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Sandspur, Vol 117, No 22, March 24, 2011, Rollins College

The Rollins Sandspur

Rollins College student newspaper, written by the students and published at Rollins College. The Sandspur started as a literary journal.

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Lipophilic Polyamines Providing Enhanced Intracellular Delivery Of Agents By A Polyamine Transport System, Otto Phanstiel, Kenneth Teter

UCF Patents

All cells require polyamines in order to grow. Many cell types (including cancer cells) have active polyamine transporters which import extracellular polyamines into the cell. Our invention is the development of new lipophilic polyamines which can access cells via their polyamine transport system. The long lipid tails facilitate the formation of assembled complexes which are recognized and imported into cells. The invention describes several examples of using this technology for drug delivery and includes: a) the efficient delivery of foreign DNA into Chinese hamster ovary cells and expression of the protein encoded by the foreign DNA; and b) the delivery …

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Targeting Of Mkrni For Identifying Cancer Treatment Agents, Mark Muller, In Chung, Mi Kang, Jun Kim, Tae Lee, Sue Oh, Sun Park

UCF Patents

The molecular chaperone Hsp90 binds specifically to hTERT and is required for assembly of active telomerase activity. We show that disruption of Hsp90 function gy geldanamycin efficient ubiquitination and proteasome-mediated degradation of hTERT.

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Electrically Deflected Nanomechanical Sensors, Ming Su

UCF Patents

An electrically-induced deflective amplification sensor as an actively controlled and reconfigureable nanomechanical sensor for the detection and recognition of cehmicals, biomolecules, and gaseous molecules. The electrically-induced deflective amplification sensors use electric fields to control the bending of transducers, have adjustable sensitivites that depend on electric field strength, and reconfigureable operation ranges for the detection of target molecules at ultra-low and ultra-high concentrations. The sensors are highly integrated, sensitive, provide real-time detection ability, and do not require labels. The electrically-induced deflective amplification transducers can be reconfigured to identify molecules in spectroscopy. A new type of electrophoresis is established using nanostructured transducers. …

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Retention/Detention Pond And Green Roof Passive Nutrient Removal Material Mixes (Green Roof), Martin Wanielista, Ni-Bin Chang, Ammarin Makkeasorn

UCF Patents

Materials, compositions, substances, and methods and systems for stormwater treatment in wet ponds, dry ponds and a green roof system. A first embodiment provides in-situ treatment unit within the retention pond by withdrawing the stored stormwater tocirculate the stored stormewater into the in-situ treatment unit to sorb nitrogen from the stored stormwater. A second embodiment provided uses a riprap apron, a preforated riser loacted at the bottom of the riprap apron and a goetextile media encased in a sorption media jacket around the perforated riser. A third embodiment provides a greenroof stormwater treatment system that includes protections for waterproofing and …

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Sandspur, Vol 117, No 18, February 17, 2011, Rollins College

The Rollins Sandspur

Rollins College student newspaper, written by the students and published at Rollins College. The Sandspur started as a literary journal.

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Tissue Substitutes Comprising Stem Cells And Reduced Ceria, Kiminobu Sugaya, Petya Georgieva, Stephanie Merchant, Sudipta Seal, Manny Vrotsos

UCF Patents

A biocompatible composite includes a solid biocompatible material and stem cells attached thereto. The biocomposite provides a stable interface with endogenous tissue and the implanted composition resulting in accelerated repair to damaged bones and tissues. A method of repairing bone includes the steps of obtaining live stem cells from a patient to be treated or a haplotype matched donor and culturing the stem cells with a biocompatible material. The stem cells attach to a surface of the biocompatible material to form a biocompatible composite. The biocompatible composite is positioned in proximity to bone to be treated, wherein said stem cell …

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Sandspur, Vol 117, No 14, January 21, 2011, Rollins College

The Rollins Sandspur

Rollins College student newspaper, written by the students and published at Rollins College. The Sandspur started as a literary journal.

