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Articles 151 - 180 of 1791685
Full-Text Articles in Entire DC Network
Restorative Environments And Therapeutic Artmaking: A Strengths-Based Art Gallery Workshop To Enhance Well-Being In Emerging Adults, Jeannine Case
Restorative Environments And Therapeutic Artmaking: A Strengths-Based Art Gallery Workshop To Enhance Well-Being In Emerging Adults, Jeannine Case
Art Therapy | Master's Theses
Emerging adults aged 18 to 29 face increased mental health risks yet encounter considerable barriers to traditional care, which highlights the need for accessible, preventive alternatives. This mixed-methods pilot study investigated whether an art gallery environment could serve as a supportive setting for a strengths-based, positive art therapy-informed wellness workshop aimed at promoting well-being for this population. Six participants between the ages of 20 and 27, all enrolled in post-secondary education, took part in this study. Five identified as female and one as male. Three participants (50%) identified as Hispanic/Latino, one as Asian, one as White, and one as Hispanic/Latino …
How Traditional And Social Media Shapes Public Perception Of United States Surpeme Court Decisions On Civil Liberties, Leila P. Martin
How Traditional And Social Media Shapes Public Perception Of United States Surpeme Court Decisions On Civil Liberties, Leila P. Martin
Williams Honors College, Honors Research Projects
This study examines how traditional and social medai shape public perception of U.S. Supreme Court decisions on Civil liberties, focusing on four landmark cases: Dobbs v. Jackson, District of Columbia v. Heller, Materpiece Cakeshop v. Colorado Civil Rights Commission, and Obergfell v. Hodges. Using Entmans framing theory, the research analyzes how tone, language, emphasis, and ideological slant differ across media platofrms and how these frames infleunce public attitudes, insitutional trust, and civic understanding. A mixed-methods design combines archival media analysis, national polling data from Pew Rsearch Center and gallup, and an independent survery to asses how media narratives, rather than …
Effects Of Varying Biochar Concentrations On The Growth Of Lactuca Sativa (Newham Bibb Lettuce), Lauren Holler
Effects Of Varying Biochar Concentrations On The Growth Of Lactuca Sativa (Newham Bibb Lettuce), Lauren Holler
Williams Honors College, Honors Research Projects
The objective of this research experiment was to investigate the effectiveness of using biochar in potting soil in terms of plant growth and soil quality. This experiment was carried out using varying amounts (0%, 5%, 10%, and 20%) of biochar in the soil to see its effect on seed germination, plant growth, and soil quality such as pH, water retention, and soil temperature. The aim of the experiment was to identify whether biochar can be used in soil to promote healthier and stronger plants. There were four treatments which included 0% (Control), 5% (Treatment 1), 10% (Treatment 2), and 20% …
The Impact Of Mindfulness-Based Relapse Prevention In Rolling-Admission Format On Mental Health Outcomes Of Adults In Residential Treatment For Opioid Use Disorder, Alice Laughlin
West Chester University Graduate Theses, Dissertations, and Final Projects
Opioid use disorder is associated with serious psychological, social, and public health consequences. Co-occurring mental health difficulties further complicate recovery, underscoring the need for interventions that address psychological well-being alongside substance use. This study examined the impact of Mindfulness-Based Relapse Prevention adapted for rolling admission (MBRP-RA) on trait mindfulness, global mental health, and abstinence self-efficacy among adults in residential treatment for opioid use disorder. Participants were randomly assigned to adjunctive MBRP-RA plus treatment as usual (MBRP+TAU) or treatment as usual (TAU) only. Two-way mixed analyses of variance indicated significant treatment condition × time point interactions for trait mindfulness and global …
Bee Positive Missoula, Sophia Mahoney, Mckenna Hill, Olivia Cornwell, Lucas Hardoerfer, Brandon Quamme
Bee Positive Missoula, Sophia Mahoney, Mckenna Hill, Olivia Cornwell, Lucas Hardoerfer, Brandon Quamme
Undergraduate Theses, Professional Papers, and Capstone Artifacts
