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Delivery Of Bikdd Proapoptotic Gene In Peptide-18 Targeted Poly(2-Oxazoline)-Dope Nanoliposomes For Breast Cancer Models, Zeynep Büşra Bolat, Ayça Ece Nezi̇r, Ongun Mehmet Saka, Itir Ebru Zemheri̇, Sevgi̇ Gülyüz, Umut Uğur Özköse, Özgür Yilmaz, Asuman Bozkir, Di̇lek Telci̇, Fi̇kretti̇n Şahi̇n

Turkish Journal of Biology

Breast cancer is the most common cancer type and the major cause of death in females worldwide. For effective breast cancer treatment, systems with promising delivery of anticancer agents is an important strategy. Peptide 18 (P18), a tumor homing peptide, shows high binding affinity towards breast cancer cells. Nanoliposomes are known to have enhanced accumulation ability in tumors with longer systemic circulation. Poly (2-ethyl-2-oxazoline) (PEtOx) polymers conjugated with DOPE were used to prepare PEtOx-DOPE nanoliposomes. BikDD is a mutant form of Bik gene, a member of the BH3-only proapoptotic genes, mimics the constitutively phosphorylated form of the gene. To the …

Pterostilbene Suppresses Head And Neck Cancer Cell Proliferation Via Induction Of Apoptosis, Tali̇h Özdaş, Si̇bel Özdaş, İpek Canatar, Erdem Kaypak

Turkish Journal of Biology

Background/aim: Head and neck cancer (HNC) is one of the most prevalent causes of death worldwide, and the discovery of anticancer agents for its prevention is very important. Pterostilbene (PS) is a trans-stilbene reported to be beneficial in managing various cancers. The objective of the study was to evaluate the cytotoxic, anti-proliferative, pro-apoptotic and anti-migrative effect of PS on HEp-2, SCC-90, SCC-9, FaDu and Detroit-551 cell lines. Materials and Methods: MTT and live/dead assays were employed to assess cell-viability, while cell migration test was performed to evaluate wound healing capacity. The mRNA, protein and intracellular expression level of CASP-3, BAX …

Optical Imaging And Gene Transfection Potential Of Linear Polyethylenimine Coated Ag2s Near-Infrared Quantum Dots, Altay Savalan

Turkish Journal of Biology

Background/aimApplication of biocompatible heavy metal free and cationic Ag2S NIR QDs, which are highly luminesce in the medical range (700-900 nm), as a non-viral gene delivery system paves the way to overcome the auto-fluorescence and easily track the delivery of the genes in real time as it happens.Materials and methodsHere, the newly developed small and colloidally stable 2-mercaptopropionic acid (MPA)-capped Ag2S aqueous quantum dots electrostatically complexed with linear polyethyleneimine (LPEI) (Ag2S@2MPA/LPEI) was investigated for the first time both as a strong fluorescent probe and as a non-viral gene delivery vector for the highest tracking of the system and delivery of …

Assessing The Impact Of Land Use Change On Carbon And Soil Quality In Kashmir Himalayas, Yasir Hanif Mir, Mumtaz A. Ganie, Zahoor A. Baba, Shakeel Mir, M. Auyoub Bhat, Javid Ahmad Bhat, Aabid H. Lone, Fehim Jeelani Wani, Shuraik Kader, Lizny Jaufer, Artan Hysa, Alban Kuriqi

Turkish Journal of Agriculture and Forestry

The Kashmir Himalayas, a region of immense ecological importance, have experienced profound degradation by land-use changes, raising concerns about sustainability. This degradation carries significant global implications, including carbon loss, soil quality deterioration, habitat destruction, and loss of biodiversity. This study investigates various key land uses, including economically vital cash crops such as apples and saffron, the socially significant staple food crop rice, forest, and pasture systems. Findings reveals that forest and pasture maintain significantly better physical, chemical, microbial, and enzymes activities, and exhibit greater soil nutrient reserves and soil organic carbon (SOC) pools. Specifically, forest soils contain 20.21%, 28.22%, and …

Changes In The Bioactivity Of Einkorn Wheat During The Maturation Period And Theireffect On The Properties Of Einkorn Bread, Mehmet Fati̇h Erkölenci̇k, Burcu Kahraman, Görkem Özülkü, Eray Tulukçu, Hamza Göktaş, Osman Sağdiç, Muhammet Arici

