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Thomas Jefferson University

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Articles 14191 - 14220 of 16394

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Bladder Inflammatory Transcriptome In Response To Tachykinins: Neurokinin 1 Receptor-Dependent Genes And Transcription Regulatory Elements, Ricardo Saban, Cindy Simpson, Rajanikanth Vadigepalli, Sylvie Memet, Igor Dozmorov, Marcia R. Saban May 2007

Bladder Inflammatory Transcriptome In Response To Tachykinins: Neurokinin 1 Receptor-Dependent Genes And Transcription Regulatory Elements, Ricardo Saban, Cindy Simpson, Rajanikanth Vadigepalli, Sylvie Memet, Igor Dozmorov, Marcia R. Saban

Department of Pathology, Anatomy, and Cell Biology Faculty Papers

Background Tachykinins (TK), such as substance P, and their neurokinin receptors which are ubiquitously expressed in the human urinary tract, represent an endogenous system regulating bladder inflammatory, immune responses, and visceral hypersensitivity. Increasing evidence correlates alterations in the TK system with urinary tract diseases such as neurogenic bladders, outflow obstruction, idiopathic detrusor instability, and interstitial cystitis. However, despite promising effects in animal models, there seems to be no published clinical study showing that NK-receptor antagonists are an effective treatment of pain in general or urinary tract disorders, such as detrusor overactivity. In order to search for therapeutic targets that could …


Welcome To Our Newest Senior Scholars May 2007

Welcome To Our Newest Senior Scholars

Population Health Matters (Formerly Health Policy Newsletter)

No abstract provided.


Subscribe To American Journal Of Medical Quality May 2007

Subscribe To American Journal Of Medical Quality

Population Health Matters (Formerly Health Policy Newsletter)

No abstract provided.


Department Of Health Policy Presentations And Publications May 2007

Department Of Health Policy Presentations And Publications

Population Health Matters (Formerly Health Policy Newsletter)

No abstract provided.


Delaware Valley Schweitzer Fellowship Program Update, Nicole M. Cobb May 2007

Delaware Valley Schweitzer Fellowship Program Update, Nicole M. Cobb

Population Health Matters (Formerly Health Policy Newsletter)

No abstract provided.


The Growing Need For Managed Care -- And Flexible Care Models -- In Medicaid And Long-Term Care Programs, Arthur Pelberg May 2007

The Growing Need For Managed Care -- And Flexible Care Models -- In Medicaid And Long-Term Care Programs, Arthur Pelberg

Population Health Matters (Formerly Health Policy Newsletter)

No abstract provided.


Shape-It: The Stroke , Hypertension, And Prostate Education Intervention Team, Michael P. Rosenthal May 2007

Shape-It: The Stroke , Hypertension, And Prostate Education Intervention Team, Michael P. Rosenthal

Population Health Matters (Formerly Health Policy Newsletter)

No abstract provided.


Medication Safety: Who's Accountable?, Hedy Cohen May 2007

Medication Safety: Who's Accountable?, Hedy Cohen

Population Health Matters (Formerly Health Policy Newsletter)

No abstract provided.


Practice-Based, Guided Self-Assessment For Improved Patients Care: Performance Improvement Cme, Jeanne G. Cole May 2007

Practice-Based, Guided Self-Assessment For Improved Patients Care: Performance Improvement Cme, Jeanne G. Cole

Population Health Matters (Formerly Health Policy Newsletter)

No abstract provided.


Allhat: An Example For Observing Early Guideline Adoption Patterns May 2007

Allhat: An Example For Observing Early Guideline Adoption Patterns

Population Health Matters (Formerly Health Policy Newsletter)

No abstract provided.


Sunshine Is The Best Disinfectant, Bettina Berman, David B. Nash May 2007

Sunshine Is The Best Disinfectant, Bettina Berman, David B. Nash

Population Health Matters (Formerly Health Policy Newsletter)

No abstract provided.


