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Articles 151 - 180 of 14418
Full-Text Articles in Entire DC Network
February 3, 2026 Ereporter, University Of Alabama At Birmingham
February 3, 2026 Ereporter, University Of Alabama At Birmingham
eReporter (campus newsletter)
No abstract provided.
Daily Coping Strategies, Unmet Needs And Daily Health Outcomes Among Family Caregivers Of Persons Living With Alzheimer's Disease And Related Dementias, Henrietta Armah Bennett
Daily Coping Strategies, Unmet Needs And Daily Health Outcomes Among Family Caregivers Of Persons Living With Alzheimer's Disease And Related Dementias, Henrietta Armah Bennett
ETDs from 2020-2029
Providing care for an individual with Alzheimer’s Disease and Related Dementias (ADRD) is considered the most stressful type of family caregiving that impacts caregivers’ health. More than one in five ADRD family caregivers report their overall health as poor to fair. These adverse health outcomes are often exacerbated when caregivers’ emotional, informational, and practical needs remain unmet throughout the caregiving trajectory. Numerous studies have shown that the ways in which caregivers cope to caregiving-related stressors significantly shape their health outcomes. Despite this evidence, a clear and consistent understanding of caregivers’ own appraisals of their unmet needs, coping strategies and mental …
Uab Libraries News, 02 2026, Uab Libraries
January 30, 2026 Ereporter, University Of Alabama At Birmingham
January 30, 2026 Ereporter, University Of Alabama At Birmingham
eReporter (campus newsletter)
No abstract provided.
Unpacking A Health Paradox Among Preterm Infants: Insights From A Providers' Perception, Brittany Nicole Stewart
Unpacking A Health Paradox Among Preterm Infants: Insights From A Providers' Perception, Brittany Nicole Stewart
ETDs from 2020-2029
The goal of this dissertation is to examine the varying perspectives, or frames, of providers regarding decision-making in the NICU, which includes how they view neonates and their families, their roles as providers, and the way their frames possibly impact the care they give to the infants. In this dissertation, I conduct in-depth interviews with 34 NICU providers and professionals that provide their services in the NICU, including doctors, nurse practitioners, nurses, various therapists (i.e. respiratory, physical, occupational), and two other providers from two other professions. Within the NICU, a common stereotype exists that is a belief that White boy …
The Perception Of Fentanyl’S Harm, Rachel Antenucci
The Perception Of Fentanyl’S Harm, Rachel Antenucci
ETDs from 2020-2029
While drug overdose deaths have generally decreased in the past year, close to 60,000 overdoses involving opioids occurred in 2024. The opioid crisis has lasted over two decades and is now in the fourth wave. The fourth wave has been characterized by overdoses resulting from fentanyl adulteration in the drug supply and polysubstance overdoses involving fentanyl. The purpose of the current study is to compare the perceived harm of fentanyl to other drugs of abuse and identify differences in the perceived harm of fentanyl between groups of people who use substances. An online survey was conducted across 15 states in …
Nilotinib-Mediated Reprogramming Of Bone Marrow Macrophages Alters Hematopoietic Stem Cell Fate In Chronic Myeloid Leukemia, Tiffany Davia Ricketts
Nilotinib-Mediated Reprogramming Of Bone Marrow Macrophages Alters Hematopoietic Stem Cell Fate In Chronic Myeloid Leukemia, Tiffany Davia Ricketts
ETDs from 2020-2029
Tyrosine kinase inhibition (TKI) is highly effective and promotes favorable long-term outcomes for many patients with chronic myeloid leukemia (CML). However, many patients experience treatment resistance or recurrence after TKI cessation due to leukemic stem cell (LSC) persistence within the hematopoietic stem cell (HSC) niche. Within the niche, macrophages adopt different activation states to alter HSC function, however, CML disrupts niche signals to selectively support LSCs and macrophages may contribute to this process. We hypothesize that macrophages contribute to pro-inflammatory activation within the niche to promote LSC development and nilotinib will reprogram macrophages to selectively support non-leukemic stem cells. To …
Conserved Chromatin Programs Orchestrate Cardiac Cell States In Health And Disease And Drive Cardiomyocyte Proliferation After Injury, Xiaoxiao Geng
