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University of Alabama at Birmingham

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A Simple Plan, A Simple Faith: Chaplain And Local Congregant Strategies For Sharing Faith In The Prison Context, Jessica P. Shoemaker Jan 2008

A Simple Plan, A Simple Faith: Chaplain And Local Congregant Strategies For Sharing Faith In The Prison Context, Jessica P. Shoemaker

All ETDs from UAB

As the prison population in the United States continues to expand, so too has the use of faith-based prison programs as tools for correctional treatment. Using in-depth interviews with thirty current prison chaplains and local religious congregants in Mississippi, I explore the strategies and techniques used by prison ministry workers in their work with inmates. Two overarching themes emerged from the narratives of prison ministry work. The first is that the ministry workers were careful to avoid setting or focusing on numeric goals for religious conversions before interacting with the inmates. They reported that this approach was based on their …

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Night Moves, Jason Edward Slatton Jan 2008

Night Moves, Jason Edward Slatton

All ETDs from UAB

Night Moves, the title of this collection of poetry, will most likely be familiar to readers as derived from the FM radio staple by Detroit songwriter Bob Seger. Seger’s song is an attempt to understand and navigate a past that is essentially lost to him, and I see each of these poems as “night moves” in that I am writing to a past that is lost to me and that I am fervently attempting to in some way record. That this title is born of the rock and roll ethos is also certainly intentional; I spent a great deal of …

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Stochastic Energetics Of The Buttiker-Landauer Motor And Refrigerator, Ronald Benjamin Jan 2008

Stochastic Energetics Of The Buttiker-Landauer Motor And Refrigerator, Ronald Benjamin

All ETDs from UAB

We investigated the energetics of a Brownian motor driven by position dependent temperature, commonly known as the B¨uttiker-Landauer motor. Overdamped models (M = 0) predict that the motor can attain Carnot efficiency. However, the overdamped limit (M → 0), contradicts the previous prediction due to the kinetic energy contribution to the heat transfer. Using molecular dynamics simulation and numerical solution of the inertial Langevin equation, we confirmed that the motor can never achieve Carnot efficiency and verified that the heat flow via kinetic energy diverges asM−1/2 in the overdamped limit. The reciprocal process of the motor, namely the B¨uttiker-Landauer refrigerator …

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Diagnosing Antiretroviral Treatment Failure In Resource-Limited Settings, Ronald Alexander Cantrell Jan 2008

Diagnosing Antiretroviral Treatment Failure In Resource-Limited Settings, Ronald Alexander Cantrell

All ETDs from UAB

This dissertation had three central goals. The first was to review the existing literature for reports of virologic failure among adults initiating non-nucleoside reverse transcriptase inhibitor-based antiretroviral therapy in resource-limited settings. The second was to describe the epidemiology of virologic failure over the first 6 months of therapy in Lusaka, Zambia. The third was to examine the performance of different approaches for diagnosing virologic failure. We performed a meta-analysis using data from previously published reports to create summary estimates for the prevalence of virologic failure and found that the lowest estimate of the 95% confidence interval was 10% or higher …

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The Developmental Functions Of Bdnf And Mecp2 On Dendritic And Synaptic Structure, Christopher A. Chapleau Jan 2008

The Developmental Functions Of Bdnf And Mecp2 On Dendritic And Synaptic Structure, Christopher A. Chapleau

All ETDs from UAB

Mutations in the transcriptional repressor MeCP2 cause Rett Syndrome (RTT), a mental retardation disease associated with reduced dendritic architecture of cortical pyramidal neurons, in addition to a decrease in the number of dendritic spines. I present the first quantification analysis of spine density in postmortem human brain tissue, demonstrating that hippocampal CA1 pyramidal neurons have reduced spine densities in RTT patients throughout their lives. One gene that MeCP2 regulates is BDNF, an important developmental factor that modulates synaptic transmission and plasticity, as well as spine formation and maturation. In immature cultured hippocampal neurons, cell-autonomous expression of BDNF accelerates the differentiation …

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Enzymatic And Proteomic Analysis Of Spinal Cord In A G93a Als Mouse Model, Page Jones Jan 2008

