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Missed Clinic Appointments For Human Papillomavirus-Related Oropharyngeal Cancer, John M. Vieth, Anthony A. Mangino, Melina J. Windon, Joseph Valentino Jun 2026

Missed Clinic Appointments For Human Papillomavirus-Related Oropharyngeal Cancer, John M. Vieth, Anthony A. Mangino, Melina J. Windon, Joseph Valentino

Biostatistics Faculty Publications

Background: Missing appointments delay treatment affecting patient outcomes and healthcare resource utilization. Adherence to scheduled appointments has not been studied in patients with HPV-related oropharyngeal squamous cell carcinoma (HPV-OPSCC). Methods: We collected data from 36,690,000 scheduled medical outpatient encounters at the University of Kentucky Health Care from 2012 to 2021. A total of 36,579 of these encounters were from 334 patients with HPV-OPSCC. We performed regression analysis of no-show appointments by demographics, tumor characteristics, and insurance factors. Results: The no-shows rate for appointments was significantly higher for the HPV-OPSCC cohort (4.6% vs. 2.2% p < 0.001). The HPV-OPSCC cohort missed 36% of their appointments. Black, Hispanic, younger, those who have ever smoked and patients with advanced tumor stage all had statistically significantly higher no-show rates (p < 0.01). Conclusions: Treatment delay impacts cancer treatment efficacy and no-show appointments burden medical systems. Further research into targeted interventions is needed to lower barriers for attending appointments.

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Use Of Function Diagrams In Physiology Education, Thad E. Wilson, Brian A. Jackson, B. Peter Sawaya Jun 2026

Use Of Function Diagrams In Physiology Education, Thad E. Wilson, Brian A. Jackson, B. Peter Sawaya

Physiology Faculty Publications

Function diagrams focus on physiological concepts rather than associated structures and can serve as elaboration tools and mnemonic aids. A function diagram prototype of the gastrointestinal system was recently described (Wilson TE, Barrett KE. Adv Physiol Educ 45: 264-268, 2021). In this article, a functional diagram of the glomerulus, nephron, urinary system, and bladder is proposed. Colloquially named "Nessie the Nephron" to loosely capture the looping structure and elusive understanding of renal blood flow, glomerular filtration, and epithelial transport for the student, not to mention the nearly mythical countercurrent multiplier. "Navigating the Lochs" references Nessie's possible habitat and more importantly …

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Provider And Patient Perspectives On The Diagnosis And Treatment Of Alzheimer's Disease, Philippe Amouyel, Sandrine Andrieu, Angela Bradshaw, Ralph C. Carmona, Magali Dumont, Lea Tenenholz Grinberg, Takeshi Iwatsubo, Oskar Hansson, Clifford R. Jack, Gregory A. Jicha, Simin Mahinrad, Eric Mcdade, Catherine J. Mummery, Ronald C. Petersen, Shelagh Robinson, Julie A. Schneider, Lenny Shellcross, Amanda G. Smith, Heather M. Snyder, Beth Tapply, Charlotte Teunissen, Wiesje M. Van Der Flier, Bruno Vellas, David Wallon, Jeff D. Williamson, Donna Wilcock, Maria C. Carrillo Jun 2026

Provider And Patient Perspectives On The Diagnosis And Treatment Of Alzheimer's Disease, Philippe Amouyel, Sandrine Andrieu, Angela Bradshaw, Ralph C. Carmona, Magali Dumont, Lea Tenenholz Grinberg, Takeshi Iwatsubo, Oskar Hansson, Clifford R. Jack, Gregory A. Jicha, Simin Mahinrad, Eric Mcdade, Catherine J. Mummery, Ronald C. Petersen, Shelagh Robinson, Julie A. Schneider, Lenny Shellcross, Amanda G. Smith, Heather M. Snyder, Beth Tapply, Charlotte Teunissen, Wiesje M. Van Der Flier, Bruno Vellas, David Wallon, Jeff D. Williamson, Donna Wilcock, Maria C. Carrillo

Neurology Faculty Publications

Since 2016, the Alzheimer's Association and the Fondation Alzheimer have hosted Global Alzheimer's Leadership Series (GoALS) global think tanks, with world-leading experts for innovative discussions to advance Alzheimer's disease (AD) research and care. The second GoALS think tank, held in June 2024 in Paris, focused on the relationship between biological changes and clinical manifestations of AD in the context of the evolving therapeutic landscape. Discussions spanned real-world experiences of providers, patients, and their families, theoretical considerations, and health system challenges. The lived experience perspective was central to these discussions. The importance of shared decision-making, clear and transparent communication, and the …

