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Synthesis, Functionalization, And Application Of Polymeric Membrane Blends Of Polysulfone, Poly-Ether Ether-Ketone, And Natural Fiber Additive Biochar For Optimal Water Treatment., Abelline Katusiime Fionah

Theses and Dissertations--Chemistry

According to the Center for disease control (CDC), an estimated 1.7 to 2.2 million persons die from waterborne diseases annually. The majority of individuals dying from diseases resulting from unsafe drinking water, such as diarrhea and gastroenteritis, are children. This has in turn created a global water crisis. Different methods have been developed to treat contaminated water in response to the global water crisis such as adsorption, filtration, ozonolysis, catalysis, etc. Of the methods available, filtration via polymeric membranes has been one of the most successfully applied. A membrane is a thin semi-permeable barrier (often made of a polymer) used …

Stability Of Organic Metal Halide Perovskites, S S M Tareq Hossain

Theses and Dissertations--Chemistry

Perovskites have emerged as a promising candidate for low-cost production of solar cells. However, the most critical barrier for commercialization of perovskite solar cells (PSCs) is the inadequate stability of the organic metal halide perovskites (OMHPs). The degradation of OMHPs is induced by light, heat, air, and electrical bias. The known degradation pathways involve the oxidation of I- and Sn2+, dissolution of perovskites by moisture, irreversible reactions with water, ion migration, and ion segregation. To improve the stability of OMHPs various methods are adopted, such as additive engineering, perovskite surface treatment, and composition engineering. Surface ligands are used on top …

Fundamental Studies Of Optical Properties And Electrocatalytic Properties Of Low Dimensional Nanomaterials Carbon Nano Dots And 2d Transition Metal Dichalcogenides, Nadeesha Kothalawala

Theses and Dissertations--Chemistry

Low dimensional nanomaterials are widely used in a variety of applications such as opto-electronics, energy production and storage, and bio-medical applications due to their unique optical, catalytic, electronic, and mechanical properties. Most of the nanomaterials offer a plethora of modifications in their structure, composition, morphology, and dimensionality that can lead to the manipulation of their physiochemical properties. This dissertation presents insight into two types of compelling nanomaterials: carbon nanodots (CND) and transition metal dichalcogenides (TMD), investigating their optical and electrocatalytic properties respectively.

Carbon nanodots (CND) are a promising class of photoluminescent nanomaterials that hold a significant potential in many optoelectronic …

Investigating The Behavior Of Redox–Active Organic Molecules In Electrochemical Energy Storage Through Experiment–Guided Computational Simulations, Anton Perera

Theses and Dissertations--Chemistry

The long–anticipated implementation of using renewable sources such as solar and wind to meet the world’s energy demand is still limited by not having appropriate grid–level energy storage systems on a global scale. When considering grid–scale energy storage solutions, environmental concerns, and techno–economic viability play a crucial role in the practical implementation of such technology. To address this, redox–active organic molecules (ROMs) have been explored for many uses including serving as redox–active molecules in redox flow batteries (RFBs) and providing overcharge protection in lithium–ion batteries (LIBs).

Nevertheless, in order to be a major player in electrochemical energy storage, further optimization …

Impacts Of Key Degradation Byproducts On Amine Scrubbing For Post-Combustion Carbon Capture, Thomas Jorgensen

Theses and Dissertations--Chemistry

The increasing atmospheric CO₂ concentration causes significant concern about global warming and its environmental impact. Industrial sectors, including power generation, transportation, and production factories, contribute most of the anthropogenic sources of CO₂ emissions. Researchers search for methods to mitigate these CO₂ emissions without compromising the benefits of industrial processes, including CO₂ capture, utilization, and sequestration (CCUS). Post-combustion carbon capture (PCCC) by amine scrubbing is the most technology ready CCUS, with various pilot-scale projects worldwide showing small-scale to fully operational plants. While researchers have made significant progress in amine scrubbing, they strive to improve the efficiency and …

Noninvasive Freshness Evaluation Of Bighead Carp Heads Based On Fluorescence Spectroscopy Coupled With Long Short-Term Memory Network, Juan You, Zhenqian Sun, Xiaoting Li, Xiaoguo Ying, Ce Shi, Hongbing Fan

