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University of Alabama at Birmingham

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Pathogen Manipulation Of Arabidopsis Interaction Networks, Timothy Howton Jan 2020

Pathogen Manipulation Of Arabidopsis Interaction Networks, Timothy Howton

All ETDs from UAB

Under normal conditions, plants devote resources for growth, development, and reproduction. These processes require finely tuned coordination between multiple physio logical pathways. In this dissertation, we explore the connectivity of these pathways as well as what happens when the plant is challenged by biotic stress such as a bacterial pathogen. We are able to use network biology approaches in conjunction with yeast two hybrid and BiFC assays to construct a network of leucine-rich repeat receptor kinases. Furthermore, we elucidated novel effector-host interactions through the aforementioned network. Lastly, we explored the role of the glyoxylate cycle, in particular peroxisomal citrate synthase …


Rna Polymerase I Elongation Kinetics: A Biochemical And Global Study Of A Cancer Therapeutic Target, Catherine Elizabeth Scull Jan 2020

Rna Polymerase I Elongation Kinetics: A Biochemical And Global Study Of A Cancer Therapeutic Target, Catherine Elizabeth Scull

All ETDs from UAB

My graduate research has focused on understanding the elongation kinetics of RNA polymerase I (Pol I), the enzyme responsible for synthesizing ribosomal RNA (rRNA), and defining how inhibition of ribosome biogenesis may be used as a cancer therapeutic strategy. Here, I have defined key biophysical features of Pol I and I have expanded the field’s understanding of Pol I elongation by: 1) characterizing the enzymatic properties of Pol I by mutational analysis of the polymerase itself, and by 2) elucidating the role of DNA sequence on Pol I arrest and nucleolytic cleavage activity. In recent years, Pol I has become …


Smoke Inhalation, Lung Function, And Heart Rate In Wildland Firefighters, Jordan E. Nelson Jan 2020

Smoke Inhalation, Lung Function, And Heart Rate In Wildland Firefighters, Jordan E. Nelson

All ETDs from UAB

Given the close proximity to the fire front and limited use of respiratory protection, wildland firefighters are exposed to elevated levels of biomass smoke during regular occupational shifts. Due to the complex composition of biomass smoke, the relationships relating biomass smoke exposure to health outcomes has yet to be elucidated. In addition to occupational exposures, increasing intensity of wildfire events may place communities within close proximity to wildfires at risk of biomass smoke exposure. This study aimed to assess exposures to biomass smoke particles and quantify respiratory and cardiovascular health responses during active fire events using novel monitoring techniques. Personal …


All Shook Up At A Basketball Game, January 1992, Uab Archives Jan 2020

All Shook Up At A Basketball Game, January 1992, Uab Archives

Images of the Month from UAB Archives

Image ID: P6.1, #1525a

All shook up at a basetball game, January 1992


"Dreams Of Hope" Concert Documentary, Co-Directed By Uab's Henry Panion Iii, To Air Nationwide In February, Shannon Thomason Dec 2019

"Dreams Of Hope" Concert Documentary, Co-Directed By Uab's Henry Panion Iii, To Air Nationwide In February, Shannon Thomason

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No abstract provided.


Anna Sorace, Ph.D., Named Director Of The Small Animal Imaging Facility, Mary Ashley Canevaro Dec 2019

Anna Sorace, Ph.D., Named Director Of The Small Animal Imaging Facility, Mary Ashley Canevaro

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No abstract provided.


Mesenchymal Niche-Specific Expression Of Cxcl12 Controls Quiescence Of Treatment-Resistant Leukemia Stem Cells, Mary Ashley Canevaro Dec 2019

Mesenchymal Niche-Specific Expression Of Cxcl12 Controls Quiescence Of Treatment-Resistant Leukemia Stem Cells, Mary Ashley Canevaro

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No abstract provided.


Get Creative In The New Year With New Arts Classes At Uab's Artplay, Shannon Thomason Dec 2019

Get Creative In The New Year With New Arts Classes At Uab's Artplay, Shannon Thomason

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No abstract provided.


Santa Spreads Holiday Cheer In Uab's Nicu, Alicia Rohan Dec 2019

Santa Spreads Holiday Cheer In Uab's Nicu, Alicia Rohan

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No abstract provided.


Mukhtar's Instruction Helps Students 'Feel We Can Truly Impact The World', Haley Herfurth Dec 2019

Mukhtar's Instruction Helps Students 'Feel We Can Truly Impact The World', Haley Herfurth

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No abstract provided.


5 Ways To Be A Healthy Holiday Party Pro, Staff Dec 2019

5 Ways To Be A Healthy Holiday Party Pro, Staff

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No abstract provided.