Bees are an essential species that support the growth of plant communities and enhance human agricultural success. Urbanization is associated with increased impermeable surfaces, large-scale land-use change, and changes in plant and animal community assemblages. Urban expansion exacerbates habitat fragmentation and loss, which has a particularly negative impact on wild or native specialist bee pollinators and the plant species they pollinate. Global and local research indicate the widespread nature of these negative trends; however, there are abundant opportunities to mitigate the impacts on bee pollinators by restoring wild bee habitat in urban areas. Habitat includes nesting and floral resources, and …
The Impact Of Virtual Discharge Interventions Compared To Traditional Methods On Adult Patient Population Readmission Rates: An Integrative Review, Tiffany Providence, Carrie Brooks, Nannono Kayondo, Courteney Lovell, Alice Smith
The Impact Of Virtual Discharge Interventions Compared To Traditional Methods On Adult Patient Population Readmission Rates: An Integrative Review, Tiffany Providence, Carrie Brooks, Nannono Kayondo, Courteney Lovell, Alice Smith
Master's Projects
Hospital readmissions are a persistent quality and cost burden to the healthcare system, prompting evaluation of modern strategies to strengthen transitional care. This integrative review synthesized findings from thirteen studies published between 2011 and 2025 to assess the effectiveness of virtual discharge interventions in reducing readmission rates among adult patients. Virtual discharge interventions included programs utilizing technology, such as phone calls, video visits, apps, or remote monitoring, to help patients understand their care and improve positive outcomes. Many of these studies showed that virtual support can reduce hospital readmissions, especially for people with heart failure. Some programs also improved patients’ …
The Relation Between Stress, Self-Esteem, University Belongingness, And Disciplinary History In Undergraduate Students, Emily R. Brown
The Relation Between Stress, Self-Esteem, University Belongingness, And Disciplinary History In Undergraduate Students, Emily R. Brown
West Chester University Graduate Theses, Dissertations, and Final Projects
This study examined the relation between student conduct history and psychosocial characteristics, including university belongingness, perceived stress, and self-esteem, among undergraduate students at West Chester University. A total of 392 students ages 18–25 completed self-report measures via Qualtrics, including the University Belongingness Questionnaire (UBQ), the Perceived Stress Scale (PSS-14), and the Rosenberg Self-Esteem Scale (RSES). Participants were recruited through the SONA system and in collaboration with the Office of Student Conduct to include students with and without a documented conduct record. Results from independent samples t-tests indicated that students with a conduct record reported significantly higher levels of university belongingness …
Supporting Bibliodiversity And Access Through Library Resource Sharing, J. Silvia Cho
Supporting Bibliodiversity And Access Through Library Resource Sharing, J. Silvia Cho
Publications and Research
Librarians, with their core values of access, intellectual freedom, stewardship and democracy, share bibliodiversity advocates’ vision of an eco-social system of diverse cultures and reading as a democratic and emancipatory practice. Librarians bolster bibliodiversity by collecting inclusively, critically reviewing and decolonizing library collections, and centering access. Building on previous discussions on the role of open access in strengthening bibliodiversity, this paper acknowledges and articulates how interlibrary loan and library resource sharing also support bibliodiversity. Doing so is important to augment advocacy and support for these services. Advancing solutions to challenges in resource sharing means also advancing towards bibliodiversity goals, supporting …
Sporadic Creutzfeldt-Jakob Disease: A Case Report Of Rapidly Progressive Dementia, Diane Olski, Karissa Charles, Cristin Grant, Courtnee Harpine, Shannon Leonard, Sarah Puim
Sporadic Creutzfeldt-Jakob Disease: A Case Report Of Rapidly Progressive Dementia, Diane Olski, Karissa Charles, Cristin Grant, Courtnee Harpine, Shannon Leonard, Sarah Puim
South Atlantic Division GME Research Day 2025
No abstract provided.