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Soybean Plant Population Density Recommendations Across The United States, Giovani Preza Fontes, Carrie Ortel, Emma Macham, David Moseley, Shawn Conley, Chad Lee, Mark A. Licht, Laura E. Lindsey, Haleigh J. Ortmeier-Clarke, Rachel Vann, Maninder P. Singh, Seth Naeve, Jeremy Ross, Jake Mcneal, Michael Plumblee, Shaun Casteel, Eros Francisco, Michael J. Mulvaney, Nicolas Cafaro La Menza, Andre Froes De Borja Reis, Daniela Carrijo, Emerson Nafziger Jun 2026

Soybean Plant Population Density Recommendations Across The United States, Giovani Preza Fontes, Carrie Ortel, Emma Macham, David Moseley, Shawn Conley, Chad Lee, Mark A. Licht, Laura E. Lindsey, Haleigh J. Ortmeier-Clarke, Rachel Vann, Maninder P. Singh, Seth Naeve, Jeremy Ross, Jake Mcneal, Michael Plumblee, Shaun Casteel, Eros Francisco, Michael J. Mulvaney, Nicolas Cafaro La Menza, Andre Froes De Borja Reis, Daniela Carrijo, Emerson Nafziger

Plant and Soil Sciences Faculty Publications

Rising production costs and declining commodity prices have compelled farmers to reassess their input and management strategies. Soybean [Glycine max (L.) Merr] seed costs, in particular, have continued to increase due to advances in biotechnology, higher-yielding germplasm, and available seed treatments, accounting for 32–35% of the total operational expenses in current soybean production systems. Optimizing seeding rate is therefore one area of consideration for improving profitability and maximizing return on investment. However, soybean yield response to plant population density is influenced by the combination of several factors, including water availability, temperature, radiation interception, planting practices, and crop growth and development. …

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School Renewal And School Well-Being, Jianping Shen, John Lane, Patricia Reeves, Siche Feng, Xin Ma Jun 2026

School Renewal And School Well-Being, Jianping Shen, John Lane, Patricia Reeves, Siche Feng, Xin Ma

Educational, School, and Counseling Psychology Faculty Publications

In this longitudinal case study, we examined school well-being during the change process. We operationalized the change process as the school renewal model and viewed school well-being from the perspective of the PERMA (positive emotion, engagement, relationships, meaning, and accomplishment) model. We found that all elements of the PERMA model were manifested in the school renewal process and that the school renewal process was not dominated solely by conflict and tension, as the literature typically suggests about the change process. The findings of the study suggest the possibility of reframing tension as productive rather than detrimental in the school renewal …

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Cardioprotective Effects Of 1,3 Butanediol In Masld Via Reversal Of Cardiac Lipid Accumulation And Suppression Of Cardiac Fibrosis, Olufunto O. Badmus, Landon D. Parrow, Karis E. Mcgowen, La Brenda Bell, Jennifer R. Greer, Marcela De Carvalho Cruz, Terry D. Hinds, David E. Stec Jun 2026

Cardioprotective Effects Of 1,3 Butanediol In Masld Via Reversal Of Cardiac Lipid Accumulation And Suppression Of Cardiac Fibrosis, Olufunto O. Badmus, Landon D. Parrow, Karis E. Mcgowen, La Brenda Bell, Jennifer R. Greer, Marcela De Carvalho Cruz, Terry D. Hinds, David E. Stec

Markey Cancer Center Faculty Publications

Metabolic dysfunction-associated steatotic liver disease (MASLD) is highly associated with the development of cardiovascular disease (CVD); however, the mechanisms responsible are currently unknown. We have developed a model of MASLD due to the loss of hepatocyte peroxisome proliferator-activated receptor α (PPARαHEPKO). We found that plasma beta-hydroxybutyrate (BHOB) levels were significantly reduced in PPARαHEPKO mice and aimed to investigate the therapeutic potential of restoring BHOB levels in the development of CVD in these mice. Thirty-week-old PPARαHEPKO and control PPARαFL/FL mice were randomized to receive 1,3 butanediol (1,3-BDO), a precursor of BHOB, in drinking water for 6 …

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Antioxidant Therapy Reverses Hepatotoxicity Induced By Microcystin-Lr In A Cellular Model Of Metabolic Dysfunction-Associated Steatotic Liver Disease (Masld), Apurva Lad, Jason Kindle, Prajwal Hegde, Gabriel G. Kleer, Andrew L. Kleinhenz, Johnna A. Birbeck, Judy Westrick, Nicholas J. Peraino, Terry D. Hinds, Neeraja Purandare, Andrew M. Fribley, Steven T. Haller, David J. Kennedy Jun 2026

