Digital Commons Network^™

Evaluating The Physics-Based Slope Stability Program Pisa-M At A Regional Scale, Hudson J. Koch, William C. Haneberg, Matt M. Crawford, Jason M. Dortch, Meredith Swallom

Report of Investigations--KGS

Physics based landslide modeling can be difficult and data intensive. Generating high quality and practical map results is often not feasible outside of small, thoroughly characterized study areas. Using the physics based program Probabilistic Infinite Slope Analysis (PISA m), users can perform expedient assessments of landslide hazard over large study areas where comprehensive geotechnical data may be lacking, but other data inputs are robust. PISA m uses an infinite slope equation and spatial layers, such as a digital elevation model (DEM), a lidar derived forest cover layer, and a soil map, to calculate the probability that the factor of safety …

A Comparative Study Of Electronic And Paper Ballot Systems In Modern U.S. Elections, Gianna M. Wadowski, Nicholas D. Bernardo, Bridgett A. King, Gretchen A. Macht

Political Science Faculty Publications

In-person voting processes that rely on paper ballots have long dominated voting processes in the United States. However, following the implementation of the Help America Vote Act in 2002, states rapidly adopted new voting technologies that dramatically changed the in-person voting experience. Since then, states have continued to adopt new voting technologies as new challenges and opportunities have emerged. Although scholarship has demonstrated that new voting technologies can offer benefits, reported improvements to the in-person voting experience are inconsistent. Despite changes in voting equipment and voting methods, voters continue to wait in long lines, affecting turnout and voter confidence. Using …

Crystal Structure And Hirshfeld-Surface Analysis Of The Pesticide Etoxazole, Chaluvarangaiah Sowbhagya, Thaluru M.Mohan Kumar, Hemmige S. Yathirajan, Sean Parkin

Chemistry Faculty Publications

Etoxazole (C21H23F2NO2), systematic name 4-(4-tert-butyl-2-ethoxyphenyl)-2- (2,6-difluorophenyl)-4,5-dihydro-1,3-oxazole, is a fluorinated insecticide and acaricide that inhibits chitin biosynthesis, disrupting insect development by preventing proper exoskeleton formation. Widely used in agriculture since 1998, it is readily absorbed by plant tissues and translocates within leaves. Metabolic studies have identified several oxidative degradation products, while toxicological assessments have examined potential effects, including oxidative stress. This study presents a detailed crystallographic and Hirshfeld surface analysis of etoxazole. The molecule consists of a central dihydro-oxazole ring flanked by 2,6-difluorophenyl and 4-tert-butyl-2-ethoxyphenyl groups, each twisted relative to the oxazole core. The dihydro-oxazole ring is nearly planar, with the …

Comparison Of Incisional Hernia Rates Between General And Gynecological Surgery Procedures, Krista Spear, Daniel L. Davenport, Lance Butler, Margaret Plymale, John Scott Roth

Surgery Faculty Publications

Background and Objectives: Incisional hernias are a common and costly complication of surgery, occurring in up to 20% of midline incisions within 3 years of initial operation. Risk factors for incisional hernia include incision site, fascial closure technique, body mass index (BMI), surgical site infections, and gastrointestinal surgery. Limited studies have compared procedural type as a risk factor for hernia formation. The goal of this study was to examine incisional hernia rates among general surgical and gynecologic procedures. Materials and Methods: We queried our Research Data Warehouse for inpatients who had undergone common open abdominal surgeries between January 2012 and …

Atp-Sensitive Potassium Channels Alter Glycolytic Flux To Modulate Cortical Activity And Sleep, Nicholas J. Constantino, Caitlin M. Carroll, Holden C. Williams, Hemendra J. Vekaria, Carla M. Yuede, Kai Saito, Patrick W. Sheehan, J. Andy Snipes, Marcus E. Raichle, Erik S. Musiek, Patrick G. Sullivan, Josh M. Morganti, Lance A. Johnson, Shannon L. Macauley

Physiology Faculty Publications

Metabolism plays a key role in the maintenance of sleep/wake states. Brain lactate fluctuations are a biomarker of sleep/wake transitions, where increased interstitial fluid (ISF) lactate levels are associated with wakefulness and decreased ISF lactate is required for sleep. ATP-sensitive potassium (K_ATP) channels couple glucose-lactate metabolism with excitability. Using mice lacking K_ATP channel activity (e.g., Kir6.2^−/− mice), we explored how changes in glucose utilization affect cortical electroencephalography (EEG) activity and sleep/wake homeostasis. In the brain, Kir6.2^−/− mice shunt glucose toward glycolysis, reducing neurotransmitter biosynthesis and dampening cortical EEG activity. Kir6.2^−/− mice spent more time …

Sowing The Seeds Of Confusion To Reap Content Mastery, Rebecca Mcgrail

Greater Faculties: A Review of Teaching and Learning

No abstract provided.

