Digital Commons Network^™

Explore The Relationship Among Lung Cancer Stigma, Social Support, And Psychosocial Distress, Lisa Maggio

Theses and Dissertations--Nursing

There is longstanding causal relationship between cigarette smoking and lung cancer. Smoke-free policies and anti-smoking campaigns have been linked to the decline in smoking acceptance and contribute to the unintended consequence of stigmatizing smokers. Lung cancer is viewed as a self-inflicted disease and patients’ feel judged in a manner different from other cancers affecting social interactions between family, friends, and healthcare professionals. Lung cancer stigma contributes to depression, anxiety, poor self-esteem, guilt, shame, blame, threatens a person’s social identity, and limits social support that deeply affects patients and their support persons.

This dissertation contains a review of the literature related …

A Comparative Life Cycle Assessment Of Denim Jeans And A Cotton T-Shirt: The Production Of Fast Fashion Essential Items From Cradle To Gate, Tara Hackett

Theses and Dissertations--Retailing and Tourism Management

As a result of harmful textile production, sustainability has become the movement by which the apparel industry explores solutions to improve procedures in fashion design to maintain a healthy environment. However, the issue is consumers trust the sustainability claims and marketing materials of apparel products at face value without knowing its environmental impact. The overall purpose of this research was to compare the environmental implications of widely produced and owned apparel products through a life cycle assessment approach. This life cycle assessment study examines key environmental impact categories of the materials and production phase (cradle to gate) of a pair …

Characterization Of Colletotrichum Species Causing Bitter Rot Of Apples In Kentucky Orchards, Misbakhul Munir

Theses and Dissertations--Plant Pathology

Multiple species of Colletotrichum can cause bitter rot disease of apple, but the identities and relative representation of the species causing the disease in Kentucky are unknown. A total of 475 Colletotrichum isolates were collected from diseased apples in 25 counties and characterized both morphologically and by using various molecular approaches. Four morphotypes corresponded to reported descriptions of bitter rot species. Morphotype 1, distinguished by the production of a pink color on potato dextrose agar (PDA), orange conidial masses, and fusiform spores, was consistent with C. acutatum. Morphotype 2, which produced gray or white mycelial colonies with orange conidial masses …

Glucocorticoid-Induced Chondrocyte Cytotoxicity At Doses Recommended For Intra-Articular Therapy In Horses, Wenying Zhu

Theses and Dissertations--Veterinary Science

Intra-articular glucocorticoid injections are commonly used to treat synovitis and osteoarthritis in horses. These agents are highly effective at relieving pain, swelling, and other symptoms of joint inflammation. The drugs also have therapeutic benefits by down regulating the expression of cytokines and protease enzymes that participate in the degradation of articular cartilage. However, detrimental effects on chondrocyte function and cell viability that is independent of osteoarthritis pathogenesis have been described and linked to glucocorticoid use. These side effects are both drug- and dose-dependent. This study tested the hypothesis that manufacture recommended dosage levels of methylprednisolone, betamethasone, and triamcinolone that are …

Uterine Artery Rupture, An Angiopathy Of The Reproductive System Of The Mare: Occurrence And Potential Effects, Ana G. Toro Mayorga

Theses and Dissertations--Veterinary Science

The intent of this research was to identify if the degenerative changes within arteries in the endometrium (endometrial angiopathies) correlate with degenerative changes in the uterine arteries and can be used as a predictor of increased risk for uterine artery rupture (UAR). With this objective specimens from 20 mares that died from uterine artery rupture and 21 control mares that died from unrelated causes were obtained from cases submitted to the University of Kentucky Veterinary Diagnostic Laboratory (UKVDL) over a two-year period. Postmortem specimens of each mare were collected from the left and right uterine arteries at the origin, bifurcation, …

Parent Development And Wellbeing During The Launching Stage Of Parenthood, Deborah F. Keys

Theses and Dissertations--Family Sciences

At the present time, the young adult transition into adulthood has been extended, which has also extended the launching stage. One result of the extended launching stage is that parents are now involved in active parenting longer than before. The purpose of this study is to investigate the impact of the extended launching stage in key areas (the parent- child relationship and parent support) on parental emotional wellbeing. The contribution of this research is that it adds to the limited body of knowledge about normative launching stage parenting practices and outcomes. This dissertation is a three chapter manuscript that uses …

