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Full-Text Articles in Entire DC Network
Electromechanical Mapping Of The In Vivo Porcine Heart And Stomach, Haley Nesmith Patton
Electromechanical Mapping Of The In Vivo Porcine Heart And Stomach, Haley Nesmith Patton
All ETDs from UAB
Electrical excitation and mechanical function are integral to the physiologic activity of both the heart and stomach. Electrical depolarization through the myocardium triggers contraction in the heart. When normal sequences of electrical activity are disturbed, the heart’s mechanical function may also be disturbed, affecting its ability to pump blood effectively, sometimes fatally. Similarly, electrical waves called slow waves initiate gastric peristalsis. Abnormalities in slow wave propagation patterns can disturb the stomach’s ability to mechanically process gastric contents, sometimes resulting in delayed gastric emptying, nausea, and vomiting. The relationship between mechanical function and electrophysiology is not unidirectional, though. Mechanical stimuli can …
The Role Of Fibroblast Growth Factor Receptors In Inflammatory Airway Diseases, Molly Easter
The Role Of Fibroblast Growth Factor Receptors In Inflammatory Airway Diseases, Molly Easter
All ETDs from UAB
Chronic inflammation plays a role in the development and progression of airway diseases such as chronic obstructive pulmonary disease (COPD) and cystic fibrosis (CF). COPD is caused primarily by chronic cigarette smoke exposure. Conversely, CF is a single gene disorder caused by mutations in the cystic fibrosis transmembrane conductance regulator gene (CFTR). Although the causes of COPD and CF are different, there are common pathological features. Studies show that chronic inflammation plays a significant role in the pathogenesis of both COPD and CF. Moreover, chronic inflammation induces ageing-associated pathomechanisms like cellular senescence, which exacerbates chronic inflammation. Previous work demonstrates that …
Genotype And Sex Specific Effects Of Methionine Restriction On The Life And Healthspan Of Drosophila Melanogaster, Joshua Robert Smith
Genotype And Sex Specific Effects Of Methionine Restriction On The Life And Healthspan Of Drosophila Melanogaster, Joshua Robert Smith
All ETDs from UAB
Reduced dietary intake of the amino acid methionine has been reported to significantly extend the lifespan of common laboratory model organisms including Saccharomyces cerevisiae, Mus musculus, and Drosophila melanogaster. Methionine restriction (MR) has also been achieved via non-dietary means such as metabolite supplementation and CRISPR-Cas9 gene editing. MR along with protein and calorie restriction are known as dietary interventions capable of producing pro-longevity benefits through regulation of nutrient sensing pathways. Recent studies in model organisms have also identified beneficial effects of a low methionine diet on aging-associated phenotypes and markers of overall healthspan. However, the effects of this intervention on …
Characterizing The Reproductive System Of Avrainvillea In HawaiʻI, Brinkley Mikayla Thornton
Characterizing The Reproductive System Of Avrainvillea In HawaiʻI, Brinkley Mikayla Thornton
All ETDs from UAB
Sex has generated incredible life cycle diversity across eukaryotes. Differences in the timing of meiosis and fertilization have generated tremendous variation in the duration of haploid and diploid phases. To understand what drives eukaryotic sexual diversity, there remains a need to determine the rates of sexual and asexual reproduction in natural populations. Moreover, life cycle diversity is predicted to be correlated with the reproductive system. Yet, most studies on reproductive variation have focused on diploid or diploid dominant organisms, hindering the ability to understand sex. Macroalgae can serve as useful models to overcome this limitation via life cycle and reproductive …
The Impact Of O-Glcnac Signaling On Dna Hydroxymethylation In Temporal Lobe Epilepsy, Rudhab Bahabry
The Impact Of O-Glcnac Signaling On Dna Hydroxymethylation In Temporal Lobe Epilepsy, Rudhab Bahabry
All ETDs from UAB
Temporal Lobe Epilepsy (TLE) is the most prevalent form of focal epilepsy and the most treatment-resistant type. This condition is characterized by recurrent, unprovoked seizures typically originating in the hippocampus. Epigenetic modifications such as DNAme changes have been implicated in brain functions such as synaptic plasticity, learning and, memory, and cognition. The oxidation of DNA 5-methylcytosine (5-mC) and its oxidized form, 5-hydroxymethylcytosine (5-hmC) catalyzed by Ten-Eleven Translocation (TET) family of dioxygenases and linked to epilepsy's hyperexcitable state. Post‐translational modifications (PTMs) of proteins, such as O-GlcNAcylation, facilitate cells' immediate responses to intracellular or extracellular environmental stimuli by modifying the functions of …
"Decidedly Good Looking:" Horatio Alger’S Juvenile Heroes And The Racial Subtext Of The American Dream, Madison Robin Owens
"Decidedly Good Looking:" Horatio Alger’S Juvenile Heroes And The Racial Subtext Of The American Dream, Madison Robin Owens
All ETDs from UAB
No abstract provided.
