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University of Alabama at Birmingham

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Investigating Cardiovascular Health Among Asian Americans, Adam Pope Jun 2019

Investigating Cardiovascular Health Among Asian Americans, Adam Pope

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No abstract provided.


Endowments Named For Coleman And Corman, Coleman Honored By Masa, Brit Blalock May 2019

Endowments Named For Coleman And Corman, Coleman Honored By Masa, Brit Blalock

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No abstract provided.


New Trial Set To Determine Efficacy Of Long-Acting Hiv Medication In At-Risk Group, Alicia Rohan May 2019

New Trial Set To Determine Efficacy Of Long-Acting Hiv Medication In At-Risk Group, Alicia Rohan

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No abstract provided.


Uab Is One Of Seven Sites Worldwide In Hiv-Prevention Trial, Alicia Rohan May 2019

Uab Is One Of Seven Sites Worldwide In Hiv-Prevention Trial, Alicia Rohan

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No abstract provided.


Measles Outbreak Prompts Physician Recommendations, Support For Vaccinations, Alicia Rohan Apr 2019

Measles Outbreak Prompts Physician Recommendations, Support For Vaccinations, Alicia Rohan

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No abstract provided.


$17 Million Grant Will Explore Immune Cells In Inaccessible Tissues Of The Human Body, Jeff Hansen Apr 2019

$17 Million Grant Will Explore Immune Cells In Inaccessible Tissues Of The Human Body, Jeff Hansen

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No abstract provided.


$37.5 Million Grant Will Address Research Of High-Priority Infections, Alicia Rohan Mar 2019

$37.5 Million Grant Will Address Research Of High-Priority Infections, Alicia Rohan

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No abstract provided.


Saag Sworn In As Member Of Presidential Advisory Council Of Hiv/Aids, Staff Mar 2019

Saag Sworn In As Member Of Presidential Advisory Council Of Hiv/Aids, Staff

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No abstract provided.


School Of Medicine And Southern Research Launch Three Collaborative Pilot Studies, Jeff Hansen Feb 2019

School Of Medicine And Southern Research Launch Three Collaborative Pilot Studies, Jeff Hansen

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No abstract provided.


$3.25 Million R01 Grant Will Explore The Long-Term Impact Of Diet, Exercise On Symptoms Of Adults With Hiv, Staff Jan 2019

$3.25 Million R01 Grant Will Explore The Long-Term Impact Of Diet, Exercise On Symptoms Of Adults With Hiv, Staff

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No abstract provided.


Leading Researcher Returns To Discuss Origins Of Human Aids And Malaria At Uab's Darwin Day, Staff Jan 2019

Leading Researcher Returns To Discuss Origins Of Human Aids And Malaria At Uab's Darwin Day, Staff

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No abstract provided.


Elopre Named Director Of Diversity And Inclusion For Graduate Medical Education, Brit Blalock Jan 2019

Elopre Named Director Of Diversity And Inclusion For Graduate Medical Education, Brit Blalock

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No abstract provided.


"Precision Pathology" Brought Into Focus In Second Edition Of Textbook With Netto As Editor, Staff Jan 2019

"Precision Pathology" Brought Into Focus In Second Edition Of Textbook With Netto As Editor, Staff

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No abstract provided.


Uab Magazine - Fall 2019/Winter 2020, University Of Alabama At Birmingham Jan 2019

Uab Magazine - Fall 2019/Winter 2020, University Of Alabama At Birmingham

UAB Magazine

No abstract provided.


Classic Findings May Not Be Typical: A Rare Case Of Cutaneous Larva Migrans, Andrei Lojek, Erin Britt, Ali Hassoun Jan 2019

Classic Findings May Not Be Typical: A Rare Case Of Cutaneous Larva Migrans, Andrei Lojek, Erin Britt, Ali Hassoun

UAB Huntsville Research Day - All Presentations

2019 clinical vignette poster


Recurrent Falls In A Patient With Suspected Ovarian Cancer: A Rare Case Of Lower Extremity Weakness, Noaman Ahmad, Aadil Lodhi, Ali Hassoun Jan 2019

Recurrent Falls In A Patient With Suspected Ovarian Cancer: A Rare Case Of Lower Extremity Weakness, Noaman Ahmad, Aadil Lodhi, Ali Hassoun

