Digital Commons Network^™

Using State And Local Health Survey Data To Advance Phssr, Glen P. Mays

Health Management and Policy Presentations

State and local health survey data can be used to evaluate the implementation and impact of public health delivery innovations in real-world practice settings.

Harnessing The Potential Of Comparative Effectiveness Research And Delivery System Innovation Through Practice-Based Research, Glen P. Mays

Health Management and Policy Presentations

Testing delivery system innovations in health care and public health allows the practice-based research enterprise to lead the way toward gains in health and economic efficiency.

Oral Microbial Biofilm Stimulation Of Epithelial Cell Responses, Rebecca Peyyala, Sreenatha S. Kirakodu, Karen F. Novak, Jeffrey L. Ebersole

Center for Oral Health Research Faculty Publications

Oral bacterial biofilms trigger chronic inflammatory responses in the host that can result in the tissue destructive events of periodontitis. However, the characteristics of the capacity of specific host cell types to respond to these biofilms remain ill-defined. This report describes the use of a novel model of bacterial biofilms to stimulate oral epithelial cells and profile select cytokines and chemokines that contribute to the local inflammatory environment in the periodontium. Monoinfection biofilms were developed with Streptococcus sanguinis, Streptococcus oralis, Streptococcus gordonii, Actinomyces naeslundii, Fusobacterium nucleatum, and Porphyromonas gingivalis on rigid gas-permeable contact lenses. Biofilms, as well as planktonic cultures …

Sustainable Agriculture Undergraduate Degree Programs: A Land-Grant University Mission, Krista L. Jacobsen, Kim L. Niewolny, Michelle S. Schroeder-Moreno, Mark Van Horn, Alison H. Harmon, Yolanda H. Chen Fanslow, Mark A. Williams, Damian Parr

Horticulture Faculty Publications

There has been considerable growth in the number undergraduate degree programs in sustainable agriculture (SA) in universities and colleges across the country in the past 25 years. As a subset of this national trend, land-grant universities (LGUs) are emerging as catalysts in innovative SA program development, in part due to the LGU tripartite mission of education, extension, and research. This mission compels LGUs to develop undergraduate degree offerings to engage student, faculty, and community stakeholders who are increasingly interested in SA. In this article, which is an outcome of a gathering of faculty, staff and students from SA programs at …

Sustainable Agriculture Education And Civic Engagement: The Significance Of Community-University Partnerships In The New Agricultural Paradigm, Kim L. Niewolny, Julie M. Grossman, Carmen J. Byker, Jennifer L. Helms, Susan F. Clark, Julie A. Cotton, Krista L. Jacobsen

Horticulture Faculty Publications

Universities and colleges across the United States are making innovative strides in higher education programming to catalyze a more sustainable era of agriculture. This is clearly exemplified through the formation of community-university partnerships as critical illustrations of civic engagement (CE) for sustainable agriculture (SA) education. This paper explores the praxis of CE for SA education by focusing on the ways in which five land-grant universities (LGUs) with undergraduate programs in SA have developed and put into practice community-university partnerships. Drawing upon these programs and supportive literature, this article specifically attempts to describe the role and significance of CE for SA …

Violence And Apocalypse In Ricardo Chávez Castañeda's El Día Del Hurón, Kristina Puotkalyte-Gurgel

Nomenclatura: aproximaciones a los estudios hispánicos

No abstract provided.

Inhibition Of Fatty Acid Synthase Attenuates Cd44-Associated Signaling And Reduces Metastasis In Colorectal Cancer, Yekaterina Y. Zaytseva, Piotr G. Rychahou, Pat Gulhati, Victoria Allison Elliott, William Conan Mustain, Kathleen O'Connor, Andrew J. Morris, Manjula Sunkara, Heidi L. Weiss, Eun Young Lee, B. Mark Evers

Markey Cancer Center Faculty Publications

Fatty acid synthase (FASN) and ATP-citrate lyase, key enzymes of de novo lipogenesis, are significantly upregulated and activated in many cancers and portend poor prognosis. Even though the role of lipogenesis in providing proliferative and survival advantages to cancer cells has been described, the impact of aberrant activation of lipogenic enzymes on cancer progression remains unknown. In this study, we found that elevated expression of FASN is associated with advanced stages of colorectal cancer (CRC) and liver metastasis, suggesting that it may play a role in progression of CRC to metastatic disease. Targeted inhibition of lipogenic enzymes abolished expression of …

Fibrinogen, Chronic Obstructive Pulmonary Disease (Copd) And Outcomes In Two United States Cohorts, Deepa Valvi, David M. Mannino, Hana Müllerova, Ruth Tal-Singer

Preventive Medicine and Environmental Health Faculty Publications

BACKGROUND: Fibrinogen is a marker of systemic inflammation and may be important in the pathogenesis and progression of chronic obstructive pulmonary disease (COPD).