Conserved Chromatin Programs Orchestrate Cardiac Cell States In Health And Disease And Drive Cardiomyocyte Proliferation After Injury, Xiaoxiao Geng
ETDs from 2020-2029
Chromatin structure is a central regulator of gene expression and cellular identity, yet the chromatin structural factors driving cardiac disease and regeneration remain incompletely defined. This dissertation investigates how modulation of chromatin architecture shapes pathological and regenerative cardiac phenotypes through integrated single-cell transcriptomic, epigenomic, and functional analyses. To determine whether chromatin structural regulators distinguish healthy from diseased cardiac states, we curated a comprehensive list of chromatin structural genes and applied it to single-nuclei RNA sequencing datasets from human hearts with and without dilated cardiomyopathy (DCM). Chromatin structural gene expression effectively stratified cardiomyocyte and fibroblast populations by disease status. Diseased cardiomyocytes …
Assessment Of Parental Knowledge And Anxiety Surrounding The Informed Consent Discussion For Neonatal Cardiac Interventions, Kristal Mancuso Hock
Assessment Of Parental Knowledge And Anxiety Surrounding The Informed Consent Discussion For Neonatal Cardiac Interventions, Kristal Mancuso Hock
ETDs from 2020-2029
The purpose of this dissertation was to explore the complexities of the informed consent (IC) process in the context of neonatal cardiac interventions, with a focus on parental knowledge and anxiety during decision-making. Across three manuscripts, this work examined conceptual dimensions, feasibility, and acceptability of a new prenatal treatment (palliative care (PC) support sessions), and the effect sizes of this new treatment on parental knowledge and anxiety levels surrounding the IC discussion for neonatal cardiac palliations. The first manuscript employed dimensional analysis to conduct a concept analysis of IC in surgical care. The review of 27 publications revealed three distinct …
January 27, 2026 Ereporter, University Of Alabama At Birmingham
January 27, 2026 Ereporter, University Of Alabama At Birmingham
eReporter (campus newsletter)
No abstract provided.
Expanding Access To Live Donation Opportunities: Implementing Telehealth Solutions To Enhance The Living Donor Navigator Program, Alexis Carter
Expanding Access To Live Donation Opportunities: Implementing Telehealth Solutions To Enhance The Living Donor Navigator Program, Alexis Carter
ETDs from 2020-2029
Living donor kidney transplantation (LDKT) is the most effective treatment for patients with end-stage kidney disease; however, living donation rates have remained suboptimal over the past two decades. As a result, many interventions have been developed and tailored to increase living donation. The Living Donor Navigator (LDN) Program is one effort designed to help transplant candidates identify potential living donors and guide them through the donation process, using a combination of advocacy and systems training. The LDN Program is a lay-navigator-based intervention that equips participants with the knowledge, communication skills, and confidence needed to identify and engage potential living donors. …
Novel Retinal Biomarker Development In Early Alzheimer’S Disease, Swetha Ravichandran
Novel Retinal Biomarker Development In Early Alzheimer’S Disease, Swetha Ravichandran
ETDs from 2020-2029
Alzheimer’s disease is a progressive neurodegenerative disorder that causes damage to the neurons that are present in the brain. Progress in the management and treatment of AD is limited by lack of early diagnostics, which are critical to the development of effective therapies. It is therefore critical to develop non-invasive/cost efficient biomarkers to aid in early diagnosis and interventions to prevent or delay dementia onset. While Positron Emission Tomography (PET) and cerebrospinal fluid assessment have greatest utility, they are not routinely used because they are expensive and invasive, respectively. Retinal imaging offers a promising, low-cost, and non-invasive avenue for detecting …
Early Life Stress Mediates Cardiovascular Disease Risk Through Csf1r And Increases Risk Of Lupus Through Mature B-Cells, Cailin Elizabeth Kellum
Early Life Stress Mediates Cardiovascular Disease Risk Through Csf1r And Increases Risk Of Lupus Through Mature B-Cells, Cailin Elizabeth Kellum