Sex, Dementia, And Long-Term Care: Public Perspectives, Erin L. Yelland

Theses and Dissertations--Family Sciences

The current mixed methods study utilized an ecological framework to examine public perspectives toward sexual behaviors among long-term care residents with dementia. Analyzing attitudes of the public is an integral component of understanding the entire ecological system that affects the development and overall well-being of a long-term care resident. Attitudes were examined using a multiple segment factorial vignette with a probability sample of 329 respondents from a southern state. Results indicate that attitudes were not statistically affected by sex or the elapsed time since diagnosis, and age, spousal disposition, and degree of intimacy predicted attitudes. A respondent’s education level also …

Mental Health Among Suicide Attempt Survivors: The Roles Of Stigma, Self-Disclosure, And Family Reactions, Laura M. Frey

Theses and Dissertations--Family Sciences

Although research has shown that mental-health stigma can impact an individual’s well-being, little is known about who perpetrates suicide stigma. Moreover, anticipation of stigma could impact whether individuals disclose their suicidal experiences; yet, little is known about suicide disclosure and how family members’ reactions play a role in subsequent mental health. To address these gaps, three studies were designed to examine how stigma, suicide disclosure, and family reaction impact subsequent mental health of attempt survivors and those who have experience suicidal ideation.

Individuals who had previously experienced suicidal ideation or a previous suicide attempt (n = 156) were recruited …

The Impact Of Video Chatting On Idealization And Disillusionment For Long Distance Dating Couples, Laura Kusisto

Theses and Dissertations--Family Sciences

Previous research indicates a high rate of long distance relationships, especially among young adults. Yet, research in this area is lacking, particularly regarding the role of video chatting. Through the lens of the media richness theory and the hyperpersonal model, this qualitative study explores how video chatting impacts idealization and disillusionment in young adults’ long distance dating relationships. Data was collected through semi-structured interviews with both partners of six heterosexual couples. Data was analyzed using the constant comparative approach and following the basic framework of open, axial, and selective coding used in grounded theory research. Results indicate that video chatting …

Impact Of The Healthy Hunger-Free Kids Act On Changes In The Phytochemical Content Of School Lunch Menus And Implications Of Science-Based Nutrition Education On Promoting Student Identification Of Foods High In Phytochemicals, Siddhi Lalit Shroff

Theses and Dissertations--Nutrition and Food Systems

Concern that youth do not have enough fruit and vegetable intake lead to two strategies implemented to influence intake in the school environment: the Healthy Hunger-Free Kids Act (HHFKA) and Fighting with Food: Battling Chemical Toxicity with Good Nutrition program (FF), which could influence phytochemical content and knowledge regarding phytochemicals, respectively. Individual food logs (n=468) were assessed upon completion of FF curriculum to determine whether students were able to correctly apply their nutrition knowledge regarding FF. Menus from one district were analyzed pre-HHFKA and post-HHFKA in elementary (n=156), middle (n=171), and high schools (n=171), for change in the frequency of …

The Synergistic Impact Of Income And Rurality On Timely Mammograms In A National Sample Of Women In The United States, Asri Mumpuni

Theses and Dissertations--Public Health (M.P.H. & Dr.P.H.)

Introduction. Breast cancer is the cancer of highest incidence among women in the U.S., making it a significant public health problem. Currently, the U.S. Preventive Services recommends biennial screening mammography for women ages 50-74. This study examined the associations between socioeconomic status and rurality on breast cancer screening behavior. Methods. Data for this study come from the Centers for Disease Control and Prevention (CDC) Behavioral Risk Factor Surveillance System Survey (BRFSS). Breast cancer screening behavior was dichotomized into those who did not meet screening mammogram recommendations (2 years or more) and those who met screening mammogram recommendations (within the …

Novel Computational Methods For Transcript Reconstruction And Quantification Using Rna-Seq Data, Yan Huang

Theses and Dissertations--Computer Science

The advent of RNA-seq technologies provides an unprecedented opportunity to precisely profile the mRNA transcriptome of a specific cell population. It helps reveal the characteristics of the cell under the particular condition such as a disease. It is now possible to discover mRNA transcripts not cataloged in existing database, in addition to assessing the identities and quantities of the known transcripts in a given sample or cell. However, the sequence reads obtained from an RNA-seq experiment is only a short fragment of the original transcript. How to recapitulate the mRNA transcriptome from short RNA-seq reads remains a challenging problem. We …

High Quality Human 3d Body Modeling, Tracking And Application, Qing Zhang

Theses and Dissertations--Computer Science

Geometric reconstruction of dynamic objects is a fundamental task of computer vision and graphics, and modeling human body of high fidelity is considered to be a core of this problem. Traditional human shape and motion capture techniques require an array of surrounding cameras or subjects wear reflective markers, resulting in a limitation of working space and portability. In this dissertation, a complete process is designed from geometric modeling detailed 3D human full body and capturing shape dynamics over time using a flexible setup to guiding clothes/person re-targeting with such data-driven models. As the mechanical movement of human body can be …