Getting Students Excited About Chemistry, Jovita Daraezinwa

Greater Faculties: A Review of Teaching and Learning

No abstract provided.

Overcoming Students' Resistance To The Flipped Classroom, Koji Tanno

Greater Faculties: A Review of Teaching and Learning

No abstract provided.

Zines: Radical Tools For Empathy And Introspection, Aanya Chugh

Greater Faculties: A Review of Teaching and Learning

No abstract provided.

Deformation And Collectivity In Doubly Magic Pb 208, J. Henderson, J. Heery, M. Rocchini, M. Siciliano, N. Sensharma, A. D. Ayangeakaa, R. V.F. Janssens, T. M. Kowalewski, Abhishek, P. D. Stevenson, E. Yüksel, B. A. Brown, T. R. Rodriguez, L. M. Robledo, C. Y. Wu, S. Kisyov, C. Müller-Gatermann, V. Bildstein, L. Canete, C. M. Campbell, S. Carmichael, M. P. Carpenter, W. N. Catford, P. Copp, C. Cousins, M. Devlin, D. T. Doherty, P. E. Garrett

Chemistry Faculty Publications

Lead-208 is the heaviest known doubly magic nucleus and its structure is therefore of special interest. Despite this magicity, which acts to provide a strong restorative force toward sphericity, it is known to exhibit both strong octupole correlations and some of the strongest quadrupole collectivity observed in doubly magic systems. In this Letter, we employ state-of-the-art experimental equipment to conclusively demonstrate, through four Coulomb-excitation measurements, the presence of a large, negative, spectroscopic quadrupole moment for both the vibrational octupole 31- and quadrupole 21+ state, indicative of a preference for prolate deformation of the states. The observed quadrupole moment is discussed …

Dysregulated Alveolar Epithelial Cell Progenitor Function And Identity In Hermansky-Pudlak Syndrome, Joanna Y. Wang, Sylvia N. Michki, Sneha Sitaraman, Brandon J. Banaschewski, Reshma Jamal, Jason J. Gokey, Susan M. Lin, Jeremy B. Katzen, Maria C. Basil, Edward Cantu, Jonathan A. Kropski, Jarod A. Zepp, David B. Frank, Lisa R. Young

Surgery Faculty Publications

Hermansky-Pudlak syndrome (HPS) is a genetic disorder of endosomal protein trafficking associated with pulmonary fibrosis in specific subtypes, including HPS-1 and HPS-2. Single-mutant HPS1 and HPS2 mice display increased fibrotic sensitivity while double-mutant HPS1/2 mice exhibit spontaneous fibrosis with aging, which has been attributed to HPS mutations in alveolar epithelial type II (AT2) cells. We utilized HPS mouse models and human lung tissue to investigate mechanisms of AT2 cell dysfunction driving fibrotic remodeling in HPS. Starting at 8 weeks of age, HPS mice exhibited progressive loss of AT2 cell numbers. HPS AT2 cell function was impaired ex vivo and in …

Current Practices In Rock Scaling, Daryl J. Greer, Kean H. Ashurst Jr

Kentucky Transportation Center Research Report

Rockfalls, which result from the chemical and physical weathering of aging exposed rock cuts, occur frequently along many Kentucky roadways and can endanger travelers. Mitigating rockfalls often requires substantial excavation, procuring additional right of way, and/or hiring specialty contractors. An alternative to these expensive processes is rock scaling, which can be a cost-effective tool for mitigating rockfalls. Rock scaling entails removing loose and unstable rocks from rock cut slopes within the right of way to reduce rockfall risk and is being used with increased frequency by state transportation agencies around the country. The Kentucky Transportation Cabinet (KYTC) has completed several …

Gestational Weight Gain And Increased Risk Of Cesarean Delivery Across Body Mass Index Categories., Pearl A Mcelfish, Britni L Ayers, Nicola L Hawley, Aaron Caldwell, Austin Porter, Michael D Macechko, Donya Watson, Jennifer A Callaghan-Koru, James P Selig, Jennifer A Andersen, Nirvana Manning, Lanita White, Enrique Gomez-Pomar, Clare C Brown

Pediatrics Faculty Publications

BACKGROUND: Unnecessary cesarean delivery can have negative implications for both mothers and infants. In the United States, the proportion of women undergoing cesarean delivery exceeds the acceptable World Health Organization proportion. Reducing cesarean deliveries is a national goal of Centers for Disease Control and Prevention Healthy People 2030, the American College of Obstetricians and Gynecologists, and the Alliance for Innovation on Maternal Health.

