Digital Commons Network^™

Assessing Seismic Hazard In Western Kentucky And At The Paducah Gaseous Diffusion Plant: An Overview Of The Issues, Mitigation Strategies, And The Research Conducted By The Kentucky Geological Survey, Zhenming Wang, Seth Carpenter

Bulletin--KGS

The exposure of homes, infrastructure, and critical facilities in western Kentucky, including the Paducah Gaseous Diffusion Plant (PGDP), to potential strong seismic shaking from the New Madrid Seismic Zone (NMSZ) has been a major impetus for decades of effort to characterize seismic hazards by the Kentucky Geological Survey (KGS). The purpose of this report is to provide 1) a summary of the earthquake hazards that affect Kentucky and KGS’s ongoing earthquake research, including seismic monitoring, 2) background on the types of seismic hazards in general and how they are quantified in seismic hazard assessments, including strengths and weaknesses of the …

Multi-Jurisdictional Hazard Mitigation Plan For Landslides For The Big Sandy Area Development District, Kentucky, Matt M. Crawford, Hudson J. Koch, Jason M. Dortch

Contract Reports--KGS

Landslides are a complex geologic hazard that occurs worldwide, impacting lives, infrastructure, and property. The Big Sandy Area Development District, Kentucky incurs high landslide activity impacting several municipalities. This hazard mitigation planning project includes landslide susceptibility and risk assessments for the Big Sandy Area Development District. We based the landslide susceptibility model on statistics of hillslope morphological features such as slope, curvature, roughness, aspect, and elevation. Using a dual machine learning approach, we modeled the probability of landslide occurrence, defined as an area that is occupied, or might be occupied in the future, by a landslide. We also developed the …

Digital Footprints: Freedom On The Move At The University Of Kentucky, Vanessa Holden, Reinette F. Jones, Jennifer A. Bartlett, Kopana Terry

Library Presentations

During the late 18th through the mid-19th centuries, the Commonwealth of Kentucky saw significant movement of self-emancipated people seeking freedom from bondage. Often referred to as “runaways” or “fugitive slaves,” in historical texts, self-emancipated people defined freedom in many ways. These migrations were widely documented in newspaper advertisements known as fugitive slave advertisements and runaway ads in local newspapers published throughout the state. Access to these materials (often buried in databases or on microform) has been problematic at best. Enter the Self Emancipated and Enslaved People in Kentucky (SEEK) Project, a partnership between faculty in the University of Kentucky Libraries …

Design And Optimization Of High-Efficiency Coreless Pcb Stator Axial Flux Pm Machines With Minimal Eddy And Circulating Current Losses, Yaser Chulaee, Greg Heins, Ben Robinson, Ali Mohammadi, Mark Thiele, Dean Patterson, Dan M. Ionel

Electrical and Computer Engineering Graduate Research

This paper proposes a systematic multi-step design procedure for highly efficient printed circuit board (PCB) stator coreless axial flux permanent magnet (AFPM) machines with minimal eddy and circulating current losses. The process begins with initial sizing, providing specific coefficients based on experience with multiple design projects. It continues with the optimization of the machine envelope design using an evolutionary algorithm and computationally efficient 3D finite element analysis (FEA) models. The subsequent step focuses on the detailed design of a PCB stator, aiming to minimize eddy and circulating current losses. Several open circuit loss mitigation techniques are proposed based on analytical …

An Exploration Of Affective Influences Of Mediation And Instructional Delivery Styles In The U.S. Adult Media Literacy Learning Context, Joe Huber

Theses and Dissertations--Communication

This dissertation explores how varied delivery strategies may influence college student affective learning in a mediated setting. I employed a hybrid-grounded approach to the exploration of student-participant interviews wherein student-participants engaged with one of two online media literacy learning modules. The results of this study illustrate that students at varying points of their epistemological development (Perry, 1968) may face different affective hurdles depending on how media literacy curriculum is presented. We may anticipate that: (1) students who are less epistemologically developed (those featuring dualistic attitudes) may struggle to receive content, especially in the case where a teacher-centric delivery-style is employed; …

Examining The Effects Of Restorative Narratives On Prosocial Behavioral Intentions: A Sem Analysis, Mehroz Sajjad