Inducible Depletion Of Satellite Cells In Adult, Sedentary Mice Impairs Muscle Regenerative Capacity Without Affecting Sarcopenia, Christopher S. Fry, Jonah D. Lee, Jyothi Mula, Tyler J. Kirby, Janna R. Jackson, Fujun Liu, Lin Yang, Christopher L. Mendias, Esther E. Dupont-Versteegden, John J. Mccarthy, Charlotte A. Peterson

Physical Therapy Faculty Publications

A key determinant of geriatric frailty is sarcopenia, the age-associated loss of skeletal muscle mass and strength. Although the etiology of sarcopenia is unknown, the correlation during aging between the loss of activity of satellite cells, which are endogenous muscle stem cells, and impaired muscle regenerative capacity has led to the hypothesis that the loss of satellite cell activity is also a cause of sarcopenia. We tested this hypothesis in male sedentary mice by experimentally depleting satellite cells in young adult animals to a degree sufficient to impair regeneration throughout the rest of their lives. A detailed analysis of multiple …

Importance Of Livestock Production From Grasslands For National And Local Food And Nutritional Security In Developing Countries, Iain A. Wright

IGC Proceedings (1977-2023)

Grazing lands cover more than a quarter of the world’s land surface, often on land that is unsuitable for other forms of use. Despite the perception that productivity is inherently low, the contribution of grasslands in food security in developing countries is significant. However the challenges of spatial and temporal variability of primary productivity need to be managed and mobility of livestock is key to this. Appropriate land management and governance arrangements are essential for facilitating this mobility and for creating the circumstances in which technical options for reducing variability and risk in livestock keeping can be deployed and to …

The National Cancer Institute’S Community Networks Program Initiative To Reduce Cancer Health Disparities: Outcomes And Lessons Learned, Kathryn L. Braun, Susan Stewart, Claudia Baquet, Lisa Berry-Bobovski, Daniel Blumenthal, Heather M. Brandt, Dedra S. Buchwald, Janice E. Campbell, Kathryn Coe, Leslie C. Cooper, Paula Espinoza, Ronda Henry-Tillman, Margaret Hargreaves, Aimee James, Judith Salmon Kaur, K. Viswanath, Grace X. Ma, Jeanne Mandelblatt, Cathy Meade, Amelie Ramirez, Isabel Scarinci, Sora Park Tanjasiri, Beti Thompson, Anissa I. Vines, Mark Dignan

Internal Medicine Faculty Publications

Background: We describe reach, partnerships, products, benefits, and lessons learned of the 25 Community Network Programs (CNPs) that applied community-based participatory research (CBPR) to reduce cancer health disparities.

Methods: Quantitative and qualitative data were abstracted from CNP final reports. Qualitative data were grouped by theme.

Results: Together, the 25 CNPs worked with more than 2,000 academic, clinical, community, government, faith-based, and other partners. They completed 211 needs assessments, leveraged funds for 328 research and service projects, trained 719 new investigators, educated almost 55,000 community members, and published 991 articles. Qualitative data illustrated how use of CBPR improved …

Characterization Of Two Biochars Derived From Horse Muck And Their Ability To Reduce Pathogen Transport In Soil, David Griffith

Theses and Dissertations--Biosystems and Agricultural Engineering

Biochars have been created and characterized from a variety livestock manure biomass including poultry, dairy, and swine. However, no research has been conducted on the physical and chemical makeup of biochar pyrolyzed from horse muck. Two horse muck derived biochars containing either straw (HS) or woodchip (HW) bedding were pyrolyzed at 700°C and characterized for their physical and chemical properties. Tests revealed both biochars had high alkalinity, moderate specific conductivity, and low surface area as compared to other biochars in the literature. HS contained more mineral structures than HW. Scanning electron microscopy presented differences in particle shape, size, and presence …

Towards Intelligent Telerobotics: Visualization And Control Of Remote Robot, Bo Fu

Theses and Dissertations--Computer Science

Human-machine cooperative or co-robotics has been recognized as the next generation of robotics. In contrast to current systems that use limited-reasoning strategies or address problems in narrow contexts, new co-robot systems will be characterized by their flexibility, resourcefulness, varied modeling or reasoning approaches, and use of real-world data in real time, demonstrating a level of intelligence and adaptability seen in humans and animals. The research I focused is in the two sub-field of co-robotics: teleoperation and telepresence. We firstly explore the ways of teleoperation using mixed reality techniques. I proposed a new type of display: hybrid-reality display (HRD) system, which …