ETDs from 2020-2029
The term Early Life Stress (ELS) encompasses traumatic events occurring before the age of 18 such as physical abuse, verbal abuse, household dysfunctions, sexual abuse, childhood neglect, child maltreatment, and adverse childhood experiences. The traumatic psychological and physical experiences in early life are widely known to cause enduring effects on mental and physical health in adulthood. Of note, individuals with ELS have adverse health outcomes earlier in adulthood and with more severity such as in the case of Systemic Lupus Erythematous (SLE), an autoimmune disease. The risk for autoimmunity and cardiovascular disease (CVD) increases with ELS exposure and CVD is …
Awareness And Knowledge Of Juvenile Idiopathic Arthritis Among Orthodontic And Oral And Maxillofacial Surgery Specialties In The United States., Kavita Nayar
ETDs from 2020-2029
Introduction: Juvenile Idiopathic Arthritis (JIA) is the most common chronic pediatric arthritis, frequently involving the temporomandibular joint (TMJ) and resulting in facial growth disturbances, functional impairment, and complex multidisciplinary treatment needs. Despite its clinical relevance, limited awareness and inconsistent management strategies exist among specialists who are involved in the care of these patients including orthodontists, oral and maxillofacial surgeons and rheumatologists. This study aimed to evaluate the understanding, knowledge and interdisciplinary management practices between board-certified orthodontists and oral and maxillofacial surgeons (OMSs) across the United States regarding JIA. Materials and Methods: A cross-sectional survey was distributed electronically via Qualtrics to …
Relationship Between Corneal Biomechanics In Sjögren’S Disease And Risk Factors For Glaucoma Development, Isabella Grace Simmons
Relationship Between Corneal Biomechanics In Sjögren’S Disease And Risk Factors For Glaucoma Development, Isabella Grace Simmons
ETDs from 2020-2029
Both Sjögren’s disease and glaucoma are known to have abnormal corneal biomechanics that impact their disease progression. The pathophysiology of Sjögren’s disease may also increase the likelihood of developing glaucoma. However, we do not yet know whether the prevalence of risk factors associated with glaucoma in Sjögren’s patients is due to underlying weakened corneal biomechanics. Oculus Corvis ST will be used to evaluate the corneal biomechanics in Sjögren’s patients in relation to the inflammatory mediators in the tear film. These properties will then be correlated with retinal nerve fiber layer and ganglion cell layer thickness. Evaluating these findings will provide …
Lmod1 Modulates Neointimal Lesion Size After Vessel Injury And Stabilizes Smooth Muscle Cell Gene Regulatory Networks During Atherogenic Stress, Sara Wennersten
Lmod1 Modulates Neointimal Lesion Size After Vessel Injury And Stabilizes Smooth Muscle Cell Gene Regulatory Networks During Atherogenic Stress, Sara Wennersten
ETDs from 2020-2029
Phenotypic switching of smooth muscle cells (SMCs) from a contractile to a synthetic state underlies the pathogenesis of several cardiovascular disease (CVD) pathologies, including restenosis and atherosclerosis. Leiomodin 1 (LMOD1), an SMC-enriched actin-binding protein, has been previously found to regulate SMC phenotypic modulation in vitro. However, its contribution to CVD development and progression, along with its influence on gene regulatory networks (GRNs) that inform underlying responses to stress, remains incompletely defined. Here, I combine a mouse injury model, bulk RNA sequencing, and GRN inference to define how reduced LMOD1 expression perturbs SMC physiology during vascular wall remodeling and lipid stress. …
Characterization Of Social Media Use Patterns Among Hispanic/Latinx Dementia Caregivers And Its Impact On Mental Health, Sofia Mildrum Chana
Characterization Of Social Media Use Patterns Among Hispanic/Latinx Dementia Caregivers And Its Impact On Mental Health, Sofia Mildrum Chana
ETDs from 2020-2029
Hispanic & Latinx (H&L) family caregivers of people living with Alzheimer’s disease and related dementias (ADRDs) experience high levels of stress that can negatively impact their mental health and may turn to social networking sites (SNS, commonly known as ‘social media’) for coping or social support. However, no research has yet examined how SNS use influences H&L caregiver mental health. The primary purpose of the present study was to characterize patterns of SNS use among H&L ADRD family caregivers and examine the associations between SNS use and caregivers’ mental health and well-being. Data for the present study come from the …
