Digital Commons Network^™

Novel Model For Multispecies Biofilms That Uses Rigid Gas-Permeable Lenses, Rebecca Peyyala, Sreenatha S. Kirakodu, Jeffrey L. Ebersole, Karen F. Novak

Center for Oral Health Research Faculty Publications

Oral biofilms comprise complex multispecies consortia aided by specific inter- and intraspecies interactions occurring among commensals and pathogenic bacterial species. Oral biofilms are primary initiating factors of periodontal disease, although complex multifactorial biological influences, including host cell responses, contribute to the individual outcome of the disease. To provide a system to study initial stages of interaction between oral biofilms and the host cells that contribute to the disease process, we developed a novel in vitro model system to grow biofilms on rigid gas-permeable contact lenses (RGPLs), which enable oxygen to permeate through the lens material. Bacterial species belonging to early- …

Charting Strange Lands: The Acquisitions Of E-Books, Kate Seago

Library Presentations

No abstract provided.

7 Things You Should Know About The Modern Learning Commons, Joan Lippincott, Stacey Greenwell

Library Faculty and Staff Publications

The learning commons, sometimes called an "information commons," has evolved from a combination library and computer lab into a full-service learning, research, and project space. As a place where students can meet, talk, study, and use "borrowed" equipment, the learning commons brings together the functions of libraries, labs, lounges, and seminar areas in a single community gathering place. The cost of a learning commons can be an obstacle, but for institutions that invest in a sophisticated learning commons, the new and expanded partnerships across disciplines facilitate and promote greater levels of collaboration. The commons invites students to devise their own …

What's Love Got To Do With It?: Family, Sex, And Domestic Violence In Contemporary Irish Women's Fiction, Mary Ryan

disClosure: A Journal of Social Theory

No abstract provided.

Cataloging Electronic Resources: E-Books, Kathryn Lybarger

Library Presentations

No abstract provided.

On Borders And Biopolitics: An Interview With Eithne Luibhéid, Samantha Herr, Tim Vatovec

disClosure: A Journal of Social Theory

No abstract provided.

Marriage, Power, And The Law In Jaime Humberto Hermosillo's Esmeralda Comes By Night, Osvaldo Di Paolo

disClosure: A Journal of Social Theory

No abstract provided.

Sugarmama, Shannon Sigler

disClosure: A Journal of Social Theory

No abstract provided.

Falling Through The Cracks: Queer Theory, Same-Sex Marriage, Lawrence V Texas, And Liminal Bodies, Andrew Clark

disClosure: A Journal of Social Theory

No abstract provided.

Errata For Disclosure 19 (2010): Consuming Culture

disClosure: A Journal of Social Theory

No abstract provided.

Rda: Resource Description And Access, Kathryn Lybarger

Library Presentations

No abstract provided.

Characteristics Of Kentucky’S Nursery And Greenhouse Industries, Dewayne L. Ingram, Winston Dunwell, Alan Hodges

Agriculture and Natural Resources Publications

The nursery and greenhouse industry, distributed throughout Kentucky, is diverse and contributes significantly to the local and state economy. This industry represents the largest segment of Kentucky’s sales of horticultural products and is comprised almost completely of farm families. Nursery and greenhouse crops are produced and marketed in containers or grown in the field and dug and sold as balled and burlapped or bare root plants. Most of Kentucky’s nursery and greenhouse crops are marketed in Kentucky and surrounding states.

Southeastern Law Librarian Spring 2011, Seaall

Newsletters

No abstract provided.

