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Role Of Serum Amyloid A In Abdominal Aortic Aneurysm And Related Cardiovascular Diseases, Preetha Shridas, Avery C. Patrick, Lisa R. Tannock

Internal Medicine Faculty Publications

Epidemiological data positively correlate plasma serum amyloid A (SAA) levels with cardiovascular disease severity and mortality. Studies by several investigators have indicated a causal role for SAA in the development of atherosclerosis in animal models. Suppression of SAA attenuates the development of angiotensin II (AngII)-induced abdominal aortic aneurysm (AAA) formation in mice. Thus, SAA is not just a marker for cardiovascular disease (CVD) development, but it is a key player. However, to consider SAA as a therapeutic target for these diseases, the pathway leading to its involvement needs to be understood. This review provides a brief description of the pathobiological …

Structural Stability Of Short Latency Alfalfa-Based Pastures In The Humid Pampa, Argentina, R. O. Refi, B. Martín

IGC Proceedings (1977-2023)

The aim of this study was to search the effects of grazing intensity and nitrogen fertilization on the structural stability of a mixed pasture composed by alfalfa (latency group 9), brome grass, tall fescue and white clover, sown in April 1997. Rotational grazing was carried out with dairy cattle with high intensity (HI: up to 3-4 cm) or moderate intensity (LI: up to 8-10 cm), whenever the alfalfa showed basal regrowth. According to a split-plot design, grazing intensities were subdivided to assign three levels of nitrogen fertilization: N0, without fertilization; N1 with 50 kg N/ha per year; and N2 with …

Late Winter Dietary Overlap Among Greater Rheas And Domestic Herbivores On The Argentinean Flooding Pampa, G. Vacarezza, M. S. Cid, F. Milano

IGC Proceedings (1977-2023)

This study evaluates the dietary overlap among greater rheas (Rhea americana L.) sheep and cattle in the Flooding Pampa, Buenos Aires, Argentina during late winter, when is observed the lowest forage availability. The work was carried out with the following forage classes (FC): warm and cool season grasses and forbs (legumes and no-legumes). Diet botanical composition was estimated by microanalysis of faeces. Principal Component Analysis and Kulcyznsky´s index of similarity were used for data analysis. Rhea populations selected diets with higher forb percentages. On the contrary, vegetation structure and their own morpho-physiology conditioned cattle to diets almost exclusively gramineous. …

Beef Calf Production Using Year-Round Grazing On Tropical Grass Pasture In Summer Combined With Cool Temperate Grass Pasture In Winter, Y. Nakanishi, K. Shindou, S. Watanabe, K. Yamamoto, K. Hagino

IGC Proceedings (1977-2023)

Bahiagrass (Paspalum notatum Fluegge) showed a poor quality with low crude protein in summer but blood biochemical levels of grazing beef cows were similar to drylot feeding cows except of concentration of urea nitrogen. Italian ryegrass (Lolium multiflorum Lam) showed very good quality with high crude protein (about 20 percentage) in winter. And so, suckler cows gained live weight in winter and suckling calves were showed very high growth rate (daily gain was about 1.0 kg). Total live weight gains of grazing cows were higher than those of drylot feeding cows. Postpartum reproductive performances of grazing cows were …

Winter Grazing And Feeding Systems In Western Canada, Duane H. Mccartney, V. Baron, J. Basarab, E. Okine, G. Lastiwka, A. Depalme, D. Young

IGC Proceedings (1977-2023)

Beef cow calf producers in Western Canada are looking for methods of extending the grazing season into the winter in order to lower winter feed costs. Dry beef cows were early or late weaned and grazed during the early months of winter on late seeded barley swaths (Hardlum vulgare L.) and compared to cows fed barley silage and free choice barley straw in a feeding yard. The swath grazed barley was late seeded in June and swathed in the silage stage in mid September. Cows successfully swath grazed for three winters from mid November until mid to late February …

Forage Management For Extending The Grazing Season, David W. Koch, C. M. Lux, J. W. Flake

IGC Proceedings (1977-2023)

