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Party Over Country: The Inability For Congress To Check The Executive, Jordin A. Dickerson

Kentucky Law Journal

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Federal Prosecution In The Shadows Of Constitutional Immunity, J. Richard Broughton

Kentucky Law Journal

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President Biden's Influence On The Use Of Executive Privilege, Mitchel A. Sollenberger, Mark J. Rozell

Kentucky Law Journal

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Executive Immunity, Corruption, And The Rule Of Law: Death By A Thousand Cuts, Kimberly Breedon

Kentucky Law Journal

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The Removal Responsibility, Kevin Frazier

Kentucky Law Journal

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Table Of Contents For Volume 113, Issue 4, Kentucky Law Journal

Kentucky Law Journal

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Somebody's Watching Me: Modern Abusers Use Modern Methods Of Control, Savannah Molyneaux

Kentucky Law Journal

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Happy Belated Iep: How A Notice Of Procedural Safeguards Fails Children With Specific Learning Disabilities, Chrystal Clodomir

Kentucky Law Journal

No abstract provided.

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Decolonizing The Law Of The U.S. Virgin Islands, Anthony M. Ciolli

Kentucky Law Journal

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Building Jerusalem: Commercial Law And Ethics Of The Benefit Corporation, Jeff Lingwall, Susan Park

Kentucky Law Journal

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Campus Coverage: How Biden's Title Ix Regulations Threaten Free Speech, Academic Freedom, And University Liability, Alex Drury

Kentucky Law Journal

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The Fall Of America's Final Free Labor Market: Considering The New Age College Athlete As An Employee Under The Nlra And Flsa, Ethan Schaaf

Kentucky Law Journal

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Reaching For Starz: The Negative Impact Of Creating Limitations On Damages In Timely Copyright Claims, Lindley Williams

Kentucky Law Journal

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Against Activist Cooperation Agreements, Jennifer O'Hare

Kentucky Law Journal

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Joint Optical And Infrared Observations Of Nitrogen And Oxygen Reveal The Dust-Obscured Gas In Haro 3, Yuguang Chen, Tucker Jones, Ryan L. Sanders, Dario Fadda, Jessica Sutter, Robert Minchin, Nikolaus Z. Prusinski, Sunny Rhoades, G. C. Keerthi Vasan, Charles C. Steidel, Erin Huntzinger, Paige Kelly, Danielle A. Berg, Fabio Bresolin, Rodrigo Herrera-Camus, Ryan J. Rickards Vaught, Guido Roberts-Borsani, Peter Senchyna, Justin S. Spilker, Daniel P. Stark, Benjamin Weiner, D. Christopher Martin, Mateusz Matuszewski, Rosalie C. Mcgurk, James D. Neill

Physics and Astronomy Faculty Publications

Accurate chemical compositions of star-forming regions provide a critical diagnostic tool for characterizing the star formation history and gas flows that regulate galaxy formation. However, the abundance discrepancy factor (ADF) between measurements derived from the “direct” optical electron temperature (T_e) method and those from recombination lines (RLs) introduces a ∼0.2 dex systematic uncertainty in the oxygen abundance. The degree of uncertainty for other elements is unknown. We conduct a comprehensive analysis of O⁺⁺ and N⁺ ion abundances using optical and far-infrared (far-IR) spectra of a star-forming region within the nearby dwarf galaxy Haro 3, which exhibits …

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Taylor Dispersion In Variable-Density, Variable-Viscosity Pulsatile Flows, Prabakaran Rajamanickam, Adam D. Weiss

Progress in Scale Modeling, an International Journal

The phenomenon of Taylor or shear-induced dispersion of a non-passive scalar field in a pulsatile pipe flow is investigated, accounting for the scalar field's influence on fluid density and transport coefficients. By employing multiple scale analysis, an effective one-dimensional, unsteady mixing problem for the scalar field is obtained, which includes the diffusion coefficient for shear-induced dispersion. The resulting governing equations are applicable to a range of scalar transport problems in pulsatile pipe flows.