Antioxidant Therapy Reverses Hepatotoxicity Induced By Microcystin-Lr In A Cellular Model Of Metabolic Dysfunction-Associated Steatotic Liver Disease (Masld), Apurva Lad, Jason Kindle, Prajwal Hegde, Gabriel G. Kleer, Andrew L. Kleinhenz, Johnna A. Birbeck, Judy Westrick, Nicholas J. Peraino, Terry D. Hinds, Neeraja Purandare, Andrew M. Fribley, Steven T. Haller, David J. Kennedy

Markey Cancer Center Faculty Publications

Microcystin-LR (MC-LR) is a potent hepatotoxin that has been shown to cause liver damage even at doses lower than the established Low Observable Adverse Effect Level (LOAEL) of 200 μg/kg in animal models. We have previously observed that low-dose exposure to MC-LR in animals with diet-induced Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) and subsequent treatment with antioxidants like N-acetylcysteine (NAC) and the Na+/K+ ATPase-Src kinase inhibitor pNaKtide significantly alleviated hepatic infiltration of immune cells, downregulated markers of inflammation and hepatotoxicity, increased the breakdown of the toxin molecule, and restored phase I and II drug metabolism pathways, including …

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Weaning Stress Induced Alterations To The Hypothalamic-Pituitary-Thyroid And -Adrenal Axes In Swine, Isabel B. Walpole, Alyssa A. Smith, Kaylyn G. Rudy, Dayeon Jeon, J. Scott Radcliffe, J. Alex Pasternak Jun 2026

Weaning Stress Induced Alterations To The Hypothalamic-Pituitary-Thyroid And -Adrenal Axes In Swine, Isabel B. Walpole, Alyssa A. Smith, Kaylyn G. Rudy, Dayeon Jeon, J. Scott Radcliffe, J. Alex Pasternak

Animal and Food Sciences Faculty Publications

Combined modulation of the hypothalamic–pituitary–thyroid (HPT) and hypothalamic–pituitary–adrenal (HPA) axes is known to play a critical role in maintaining physiological stability in response to stress. In this study, stress induced modulation of these axes was examined using 20 pigs/treatment either weaned (WN), weaned with feed/water restriction 9 h (FR), transported 9 h (TRANS), or remaining with sow (SOS) and euthanized at 32 or 56 h post-weaning. Serum cortisol, thyroxine (T4), and triiodothyronine (T3) were measured before weaning and after 24, 32, and 56 h with no difference in cortisol concentrations among treatments at any timepoint. However, both T3 and T4 …

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Friendships And Coping Among Adolescents With Lgbtq+ Parents, Jacob S. Withrow, Nita U. Kulkarni, Rachel H. Farr Jun 2026

Friendships And Coping Among Adolescents With Lgbtq+ Parents, Jacob S. Withrow, Nita U. Kulkarni, Rachel H. Farr

Psychology Faculty Publications

Adolescents with LGBTQ+ parents and LGBTQ+ adolescents navigate unique social and identity-related challenges as compared to those without minoritized sexual and/or gender identities. Adolescents with LGBTQ+ parents (regardless of their own sexual or gender identity) and adolescents who personally identify as LGBTQ+ are distinct populations, though they sometimes overlap. Research on adolescents with LGBTQ+ parents has often focused on parent–adolescent relationships and family structures. How do friends help youth cope with identity-based minority stressors, like peer microaggressions, bullying, and exclusion, common for those with minoritized identities? Friendships are developmentally pivotal during adolescence, shaping social competence, identity exploration, and psychological adjustment. …

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Selection For Specific Leaf Weight In Reed Canarygrass And Its Effects On The Plant, I T. Carlson, D K. Christensen, R B. Pearce May 2026

Selection For Specific Leaf Weight In Reed Canarygrass And Its Effects On The Plant, I T. Carlson, D K. Christensen, R B. Pearce

IGC Proceedings (1977-2023)

Specific leaf weight (SL W, dry weight/unit leaf area) may serve as a selection criterion for forage yield through a positive rela• tionship with photosynthesis. Two cycles of phenotypic selection for high and low SLW were conducted in reed canarygrass (Phalaris anmdinacea L.) to investigate direct and correlated responses, particularly those related to yield and quality of forage. In a space-planted test, average direct responses from two cycles of selection for high and low SLW were 23% and 19%, respectively. Significant correlated responses were obtained for ten traits. Compared with the low-SLW cycle-2 population, the high SLW cycle-2 population averaged …