Animal and Food Sciences Faculty Publications

To swiftly and noninvasively assess the freshness of bighead carp heads within simulated cold chain environments, an excitation-emission matrix fluorescence spectroscopy coupled with a long short-term memory network (EEM-LSTM) model was developed. Through the parallel factor algorithm based on analysis of residuals, diagnosis of core consistency, and split-half evaluation, three key fluorescent components from fish fillets were extracted, with the most significant components linked to tryptophan and NADH, both indicative of fish freshness. The EEM-LSTM model exhibited coherent trends in freshness indicators and demonstrated exceptional predictive capabilities for four freshness indicators simultaneously, achieving R² values exceeding 0.8840 in simulated …

Role Of Ε-Poly-Lysine In Mixed Surimi Gel, Zhaorui Li, Guangcan Liang, Yungang Cao, Fang Yuan, Miaomiao Liu, Zelong Liu, Youling L. Xiong

Animal and Food Sciences Faculty Publications

The effects of different concentrations of ε-Poly-lysine (ε-PL: 0.005%, 0.01%, 0.02%, 0.04%, and 0.06%) on the marine fish-egg white protein compound gels, treated with 0.4% TGase induced cross-linking were systematically investigated under low salt and phosphorus-free conditions (0.5% NaCl). The results showed the combination of ε-PL and TGase had a synergistic effect on improving sectional gel properties of composite surimi samples. Wherein the rheological, LF-NMR, and SEM results confirmed that the addition of ε-PL based on 0.4% TGase significantly improved the gel strength (to the highest value: 781.63 g·cm), apparent viscosity, and G 'value of the composite surimi sample, as …

The 1-Back Matching/Mismatching Paradigm With Pigeons (Columba Livia): Evidence For Explicit Learning?, Daniel Peng

Theses and Dissertations--Psychology

With humans, a distinction can be made between explicit and implicit learning. language can be used to describe rule-based learning commonly seen in explicit, but not implicit learning. Unfortunately, we cannot do so with animals. Therefore, a non-verbal paradigm is needed to differentiate the types of learning. One method to make such a distinction is by training animals under a conditional discrimination task such as matching-to-sample with reinforcement delayed until a choice is made on the next trial: otherwise known as a 1-back procedure. In this experiment an alternating matching/mismatching to sample task under a 1-back schedule of reinforcement was …

Power Of Perception: The Role Of Perceived Caregiver Mindset Beliefs On Undergraduate Student Academic Engagement, Katherine R. Tanaka

Theses and Dissertations--Psychology

Promoting academic engagement is vital for college student success. Researchers have explored factors like growth mindset, the belief that intelligence can improve with effort, as a driver of academic engagement. Beyond personal mindset, students’ perceptions of key social influences, such as caregivers, also play a role. This study examined how undergraduate students’ own mindsets and perceptions of their caregivers’ mindsets relate to four components of academic engagement: behavioral and emotional engagement, and behavioral and emotional disaffection. Data from undergraduates (N = 1417) were analyzed using surveys, descriptive statistics, hierarchical regression, and exploratory moderation. Students generally reported both a personal …

Assessing Reliability For Quantifying Social Interactions Among Crayfish, Lee Ann Smith, Jeremy Nadolski, Grace Jacobs, Jodi M. Ogle, Madhusudan P. Srinivasan, Hannah N. Tanner, Elizabeth R. Steele, Nicole T. Marguerite, Sonya Bierbower, Slane Steen, Isaac Easterling, Abigail Greenhalgh, Cecilia Pankau, Shelby Mccubbin, Brad Behymer, Robin L. Cooper

Psychology Faculty Publications

Animal behavior is a useful way to evaluate the environment and can be a predictive tool to assess not only the effects of treatments in a laboratory setting, but also the status of ecological habitats. As invasive species of crayfish encroach on territories of native species, the social behaviors and interactions can be informative for ecological studies. For a wider and more impactful effect, training community scientists using a scoring system to record the social interactions of crayfish that includes both the level of aggression and intensity would provide useable data to monitor the environment. Amateur scientists with little training …

