Digital Commons Network^™

Particle Size And Temperature Affect Fecal Bacteria Survival In Sediment, Mark S. Coyne, J. M. Howell, P. L. Cornelius

Agronomy Notes

When cattle have direct access to streams, fecal bacteria concentrations in stream sediments increase. If these bacteria persist, and if the sediments are resuspended, fecal bacteria may also appear in surrounding water for extended periods. Why do fecal bacteria persist, since dry conditions, high acidity or alkalinity, sunlight, competition from native microbes, and extreme temperatures all diminish their populations in soil? The effects of these environmental factors are much reduced in sediment. Water protects fecal bacteria from desiccation and ultraviolet light. High temperatures can promote their regrowth in wet environments. Fecal bacteria also survive on fine-sized sediments in streams because …

Soil Management For Intensive Grazing, Kenneth L. Wells, Charles T. Dougherty

Soil Science News and Views

Recycling of plant nutrients is of major concern in managing paddocks in pasturefields for intensive grazing. Redistribution of nutrients present in fecal and urine deposits is an important issue in growing climatically and seasonally-adapted forage species and for efficient conversion of herbage into animal products while adding to the sustainability of the system. Some of the questions that arise in managing soils for intensive grazing are discussed below.

Genetics, Genetic Testing, And The Specter Of Discrimination: A Discussion Using Hypothetical Cases, Richard H. Underwood, Ronald C. Cadle

Law Faculty Scholarly Articles

A "genetic revolution" is upon us. Techniques for genetic testing have increased in sophistication, and an international effort to map and sequence human DNA—The Human Genome Project ("HGP")—is now well under way. We are beginning to exploit our new found genetic knowledge. Recognition of the relationship between developments in genetic science, law, and public policy, is creeping into the "literature" and into the law school curriculum. Even the popular 60 Minutes television "news magazine" recently did a program on the perils of genetic testing. Still, for lawyers and policymakers at least, the material is not all that accessible.

The following …

"We Have Raffeled For The Elephant & Won!": The Wool Industry At South Union, Kentucky, Donna Parker, Jonathan Jeffrey

The Kentucky Review

No abstract provided.

Library Notes: Selected Acquisitions [V. 13, No. 3], James D. Birchfield, Joseph R. Jones

The Kentucky Review

No abstract provided.

Fresh-Water Aquifer In The Knox Group (Cambrian–Ordovician) Of Central Kentucky, James A. Kipp

Report of Investigations--KGS

Fresh water can be found in Cambrian and Ordovician carbonate rocks of the Knox Group in central Kentucky. The top of the aquifer is as much as 300 ft above mean sea level (m.s.l.) on the crest of the Cincinnati Arch, but descends off the flanks of the arch. Water is normally found in the upper 100 to 250 ft of the Knox, primarily in secondary porosity apparently associated with the unconformity at the top of the unit. Knox wells commonly exceed 750 ft in total depth, but because the aquifer is artesian, water rises to an elevation of about …

Regulation Of The Internet: The Application Of Established Constitutional Law To Dangerous Electronic Communication, Adam R. Kegley

Kentucky Law Journal

No abstract provided.

Kentucky Traffic Accident Facts 1997 Report, Kentucky Transportation Center, Kentucky State Police

Kentucky Transportation Center Research Report

KENTUCKY’S TRAFFIC ACCIDENT FACTS report for 1997 is based on accident reports submitted to the Accident Unit housed in the Kentucky State Police Information Services Branch, Records Section. As required by Kentucky Revised statutes 189.635, “every law enforcement agency whose officers investigate a vehicle accident of which a report must be made...shall file a report of the accident...within ten days after investigation of the accident upon forms supplied by the bureau.” The stated purpose of this requirement is to utilize date on traffic accidents” for such purposes as will improve the traffic safety program in the Commonwealth.” Data contained in …