Living On The Edge: Rethinking Pueblo Period: (Ad 700 – Ad 1225) Indigenous Settlement Patterns Within Grand Canyon National Park, Northern Arizona, Philip B. Mink Ii

Theses and Dissertations--Anthropology

This dissertation challenges traditional interpretations that indigenous groups who settled the Grand Canyon during the Pueblo Period (AD 700 -1225) relied heavily on maize to meet their subsistence needs. Instead they are viewed as dynamic ecosystem engineers who employed fire and natural plant succession to engage in a wild plant subsistence strategy that was supplemented to varying degrees by maize. By examining the relationship between archaeological sites and the natural environment throughout the Canyon, new settlement pattern models were developed. These models attempt to account for the spatial distribution of Virgin people, as represented by Virgin Gray Ware ceramics, Kayenta …

Analyzing Charges And Payments Received For Discharged Patients At Teaching Hospitals In Relation To Patient Satisfaction And Overall Medicare Charges, Rob Sutter

MPA/MPP/MPFM Capstone Projects

The affordability of healthcare is a major, recurring topic in the media. One of President Obama’s cornerstone policies has been the attempt to make health care affordable. Part of the concern lies in cost differences for similar procedures. The cost for a standardized procedure such as abnormal cardiac dysrhythmia without complication varies greatly between hospitals. The cost difference of a patient getting treated for such an event can be an average of $30,000 depending on which hospital you go to. There is no immediately apparent reason for such a large difference. Another noticeable item is that all the hospitals receive …

Impaired Glucose Metabolism In The Absence Of Skeletal Muscle Brain And Muscle Arnt-Like-Protein 1 (Bmal1), Brianna D. Harfmann

Theses and Dissertations--Physiology

Metabolism is a critical physiological function that works to generate energy for cells, store substrates and maintain homoeostasis. Alterations in normal metabolism can have a severe effect on physiology, leading to metabolic disease. Skeletal muscle is a key metabolic tissue, taking up ~80% of postprandial glucose. Therefore it contributes considerably to glucose metabolism: glucose uptake, oxidation and homeostasis. To address the role of the skeletal muscle clock in insulin sensitivity and glucose tolerance, our lab generated an inducible skeletal muscle specific Bmal1^-/- mouse (iMSBmal1^-/-). 5 weeks post-recombination we observed impairment in both insulin- and AICAR-stimulated skeletal …

Parent Involvement And Science Achievement During Students’ Transition Years From Elementary School To Middle School: A Cross-Lagged Panel Analysis Using Ecls-K, Letao Sun

Theses and Dissertations--Educational Policy Studies and Evaluation

Transitioning from elementary school to middle school can be a difficult time for many adolescents. It is a period often correlated with a decline in students’ academic achievement, perceptions of performance, potential, and value in schooling. Research has shown evidence that parents’ involvement in their children’s education significantly influences children’s academic achievement. However, there are many conflicting findings regarding this relationship.

The primary purpose of this study is to extend existing research on academic achievement by examining the causal relationship between parent involvement and science achievement during the transition years, using data from the Early Childhood Longitudinal Study, Kindergarten Class …

“Taking The Stairs” To Break The Ceiling: Understanding Students’ Conceptions Of The Intersections Of Historical Agency, Gender Equity, And Action, Lauren M. Colley

Theses and Dissertations--Education Sciences

The present quasi-naturalistic study used socio-cultural theory (Wertsch, 1998), picture theory (Mitchell, 1994) and the use of historical agency as a second-order concept (Lee & Ashby, 2000; Seixas & Morton, 2013) as a way of examining the historical thinking of high school seniors as they investigated second-wave feminism. Existing literature reflects the ways in which students understand historical agency (Barton, 1997; Winter, 2001; Peck, Poyntz, & Seixas, 2011), but has yet to examine its use as a conceptual tool to dissect controversial issues in history, such as feminism. The main research question was: in what ways do high school seniors …

Missed Opportunities In The Mountains: The University Of Kentucky's Action Program In Eastern Kentucky In The 1960s, Bradley L. Goan

