, Kathryn Kreckel, Laura A. Lopez, Sebastian Lopez, Smita Mathur, Hsi An Pan, Jennifer A. Rodriguez, Karin Sandstrom, Sumit K. Sarbadhicary, Jiayi Sun, Thomas G. Williams

Physics and Astronomy Faculty Publications

We investigate the relationship between star formation and X-ray emission from the hot interstellar medium (ISM) on ∼kiloparsec scales in NGC 4254 (M99) by combining spatially resolved star formation histories (SFHs) and Bayesian X-ray spectral fitting. We measure subgalactic star formation rates (SFR) by modeling spectrophotometric UV-IR data with flexible SFHs, and we produce point-source-subtracted maps of the diffuse X-ray emission using Chandra data. We extract and fit the spectra of five regions selected by their SFR density Σ_SFR, deriving hot gas luminosities and plasma temperatures. We examine the subgalactic kT–Σ_SFR and L_X^gas − Σ …

Social Determinants Of Sleep Health Inequities Among Rural Appalachian Adults, Mairead E. Moloney, Emily Slade, Joon Chung, Maliha Mehnaz Mitu, Michael A. Grandner, Daniela C. Moga

Sociology Faculty Publications

No abstract provided.

Patients' Attitudes Towards Deprescribing And Associations With Patient-Related Factors Across Two Hospital Settings, Louise Westberg Strejby Christensen, Iman El Gamah, Amina Osman Ismail Barre, Daniela Claudia Moga, Anissa Aharaz, Olivia Bornæs, Rikke Lundsgaard Nielsen, Aino Leegaard Andersen, Esben Iversen, Kim Peder Dalhoff, Ove Andersen, Helle Gybel Juul-Larsen, Morten Baltzer Houlind

Epidemiology and Environmental Health Faculty Publications

Medication deprescribing is a targeted strategy to reduce inappropriate polypharmacy. Patients in primary care settings have reported high willingness to discontinue medications, but this phenomenon is less well studied in hospital settings. In this explorative post hoc analysis of two previously described clinical trials, we assessed patients' attitudes towards deprescribing in two hospital-based cohorts: acutely admitted older medical patients (≥ 65 years) in the emergency department at Copenhagen University Hospital Hvidovre (October 2018–April 2021) and multimorbid patients (≥ 18 years) referred to an outpatient clinic at Copenhagen University Hospital Amager (March 2019–December 2019). Among 104 and 72 patients in each …

Multi-Jurisdictional Hazard Mitigation Plan For Landslides For The Kentucky River Area Development District, Kentucky, Hudson J. Koch, Matt M. Crawford, Jason M. Dortch

Contract Reports--KGS

Landslides are a widespread and complex geologic hazard that affects people and infrastructure. The Kentucky River Area Development District, Kentucky, sustains relatively high landslide activity that impacts several municipalities in eastern Kentucky. This hazard mitigation planning project outlines landslide hazard and risk assessments for the Kentucky River Area Development District, with information needed for each community in the region to develop mitigation strategies that will support infrastructure and development needs, land-use planning, situational awareness, and response and recovery actions for the communities.

Avoiding Misleading Estimates Of Among-Individual Variance Caused By Non-Random Sampling Of Individuals In A Changeable Environment, Denis Réale, Hassen Allegue, Yimen G. Araya-Ajoy, Ned A. Dochtermann, Shinichi Nakagawa, Joel L. Pick, Holger Schielzeth, David F. Westneat, Niels J. Dingemanse

Biology Faculty Publications

Animal ecologists frequently quantify variance in hierarchically structured traits in wild populations. Importantly, phenotypic plasticity within the period of measurement can modify the trait of interest in response to various unmeasured, temporally or spatially changeable, environmental conditions. Non-random sampling among units of the random effect (e.g. individuals) regarding the environment at issue may lead to estimates of the variance among ((Formula presented.)) or within ((Formula presented.)) such units that conflate several types of processes. This mixing of underlying biology can affect interpretations of the random effect variance. Here, we explore the conditions leading to this situation and assess potential solutions …