Theses and Dissertations--Communication

Society grapples with an array of intricate and intertwined social challenges, often characterized as wicked problems due to their multifaceted, persistent nature. The refugee crisis and food insecurity stand as poignant examples of these complex issues, with millions affected worldwide. In response to these challenges, there is a pressing need for individuals to engage in prosocial behaviors, aiming to alleviate the impacts of these crises.Against this backdrop, this dissertation delved into the realm of narrative persuasion to examine the effectiveness of restorative narratives and framing strategies as potential drivers of greater behavioral intentions. To address the hypotheses and research question, …

Breaking The Silence: A Mixed Methods Study On Opioid Education, Overdose Risks, And Treatment Education Among College Students, Anita Silwal

Theses and Dissertations--Communication

The opioid crisis is a national public health emergency in the United States. Opioid education, naloxone training, and medication for opioid use disorder treatment (MOUD) are evidence-based practices to mitigate opioid overdose. The opioid crisis is affecting people of all ages, including college students. Research indicates the gap in research among college students on how they perceive this public health emergency and how it is affecting them; thus, this dissertation aims to address the gap by examining college students' knowledge, attitude, and behavioral intentions toward opioid education, naloxone training, and referral to MOUD to those struggling with opioid addiction. The …

A Case Study In Program Evaluation: A Prospective Program Evaluation Of Timely Reporting And Action Of An Infectious Disease Outbreak, Destiny Cozart

Theses and Dissertations--Public Health (M.P.H. & Dr.P.H.)

Methicillin-resistant Staphylococcus aureus also known as MRSA is an infection of a staph bacteria. High school athletes are at risk of contracting MRSA through skin to skin contact and/or MRSA contaminated equipment. This case study uses the CDC's six-step framework for program evaluation to measure the effectiveness of the online training modules designed to increase the knowledge of staff and stakeholders about MRSA and infectious disease outbreaks. The findings from this evaluation will advise the potential change(s) implemented in training modules, ultimately to enhance competency for decision makers and prevent MRSA and infectious disease outbreak amongst high school athletic programs.

Leveraging Technology For Safer Roads For Vulnerable Road Users In South Africa, Ntombifuthi Ngobeni, Busisiwe Marole, Koketso Bosilong, Hlulani Nkuna

Kentucky Transportation Center Presentations

This research aims to enhance road safety, particularly for Vulnerable Road Users (VRUs) such as pedestrians and cyclists, through the use of both cutting-edge technologies and consideration of conventional engineering methods and solutions. The study focuses on innovative solutions related to the road environment and their impact on VRU safety, piloted at selected sites in South Africa. The research investigates the use of technologies such as video cameras, video analysis software, artificial intelligence and machine learning to conduct route risk assessments. These assessments inform the selection and implementation of effective safety measures tailored to enhance VRU safety. By understanding the …

Considerations And Applications Of Environmental Dna In Biodiversity Studies, Sarah Tomke

Theses and Dissertations--Forestry and Natural Resources

Environmental DNA (eDNA) sampling—the detection of species through genetic material shed into the environment—has become an efficient and reliable method for biodiversity assessments. The method has grown in popularity due to its non-invasive and non-destructive nature, and has revolutionized monitoring efforts for rare, elusive, and cryptic species for which traditional sampling approaches are often costly and ineffective. Hundreds of studies have utilized this technique to study species occupancy, delineate distributions, and assess relative community composition. Although eDNA sampling is an effective strategy for many conservation and ecological studies, recently, light has been shed on some of its potential drawbacks and …

Africa’S Overlooked Top Predator: Towards A Better Understanding Of Martial Eagle Feeding Ecology In The Maasai Mara, Kenya, Richard Stratton Hatfield, Allison G. Davis, Ralph Buij, John J. Cox, Shiv Kapila, Lemein Parmuntoro, Simon Thomsett, Munir Z. Virani, Peter Njoroge, Frank Van Langevelde

Forestry and Natural Resources Faculty Publications

Raptors exert top-down influences on ecosystems via their effects on prey population dynamics and community composition. Most raptors are sympatric with other predators, thus complicating our understanding of their relative influence in these systems. Estimates of kill rates and prey biomass recycling have been used as predation metrics that allow quantitative comparison among species and assessment of the relative role of single species within complex food webs. Few studies have produced findings of kill rates or prey biomass recycling for raptors. We used a supervised machine learning algorithm to behaviourally classify high resolution accelerometer informed GPS locations of tagged adult …

Investigating The Use Of Serious Games For Cancer Control Among Children And Adolescents: Scoping Review, Sunghak Kim, Ebling Library, Olufunmilola Abraham

Pharmacy Practice and Science Faculty Publications

Background: Effective health care services that meet the diverse needs of children and adolescents with cancer are required to alleviate their physical, psychological, and social challenges and improve their quality of life. Previous studies showed that serious games help promote people’s health. However, the potential for serious games to be used for successful cancer control for children and adolescents has received less attention.