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Valorisation Of Bourbon Distillery Waste Into Single-Source Hybrid Lithium-Ion Capacitors, Josiel Barrios Cossio, Juan Luis Gómez-Urbano, Sandesh Darlami-Magar, Rodney Andrews, Ignacio Martin-Gullon, Andrea Balducci, Marcelo I. Guzman May 2026

Valorisation Of Bourbon Distillery Waste Into Single-Source Hybrid Lithium-Ion Capacitors, Josiel Barrios Cossio, Juan Luis Gómez-Urbano, Sandesh Darlami-Magar, Rodney Andrews, Ignacio Martin-Gullon, Andrea Balducci, Marcelo I. Guzman

Mechanical Engineering Faculty Publications

Bourbon, an iconic American whiskey, is primarily produced in Kentucky, which accounts for 95% of the world's supply. Between 2000 and 2024, bourbon output in Kentucky increased sixfold, creating significant sustainability challenges, particularly the disposal of spent grains (stillage), a high-volume byproduct generated at 6–10 times the volume of bourbon produced. This study presents a scalable strategy to upcycle bourbon stillage into high-performance carbon materials for energy storage applications. The process involves different thermal and chemical treatments to obtain both activated and hard carbons. The resulting activated carbons assembled into symmetric electric double-layer capacitors (EDLCs) deliver outstanding electrochemical performance: 96 …

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A Mixed Methods Examination Of Organizational Approaches To Fentanyl Test Strip Distribution And Training Across Multiple States, Kitty H. Gelberg, Megan E. Hall, Janet E. Childerhose, Mary R. Russo, Fernando Montero, Kaleigh Niles, Jill Oliveri, Haley Ramsey Harden, Rachel A. Vickers-Smith, Arnie Aldridge, Sarah G. Stenger, Katherine R. Marks, Louisa Gilbert, Sharon L. Walsh, Nabila El-Bassel, Carter Roeber, Redonna Chandler May 2026

A Mixed Methods Examination Of Organizational Approaches To Fentanyl Test Strip Distribution And Training Across Multiple States, Kitty H. Gelberg, Megan E. Hall, Janet E. Childerhose, Mary R. Russo, Fernando Montero, Kaleigh Niles, Jill Oliveri, Haley Ramsey Harden, Rachel A. Vickers-Smith, Arnie Aldridge, Sarah G. Stenger, Katherine R. Marks, Louisa Gilbert, Sharon L. Walsh, Nabila El-Bassel, Carter Roeber, Redonna Chandler

Epidemiology and Environmental Health Faculty Publications

Background: Fentanyl test strips (FTS) have become a critical harm reduction tool, allowing people who use drugs (PWUD) to detect fentanyl in their drug supply and make informed decisions about their drug use. While FTS distribution is increasingly common, there is limited understanding of distribution strategies used by community organizations, and the education and training provided around FTS use. Given the proliferation of fentanyl in the drug supply, and the diverse motivations of PWUD, research is needed to better understand FTS distribution and training practices. This study examines FTS distribution strategies, training approaches, and the facilitators and barriers faced by …

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Postapproval Study For Brain-Responsive Neurostimulation For Drug-Resistant Focal Epilepsy, Dawn Eliashiv, Vikram R. Rao, Barbara C. Jobst, Jerzy P. Szaflarski, John D. Rolston, Lesley C. Kaye, Taneeta Mindy Ganguly, Katie Bullinger, Patricia C. Dugan, David E. Burdette, Angela Y. Peters, Atif Sheikh, Kevin F. Haas, Dileep R. Nair, Lilit Mnatsakanyan, Imran H. Quraishi, Meriem K. Bensalem-Owen, Michael J. Doherty, Babak Razavi, Tiffany L. Fisher, Christopher Skidmore, Pradeep N. Modur, Tawnya M. Constantino, Vicenta Salanova, Andrew J. Cole, Olga Taraschenko, Angelica Rivera-Cruz, James W. Wheless, Nitin Tandon, Antoaneta Balabanov, Sami Aboumatar May 2026

Postapproval Study For Brain-Responsive Neurostimulation For Drug-Resistant Focal Epilepsy, Dawn Eliashiv, Vikram R. Rao, Barbara C. Jobst, Jerzy P. Szaflarski, John D. Rolston, Lesley C. Kaye, Taneeta Mindy Ganguly, Katie Bullinger, Patricia C. Dugan, David E. Burdette, Angela Y. Peters, Atif Sheikh, Kevin F. Haas, Dileep R. Nair, Lilit Mnatsakanyan, Imran H. Quraishi, Meriem K. Bensalem-Owen, Michael J. Doherty, Babak Razavi, Tiffany L. Fisher, Christopher Skidmore, Pradeep N. Modur, Tawnya M. Constantino, Vicenta Salanova, Andrew J. Cole, Olga Taraschenko, Angelica Rivera-Cruz, James W. Wheless, Nitin Tandon, Antoaneta Balabanov, Sami Aboumatar