UAB Huntsville Research Day - All Presentations

2019 clinical vignette poster


Influenza 2017-2018, Rohini Ramamoorthy, Soujanya Thummathati, Bhavyaa Bahl, Ali Hassoun Jan 2019

Influenza 2017-2018, Rohini Ramamoorthy, Soujanya Thummathati, Bhavyaa Bahl, Ali Hassoun

UAB Huntsville Research Day - All Presentations

2019 oral presentation


A Curious Case Of Eosinophilia, Elizabeth Thottacherry, Ali Hassoun Jan 2019

A Curious Case Of Eosinophilia, Elizabeth Thottacherry, Ali Hassoun

UAB Huntsville Research Day - All Presentations

2019 oral presentation


Vagal Mediated Heart Rate Variability And Cognitive Impairments In Hiv-Seropositive Women, William C. Nicholson Jan 2019

Vagal Mediated Heart Rate Variability And Cognitive Impairments In Hiv-Seropositive Women, William C. Nicholson

All ETDs from UAB

Regardless of sufficient viral suppression, HIV exerts an ongoing inflammatory process that promotes chronic autonomic nervous system (ANS) dysfunction, accelerates physiological aging, and increases the risk of developing a spectrum of cognitive disorders (known as HIV-associated neurocognitive disorders [HAND]). Given this, identifying pathological mediators of this inflammatory response could provide insight into the mechanisms driving HAND. The vagus nerve (indexed by vagal-mediated heart rate variability [vmHRV]) could provide such a mediator as it regulates ANS activity via reciprocal cardio-neural pathways, which regulate inflammation and homeostasis. Vagal dysfunction is associated with persistent inflammatory signaling (e.g., stress or inflammatory-based disorders [such as …


Early Life Stress And Immune Responses In Adult Rat Kidneys, Ijeoma E. Obi Jan 2019

Early Life Stress And Immune Responses In Adult Rat Kidneys, Ijeoma E. Obi

All ETDs from UAB

Globally, human studies show overwhelming associations between adverse childhood experiences and cardiovascular disease (CVD) and CVD risks throughout adult life. As early as 6 years old, there are significant associations between childhood adversity and inflammation, and those association are observed throughout adult life as well. Over a decade ago, rodent models were used to establish the importance of the immune cells in hypertension, which is the major risk factor in developing CVD. Although these associations in humans are important, they pose several limitations that can be overcome by the use of animal models to study the molecular mechanisms that are …


Hpv And Hsv Associated Clinical Conditions Among People Living With Hiv-1 Infection, Yuanfan Ye Jan 2019

Hpv And Hsv Associated Clinical Conditions Among People Living With Hiv-1 Infection, Yuanfan Ye

All ETDs from UAB

This dissertation research focuses on investigating health burdens of HPV- and HSV- associated clinical conditions (CC) in people living with HIV-1 infection (PLWH) in the Southeastern United States. I designed a retrospective study using the UAB 1917 HIV Clinic Cohort. Electronic health records of PLWH attending the clinic for HIV-care between January 2006 and March 2019 were obtained and reviewed. I first examined incidence rates and trends of anogenital HPV- and HSV-associated CC. Then I adopted a new algorithm to group longitudinal CD4 cell counts based on their trajectories. I compared it with nadir and median CD4 cell counts in …


Exploring The Link Between Dietary Fiber, The Gut Microbiota And Estrogen Metabolism Among Women With Breast Cancer, Ayse G. Zengul Jan 2019

Exploring The Link Between Dietary Fiber, The Gut Microbiota And Estrogen Metabolism Among Women With Breast Cancer, Ayse G. Zengul

All ETDs from UAB

Breast cancer continues to be a very prevalent disease and impacts over 260,000 new patients per year in the United States. The gut microbiota composition may affect breast cancer risk by modulating various hormonal metabolites including endogenous estrogens. Dietary factors impact gut microbial ecology and influence the regulation of estrogen metabolism. Current evidence supports the potential role of dietary fiber in breast cancer prevention and its possible modulating influence on serum estrogen levels through the gut microbiota associated with β-glucuronidase activity. However, this mechanism is not clearly understood. In this study, we aimed to explore the associations between dietary fiber, …


A Case Study In The Effective Diagnosis Of Infectious Esophagitis, Bryan B. Grissett, Ali Hassoun Jan 2019