Session 2c, Kentucky Water Resources Research Institute, University Of Kentucky

Kentucky Water Resources Annual Symposium

• Comparing the Kentucky Phosphorus Index with the P Loss Calculated with a Process-Based Model, Carl Bolster, USDA-ARS, AWMRU, Bowling Green, KY
• Kentucky Nutrient Criteria Development and Reduction Strategy, Clark Dorman, Water Quality Branch, KY DOW
• Genotypic Diversity of Escherichia coli Isolates from Environmental Sources and the Influence on Transport Behavior, Kimberly Cook and others, USDA-ARS, AWMRU, Bowling Green, KY
• A Multiparameter Approach for the Identification of Leaking and Overflowing Sanitary Sewers in the Wolf Run Watershed, Tricia Coakley and Gail Brion, Depts of Earth and Environmental Sciences and Civil Engineering, UK

Session 2b, Kentucky Water Resources Research Institute, University Of Kentucky

Kentucky Water Resources Annual Symposium

• Building Support for Protecting and Restoring Plain, Frumpy, Dowdy Streams, Barry Tonning, Tetra Tech, Mt. Sterling, KY
• Monitoring Water Quality in Hinkston Creek: Providing Information for Action, Brian Reeder and April Haight, Center for Environmental Education, Morehead State University
• The Story of the Hinkston Creek Watershed Data, Gregory Sousa and others, Tetra Tech
• Implementation of Watershed Based Plans in the Dix River Watershed, Caroline Walz and Malissa McAlister, OSM/VISTA Dix River Watershed Coordinator and KWRRI

Session 1c, Kentucky Water Resources Research Institute, University Of Kentucky

Kentucky Water Resources Annual Symposium

• Bush Honeysuckle Induced Aquatic Hypoxia, Stephanie Hayes and Richard Durtsche, Dept of Biological Sciences, NKU
• A Laboratory Scale, Continuous Flow Bioreactor for the Removal of Manganese in Water Supplies, Michael Snyder and Y.T. Wang, Dept of Civil Engineering, UK
• Flood Impact Due to Dam Failure: An Assessment of Current Studies and the Appropriateness of the Methodologies Applied to the Dix Dam, Allen Cantrell and Scott Yost, Dept of Civil Engineering, UK
• Development of a Comprehensive Sediment Transport Method in First Order Watersheds with Contour Coal Mining, Darren Martin and Jimmy Fox, Dept of Civil Engineering, UK

Engineered Nanomaterials: Exposures, Hazards, And Risk Prevention, Robert A. Yokel, Robert C. Macphail

Pharmaceutical Sciences Faculty Publications

Nanotechnology presents the possibility of revolutionizing many aspects of our lives. People in many settings (academic, small and large industrial, and the general public in industrialized nations) are either developing or using engineered nanomaterials (ENMs) or ENM-containing products. However, our understanding of the occupational, health and safety aspects of ENMs is still in its formative stage. A survey of the literature indicates the available information is incomplete, many of the early findings have not been independently verified, and some may have been over-interpreted. This review describes ENMs briefly, their application, the ENM workforce, the major routes of human exposure, some …

Memorias De Un Terminal Periférica, Alejandro Reyes Arias

Nomenclatura: aproximaciones a los estudios hispánicos

No abstract provided.

Reassessing History, Rediscovering Memory: Jorge Semprún’S Veinte Años Y Un Día, Daniela Omlor

Nomenclatura: aproximaciones a los estudios hispánicos

No abstract provided.

Systematic Two-Hybrid And Comparative Proteomic Analyses Reveal Novel Yeast Pre-Mrna Splicing Factors Connected To Prp19, Liping Ren, Janel R. Mclean, Tony R. Hazbun, Stanley Fields, Craig Vander Kooi, Melanie D. Ohi, Kathleen L. Gould

Molecular and Cellular Biochemistry Faculty Publications

Prp19 is the founding member of the NineTeen Complex, or NTC, which is a spliceosomal subcomplex essential for spliceosome activation. To define Prp19 connectivity and dynamic protein interactions within the spliceosome, we systematically queried the Saccharomyces cerevisiae proteome for Prp19 WD40 domain interaction partners by two-hybrid analysis. We report that in addition to S. cerevisiae Cwc2, the splicing factor Prp17 binds directly to the Prp19 WD40 domain in a 1:1 ratio. Prp17 binds simultaneously with Cwc2 indicating that it is part of the core NTC complex. We also find that the previously uncharacterized protein Urn1 (Dre4 in Schizosaccharomyces pombe) directly …

A Brief History Of Phssr: The National Coordinating Center. Lessons From History, F. Douglas Scutchfield Md

Preventive Medicine and Environmental Health Presentations

No abstract provided.

