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The Family Medical Leave Act: The Current Regulations And Future Recommended Changes, Olivia Schmidt May 2023

The Family Medical Leave Act: The Current Regulations And Future Recommended Changes, Olivia Schmidt

Management Undergraduate Honors Theses

The Family Medical Leave Act was implemented in 1993, affecting thousands of employees. This act allows caregivers the time to care for their loved ones and for people to take the time they need to heal and care for themselves, all while maintaining their careers. While the workforce and it’s needs have changed over the years, FMLA has remained stagnant with minimal adjustments at the federal level. There are many different aspects to FMLA including different state regulations, different industry effects, and the special case of the airline industry. While FMLA was an important change in 1993, it needs to …

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In-Service Education And The Provision Of Educational Materials To Improve Awareness Of Chronic Wasting Disease Management Efforts In Arkansas, Mary Claire Stewart May 2023

In-Service Education And The Provision Of Educational Materials To Improve Awareness Of Chronic Wasting Disease Management Efforts In Arkansas, Mary Claire Stewart

Animal Science Undergraduate Honors Theses

Chronic Wasting Disease (CWD) is a disease caused by an accumulation of misfolded prions throughout the nervous system. This disease affects animals within the Cervidae Family, which includes deer, elk, moose, and caribou. This disease is fatal and physical symptoms often do not materialize until the animal is near death. CWD has become an increasing issue in Arkansas since an elk (Cervus canadensis) in Newton County tested positive for CWD in 2016. Since then, the Arkansas Game and Fish Commission (AGFC) has worked with the University of Arkansas Division of Agriculture (UADA) and others to develop management strategies to slow …

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Personal Equation, Nicholas Hobbs May 2023

Personal Equation, Nicholas Hobbs

Graduate Theses and Dissertations

The body of this paper is a formatted version of text which exists natively on the web and is accessible at www.personalequation.art. Its non-linear narrative is meant to accompany and mirror, not describe, the artwork in the exhibition. The following two paragraphs are copied from the exhibition statement accompanying Personal Equation, which is on view in the Reading Room at the Fayetteville Public Library from April 3 to June 30, 2023: A personal equation is one that attempts to account for the inevitable role of subjectivity in scientific observations. The term was coined by astronomers in the 18th century who, …

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Evaluation Of Hydrogeochemical Characteristics Of San Joaquin, Tulare, And Mojave Aquifers, Southern California, Maedeh Hassanvand May 2023

Evaluation Of Hydrogeochemical Characteristics Of San Joaquin, Tulare, And Mojave Aquifers, Southern California, Maedeh Hassanvand

Graduate Theses and Dissertations

Before making attempts to enhance and manage the quality of water, a thorough understanding of these processes is necessary since the chemical quality of groundwater is impacted by a number of linked processes. This would be more important in arid and semiarid regions like the southern part of California where more rely on groundwater for agriculture and drinking water uses than the other states. As a result, fundamental knowledge of the governing processes of groundwater chemistry is required for effective water resource management. Thus, this study is primarily concerned with three aspects in Mojave, Tulare, and San Joaquin aquifers: The …

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Modeling And Control Strategies For A Two-Wheel Balancing Mobile Robot, John Alan Moritz May 2023

Modeling And Control Strategies For A Two-Wheel Balancing Mobile Robot, John Alan Moritz

Graduate Theses and Dissertations

The problem of balancing and autonomously navigating a two-wheel mobile robot is an increasingly active area of research, due to its potential applications in last-mile delivery, pedestrian transportation, warehouse automation, parts supply, agriculture, surveillance, and monitoring. This thesis investigates the design and control of a two-wheel balancing mobile robot using three different control strategies: Proportional Integral Derivative (PID) controllers, Sliding Mode Control, and Deep Q-Learning methodology. The mobile robot is modeled using a dynamic and kinematic model, and its motion is simulated in a custom MATLAB/Simulink environment. The first part of the thesis focuses on developing a dynamic and kinematic …

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Evaluation Of Rice Stink Bug, Oebalus Pugnax (F.), Resistance To Lambda-Cyhalothrin And The Economic Impact On Rice Grain Quality For Multiple Foliar Insecticides, Trevor Bradley Newkirk May 2023

Evaluation Of Rice Stink Bug, Oebalus Pugnax (F.), Resistance To Lambda-Cyhalothrin And The Economic Impact On Rice Grain Quality For Multiple Foliar Insecticides, Trevor Bradley Newkirk