Uab's Aeiva Presents Artist Allyson Comstock, "Antarctica: A Disappearing Continent" From Jan. 13-March 21, Shannon Thomason Dec 2019

Uab's Aeiva Presents Artist Allyson Comstock, "Antarctica: A Disappearing Continent" From Jan. 13-March 21, Shannon Thomason

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No abstract provided.


5 Ways To Be A Healthy Holiday Party Pro, Adam Pope Dec 2019

5 Ways To Be A Healthy Holiday Party Pro, Adam Pope

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No abstract provided.


Faculty Projects Funded Through 2019 Multi-Pi Awards, Mary Ashley Canevaro Dec 2019

Faculty Projects Funded Through 2019 Multi-Pi Awards, Mary Ashley Canevaro

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No abstract provided.


Four From School Of Medicine Named Alabama Schweitzer Fellows, Mary Ashley Canevaro Dec 2019

Four From School Of Medicine Named Alabama Schweitzer Fellows, Mary Ashley Canevaro

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No abstract provided.


Privacy Alert: Brainwave Devices Can Leak Sensitive Medical Conditions And Personal Information, Alicia Rohan Dec 2019

Privacy Alert: Brainwave Devices Can Leak Sensitive Medical Conditions And Personal Information, Alicia Rohan

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No abstract provided.


Dean's Message: Season Of Gratitude, Selwyn M. Vickers Md Dec 2019

Dean's Message: Season Of Gratitude, Selwyn M. Vickers Md

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No abstract provided.


Works By Student-Artists On Show For 44th Annual Student Juried Exhibition, Jan. 13-March 14, 2020, Shannon Thomason Dec 2019

Works By Student-Artists On Show For 44th Annual Student Juried Exhibition, Jan. 13-March 14, 2020, Shannon Thomason

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No abstract provided.


Bae Selected For Most Promising Multicultural Student Program, First In Uab History, Brianna Hoge Dec 2019

Bae Selected For Most Promising Multicultural Student Program, First In Uab History, Brianna Hoge

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No abstract provided.


Sullivan Survivor Care Program Ready To Take Next Step, Adam Pope Dec 2019

Sullivan Survivor Care Program Ready To Take Next Step, Adam Pope

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No abstract provided.


Cancer Therapy May Be Aided By Induced Macropinocytosis, A Rarely Reported Form Of Cell Death, Jeff Hansen Dec 2019

Cancer Therapy May Be Aided By Induced Macropinocytosis, A Rarely Reported Form Of Cell Death, Jeff Hansen

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No abstract provided.


Optometry Gives Gift Of Sight At Annual Event, Haley Herfurth Dec 2019

Optometry Gives Gift Of Sight At Annual Event, Haley Herfurth

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No abstract provided.


$50,000 Grant To Uab's Arts In Medicine Program Will Support Workshops For Cancer Survivors, Shannon Thomason Dec 2019

$50,000 Grant To Uab's Arts In Medicine Program Will Support Workshops For Cancer Survivors, Shannon Thomason

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No abstract provided.


Recovering Trauma Patient With An Eye Toward Naval Career Vows To "Use Every Breath I Have To Help Others", Alicia Rohan Dec 2019

Recovering Trauma Patient With An Eye Toward Naval Career Vows To "Use Every Breath I Have To Help Others", Alicia Rohan

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No abstract provided.


Pediatric Brain Tumor Treatment At Uab Awarded Fda Grant For First-In-Human Study, Alicia Rohan Dec 2019

Pediatric Brain Tumor Treatment At Uab Awarded Fda Grant For First-In-Human Study, Alicia Rohan

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No abstract provided.


Nursing Expands Across The Ether, Haley Herfurth Dec 2019

Nursing Expands Across The Ether, Haley Herfurth

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No abstract provided.


About That New Sign At The Kaul Building..., Matt Windsor Dec 2019

About That New Sign At The Kaul Building..., Matt Windsor

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No abstract provided.


Restoring The Art Of Healing: Book Celebrates Palliative Care Work And Legacy, Alicia Rohan Dec 2019

Restoring The Art Of Healing: Book Celebrates Palliative Care Work And Legacy, Alicia Rohan

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No abstract provided.


Study Yields New Information About Dementia's Genetic Risk Factors, Alicia Rohan Dec 2019

Study Yields New Information About Dementia's Genetic Risk Factors, Alicia Rohan

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No abstract provided.


Atomic Force Microscope Awarded To Uab, Alicia Rohan Dec 2019

Atomic Force Microscope Awarded To Uab, Alicia Rohan

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No abstract provided.