OBJECTIVE: This study aimed to examine if excessive gestational weight gain is associated with increased risk of cesarean delivery across multiple body mass index categories.

STUDY DESIGN: Analysis was conducted using vital records data from the National …

Investigating Suicide Risk Factors Among Appalachian West Virginian Adults, Erin D. Caswell, Angela M. Dyer, Summer D. Hartley, Caroline P. Groth, Mary Christensen, Sahiti K. Tulabandu, Bryce K. Weaver, Ruchi Bhandari

Journal of Appalachian Health

Introduction: Suicide rates in the United States have increased over the past two decades, with rural areas, particularly the Appalachian Region, facing unique challenges that elevate suicide risk. These include economic hardships, social isolation, and limited access to mental health services.

Purpose: This study addresses critical gaps in understanding lifetime suicide risk in West Virginia (WV), a predominantly rural state entirely within the Appalachian Region. By identifying the factors driving urban-rural differences in suicide risk, this research seeks to inform interventions tailored to the state's distinct needs and provide insights applicable to the broader Appalachian Region

Methods: Using 2021 Mountain …

Comparative Outcomes Following Randomization To A Pilot Facebook-Based Hiv Prevention Intervention Among Appalachian Women Involved In The Criminal Legal System, Megan F. Dickson, Erika Pike, Michele Staton

Journal of Appalachian Health

Introduction: Rural Appalachian women who use drugs and are involved in the criminal legal system are at increased risk for health consequences (such as HIV/Hepatitis C). Service barriers throughout rural communities have prompted a need to examine the effectiveness of novel intervention delivery methods (e.g., social media).

Purpose: This study aims to determine if enhancing an existing HIV prevention intervention with additional modules delivered via Facebook improves service access by examining short-term outcomes among Appalachian women returning to the community following jail release.

Methods: Between 2019 and 2022, consenting women from two rural Appalachian jails were randomly selected, screened, interviewed, …

Rural Reflections Of Appalachia: A Qualitative Study Of Health Professional Students’ Experiences From A Rural Immersion Experience In West Virginia, Treah Haggerty Md Ms, Jessica Stidham Ma, Stephan Brooks Mph, Abigail Cowher Ba, Sandra Pope Msw, Patricia Dekeseredy Mscn Rn, Cara L. Sedney Md,Ma

Journal of Appalachian Health

Introduction: Conventional academic rotations lack in-depth exposure to rural community members, systems, and resources surrounding specific rural-focused health issues.

Purpose: This study aims to explore health professional students’ experiences within a community-based multidisciplinary rural immersion through their personal reflections.

Methods: Written reflective entries were extracted from the online classroom system from 2019–2021. Data analysis was guided by thematic analysis. An iterative process of qualitatively coding the interviews was conducted. Themes were reviewed and agreed upon by consensus and assessed for validity by two senior researchers.

Results: Sixty-two reflective essays were included from 11 unique professional programs. Resulting themes included (1) …

Milk Yield Of Cows With Different Genetic Potential On Grass And Grass-Legume Tropical Pastures, C E. Lascano, P Avila

IGC Proceedings (1977-2023)

A grazing experiment was carried out at CIAT's Quilichao research station to assess the effect of legumes selected for acid soils on milk production of cows with different genetic potential. Pastures of Brahiaria dictyoneura cv. Llanero and Andropogen gayanus cv. Carimagua l, alone and in association with Centrosema acutifolium (CIAT 5568) and C. macrocarpum (CJAT 5713), were grazed by Holstein and Zebu crossbred cows using a Latin square crossover design. Fat corrected milk (FCM) yield of Holstein cows was 17 and 19% higher in the associations of B. dictyoneura and A. gayanus, respectively, than in the grass-only pastures. With the …

Feed Resources For Intensive Smallholder Systems In The Tropics: The Role Of Crop Residue, O B. Smith

IGC Proceedings (1977-2023)