Breaking The Silence: Investigating The Impact Of Stigma On Help-Seeking Behaviors Among Adults With A History Of Adverse Childhood Experiences In Ghana, Deborah Amoako-Atta
Breaking The Silence: Investigating The Impact Of Stigma On Help-Seeking Behaviors Among Adults With A History Of Adverse Childhood Experiences In Ghana, Deborah Amoako-Atta
West Chester University Graduate Theses, Dissertations, and Final Projects
In Ghana, cultural beliefs often silence open discussion about mental health. Many view emotional struggles as spiritual weakness, leading to stigma and avoidance of care. For adults who experienced Adverse Childhood Experiences (ACEs), this silence can worsen the long-term impact of trauma. While Western research links stigma to reduced help-seeking and shows that trauma knowledge can promote openness, little is known about how these relationships function within Ghana’s cultural context. This cross-sectional study examined how stigma and trauma knowledge influence help-seeking behaviors among 103 Ghanaian adults (ages 19-62, M = 30.0; 49% women) with childhood adversity histories. Participants completed anonymous …
Grievability Of The Abject As Narrated By Exiles, Sylvia Azmy
Grievability Of The Abject As Narrated By Exiles, Sylvia Azmy
Theses and Dissertations
This thesis analyzes two novels: Inaam Kachachi’s Sawaqi al-Qulub (2005) and Shady Lewis’s ʿAla Khatt Grinitsh (2019), to understand the relationships between figures of migration, as the exile narrates his encounters with refugees. It uses Julia Kristeva’s Powers of Horror: An Essay on Abjection (1980) and Judith Butler’s Frames of War: When Is Life Grievable? (2009) as theoretical frameworks to examine the deaths of refugees and their corpses (utmost of abjection) in the two novels. Scholars have argued that the literature of forced migration is becoming more inclusive than migration narratives, a term that has focused on student travelers, exilic …
Southern Adventist University Undergraduate Catalog 2026-2027, Southern Adventist University
Southern Adventist University Undergraduate Catalog 2026-2027, Southern Adventist University
Catalog, Undergraduate
Southern Adventist University's undergraduate catalog for the academic year 2026-2027.
Southern Adventist University Graduate Catalog 2026-2027, Southern Adventist University
Southern Adventist University Graduate Catalog 2026-2027, Southern Adventist University
Catalog, Graduate
Southern Adventist University's graduate catalog for the academic year 2026-2027.
The Moderating Role Of Perceived Resource Abundance In The Links Between Self-Compassion, Self-Coldness, Coping Strategies, And Mental Health, Evan E. Ozmat
Electronic Theses & Dissertations (2024 - present)
Undergraduate students increasingly present to college counseling centers with pre-existing mental health concerns, including depression and suicidal ideation, emphasizing the urgent need for effective interventions and a deeper understanding of contributing factors. Self-compassion—responding kindly to oneself amid suffering—and its theorized counterpart, self-coldness—characterized by self-judgment and isolation—have emerged as key constructs influencing mental health. The two-factor model of self-compassion, grounded in Gilbert’s (2005a) Theory of Social Mentalities (TSM), posits that self-compassion and self-coldness are distinct unipolar continua shaped by evolved safeness and threat-defense systems that regulate social behaviors and mental health outcomes. The present study examines the mediating role of prosocial …
An Assessment Of Carbon Dioxide Removal Potential From Stormwater Ponds Using Concrete-Based Materials, Yu-Hsuan Tai
An Assessment Of Carbon Dioxide Removal Potential From Stormwater Ponds Using Concrete-Based Materials, Yu-Hsuan Tai
Theses and Dissertations (Comprehensive)