Graduate Theses and Dissertations

Rice stink bug, (RSB), Oebalus pugnax (F.), (Fabricius 1775) is the major pest of headed rice, Oryza sativa L. in the southern rice producing states. The evaluation of current insecticides is imperative to efficient and economical RSB management for rice growers. Multiple reports of field failures with lambda-cyhalothrin have been documented since 2019. Lambda-cyhalothrin has been the standard for RSB control for the past two decades. The objective for this research was to determine if RSB is becoming resistant to lambda-cyhalothrin in Arkansas, and the most economical insecticide choice for growers with respect to RSB control and grain quality. RSB …

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Evaluation Of Thresholds, Control, And Behavioral Responses Of Tobacco Thrips, Frankliniella Fusca (Hitch), And Tarnished Plant Bugs, Lygus Lineolaris (Beauvoris), In Thryvon Cotton, Adam Young Whitfield May 2023

Evaluation Of Thresholds, Control, And Behavioral Responses Of Tobacco Thrips, Frankliniella Fusca (Hitch), And Tarnished Plant Bugs, Lygus Lineolaris (Beauvoris), In Thryvon Cotton, Adam Young Whitfield

Graduate Theses and Dissertations

Tobacco thrips are an important pest in Mid-South cotton production. Thrips are a pest of seedling cotton, feeding on the leaf tissue of plants which can result in stunted growth, delayed fruiting, loss of apical dominance, and possible stand loss. Field studies were conducted in 2021 and 2022 to evaluate Thryvon, a new transgenic trait in cotton that produces the Bt toxin Cry51Aa, for control of tobacco thrips. Thryvon cotton was tested at three locations in Arkansas: Marianna, Tillar, and Keiser. These studies evaluated thrips control on ThryvOn vs non-ThryvOn cotton and the effect of insecticide seed treatments on ThryvOn …

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Geophysical Assessment Of Internal Erosion Damage At The Crawford County Levee, Samuel Ross Hokett May 2023

Geophysical Assessment Of Internal Erosion Damage At The Crawford County Levee, Samuel Ross Hokett

Graduate Theses and Dissertations

Levee failures during flooding events can result in catastrophic loss of life and property. Soil erosion during high water events is a primary cause of levee failures. Accordingly, this research focuses on the geophysical assessment of internal erosion damage in levees. This thesis presents a case study utilizing Capacitively Coupled Resistivity (CCR), Direct Current Electrical Resistivity Tomography (DC ERT), and Multichannel Analysis of Surface Waves (MASW) to assess internal erosion damage at the Crawford County Levee System in Van Buren, AR, that occurred during the 2019 Arkansas River flood. Geophysical surveys acquired included longitudinal CCR, DC ERT, and MASW lines …

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Evaluation Of Bt Cotton Cultivar Efficacy And Economic Impact On Cotton Yield With And Without A Foliar Insecticide Application, Zackary Murray May 2023

Evaluation Of Bt Cotton Cultivar Efficacy And Economic Impact On Cotton Yield With And Without A Foliar Insecticide Application, Zackary Murray

Graduate Theses and Dissertations

Helicoverpa zea is the second most damaging insect pest of cotton in Arkansas. It is becoming more difficult to control in the United States due to recently documented resistant to dual gene cultivars. The objective of this thesis was to develop a better understanding of the efficacy of several Bt cotton technologies and foliar insecticides used to manage H. zea. Experiments examined damage in current commercial non-Bt, dual gene, and three gene cotton cultivars. Other experiments evaluated if H. zea could detect concentrations of chlorantraniliprole and residual of chlorantraniliprole in cotton for an extended period after application. These studies suggest …

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Correlation Of Intracellular Metabolites With Optical Metabolic Imaging In Polarized Macrophages As Indicators Of Metabolic Reprogramming, Abby Claire Denison, Shelby Bess May 2023

Correlation Of Intracellular Metabolites With Optical Metabolic Imaging In Polarized Macrophages As Indicators Of Metabolic Reprogramming, Abby Claire Denison, Shelby Bess

Biomedical Engineering Undergraduate Honors Theses

Macrophages are a type of immune cell that are characterized by their ability to differentiate into various active phenotypes based on environmental stimuli. They can generally be classified as one of two extremes: inflammatory/M1 or wound-healing/M2. Macrophage populations in vivo, however, are rarely homogenous, and since macrophages play vital roles in the immune response, particularly in the context of the tumor microenvironment (TME), it’s important to be able to investigate and understand heterogenous macrophage populations to develop more effective treatments. Recently, autofluorescence imaging such as multiphoton microscopy and fluorescence lifetime imaging microscopy (FLIM) of metabolic cofactors NADH and FAD have …