Studies were conducted to determine ways to extend grazing season with forages adequate to meet the needs of grazing animals and to reduce the cost of livestock production. Perennial grasses were swathed, windrowed and left in the field until they were winter-grazed with bred heifers. Corn (Zea mays L.) was stockpiled for winter grazing with lambs and ewes. Windrowed grasses increased in acid detergent fiber (ADF) and neutral detergent fiber (NDF) compared with stored hay, but crude protein content, heifer weight gain and body condition change was similar for both forages. An economic value of $218 ha^-1 from …

Biodiversity And Fire In Shortgrass Steppe, Paulette L. Ford

IGC Proceedings (1977-2023)

Effects of fire at two levels of intensity on beetle diversity in shortgrass steppe were examined. The experimental design was completely randomized, with 3 treatments and 4 replicates per treatment. Treatments were two levels of fire 1) dormant-season fire (relatively hot), and 2) growing-season fire (relatively cool), and unburned plots. The response variables were arthropod species richness and abundance. The intermediate disturbance hypothesis predicts that maximum species richness occurs at intermediate levels of disturbance. Data obtained in this study support that prediction. Species richness was higher on plots of intermediate fire intensity than the more intensely burned plots, and almost …

Mechanization: Planning And Selection Of Equipment, C. A. Rotz

IGC Proceedings (1977-2023)

The planning and selection of equipment for harvest and handling of forage crops can greatly impact the performance and profitability of a farm. The type and size of equipment used affects the harvested yield and nutritive value of the forage crop as well as production costs. Through interactions with other parts of the farm, these effects can impact market value of the forage, animal intake and performance, delays in other farm operations, other production costs, and ultimately farm profit. Standard procedures and relationships have been developed for determining the most appropriate equipment for a given production system. Because of the …

Conserved Forage (Silage And Hay): Progress And Priorities, R. E. Muck, K. J. Shinners

IGC Proceedings (1977-2023)

Forage conservation permits a better supply of quality feed when forage production is low. While haymaking and ensiling have been practiced for generations, research is still needed to 1) understand the processes affecting quality during harvesting and storage and 2) develop practical means to minimize losses and enhance quality.

Several trends in harvesting forages for silage are notable. Kernel processing of maize, once confined to Europe, has become popular in North America. Self-propelled forage harvesters have a larger share of the market due to more contract harvesting and larger farms. Larger harvesters, rakes and mergers help improve productivity and forage …

Comparison Of Quality And Production By Different Silage Making Methods Of Barley Cultivated In The Paddy After Rice Harvest, J. S. Shin, E. B. Yoon, M. S. Park

IGC Proceedings (1977-2023)

The objective of this study was to compare whether the productivity and production cost of whole crop barley was affected by silage making methods at early bloom stage in the rice field. In nutritive value, quality and palatability of silage, baled silage making method was a little higher than that of crushed silage making. On the other hand, in terms of dry matter and total digestible nutrient (TDN) production cost, proper work capacity at about 15 ha or more was desirable when making baled silage. In this case, the estimated dry matter production cost and TDN cost per ha was …

Yield, Feeding Value And Ensiling Characteristics Of Clone-13 (Pennisetum Purpureum), Sujatha Premaratne, G. G. C. Premalal, S. M. S. Setunga, J. M. S. Jayawardana

IGC Proceedings (1977-2023)

A study was carried out to find out the effect of frequency of defoliation on yield and feeding value of clone-13 (Pennisetum purpureum) in Sri Lanka. Three frequency of harvesting, namely 45, 60 and 75 days were used and, fresh yield per plot was measured. Sub samples were taken for dry matter determination and proximate analysis. According to results, frequency of harvesting of 60 days can be recommended for clone-13 under no fertilizer regime. In addition, effect of growth stage on ensiling characteristics of clone-13 was also studied. Clone-13 was harvested at 45, 60, 75 or 90 days …

Aerobic Stability Of Grass Silage Mixed With A Range Of Concentrate Feedstuffs At Feed-Out, P. O’Kiely, M. Clancy, E. M. Doyle

IGC Proceedings (1977-2023)