Evaluation Of Feed Intake, Growth, And Reproduction In The Zebrafish, Danio Rerio, Fed A Gel-Based Diet, Thomas Logan Holfelder
Evaluation Of Feed Intake, Growth, And Reproduction In The Zebrafish, Danio Rerio, Fed A Gel-Based Diet, Thomas Logan Holfelder
All ETDs from UAB
EVALUATION OF FEED INTAKE, GROWTH, AND REPRODUCTION IN THE ZEBRAFISH, DANIO RERIO, FED A GEL-BASED DIET THOMAS LOGAN HOLFELDER BIOLOGY ABSTRACT The zebrafish, Danio rerio, is a valuable pre-clinical model, aiding human health understanding and translational aquaculture. Comprehensive documentation of the culture of this model exists, with ongoing efforts to optimize husbandry requirements, particularly in the areas of diet and nutrition. Labor or mechanical costs related to feeding are high in most laboratories and alternative protocols to reduce feed handling would be beneficial and could allow the capability to monitor feed consumption. A commercially produced gel-based diet has a high …
Cultural Connectedness And Native American Mental Health, Sharyn Washburn Hillin
Cultural Connectedness And Native American Mental Health, Sharyn Washburn Hillin
All ETDs from UAB
CULTURAL CONNECTEDNESS AND NATIVE AMERICAN MENTAL HEALTH SHARYN W. HILLIN EDUCATIONAL STUDIES IN DIVERSE POPULATIONS ABSTRACT Recent research has indicated a possible connection between the destruction of Native American culture and communities and mental health disparities among Native Americans in the United States. While numerous studies have been conducted among Native Americans in western regions of the United States that establish a relationship between cultural connectedness and mental health resiliency, no such relationship has been investigated in the southeastern region of the United States, particularly within the state of Alabama. Using a blended ethnographic phenomenological methodology, ten Poarch-Creek Indians in …
The Freshman Life And Student Health (Flash) Study: Using Social Network Analysis To Understand How Obesity And Stigma Impact Emerging Adult Health, Alena C. Borgatti
The Freshman Life And Student Health (Flash) Study: Using Social Network Analysis To Understand How Obesity And Stigma Impact Emerging Adult Health, Alena C. Borgatti
All ETDs from UAB
Both racial discrimination and weight stigma have been identified as risk factors for poorer mental, physical, and social health. College students are vulnerable to the effects of stigma, as they greatly value peer acceptance and friendships during a pivotal time of emotional and health behavior development. The present study was the first to use social network analysis to examine the impact of weight and racial discrimination on the development of college social relationships and how these experiences influence students’ physical and mental health. 1330 participants (69% of on-campus freshmen) completed a brief survey on social networks, physical health, mental health, …
Inquiro 12 (Complete Issue), Inquiro Staff
Inquiro 12 (Complete Issue), Inquiro Staff
Inquiro (undergraduate research journal)
https://www.uab.edu/inquiro/issues/current-issue
Antineutrophilic Cytoplasmic Antibody (Anca) Positive Vasculitis In An Elderly Male, Peter Abdelmessih, Oseyime Okoeguale, Blake Bauer, John Fanning
Antineutrophilic Cytoplasmic Antibody (Anca) Positive Vasculitis In An Elderly Male, Peter Abdelmessih, Oseyime Okoeguale, Blake Bauer, John Fanning