Biomechanics, Strength, And Physical Function After Surgical Repair Of Rotational Ankle Fractures, Benjamin Brightwell

Theses and Dissertations--Kinesiology and Health Promotion

Ankle Fractures account for approximately 9% of all lower extremity fractures and incidence continues to rise. Up to 53% of ankle fractures require surgical intervention. Impaired physical function is one of the most reported and observed lasting effects of surgically repaired ankle fractures. Additionally, limited physical capacity and function have been identified as the primary threats to health-related quality of life after surgical repair of ankle fractures. These impairments to physical capacity and functionality can last longer than 5 years after surgery. Since surgery typically successfully restores stability and congruency of the talocrural joint, these poor long-term outcomes are an …

Reimagining A Caregiver-Friendly Society, Jodi L. Southerland

Journal of Appalachian Health

Demographic aging is accelerating in the Appalachian Region, resulting in a growing proportion of caregivers living in areas that lack services to support their needs. Strategies are urgently needed in Appalachia to address deficiencies in the region’s long-term supports and services for older adults and their caregivers. Strengthening equitable access to care and community supports for family caregivers is a policy priority for state and community leaders in Appalachia.

Impact Of Fertilizer Type, Seed Coating, And Duration Of Exposure On The Germination Of Orchardgrass Seed, Edwin L. Ritchey, Christopher D. Teutsch

IGC Proceedings (1977-2023)

Cool-season grasses such as orchardgrass, are important components of forage systems in transition zone states like Kentucky. To maintain dense and vigorous sods, improved cool-season grass varieties are sometimes overseeded into existing stands in late-winter or early-spring. In many cases seed is mixed with fertilizer and top-dressed onto pastures. Little data are available on the impact of fertilizer type or duration of exposure on the germination of raw and coated grass seed. The objective of this study was to evaluate the impact of two fertilizer types, muriate of potash and a blended fertilizer (urea, diammonium phosphate, and muriate of potash), …

Beyond N-Dopants For Organic Semiconductors: Use Of Bibenzo[D]Imidazoles In Uv-Promoted Dehalogenation Reactions Of Organic Halides, Kan Tang, Megan R. Brown, Chad Risko, Melissa K. Gish, Garry Rumbles, Phuc H. Pham, Oana R. Luca, Stephen Barlow, Seth R. Marder

UK CARES Faculty Publications

2,2’-Bis(4-dimethylaminophenyl)- and 2,2'-dicyclohexyl-1,1',3,3'-tetramethyl-2,2',3,3'-tetrahydro-2,2'-bibenzo[d]imidazole ((N-DMBI)2 and (Cyc-DMBI)2) are quite strong reductants with effective potentials of ca. −2 V vs ferrocenium/ferrocene, yet are relatively stable to air due to the coupling of redox and bond-breaking processes. Here, we examine their use in accomplishing electron transfer-induced bond-cleavage reactions, specifically dehalogenations. The dimers reduce halides that have reduction potentials less cathodic than ca. −2 V vs ferrocenium/ferrocene, especially under UV photoexcitation (using a 365 nm LED). In the case of benzyl halides, the products are bibenzyl derivatives, whereas aryl halides are reduced to the corresponding arenes. The potentials of the halides that can be …

A Comparison Of Devices For Race Day Characterization Of North American Turfgrass Thoroughbred Racing Surfaces, Peter Schmitt, Wayne T. Sanderson, John Trey Rogers Iii, Tyler J. Barzee, Michael L. Peterson

UK CARES Faculty Publications

Both pre-race meet and daily turf surface condition measurements are required by regula- tions adopted as part of the Horseracing Integrity and Safety Act (HISA). The Orono Biomechanical Surface Tester (OBST) is the primary device used for characterizing a racing surface and is used for the pre-meet inspections. Tools that are better suited for the daily testing of turf surfaces are also needed to meet the new federal regulations. The purpose of this study was to compare five simple tools commonly used in turf applications to the OBST. Data were collected with each of the six devices at plots chosen …