The paper focuses on smallholder production systems in the tropics, characterised not so much by the land holding or livestock numbers, which may vary from one ecozone to another, but rather by an integrated crop-livestock production system, which appears to be the common thread among smallholder producers across all ecozones of the tropics. A major advantage of such a system is the production of large quantities of crop residues on-farm. These residues have the potential to contribute significantly to feed requirements. Paradoxically, the major constraint facing this system is a perennial quantitative and qualitative feed shortage which is most manifest …

Attainment And Distribution Of Competitive Equilibrium In Tropical Grass-Legume Mixtures, P G. Tow

IGC Proceedings (1977-2023)

An experiment under controlled conditions, using the de Wit competition model, has provided an explanation of competitive relationships in mixtures of Panicum maximum var. trichoglume (green panic) cv. Petrie and Neontonia wightii cv. Tinaroo glycine. Experiments in a tropical upland environment with summer rainfall dominance (to which they ore adapted) have provided further understanding of their relationships. Over a period of 2 years for well-wafered plants in containers and 4 years in a rain-fed field experiment, competitive gains by one species alternated with-gains by the other, and neither species gained significantly overall. Gains by the grass were favoured by …

Complex Tissue Regeneration In Lophuromys Reveals A Phylogenetic Signal For Enhanced Regenerative Ability In Deomyine Rodents, Brennan Riddell, Molly Mcdonough, Adam Ferguson, John M. Kimani, Thomas R. Gawriluk, Chi Peng, Stephen G. Kiama, Vanessa O. Ezenwa, Ashley W. Seifert

Biology Faculty Publications

Identifying why complex tissue regeneration is present or absent in specific vertebrate lineages has remained elusive. One also wonders whether the isolated examples where regeneration is observed represent cases of convergent evolution or are instead the product of phylogenetic inertia from a common ancestral program. Testing alternative hypotheses to identify genetic regulation, cell states, and tissue physiology that explain how regenerative healing emerges in some species requires sampling multiple species among which there is variation in regenerative ability across a phylogenetic framework. Here, we interrogate tissue healing across eleven rodents and show that brush-furred mice (Lophuromys zena) are capable of …

Land Use Change Consistently Reduces Α- But Not Β- And Γ-Diversity Of Bees., Toby P N Tsang, A A Amado De Santis, Gabriela Armas-Quiñonez, John S Ascher, Eva Samanta Ávila-Gómez, András Báldi, Kimberly M Ballare, Mario V Balzan, Weronika Banaszak-Cibicka, Svenja Bänsch, Yves Basset, Adam J Bates, Jessica M Baumann, Mariana Beal-Neves, Ashley Bennett, Antonio Diego M Bezerra, Betina Blochtein, Riccardo Bommarco, Berry Brosi, Laura A Burkle, Luísa G Carvalheiro, Ignacio Castellanos, Marcela Cely-Santos, Hamutahl Cohen, Drissa Coulibaly, Saul A Cunningham, Sarah Cusser, Isabelle Dajoz, Deborah A Delaney, Ek Del-Val, Monika Egerer, Markus P Eichhorn, Eunice Enríquez, Martin H Entling, Natalia Escobedo-Kenefic, Pedro Maria Abreu Ferreira, Gordon Fitch, Jessica R K Forrest, Valérie Fournier, Robert Fowler, Breno M Freitas, Hannah R Gaines-Day, Benoît Geslin, Jaboury Ghazoul, Paul Glaum, Jose L Gonzalez-Andujar, Adrian González-Chaves, Heather Grab, Claudio Gratton, Solène Guenat, Catalina Gutiérrez-Chacón, Mark A Hall, Mick E Hanley, Annika Hass, Ernest Ireneusz Hennig, Martin Hermy, Juliana Hipólito, Andrea Holzschuh, Sebastian Hopfenmüller, Keng-Lou James Hung, Kristoffer Hylander, Jordi Izquierdo, Mary A Jamieson, Birgit Jauker, Steve Javorek, Shalene Jha, Björn K Klatt, David Kleijn, Alexandra-Maria Klein, Anikó Kovács-Hostyánszki, Jochen Krauss, Michael Kuhlmann, Patricia Landaverde-González, Tanya Latty, Misha Leong, Susannah B Lerman, Yunhui Liu, Ana Carolina Pereira Machado, Anson Main, Rachel Mallinger, Yael Mandelik, Bruno Ferreira Marques, Kevin Matteson, Frédéric Mccune, Ling-Zeng Meng, Jean Paul Metzger, Paula María Montoya-Pfeiffer, Carolina Morales, Lora Morandin, Jane Morrison, Sonja Mudri-Stojnić, Pakorn Nalinrachatakan, Olivia Norfolk, Mark Otieno, Mia G Park, Stacy M Philpott, Gideon Pisanty, Montserrat Plascencia, Simon G Potts, Eileen F Power, Kit Prendergast, Robyn D Quistberg, Davi De Lacerda Ramos, André Rodrigo Rech, Victoria Reynolds, Miriam H Richards, Stuart P M Roberts, Malena Sabatino, Ulrika Samnegård, Hillary Sardiñas, Karina Sánchez-Echeverría, Fernanda Teixeira Saturni, Jeroen Scheper, Amber R Sciligo, C Sheena Sidhu, Brian J Spiesman, Tuanjit Sritongchuay, Ingolf Steffan-Dewenter, Katharina Stein, Alyssa B Stewart, Jane C Stout, Hisatomo Taki, Pornpimon Tangtorwongsakul, Caragh G Threlfall, Carla Faleiro Tinoco, Teja Tscharntke, Katherine J Turo, Chatura Vaidya, Rémy Vandame, Carlos H Vergara, Blandina F Viana, Eric Vides-Borrell, Natapot Warrit, Elisabeth Webb, Catrin Westphal, Jennifer B Wickens, Neal M Williams, Nicholas S G Williams, Caleb J Wilson, Panlong Wu, Elsa Youngsteadt, Yi Zou, Lauren C Ponisio, Timothy C Bonebrake