UAB Huntsville Research Day - All Presentations
2024 clinical vignette poster
Massive Splenomegaly Revealing Long-Neglected Essential Thrombocythemia: A Case Report, Pierce Elliott, Timothy Pham, Pranayraj Kondapally, Hinal Rathi, Alan Baggett
Massive Splenomegaly Revealing Long-Neglected Essential Thrombocythemia: A Case Report, Pierce Elliott, Timothy Pham, Pranayraj Kondapally, Hinal Rathi, Alan Baggett
UAB Huntsville Research Day - All Presentations
2024 clinical vignette poster
Investigating Hiv-1 Transmission To Human Cervix Using Reporter Virus Technologies, Dana Frances Indihar
Investigating Hiv-1 Transmission To Human Cervix Using Reporter Virus Technologies, Dana Frances Indihar
All ETDs from UAB
Around 39 million people globally are currently infected with Human immunodeficiency virus 1 (HIV-1), more than half of whom are women. HIV-1 is a retrovirus that infects and depletes an individual’s immune cells, culminating in the development of acquired immunodeficiency syndrome (AIDS) if not managed with anti-retroviral therapies (ART). Most women acquire HIV-1 through heterosexual intercourse. However, the early mechanisms and virologic determinants of HIV-1 transmission to women remain unclear. Herein, we demonstrate transmitted/founder (TF) HIV-1 representing two genetically and pathogenically distinct subtypes (A and D) in vivo have distinct replication phenotypes in an ex vivo cervical explant tissue (CET) …
Partial Anomalous Pulmonary Venous Return Is A Rare Cause Of Pulmonary Arterary Hypertension, Ahmed Ali, Wesam Hritani, Farrah Ibrahim, Abdul Hritani
Partial Anomalous Pulmonary Venous Return Is A Rare Cause Of Pulmonary Arterary Hypertension, Ahmed Ali, Wesam Hritani, Farrah Ibrahim, Abdul Hritani
UAB Huntsville Research Day - All Presentations
2024 clinical vignette poster
Urinothorax: A Unique Case Of Exudative Pleural Effusion, Ahmed Ali, Jesse Faulk
Urinothorax: A Unique Case Of Exudative Pleural Effusion, Ahmed Ali, Jesse Faulk
UAB Huntsville Research Day - All Presentations
2024 clinical vignette poster
A Unique Case Of Primary Pulmonary Cryptococcosis Presenting With Bilateral Lung Nodules, Soumyadeep Bag, Farrah Ibrahim, Ali Hachem, Zohra Chaudhry
A Unique Case Of Primary Pulmonary Cryptococcosis Presenting With Bilateral Lung Nodules, Soumyadeep Bag, Farrah Ibrahim, Ali Hachem, Zohra Chaudhry
UAB Huntsville Research Day - All Presentations
2024 clinical vignette poster
Single Swollen Joint In A Child - To Worry Or Not To Worry, Nancy Blevins, Seth Hunt
Single Swollen Joint In A Child - To Worry Or Not To Worry, Nancy Blevins, Seth Hunt
UAB Huntsville Research Day - All Presentations
2024 clinical vignette poster
Sildenafil’S Remarkable Impact In Near-Drowning Survival, Audrey Driver, Pashitha Nimmagadda, Kiyoshi Scissum
Sildenafil’S Remarkable Impact In Near-Drowning Survival, Audrey Driver, Pashitha Nimmagadda, Kiyoshi Scissum
UAB Huntsville Research Day - All Presentations
2024 clinical vignette poster
Complications Of Flow Diversion In Unruptured Intracranial Aneurysms: A Systematic Review, Evan Gross, Anurag Modak, Andrew Yang, Sanjeev Sreenivasan, Gaurav Gupta
Complications Of Flow Diversion In Unruptured Intracranial Aneurysms: A Systematic Review, Evan Gross, Anurag Modak, Andrew Yang, Sanjeev Sreenivasan, Gaurav Gupta