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Automated Visualization Pipeline For Near Real-Time Risk Management System, Paris Joslin May 2023

Automated Visualization Pipeline For Near Real-Time Risk Management System, Paris Joslin

Industrial Engineering Undergraduate Honors Theses

In modern society, technological capabilities and the amount of data readily available to users continue to grow exponentially. Many have adopted these new capabilities but lack the infrastructure needed to efficiently utilize high-powered software and programs. Without a method to collect, store, and process large datasets in real-time, individuals and businesses can quickly become overwhelmed, inhibiting effective decision-making processes. There is potential to improve decision-making abilities by enhancing the computing infrastructure. To accomplish this task, we will explore the ideas surrounding High Performance Computing (HPC) and data visualization software. High Performance Computing is the ability to process data and perform …

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Adolescents With Family History Of Alcohol-Use Disorders Have Reduced Structural Coherence Of Anterior Insula To Nucleus Accumbens Tract, Grace Wood May 2023

Adolescents With Family History Of Alcohol-Use Disorders Have Reduced Structural Coherence Of Anterior Insula To Nucleus Accumbens Tract, Grace Wood

Psychological Science Undergraduate Honors Theses

Genetics play a significant role in predisposition towards alcohol use disorders. Analyzing the neural phenotypes related to alcohol use disorder development could allow researchers to predict one’s predisposition. The anterior insula (AIns) contributes to binge drinking tendencies while exhibiting downstream signaling towards the nucleus accumbens (NAcc). Recent research has examined this relationship simultaneously with alcohol consumption, but the genetic effect of the AIns and NAcc functional relationship prior to alcohol consumption has yet to be examined. In this study, we used data from the Adolescent Brain Cognitive Development (ABCD) study to analyze the structural coherence of the AIns to NAcc …

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The Connections Among Worry, Sleep Hygiene, And Sleep Quality, Anna Quesada May 2023

The Connections Among Worry, Sleep Hygiene, And Sleep Quality, Anna Quesada

Psychological Science Undergraduate Honors Theses

Sleep disturbances commonly plague undergraduate students (Buboltz et al., 2001). In fact, being an undergraduate student is a risk factor for developing a sleep disturbance (Medic et. al., 2017). Understanding the impact of worry on the relationship between sleep hygiene and sleep disturbances could inform strategies for improving sleep quality in undergraduate populations. Given the fact that sleep issues affect health and academic performance negatively (Buboltz, et al., 2001), improving sleep patterns may boost academic performance, physical health, and mental health. This study investigated relationships between sleep hygiene and worry in an undergraduate sample by using a longitudinal design. Participants …

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Examining Fear Of Negative Evaluation In Oral Contraceptive Users And Naturally Cycling Women, Emily Furlow May 2023

Examining Fear Of Negative Evaluation In Oral Contraceptive Users And Naturally Cycling Women, Emily Furlow

Psychological Science Undergraduate Honors Theses

Oral contraceptive use has gained popularity over recent decades and is currently the most used form of contraception. However, women who take oral contraceptives may experience significant side effects that impact their bodies, moods, and emotions. The current study examined fear of negative evaluation in women taking oral contraceptives and women who were naturally cycling following a social stress test. I hypothesized oral contraceptive users would have a higher fear of negative evaluation in comparison to naturally cycling women following the Trier Social Stress Test. Results did not support this hypothesis. There was marginal support for the opposite effect. Following …

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The Effects Of Salt And Temperature On Three Methanogen Species: Implications For Mars, Katy Dunlap May 2023

The Effects Of Salt And Temperature On Three Methanogen Species: Implications For Mars, Katy Dunlap

Biological Sciences Undergraduate Honors Theses

The question of whether life has ever existed on Mars – either in the past or currently – has been pursued for decades. This debate has been prompted by a variety of discoveries regarding similarities between Mars and Earth and more recently concerns over human extinction. Mars, like Earth, once had large amounts of water, a key ingredient for life. H2O exists on Mars in various forms now, and it is theorized that there is liquid water beneath the surface as well. Mars also contains salt and is very cold at its surface, pointing researchers towards the idea …