Exploring The Relationship Among Nurse-Specific Factors And Triage Accuracy In The Emergency Setting, Krisada Suamchaiyaphum
Exploring The Relationship Among Nurse-Specific Factors And Triage Accuracy In The Emergency Setting, Krisada Suamchaiyaphum
ETDs from 2020-2029
Triage is a critical function of emergency nursing practice, directly influencing patient safety, flow, and outcomes in the emergency department (ED). Despite widespread use of standardized triage training and resources, triage accuracy among ED nurses remains suboptimal. The purpose of this three-manuscript dissertation was to examine factors associated with triage accuracy in the ED setting. Manuscript One was an integrative literature review of 14 studies published between 2011 and 2021, with reported triage accuracy rates ranging from 59.3% to 82%. Primary factors associated with triage accuracy were: nurse-specific, patient, and work environment factors. Manuscript Two reported a retrospective study of …
The Influence Of The Mental Health Parity And Addiction Equity Act On Residential Behavioral Healthcare Facility Availability In The United States: A State-Level Analysis, Amanda Mellowspring
The Influence Of The Mental Health Parity And Addiction Equity Act On Residential Behavioral Healthcare Facility Availability In The United States: A State-Level Analysis, Amanda Mellowspring
ETDs from 2020-2029
The need for accessible, quality behavioral healthcare (BH) has increased dramatically over recent decades. The availability of BH services for patients has long been complicated by high cost, lack of insurance coverage, and location accessibility. BH organizations face ongoing challenges to meet the demand for services including costs of operation, worker shortages, and navigating the payer landscape. The history of BH in the U.S. provides the foundation to conceptualize federal regulations and attempts at parity. Literature regarding federal legislation, such as the Mental Health Parity Addiction and Equity Act (MHPAEA), the Affordable Care Act, and Medicaid expansion; BH facilities and …
Development And Validation Of A Theoretically Informed Instrument To Measure The Antecedents Of Microbreaking Intentions (I-Mami) Of Procedural Healthcare Workers, Robin Riddle
ETDs from 2020-2029
ABSTRACT Work-related musculoskeletal disorders (WMSD) affect 77% of nurses and 60% of surgeons, exceeding rates in other occupational sectors and threatening healthcare workforce sustainability. Microbreaking is brief, strategic pause of 20 seconds to five minutes performed every 20 to 40 minutes during medical procedures. It has demonstrated effectiveness in reducing fatigue, improving accuracy, and lowering physiological stress markers without extending medical procedure duration. Despite this evidence, adoption remains limited, and no theoretically informed instruments exist to measure the behavioral determinants of microbreaking intentions among procedural healthcare workers. Investigators of this three-manuscript dissertation developed and established content and construct validity as …
Psychosocial Outcomes In Adults With Cleft Lip And Palate: Exploring The Relationship Between Cleft Severity, Mental Health, And Treatment Satisfaction, Haley Hannabass
Psychosocial Outcomes In Adults With Cleft Lip And Palate: Exploring The Relationship Between Cleft Severity, Mental Health, And Treatment Satisfaction, Haley Hannabass
ETDs from 2020-2029
Introduction:This study aimed to examine psychosocial outcomes in adults with cleft lip and palate (CL/P), focusing on how cleft severity (unilateral versus bilateral) influences depression, anxiety, social functioning, oral health–related quality of life, and satisfaction with treatment outcomes. Individuals born with clefts often continue to face psychosocial challenges even after surgical repair, and limited research has compared how these outcomes differ by cleft type in adulthood. Materials and Methods:A cross-sectional design was used, including 24 adults aged 18 years and older who had undergone cleft repair and were finished or in active orthodontic treatment at UAB. Participants completed an online …