Runoff Quality Responses To Cattle-Gazing Strategy And Grassed Buffer Zone Length, Dwayne R. Edwards, Brian T. Larsen, Teng T. Lim

KWRRI Research Reports

Grazed pastures represent a source of potential nonpoint pollution. In comparison to other nonpoint sources (e.g., row-cropped lands), relatively little information exists regarding possible magnitudes of pollution from grazed pasture; how that pollution is affected by weather, soil, management and other variables; and how the pollution can be minimized. The objective of this study was to assess how the quality of runoff from simulated grazed pasture is influenced by grazing duration (4-12 weeks), grazing strategy (no grazing, conventional grazing and rotational grazing), and by the use of grassed buffer strips (ranging in length from O to 18.3 m) installed down-slope …

Vegetative Filter Strip Removal Of Metals In Runoff From Poultry Litter-Amended Fescuegrass Plots, Dwayne R. Edwards, P. A. Moore Jr., Tommy C. Daniel, Puneet Srivastava, D. J. Nichols

Biosystems and Agricultural Engineering Faculty Publications

Runoff from land areas amended with poultry (Gallus gallus domesticus) manure can contain elevated concentrations of metals such as Cu, Fe, and Zn. Vegetative filter strips (VFS) can reduce runoff concentrations of animal manure components, but reported studies have typically focused on nutrients and solids rather than metals. This experiment assessed the impact of VFS length (0 to 12 m) on concentrations and mass losses of Cu, Fe, K, Na, Ni, and Zn in runoff from fescuegrass (Festuca arundinacea Schreb.) plots (1.5 m wide × 6 and 12 m long) treated with poultry litter. The runoff was produced from simulated …

Solving The Insurance/Genetic Fair/Unfair Discrimination Dilemma In Light Of The Human Genome Project, Eric Mills Holmes

Kentucky Law Journal

No abstract provided.

Genetics, Genetic Testing, And The Specter Of Discrimination: A Discussion Using Hypothetical Cases, Richard H. Underwood, Ronald G. Cadle

Kentucky Law Journal

No abstract provided.

The Use Of Forensic Dna In Criminal Cases In Kentucky As Compared With Selected Other States, Judith E. Lewter

Kentucky Law Journal

No abstract provided.

Goodwin V. Turner: A Comparison Of American And Jewish Legal Perspectives On Procreation Rights Of Prisoners, Daniel Pollack, Chaim Steinmetz, Andrea Tellerman

Kentucky Law Journal

No abstract provided.

Method For Obtaining Antifungal And Herbicidal Compounds That Target The First Committed Step In Shingolipid Long-Chain Base Biosynthesis, Robert C. Dickson, Robert L. Lester

Molecular and Cellular Biochemistry Faculty Patents

The invention provides the LCB1 and LCB2 genes of the yeast Saccharomyces cerevisiae that encode subunits of the enzyme serine palmitoyltransferase (SPT), the first enzyme leading to synthesis of the long-base component of the sphingolipids. The present specification describes the isolation of the LCB1 and LCB2 genes. The invention further relates to methods of using these genes to either inhibit SPT activity or to inhibit synthesis of the enzyme. Furthermore, the invention relates to methods for constructing strains of S. cerevisiae or other organisms that can be used to select and to test for compounds that either inhibit SPT activity …

Evaluation Of A Regional Traffic Safety Improvement Program, Kenneth R. Agent

Kentucky Transportation Center Research Report

The objectives of this report were to document the activities and evaluate the effectiveness of a regional traffic safety improvement program in the Green River Area Development District (GRADD). This is a seven county region in western Kentucky. The goals of the program were to reduce the numbers of motor vehicle fatalities and injuries, to increase safety belt usage, and to increase public awareness of the effects of alcohol-related and high speed driving in rural areas.