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Novel Copper Loaded Core-Shell Silica Nanoparticles With Improved Copper Bioavailability Synthesis, Characterization And Study Of Antibacterial Properties, Pavithra Maniprasad

Electronic Theses and Dissertations

A novel core-shell silica based antimicrobial nanoparticle was synthesized. The Stöber silica shell has been engineered to accommodate copper. Synthesis of the core-shell Cu-silica nanoparticle (C-S CuSiNP) involves preparation of base-hydrolyzed Stöber silica “seed” particles first, followed by the acid-catalyzed seeded growth of the Cu-silica shell layer around the core. Scanning electron microscopy and transmission electron microscopy showed monodispersed, spherical shaped nanoparticles with smooth surface morphology. Characterization of particle size distribution in solution by the Dynamic Light Scattering (DLS) technique was fairly consistent with the electron microscopy results. Loading of Cu to nanoparticles was confirmed by the SEM-Energy Dispersive X-Ray …

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A Solid Phase Assay For Topoisomerase I Interfacial Poisons And Catalytic Inhibitors, Vidusha Cyril

Electronic Theses and Dissertations

We report a mechanism based screening technique to rapidly identify eukaryotic topoisomerase I targeting agents. The method is based on genetic tagging of topoisomerase I to immobilize the enzyme on a solid surface in a microtiter well format. DNA is added to the wells and retained DNA is detected by Picogreen fluorescence. Compounds that result in an increase in Picogreen staining represent potential topoisomerase interfacial poisons while those that reduce fluorescence report catalytic inhibitors; therefore, the solid phase assay represents a „bimodal‟ readout that reveals mechanisms of action. The method has been demonstrated to work with known interfacial poisons and …

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Organizational Support, Organizational Citizenship Behavior, And Perceived Performance Analysis Of Crime Scene Investigation Units Of Turkish National Police, Aykut Tongur

Electronic Theses and Dissertations

Policing is more difficult than ever before in today’s world since types of crime and criminal profiles change as a result of technological development and globalization. Police organizations should review their organizational and operational strategies to improve the fight against contemporary crimes and criminals. Behaviors and performance of police officers are very important in fighting crime. In this struggle, especially today, officers should exhibit organizational citizenship behaviors and perform better. One of the most important factors affecting these two concepts in organizations is organizational support. The literature stresses the social exchange cycle and reciprocity rules in the relationships of organizations …

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Identification Of Factors Influencing The Commission Of Burglaries, Mustafa Donmez

Electronic Theses and Dissertations

As in many countries, burglary is a very serious crime in Turkey. Scientific methods and techniques are needed to solve complex burglary cases. This study is completed in the Bursa Police context since they classified many crime data conducive to scientific studies under a project called BEMTAP. The main purpose of this study is to examine the factors influencing the commission of burglaries, using an epid-criminological perspective. It can be argued that factors leading to the commission of a crime are important for formulating preventive strategies in the community. In this study, the contributing factors are categorized into three main …

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University Of Central Florida Factbook 2010-2011, University Of Central Florida

Historical Fact Book and Enrollment

Historical fact book and enrollment data for the University of Central Florida.

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The Learning Marketspace, January 2011, Bob Heterick, Carol Twigg

The Learning MarketSpace (4/03 - 4/14)

No abstract provided.

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An Evaluation Study Of The Effectiveness Of Using A Reaction-Based Process For Hydrazine Waste Remediation, Cristina M. Oropeza

Electronic Theses and Dissertations

Hydrazine (HZ) and monomethylhydrazine (MMH) are used extensively as hypergolic propellants at Kennedy Space Center. These highly reactive fuels are considered highly toxic, and potentially carcinogenic. Consequently, the transport, handling, and disposal of hydrazines is strictly regulated to protect personnel and the environment. Currently, KSC generates large volumes of hydrazine-laden wastewater for disposal. This waste is contained and shipped on public highways for subsequent disposal by incineration presenting a potentially catastrophic threat to the environment and the general public in the event of an accidental release. Other existing remediation methods include oxidative and reductive pathways as well as biodegradation in …

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Gore's Science The Kairos Of An Inconvenient Truth And The Implications For Science Writing, Carolyn M. Glasshoff

Electronic Theses and Dissertations

Modern Americans are exposed to scientific and technical information on a daily basis that urges them to react as well as learn about new ideas. The popular science writing that circulates this information must be portrayed in a way that makes it easy for lay people to understand complicated ideas while at the same time remaining complex enough to convince readers that the information is reliable, accurate, and worth learning. In making decisions about how to accomplish this balancing act, science writers make decisions that influence the audience's opinion about new scientific ideas, how easily the audience will accept or …

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The Sheddase Activity Of Adam10/Adam17 On Cxcl16 Increases Proliferation And Survival Of Colorectal Cancer Cells, Tamu C. Talton

Electronic Theses and Dissertations

CXCL16 is an interferon-inducible chemokine of the CXC-subfamily and functions as an adhesion molecule, when membrane bound, and a chemoattractant when soluble. Upregulation of cell associated CXCL16 (cCXCL16) in colorectal cancer is associated with increased tumor infiltrating lymphocytes and good prognosis. ADAM10 and ADAM17 are metalloproteinases responsible for cleaving CXCL16, releasing soluble CXCL16 (sCXCL16) and contributing to proliferation and migration of mesangial cells, in kidney inflammatory disease. We hypothesize that cCXCL16 is a substrate for ADAM10 and ADAM17 cleavage in colorectal cancer, releasing sCXCL16, which mediates cell proliferation. To this end, we first identified CXCL16 in the human colon carcinoma …