Turkish Journal of Agriculture and Forestry

Immature cereals may contain higher levels of nutrients than mature cereals. Immature and mature einkorn wheats werecompared in terms of physicochemical, technological, rheological, and nutritional qualities and their performances for making breadwere revealed. The values for thousand grain weight, hectoliter weight, sedimentation value and falling number of immature andmature einkorn wheat samples were 23.25–32.29 (g), 72.32–79.11 (kg/hL), 15.02–18.07 (mL) and 312–341 (sec), respectively (p ≤ 0.05).Immature einkorn wholegrain flour (IEWF) contains more than twofold mineral substance than mature einkorn wholegrain flour(MEWF). The total phenolic content and antioxidant properties of IEWF were found to be higher than those of MEWF. The …

Plastome Analysis Of Cultivated Apricots: Genome Structure, Nucleotide Diversity, And Phylogeny, Lungelo Khanyile, Kahraman Gürcan

Turkish Journal of Agriculture and Forestry

The genetic diversity and evolution of plastomes in P. armeniaca L. (common/cultivated apricot) have been poorly studied.Complete plastomes of 20 accessions and 10 F1 hybrids, identified as P. armeniaca L., were de novo assembled filtering from total DNAnt reads. These plastomes were subsequently analyzed with the Prunus genus accessions retrieved from the GenBank. The plastomesexhibited conservation of genomic structure, gene organization and order, with lengths ranging from 158,057 nt to 158,089 nt,displaying a narrow size variation. Except for “Zard” and its hybrids, the plastomes of apricot genotypes from different regions showedonly three haplotypes, indicating narrow genetic diversity in cultivated P. …

Global Metabolome Profiles Of Lonicera Caerulea L. And Lonicera Caerulea Ssp.Kamtschatica (Sevast.) Gladkova, Muhammad Amjad Nawaz, Mayya P. Razgonova, Elena A. Rusakova, Elena N. Petrusha, Andrey S. Sabitov, Olga A. Chunikhina, Sezai̇ Erci̇şli̇, Nadezhda G. Tikhonova, Kirill S. Golokhvast

Turkish Journal of Agriculture and Forestry

Lonicera caerulea, commonly known as honeysuckle, is widespread in the Eurasian continent. Its berries are rich in bioactive compounds. However, limited studies have explored the metabolome composition of the berries of varieties and wild accessions in different subspecies of L. caerulea. Here we studied the metabolomic compositions of four varieties of L. caerulea ssp. caerulea and one variety and five wild accessions of L. caerulea ssp. kamtschatica (Sevast.) Gladkova, by using HPLC-ESI-MS and ESI-MS/MS analyses. We report the identification of 151 compounds in the two L. caerulea subspecies. In total, 88 and 84 compounds were detected in L. caerulea and …

Cover And Contents

Turkish Journal of Agriculture and Forestry

No abstract provided.

Alternative Scenarios For The Lhc Based Electron-Proton Collider, Ahmet Nuri̇ Akay, Burak Dağli, Bora Ketenoğlu, Ari̇f Öztürk, Saleh Sultansoy

Turkish Journal of Physics

Construction of the ERLC (twin LC) collider tangential to LHC will allow investigating ep collisions at essentially higher center-of-mass energies than ERL-50 and LHC based ep collider. Luminosity estimations show that values well exceeding 1034 cm−2s−1 can be achieved for ERLC and HL-LHC based ep colliders. Certainly, proposed ep colliders have great potential for clarifying QCD basics and new physics search in addition to providing precise PDFs for adequate interpretation of the LHC experimental data. Another alternative to the ERL-50 is to construct an e-ring with the same energy and length. In this case, luminosity of order 1034cm−2s−1 can be …

Monitoring Cow Behavior Based On Lying, Standing, Eating, And Ruminating Recognition Using Yolov8, Ali Saifudin, Sri Pantja Madyawati, Imam Yuadi, Rimayanti Rimayanti, Imam Mustofa, Riries Rulaningtyas, Teddy Surya Gunawan, Adnan Rahmat Anom Besari

Turkish Journal of Veterinary & Animal Sciences

Cow behavior is a crucial indicator for monitoring health, reproductive status, and welfare in livestock management. However, methods that rely on wearable devices often face significant challenges, including high costs, maintenance difficulties, and potential impacts on animal welfare. To address these limitations, this study explored the potential of using YOLOv8, a cutting-edge computer vision model, for non-invasive monitoring of cow behavior. The research methodology involved four key steps: data collection, preliminary data processing, model training, and validation. The findings revealed that YOLOv8 is capable of accurately detecting and localizing key cow behaviors—lying, standing, eating, and ruminating—achieving a mean average precision …