A Case Study In The Effective Diagnosis Of Infectious Esophagitis, Bryan B. Grissett, Ali Hassoun

UAB Huntsville Research Day - All Presentations

2019 clinical vignette poster


Cryptococcal Pneumonia In An Immunocompetent Host, Mohamed Hasan, Ali Hassoun Jan 2019

Cryptococcal Pneumonia In An Immunocompetent Host, Mohamed Hasan, Ali Hassoun

UAB Huntsville Research Day - All Presentations

2019 clinical vignette poster


Brain Abscess Mimicking Brain Neoplasm Presentation, Sabrina Martosz, Ali Hassoun Jan 2019

Brain Abscess Mimicking Brain Neoplasm Presentation, Sabrina Martosz, Ali Hassoun

UAB Huntsville Research Day - All Presentations

2019 clinical vignette poster


"Syphilips", Dallas Moran, Erin Baldwin, Haley Gates, Katherine Moody, Rajalakshmi Cheerla Jan 2019

"Syphilips", Dallas Moran, Erin Baldwin, Haley Gates, Katherine Moody, Rajalakshmi Cheerla

UAB Huntsville Research Day - All Presentations

2019 clinical vignette poster


Burger And Aki From Uncommon Cause, Jaime Alejandro Peña Garcia, Sabrina Matosz, Parekha Yedla Jan 2019

Burger And Aki From Uncommon Cause, Jaime Alejandro Peña Garcia, Sabrina Matosz, Parekha Yedla

UAB Huntsville Research Day - All Presentations

2019 clinical vignette poster


Structural Studies Of Some Proteins Responsible For Bacterial Pathogenesis, Kartik Manne Jan 2019

Structural Studies Of Some Proteins Responsible For Bacterial Pathogenesis, Kartik Manne

All ETDs from UAB

A wide range of infections is attributed to the pathogenesis of Gram-positive bacteria. The emergence of multi-drug-resistant Gram-positive pathogens has been a significant health concern and present serious therapeutic challenges globally. Some of the common Gram-positive bacterial species like Streptococcus pneumonia, Group B Streptococcus, and Staphylococcus aureus are infectious by employing several virulence factors for initial adhesion, colonization, biofilm initiation and dispersion, complement evasion, nutrient acquisition, and infection. The structural insights into these virulence factors are essential for understanding their mode of action, and also for developing a new class of antibiotics; a significant interest of many researchers. Pneumococcal adhesive …


Reported Clinical And Financial Performance Of Hospitals With Physician Ceos Compared To Those With Nonphysician Ceos, Leon Moores Jan 2019

Reported Clinical And Financial Performance Of Hospitals With Physician Ceos Compared To Those With Nonphysician Ceos, Leon Moores

All ETDs from UAB

Leaders impact organizational behavior and performance, and CEOs may have greater impact via numerous proposed mechanisms. Because of this, organizations expend considerable resources recruiting and selecting CEOs and may benefit from information suggesting a positive impact on organizational performance based upon measurable CEO characteristics. Little work has been done comparing the performance of hospitals with physician CEOs versus non-physician CEOs, in spite of the ease of identification of this characteristic and extant leadership theories suggesting a relationship between technical expertise and success in leading highly technical organizations. We compared multiple measures of reported clinical and financial performance and our linear …


Determination Of The Role Of Smu_833 In The Fitness And Virulence Of Cariogenic Streptococcus Mutans, Katherine Lynn Rainey Jan 2019

Determination Of The Role Of Smu_833 In The Fitness And Virulence Of Cariogenic Streptococcus Mutans, Katherine Lynn Rainey

All ETDs from UAB

Dental caries, commonly known as tooth decay, is the most common infectious disease worldwide. The main etiological agent of dental caries is Streptococcus mutans which can readily form a biofilm on the surface of teeth and produce acids through the metabolism of dietary sugars, which is largely responsible for the demineralization and subsequent destruction of tooth enamel. In addition, S. mutans synthesizes extracellular glucosyltransferases (Gtfs) capable of breaking apart dietary sucrose and polymerizing the glucose subunits into the sticky glucan matrix of the biofilm, imperative for the formation of robust, three-dimensional biofilms. Currently used caries therapies are not species-specific and …