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Sacbe 1 And Classic Maya Urban Culture, Traci Ardren, Scott R. Hutson, Travis W. Stanton, Patrick Rohrer, Justin P. Lowry

Anthropology Faculty Publications

One of the most significant engineering accomplishments of Maya civilization is Sacbe 1, a raised road connecting the ancient urban centers of Yaxuna and Coba. Using new lidar data in concert with excavation, epigraphic inscriptions, and landscape reconnaissance, we show that settlement and an urban experience emanated westward from Coba along the sacbe. The leaders of Coba - in particular, an ambitious seventh-century queen - used the sacbe to expand the political and cultural influence of their dynasty into the center of the peninsula while securing territory and resources. Gaps in the sacbe, precise delineation of its many curves, and …

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Main And Interactive Effects Of Self-Disgust And Affect Intensity In Predicting The Severity Of Mental Contamination, Contact Contamination, And Ptsd Symptoms, Jordyn M. Tipsword, Grace M. Seymour, Christal L. Badour

Psychology Faculty Publications

Purpose: Self-disgust has been linked to contact contamination (i.e., experiences of dirtiness caused by exposure to a contaminant), mental contamination (i.e., experiences of dirtiness that occur absent a contaminant), and PTSD symptoms in theoretical work. Separate lines of research have also linked higher affect intensity (i.e., the tendency to experience emotions strongly) to negative mental health outcomes, including more severe PTSD symptoms. However, empirical research examining associations between self-disgust and both contamination concerns and PTSD symptoms remains limited, and these associations may differ as a function of affect intensity. Method: The current study evaluated main and interactive effects of self-disgust …

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Intermittent Hypoxemia And Brain Injury Biomarker S100b In Preterm Infants, Elie G. Abu Jawdeh, Linda J. Van Eldik, Jennifer Stevenson, Abhijit Patwardhan, Philip M. Westgate, Lina Chalak, Richard J. Martin, Henrietta S. Bada

Epidemiology and Environmental Health Faculty Publications

Abstract – Introduction: Intermittent hypoxemia (IH) is common in preterm infants and linked to brain injury. S100B is a glial-derived protein that rises early after neural injury and can be measured noninvasively in urine. We evaluated the relationship between IH burden and urinary S100B in preterm infants of ≤32 weeks’ gestation. Methods: Preterm infants of ≤32 weeks’ gestation were prospectively enrolled. Oxygen saturation was continuously monitored, and IH profiles were quantified using validated algorithms. Urine S100B was measured by ultrasensitive immunoassay and normalized for urinary creatinine. Infants with severe intraventricular hemorrhage were excluded. Weighted Spearman correlations examined associations between IH …

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Nitrogenated Graphene Quantum Dot-Derived Copper Single-Atom Catalyst For Oxygen Reduction Reaction, Dawatage Shashika Madushani Perera, Prakhar Sharma, Ayanthi Thisera, Nadeesha Kothalawala, Matthew G. Boebinger, Beth S. Guiton, Doo Young Kim

Chemistry Faculty Publications

Despite the promise of fuel cells as sustainable energy conversion technologies, their widespread adoption is hindered by the high cost of platinum group metal (PGM) catalysts, particularly for catalyzing the oxygen reduction reaction (ORR) at the cathode. Here, we report copper-based single-atom catalysts (Cu-SACs) as cost-effective non-PGM alternatives for ORR. The catalysts were synthesized via simple pyrolysis of pyrene-derived amine-terminated graphene quantum dots (GQDs) in the presence of nitrogen and metal precursors. The abundant nitrogen functionality in GQDs effectively stabilized isolated Cu atoms during their conversion to porous carbon. A subsequent acid-washing step yielded a high density of atomically dispersed …