Diversity Of Cnidaria And Ctenophora From The Coasts Of Türkiye, Meli̇h Ertan Çinar, Şermi̇n Açik, Hali̇m Vedat Aker

Turkish Journal of Zoology

The compilation of papers on the phyla Cnidaria and Ctenophora inhabiting the coasts of Türkiye (Black Sea, Sea of Marmara,Aegean Sea, and Levantine Sea) together with the new records of cnidarian species presented in this study yielded 296 cnidarian and8 ctenophore species. Among the cnidarian groups, Hydrozoa were represented by 160 species, Scyphozoa by 16 species, Anthozoa by87 species, and Myxozoa by 31 species. The number of species of cnidarians and ctenophores varies greatly between regions due to thedifferent environmental conditions of the seas and the level of scientific effort in each sea. A total of 47 cnidarian and five …

Diversity Of Fishes Along The Coast Of Türkiye, Murat Bi̇lecenoğlu

Turkish Journal of Zoology

The Turkish marine fish diversity was revised and updated in this study based on data published in the last decade. There arecurrently 552 species in the inventory, reflecting an increase of 7.8% since the previous checklist and belonging to the classes of Teleostei(479 spp.), Elasmobranchii (68 spp.), Chondrostei (3 spp.), Petromyzonti (1 sp.), and Holocephali (1 sp.). Twelve species were excludedfrom the faunal list due to the lack of valid proof of their presence, the distribution ranges of an additional 12 species were corrected, twonew records (Istiompax indica (Cuvier, 1832) and Mola alexandrini (Ranzani, 1839)) previously unknown from Türkiye were …

Diversity Of Marine Tetrapods (Reptiles, Seabirds, And Mammals) Along The Coasts Of Türkiye, Harun Güçlüsoy, Ortaç Onmuş

Turkish Journal of Zoology

This paper presents the occurrence of a total of 72 marine tetrapod species, comprising 3 sea turtles, 54 seabirds, and 15 marine mammals. The distribution of each reported species along the Black Sea, Sea of Marmara, Aegean, and Levantine coasts of Türkiye is described with key references.

Diversity Of Bryozoa Along The Coasts Of Türkiye, Ferah Koçak, Si̇nem Aydin

Turkish Journal of Zoology

The current status of bryozoan species distributed along the coast of Türkiye were revised and an updated checklist including 185 species (24 cyclostomatids, 20 ctenostomatids and 141 cheilostomatids) was presented. Cheilostomes largely prevail (141 species, 87 genera and 50 families) followed by cyclostomes (24 species, 15 genera and 9 families) and ctenostomes (20 species, 9 genera and 8 families) in bryozoan fauna of Türkiye. The distribution of species and genera highlights the Aegean Sea as the most diverse, hosting 146 species. In this study, Hornera frondiculata (Lamarck, 1816), Amathia verticillata (delle Chiaje, 1822), Bugulina fulva (Ryland, 1960), Tricellaria inopinata d'Hondt …

Corrigendum To “A Two-Stage Deformation Of The Anatolian Plate Deduced Frompaleomagnetic Signals: The Initial Age Of The Anatolian’S Escape” [Turkish Journal Ofearth Sciences 33 (3) 2024 243-259 ], Mualla Cengi̇z, Savaş Karabulut

Turkish Journal of Earth Sciences

This corrigendum is to address an issue regarding the manuscript's previous title. The authors have regrettably noticed that the title is incorrect in the original published version of this paper. To rectify this oversight and ensure the accuracy of the published work, the title has been corrected for your reference below: A two-stage deformation of the Anatolian plate deduced from paleomagnetic signals: the initial age of the Anatolian escape.