Stormwater ponds (SWPs) are engineered stormwater infrastructure known to be major greenhouse gas (GHG) emitters, including carbon dioxide (CO2). Concrete-based materials have great potential to capture CO2 as carbonate minerals (CaCO3), through aqueous carbonation, driven by their alkaline nature and high portlandite (Ca(OH)2) content. However, the mechanistic understanding of how specific parameters including mass, surface area, and degradation of calcium silicate hydrate (C-S-H) phases collectively control carbonation kinetics and CO2 uptake under dynamically evolving conditions remains underexplored. Laboratory-scale experiments were conducted to evaluate the effects of cement dosage, particle surface area, and …
Push-Pull Farming System Helps Insure Smallholder Maize Production Under Climate Change, Yann Clough, Wilhelm May, Timothy Luttermoser, Dickens Nyagol, Nikolaos Alexandridis, Frank Chidawanyika, Mattias Jonsson, Charles A.O. Midega, Katja Poveda, Zeyaur R. Khan
Push-Pull Farming System Helps Insure Smallholder Maize Production Under Climate Change, Yann Clough, Wilhelm May, Timothy Luttermoser, Dickens Nyagol, Nikolaos Alexandridis, Frank Chidawanyika, Mattias Jonsson, Charles A.O. Midega, Katja Poveda, Zeyaur R. Khan
All Peer-Reviewed Publications
Agroecological approaches harnessing in-field biodiversity have been highlighted as a sustainable way to reduce yield gaps, but long-term assessments of their ability to buffer production from weather extremes and increasing interannual and intraseasonal climate variability are scarce. Here, we analyze a 12-year dataset from 642 control vs. push-pull maize field pairs in western Kenya, where long-term climate trends include increasing temperatures and intensifying drought and rainfall. In push-pull, maize is intercropped with a fodder legume that improves soil fertility, suppresses weeds, and deters pests, and is bordered with fodder grasses attracting and suppressing the pests. We assess interactions between push-pull …
Find My Friends: Investigating Peer Direction In The Degu Retrosplenial Cortex, Angela T.N. Le
Find My Friends: Investigating Peer Direction In The Degu Retrosplenial Cortex, Angela T.N. Le
Theses and Dissertations (Comprehensive)
In most species, social interaction depends on spatial proximity and the dynamics of approach can signal intention. While representations of others’ spatial locations have been found in areas like the hippocampus, we still have a limited understanding of how the brain uses these to guide social movement. The retrosplenial cortex (RSC) integrates spatial information from both hippocampus and posterior parietal cortex and may help link this information with motor control systems. We recorded neuron activity from the RSC of degus while they freely interacted with one or two peers. Similar to other species, we identified a robust population of head-direction …
Endogenous Light In The Brain: Investigating Sources, Propagation, And State-Dependent Emission, Emre Cicek
Endogenous Light In The Brain: Investigating Sources, Propagation, And State-Dependent Emission, Emre Cicek
Theses and Dissertations (Comprehensive)
Ultraweak photon emission (UPE), and by extension light, has long been thought to be a modality of communication in nature. Prior studies have already identified that UPE can depend on cell type and can be used to discern between malignant and benign cells. However, besides theoretical models, not much effort has been made to identify possible biological structures that would allow for light to be used as a method of communication in the human body. According to the framework set by Shannon’s Information Theory, for communication to be possible at minimum a transmitter, a transmission channel, and a receiver are …
Optimizing Human Fcrn Mouse Models To Improve Pharmacokinetic Evaluation Of Antibody Drug Candidates., Gregory J. Christianson, Zachary M Howard, Samantha Kenney, Emily Lowell, Nijaguna Bethur, Derry C. Roopenian, Elena Gonzalo-Gil
Optimizing Human Fcrn Mouse Models To Improve Pharmacokinetic Evaluation Of Antibody Drug Candidates., Gregory J. Christianson, Zachary M Howard, Samantha Kenney, Emily Lowell, Nijaguna Bethur, Derry C. Roopenian, Elena Gonzalo-Gil
Faculty Research 2026