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Interface-Directed Synthesis Of Cspbbr3-Based Particles With Water-Ode Antisolvent Systems, Saurabh Singh, Xiyu Wen, Fuqian Yang

Chemical and Materials Engineering Faculty Publications

All-inorganic lead halide perovskites, specifically CsPbX₃ (X = I, Cl, Br), have attracted significant attention over the past few years due to their immense potential in optoelectronic devices, such as liquid crystal displays (LCDs), light emitting diodes, photodetectors, and solar cells. Currently, most available synthesis techniques rely on high temperatures, inert environments, and toxic non-polar solvents, with limiting scalability and environmental compatibility. Herein, we present a facile, room-temperature, and partially green approach for synthesizing CsPbBr₃-based particles via a biphasic solvent system comprising non-polar octadecene (ODE) layered over deionized water. By simply tuning the volume ratio of DI …

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Influence Of Film Formation Kinetics On The Dispersion Of Colloidal Quantum Dots In Organic Small Molecule Matrices, Rachel C. Kilbride, Michael P. Weir, James Xiao, Simon A. Dowland, Jurjen F. Winkel, John E. Anthony, Akshay Rao, Richard A.L. Jones, Anthony J. Ryan, Daniel T.W. Toolan

Chemistry Faculty Publications

Improving the dispersion of colloidal quantum dots (QDs) within organic semiconductor (OSC) matrices remains critical for advancing hybrid nanocomposite optoelectronic technologies. This study investigates how film-deposition kinetics influence the morphology of TIPS-tetracene (TIPS-Tc):PbS QD blends, comparing spin-coating and blade coating for QDs ligated with either native oleic acid (OA) or a matched carboxylic acid functionalised tetracene analogue (TET-CA). Films spun-cast at low spin speeds form highly crystalline TIPS-Tc domains with highly aggregated QDs. Increased spin speed induces a deeper solvent quench, driving rapid TIPS-Tc nucleation while kinetically arresting QD diffusion, which improves QD dispersion within the crystalline matrix. TIPS-Tc:PbS-OA blends …

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Stress-Induced Bandgap Modulation In Semiconductor Quantum Wells, Saurabh Singh, Fuqian Yang

Chemical and Materials Engineering Faculty Publications

Strained semiconductor quantum wells have been an active area of research for more than three decades. However, a major part of the reported literature has shown a core focus on the theoretical and experimental investigations of their energy band structures under different internal and external perturbations, taking strain parameters as the basis and studying their resulting effects on various optoelectrical properties of the strained quantum wells. However, since stress parameters can be measured more easily and with an enhanced level of accuracy compared to strain parameters, developing a stress-based analytical framework offers distinct advantages. This study focuses on the theoretical …

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Renin-Angiotensin-Aldosterone System In Preeclampsia: Pathophysiological Insights And Links To Vascular Dementia, Robin C. Finch, Jenny Lutshumba, Elizabeth Mirsky, Esther Ndashaala, Kelsey Bullens, Emma Smith

Pediatrics Faculty Publications

Pre-eclampsia, a condition characterized by new-onset hypertension during pregnancy and one or more indices of organ damage, is a major driver of both short and long-term maternal health outcomes. Individuals with a history of pre-eclampsia are at increased risk for cardiovascular, renal, and other chronic diseases. Recent studies have linked pre-eclampsia history with increased risk of dementia later in life, underscoring the importance of new guidelines emphasizing blood pressure control to reduce the risk of cognitive decline. Unfortunately, neither mechanisms underlying causes of pre-eclampsia nor their links with cognitive function are well understood. Vascular contributions to cognitive impairment and dementia …

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Phase 1 Open-Label Study Of Asp9801, An Oncolytic Virus, In Patients With Advanced Or Metastatic Solid Tumors, John L. Villano, Jason J. Luke, Ricklie Julian, Christos Fountzilas, Manish R. Patel, Michael J. Chisamore, Pranob Bhattacharya, Shigeru Takeshita, Serguei Soukharev, Shunsuke Yamada, Leshi Zhang, Kristopher P. Wentzel