Mixing supplementary concentrates with silage at feed-out could shorten aerobic stability or increase the rate or extent of aerobic deterioration of silage. This experiment quantified such possible effects by twelve contrasting feedstuffs. Four samples (each 6 kg) of unwilted, precision-chop, well preserved grass silage (216 g dry matter (DM) kg^-1 and pH 4.0) were incubated at 20^oC for 6 days in polystyrene containers alone or with the addition of 400 g (solid ingredients were milled) of wheat grain, barley grain, maize grain, molasses beet pulp, citrus pulp, molasses, soybean meal, maize gluten, sunflower meal, rapeseed meal, dry …

Survival Of Escherichia Coli 0157:H7 Added To Grass At Ensiling And Its Influence On Silage Fermentation, P. O’Kiely, C. Byrne, D. Bolton

IGC Proceedings (1977-2023)

Escherichia coli can cause health problems in humans and livestock. It is frequently found in faeces and soil, both of which can contaminate grass harvested for silage-making. To determine the survival of E. coli 0157:H7 during ensilage, and its influence on ensilage, unwilted precision-chop grass was ensiled in laboratory silos with the following additive treatments: (a) no additive, (b) E. coli 0157:H7 (Ec - non-infectious strain, at log₁₀ 4.5 colony forming units (cfu) g^-1), formic acid (FA), and (d) Ec + FA. Silos were stored at 15^oC. Three silos per treatment were opened on days …

Total Synthesis Of Decahydroquinoline Poison Frog Alkaloids Ent-Cis-195a And Cis-211a, Takuya Okada, Naizhen Wu, Katsuki Takashima, Jungoh Ishimura, Hiroyuki Morita, Takuya Ito, Takeshi Kodama, Yuhei Yamasaki, Shin-Ichi Akanuma, Yoshiyuki Kubo, Ken-Ichi Hosoya, Hiroshi Tsuneki, Tsutomu Wada, Toshiyasu Sasaoka, Takahiro Shimizu, Hideki Sakai, Linda P. Dwoskin, Syed R. Hussaini, Ralph A. Saporito, Naoki Toyooka

Pharmaceutical Sciences Faculty Publications

The total synthesis of two decahydroquinoline poison frog alkaloids ent-cis-195A and cis-211A were achieved in 16 steps (38% overall yield) and 19 steps (31% overall yield), respectively, starting from known compound 1. Both alkaloids were synthesized from the common key intermediate 11 in a divergent fashion, and the absolute stereochemistry of natural cis-211A was determined to be 2R, 4aR, 5R, 6S, and 8aS. Interestingly, the absolute configuration of the parent decahydroquinoline nuclei of cis-211A was the mirror image of that …

Effects Of Dry Matter Content And Microbial Additive On Tifton 85 (Cynodon Dactylon Ssp.) Wilted Silage Fermentation Parameters, Luiz Gustavo Nussio, F. G. Castro, J. M. Simas, C. M. Haddad, P. Toledo, A. L. Merchan

IGC Proceedings (1977-2023)

The objective of this study was to evaluate the wilting and the addition of a bacterial-enzymatic additive effects on the fermentation parameters of Tifton 85 (Cynodon dactylon spp.) silage. Forage was stored as 326 kg bales wrapped with a plastic film. Treatments consisted of 5 forage dry matter levels (20-30%, 30-40%, 40-50%, 50 -60% e 60 a 70%) without additive and 3 dry matter levels (20-30%, 40-50%, e 60-70%) with additive. Buffered propionic acid solution was sprayed onto 60-70% dry matter bales, prior to wrapping, determining an additional treatment. Core samples were taken at 0, 6, 12 hours …

Dry Matter Losses In Tanzânia Grass (Panicum Maximum, Jacq, Cv. Tanzânia) Silage, M. A. A. Balsalobre, Luiz Gustavo Nussio, P. M. Santos, R. F. Crestana, R. N. S. Aguiar, M. Corsi

IGC Proceedings (1977-2023)

A spring cut of Tanzânia grass (Panicum maximum, Schum, cv. Tanzânia) was harvested (20% DM), in a 60-day regrowth sward. Laboratory silos (20 L) were filled with chopped forage. Nine treatments, in a 3 x 3 factorial arrangement with four replication each. Treatments consisted on the addition of 3 levels of dehydrated and pellet citrus pulp (CP) (0, 5 and 10%- fresh basis) combined with 3 particle sizes (Larger (1), medium (2) and smaller (3)). After 60 days silos were opened, effluent and gas yield was calculated. Reduction in particle size lowered gas losses in silage. Major benefit …