The use of animal models that can reliably predict drug performance in human patients is critical to antibody therapeutic development. Along with assessing toxicity and efficacy, determining the pharmacokinetic (PK) properties of therapeutics in Tg32 and Tg276 mice is essential to preclinical characterization. While Tg32 mice have been well established as indispensable in their ability to model the PK properties of antibody therapeutics, their intact immunity leaves them capable of mounting anti-drug antibody responses that interfere with PK interpretation. Here, we demonstrate the negative impact anti-drug responses can have on PK parameters derived from Tg32 mice, and provide strong evidence …
Optimizing Human Fcrn Mouse Models To Improve Pharmacokinetic Evaluation Of Antibody Drug Candidates., Gregory J. Christianson, Zachary M Howard, Samantha Kenney, Emily Lowell, Nijaguna Bethur, Derry C. Roopenian, Elena Gonzalo-Gil
Optimizing Human Fcrn Mouse Models To Improve Pharmacokinetic Evaluation Of Antibody Drug Candidates., Gregory J. Christianson, Zachary M Howard, Samantha Kenney, Emily Lowell, Nijaguna Bethur, Derry C. Roopenian, Elena Gonzalo-Gil
Faculty Research 2026
The use of animal models that can reliably predict drug performance in human patients is critical to antibody therapeutic development. Along with assessing toxicity and efficacy, determining the pharmacokinetic (PK) properties of therapeutics in Tg32 and Tg276 mice is essential to preclinical characterization. While Tg32 mice have been well established as indispensable in their ability to model the PK properties of antibody therapeutics, their intact immunity leaves them capable of mounting anti-drug antibody responses that interfere with PK interpretation. Here, we demonstrate the negative impact anti-drug responses can have on PK parameters derived from Tg32 mice, and provide strong evidence …
Trends In The Utilization Of Metaverse Technology In Media Content Production:A Second-Level Study Of The Arab Experience, Amal Nabil Badr, Tarek Ismail Mohamed, Nassereldin Abdel Qadir Osman
Trends In The Utilization Of Metaverse Technology In Media Content Production:A Second-Level Study Of The Arab Experience, Amal Nabil Badr, Tarek Ismail Mohamed, Nassereldin Abdel Qadir Osman
Journal of Arts and Social Sciences
The research problem is defined through a main question: How did Arab studies discuss the interactions of the Arab media experience with metaverse technology and supporting tools, the limits and levels of current and future use of this technology in Arab media institutions, and how did the quantitative and qualitative trends in these studies reflect the applied aspect in using metaverse technology and related tools in media content industry? The research relies on the secondary analysis methodology of the results reached by studies that dealt with the analysis of A sample of (30 studies) from 2015 until 2023. The results …
Study On The Concept And Framework Of Synergy Between Mitigation And Adaptation, Xianchun Tan
Study On The Concept And Framework Of Synergy Between Mitigation And Adaptation, Xianchun Tan
Double Helix Methodology
Carbon neutrality and the Global Goal on Adaptation jointly drive the integration of mitigation and adaptation; however, a clear conceptual and analytical framework for their synergy remains absent. This study first examines the components of mitigation and adaptation, and analyzes the mechanisms through which they interact. It then explores the fundamental principles underlying the synergy between mitigation and adaptation, and construct a corresponding analytical framework. It emphasizes that mitigation and adaptation are mutually influential, providing a foundation for achieving synergy. Furthermore, synergy should be promoted in the five aspects of objectives, regions, sectors, pathways, and policies—and follows the logic of …
Diagnostic Delays In Endometriosis Among Reproductive-Aged Women: An Evidence-Based Primary Care Policy Proposal, Francis P. Ronayne
Diagnostic Delays In Endometriosis Among Reproductive-Aged Women: An Evidence-Based Primary Care Policy Proposal, Francis P. Ronayne
Capstones
No abstract provided.