Neurology Faculty Publications

Purpose ASP9801, an oncolytic virus encoding interleukin-7 and interleukin-12, was assessed for safety, tolerability, pharmacokinetics, and antitumor activity in patients with advanced solid tumors in a Phase 1 study. Methods The study comprised Part 1 ASP9801 monotherapy dose escalation and Part 2 dose expansion with ASP9801 monotherapy or plus pembrolizumab. Each part was divided into Groups A (ASP9801 injection into cutaneous/subcutaneous lesions) and B (ASP9801 injection into visceral lesions). Primary objectives were safety and maximum tolerated dose and/or recommended Phase 2 dose expansion (RP2D); secondary objectives included antitumor activity and pharmacokinetics. Results In dose escalation, 17 and 10 patients in …

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Osimertinib Activates A Tgf-Β2-Dependent Secretory Program That Drives Lung Adenocarcinoma Progression, Madhurima Ghosh, Chao Wu, Abhishek Kumar, Monique Nilsson, John V. Heymach, Weina Zhao, Jiang Yu, Xin Liu, Na Ding, Shike Wang, Guan Yu Xiao, Angelo Chen, Kate Grimley, William K. Russell, Chad J. Creighton, Xiaochao Tan, Jonathan M. Kurie

Markey Cancer Center Faculty Publications

EGFR-mutant lung adenocarcinomas (LUADs) that are vulnerable to the EGFR antagonist osimertinib (Osi) eventually relapse, owing in part to the emergence of drug-tolerant persister (DTP) cells that arise through epigenetic mechanisms. Intratumoral DTP cells can herald a worse clinical outcome, but the way in which DTP cells influence LUAD progression remains unclear. Osi-resistant (OR) cells exhibit typical DTP cell features, including a propensity to undergo senescence and epithelial-mesenchymal transition (EMT), which can activate heightened secretory states. Therefore, we postulated that OR cells influence LUAD progression through paracrine mechanisms. To test this hypothesis, we utilized congenic pairs of EGFR-mutant LUAD cell …

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Holographic Duality From Howe Duality, Anatoly Dymarsky, Johan Henriksson, Brian Mcpeak

Physics and Astronomy Faculty Publications

We discuss the holographic correspondence between 3d “Chern-Simons gravity” and an ensemble of 2d Narain code CFTs. Starting from 3d abelian Chern-Simons theory, we construct an ensemble of boundary CFTs defined by gauging all possible maximal subgroups of the bulk one-form symmetry. Each maximal non-anomalous subgroup is isomorphic to a classical even self-dual error-correcting code over ℤ_p × ℤ_p, providing a way to define a boundary “code CFT.” The average over the ensemble of such theories is holographically dual to Chern-Simons gravity, a bulk theory summed over 3d topologies sharing the same boundary. In the case of …

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Human Atrial Skinned Muscle Fibers Exhibit Reduced Length-Dependent Activation But Show Faster Force Development Kinetics Than Ventricular Muscle, Alexandre Lewalle, Gregory Milburn, Jania Bell, Kenneth S. Campbell, Steven A. Niederer

Physiology Faculty Publications

In humans, the left atria (LA) and the left ventricle (LV) play distinct physiological roles and express sarcomeric proteins with chamber-specific patterns. Despite these important differences, most multi-chamber descriptions of the heart assume uniform myocardial properties. To facilitate a more accurate representation of cardiac function, we measured and compared the contractile properties of isolated skinned human LA and LV muscle fibers at 37 °C. Our experimental measurements included the length-dependent activation (LDA) of force in the isometric steady state, the force response to small quick length changes, and tension redevelopment dynamics. The LV measurements display more pronounced LDA behavior compared …