Microrna Genes Are Frequently Located Near Mouse Cancer Susceptibility Loci., Cinzia Sevignani, George A. Calin, Stephanie C. Nnadi, Masayoshi Shimizu, Ramana V. Davuluri, Terry Hyslop, Peter Demant, Carlo M. Croce, Linda D. Siracusa May 2007

Microrna Genes Are Frequently Located Near Mouse Cancer Susceptibility Loci., Cinzia Sevignani, George A. Calin, Stephanie C. Nnadi, Masayoshi Shimizu, Ramana V. Davuluri, Terry Hyslop, Peter Demant, Carlo M. Croce, Linda D. Siracusa

Department of Microbiology and Immunology Faculty Papers

MicroRNAs (miRNAs) are short 19- to 24-nt RNA molecules that have been shown to regulate the expression of other genes in a variety of eukaryotic systems. Abnormal expression of miRNAs has been observed in several human cancers, and furthermore, germ-line and somatic mutations in human miRNAs were recently identified in patients with chronic lymphocytic leukemia. Thus, human miRNAs can act as tumor suppressor genes or oncogenes, where mutations, deletions, or amplifications can underlie the development of certain types of leukemia. In addition, previous studies have shown that miRNA expression profiles can distinguish among human solid tumors from different organs. Because …


Download The Pdf Of The Entire Issue May 2007

Download The Pdf Of The Entire Issue

Jefferson Surgical Solutions

No abstract provided.


Jss Editorial Board & Credits May 2007

Jss Editorial Board & Credits

Jefferson Surgical Solutions

No abstract provided.


News In Brief May 2007

News In Brief

Jefferson Surgical Solutions

No abstract provided.


Three Recent Gifts To The Department Of Surgery May 2007

Three Recent Gifts To The Department Of Surgery

Jefferson Surgical Solutions

No abstract provided.


On The Job May 2007

On The Job

Jefferson Surgical Solutions

No abstract provided.


Innovative Therapies For Pancreatic-Related Cancers May 2007

Innovative Therapies For Pancreatic-Related Cancers

Jefferson Surgical Solutions

No abstract provided.


Resident Update: Where Are They Now? May 2007

Resident Update: Where Are They Now?

Jefferson Surgical Solutions

No abstract provided.


Acute Care Surgery Division Continues To Expand May 2007

Acute Care Surgery Division Continues To Expand

Jefferson Surgical Solutions

No abstract provided.


Overview: Nsqip Update May 2007

Overview: Nsqip Update

Jefferson Surgical Solutions

No abstract provided.


Pancreatic Cancer: When The Stakes Are High . . . May 2007

Pancreatic Cancer: When The Stakes Are High . . .

Jefferson Surgical Solutions

No abstract provided.


Download The Pdf Of The Full Issue May 2007

Download The Pdf Of The Full Issue

Jefferson Surgical Solutions

No abstract provided.


Jss Editorial Board & Credits May 2007

Jss Editorial Board & Credits

Jefferson Surgical Solutions

No abstract provided.


News In Brief May 2007

News In Brief

Jefferson Surgical Solutions

No abstract provided.


A Legacy Of Leadership: Dr. Francis E. Rosato, Sr. May 2007

A Legacy Of Leadership: Dr. Francis E. Rosato, Sr.

Jefferson Surgical Solutions

No abstract provided.


On The Job May 2007

On The Job

Jefferson Surgical Solutions

No abstract provided.


Visualizing New Possibilities In Vascular Surgery May 2007

Visualizing New Possibilities In Vascular Surgery

Jefferson Surgical Solutions

No abstract provided.


Meet Our Surgical Interns May 2007

Meet Our Surgical Interns

Jefferson Surgical Solutions

No abstract provided.


Trends In Plastic And Reconstructive Surgery May 2007

Trends In Plastic And Reconstructive Surgery

Jefferson Surgical Solutions

No abstract provided.