Neurology Faculty Publications

BACKGROUND AND OBJECTIVES: Neuromodulation therapies are approved for the treatment of focal epilepsy based on data from randomized controlled trials (RCTs). After approval of a responsive direct brain stimulation device (The RNS System for focal epilepsy), the Food and Drug Administration required a prospective study to evaluate whether real-world safety and effectiveness differed from outcomes in the RCT. METHODS: This open-labeled study enrolled adult participants who met the RNS System-approved indication for use. The primary effectiveness end point was median percent change in seizure frequency at 3 years of treatment. Interim safety is presented; the primary safety endpoint analysis will …

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Elevated Plasma Cholesterol Improves Sepsis Outcome By Promoting Hepatic Metabolic Reprogramming, Qian Wang, Jianyao Xue, Ling Guo, Dan Hao, Misa Ito, Rianna Reese, Bin Huang, Congqing Wu, Xiang An Li May 2026

Elevated Plasma Cholesterol Improves Sepsis Outcome By Promoting Hepatic Metabolic Reprogramming, Qian Wang, Jianyao Xue, Ling Guo, Dan Hao, Misa Ito, Rianna Reese, Bin Huang, Congqing Wu, Xiang An Li

Markey Cancer Center Faculty Publications

Background – Sepsis is a life-threatening condition with high mortality and limited therapeutic options. This study investigated the association between plasma cholesterol levels and sepsis survival and explored the mechanisms by which elevated cholesterol confers protection. Methods – We analyzed 2, 787 sepsis patients from the MIMIC-IV database, comparing cholesterol levels between 28-day survivors and non-survivors and assessing mortality risk using multivariable Cox regression. To test causality, C57BL/6J mice were fed either a high-cholesterol diet (HCD) or a regular diet (RD) before cecal ligation and puncture (CLP). Results – Survivors had significantly higher cholesterol than non-survivors (median 135 vs. 126 …

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From Demolition To Digital: Using Virtual Reality To Interpret Hamilton House, Hannah R. Miller May 2026

From Demolition To Digital: Using Virtual Reality To Interpret Hamilton House, Hannah R. Miller

Graduate Final Projects

This master’s project investigates the potential of digital reconstruction as a tool for documenting and interpreting demolished historic resources, using Hamilton House as a case study. Employing a mixed-methods approach, the research integrates archival analysis with digital modeling to recreate the spatial context of the house. By grounding the digital model in historical evidence, this study examines how virtual reconstruction can be used to interpret social relationships, patterns of use, and lived experiences that are not fully captured through traditional means of documentation. This project also considers the interpretive implications of reconstructing using fragmentary historical data, addressing the possibilities and …

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From Ash Pond To Concrete: A Two-Step Treatment For Enhancing Reactivity Of Reclaimed Ashes, Aysan Farajnia May 2026

From Ash Pond To Concrete: A Two-Step Treatment For Enhancing Reactivity Of Reclaimed Ashes, Aysan Farajnia

World of Coal Ash Proceedings

The closure of coal-fired power plants has led to a shortage of fly ash for concrete, increasing interest in alternative Supplementary Cementitious Materials (SCMs). Reclaimed or harvested fly ash represents a promising SCM, but often fails to meet ASTM specifications due to impurities, variable composition, and low reactivity. This study highlights a two-phase evaluation of harvested coal ash from a local ash pond in Illinois. The first phase characterized ashes from different depths and locations based on chemical composition and pozzolanic reactivity. The second phase focused on a novel two-step treatment consisting of magnetic separation and mechanical grinding. On average, …

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Narrative Power: Strengthening Coal Ash Communications In A Shifting Policy And Media Environment, Tamara Hinton May 2026

Narrative Power: Strengthening Coal Ash Communications In A Shifting Policy And Media Environment, Tamara Hinton

World of Coal Ash Proceedings

As coal ash management and beneficial use practices continue to advance and regulatory frameworks evolve, the industry still faces a persistent challenge: sharing its story clearly, credibly, and proactively to audiences beyond engineers and regulators. Public perception, media narratives, and stakeholder understanding increasingly influence policy decisions, project timelines, and market opportunities. This session focuses on how strategic communications can serve as a critical tool to support responsible coal ash management and beneficial use. This presentation explores how utilities and industry partners can move from reactive communications to a more deliberate, strategic approach that strengthens trust, mitigates risk, and reinforces the …