Objective: This scoping review aimed to map the use of serious games in cancer prevention and cancer care for children and adolescents, and provide future directions for serious games’ development and implementation within the context of cancer …

Navigating Success In Higher Education: Generative Ai, Financial Well-Being, And Parental Support, Tanya Gardner

Theses and Dissertations--Public Policy and Administration

Postsecondary education is viewed as a sure path to economic mobility. This dissertation contains three essays which examine correlates of postsecondary value. Postsecondary students face a variety of stressors throughout their college career which may impact their ability to be successful. They must complete their coursework and pass their classes while balancing work, social, and familial obligations. Tools such as generative AI may help students achieve their goals even in the face of personal challenges such as low financial stability or the inability to afford the high costs of college. Together these essays add to the body of literature which …

Essays On The Dynamics Of Subnational Public Finance In Indonesia, Much Rosidi

Theses and Dissertations--Public Policy and Administration

This dissertation comprises three essays that collectively explore the intricacies of subnational public finance in Indonesia: vehicle tax amnesty, property tax competition, and corruption. The research aims to understand the dynamics shaping fiscal policies at the subnational level.

In the first essay, I examine vehicle tax amnesty programs in Indonesia that have been very popular in dealing with high delinquency rates. From 2008 to 2020, provincial amnesties occurred every 2.5 years on average. Using the variation in the timing of the province’s amnesty adoptions, I estimate the effect of vehicle tax amnesty on vehicle tax revenue using difference-in-differences. The short-run …

How Black Undergraduate Students Experience Whiteness In Postsecondary Education, Karen Margaret Guettler-James

Theses and Dissertations--Educational, School, and Counseling Psychology

Critical whiteness scholars have described whiteness as a system of oppression that privileges White identities above others and perpetuates White supremacy. On the college campus, institutional, social, and historical norms reinforce the educational status quo and work together to maintain a system of whiteness that marginalizes Black students. This study investigated perceptions of whiteness held by student participants who self-identify as Black undergraduate students. Through focus group interviews, participants were asked to share their lived experiences with whiteness on the college campus. With the words of the participants, I reveal how campus standards that align with White Eurocentric norms devalue …

Project Final Report Watershed Center Of Excellence, Kentucky Water Resources Research Institute

KWRRI Research Reports

With the goal of providing a structured foundational background for watershed management to Kentucky’s watershed coordinators and other water quality professionals, the Kentucky Water Resources Research Institute developed the Kentucky Watershed Academy, a six-module series of core training content. The modules address the following subject areas:

• Module 1: The Clean Water Act & Related Water Quality Laws

• Module 2: Water Quality Basics

• Module 3: Dealing with Data

• Module 4: Land Use Impacts & Related Best Management Practices

• Module 5: Likely Partners

• Module 6: Effective Communications

As a result of this project, a total of …

Maximizing Mining Operations: Unlocking The Crucial Role Of Intelligent Fleet Management Systems In Surface Mining’S Value Chain, Arman Hazrathosseini, Ali Moradi Afrapoli

Earth and Environmental Sciences Faculty Publications

On the one side, the operational expenses of mining enterprises are showing an upward trend; and on the other side, conventional mining fleet management systems (FMSs) are falling short in addressing the high-dimensionality, stochasticity, and autonomy needed in increasingly complex operations. These major drivers for change have convinced researchers to search for alternatives including artificial-intelligence-enabled algorithms recommended by Mining 4.0. The present study endeavors to scrutinize this transition from a business management point of view. In other words, a literature review is carried out to gain insight into the evolutionary trajectory of mining FMSs and the need for intelligent algorithms. …

Elucidation Of Mismatch Repair Regulation By Abl1: Advantages/Disadvantages Of Tyrosine Kinase Inhibitor Treatment, Hannah Daniels

Theses and Dissertations--Toxicology and Cancer Biology

DNA mismatch repair (MMR) is a critical repair process necessary for not only repairing mispairs incorporated into the DNA during replication, but also for inducing apoptosis in response to certain types of DNA damage. MMR is required for maintaining genomic integrity and due to the importance of this pathway, any impairment of its function can lead to increased mutation frequency, which is well known to be a driving force of cancer development, progression, and resistance. Despite extensive studies involving the proteins involved in the MMR pathway, the regulation of those proteins remains relatively unknown. Regulation of MLH1, a protein necessary …