Handling Missing Data In Copd Research, Chia-Ying Chiu
Handling Missing Data In Copd Research, Chia-Ying Chiu
ETDs from 2020-2029
Chronic Obstructive Pulmonary Disease (COPD) remains a major global health concern and one of the leading causes of death in the United States, affecting approximately 4.6% of adults and reaching a prevalence of 9.4% in Alabama according to 2024 National Health Interview Survey. The disease imposes a substantial burden on quality of life and healthcare costs and contributes to increased disability-adjusted life years and years of life lost, as highlighted by the 2022 Lancet Commission report. Despite its im-pact, COPD is frequently diagnosed only after irreversible lung damage has occurred, largely due to under-recognized symptoms and limited diagnostic tools. Early …
Modulation Of The Cgas-Sting Inflammation Pathway In Mouse Models Of Accelerated And Slowed Aging, Benjamin David Heckman
Modulation Of The Cgas-Sting Inflammation Pathway In Mouse Models Of Accelerated And Slowed Aging, Benjamin David Heckman
ETDs from 2020-2029
Chronic sterile inflammation (inflammaging) is a core pillar of aging, and the cGAS-STING innate immune pathway has emerged as a key driver of this process. However, how this pathway intersects with systemic endocrine signaling remains poorly understood. Here, we investigated the intersection of endocrine signaling and cGAS-STING activation using two complementary mouse models with opposing lifespan phenotypes: a short-lived, liver-specific glucagon receptor knockout (LKO) mouse and a long-lived growth hormone-releasing hormone knockout (GHRH-KO) mouse. We demonstrate that despite presenting with a metabolically healthy phenotype, female LKO mice exhibited a significantly reduced lifespan. We link this premature mortality to a sex …
Examining Pain- Related Stigma And Sources Of Resilience In Children With Disorders Of Gut-Brain Interaction, Tolulope Adetayo
Examining Pain- Related Stigma And Sources Of Resilience In Children With Disorders Of Gut-Brain Interaction, Tolulope Adetayo
ETDs from 2020-2029
Background. Painful disorders of gut-brain interaction (DGBI) affect approximately one in five children. In addition to functional impairments, DGBI increase risk for felt stigma (FS) from providers, school personnel, family members, and peers. Children with DGBI may also belong to other minoritized groups that intersect with pain-related FS. However, little is known about how intersectionality impacts the stigma and pain experiences of youth. Further, little is known about the protective capabilities of psychosocial resources (e.g., social support and hope) against FS. Thus, the current study aimed to investigate the impact of FS and its potential moderators in a sample of …
Posterior Cerebellar Lobe Deviations And Social Cognition In Individuals With Psychosis And Their Unaffected Relatives, Andreea Maria Stanica
Posterior Cerebellar Lobe Deviations And Social Cognition In Individuals With Psychosis And Their Unaffected Relatives, Andreea Maria Stanica
ETDs from 2020-2029
Social cognition deficits observed in psychotic disorders contribute to functional impairments. The cerebellum has been identified as a critical brain region involved in social cognitive processes, but the relationship between cerebellar structural deviations and social cognition in individuals with psychosis (probands) and their unaffected relatives remains unclear. Using normative modeling, this study examined cerebellar volume deviations in probands and their unaffected first-degree relatives and investigated associations with social cognitive and motor performance. Probands exhibited significant theory of mind deficits compared to relatives. Probands showed negative deviations in anterior cerebellar lobe relative to the norm, whereas relatives did not. Deviations in …
The Effectiveness Of A Web-Based, Edutainment Intervention On Hiv-Related Stigma, Hiv Knowledge, And Condom Use Self-Efficacy Among Black/African American Emerging Adults, Shirlacia Gray
ETDs from 2020-2029