Possibilities To Avoid Growth Of Clostridia And/Or Fungi In Wilted Silage By Use Of Organic And Inorganic Salts, Martin Knický, P. Lingvall

IGC Proceedings (1977-2023)

The hygienic quality of silage will be of great importance in the future as poor quality not only influences the animal production but also the animal health and the food quality. This study examined the impact of mixtures of sodium benzoate (NaB), sodium nitrite (NaN), hexamine (HMTA), sodium propionate (NaP), sodium bisulphite, and propionic acid on low and high wilted clover/grass. The silage (crop wilted to 300 or 600 g DM kg^-1 of fresh weight) consisted of about 50% red clover (Trifolium pratense) and 50% timothy (Phleum pratense) and the study covered 7 additive treatments. …

An Assessment Of Grass Regeneration Nurseries At The Western Regional Plant Introduction Station, 1994-1997, V. L. Bradley, R. C. Johnson

IGC Proceedings (1977-2023)

The Western Regional Plant Introduction Station (WRPIS), Pullman, WA, USA, maintains over 17,000 accessions of forage and turf grasses that are mostly wind cross-pollinated and highly heterogenic. Regeneration procedures have been refined over the past nine years to include improved isolation distance and increased plant populations for regeneration. The grass regeneration nurseries planted from 1994 through 1997 were evaluated using data recorded in the Germplasm Resources Information Network (GRIN) and it was found that approximately 78% of the regenerations were successful. Reasons for failures were contributed to inadequate plant number, presence of disease, seed shattering, and unsuitable growing environment. Several …

Assessment Of Ensilability Of Six Tropical Grasses Using Three Different Approaches, B. Zierenberg, K. Friedel, A. Glatzle, A. Chudy

IGC Proceedings (1977-2023)

The preparation of well-preserved silages is considered increasingly important in the tropics and subtropics. In these regions silage production played a minor role in the past, as ensilability of tropical grasses is generally considered poor. In this study ensilability of six tropical grasses grown in the Paraguayan Chaco Boreal (Panicum maximum cv. Gatton, Cynodon plectostachyus, Cynodon sp. cv. Tifton 85, Digitaria eriantha var. pentzii, Panicum maximum cv. Tanzania and Digitaria milanjiana) was assessed in three different ways: (1) The chemical determination of the ratio between water soluble carbohydrates (WSC) and buffer capacity (BC), (2) the biological …

Improving The Feeding Value Of Cotton Stalk, Wheat Straw And Rice Straw With Ozonation, Meiji Okamoto, Masaaki Hanada, R. Aoyama, R. Kim, N. Kaiga

IGC Proceedings (1977-2023)

The experiment was conducted to study the effect of ozone treatment on the feed value of cotton stalk, wheat straw and rice straw. These feeds were cut into 2 cm and 4 cm lengths, and rolled before ozonizing. The ozonizing periods were 30 min. 60min and. 120 min. The Acid Detergent Lignin (ADL) concentration of the feeds decreased with ozone treatment. Except for rice straw, the short cutting treatment (2cm) decreased the concentration of ADL and Cellulose of the ozonized cotton stalk and wheat straw. Rolling and ozone treatment were effective in decreasing the ADL concentration of cotton stalk. IVDMD …

Fermentation Quality Of Phasey Bean And Guineagrass Silages, Y. Imura, T. Namihira, Yasuhiro Kawamoto

IGC Proceedings (1977-2023)

Silages were made from guineagrass (Panicum maximum Jacq. var. maximum) and phasey bean (Macroptilium lathyroides (L.) Urb.) at three-growth stages. The silages were investigated in relation fermentation quality. Phasey bean silage showed a better fermentation quality than guineagrass silage. The latic acid to total acid ratio of phasey bean silage was higher than 500g/kg DM, and the volatile basic nitrogen to total nitrogen ratio was lower than 100g/kg. It is concluded that phasey bean is an unique legume suitable for good silage fermentation.