Entomology Faculty Publications

Land use change threatens global biodiversity and compromises ecosystem functions, including pollination and food production. Reduced taxonomic α-diversity is often reported under land use change, yet the impacts could be different at larger spatial scales (i.e., γ-diversity), either due to reduced β-diversity amplifying diversity loss or increased β-diversity dampening diversity loss. Additionally, studies often focus on taxonomic diversity, while other important biodiversity components, including phylogenetic diversity, can exhibit differential responses. Here, we evaluated how agricultural and urban land use alters the taxonomic and phylogenetic α-, β-, and γ-diversity of an important pollinator taxon-bees. Using a multicontinental dataset of 3117 bee …

Advancing Workforce Development And Scientific Collaboration, Emily Slade, Claudine T. Jurkovitz, Shari Messinger, Robert A. Oster, Gina Maria Pomann, Sandra L. Taylor, Ann M. Brearley

Biostatistics Faculty Publications

A clinical and translational scientist (CTS) often seeks to increase their knowledge of statistical topics to effectively conduct biomedical research studies. A common method for obtaining this knowledge is through existing online educational materials that are suggested by a biostatistical collaborator or identified by the CTS. However, the volume of available educational materials on diverse statistical topics makes the task of identifying high-quality educational resources at an appropriate level challenging and time consuming for CTSs and collaborative biostatisticians. In response to these challenges, the Biostats4You website was created, where existing online educational materials for a variety of statistical topics are …

Parents Who Make America Great Again: Identity Politics In Right-Wing Populist Discourses On Gender Ideology And Immigration, Alina Hechler

Theses and Dissertations--Gender and Women's Studies

This dissertation explores how anti-immigration and anti-(trans)gender campaigns in the United States engage in an identity politics in which a group benefiting from heteronormative, white supremacist, and nationalist social structures discursively positions itself as an oppressed minority facing an elitist, oppressive, and parasitic establishment. While anti-transgender and anti-immigration platforms represent two distinct issues, they need to be situated within the broader context of right-wing politics. With a focus on the construction of parenthood, my dissertation juxtaposes these two forms of right-wing campaigns through a mixed-method approach by tracing the depiction of two parental figures that have recently emerged in right-wing …

Lagrange Multipliers As A Metric For Early-Stage Shipboard Power System Design, Magdalen A. Barnes

Theses and Dissertations--Electrical and Computer Engineering

Integrated power systems are essential in the operation of electric ships and must function under a diverse range of conditions. In addition to routine operation, ships should be prepared to respond to challenging events that require significant amounts of power. Demanding scenarios, coupled with complex and interconnected power systems, present challenging issues. The power and energy ratings of equipment are crucial factors in the operational success of the ship; however, to meet economic constraints, balance between performance and cost must be upheld. Details regarding equipment models and specifications are typically unavailable during early-stage design. Power system modeling and simulation can …