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From Leaky Pipelines To Watering Cans, Samantha Fladd, Sarah Kurnick, Laura E. Heath-Stout, Nala K. Williams, Sarah Simeonoff, Sasha Buckser, Katelyn J. Bishop, Scott R. Hutson, Jessica Maclellan, Marie Matsuda, Sarah E. Oas, Jocelyne M. Ponce, Bruno Athie Teruel, Jaycee Castro, Breeanna Charolla, Adriana M. De León, Luisa Escobar Galo, Lydia D. Evans, Isabella N. Garcia, Kelsey Hoppes, Elena Lompe

Anthropology Faculty Publications

Despite improvement over the past few decades, particularly for white, cisgender women, intersectional gender-based inequality remains prominent within anthropological archaeology and beyond. Building on critiques of the leaky pipeline metaphor laid out in the introduction to this themed issue, and drawing on Black, Indigenous, and Posthumanist Feminisms, we advocate for a metaphorical shift focused on care, inclusivity, and diversity—that of a garden. The garden metaphor provides a way to express and explore the complex and intertwined ways disciplinary norms, institutions, and individuals structure and shape experiences in archaeology. After reviewing the garden metaphor and summarizing previous suggestions for improving equity …

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Hyaluronan 35 Prevents Endotoxin-Mediated Dysregulated Skeletal Muscle Proteostasis During Ethanol Exposure, Nicole Welch, Pugazhendhi Kannan, Gangarao Davuluri, Annette Bellar, Amy H. Attaway, Saurabh Mishra, Jasmin A. Cunningham, Avinash Kumar, Ryan Musich, Elif G. Ertugral, Vandana Agrawal, Isaac L. Hsu, Terri J. Harford, Noah L. Weisleder, Vidula T. Vachharajani, Chandrasekhar R. Kothapalli, Carol A. De La Motte, Laura E. Nagy, Srinivasan Dasarathy

Neurology Faculty Publications

Sarcopenia in alcohol-related liver disease (ALD) is of high clinical significance, but there are no effective treatments. Hyaluronan 35 kDa (HA35), a glycosaminoglycan polymer, modulates responses to Toll-like receptor 4 (TLR4), a lipopolysaccharide receptor, to improve hepatic and macrophage function in ALD. We evaluated skeletal muscle responses to HA35 in preclinical models of ALD. Responses to ethanol, lipopolysaccharide (LPS), and HA35 were studied in differentiated murine C2C12/human-induced pluripotent stem cell (hiPSC)-derived myotubes, and wild-type/HA receptor CD44 knockout (CD44^—/—) mouse models of ALD (mALD). Signaling molecules and measures of protein homeostasis (proteostasis) were quantified by immunoblots, mitochondrial oxidative function …

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Full-Text Articles in Entire DC Network

Party Over Country: The Inability For Congress To Check The Executive, Jordin A. Dickerson

Kentucky Law Journal

Federal Prosecution In The Shadows Of Constitutional Immunity, J. Richard Broughton

Kentucky Law Journal

President Biden's Influence On The Use Of Executive Privilege, Mitchel A. Sollenberger, Mark J. Rozell

Kentucky Law Journal

Executive Immunity, Corruption, And The Rule Of Law: Death By A Thousand Cuts, Kimberly Breedon

Kentucky Law Journal

The Removal Responsibility, Kevin Frazier

Kentucky Law Journal

Table Of Contents For Volume 113, Issue 4, Kentucky Law Journal

Kentucky Law Journal

Somebody's Watching Me: Modern Abusers Use Modern Methods Of Control, Savannah Molyneaux

Kentucky Law Journal

Happy Belated Iep: How A Notice Of Procedural Safeguards Fails Children With Specific Learning Disabilities, Chrystal Clodomir

Kentucky Law Journal

Decolonizing The Law Of The U.S. Virgin Islands, Anthony M. Ciolli

Kentucky Law Journal

Building Jerusalem: Commercial Law And Ethics Of The Benefit Corporation, Jeff Lingwall, Susan Park