Enzymatic And Proteomic Analysis Of Spinal Cord In A G93a Als Mouse Model, Page Jones

All ETDs from UAB

Mutations to copper,zinc superoxide dismutase (Cu,Zn SOD or SOD1) are the only known causes of amyotrophic lateral sclerosis (ALS), a neurodegenerative disorder characterized primarily by death of spinal motor neurons. While the molecular mechanisms responsible for motor neuron death in this disease remain to be elucidated, recent studies implicate mitochondrial dysfunction as a key factor in the pathogenesis of ALS. In support of this, we observed ALS-dependent alterations in key functions including creatine kinase activity and ATP levels, which could be linked to changes in the mitochondrial proteome. Importantly, extensive research efforts have failed to develop a treatment that significantly …

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Calmodulin Binding To Cellular Flice Like Inhibitory Protein Modulates Fas-Induced Signaling And Tumorigenesis In Cholangiocarcinoma, Pritish Subhash Pawar Jan 2008

Calmodulin Binding To Cellular Flice Like Inhibitory Protein Modulates Fas-Induced Signaling And Tumorigenesis In Cholangiocarcinoma, Pritish Subhash Pawar

All ETDs from UAB

Cholangiocarcinoma, a fatal tumor arising from biliary epithelium, has very poor 5-year survival rate due to lack of early diagnosis and effective therapies. Induction of the Fas-mediated apoptosis is a promising therapeutic target in this tumor. Studies from our group and others have indicated that Fas-expression correlates inversely with disease progression and that CaM-antagonists induce apoptosis in cholangiocarcinoma cells in a Fas related manner. Further, we reported a direct and dynamic interaction of CaM and Fas and that CaM is recruited into the Fas-stimulated death inducing signaling complex (DISC), suggesting a cross talk between Fas and CaM pathways. The studies …

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Food Handling Practices Of High-Risk Populations, Bobby Babak Rasulnia Jan 2008

Food Handling Practices Of High-Risk Populations, Bobby Babak Rasulnia

All ETDs from UAB

Populations such as the immuno-compromised (HIV/AIDS, chemotherapy, and transplant patients) and those with chronic conditions (gastric illness, cirrhosis, on anti-microbial therapy, antacid medication and steroid medications) are more susceptible to food borne illness. Examining differences in food handling practices and personal characteristics of high-risk groups verses the general population is the focus of this research. This study is based on secondary data from an established quantitative survey instrument developed and administered by the 2001 FDA Food Safety Survey. Descriptive, chi square, and logistic regression methods were used in the analysis. A statistically significant relationship was not found between health status …

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Numerical Simulation Of Radiative Heat Transfer, Babila Ramamoorthy Jan 2008

Numerical Simulation Of Radiative Heat Transfer, Babila Ramamoorthy

All ETDs from UAB

No abstract provided.

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Expression And Function Of Aqua Porins In Malignant And Non-Malignant Astrocytes, Eric S. Mccoy Jan 2008

Expression And Function Of Aqua Porins In Malignant And Non-Malignant Astrocytes, Eric S. Mccoy

All ETDs from UAB

No abstract provided.

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Science, Technology, And Portraiture: Justine Cooper's Rapt And Transformers, Amber Henson Jan 2008

Science, Technology, And Portraiture: Justine Cooper's Rapt And Transformers, Amber Henson

All ETDs from UAB

No abstract provided.

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Bayesian Genome-Wide Qtl Mapping For Multiple Traits, Samprit Banerjee Jan 2008

Bayesian Genome-Wide Qtl Mapping For Multiple Traits, Samprit Banerjee

All ETDs from UAB

No abstract provided.