Security Monitoring System For A Bulk Foodstuff Transport Container, Christopher Dwight Thompson, Suraj M. Alexander, William L. Christ, Brian D. Luck, James Ryan Moore, Jonathan C. Paschal, Frederick Payne, Timothy S. Stombaugh, Nasrin Tabayehnejad, Phillip C. Womble

Biosystems and Agricultural Engineering Faculty Patents

A security monitoring system provides for the secure transport of a bulk foodstuff container. The system includes an electromechanical locking mechanism allowing access by only authorized persons, a positional locator for determining the geographical position of the bulk foodstuff transport container, and a controller associated with the transport container. The controller controls operation of the electromechanical locking mechanism, stores data received from the electromechanical locking mechanism and the positional locator, and communicates with a remote data processor in near real time. A handheld user interface device is configured to control operation of the controller, to process and store data received …

On Reducing Communication Energy Using Cross-Sensor Coding Technique, Kien Nguyen, Thinh Nguyen, Sen-Ching Cheung

Electrical and Computer Engineering Faculty Publications

This paper addresses the uneven communication energy problem in data gathering sensor networks where the nodes closer to the sink tend to consume more energy than those of the farther nodes. Consequently, the lifetime of a network is significantly shortened. We propose a cross-sensor coding technique using On-Off keying which exploits (a) the tradeoff between delay and energy consumption and (b) the network topology in order to alleviate the problem of unequal energy consumption. We formulate our coding problem as an integer linear programming problem and show how to construct a number of codes based on different criteria. We show …

Evaluation Of Immune Responses Following Infection Of Ponies With An Ehv-1 Orf1/2 Deletion Mutant, Gisela Soboll Hussey, Stephen B. Hussey, Bettina Wagner, David W. Horohov, Gerlinde R. Van De Walle, Nikolaus Osterrieder, Lutz S. Goehring, Sangeeta Rao, David P. Lunn

Veterinary Science Faculty Publications

Equine herpesvirus-1 (EHV-1) infection remains a significant problem despite the widespread use of vaccines. The inability to generate a protective immune response to EHV-1 vaccination or infection is thought to be due to immunomodulatory properties of the virus, and the ORF1 and ORF2 gene products have been hypothesized as potential candidates with immunoregulatory properties. A pony infection study was performed to define immune responses to EHV-1, and to determine if an EHV-1 ORF1/2 deletion mutant (ΔORF1/2) would have different disease and immunoregulatory effects compared to wild type EHV-1 (WT). Infection with either virus led to cytokine responses that coincided with …

Activation Of Β-Catenin And Akt Pathways By Twist Are Critical For The Maintenance Of Emt Associated Cancer Stem Cell-Like Characters, Junlin Li, Binhua P. Zhou

Molecular and Cellular Biochemistry Faculty Publications

BACKGROUND: Epithelial-mesenchymal transition (EMT) not only confers tumor cells with a distinct advantage for metastatic dissemination, but also it provides those cells with cancer stem cell-like characters for proliferation and drug resistance. However, the molecular mechanism for maintenance of these stem cell-like traits remains unclear.