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An Ecological Analysis Of Social And Economic Influences On Black And White Infant Mortality Risk In Orange County, Fl, Littleton, Vanessa Lopez

Electronic Theses and Dissertations

Black health disparities are a salient public health issue with blacks in every socioeconomic level at a greater health disadvantage than their white counterparts. In particular, disparity in infant mortality rates between blacks and whites have widened in recent decades to differentials never before experienced in the United States. Social ecologists investigating the myriad of individual and environmental risk factors have failed to fully account for the persistent differential. This study examines the relationships between individual and environmental influences on the health risk experienced by blacks, whites, as well as the differential between the two populations. This multi-level analysis was …

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Harmony Oriented Architecture, Kyle A. Martin

Electronic Theses and Dissertations

This thesis presents Harmony Oriented Architecture: a novel architectural paradigm that applies the principles of Harmony Oriented Programming to the architecture of scalable and evolvable distributed systems. It is motivated by research on Ultra Large Scale systems that has revealed inherent limitations in human ability to design large-scale software systems that can only be overcome through radical alternatives to traditional object-oriented software engineering practice that simplifies the construction of highly scalable and evolvable system. HOP eschews encapsulation and information hiding, the core principles of objectoriented design, in favor of exposure and information sharing through a spatial abstraction. This helps to …

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Density Functional Theory Study Of Molecules And Crystals Containing D And F Metals, Shruba Gangopadhyay

Electronic Theses and Dissertations

Density Functional Theory (DFT) method is applied to study the crystal structure of transition metal and lanthanide oxides, as well as molecular magnetic complexes. DFT is a widely popular computational approach because it recasts a many-body problem of interacting electrons into an equivalent problem of non-interacting electrons, greatly reducing computational cost. We show that for certain structural properties like phase stability, lattice parameter and oxygen migration energetics pure DFT can give good agreement with experiments. But moving to more sensitive properties like spin state energetic certain modifications of standard DFT are needed. First we investigated mixed ionic-electronic conducting perovskite type …

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Adaptive Responses Of Branchial Morphology To Hypoxia In The Neotropical Electric Fish Genus Brachyhypopomus, Leilani B. Pathak

Electronic Theses and Dissertations

Many tropical aquatic environments worldwide are characterized by intermittent or prolonged hypoxia (low dissolved oxygen). Nevertheless, many tropical freshwater fishes are able to inhabit these challenging environments via a range of morphological, physiological and behavioral adaptations. Brachyhypopomus is a diverse genus of weakly electric fishes represented by 28 known species distributed from Panama to Argentina. 17 species are restricted to permanently normoxic habitats (blackwater rivers and terra firme streams), eight species are restricted to seasonally or perennially hypoxic habitats (whitewater floodplains of large tropical rivers or permanent swampy habitats), and three species are eurytopic (occur in both seasonally hypoxic and …

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Virtualization And Self-Organization For Utility Computing, Mehdi Saleh

Electronic Theses and Dissertations

We present an alternative paradigm for utility computing when the delivery of service is subject to binding contracts; the solution we propose is based on resource virtualization and a selfmanagement scheme. A virtual cloud aggregates set virtual machines to work in concert for the tasks specified by the service agreement. A first step for the establishment of a virtual cloud is to create a scale-free overlay network through a biased random walk; scale-free networks enjoy a set of remarkable properties such as: robustness against random failures, favorable scaling, and resilience to congestion, small diameter, and average path length. Constrains such …

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The Performance And Power Impact Of Using Multiple Dram Address Mapping Schemes In Multicore Processors, Rami Jadaa

Electronic Theses and Dissertations

Lowest-level cache misses are satisfied by the main memory through a specific address mapping scheme that is hard-coded in the memory controller. A dynamic address mapping scheme technique is investigated to provide higher performance and lower power consumption, and a method to throttle memory to meet a specific power budget. Several experiments are conducted on single and multithreaded synthetic memory traces -to study extreme cases- and validate the usability of the proposed dynamic mapping scheme over the fixed one. Results show that applications’ performance varies according to the mapping scheme used, and a dynamic mapping scheme achieves up to 2x …

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Mechanisms Of Alpha]-Synuclein-Induced Neurodegenertaion In Parkinson's Disease And Stroke, Cherine Belal