A Wearable Fluorescence Imaging Device For Intraoperative Identification Of Human Brain Tumors, Mehrana Mohtasebi, Chong Huang, Mingjun Zhao, Siavash Mazdeyasna, Xuhui Liu, Samaneh Rabienia Haratbar, Faraneh Fathi, Jinghong Sun, Thomas A. Pittman, Guoqiang Yu

Biomedical Engineering Faculty Publications

Malignant glioma (MG) is the most common type of primary malignant brain tumors. Surgical resection of MG remains the cornerstone of therapy and the extent of resection correlates with patient survival. A limiting factor for resection, however, is the difficulty in differentiating the tumor from normal tissue during surgery. Fluorescence imaging is an emerging technique for real-time intraoperative visualization of MGs and their boundaries. However, most clinical grade neurosurgical operative microscopes with fluorescence imaging ability are hampered by low adoption rates due to high cost, limited portability, limited operation flexibility, and lack of skilled professionals with technical knowledge. To overcome …

Molecular Control Of Triplet-Pair Spin Polarization And Its Optoelectronic Magnetic Resonance Probes, Obadiah G. Reid, Justin C. Johnson, Joel D. Eaves, Niels H. Damrauer, John E. Anthony

Chemical and Materials Engineering Faculty Publications

Preparing and manipulating pure magnetic states in molecular systems are the key initial requirements for harnessing the power of synthetic chemistry to drive practical quantum sensing and computing technologies. One route for achieving the requisite higher spin states in organic systems exploits the phenomenon of singlet fission, which produces pairs of triplet excited states from initially photoexcited singlets in molecular assemblies with multiple chromophores. The resulting spin states are characterized by total spin (quintet, triplet, or singlet) and its projection onto a specified molecular or magnetic field axis. These excited states are typically highly polarized but exhibit an impure spin …

Deficiency Of Acute-Phase Serum Amyloid A Exacerbates Sepsis-Induced Mortality And Lung Injury In Mice, Ailing Ji, Andrea C. Trumbauer, Victoria P. Noffsinger, Luke W. Meredith, Brittany Dong, Qian Wang, Ling Guo, Xiangan Li, Frederick C. De Beer, Nancy R. Webb, Lisa R. Tannock, Marlene E. Starr, Christopher M. Waters, Preetha Shridas

Saha Cardiovascular Research Center Faculty Publications

Serum amyloid A (SAA) is a family of proteins, the plasma levels of which may increase >1000-fold in acute inflammatory states. We investigated the role of SAA in sepsis using mice deficient in all three acute-phase SAA isoforms (SAA-TKO). SAA deficiency significantly increased mortality rates in the three experimental sepsis mouse models: cecal ligation and puncture (CLP), cecal slurry (CS) injection, and lipopolysaccharide (LPS) treatments. SAA-TKO mice had exacerbated lung pathology compared to wild-type (WT) mice after CLP. A bulk RNA sequencing performed on lung tissues excised 24 h after CLP indicated significant enrichment in the expression of genes associated …

On The Origin And Evolution Of The Mosquito Male-Determining Factor Nix, James K. Biedler, Azedah Aryan, Yumin Qi, Aihua Wang, Ellen O. Martinson, Daniel A. Hartman, Fan Yang, Atashi Sharma, Katherine S. Morton, Mark Potters, Chujia Chen, Stephen L. Dobson, Gregory D. Ebel, Rebekah C. Kadling, Sally Paulson, Rui-De Xue, Michael R. Strand, Zhijian Tu

Entomology Faculty Publications

The mosquito family Culicidae is divided into 2 subfamilies named the Culicinae and Anophelinae. Nix, the dominant male-determining factor, has only been found in the culicines Aedes aegypti and Aedes albopictus, 2 important arboviral vectors that belong to the subgenus Stegomyia. Here we performed sex-specific whole-genome sequencing and RNAseq of divergent mosquito species and explored additional male-inclusive datasets to investigate the distribution of Nix. Except for the Culex genus, Nix homologs were found in all species surveyed from the Culicinae subfamily, including 12 additional species from 3 highly divergent tribes comprising 4 genera, suggesting Nix originated at least 133 to …