Kentucky Law Journal

Campus Coverage: How Biden's Title Ix Regulations Threaten Free Speech, Academic Freedom, And University Liability, Alex Drury

Kentucky Law Journal

The Fall Of America's Final Free Labor Market: Considering The New Age College Athlete As An Employee Under The Nlra And Flsa, Ethan Schaaf

Kentucky Law Journal

Reaching For Starz: The Negative Impact Of Creating Limitations On Damages In Timely Copyright Claims, Lindley Williams

Kentucky Law Journal

Against Activist Cooperation Agreements, Jennifer O'Hare

Kentucky Law Journal

Physics and Astronomy Faculty Publications

Taylor Dispersion In Variable-Density, Variable-Viscosity Pulsatile Flows, Prabakaran Rajamanickam, Adam D. Weiss

Progress in Scale Modeling, an International Journal

Sacbe 1 And Classic Maya Urban Culture, Traci Ardren, Scott R. Hutson, Travis W. Stanton, Patrick Rohrer, Justin P. Lowry

Anthropology Faculty Publications

Main And Interactive Effects Of Self-Disgust And Affect Intensity In Predicting The Severity Of Mental Contamination, Contact Contamination, And Ptsd Symptoms, Jordyn M. Tipsword, Grace M. Seymour, Christal L. Badour

Psychology Faculty Publications

Intermittent Hypoxemia And Brain Injury Biomarker S100b In Preterm Infants, Elie G. Abu Jawdeh, Linda J. Van Eldik, Jennifer Stevenson, Abhijit Patwardhan, Philip M. Westgate, Lina Chalak, Richard J. Martin, Henrietta S. Bada

Epidemiology and Environmental Health Faculty Publications

Nitrogenated Graphene Quantum Dot-Derived Copper Single-Atom Catalyst For Oxygen Reduction Reaction, Dawatage Shashika Madushani Perera, Prakhar Sharma, Ayanthi Thisera, Nadeesha Kothalawala, Matthew G. Boebinger, Beth S. Guiton, Doo Young Kim

Chemistry Faculty Publications

Interface-Directed Synthesis Of Cspbbr3-Based Particles With Water-Ode Antisolvent Systems, Saurabh Singh, Xiyu Wen, Fuqian Yang

Chemical and Materials Engineering Faculty Publications

Influence Of Film Formation Kinetics On The Dispersion Of Colloidal Quantum Dots In Organic Small Molecule Matrices, Rachel C. Kilbride, Michael P. Weir, James Xiao, Simon A. Dowland, Jurjen F. Winkel, John E. Anthony, Akshay Rao, Richard A.L. Jones, Anthony J. Ryan, Daniel T.W. Toolan

Chemistry Faculty Publications

Stress-Induced Bandgap Modulation In Semiconductor Quantum Wells, Saurabh Singh, Fuqian Yang

Chemical and Materials Engineering Faculty Publications

Renin-Angiotensin-Aldosterone System In Preeclampsia: Pathophysiological Insights And Links To Vascular Dementia, Robin C. Finch, Jenny Lutshumba, Elizabeth Mirsky, Esther Ndashaala, Kelsey Bullens, Emma Smith

Pediatrics Faculty Publications

Neurology Faculty Publications

Markey Cancer Center Faculty Publications

Holographic Duality From Howe Duality, Anatoly Dymarsky, Johan Henriksson, Brian Mcpeak

Physics and Astronomy Faculty Publications

Human Atrial Skinned Muscle Fibers Exhibit Reduced Length-Dependent Activation But Show Faster Force Development Kinetics Than Ventricular Muscle, Alexandre Lewalle, Gregory Milburn, Jania Bell, Kenneth S. Campbell, Steven A. Niederer

Physiology Faculty Publications

Anthropology Faculty Publications

Neurology Faculty Publications