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Investigating The Role Of The Sumo-Activating Enzyme, Uba2, In Infection-Related Morphogenesis Of Magnaporthe Oryzae, Rachel Taylor May 2023

Investigating The Role Of The Sumo-Activating Enzyme, Uba2, In Infection-Related Morphogenesis Of Magnaporthe Oryzae, Rachel Taylor

Biological Sciences Undergraduate Honors Theses

The plant pathogenic fungus Magnaporthe oryzae forms a specialized pressure-generating infection cell called an appressorium on the leaf surface, which it uses to mechanically rupture the otherwise impenetrable cuticle, enabling colonization of the underlying tissue and the establishment of blast disease. Appressorium differentiation by M. oryzae is cell cycle-regulated and requires programmed cell death of a three-celled propagative spore, as well as extensive remodeling of the microtubule, actin, and septin cytoskeletons. Recent studies have proposed the importance of sumoylation – the enzymatic conjugation of a small ubiquitin-like modifier to target proteins, for various aspects of infection-related development by M. oryzae, …

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An Overview Of Serial Depletions Of Global Marine Fisheries 1950 To 2019, Alison Follmer May 2023

An Overview Of Serial Depletions Of Global Marine Fisheries 1950 To 2019, Alison Follmer

Biological Sciences Undergraduate Honors Theses

Overfishing is a global issue that poses a significant risk to the entire ocean ecosystem in diminishing biodiversity and ecosystem function. This thesis examined the pattern and pace of fisheries depletions due to commercial fishing during the past 70 years. The Food and Agriculture Organization of the United Nations (FAO) Division of Fisheries and Aquaculture maintains a database of global hauls of marine taxa (reported in metric tonnes) from 1950 – 2019. These data were queried to determine the total number and sequence of fisheries depletions documented by the historic record. Analysis of this database showed progressive, linearly-increasing exploitation of …

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Optimum Time To Add The Feed Additive Availa-Zmc To Reduce The Incidence Of Bacterial Chondronecrosis With Osteomyelitis Lameness In Broiler Chickens, Ashley Ault May 2023

Optimum Time To Add The Feed Additive Availa-Zmc To Reduce The Incidence Of Bacterial Chondronecrosis With Osteomyelitis Lameness In Broiler Chickens, Ashley Ault

Biological Sciences Undergraduate Honors Theses

Lameness is a health condition threatening the welfare of broiler chickens in the poultry industry. It can be caused by a bacterial infection called Bacterial Chondronecrosis with Osteomyelitis (BCO). Zinpro has created Avalia-ZMC, a feed additive that has been proven to reduce lameness by 20% in wire-flooring pens and 25% in litter-flooring pens (Alrubaye et al., 2020). This experiment focuses on the optimal time to add Availa-ZMC to the diet of the broiler chickens to help reduce the incidence of lameness. This trial took 56 days with 26 pens at the University of Arkansas Poultry Research Farm. At the start …

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Measuring Energy Demands Of Dynamic Remodeling Events During Embryogenesis In Live Drosophila Embryos, Grayson Young May 2023

Measuring Energy Demands Of Dynamic Remodeling Events During Embryogenesis In Live Drosophila Embryos, Grayson Young

Biological Sciences Undergraduate Honors Theses

Embryonic development is a complex process requiring dynamic cell movements to create complex tissue structures. We assume that these embryonic dynamic remodeling events are highly energy intensive and that this energy expenditure is mediated by mitochondria. However, this has been difficult to demonstrate in live embryos. Convergent extension of the Drosophila neuroectoderm is a promising system to study the bioenergetics of tissue remodeling because it changes from a static to a dynamically remodeling tissue with temporal precision. We hypothesize that the switch from static to dynamic development at the onset of convergent extension will be accompanied by an increase in …

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Effects Of Sow Vocalization And Scent On Complete Blood Cell Count During Early Weaning Period, Mason Paladino May 2023

Effects Of Sow Vocalization And Scent On Complete Blood Cell Count During Early Weaning Period, Mason Paladino

Biological Sciences Undergraduate Honors Theses

Piglets are deprived of their sows’ touch, sound, and smell after weaning which results in biological stress. The present study investigated continuing exposure of sow vocalization and scent during the early weaning period on complete blood cell count. A total of 12 litters, 8 piglets (4 male and 4 female) per litter were selected at weaning and assigned to 1 of 4 experimental treatments: control, O (olfactory group with scent and no vocal stimulation), V (non-olfactory with vocal stimulation), VO (vocal stimulation and olfactory stimulation) as a 2x2 factorial arrangement. Vocal stimulation was emulated by an audio recording of the …