Electronic Theses and Dissertations

Parkinson’s disease (PD) is a debilitating neurodegenerative disorder affecting one million Americans. Despite its social and economic impact, the pathological cascades that lead to neuron dysfunction and degeneration in PD are poorly understood. Endoplasmic reticulum (ER) stress has been implicated as an initiator or contributing factor in neurodegenerative diseases including PD. The ER is an organelle central to protein folding and intracellular Ca2+ homeostasis. Perturbations of these functions result in ER stress and upregulation of ER stress proteins, of which some have been implicated in counteracting ER stress-induced cell death. The mechanisms that lead to ER stress and how ER …

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Identification Of Fabrics Likely To Collect And Disperse Fel D 1, Mary Janice Jones

Electronic Theses and Dissertations

Individuals sensitive to domestic cat allergen Fel d 1 experience a variety of symptoms including eye irritation, respiratory irritation, asthma, and severe respiratory distress. Fel d 1 is a protein produced in the saliva and on the skin of domestic cats. Previous studies have demonstrated that Fel d 1 adheres to clothing, upholstery, and human hair and has been found in non-cat environments in levels high enough to cause allergic reactions in sensitive individuals. In a general sense, two very different approaches have been adopted to study Fel d 1. One area of the literature focuses on the molecular biology …

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Photodisruption In Ocular Tissue Near And At The Boundary Between The Anterior Chamber And Crystalline Lens, Richard Ty Olmstead

Electronic Theses and Dissertations

Lasers have been involved in Ophthalmology in the treatment of myopia and hyperopia for several years. Laser systems have transformed patients‟ quality of life, freeing them from the need for glasses, as in the case of LASIK. Ultrafast lasers have played an important role in surgery of the eye. In LASIK, they are used to cut the flap that is lifted to expose the stroma for UV Excimer laser treatment of this region. They are now being used for surgery deeper into the eye,for instance, treating the lens as part of treatments for cataract surgery. The use of ultrafast lasers …

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Communication Apprehension Vs. Social Phobia And Related Conditions A Correlational Study, Christine M. Donaldson

Electronic Theses and Dissertations

Of all social situations, public speaking is the most prevalent fear in both the general population and among social phobic individuals (Mannuzza, Schneier, Chapman, & Liebowitz, 1995; Stein, Walker, & Forde, 1996). The fear of public speaking is referred to as communication apprehension (CA) by members of the communication field; in other programs of study, this condition has been categorized and conceptualized in a wide variety of ways ranging from stage fright to reticence. Several scholarly fields including communication, social psychology, the health sciences and the social sciences, seek to find an explanation and effective intervention for this prevalent condition. …

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Factors Related To Birth Transition Success Of Late-Preterm Infants, Karen L. Wright

Electronic Theses and Dissertations

Problem: Identifying the factors effecting birth transition success of late preterm infants may improve early recognition of newborn compromise. Multiple explanatory variables may be associated with birth transition success or failure. The purpose of the study was to determine the prevalence of, and clinical-epidemiological and demographic predictive factors for birth transition success of late preterm infants. Methods: A retrospective case-control chart review was used to compare the characteristics of successful and unsuccessful birth transition of 35 and 36 week gestational age late-preterm infants delivered in a large tertiary-care center during calendar year 2007. A mixture of categorical and numeric variables …

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Multiagent Learning Through Indirect Encoding, David B. D'Ambrosio

Electronic Theses and Dissertations

Designing a system of multiple, heterogeneous agents that cooperate to achieve a common goal is a difficult task, but it is also a common real-world problem. Multiagent learning addresses this problem by training the team to cooperate through a learning algorithm. However, most traditional approaches treat multiagent learning as a combination of multiple single-agent learning problems. This perspective leads to many inefficiencies in learning such as the problem of reinvention, whereby fundamental skills and policies that all agents should possess must be rediscovered independently for each team member. For example, in soccer, all the players know how to pass and …

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Use Of Vegetative Mulch As Daily And Intermediate Landfill Cover, Assal Edwar Haddad

Electronic Theses and Dissertations

Management of yard waste is a significant challenge in the US, where in 2008 13.2% of the 250 million tons of municipal solid waste (MSW) was reported to be yard waste. This study describes research conducted in the laboratory and field to examine the application of vegetative mulch as daily and intermediate landfill cover. Mulch was found to exhibit stronger physical properties than soil, leading to a more stable landfill slope. Compaction of mulch was found to be significantly greater than soil, potentially resulting in airspace recovery. Degradation of mulch produced a soil-like material; degradation resulted in lower physical strength …

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Full-Text Articles in Entire DC Network