Link to the original submission: https://journals.tubitak.gov.tr/earth/vol33/iss3/2/

Assessment Of Water Pollution In A Waste Storage Drainage Area (A Case Study In Eskişehir, Türkiye), Ali̇ Kayabaşi, Özlem Toygar Sağin, Candan Gökçeoğlu

Turkish Journal of Earth Sciences

Before 2016, the Eskişehir city landfill was an irregular landfill. Since then, it has been transformed into a regulated landfill. This study aimed to investigate the presence of pollution in the landfill drainage area. For this purpose, water samples were collected from the landfill drainage area and the Kadirbey Farm Spring, upstream of the landfill area, during the rainy and dry seasons of 2021. Analyses of the heavy metal content, total dissolved soil (TDS), chemical oxygen demand, biochemical oxygen demand, pH, phenol material content, ammonia nitrogen content, and conductivity were conducted on the samples. Electrical resistivity tomography (ERT) measurements were …

Detecting Edges Of Geologic Sources From Gravity Or Magnetic Anomalies Through A Novel Algorithm Based On Hyperbolic Tangent Function, Hanbing Ai, Yunus Levent Eki̇nci̇, Ahmad Alvandi, Hazel Deni̇z Toktay, Çağlayan Balkaya, Arka Roy

Turkish Journal of Earth Sciences

Directional derivative-based edge detectors are commonly used to outline the abrupt lateral variations in densities or magnetizations of geologic sources from potential-field datasets. Some subtle traces of faults, lithological contacts, and lineaments can be made more visible on anomaly maps using these algorithms. However, these algorithms generally suffer from common limitations such as blurry edges with low-resolution or faulty boundaries. To minimize these challenges, we proposed a new efficient edge detector that benefits from the hyperbolic tangent function. The performance of this detector was tested on the responses of a synthetic gravity model and Bishop's complex magnetic model. A Gaussian …

An Archaeological And Archaeoseismological Perspective On Earthquakes In The Coastal Cities Of Western Anatolia In The 3rd Millennium Bce: Settlement Abandonment And Changes In Social Structures, Ümi̇t Gündoğan

Turkish Journal of Earth Sciences

This study investigates the impact of the earthquakes that occurred in the first half of the 3rd millennium BCE on Western Anatolian settlements, aiming to determine the dates of the earthquakes that happened during the prehistoric period using the earthquake layers of the settlements and associated C14 data. The focus of the paper is the investigation of the effects of two earthquakes that occurred in the region during the first half of the 3rd millennium BCE on the settlements of the region. The first earthquake occurred around 2800 BCE and damaged settlements in the area of İzmir. Evidence of this …

Gamma-Aminobutyric Acid Induction Of Triticale Protective Systems Under Drought, Salt Stress Or A Combination Of The Two, Yuriy Kolupaev, Ivan V. Shakhov, Alexander I. Kokorev, Liana I. Relina, Alla I. Dyachenko, Alexander P. Dmitriev

Turkish Journal of Botany

Gamma-aminobutyric acid (GABA) is currently considered to be an important stress metabolite with regulatory functions in plants. Exogenous GABA is known to be able to enhance the tolerance of different plant species to drought and salt stress. However, its effects on the functioning of stress-protective systems in triticale, an intergeneric wheat-rye hybrid with specific adaptation strategies to abiotic stresses, remained completely unstudied. We studied the effects of exogenous GABA (0.5 mM) on the growth as well as on the antioxidant and osmoprotective systems of triticale seedlings (cv. 'Rarytet') under simulated drought (15% PEG 6000), salt stress (100 mM NaCl), or …

Pollination Is A Major Driver Of Germination In Comanthera Bisulcata And May Improve Everlasting Flowers (Sempre-Vivas) Conservation In Brazilian Campos Rupestres, Maria Luiza De Azevedo, Maria Neudes De Sousa Oliveira, André Rodrigo Rech, Gudryan Jackson Baronio, Jose Carlos Barbosa Dos Santos, Evandro Luiz Mendonca Machado, Israel Marinho Pereira, Eric Bastos Gorgens

Turkish Journal of Botany

The campos rupestres, ecosystems that are both unique and highly diverse, are home to a variety of endemic species, including Comanthera bisulcata (Eriocaulaceae). This species, of economic importance, has its inflorescences used in handicrafts due to the fact that they retain the appearance of living structures even after being harvested and dried. The trade of these inflorescences depends almost exclusively on extraction, an activity of great importance for the traditional communities of the Espinhaço Meridional municipalities, in Minas Gerais. However, research is essential to improve the management of this native species. In this study, we highlight the importance of pollination …

A New Species Of Nigrospora (Apiosporaceae) In Corylus Heterophylla In China, Jing Wang, Zhong-Xuan Liu, Wei Yu, Chao Kang, Yi Hua Yang

Turkish Journal of Botany

Corylus heterophylla, the majestic hazelnut tree, stands as one of the esteemed quartet of grand nuts reigning across the landscapes of temperate Asia, Europe, and North America. But its relationship with endophytic fungi remains thinly explored. This study successfully identified a new species designated as Nigrospora coryli through conjoint analysis of morphology and systematics. The genetic regions examined encompassed ITS, TUB2, and TEF1-α.The detailed morphological description, colour photographs of Macro- and microcharacters are presented.