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Climate Change, Food Security, And The Myth Of Unlimited Abundance, Susan A. Schneider May 2023

Climate Change, Food Security, And The Myth Of Unlimited Abundance, Susan A. Schneider

Journal of Food Law & Policy

The Biden-Harris White House can be commended for convening the historic White House Conference on Hunger, Nutrition, and Health highlighting the critical connections between access to healthy food and sustaining a healthy population. This article explores the impact of climate change and seeks to fill a critical gap in the national discussion. It argues that dramatic changes are needed in the way we think about domestic food security and that meaningful change will be required to assure an adequate supply of healthy food, as envisioned by the White House Conference. It explores the impact of the changes to the climate …

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Studying The Phosphorylation Of Isocitrate Dehydrogenase In Humans, Hannah Smith May 2023

Studying The Phosphorylation Of Isocitrate Dehydrogenase In Humans, Hannah Smith

Chemistry & Biochemistry Undergraduate Honors Theses

Isocitrate dehydrogenase is an important enzyme in the citric acid cycle where it catalyzes the oxidative decarboxylation of isocitrate to alpha-ketoglutarate. While there are three isoforms of isocitrate dehydrogenase (IDH1, IDH2, and IDH3), this research will focus on IDH1. The phosphorylation of isocitrate dehydrogenase is a process that has been linked to the formation of both luminal-like and basal-like breast cancer. Despite these correlations, the mechanisms that cause breast cancer development are unknown. To examine this, an enzyme activity assay for each phosphorylation variant and crystallization were conducted. The results of these indicate that phosphorylation at each site (IDH1-T77, IDH1-S188, …

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Expression, Purification, And Characterization Of Fibroblast Growth Factor 19, Elizabeth Ford May 2023

Expression, Purification, And Characterization Of Fibroblast Growth Factor 19, Elizabeth Ford

Chemistry & Biochemistry Undergraduate Honors Theses

Fibroblast growth factors (FGFs) are a family of signaling proteins with diverse biological functions. Fibroblast growth factor 19 (FGF19) regulates several vital physiological processes, including bile acid, glucose, and lipid homeostasis. However, its therapeutic potential is limited by its structural instability. The purpose of this study is to express, purify, and characterize recombinant FGF19 to build the foundation for the creation of stable mutants, which can be used to treat a variety of common diseases including type 2 diabetes, atherosclerosis, and nonalcoholic fatty liver disease. The parameters for overexpression in Escherichia coli were optimized according to optical density, inducer concentration, …

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Expression, Characterization, And Investigation Of The Thermal Stability Of Fibroblast Growth Factor (Fgf) 19, Ridhikaanth Kalaiselvan May 2023

Expression, Characterization, And Investigation Of The Thermal Stability Of Fibroblast Growth Factor (Fgf) 19, Ridhikaanth Kalaiselvan

Chemistry & Biochemistry Undergraduate Honors Theses

Fibroblast growth factors are a family of cell signaling proteins that have the ability to bind to heparin and are involved in a wide range of physiological functions, such as angiogenesis, cell differentiation, cell proliferation, cell morphogenesis, and wound healing. Fibroblast growth factor (FGF) 19 is a signaling protein belonging to this large family of fibroblast growth factors (FGFs). FGF19 has a pronounced effect on various biological processes, including cell proliferation, cholesterol and lipid catabolism, and glucose homeostasis. As such, FGF19 is known to play an integral role in regulating many metabolic diseases, which piques the interest of the science …

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Low-Cost Microstereolithography 3d Printing With Microfluidic Microsampling Applications, Lauren Twombly May 2023

Low-Cost Microstereolithography 3d Printing With Microfluidic Microsampling Applications, Lauren Twombly

Chemistry & Biochemistry Undergraduate Honors Theses

The growing field of stereolithography 3D printing has welcomed a new age ofmicrofluidic device fabrication techniques. When compared to previous planar fabrication techniques such as soft-lithography, stereolithography 3D printing offers highly automated procedures, reduced fabrication times, and greater complexity of device features. To date, the greatest tradeoff for 3D printing in microfluidic device fabrication is poorer resolution when compared to soft-lithography which can produce feature sizes on the nanometer scale. The poorer resolution of 3D printing limits the feasible size of features. While highly sophisticated 3D printers are capable of achieving sub 10 μm resolution, these instruments are incredibly expensive …