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Role Of Variant Sialylation In Regulating Tumor Cell Behavior, Faheem M. Shaikh Jan 2008

Role Of Variant Sialylation In Regulating Tumor Cell Behavior, Faheem M. Shaikh

All ETDs from UAB

Many different tumors have been documented to have elevated levels of the enzyme ST6Gal I, a Golgi glycosyltransferase that adds α2-6 sialic acids to glycoproteins. Concurrently, upregulated ST6Gal I is associated with metastasis and poor patient prognosis. We initially showed that HD3 colonocytes made to express oncogenic-ras, a common mutation in colon carcinoma, have increased expression of ST6Gal I and elevated α2-6 sialylated integrins. Having established that ras regulates ST6Gal I expression in colon epithelial cells, we found that colonocytes carrying hyper α2-6 sialylated β1 integrins exhibit increased adhesion to and migration toward collagen I. Further, we found that β1 …

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Taking The Last Of The Sun, Jo Lecoeur Jan 2008

Taking The Last Of The Sun, Jo Lecoeur

Birmingham Poetry Review

p. 25

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One Big Self: An Investigation / The Kitchen Sink: New And Selected Poems, Matthew Ladd Jan 2008

One Big Self: An Investigation / The Kitchen Sink: New And Selected Poems, Matthew Ladd

Birmingham Poetry Review

pp. 48-54

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The Barbary Wars: American Independence In The Atlantic World, Christopher Null Jan 2008

The Barbary Wars: American Independence In The Atlantic World, Christopher Null

Vulcan Historical Review

pp. 102-105

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The Great Hinckley Hunt Of 1818, Susan Grimm Jan 2008

The Great Hinckley Hunt Of 1818, Susan Grimm

Birmingham Poetry Review

p. 18

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Vulcan Historical Review 12 (Front Matter), Vulcan Historical Review Staff Jan 2008

Vulcan Historical Review 12 (Front Matter), Vulcan Historical Review Staff

Vulcan Historical Review

No abstract provided.

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The Influence Of The Sexual Revolution, Katie Sutton Jan 2008

The Influence Of The Sexual Revolution, Katie Sutton

Vulcan Historical Review

pp. 74-84

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Capriccio At The Museum Of Art, John Hart Jan 2008

Capriccio At The Museum Of Art, John Hart

Birmingham Poetry Review

p. 21

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Nocturne, Stan Sanvel Rubin Jan 2008

Nocturne, Stan Sanvel Rubin

Birmingham Poetry Review

p. 39

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Boom And Bust In Townley: Case Study Of A Coal Mining Camp From 1920-1950, Tia Pavlovich Jan 2008

Boom And Bust In Townley: Case Study Of A Coal Mining Camp From 1920-1950, Tia Pavlovich

Vulcan Historical Review

pp. 58-73

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Why The "One Great City" Movement Failed, John Paul Whitmore Jan 2008

Why The "One Great City" Movement Failed, John Paul Whitmore

Vulcan Historical Review

pp. 85-94

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Untitled, Sudie Nostrand Jan 2008

Untitled, Sudie Nostrand

Birmingham Poetry Review

p. 36

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Miami Song, Andrew Glaze Jan 2008

Miami Song, Andrew Glaze

Birmingham Poetry Review

p. 16

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Intuition, Or Methods Of Transportation, Liz Robbins Jan 2008

Intuition, Or Methods Of Transportation, Liz Robbins

Birmingham Poetry Review

p. 38

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The Fight Against Hiv: An Interview With Dr. Michael Saag, Matt Morton Jan 2008

The Fight Against Hiv: An Interview With Dr. Michael Saag, Matt Morton

Inquiro (undergraduate research journal)

pp. 46-47

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Dr. David Graves: Exploring The Chemistry Of Nucleic Acids, Drew Buie Jan 2008

Dr. David Graves: Exploring The Chemistry Of Nucleic Acids, Drew Buie

Inquiro (undergraduate research journal)

pp. 48-49

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Dr. Perry Gerakines: Astrophysicist At Uab Investigates The Origins Of Life, Danuel Laan Jan 2008

Dr. Perry Gerakines: Astrophysicist At Uab Investigates The Origins Of Life, Danuel Laan

Inquiro (undergraduate research journal)

pp. 68-69

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Wear Testing Of Zirconia Coatings For Applications In Total Hip Replacement, Carrie Stewart, Alan Eberhardt Jan 2008

Wear Testing Of Zirconia Coatings For Applications In Total Hip Replacement, Carrie Stewart, Alan Eberhardt

Inquiro (undergraduate research journal)

pp. 71-75

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