UAB Huntsville Research Day - All Presentations
2024 clinical vignette poster
Missed History = Missed Histoplasmosis, Kyle Hodson, Lauren Kois, Shivani Malhotra
Missed History = Missed Histoplasmosis, Kyle Hodson, Lauren Kois, Shivani Malhotra
UAB Huntsville Research Day - All Presentations
2024 clinical vignette poster
The Pituitary Precipitates Precocious Puberty: A Case Report On Central Precocious Puberty, Madison Jeziorski, Audrey Shoemaker, Chandler Stisher
The Pituitary Precipitates Precocious Puberty: A Case Report On Central Precocious Puberty, Madison Jeziorski, Audrey Shoemaker, Chandler Stisher
UAB Huntsville Research Day - All Presentations
2024 clinical vignette poster
Rare Long-Term Sequela Of Covid-19: Brainstem Encephalitisemory, Emory Johnson, Lauren Usrey, Tejanand Mulpur
Rare Long-Term Sequela Of Covid-19: Brainstem Encephalitisemory, Emory Johnson, Lauren Usrey, Tejanand Mulpur
UAB Huntsville Research Day - All Presentations
2024 clinical vignette poster
Stressed In Silence: A Case Report On Selective Mutism, Emory Johnson, Abbey Zane, Janaki Nimmagadda
Stressed In Silence: A Case Report On Selective Mutism, Emory Johnson, Abbey Zane, Janaki Nimmagadda
UAB Huntsville Research Day - All Presentations
2024 clinical vignette poster
Anxiety: An Underlying Source Of Cannabis Hyperemesis, Fizza Mahmood, Clinton Martin
Anxiety: An Underlying Source Of Cannabis Hyperemesis, Fizza Mahmood, Clinton Martin
UAB Huntsville Research Day - All Presentations
2024 clinical vignette poster
A Possible Linkage Between Alpha 1 Antitrypsin (Aat) Deficiency And Diabetes, Fizza Mahmood, Steffane Battle
A Possible Linkage Between Alpha 1 Antitrypsin (Aat) Deficiency And Diabetes, Fizza Mahmood, Steffane Battle
UAB Huntsville Research Day - All Presentations
2024 clinical vignette poster
Pyoderma Gangrenosum, The Great Wound Masquerader, Paul Morris, Rohan Pareek, Farrah Ibrahim
Pyoderma Gangrenosum, The Great Wound Masquerader, Paul Morris, Rohan Pareek, Farrah Ibrahim
UAB Huntsville Research Day - All Presentations
2024 clinical vignette poster
Gradual Dose Reduction In Hashimoto's Hypothyroidism Diagnosed In Childhood - A Leap Of Faith, Raymond Moosavi, Eric Wells
Gradual Dose Reduction In Hashimoto's Hypothyroidism Diagnosed In Childhood - A Leap Of Faith, Raymond Moosavi, Eric Wells
UAB Huntsville Research Day - All Presentations
2024 clinical vignette poster
The Weight Loss Enigma: Balancing New Drugs With Mental Health Risks, Bryan Mortimer, Tarak Vasavada
The Weight Loss Enigma: Balancing New Drugs With Mental Health Risks, Bryan Mortimer, Tarak Vasavada
UAB Huntsville Research Day - All Presentations
2024 clinical vignette poster
When Inspection Is Cleft Out, Javier Nishikawa, Morgan Read Martin, Shivani Malhotra
When Inspection Is Cleft Out, Javier Nishikawa, Morgan Read Martin, Shivani Malhotra
UAB Huntsville Research Day - All Presentations
2024 clinical vignette poster
Calcification Crisis: A Urology Case Report On The Rare Adverse Effects Of Mitomycin, Savannah Petrus, Owen Cunneely, Joseph Pettus
Calcification Crisis: A Urology Case Report On The Rare Adverse Effects Of Mitomycin, Savannah Petrus, Owen Cunneely, Joseph Pettus
UAB Huntsville Research Day - All Presentations
2024 clinical vignette poster