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Determining The Effectiveness Of Rosemary Essential Oil On The Shelf Life Of Ground Beef Under Different Lighting Conditions, Jordan Looper May 2023

Determining The Effectiveness Of Rosemary Essential Oil On The Shelf Life Of Ground Beef Under Different Lighting Conditions, Jordan Looper

Animal Science Undergraduate Honors Theses

The objective of this study was to determine the effectiveness of rosemary extract on the shelf life of ground beef patties under different retail display conditions. Ground beef patties were produced from an 85% lean and 15% fat blend purchased from a local grocery retailer, finely ground through a 0.953 cm plate and separated into 151.2 g patties (n=64). Patties were randomly assigned into a control group (no antioxidants added) or a 0.20% concentration rosemary extract group. Patties were individually packaged using polyvinyl chloride overwrap. Antioxidant and control patties were randomly assigned into one of two lighting intensity …

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Environmental Injustice In Fayetteville, Arkansas: Investigating Unjust And Racist Conditions In Fayetteville's Industrial Park, Chloe Devecsery May 2023

Environmental Injustice In Fayetteville, Arkansas: Investigating Unjust And Racist Conditions In Fayetteville's Industrial Park, Chloe Devecsery

Architecture Undergraduate Honors Theses

Environmental racism refers to how minority neighborhoods are burdened with a disproportionate number of environmental hazards and pollution that lower the quality of life and create health disparities. Despite the growing awareness of the national and global problem, environmental injustice and racism can be found in nearly every place. There is little being done regarding policy, public awareness, and government action. The fight for environmental justice is still needed across America, in Arkansas, and in our community. This disciplinary-oriented capstone gives a brief overview of the environmental justice movement and uses publicly available maps and statistics from government and academic …

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Examining Differences In Adult Attachment Across Varying Family Dynamics, Hannah Miller May 2023

Examining Differences In Adult Attachment Across Varying Family Dynamics, Hannah Miller

School of Social Work Undergraduate Honors Theses

Recent research suggests that attachment in adulthood impacts many aspects of an individual’s life, including experiences with romantic partners, emotional regulation, and overall life satisfaction. Research attributes this to the levels of attachment anxiety and attachment avoidance individuals experience due to relationship experiences with their caregivers in childhood. The purpose of this study is to examine the relationship between specific family dynamics and the presence of attachment anxiety and avoidance in adulthood. The present study recruited 185 adults to participate in an anonymous survey about the family dynamics they experienced in childhood, including the relationship between their parents or guardians …

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Effect Of Soy Co-Products In Supplements For Grazing Cattle On Growth, Complete Blood Cell Counts, And Physiological Response Following A Lipopolysaccharide Challenge, Bralee Lansdell May 2023

Effect Of Soy Co-Products In Supplements For Grazing Cattle On Growth, Complete Blood Cell Counts, And Physiological Response Following A Lipopolysaccharide Challenge, Bralee Lansdell

Biological Sciences Undergraduate Honors Theses

The objective of this study was to determine the effect of soy co-products (soybean meal and soy oil) in the diet on the growth and hemocytology of cattle during a 56-day growing phase and the physiological/behavioral response to an endotoxin challenge. Angus crossbred steers (n = 36; 289 ± 31 kg, initial body weight ± SD) were stratified by body weight and sire; and assigned randomly to pastures (n = 9; 0.45 ha/mixed-grass pasture). Pastures were assigned randomly to 1 of 3 dietary treatments: 1) a control supplement containing no soy co-products, 2) a supplement containing soybean meal, or 3) …

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Early Life Stress Predicts Future Conduct Disorder In Adolescents, Savannah Ellis May 2023

Early Life Stress Predicts Future Conduct Disorder In Adolescents, Savannah Ellis

Biological Sciences Undergraduate Honors Theses

Early Life Stress (ELS) and adversity increase people’s risk for developing mental, social, or emotional dysregulation and disorders later in life. The objective of this study was to test whether ELS in adolescents could prospectively predict future conduct disorder. The study additionally tested potential neural mediators of the effect of ELS on future conduct disorder, and specifically targeted the structural connections from the anterior insula and medial prefrontal cortex to the Nucleus Accumbens (NAcc). Data for the project came from the Adolescent Brain Cognitive Development Study (ABCD study), which is a longitudinal multi-site consortium funded by the National Institutes of …

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