A full-time employee was hired by GRADD to manage the program. A Citizen Advisory Board (CAB) was established in each county. Each CAB formulated …

Method And Compositions For Treating Age Related Disorders, John M. Carney, Robert A. Floyd

Pharmacology and Nutritional Sciences Faculty Patents

Compositions containing as the active ingredient a spin-trapping reagent, preferably α-phenyl butyl nitrone (PBN) or spin-trapping derivatives thereof, in a suitable pharmaceutical carrier for administration to a patient are disclosed for treating or preventing symptoms associated with aging or other conditions associated with oxidative tissue damage. Other spin-trapping agents can also be used, such as 5,5-dimethyl pyrroline N-oxide (DMPO) or α-(4-pyridyl 1-oxide)-N-tert-butylnitrone (POBN), and other spin-trapping derivatives thereof. These compositions and methods are useful in the treatment of age-related disorders, pre-surgical and/or pre-anesthetic preparation or administration of chemotherapeutic agents, and in the treatment of disorders or trauma of the brain, …

Don't Become Roadkill On The Information Superhighway: Dealing With Information Overload, Antoinette Paris Powell

Library Presentations

No abstract provided.

Cellular Basis Of Decreased Immune Responses To Pneumococcal Vaccines In Aged Mice, Manju Garg, Wei Luo, Alan M. Kaplan, Subbarao Bondada

Microbiology, Immunology, and Molecular Genetics Faculty Publications

Previously, model systems were developed in our laboratory to study murine immune responses to the 23-valent pneumococcal polysaccharide vaccine Pnu-Imune, both in vivo and in vitro (M. Garg and B. Subbarao, Infect. Immun. 60:2329-2336, 1992; M. Garg, A. M. Kaplan, and S. Bondada, J. Immunol. 152: 1589-1596, 1994). Using these systems, we found that aged mice did not respond to the vaccine in vivo or in vitro. Cell separation studies showed that the unresponsiveness of the aged spleen cells to the vaccine was not due to an intrinsic B-cell defect or to T-cell-mediated immunosuppression but resulted from an accessory cell …

Effect Of Sediment Particle Size And Temperature On Fecal Bacteria Mortality Rates And The Fecal Coliform/Fecal Streptococci Ratio, J. M. Howell, Mark S. Coyne, P. L. Cornelius

Plant and Soil Sciences Faculty Publications

Extended survival of fecal bacteria in sediment can obscure the source and extent of fecal contamination in agricultural settings. The variability in fecal coliform/fecal streptococci (FC/FS) ratios with time and discrepancies between observable fecal sources and measured FC/FS ratios in shallow surface water from agricultural watersheds may be explained by examining FC and FS mortality rates in response to ambient temperature and sediment particle size. We measured FC and FS mortality rates at three different temperatures and in three feces-amended sediments with different particle size in a laboratory study. In controlled conditions, using physiological saline to reduce cell death by …

Perjury: An Anthology, Richard H. Underwood

Law Faculty Scholarly Articles

Professor Underwood takes an in-depth look at the occurrence of perjury from ancient Rome to the O.J. Simpson trial. This journey through time provides insight into the motives of perjurers, the difficulties involved in catching them; and the alarming frequency with which they succeed, unchastised.

Use Of L-Canavanine As A Chemotherapeutic Agent For The Treatment Of Pancreatic Cancer, Peter Crooks, Gerald A. Rosenthal

Pharmaceutical Sciences Faculty Patents

A pharmaceutical composition of canavanine, and a method treatment of cancer, particularly pancreatic cancer with L-canavanine is disclosed.

