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University of Alabama at Birmingham

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Rehabilitation Psychologists Provide Pathways To Quality Of Life For The Injured, Ill, Staff Sep 2017

Rehabilitation Psychologists Provide Pathways To Quality Of Life For The Injured, Ill, Staff

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No abstract provided.


National Program Supports Researchers In Hiv Prevention And Cardiovascular Disease, Staff Sep 2017

National Program Supports Researchers In Hiv Prevention And Cardiovascular Disease, Staff

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No abstract provided.


Experts Available To Discuss Health, Engineering And Economic Impacts Of Hurricanes, Staff Aug 2017

Experts Available To Discuss Health, Engineering And Economic Impacts Of Hurricanes, Staff

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No abstract provided.


State Launches Serious Infectious Disease Network, Staff Aug 2017

State Launches Serious Infectious Disease Network, Staff

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No abstract provided.


Birmingham Among 13 U.S. Cities Committed To End The Spread Of Aids By 2030, Staff Aug 2017

Birmingham Among 13 U.S. Cities Committed To End The Spread Of Aids By 2030, Staff

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No abstract provided.


Dismukes, 'Role Model To All,' Passes Away, Carolyn Walsh Jun 2017

Dismukes, 'Role Model To All,' Passes Away, Carolyn Walsh

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No abstract provided.


Donor Microbes Persist Up To Two Years After A Fecal Transplant To Treat Recurrent C. Difficile Infection, Jeff Hansen Jun 2017

Donor Microbes Persist Up To Two Years After A Fecal Transplant To Treat Recurrent C. Difficile Infection, Jeff Hansen

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No abstract provided.


Donor Microbes Persist Up To Two Years After A Fecal Transplant To Treat Recurrent C. Difficile Infection, Jeff Hansen Jun 2017

Donor Microbes Persist Up To Two Years After A Fecal Transplant To Treat Recurrent C. Difficile Infection, Jeff Hansen

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No abstract provided.


Risk Of Forgetting Medical Miracles: Measles Outbreak, Alicia Rohan Jun 2017

Risk Of Forgetting Medical Miracles: Measles Outbreak, Alicia Rohan

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No abstract provided.


New Faculty Fellowship To Expand Undergraduate Research Opportunities, Haley Herfurth Jun 2017

New Faculty Fellowship To Expand Undergraduate Research Opportunities, Haley Herfurth

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No abstract provided.


Uab Alumni And Faculty Add Zest To Birmingham's Rising Food Scene, Staff Jun 2017

Uab Alumni And Faculty Add Zest To Birmingham's Rising Food Scene, Staff

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No abstract provided.


New Research Unit Opens In Birmingham To Advance Treatment Of Childhood Disease, Staff May 2017

New Research Unit Opens In Birmingham To Advance Treatment Of Childhood Disease, Staff

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No abstract provided.


Undergraduate Students Gain Research Experience In Drug Discovery Lab, Staff Apr 2017

Undergraduate Students Gain Research Experience In Drug Discovery Lab, Staff

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No abstract provided.


Som Faculty Recognized For Exceptional Mentorship By Uab Graduate School, Uab Heersink School Of Medicine News Apr 2017

Som Faculty Recognized For Exceptional Mentorship By Uab Graduate School, Uab Heersink School Of Medicine News

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No abstract provided.


Alabama Vaccine Research Clinic At Uab Recruiting For Groundbreaking Hiv Prevention Research Trial, Jordan Lessley Apr 2017

Alabama Vaccine Research Clinic At Uab Recruiting For Groundbreaking Hiv Prevention Research Trial, Jordan Lessley

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No abstract provided.


Alabama Vaccine Research Clinic At Uab Recruiting For Groundbreaking Hiv Prevention Research Trial, Staff Mar 2017

Alabama Vaccine Research Clinic At Uab Recruiting For Groundbreaking Hiv Prevention Research Trial, Staff

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No abstract provided.


Uab Study Highlights Risks Of Sepsis, Staff Mar 2017

Uab Study Highlights Risks Of Sepsis, Staff

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No abstract provided.


New Uab Undergraduate Degree Programs In Genetics, Genomic Sciences And Immunology Now Enrolling, Staff Mar 2017

New Uab Undergraduate Degree Programs In Genetics, Genomic Sciences And Immunology Now Enrolling, Staff

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No abstract provided.


More Than 1,100 Employees To Be Honored During Annual Service Awards, Haley Herfurth Feb 2017

More Than 1,100 Employees To Be Honored During Annual Service Awards, Haley Herfurth

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No abstract provided.


Majoring In Defense: Uab's New Undergraduate Immunology Program, Matt Windsor Feb 2017

Majoring In Defense: Uab's New Undergraduate Immunology Program, Matt Windsor

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No abstract provided.


February 14, 2017 Ereporter, University Of Alabama At Birmingham Feb 2017

February 14, 2017 Ereporter, University Of Alabama At Birmingham

eReporter (campus newsletter)

No abstract provided.