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Liquefaction Susceptibility And Brittleness Of Coal Ash - A State Parameter Approach, Suafa'i Manson, Benoit Wentzinger, Scott Lines May 2026

Liquefaction Susceptibility And Brittleness Of Coal Ash - A State Parameter Approach, Suafa'i Manson, Benoit Wentzinger, Scott Lines

World of Coal Ash Proceedings

Limited data exists on the liquefaction susceptibility of combined fly ash and bottom ash deposits. Their low plasticity and settling density pose a risk of liquefaction under certain triggers. The liquefaction potential is linked to the in-situ state, defining its shearing behaviour as dilative or contractive based on relative density and effective confining stress. This can be assessed using the state parameter (Ψ) concept from critical state soil mechanics theory. This paper presents findings from a follow-up to our 2021 study, which used cone penetration test (CPT) based methods to estimate the in-situ state parameter and perform liquefaction susceptibility screening. …

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Mass Spectrometry-Based Spatial Imaging Of The Cochlea, Roberto A. Ribas, Qun Tang, Scarlett I. Caffee, Cameron J. Shedlock, Tara R. Hawkinson, Abigail K. Dragich, Borhane E.C. Ziani, Franca Bucco Paolasso, Alyson P. Black, Xin Ma, Harshitha C. Kota, Li Chen, Gregory I. Frolenkov, Derek B. Allison, Matthew S. Gentry, Ramon C. Sun, Craig W. Vander Kooi May 2026

Mass Spectrometry-Based Spatial Imaging Of The Cochlea, Roberto A. Ribas, Qun Tang, Scarlett I. Caffee, Cameron J. Shedlock, Tara R. Hawkinson, Abigail K. Dragich, Borhane E.C. Ziani, Franca Bucco Paolasso, Alyson P. Black, Xin Ma, Harshitha C. Kota, Li Chen, Gregory I. Frolenkov, Derek B. Allison, Matthew S. Gentry, Ramon C. Sun, Craig W. Vander Kooi

Physiology Faculty Publications

Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry Imaging (MALDI-MSI) is transforming spatial molecular studies. However, applying MALDI-MSI to small, anatomically complex tissues remains challenging. One such structure is the cochlea, the auditory part of the inner ear that is critical for hearing. To address these challenges, we developed and implemented a streamlined workflow for sample preparation and processing to obtain MALDI-MSI data on mouse cochlea. Sample acquisition was optimized to minimize time and processing steps, allowing use of flash-frozen neonatal mouse heads. This workflow enabled high spatial resolution metabolomic and lipidomic imaging of the sagittally cryosectioned mouse cochlea using N-(1-naphthyl) ethylenediamine dihydrochloride …

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Coal Ash-Derived Aluminosilicate Precursors: A Chemical Engineering Approach To Geopolymer Characterization, Hafiz Abdul Basit, Abdullah Bashir, Abdur Raafey May 2026

Coal Ash-Derived Aluminosilicate Precursors: A Chemical Engineering Approach To Geopolymer Characterization, Hafiz Abdul Basit, Abdullah Bashir, Abdur Raafey

World of Coal Ash Proceedings

The chemical and microstructural evaluation of coal-derived aluminosilicate precursors is critical for understanding their suitability in advanced construction material systems. In this study, a characterization of Class F fly ash, ground granulated blast furnace slag (GGBFS), and Silica Fumes (SF) was conducted to elucidate their morphological and elemental features. Scanning Electron Microscopy (SEM) was used to assess particle morphology and surface characteristics (porosity, particle diameter, particle geometry), and Energy-Dispersive X-ray Spectroscopy (EDS) to determine elemental composition and distribution. The analysis revealed distinct morphological and compositional differences among the precursors, including spherical fly ash particles, calcium-rich slag phases, and ultra-fine silica …

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Plasma Coal Ash Processing For Enhanced Recovery Of Rare Earth Elements & Precious Metals: Proven From R&D To Commercial Plants, George Paskalov, Victoria Campbell, Jason Honigberg May 2026

Plasma Coal Ash Processing For Enhanced Recovery Of Rare Earth Elements & Precious Metals: Proven From R&D To Commercial Plants, George Paskalov, Victoria Campbell, Jason Honigberg

World of Coal Ash Proceedings

Our Radio-frequency Plasma System is an ash pretreatment before the application of extractive metallurgy and addresses current elemental, methodological, and technological limitations of complex and refractory coal ash. Our system data shows from 10-20% improved recovery, to 9x-100x. RFP can access all metals contained in coal ash. Our focus is not on the alteration of established methodologies, such as cyanidation for non-refractory ore, which has a proven return and capacity to achieve target revenue at-scale. Using the RFP systems, no waste is created, overburden can be more easily dealt with, and no metal content will be left behind. We assert …