Burning And Management Alternatives On Forage Accumulation And Floristic Composition Of A Native Pasture, I. Heringer, A. V. A. Jacques

IGC Proceedings (1977-2023)

The forage accumulation and floristic composition of native pasture, submitted to burning and alternative management practices, was evaluated during one year. The experimental design was a completely randomized, with five treatments and three replications. The forage accumulation was evaluated in a grazing exclusion cage, and the floristic composition was estimated with Botanal method. The systems without burning were more productive and, among these, the forage accumulation was similar between the one without burning and without mowing and the improve treatments, and the annual accumulation was greater than 9,000 Kg/ha of green forage dry matter. The species Paspalum notatum, P. …

Nitrogen Flow To Duodenum Of Steers Grazing On Orchardgrass And Meadowfescue Pastures, Masaaki Hanada, Y. Aibibula, Meiji Okamoto

IGC Proceedings (1977-2023)

This experiment was conducted to evaluate nitrogen flow to the duodenum of steers grazing on orchardgrass (Dactylis glomerata L., OG) or meadowfescue (Festuca elatior L., MF) pasture. Holstein steers fitted with cannulas in the rumen and duodenum were used. Nitrogen content and in vitro dry matter digestibility of herbage did not differ between OG and MF pastures. Herbage nitrogen intake of steers grazing on OG and MF pastures averaged 229 and 271 g/day, respectively. Nitrogen flows to the duodenum of steers grazing on orchardgrass and meadowfescue pastures averaged 187 and 195g/d, respectively. Microbial nitrogen flow to the duodenum …

The Effects Of Post-Grazing Sward Conditions On Herbage Accumulation In Winter And Spring, F. P. Hughes, P. N. P. Matthews, C. Matthew

IGC Proceedings (1977-2023)

Two on-farm experiments were conducted in the winter and spring of 1998 on a New Zealand seasonal production dairy farm to determine the effect of herbage mass present after grazing on subsequent pasture growth rates. Experiments involved a range of post-grazing levels of herbage mass (870, 1140, 1390, 1640, 1920 kg DM/ha in winter, and 1100, 1420, 1700 and 1910 kg DM/ha in spring) representing a range in cow intakes of 6.1-20.0 and 7.6-18.5 kg DM/cow/day in winter and spring, respectively. In both experiments there was a range of postgrazing herbage mass (1200-1600 kg DM/ha in winter and 1400-1800 kg …

Defining Disparities In Cochlear Implantation Through The Social Determinants Of Health, Marissa Schuh, Matthew L. Bush

Otolaryngology--Head & Neck Surgery Faculty Publications

Hearing loss is a global public health problem with high prevalence and profound impacts on health. Cochlear implantation (CI) is a well-established evidence-based treatment for hearing loss; however, there are significant disparities in utilization, access, and clinical outcomes among different populations. While variations in CI outcomes are influenced by innate biological differences, a wide array of social, environmental, and economic factors significantly impact optimal outcomes. These differences in hearing health are rooted in inequities of health-related socioeconomic resources. To define disparities and advance equity in CI, there is a pressing need to understand and target these social factors that influence …

Evidence Of Myomir Regulation Of The Pentose Phosphate Pathway During Mechanical Load-Induced Hypertrophy, Taylor Valentino, Vandre C. Figueiredo, C. Brooks Mobley, John J. Mccarthy, Ivan J. Vechetti Jr.

Physiology Faculty Publications

Many of the molecular and cellular mechanisms discovered to regulate skeletal muscle hypertrophy were first identified using the rodent synergist ablation model. This model reveals the intrinsic capability and necessary pathways of skeletal muscle growth in response to mechanical overload (MOV). Reminiscent of the rapid cellular growth observed with cancer, we hypothesized that in response to MOV, skeletal muscle would undergo metabolic programming to sustain increased demands to support hypertrophy. To test this hypothesis, we analyzed the gene expression of specific metabolic pathways taken from transcriptomic microarray data of a MOV time course. We found an upregulation of genes involved …

Spring Regrowth And Steer Performance On Tifton 85 And Coastal Bermudagrass Pastures Following Sod-Seeding With Ryegrass, G. M. Hill, R. N. Gates