METHODS: We used baseline data from Atherosclerosis Risk in Communities and Cardiovascular Health Studies to determine the relation between fibrinogen levels and COPD and to examine how fibrinogen levels at baseline affected outcomes of death, development of COPD, lung function decline, and COPD-hospitalizations.

RESULTS: Our study sample included 20,192 subjects, of whom 2995 died during the follow-up period. The mean fibrinogen level was 307.6 mg/dL and 10% of the sample had levels >393.0 mg/dL. Subjects with Stage …

Alteration Of Tobacco Alkaloid Content Through Modification Of Specific Cytochrome P450 Genes, Ralph E. Dewey, Balaz Siminszky, Steven W. Bowen, Lily Gavilano

Plant and Soil Sciences Faculty Patents

Compositions and methods for reducing the level of nornicotine and N′-nitrosonornicotine (NNN) in Nicotiana plants and plant parts thereof are provided. The compositions comprise isolated polynucleotides and polypeptides for cytochrome P450s that are involved in the metabolic conversion of nicotine to nornicotine in these plants. Expression cassettes, vectors, plants, and plant parts thereof comprising inhibitory sequences that target expression or function of the disclosed cytochrome P450 polypeptides are also provided. Methods for the use of these novel sequences to inhibit expression or function of cytochrome P450 polypeptides involved in this metabolic conversion are also provided. The methods find use in …

Farmer Panel--Managed Grazing And Profits, Bill Payne

Kentucky Alfalfa and Stored Forage Conference

Profits are the goal of any business model and mine is no exception. My plan assumes that available natural resources are efficiently utilized in a responsible manner.I have chosen to implement that plan by producing, managing and marketing our forage resources by utilizing Management Intensive Grazing (MIG.)

Role And Importance Of Alfalfa In Beef Diets, Jeff Lehmkuhler

Kentucky Alfalfa and Stored Forage Conference

Alfalfa is often referred to as the “Queen” of forage. Is this because of its high fertility needs and more finicky soil fertility needs along with greater management for optimal growth and persistency? Or is it because of it being on top of nearly all other forages for yield and quality? Truth be told, it is likely a combination of all these factors. Alfalfa is a versatile forage as it can be harvested for hay or silage and also grazed with proper management. For these reasons, this forage can fit well in beef operations.

Alfalfa Hay For Horses, Robert Coleman

Kentucky Alfalfa and Stored Forage Conference

When horse owners consider hay for their horses, a number of criteria are generally considered. Of major importance is the hay must be free of mold and dust. It needs to contain nutrients needed by the horse and it must be palatable. If these criteria are met, the type of hay should not matter. However, that is not the case with many horse owners. When discussing the selection of hay, many owners first consider the type of hay. Can it be alfalfa or should it be a grass or how about a mix of grass and a legume. If a …

Kentucky Department Of Agriculture Hay Testing Program, Kim Field

Kentucky Alfalfa and Stored Forage Conference

The Kentucky Department of Agriculture offers a forage testing service which provides nutritional and energy value information. A Kentucky Department of Agriculture staff member will take sample(s) of hay and/or haylage at the farm and analyze them in the Kentucky Department of Agriculture Forage Laboratory located in Frankfort. Tested forages can mean higher profit, whether feeding cattle, horses, goats, sheep or other livestock. By knowing the nutritional and energy value, you can minimize your cost and maximize your production.

Aluminum In Food – The Nature And Contribution Of Food Additives, Robert A. Yokel

Pharmaceutical Sciences Faculty Publications

No abstract provided.

Reducing Endophyte-Related Economic Losses, Don Ball

Forage Symposium at the Kentucky Cattlemen’s Convention

Tall fescue is native to Europe and was rarely planted in the United States until after the first four decades of the 20th century. However, since the release of the variety ‘Kentucky 31’ in 1943, this versatile cool season perennial grass has been widely planted for forage, turf, and conservation purposes, with most of the acreage planted consisting of this variety. “Fescue” has many attributes including wide adaptation, easy establishment, a long growing season, good forage and seed yield, and tolerance of a wide range of management conditions.