Acquired Treatment Resistance In Prostate Cancer Via The Production Of Radiation Derived Extracellular Vesicles Containing Mitochondrial Proteins, Caitlin Miller

Theses and Dissertations--Toxicology and Cancer Biology

Radiation treatment (RT) is one of the most commonly administered treatments for prostate cancer (PCa) patients, yet the recurrence of tumors after RT remains one of the significant challenges in the eradication of PCa. In addition to induction of DNA damage, ROS production, and cell death, we found that RT promotes Extracellular vesicle (EV) production in PCa cells, at least in part, through H₂O₂ production (Miller CE et al., Antioxidants 2022, PMID 36358489). Since we observed EV production upon RT, EVs and their contents could play a role(s) in cancer survival after RT. By using flow cytometry …

Understanding The Mechanism Of Ferroptosis Susceptibility Variation In Colorectal Cancer, Aziza Alshahrani

Theses and Dissertations--Toxicology and Cancer Biology

Colorectal cancer (CRC) is the second leading cause of cancer-related death worldwide. Despite the use of chemotherapeutic agents, CRCs remains to be difficult to cure at least partially due to their intrinsic and/or acquired resistance to cell death inducers. Ferroptosis is a form of regulated cell death that caused by the accumulation of lipid peroxides. Studies have shown that dysregulation of ferroptotic pathways is associated with the development of resistance to various cancer treatment. Glutathione peroxidase 4 (GPX4) is a known target for inducing ferroptosis due to its critical role in detoxifying lipid hydroperoxides, and ferroptosis suppressor protein (FSP1) also …

Porcupine’S Role In The Enhancement Of Enzalutamide Efficacy In Drug Resistant Prostate Cancer, Katelyn Jones

Theses and Dissertations--Toxicology and Cancer Biology

Androgen receptor (AR) signaling continues to participate as a vital component of castration-resistant prostate cancer (CRPC). Subsequently, this has led to the development of Androgen Signaling Inhibitors (ASI), specifically Enzalutamide (ENZ), which is a direct inhibitor of AR, to clinically manage CRPC. Inevitably, ENZ treatment only provides improvement for approximately two months before advancing to an incurable form, ENZ-resistant CRPC. With PCa ranking as the second leading cause of cancer-related deaths in USA males, there is an urgency and necessity for the discovery and development of novel therapeutic approaches for CRPC. Wnt signaling has been extensively documented in its involvement …

Therapeutic Approaches And Novel Mechansims In Cancer Progression, Kendall Simpson

Theses and Dissertations--Toxicology and Cancer Biology

Prostate cancer (PCa) remains the most diagnosed cancer among men in the United States. There are various therapeutic routes that are implored to combat this fatal disease, and our work aims to increase the options made available to PCa patients. A combination treatment of Enzalutamide (Enz), an FDA approved drug for castration-resistant PCa patients, and Metformin, an FDA approved drug for type 2 diabetes, was utilized to enhance the efficacy of Enz in Enz-resistant PCa, both in vitro and in vivo. Thymic Lymphoma is one of the most common malignancies that can occur in various tissues and organs. Genomic stability …

Delineating Contributions Of Genotype And Lineage To Lung Cancer Therapy Response, Kassandra Jo Naughton

Theses and Dissertations--Toxicology and Cancer Biology

Non-small cell lung cancer (NSCLC) heterogeneity is a major challenge for determining effective treatment strategies. Adenocarcinomas (ADCs) and squamous cell carcinomas (SCCs) are histologically and epigenetically distinct subtypes of NSCLC. Patients with ADC tumors harboring mutations in both KRAS and LKB1 (aka STK11) have lower survival rates than those with KRAS-only tumors. KRAS/LKB1 tumors are not only aggressive, but also respond poorly to immunotherapy. However, these data are limited to ADCs, and it is unclear if SCCs with this genotype are also resistant to immunotherapy. We developed a mouse model of Kras^mut/Lkb1^mut capable of producing …

Generating Climate Resilience Or Intensifying Vulnerabilities? A Feminist Poltitical Ecology Analysis Of Climate Resilient Agriculutre Projects In Sri Lanka’S Dry Zone, Nethmi Sachithma Perera Bathige