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Comparison Of Residuals From Neighboring Power Stations With Different Coal Combustion Technologies, Allan Kolker, Denise Levitan, Brett Valentine May 2026

Comparison Of Residuals From Neighboring Power Stations With Different Coal Combustion Technologies, Allan Kolker, Denise Levitan, Brett Valentine

World of Coal Ash Proceedings

Due to the ongoing need for critical minerals, coal combustion residuals (CCR), like fly ash, have been evaluated as a potential source of critical minerals, particularly rare earth elements (REEs). Previous studies have found that REEs in fly ash are largely contained within aluminosilicate glass from which they are difficult to extract. However, these studies have predominantly studied CCR from conventional pulverized coal fired (PCF) plants. PCF plants use higher temperatures (≥1300°C) than do circulating fluidized-bed (CFB) plants (~900-950°C). Samples of feed coal, fly ash, and bottom ash were collected from two adjacent Vietnamese coal-fired power stations, one with a …

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Abundances Of Elements In Global Coals, Shifeng Dai May 2026

Abundances Of Elements In Global Coals, Shifeng Dai

World of Coal Ash Proceedings

The abundance of elements in coal is important not only because it provides a solid scientific and practical foundation for various geochemical comparisons, but also because it helps address broader questions in Earth Sciences. In this study, data on major and trace elements in global coals comprising hundreds of thousands of coal samples were compiled from peer-reviewed journal articles, books, various databases, dissertations, and technical reports. These data formed the basis for estimating element abundances in global coals presented in this study. All collected data were rigorously screened for reliability, and any records with questionable quality were excluded from the …

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Distinguishing Ccp From Nuclear Impacts In Groundwater, Lea Millet May 2026

Distinguishing Ccp From Nuclear Impacts In Groundwater, Lea Millet

World of Coal Ash Proceedings

As the energy transition from fossil fuels to other generation technologies continues, many companies worldwide are evaluating the feasibility of constructing nuclear power plants at sites previously used for coal-powered generation. Thermal power plant sites offer advantages for siting nuclear generation such as proximity to cooling water and grid connections; however existing impacts to groundwater from coal combustion product (CCP) management units may confound monitoring programs designed to detect impacts from nuclear operations. For example, boron and lithium may be present in waters associated with CCP management and nuclear power plant operations, and potassium that often has concentrations above background …

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The Age-Dependent Resident Myonuclear Multi-Omic Response To An Acute Skeletal Muscle Hypertrophic Stimulus In Mice, Pieter J. Koopmans, Ronald G. Jones, Ana Regina Cabrera, Francielly Morena, Nicholas P. Greene, John J. Mccarthy, Ahmed Ismaeel, Yuan Wen, Kevin A. Murach May 2026

The Age-Dependent Resident Myonuclear Multi-Omic Response To An Acute Skeletal Muscle Hypertrophic Stimulus In Mice, Pieter J. Koopmans, Ronald G. Jones, Ana Regina Cabrera, Francielly Morena, Nicholas P. Greene, John J. Mccarthy, Ahmed Ismaeel, Yuan Wen, Kevin A. Murach

Physiology Faculty Publications

A detailed analysis of how muscle fiber nuclei (myonuclei) respond to a hypertrophic stimulus could provide a critical step toward understanding compromised skeletal muscle plasticity with age. We used recombination-independent doxycycline-inducible myonucleus-specific fluorescent labelling, tissue RNA-sequencing, myonuclear DNA methylation analysis, multi-omic integration, and single myonucleus RNA-sequencing (smnRNA-seq) to define the molecular characteristics of adult (6–8 month) and aged (24 month) murine skeletal muscle after acute mechanical overload (MOV). In adult and aged MOV muscles, we found that: 1) similarities in the transcriptional response to loading—specifically in metabolism genes – were partly explained by a post-transcriptional microRNA-mediated mechanism that we corroborated …

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Mosdef-3d, Natalie Lam, Alice E. Shapley, Ryan L. Sanders, Tuan Do, Tucker Jones, Alison Coil, Mariska Kriek, Bahram Mobasher, Naveen A. Reddy, Brian Siana, Leonardo Clarke May 2026

Mosdef-3d, Natalie Lam, Alice E. Shapley, Ryan L. Sanders, Tuan Do, Tucker Jones, Alison Coil, Mariska Kriek, Bahram Mobasher, Naveen A. Reddy, Brian Siana, Leonardo Clarke