Magnetic Resonance Imaging Of Macrophage Response To Radiation Therapy, Harrison Yang, Brock Howerton, Logan Brown, Tadahide Izumi, Dennis C. Cheek, Jason Anthony Brandon, Francesc Marti, Roberto Gedaly, Reuben Adatorwovor, Fanny Chapelin

Markey Cancer Center Faculty Publications

Background: Magnetic resonance imaging (MRI) is a non-invasive imaging modality which, in conjunction with biopsies, provide a qualitative assessment of tumor response to treatment. Intravenous injection of contrast agents such as fluorine (19F) nanoemulsions labels systemic macrophages, which can, then, be tracked in real time with MRI. This method can provide quantifiable insights into the behavior of tumor-associated macrophages (TAMs) in the tumor microenvironment and macrophage recruitment during therapy.

Methods: Female mice received mammary fat pad injections of murine breast or colon cancer cell lines. The mice then received an intravenous 19F nanoemulsion injection, followed by a baseline 19F MRI. …

Design And Characterization Of A Novel Eef2k Degrader With Potent Therapeutic Efficacy Against Triple-Negative Breast Cancer, Changxin Zhong, Rongfeng Zhu, Ting Jiang, Sheng Tian, Xiaobao Zhao, Xiaoya Wan, Shilong Jiang, Zonglin Chen, Rong Gong, Linhao He, Jin-Ming Yang, Na Ye, Yan Cheng

Markey Cancer Center Faculty Publications

Dysregulated eEF2K expression is implicated in the pathogenesis of many human cancers, including triple-negative breast cancer (TNBC), making it a plausible therapeutic target. However, specific eEF2K inhibitors with potent anti-cancer activity have not been available so far. Targeted protein degradation has emerged as a new strategy for drug discovery. In this study, a novel small molecule chemical is designed and synthesized, named as compound C1, which shows potent activity in degrading eEF2K. C1 selectively binds to F8, L10, R144, C146, E229, and Y236 of the eEF2K protein and promotes its proteasomal degradation by increasing the interaction between eEF2K and the …

A Novel Tractor Operated Grass Seed Harvester Developed In India, Chandra Shekhar Sahay, D. S. Thorat, P. S. Pathak

IGC Proceedings (1977-2023)

The demand of green and dry fodder in India is estimated to increase to 1170 and 650 m tonne whereas availability is expected to be at 411.3 and 488 m tonne in 2025, respectively, depicting deficit of about 64.9% green fodder and 24.9% dry fodder (Vision 2030, ICAR - IGFRI, Jhansi, 2011). In forages, availability of quality seed is only 25-30% in cultivated fodder and less than 10 % in range grasses and legumes (Vision 2050, IGFRI). Prices paid for grass seeds of native species vary from Rs.5,000 to 6,500 per kg for clean, un-haired seeds due to excessive use …

Cattle Diet Composition Under A Short- Duration Grazing With And Without Deferment In Puna Rangelands, R. E. Tácuna, E. R. Flores

IGC Proceedings (1977-2023)

The treatments of rest and deferment periods have shown to be effective tools to improve range condition, but little is known about their effect on the diet of animals. The present research aimed to evaluate the effect of the deferment period when applied to a short-term grazing system. The experimental design was a completely random factorial where the treatments resulted from combination of two grazing management systems: short-duration with deferment period (WD) and no deferral period (ND) both evaluated for three years. Forage yield (4.9 vs. 4.5 Tm DM ha^-1 year^-1) like range condition (55.5 vs. 50.7%) …

Impact Of Fertilizer Type, Seeding Coating, And Duration Of Exposure On The Germination Of Red Clover Seed, C. D. Teutsch, Edwin L. Ritchey

IGC Proceedings (1977-2023)

Legumes are important components in grassland ecosystems. Red clover is one the most used legumes in the transition zones states like Kentucky. To maintain legumes in grass pastures, improved red clover varieties are often overseeded in the late-winter or early-spring. In many cases seed is mixed with fertilizer and top-dressed onto pastures. Little data are available on the impact of fertilizer type or duration of exposure on the germination of raw and coated red clover seed. The objective of this study was to evaluate the impact of two fertilizer types, muriate of potash and a blended fertilizer (urea, diammonium phosphate, …