Theses and Dissertations--Geography

Conserving water for irrigation of crops has become a concern in the dry zone of Sri Lanka due to changes in climate patterns. In response, the United Nations Development Program (UNDP) has developed climate-resilient water management projects designed to build climate-resilience and water management practices among farmers. One such program called ‘Wew Gam Pubuduwa’ disseminates climate smart home gardening techniques, where women farmers receive sprinkler and drip irrigation systems, seeds and fertilizers, as well as training on water management methods. This study draws on a feminist political ecology framework to analyze the experiences of women home gardeners who …

Digital (Re)Production: Spatial Mediations Through Augmented Reality Landscapes In ‘Pokemon Go’, Brigitte Pulminar Perkins

Theses and Dissertations--Geography

Since 2016, the mobile augmented reality game Pokémon GO has renewed interest within communities by mediating spatial engagement using in-game markers that must be engaged with throughout physical urban landscapes. This thesis identifies factors that influence the spatial distribution of digital markers used by this game to help inform analyses of urban gamification, urban spatial distribution, and cultural knowledge production processes. Drawing specifically on theories of urban spatialization and digital media studies, I highlight features of physical and digital legacies of redlining within Lexington, KY that are reproduced via Pokémon GO. I argue that the urban racialized landscape of Lexington …

State Governance And Less-Skilled Migrant Workers In South Korea, Weejun Park

Theses and Dissertations--Geography

This dissertation examines the migration governance of South Korea with a focus on the immigration of less-skilled migrant workers. While geographers and broader social scientists have explored this topic, previous studies have two main foci: 1) individual immigrants and their activities; and 2) migration policy development. Despite these studies’ contribution to the scholarship, there seems to be a relative lack of interest in the South Korean state as a potentially crucial actor in governing less-skilled migrant workers. To address this gap, this dissertation draws upon (political) geography, related social sciences, and interdisciplinary fields such as border studies, migration studies, and …

A Case Study In Prospective Program Evaluation, Sarai Rosemary Combs

Theses and Dissertations--Public Health (M.P.H. & Dr.P.H.)

Evaluation is a helpful tool in public health to provide transparency about community interventions and programs. The following is a prospective evaluation of a case study, looking at a recently designed program by the Lexington-Fayette County Health Department, as a capstone project for the Health Management and Policy concentration of the Masters in Public Health program of the College of Public Health. The health department developed a series of online training modules to increase knowledge of Methicillin-resistant staphylococcus aureus (MRSA) and other similar organism outbreaks and how to respond to these outbreaks. The program targets were Fayette County Public School …

A Case Study In Program Evaluation, Iantha Wright

Theses and Dissertations--Public Health (M.P.H. & Dr.P.H.)

The framework for program evaluation is a systematic way of improving and accounting for public health actions by providing practical, feasible, ethical, and accurate information. As a practical, non-prescriptive tool, it guides public health professionals through the essential steps in program evaluation. The framework uses the six steps to understand how to improve and conduct assessments effectively. Additionally, it emphasizes integrating stakeholders and using ongoing evaluation strategies to plan effective interventions, improve existing programs, and demonstrate the efficient use of resources.

The Health Literacy Practices Of Rehabilitation Providers Of Perioperative Orthopedic Education, Allen Keener

Theses and Dissertations--Rehabilitation Sciences

Health literacy is the ability to utilize information to make decisions about one’s health or the health of others. It is estimated that a large percentage of the population has inadequate health literacy, yet healthcare professionals, including rehabilitation providers often do not have procedures in place for assessing and addressing the health literacy of their patients. Related to orthopedic patients, a large portion of the interventions are educational in nature. Therefore, it is important that the health literacy of orthopedic patients be considered when addressing their needs perioperatively. There is little currently published related to health literacy among rehabilitation providers …

Gas Assisted Electron Beam Patterning Processes, Deepak Kumar

Theses and Dissertations--Electrical and Computer Engineering

Radiolysis is a complex phenomenon in which molecules subjected to ionizing radiation form new chemical species. Electron-beam irradiation has proven to be a versatile approach for significantly altering materials’ properties and forms the basis for electron-beam lithography using both organic and inorganic resists. Electron-beam exposure is normally carried out under high vacuum conditions to reduce contamination and allow for unhindered interaction between the electrons and the resist material. Exposure under an ambient gas at sub-atmospheric pressures has been found to provide a distinct mechanism which can be exploited to circumvent some of the challenges associated with material processing and significantly …