Theses and Dissertations--Educational Policy Studies and Evaluation

This dissertation explores the University of Kentucky’s efforts to develop and implement an “action program” in eastern Kentucky in the 1960s. By the late 1950s, Kentucky’s political, business, and academic leaders had identified eastern Kentucky as the state’s problem area, and they sought strategies to bring the region into the economic and cultural mainstream. This generation of post-war leaders had an uncompromising faith in the power of knowledge, technology, and planning, and University leaders saw their action program as a university-wide effort to address what most would argue was Kentucky’s ugliest problem. This study begins with an examination of the …

Generational Differences In Transfer Student Capital Among Community College Students, Michael J. Rosenberg

Theses and Dissertations--Educational Policy Studies and Evaluation

“Transfer student capital” refers to the learned ability of a student to successfully navigate the process of transferring from a community college to a four-year school. Transfer student capital is accumulated by gathering information about potential destination schools and programs, gaining an understanding of requisite academic skills, campus engagement, and weighing personal concerns surrounding eventual transfer. The more transfer student capital an individual accumulates, the more likely they are to be academically successful and persist to graduation.

This quantitative study examines whether a student’s age cohort may affect the transfer process from community college to a four-year school. The study …

Gender Discrimination And Title Ix Implementation: Lessons From The Office For Civil Rights Resolution Letters 1997-2011, Laura S. Johnson

Theses and Dissertations--Educational Policy Studies and Evaluation

Gender discrimination, such as sexual harassment, sexual assault and inequitable treatment has long been considered a prominent issue on higher education campuses and is regulated under the Patsy Takemoto Mink Equal Opportunity in Education Act, commonly known as Title IX. Title IX is enforced by the Department of Education’s Office for Civil Rights (OCR) who responds to gender discrimination complaints on campus through investigations resulting in what are called OCR Resolution Letters. These letters define numerous policies and procedures Institutions of Higher Education (IHE) must put in place pertaining to the prevention of gender discrimination. This qualitative study looks specifically …

The Use Of A Digital Game-Based Safety Program For All-Terrain Vehicles: Operational Knowledge For Youthful Riders, Mark Schneider

Theses and Dissertations--Curriculum and Instruction

Given the exposure and preference of digital natives for games, along with the proliferation of digital devices, there is a need to determine how effective digital games are in conveying operational knowledge to our youth. This quasi-experimental study examined whether a digital safety game increased high school student operational knowledge of All-terrain Vehicle (ATV) safety in contrast to conventional PowerPoint ATV safety training with commensurate information. The first treatment group consisted of “in class” students participating in the ATV game, the second treatment group was made up of “free play” students playing the game out of class, and finally the …

The Effect Of Music Therapy Interaction On Child And Parental Preoperative Anxiety In Parents Of Children Undergoing Day Surgery, Christopher R. Millett

Theses and Dissertations--Music

Young children who experience high levels preoperative anxiety often exhibit distress behaviors, experience more surgical complications, and are at a higher risk for developing a variety of negative postoperative consequences. A significant factor in pediatric preoperative anxiety is the level of anxiety present in their caregivers. Music therapy interventions addressing a variety of procedural outcomes have been met with success. The purpose of this study was to investigate the comparative effectiveness of two music therapy interventions on reducing preoperative anxiety in young pediatric surgical patients and their caregivers.

A total of 40 pediatric patient and caregiver dyads were included in …

Creative Treatment Of Folk Melodies In Selected Cirandinhas And Cirandas Of Heitor Villa-Lobos, Eldia Carla Farias

Theses and Dissertations--Music

This study provides a comparative analysis and performance suggestions for three Cirandinhas and three Cirandas for solo piano by Heitor Villa-Lobos in order to demonstrate their aesthetic and pedagogical value. The primary objective is to argue for the significance of the Cirandas as concert works and of the Cirandinhas as didactic ones. To better explore these two sets of pieces and their interconnections, the selected Ciranda-Cirandinhas pairs are all based on the same folksong theme. Thus, the analyses also demonstrate Villa-Lobos’s desire to represent Brazilian culture through his music and the ingenuity with which he treated the same melodic material …

More Than Death: Fear Of Illness In American Literature 1775-1876, Sarah Schuetze

Theses and Dissertations--English

This dissertation argues that eighteenth- and nineteenth-century narratives about personal and collective experiences with disease train American readers to fear illness while warning them against the dangers of being afraid. Such narratives depict the way illness ravages the physical body, disrupts interpersonal relationships, and threatens to dismantle social or municipal organization. In other words, the story of sickness is a story of terror-inducing dis-order. I study disease with a lens informed by cultural and disability studies to show that what makes disease historically and culturally significant is its power—through the body—to dis-order relationships, society, and knowledge. Anxieties about this dis-order …