Physics and Astronomy Faculty Publications

We present spatially resolved rest-frame optical emission line maps of four galaxies at z ∼ 2 observed with the Keck/OH-Suppressing Infra-Red Imaging Spectrograph to study the physical conditions of the interstellar medium (ISM) at cosmic noon. Our analysis of strong emission line ratios in these galaxies reveals an offset from the local star-forming locus on the Baldwin–Phillips–Terlevich diagram but agrees with other star-forming galaxies at similar redshifts. Despite the offset toward higher [O iii] λ5008/Hβ and [N ii] λ6585/Hα, these strong line ratios remain consistent with or below the maximum starburst threshold even in the inner ∼1 kpc region of …

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Building Resilience When Disaster Strikes, Anna G. Kalema, Felipe González-Seguel, Louisa A. Summers, Esther E. Dupont-Versteegden, Ashley A. Montgomery-Yates, Kirby P. Mayer May 2026

Building Resilience When Disaster Strikes, Anna G. Kalema, Felipe González-Seguel, Louisa A. Summers, Esther E. Dupont-Versteegden, Ashley A. Montgomery-Yates, Kirby P. Mayer

Physiology Faculty Publications

No abstract provided.

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Election Fraud In The American Mind, Mitchell Brown, Spencer Goidel, Soren Jordan, Bridgett A. King, Isaac Westfall, Ryan Williamson May 2026

Election Fraud In The American Mind, Mitchell Brown, Spencer Goidel, Soren Jordan, Bridgett A. King, Isaac Westfall, Ryan Williamson

Political Science Faculty Publications

Objective: Disputes over election fraud have become a defining feature of contemporary American politics, yet it remains unclear whether partisans are disagreeing about the same underlying phenomenon. This article examines how Americans understand and interpret the phrase “election fraud” and whether partisan divisions reflect differences in concern about fraud or differences in what the term itself is taken to mean. Methods: We use novel survey questions included in our team's module of the 2024 Cooperative Election Study (N = 1000). An open-ended question captures respondents’ own top-of-mind associations with the phrase “election fraud,” while a closed-ended item asks respondents to …

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A Two-Stage Screening Approach Integrated With Gwas For Rare Phenotypes Such As Spontaneous Haploid Genome Doubling In Maize, Mercy Fakude, Tyler L. Foster, Yu Ru Chen, Ann Murithi, Siddique Imran Aboobucker, Ursula Karoline Frei, Philip M. Dixon, Thomas Lübberstedt May 2026

A Two-Stage Screening Approach Integrated With Gwas For Rare Phenotypes Such As Spontaneous Haploid Genome Doubling In Maize, Mercy Fakude, Tyler L. Foster, Yu Ru Chen, Ann Murithi, Siddique Imran Aboobucker, Ursula Karoline Frei, Philip M. Dixon, Thomas Lübberstedt

Plant and Soil Sciences Faculty Publications

Spontaneous haploid genome doubling (SHGD) is a valuable trait in maize breeding, enabling the development of doubled haploid (DH) lines without chemical chromosome doubling. However, SHGD is a rare phenotype, expressed in only a small fraction of maize germplasm, making its identification resource-intensive. This study evaluated the efficiency of a two-stage field screening approach designed to identify maize genotypes with high haploid male fertility (HMF), a key indicator of SHGD potential. Simulation analyses showed that evaluating 50 haploid plants per genotype, combined with a 25% HMF threshold, provides an optimal balance between detection accuracy and resource efficiency. Across three growing …

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Case Report: Gangrene After One Dose Of Investigational Stannic Pentetate Radiopharmaceutical, Zin W. Myint, Riham H. El Khouli, Bryan P. Lemieux, Charles A. Kunos May 2026

Case Report: Gangrene After One Dose Of Investigational Stannic Pentetate Radiopharmaceutical, Zin W. Myint, Riham H. El Khouli, Bryan P. Lemieux, Charles A. Kunos

Radiology Faculty Publications

Introduction – Bone-seeking radiopharmaceuticals are the treatment of choice with clinical benefits for patients with extensive skeletal metastases, but they can also cause serious radiation-related adverse events (rrAEs). Management of rare and severe radiopharmaceutical rrAEs remains challenging because of incomplete knowledge of their natural history and pathogenetic mechanisms. We report a case of unlikely related gangrene following a protracted hospitalization after one dose of investigational [117mSn]tin-117m-diethylenetriaminepentaacetic acid (Sn-117m-DTPA) for treatment of extensive skeletal metastases from castration-resistant prostate cancer (mCRPC). Case presentation – An 80-year-old man with innumerable painful skeletal metastases from mCRPC developed anorexia and bilateral ankle edema with serous-draining …

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