The Protective Role Of Manganese Superoxide Dismutase Against Adriamycin-Induced Acute Cardiac Toxicity In Transgenic Mice, Hsiu-Chuan Yen, Terry D. Oberley, Satit Vichitbandha, Ye-Shih Ho, Daret K. St. Clair

Toxicology and Cancer Biology Faculty Publications

Adriamycin (ADR) is a potent anticancer drug known to cause severe cardiac toxicity. Although ADR generates free radicals, the role of free radicals in the development of cardiac toxicity and the intracellular target for ADR-induced cardiac toxicity are still not well understood. We produced three transgenic mice lines expressing increased levels of human manganese superoxide dismutase (MnSOD), a mitochondrial enzyme, as an animal model to investigate the role of ADR-mediated free radical generation in mitochondria. The human MnSOD was expressed, functionally active, and properly transported into mitochondria in the heart of transgenic mice. The levels of copper-zinc SOD, catalase, and …

Low Molecular Weight Thiocarbamates As Inhibitors Of Elastase, Uses And Method Of Synthesis, George Digenis, Nikolaos P. Rodis

Pharmaceutical Sciences Faculty Patents

To see this abstract, please download this patent.

Celluloid Death: Cinematic Depictions Of Capital Punishment, Roberta M. Harding

Law Faculty Scholarly Articles

This essay will examine how two filmmakers used the cinema to investigate death penalty issues through the films Dead Man Walking and Last Light. These films were selected because of their similarities: capital punishment is the central theme of both films; the presence of a strong principal character who is the condemned inmate; the utilization of a character who undergoes a spiritual transformation due to interaction with the condemned inmate; the decision to have this character facilitate the humanization of the condemned individual; and the additional role this character plays as the audiences' conscience. There are, however, differences in the …

Twig, Branch, And Stem Diseases Of Pine, John R. Hartman

Agriculture and Natural Resources Publications

Tip Blight

Tip blight, caused by the fungus Sphaeropsis sapinea (formerly Diplodia pinea), is a serious disease of mature Austrian, Scots (Scotch), and Mugo pines in Kentucky. In the landscape, tip blight is normally not observed until pines reach about 12 years old and begin to bear cones. Severe infections year after year can greatly weaken and eventually kill affected pines.

Development Of Accident Reduction Factors, Kenneth R. Agent, Nikiforos Stamatiadis, Samantha S. Jones

Kentucky Transportation Center Research Report

The objective of this project is to develop accident reduction factors associated with various types of highway safety improvements. These factors will be used in the cost-optimization procedure to rank safety improvements.

The basis of the accident reduction factors developed in this study is a survey of states and a review of literature. The recommended reduction factors are presented in a table which lists the percent reduction in all accidents or specific types of accidents for given types of improvements.

College Of Law Commencement Program, 1996, University Of Kentucky

Graduation Programs

No abstract provided.

Phenylbutyl Nitrone Compositions And Methods For Prevention Of Gastric Ulceration, John M. Carney, Robert A. Floyd

Pharmacology and Nutritional Sciences Faculty Patents

Compositions containing PBN, or active derivatives thereof, in a suitable pharmaceutical carrier for administration to a patient, are disclosed for treating or preventing gastric ulceration caused by ingestion of non-steroidal anti-inflammatories. Based on animal studies, the dosage is in the range of 3 to 300 mg/kg and is administered prior to, simultaneously, or shortly after ingestion of the NSAID compounds(s). In the preferred embodiment, the range is between 10 and 30 mg/kg, depending on the dosage unit required to protect the mucosa. The preferred method of administration is orally, alone or in combination with the non-steroidal anti-inflammatory. It is believed …

2,4-Disulfonyl Phenyl Butyl Nitrone, Its Salt And Their Use As Pharmaceuticals, John M. Carney

Pharmacology and Nutritional Sciences Faculty Patents

2,4-disulfonyl α-phenyl-tert-butyl nitrone and its pharmaceutically acceptable salts are disclosed. These materials are useful as pharmaceutical agents for oral or parenteral, e.g. intravenous administration to patients suffering from acute central nervous system oxidation as occurs in a stroke or from gradual central nervous system oxidation which can exhibit itself as progressive central nervous system function loss. The materials are also used to ameliorate the side effects of oxidative-damage causing antineoplastic disease treatments.