Peruvian Native To Lead Top Global Tropical Medicine Training Center At Uab, Staff Feb 2017

Peruvian Native To Lead Top Global Tropical Medicine Training Center At Uab, Staff

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No abstract provided.


Lewis Is A Master Of Everything Thrown At Her, Haley Herfurth Feb 2017

Lewis Is A Master Of Everything Thrown At Her, Haley Herfurth

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No abstract provided.


World-Renowned Immunologist To Speak At 2017 Bertram M. Marx Lecture, Uab Heersink School Of Medicine News Jan 2017

World-Renowned Immunologist To Speak At 2017 Bertram M. Marx Lecture, Uab Heersink School Of Medicine News

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No abstract provided.


The Truth About Vaccines: They Are Safe, And They Save Lives, Tyler Greer Jan 2017

The Truth About Vaccines: They Are Safe, And They Save Lives, Tyler Greer

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No abstract provided.


Uab Magazine - Spring 2017, University Of Alabama At Birmingham Jan 2017

Uab Magazine - Spring 2017, University Of Alabama At Birmingham

UAB Magazine

No abstract provided.


The Function Of Protein Kinase Ck2 In Cd4 T Cell Differentiation And Autoimmunity, Sara Ann Gibson Jan 2017

The Function Of Protein Kinase Ck2 In Cd4 T Cell Differentiation And Autoimmunity, Sara Ann Gibson

All ETDs from UAB

Protein kinase CK2 is a highly conserved serine/threonine kinase essential for cell viability. CK2 exhibits immense pleiotropy and has well characterized interactions with canonical cytosolic signaling pathways such as PI3K/Akt/mTOR and JAK/STAT. These pathways are critical for CD4+ T cell function, and further are known to be aberrantly active in the T cell-driven autoimmune disease Multiple Sclerosis, but little is known as to how CK2 functions in CD4+ T cells or in the context of autoimmune diseases. The current dissertation examines the understudied T cell-specific functions of CK2 utilizing two approaches, pharmacologic inhibition and genetic deletion. We discovered CK2 to …


N-Acetyl-D-Glucosamine-Reactive Natural Antibodies: Roles In Suppression Of Autoimmune Diabetes And Environmental Factors Influencing Their Development, James Stewart New Jan 2017

N-Acetyl-D-Glucosamine-Reactive Natural Antibodies: Roles In Suppression Of Autoimmune Diabetes And Environmental Factors Influencing Their Development, James Stewart New

All ETDs from UAB

Type 1 Diabetes suppression in diabetes prone mice following immunization with Group A Streptococcus correlates with the B lymphocyte response to N-acetyl-D-glucosamine (GlcNAc) present in the Group A Carbohydrate cell wall polysaccharide. GlcNAc-specific B cells recognize cryptic GlcNAc-epitopes in beta cells. Following exposure of GlcNAc-modified antigens on beta cells during cellular apoptosis, GlcNAc-specific IgM antibodies opsonize these epitopes and mediate classical complement pathway activation. In vitro, opsonization of apoptotic beta cells with GlcNAc-specific IgM increases their uptake by dendritic cells, while suppressing the subsequent presentation of beta cell-derived antigens to diabetogenic T lymphocytes. Passive administration of Group A Streptococcus antisera …


The Use Of Web Computing To Solve Modern Data Problems In Science And Medicine, Alex M. Dussaq Jan 2017

The Use Of Web Computing To Solve Modern Data Problems In Science And Medicine, Alex M. Dussaq

All ETDs from UAB

Modern day research in science and medicine has become dominated by the ideas of 'Big Data'. Life science data have become progressively more complex and the rate at which it is generated continues to accelerate. This combination of complexity and genera- tion speed creates a multitude of informatics problems to solve. We believe that among the many issues facing modern data scientists, there exists a substantial subset that can only be satisfactorily solved utilizing web computing. Of these web specific issues, we have chosen to focus primarily on data storage and retrieval, data privacy, and data visualization. We present here …


Activation Of Ampk To Diminish Sepsis-Induced Lung Injury, Nathaniel Bone Jan 2017

Activation Of Ampk To Diminish Sepsis-Induced Lung Injury, Nathaniel Bone

All ETDs from UAB

Sepsis is the most frequent cause of death of hospitalized patients in modern ICUs. Severe infection, trauma, hemorrhage, burns, and surgery are significant causes of multi-organ injury and immune dysfunction that in turn primes for a high risk of secondary lung infections. In addition to detrimental inflammation, sepsis is linked to loss of metabolic plasticity due to mitochondrial dysfunction in immune cells and lung tissue. In particular, mitochondrial failure in lungs of critically ill septic patients is correlated with high mortality rates. We proposed that AMP-activated protein kinase (AMPK) activation, a major bioenergetic sensor and metabolic regulator, is a plausible …