Using Randomization To Compare Ai And Expert-Generated Formative Assessment Questions In Medical Education, Akshat Kumar, Katie Stinson, Litao Wang, Elizabeth Nugent, Yongsu Lee, Mark Hormann, Latanya Jones Love, Toufeeq Ahmed Syed
Using Randomization To Compare Ai And Expert-Generated Formative Assessment Questions In Medical Education, Akshat Kumar, Katie Stinson, Litao Wang, Elizabeth Nugent, Yongsu Lee, Mark Hormann, Latanya Jones Love, Toufeeq Ahmed Syed
Faculty, Staff and Student Publications
Background: AI-generated content is being used across the education spectrum and is beneficial for creating complex multiple-choice questions, such as those used in medical education. However, evaluating AI-generated content is challenging, and existing testing and evaluation methods are falling short. This study uses randomization to compare medical students' performance on and subjective evaluation of AI versus expert-generated questions. We hypothesized that there would be no difference in student performance or subjective evaluation of AI vs expert-generated questions.
Methods: We designed a single-center, randomized study where medical student participants received either one AI- or expert-generated question per day over four weeks. …
Sustainable – Low-Cost - Upgrade Of Activated Sludge Process For Nitrogen And Phosphorus (N&P) Removal From Wastewater, Abanoub N. Basta
Sustainable – Low-Cost - Upgrade Of Activated Sludge Process For Nitrogen And Phosphorus (N&P) Removal From Wastewater, Abanoub N. Basta
Theses and Dissertations
Many municipal wastewater treatment plants (WWTPs) in developing countries were designed primarily for organic matter and suspended solids removal and therefore face increasing difficulty in meeting modern nitrogen (N) and phosphorus (P) discharge requirements. Conventional biological nutrient removal upgrades commonly require additional reactor volume, recirculation systems, aeration energy, and capital investment. Accordingly, sustainable retrofit strategies that improve nutrient removal within existing treatment footprints are increasingly needed, particularly in water-scarce and land-constrained regions.
This study investigated the integration of water hyacinth (Eichhornia crassipes) into the aeration stage of an activated sludge process as a hybrid nature-based enhancement for nitrogen and phosphorus …
A Comparative Study: Force Majeure And The Theory Of Unforeseen Circumstances Across Different Jurisdictions In The Middle East, Omar Hamed Sawan
A Comparative Study: Force Majeure And The Theory Of Unforeseen Circumstances Across Different Jurisdictions In The Middle East, Omar Hamed Sawan
Theses and Dissertations
The motivation behind this study stems from recent global disruption events that impact construction projects worldwide. These events vary across a wide spectrum, whether they are political events such as the Russo-Ukraine war or the war in the Middle East, economic events such as inflation or currency devaluations; or environmental events such as climate change and the emergence of public health crises like the Covid-19 pandemic. These series of events underscore the growing importance of understanding how the different legal frameworks address unforeseeable events in the construction industry. In this context, force majeure and the theory of unforeseen circumstances (also …
Diet Quality As Assessed By The Healthy Eating Index-2020 Among Individuals Diagnosed With And Without Type 2 Diabetes, Minghao Zhou, Hairui Yu, Renee Underwood, Hongning Cai, Tung Sung Tseng, Susu Luo
Diet Quality As Assessed By The Healthy Eating Index-2020 Among Individuals Diagnosed With And Without Type 2 Diabetes, Minghao Zhou, Hairui Yu, Renee Underwood, Hongning Cai, Tung Sung Tseng, Susu Luo
School of Public Health Faculty Publications