The Complete Mitochondrial Genome And Novel Gene Arrangement Of The Unique-Headed Bug Stenopirates Sp. (Hemiptera: Enicocephalidae), Hu Li, Hui Liu, Aimin Shi, Pavel Stys, Xuguo Zhou, Wanzhi Cai

Entomology Faculty Publications

Many of true bugs are important insect pests to cultivated crops and some are important vectors of human diseases, but few cladistic analyses have addressed relationships among the seven infraorders of Heteroptera. The Enicocephalomorpha and Nepomorpha are consider the basal groups of Heteroptera, but the basal-most lineage remains unresolved. Here we report the mitochondrial genome of the unique-headed bug Stenopirates sp., the first mitochondrial genome sequenced from Enicocephalomorpha. The Stenopirates sp. mitochondrial genome is a typical circular DNA molecule of 15, 384 bp in length, and contains 37 genes and a large non-coding fragment. The gene order differs substantially from …

Child Food Security And The Food Stamp Program: What A Difference A Month Makes, Yiran Li, Bradford Mills, George Davis, Elton Mykerezi

University of Kentucky Center for Poverty Research Discussion Paper Series

Most Americans believe that children should not have either persistent concerns about the quality and quantity of food to eat or lack of actual access to food due to low household resources. However, in 2007, approximately 3.3 million households (8.3 percent of households with children) had food insecure children who did not have consistent access to adequate and safe foods (Nord and Golla, 2009). This implies less than complete coverage of children by the food-assistance safety net.

The United States’s Supplemental Nutrition Assistance Program (SNAP), historically and commonly known as the Food Stamp Program (FSP), is a federal-assistance program designed …

Low Income Preschoolers' Non-Parental Care Experiences And Household Food Insecurity, Colleen Heflin, Irma Arteaga, Sara Gable

University of Kentucky Center for Poverty Research Discussion Paper Series

Rates of food insecurity in households with children have significantly increased over the past decade. The majority of children, including those at risk for food insecurity, participate in some form of non-parental child care during the preschool years. To evaluate the relationship between the two phenomenon, this study investigates the effects of child care arrangements on food insecurity in households with children. To address the selection bias problem that arises from the fact that enrollment in different types of child care is not a random process, this study uses propensity scores techniques. The authors compare outcomes across five child care …

Food Store Environment Modifies Intervention Effect On Fruit And Vegetable Intake Among Low-Income Women In North Carolina, Alison A. Gustafson, Joseph Sharkey, Carmen D. Samuel-Hodge, Jessica C. Jones-Smith, Jianwen Cai, Alice S. Ammerman

Dietetics and Human Nutrition Faculty Publications

Background. The aim of the study is to determine how the food store environment modifies the effects of an intervention on diet among low-income women. Study Design. A 16-week face-to-face behavioral weight loss intervention was delivered among low income midlife women. Methods. The retail food environment for all women was characterized by (1) the number and type of food stores within census tracts; (2) availability of healthy foods in stores where participants shop; (3) an aggregate score of self-reported availability of healthy foods in neighborhood and food stores. Statistical Analyses. Multivariable linear regression was used to …

Families With Hungry Children And The Transition From Preschool To Kindergarten, Colleen Heflin, Irma Arteaga, Sara Gable

University of Kentucky Center for Poverty Research Discussion Paper Series

This paper exploits a source of variation in the eligibility for federal nutrition programs to identify the program effects on food insecurity. Children are eligible for the WIC program until the day before they turn 61 months old. The result is an age discontinuity in program participation at the 61-month cutoff. Using the Early Childhood Longitudinal Study Birth-cohort dataset, we find strong evidence of a sizeable increase in household food insecurity at the 61- month cutoff. Our findings are robust to different model specifications, datasets, and various bandwidth choices using various non-parametric estimations.

Influence Of The Neotyphodium--Tall Fescue Symbiosis On Belowground Processes, D. H. Mcnear Jr., Rebecca L. Mcculley

Plant and Soil Sciences Faculty Publications

Much of the work to date on the relationships between cool season grasses and Neotyphodium fungal endophytes has focused on the physiological, biochemical, and genetic ramifications of the host-fungus relationship and the subsequent influence these effects have on ruminant nutrition, plant adaptation to environmental stresses, and aboveground ecological processes. Relatively little attention has been paid to effects on belowground parameters. In this paper, we review the research evaluating the impact of one endophyte-grass association, the Neotyphodium – tall fescue symbiosis, on underground ecological and biogeochemical processes. We also present some preliminary data showing that the quantity and nature of tall …

Privatization And Performance In The Implementation Of Temporary Assistance To Needy Families, Adam Michael Butz

Theses and Dissertations--Political Science

In response to the passage of the Personal Responsibility Work Opportunity Reconciliation Act (PRWORA) and its lead cash assistance program Temporary Assistance to Needy Families (TANF), states have taken unique and divergent approaches to welfare policy implementation. One popular approach to workfare delivery, known as privatization, involves contracting with non-profit and for-profit entities operating within the private sector. The General Accounting Office reports that nearly every state is privatizing TANF services to some degree through third-party contracts, but very little is understood about why variation in contracting exists and the ramifications for the program outcomes of welfare recipients. This dissertation …