Ecologically-Based Rodent Pest Management: Research Progress In Plateau Zokors On Qinghai-Tibetan Plateau, Su Junhu, Kang Yukun

IGC Proceedings (1977-2023)

Rodent management has been an ongoing global challenge. The emergence of ecologically based rodent management (EBRM) has improved a series of dilemmas in traditional rodent control that are poorly targeted, unsustainable, and environmentally harmful. The plateau zokor (Eospalax baileyi) is a key species in the Qinghai-Tibetan Plateau (QTP). In recent years, due to its high population density, this subterranean rodent has caused serious damage to the grassland ecosystems on the QTP. Currently, a series of explorations of EBRM on plateau zokors have been initiated. We review progress about EBRM on plateau zokor in this paper, which mainly includes …

Nutrient Balances Of Rewetted Fens – Groundwater Lysimeter Results, J. Hoysagk, M. Pesch, F. Eulenstein, A. Behrendt

IGC Proceedings (1977-2023)

With the raising of groundwater levels to protect fens and the climate, there may be a risk of nutrients, such as nitrogen or potassium, leaching into the groundwater. Great amounts of nutrients, which are accumulated largely by peat forming plants like Phragmites australis and Carex spec., are conveyed into rewetted fens through high amounts of introduced water. Nitrogen leaching into the groundwater is very low even at the beginning of flooding and there is no sudden, pronounced leaching. Only a portion of potassium is taken up by plants whereas the rest might be found in the groundwater. Increasing nutrient inputs …

Enclosure Rather Than Topography Enhances The Soil Ecological Stoichiometry In Typical Steppe On The Loess Plateau, China, Zhaoxia Guo, Fujiang Hou, Jiao Ning

IGC Proceedings (1977-2023)

Grassland is one of the largest terrestrial ecosystems in the world, a large part of which is distributed in varied topography. And grazing and enclosure are the main ways to use this part. Grazing changes the soil structure through feeding, trampling and excreta return, thus affects the soil nutrients. The aspect mainly affects soil temperature and moisture by affecting solar radiation. The slope affects soil nutrients by affecting surface runoff. Water and temperature are the main factors affecting soil nutrients. We carried out to explore the effect of enclosure years and topography on soil ecological stoichiometry. The results showed that: …

Forage Response And Economic Benefits To Weed Management In Grasslands, E. S. Flynn, S. Ingram, B. B. Sleugh

IGC Proceedings (1977-2023)

A common question among managers of grazing operations is “At what level of weed pressure does it become economical to apply herbicides on pastures?” Unfortunately, there isn’t just one answer to this question as production goals and practices differ between operations and even within an operation over time. Regardless, the real question being ask is if weed control will increase profit per acre.

There are three basic avenues that may be taken to improve profit per acre through weed control. The first is to increase the carrying capacity of the grazing operation by controlling weeds and replacing them with desirable …

Opening Speech, Ray Smith

IGC Proceedings (1977-2023)

https://youtu.be/CbRcQzf5z0o?si=ESOHxXF-jFsYMw2A

Chain Conformation And Exciton Delocalization In A Push-Pull Conjugated Polymer, Yulong Zheng, Rahul Venkatesh, Connor P. Callaway, Campbell Viersen, Kehinde H. Fagbohungbe, Aaron L. Liu, Chad Risko, Elsa Reichmanis, Carlos Silva-AcuñA

UK CARES Faculty Publications

Linear and nonlinear optical line shapes reveal details of excitonic structure in polymer semiconductors. We implement absorption, photoluminescence, and transient absorption spectroscopies in DPP-DTT, an electron push−pull copolymer, to explore the relationship between their spectral line shapes and chain conformation, deduced from resonance Raman spectroscopy and from ab initio calculations. The viscosity of precursor polymer solutions before film casting displays a transition that suggests gel formation above a critical concentration. Upon crossing this viscosity deflection concentration, the line shape analysis of the absorption spectra within a photophysical aggregate model reveals a gradual increase in interchain excitonic coupling. We also observe …