Energy Dependence Of Polarized Γγ → E+E− In Peripheral Au + Au Collisions At √Snn = 54.4 And 200 Gev With The Star Experiment At Rhic, Star Collaboration

Physics and Astronomy Faculty Publications

We report the differential yields at mid-rapidity of the Breit-Wheeler process (γ γ → e+e−) in peripheral Au + Au collisions at √s NN = 54.4 and 200 GeV with the STAR experiment at the Relativistic Heavy Ion Collider (RHIC), as a function of energy √s NN , e+e− transverse momentum pT , p2 T , invariant mass Mee, and azimuthal angle. In the invariant mass range of 0.4 < Mee < 2.6 GeV/c2 at low transverse momentum (pT < 0.15 GeV/c), the yields increase while the pair √〈p2 T〉 decreases with increasing √s NN , a feature that is correctly predicted by the QED calculation. The energy dependencies of the measured quantities are sensitive to the nuclear form factor, infrared divergence and photon polarization. The data are compiled and used to extract the charge radius of the Au nucleus.

Smart Homes, Grids, And Electric Vehicles Large-Scale Integration Studies Employing Machine Learning And Optimization Techniques, Rosemary E. Alden

Theses and Dissertations--Electrical and Computer Engineering

Residential digital twins are fundamental to the smart grid transition, and thus, must be both accurate and representative of existing homes and scalable for large distribution systems. Within this dissertation, new machine learning (ML) and physics-based methodologies are applied to the major individual residential loads, energy storage devices, and resources in the US to develop computationally efficient digital twins and new optimal control strategies for the virtual power plant (VPP) concept. Big data from experimental field demonstrations with dedicated metering, thousands of residential smart meter profiles, and large national human behavior surveys are employed to develop ultra-fast scalable residential load …

Feasibility Of An Lgbtq+ Public Health Surveillance Platform In Kentucky: A Brief Report On Mental Health Signals, Keith J. Watts, Sydney Howard, Missy Spears, Carolyn Lauckner, Rachel H. Farr, Glenn Means, Justin X. Moore

Social Work Faculty Publications

Background/Objectives: Robust, state-level LGBTQ+ health surveillance is scarce in Kentucky, limiting evidence-based healthcare planning and policy. We aimed to evaluate the feasibility and early public-health utility of a community-partnered annual survey and compare selected mental health stressors between Kentucky and non-Kentucky respondents.

Methods: We conducted a cross-sectional online survey (13 April–15 July 2024) developed with a statewide LGBTQ+ nonprofit. Recruitment occurred via organizational channels and community events. A content warning preceded the survey, which was administered via Qualtrics. Data quality was screened using reCAPTCHA. We assessed feasibility metrics including recruitment and completion rates. Mental health stressors were captured …

Examining The Psychometric Properties Of The Classroom Whiteness Scale (Claws) Through Rasch Partial Credit Analysis, Jaylene T. Patterson

Theses and Dissertations--Educational, School, and Counseling Psychology

This pilot study examines how whiteness manifests in K-12 classrooms by developing and evaluating the Classroom Whiteness Scale (ClaWS), an instrument designed to assess in-service teachers’ salience and engagement with whiteness-informed practices. ClaWS consists of 21 items across two subscales: one measuring the salience of whiteness-related beliefs in teachers’ pedagogical decisions and the other capturing the frequency of these practices in classroom settings. Rooted in critical whiteness studies, the scale operationalizes key dimensions of whiteness, including ethnocentric monoculturalism, white standardization, white silence, right to comfort, white saviorism, and colorblind racial ideology.

Using Rasch Partial Credit Model (RPCM) analysis, this study …

Developing Novel Therapeutic Strategies For Mcrc With A Brafv600e Mutation, Mariah Geisen

Theses and Dissertations--Toxicology and Cancer Biology

Colorectal cancer (CRC) is the second leading cause of cancer death worldwide. The overall incidence rates of CRC have decreased in those over 50, but there is an increasing incidence rate in those under 50. Risk factors for CRC include diet, family history, and a sedentary lifestyle. Early detection of CRC is key to patient survival and treatment response. Localized CRC has a survival rate of 90% and allows for surgical resection and chemotherapy. The 5-year survival for metastatic CRC (mCRC) is significantly reduced to around 14%. Despite early detection, 50% of patients will develop metastasis after surgical resection and …

Forage News [2025-08], University Of Kentucky

Forage News

No abstract provided.