Creed Vs. Deed: Secession, Legitimacy, And The Use Of Child Soldiers, Trace C. Lasley

Theses and Dissertations--Political Science

The use of child soldiers has troubled human rights activists, policy-makers, and local communities for decades. Although rebellions around the world routinely use children in their activities, many do not. Despite its overwhelming importance for conflict resolution, the topic of child soldiers remains understudied. My research blends classic rational choice and constructivist themes to develop an explanation for when child soldiers will be used, and when they will be avoided.

The likelihood of child recruitment is influenced by the value of international opinion; this is determined by the groups' long-term goals. Secessionist rebellions desire to have their own state. However, …

Global Kentucky (Winter 2012), University Of Kentucky International Center

Global Kentucky

No abstract provided.

Relationship Between Physical Fitness Measures And Occupational Physical Ability In University Law Enforcement Officers, Annie Q. Beck

Theses and Dissertations--Kinesiology and Health Promotion

Law enforcement on academic campuses can be a physically demanding profession. Law enforcement officers (LEOs) may be required to perform a variety of physical tasks. Identifying which physical fitness characteristics are associated with these tasks will guide the development of appropriate and effective exercise programs. Therefore the purpose of this study was to identify physical fitness and demographic characteristics associated with the occupational physical ability of university LEOs. Sixteen male LEOs (age: 33.1±8.7 yr.; body mass: 87.2±11.2 kg; height: 178.9±7.9 cm) performed an officer physical ability test (OPAT) that simulated a foot chase of a suspect. In addition, the officers …

Changes To The Equine Hindgut Microflora In Response To Antibiotic Challenge, Brittany E. Harlow

Theses and Dissertations--Animal and Food Sciences

Antibiotics are important to equine medicine, but can cause detrimental side-effects including reduced feed intake, allergic reactions, and diarrhea. Antibiotic-associated diarrhea (AAD) is attributed to disruption of the hindgut microflora, permitting proliferation of pathogenic microbes. The objectives were to evaluate the effects of antibiotics on beneficial fecal bacteria, AAD-associated pathogens, microbial species richness and fermentation. Horses were assigned to treatment groups: control (no antibiotics, n=6), trimethoprim-sulfadiazine (oral, n=6), or sodium ceftiofur (IM, n=6). Fecal samples were taken during adaptation (3 wk), antibiotic challenge (1 wk), and withdrawal (1 wk). Fecal cellulolytics decreased by >99% during challenge and did not recover …

Co-Grazing Beef Cattle And Goats In Kentucky, David C. Ditsch, Patty Scharko

Plant and Soil Sciences Research Report

A two season grazing study of mixed (goats and beef cattle) species was conducted in 2006 and 2008 at Sebastian Farms in Breathitt County KY. The objective of this study was to determine if the order of mixed species grazing affected beef cattle and goat weight gain and goat exposure to the barber pole worm (Haemonchus contortus) in a rotational grazing system. In this study, two co-grazing management strategies were tested. In treatment 1, goats and cattle were rotationally grazed together. In treatment 2, goats rotated through pastures as first grazers followed by cattle. Each co-grazing treatment was …

Organizational Adaptation Through Diffusion And Social Networks: A Study Of Family Consumer Sciences Extension Agents, Deborah Adkins Murray

Theses and Dissertations--Educational Leadership Studies

This study examines the interconnectedness of social networks of the early adopter Family and Consumer Science Extension Agents (FCS Agents) of the Mental Healthiness and Aging Initiative (MHAI) pilot conducted in eleven (11) eastern Kentucky counties between October 2007 and April 2009 and compares the social network connections of the FCS Agents in the other six Extension Districts in Kentucky.

This research used whole-network survey analysis applying the social network approach, a conceptual model for explaining the communication of new ideas and information within an organizational network. Organizational networks are important structural elements of organizational systems and key to understanding …

The Adverse Effects Of Aquatic Invasive Species On Native Commercial And Recreational Fisheries Of The Great Lakes And The Exacerbation Of The Problem By Judicial Reluctance To Act, Andrew S. Leung

Kentucky Journal of Equine, Agriculture, & Natural Resources Law

No abstract provided.

Harvesting A Lawsuit: Challenging The Enforcement And Validity Of Monsanto's Transgenic Seed Patents, Kelly E. Calder

Kentucky Journal of Equine, Agriculture, & Natural Resources Law

No abstract provided.