The Effectiveness of a Web-Based, Edutainment Intervention on HIV-Related Stigma, HIV Knowledge, and Condom Use Self-Efficacy among Black/African American Emerging Adults SHIRLACIA S. GRAY APPLIED DEVELOPMENTAL PSYCHOLOGY ABSTRACT Background: Edutainment interventions were developed to increase knowledge, to influence people’s attitudes and behaviors toward sexual, social and public health issues, and to promote behavior change. This current study implemented an edutainment intervention to examine its effectiveness on increasing HIV knowledge, reducing HIV-related stigma, and increasing condom use self-efficacy among Black/African American Emerging Adults in Birmingham, AL. Methods: This current study used longitudinal data from the City Health-II intervention for secondary data …
Exploring Criminality Through A Developmental Lens: Contextual Effects From Childhood To Emerging Adulthood, Abigail Jeanette Anderson
Exploring Criminality Through A Developmental Lens: Contextual Effects From Childhood To Emerging Adulthood, Abigail Jeanette Anderson
ETDs from 2020-2029
Adolescent delinquency is a key predictor of later criminal behaviors and is associated with negative outcomes across education, employment, and health. Despite extensive research, gaps remain regarding the interplay of individual- and context-level factors in the development of delinquency, as well as the reliance on cross-sectional or retrospective designs. Guided by a social-ecological framework, the present dissertation examines how family, school, and neighborhood contexts interact with individual behaviors to shape pathways toward delinquency and adult criminality across childhood, adolescence, and early adulthood. The first study investigated the cascading effects of paternal engagement, parental aggravation, and early child behavior problems in …
Amino Acid Pet Tracers For Cancer Imaging And Response Assessment, Ugur Akca
Amino Acid Pet Tracers For Cancer Imaging And Response Assessment, Ugur Akca
ETDs from 2020-2029
Triple-negative breast cancer (TNBC) and high-grade glioma (HGG) pose significant diagnostic and therapeutic challenges due to their aggressive biology and the limitations of [¹⁸F]FDG PET, which suffers from nonspecific uptake in inflammatory tissues, complicating differentiation of viable tumor from treatment-related effects. Computed Tomography, while strong for structural changes, has limited soft tissue contrast for distinguishing tumor from inflammation, and Magnetic Resonance Imaging, despite superior soft tissue resolution, struggles with differentiating active tumor from post-treatment changes like edema or necrosis due to nonspecific enhancement. These challenges highlight the necessity for complementary and advanced imaging strategies for improved diagnosis and monitoring. This …
Bidirectional Effects Of Transcutaneous Auricular Vagus Nerve Stimulation On Insomnia And Brain Health In Breast Cancer, Melissa Van Trang Do
Bidirectional Effects Of Transcutaneous Auricular Vagus Nerve Stimulation On Insomnia And Brain Health In Breast Cancer, Melissa Van Trang Do
ETDs from 2020-2029
Breast cancer remains the most frequently diagnosed cancer among women worldwide, with over 2.3 million new cases annually. While advances in treatment have improved survival, many women continue to suffer from persistent insomnia, fatigue, anxiety, depression, and cognitive dysfunction that collectively impair quality of life and recovery. These interrelated symptoms share common biological underpinnings, including autonomic dysregulation, vagal withdrawal, and chronic inflammation. Transcutaneous auricular vagus nerve stimulation (taVNS) is a non-invasive, bioelectronic therapy that modulates afferent vagal pathways via auricular branches of the vagus and trigeminal nerves. By engaging central autonomic and neuroimmune circuits, including the nucleus tractus solitarius and …
Sample Preparation Effects On Liquid Scintillation Counting Quench, Jason Rusch
Sample Preparation Effects On Liquid Scintillation Counting Quench, Jason Rusch
ETDs from 2020-2029
Liquid Scintillation Counting (LSC) is a critical technique in operational health physics, particularly for contamination surveys. However, common, expedient sample preparation choices often introduce unpredictable levels of quench, compromising the accuracy of results. This thesis investigates the impact of common preparation variables including vial material, cap lining, solid sample matrix presence, cocktail volume, and radioactivity. The impact of these sample preparation variables were evaluated using the quench methods on two fundamentally distinct commercial LSC systems, the Perkin Elmer Tri-Carb 4910TR (employing tSIE correction) and the Hidex 600 SL (employing TDCR correction). A total of 320 samples were evaluated on each …