METHODS: In this study, we induced EMT in breast cancer MCF7 and cervical cancer Hela cells with expression of Twist, a key transcriptional factor of EMT. The morphological changes associated with EMT were analyzed by immunofluorescent staining and Western blotting. The stem cell-like traits associated with EMT were determined by tumorsphere-formation and expression of ALDH1 …

The Differential Effect Of Toxoplasma Gondii Infection On The Stability Of Bcl2-Family Members Involves Multiple Activities, John Cherrington Carmen, Anthony Peter Sinai

Microbiology, Immunology, and Molecular Genetics Faculty Publications

The regulation of mitochondrial permeability, a key event in the initiation of apoptosis is governed by the opposing actions of the pro- and anti-apoptotic members of the BCL2-family of proteins. The BCL2-family can be classified further based on the number of BCL-homology (BH) domains they encode. Pathogen mediated modulation of BCL2-family members play a significant role in their ability to affect the apoptotic pathways in the infected host cell. The protozoan parasite Toxoplasma gondii establishes a profound blockade of apoptosis noted by a requirement for host NFκB activity and correlating with the selective degradation of pro-apoptotic BCL2-family members. In this …

Specific Thiazolidinediones Inhibit Ovarian Cancer Cell Line Proliferation And Cause Cell Cycle Arrest In A Pparγ Independent Manner, Linah Al-Alem, R. Chase Southard, Michael W. Kilgore, Thomas E. Curry

Pharmacology and Nutritional Sciences Faculty Publications

BACKGROUND: Peroxisome Proliferator Activated Receptor gamma (PPARγ) agonists, such as the thiazolinediones (TZDs), have been studied for their potential use as cancer therapeutic agents. We investigated the effect of four TZDs--Rosiglitazone (Rosi), Ciglitazone (CGZ), Troglitazone (TGZ), and Pioglitazone (Pio)--on ovarian cancer cell proliferation, PPARγ expression and PPAR luciferase reporter activity. We explored whether TZDs act in a PPARγ dependent or independent manner by utilizing molecular approaches to inhibit or overexpress PPARγ activity.

PRINCIPAL FINDINGS: Treatment with CGZ or TGZ for 24 hours decreased proliferation in three ovarian cancer cell lines, Ovcar3, CaOv3, and Skov3, whereas Rosi and Pio had no …

Transfected Mosquito Vectors, Stephen L. Dobson

Entomology Faculty Patents

A method is provided for producing an artificial infection in a Culicidae (mosquito) species. The mosquitoes include species within the subfamilies Culicinae and Anophelinae, and the species include Aedes albopictus, Aedes aegypti and Aedes polynesiensis infected with a Wolbachia infection. The infection may be a strain of Wolbachia which does not normally or naturally infect the selected mosquito species. The artificially infected Aedes mosquito can be introduced into a mosquito population to control the reproduction capability of the population by introducing an incompatible Wolbachia infection. The present method can be used as a novel means to limit mosquito-borne pathogens and …

Teens Texting And Consequences: A Brief Review, Archana Srinivas, Megan White, Hatim A. Omar

Pediatrics Faculty Publications

The aim of this paper is to summarize the current literature on texting use amongst adolescents. A brief overview will be presented on the prevalence of texting among teenagers, the use of texting for sexting and cyberbullying as well as the dangers of texting while driving. This paper will serve as a brief overview of these topics in order to bring to light the emerging challenges that texting presents to the mental and physical well-being of adolescents in an effort to evoke further discussion regarding the need for increasing awareness and education to parents, educators, law makers and health care …

Comparative Analysis Of Rural And Urban Start-Up Entrepreneurs, Hyunjeong Joo

Theses and Dissertations--Agricultural Economics

This study investigates the reasons for apparent differences in entrepreneurship rates in rural and urban areas using a Survey of Rural Kentucky Residents (SRKR) and the Panel Study of Entrepreneurial Dynamics (PSED) data. We estimate the determinants of dissimilar characteristics for rural and urban areas in two aspects: one is individual and contextual resources; the other is cultural tendencies of resources.

The results of the analysis suggest that the difference in available individual, economic, and social support resources does not explain the observed difference in entrepreneurship rate. The results also indicate that gender, ethnicity, income, and number of children in …