Sandspur, Vol 117, No 22, March 24, 2011, Rollins College

The Rollins Sandspur

Lipophilic Polyamines Providing Enhanced Intracellular Delivery Of Agents By A Polyamine Transport System, Otto Phanstiel, Kenneth Teter

UCF Patents

Targeting Of Mkrni For Identifying Cancer Treatment Agents, Mark Muller, In Chung, Mi Kang, Jun Kim, Tae Lee, Sue Oh, Sun Park

UCF Patents

Electrically Deflected Nanomechanical Sensors, Ming Su

UCF Patents

Retention/Detention Pond And Green Roof Passive Nutrient Removal Material Mixes (Green Roof), Martin Wanielista, Ni-Bin Chang, Ammarin Makkeasorn

UCF Patents

Sandspur, Vol 117, No 18, February 17, 2011, Rollins College

The Rollins Sandspur

Tissue Substitutes Comprising Stem Cells And Reduced Ceria, Kiminobu Sugaya, Petya Georgieva, Stephanie Merchant, Sudipta Seal, Manny Vrotsos

UCF Patents

Sandspur, Vol 117, No 14, January 21, 2011, Rollins College

The Rollins Sandspur

Novel Copper Loaded Core-Shell Silica Nanoparticles With Improved Copper Bioavailability Synthesis, Characterization And Study Of Antibacterial Properties, Pavithra Maniprasad

Electronic Theses and Dissertations

A Solid Phase Assay For Topoisomerase I Interfacial Poisons And Catalytic Inhibitors, Vidusha Cyril

Electronic Theses and Dissertations

Organizational Support, Organizational Citizenship Behavior, And Perceived Performance Analysis Of Crime Scene Investigation Units Of Turkish National Police, Aykut Tongur

Electronic Theses and Dissertations

Identification Of Factors Influencing The Commission Of Burglaries, Mustafa Donmez

Electronic Theses and Dissertations

University Of Central Florida Factbook 2010-2011, University Of Central Florida

Historical Fact Book and Enrollment

The Learning Marketspace, January 2011, Bob Heterick, Carol Twigg

The Learning MarketSpace (4/03 - 4/14)

An Evaluation Study Of The Effectiveness Of Using A Reaction-Based Process For Hydrazine Waste Remediation, Cristina M. Oropeza

Electronic Theses and Dissertations

Gore's Science The Kairos Of An Inconvenient Truth And The Implications For Science Writing, Carolyn M. Glasshoff

Electronic Theses and Dissertations

The Sheddase Activity Of Adam10/Adam17 On Cxcl16 Increases Proliferation And Survival Of Colorectal Cancer Cells, Tamu C. Talton

Electronic Theses and Dissertations

An Ecological Analysis Of Social And Economic Influences On Black And White Infant Mortality Risk In Orange County, Fl, Littleton, Vanessa Lopez

Electronic Theses and Dissertations

Harmony Oriented Architecture, Kyle A. Martin

Electronic Theses and Dissertations

Density Functional Theory Study Of Molecules And Crystals Containing D And F Metals, Shruba Gangopadhyay

Electronic Theses and Dissertations

Adaptive Responses Of Branchial Morphology To Hypoxia In The Neotropical Electric Fish Genus Brachyhypopomus, Leilani B. Pathak

Electronic Theses and Dissertations

Virtualization And Self-Organization For Utility Computing, Mehdi Saleh

Electronic Theses and Dissertations

The Performance And Power Impact Of Using Multiple Dram Address Mapping Schemes In Multicore Processors, Rami Jadaa

Electronic Theses and Dissertations

Mechanisms Of Alpha]-Synuclein-Induced Neurodegenertaion In Parkinson's Disease And Stroke, Cherine Belal

Electronic Theses and Dissertations

Identification Of Fabrics Likely To Collect And Disperse Fel D 1, Mary Janice Jones

Electronic Theses and Dissertations

Photodisruption In Ocular Tissue Near And At The Boundary Between The Anterior Chamber And Crystalline Lens, Richard Ty Olmstead

Electronic Theses and Dissertations

Communication Apprehension Vs. Social Phobia And Related Conditions A Correlational Study, Christine M. Donaldson

Electronic Theses and Dissertations

Factors Related To Birth Transition Success Of Late-Preterm Infants, Karen L. Wright

Electronic Theses and Dissertations

Multiagent Learning Through Indirect Encoding, David B. D'Ambrosio

Electronic Theses and Dissertations

Use Of Vegetative Mulch As Daily And Intermediate Landfill Cover, Assal Edwar Haddad

Electronic Theses and Dissertations