Background: Dietary management is key to preventing and controlling type 2 diabetes mellitus (T2DM). However, few studies have examined differences in Healthy Eating Index (HEI-2020) scores and components among individuals with and without diagnosed T2DM. This study aimed to assess gender differences in HEI-2020 scores and its 13 components by T2DM status. Methods: Using National Health and Nutrition Examination Survey (NHANES) data from 2011 to 2018, this cross-sectional study analyzed 19,464 adults. Diagnosed T2DM was identified via self-report or diabetes medication use. Diet quality was assessed using the HEI-2020, scored from 0 to 100, with a higher HEI score indicates …
Steroid Receptor Coactivator 3-Deficient Regulatory T Cells Eradicate Multiple Solid Tumors In Syngeneic Mouse Models, Nuri Sung, Eunsu Kim, Yosef Gilad, Yuri Park, Adam M Dean, Yan Xia, Jianming Xu, Clifford C Dacso, David M Lonard, Sang Jun Han
Steroid Receptor Coactivator 3-Deficient Regulatory T Cells Eradicate Multiple Solid Tumors In Syngeneic Mouse Models, Nuri Sung, Eunsu Kim, Yosef Gilad, Yuri Park, Adam M Dean, Yan Xia, Jianming Xu, Clifford C Dacso, David M Lonard, Sang Jun Han
Faculty, Staff and Students Publications
Steroid receptor coactivator 3 (SRC-3) is highly expressed in regulatory T cells (Tregs) and is important for their immunosuppressive activity. Recently, we demonstrated that disrupting SRC-3 expression in Tregs eliminates triple-negative breast cancer (TNBC) and prostate cancer in syngeneic animal models by generating an anti-tumor immune microenvironment without inducing immune-related adverse events (irAEs). Further analysis of these mice revealed that SRC-3 knockout (KO) Tregs infiltrated breast tumors and facilitated the infiltration of CD8
When Probiotics Guidelines Differ: A Practical Guide For Clinicians And Researchers, Geoffrey A Preidis, Hania Szajewska, Marla Cunningham, Howard Bauchner, Daniel J Merenstein
When Probiotics Guidelines Differ: A Practical Guide For Clinicians And Researchers, Geoffrey A Preidis, Hania Szajewska, Marla Cunningham, Howard Bauchner, Daniel J Merenstein
Faculty, Staff and Students Publications
Many professional organizations publish clinical practice guidelines for the use of probiotics in gastrointestinal disorders. Generally, no two guidelines align perfectly, and some differ markedly. These discrepancies occur because clinical practice guidelines are not purely mechanical outputs of data synthesis. They are shaped by structured interpretation, value judgments, and predefined thresholds for uncertainty. These elements become particularly visible when effect sizes are small, heterogeneity is high, and outcomes vary in clinical relevance-as is the case with probiotic research. This article examines why discordance among probiotic guidelines is predictable and provides practical guidance for clinicians who must decide among conflicting recommendations …
Limosilactobacillus Reuteri Promotes Melatonin Release From Human Intestinal Organoids Via 5′Ectonucleotidase Activity, Micah D Forshee, Erika J Nachman, Esha R Shenoy, Heather A Danhof, Ludwig Ermann Lundberg, Stefan Roos, Robert A Britton
Limosilactobacillus Reuteri Promotes Melatonin Release From Human Intestinal Organoids Via 5′Ectonucleotidase Activity, Micah D Forshee, Erika J Nachman, Esha R Shenoy, Heather A Danhof, Ludwig Ermann Lundberg, Stefan Roos, Robert A Britton
Faculty, Staff and Students Publications
Strains of Limosilactobacillus reuteri have been used to prevent or treat various conditions; however, the mechanisms by which they exert beneficial effects are not completely understood. Infant colic is one example in which L. reuteri DSM 17938 reduces clinical symptoms. While the etiology of colic is unknown, abnormal melatonin levels in infants have been suggested as a possible contributor. L. reuteri DSM 17938 has been shown to produce adenosine from AMP via production of the extracellular enzyme 5′ectonucleotidase (5′NT). Adenosine is a potent signaling molecule that impacts several important aspects of host physiology, including the release of melatonin from the …