IGC Proceedings (1977-2023)

Effects of autumn sod-seeded ryegrass (Lolium multiflorum; cv. Passerel; 37.7 kg/ha) in bermudagrass pastures (Cynodon spp.; cv. Coastal and cv. Tifton 85) on grazing steer performance were determined. Ryegrass was sod-seeded in three of six .81 ha pastures of each bermudagrass. Forage height was adjusted to10 cm during spring. Stocking rates were unaffected by ryegrass in Tifton 85 pastures, but they were higher (P < .05) for Tifton 85 than Coastal. Ryegrass increased tester steer average daily gains by 34% (.86 vs .64 kg/day; P < .01), and gain/ha by 26% (387 vs 306 kg/ha; P < .05). Higher stocking rates resulted in 22% more grazing days (515 vs 421 days/ha; P < .01), and 30% higher gain/ha (391 vs 301 kg/ha; P < .05) for Tifton 85 than Coastal pastures. Ryegrass did not affect stocking rates or steer performance on Tifton 85, but it depressed both on Coastal pastures.

Intensive Grazing Systems For Beef Cattle Production, F. P. Fontenot, V. G. Allen, M. A. Cochran, N. B. Frank

IGC Proceedings (1977-2023)

The objective of this study was to compare grazing systems that used rotational and continuous stocking for beef cows-calves and stocker cattle grazing fescue (Festuca arundinacea) and clover (Trifolium repens). For each system seven cows/calves and seven stocker steers were used within each of two replicates. The cows and stockers grazed stockpiled forage and were fed hay in winter, and grazed growing forage during spring and summer. Cows in the rotational system gained at a faster rate (P< . 05) from October to April than those in the continuous system. Daily gains of calves were higher (P< . 05) for the continuous system. Rate of gain during the last 28 days was higher (P< . 05) for the stockers in the rotational system. Average hay yields were not different for the two stocking systems, but more (P< . 05) hay was fed to the cattle in the continuous system. The system that used continuous stocking was more easily managed and required less labor and facilities.

Dementia Risk Reduction: Why Haven't The Pharmacological Risk Reduction Trials Worked? An In-Depth Exploration Of Seven Established Risk Factors, Ruth Peters, John Breitner, Sarah James, Gregory A. Jicha, Pierre-Francois Meyer, Marcus Richards, A. David Smith, Hussein N. Yassine, Erin L. Abner, Atticus H. Hainsworth, Patrick G. Kehoe, Nigel Beckett, Christopher Weber, Craig Anderson, Kaarin J. Anstey, Hiroko H. Dodge

Neurology Faculty Publications

Identifying the leading health and lifestyle factors for the risk of incident dementia and Alzheimer's disease has yet to translate to risk reduction. To understand why, we examined the discrepancies between observational and clinical trial evidence for seven modifiable risk factors: type 2 diabetes, dyslipidemia, hypertension, estrogens, inflammation, omega-3 fatty acids, and hyperhomocysteinemia. Sample heterogeneity and paucity of intervention details (dose, timing, formulation) were common themes. Epidemiological evidence is more mature for some interventions (eg, non-steroidal anti-inflammatory drugs [NSAIDs]) than others. Trial data are promising for anti-hypertensives and B vitamin supplementation. Taken together, these risk factors highlight a future need …

Evaluating And Enhancing Iron Removal Via Filterable Iron Precipitates Formation During Coal-Waste Bioleaching, Prasenjit Podder, Zongliang Zhang, Rick Q. Honaker, Michael L. Free, Prashant K. Sarswat

Mining Engineering Faculty Publications

Iron removal via jarosite precipitate formation is a commonly used technique in various hydrometallurgical processes. Excess iron removal often becomes essential to an overall metal recovery circuit. This is particularly important to processes involving iron-bearing minerals. A technique, which involved the use of pyrite to generate acid for leaching, for iron removal is critical to enabling the process. Iron removal using CaO or similar reagents is expensive and often results in lost product. In the present study, various compounds that facilitate jarosite formation, namely Na₂SO₄, NH₄OH, KCl, and KOH, were utilized and their effect …