Cover And Contents

Turkish Journal of Electrical Engineering and Computer Sciences

No abstract provided.

Power Quality Enhancement In Hybrid Pv-Bes System Based On Ann-Mppt, Heli̇n Bozkurt, Özgür Çeli̇k, Ahmet Teke

Turkish Journal of Electrical Engineering and Computer Sciences

Battery energy systems (BESs) assisted photovoltaic (PV) plants are among the popular hybrid power systems in terms of energy efficiency, energy management, uninterrupted power supply, grid-connected and off-grid availability. The primary objective of this study is to enhance the power quality of a grid-tied PV-BES hybrid system by developing an operation strategy based on Artificial Neural Network (ANN) based maximum power point tracking (MPPT) method. A test system comprising a 10-kWh BES and a 12.4 kW PV plant is structured and simulated on the MATLAB/Simulink platform. The hybrid system is validated with three different cases: constant radiation, rapid changing radiation, …

Mention Detection In Turkish Coreference Resolution, Şeni̇z Demi̇r, Hani̇fi̇ İbrahi̇m Akdağ

Turkish Journal of Electrical Engineering and Computer Sciences

A crucial step in understanding natural language is detecting mentions that refer to real-world entities in a text and correctly identifying their boundaries. Mention detection is commonly considered a preprocessing step in coreference resolution which is shown to be helpful in several language processing applications such as machine translation and text summarization. Despite recent efforts on Turkish coreference resolution, no standalone neural solution to mention detection has been proposed yet. In this article, we present two models designed for detecting Turkish mentions by using feed-forward neural networks. Both models extract all spans up to a fixed length from input text …

A Single Operational Amplifier-Based Grounded Meminductor Mutators And Their Applications, Shalini Gupta, Kunwar Singh, Shireesh Kumar Rai

Turkish Journal of Electrical Engineering and Computer Sciences

In this work, three simple configurations of meminductor mutator are presented. The first two configurations of meminductor mutator have been implemented utilizing one CMOS-based operational amplifier, one memristor, one capacitor, and five resistors, while the third configuration of meminductor mutator is implemented utilizing one CMOS based operational amplifier, two memristors, one capacitor, and four resistors. The implementation and simulation of the proposed configurations are done by using LTspice tool. The viability of the proposed circuits is demonstrated by utilizing TSMC 180 nm CMOS technology parameters. The proposed circuits of the meminductor have a simple structure in contrast to many of …

Finger Movement Recognition Using Machine Learning Algorithms With Tree-Seed Algorithm, Muhammed Sami̇ Karakul, Ahmet Gökçen

Turkish Journal of Electrical Engineering and Computer Sciences

Electromyography (EMG) signals have been used to recognize various actions of hand movements, finger movements, and hand gestures. This paper aims to improve the classification accuracy of EMG signals while decreasing the number of features using the Tree-Seed Algorithm. The dataset containing EMG signals utilized in this investigation is derived from a publicly accessible source. The rationale for selecting the Tree-Seed Algorithm centers on its ability to enhance classification accuracy while minimizing the dimensionality of feature sets. The object function and Tree-Seed Algorithm's nature avoids the results to have low accuracy with fewer features. The aim is not just to …

Enhancing Dtc Control Of Im Using Fuzzy Logic And Three-Level Inverter: A Comparative Study, Siham Mencou, Majid Benyakhlef, Elbachir Tazi

Turkish Journal of Electrical Engineering and Computer Sciences

Direct torque control is the most appropriate strategy for induction motor drive systems, due to its considerable ability to reduce the impact of of machine parameter variations, while offering fast dynamic response and simplified control implementation. However, persistent problems associated with high torque ripple and variable switching frequencies prevent its widespread adoption. To overcome these limitations, several techniques have been developed, in particular the use of multi-level inverters and fuzzy logic algorithms. This article proposes an in-depth evaluation of these techniques in a MATALB/Simulink environment, under various operational conditions. The main objective is to provide a detailed performance analysis of …

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Turkish Journal of Mathematics

No abstract provided.

Comprehensive Computational Study On Transient Heat Transfer In Functionally Graded Longitudinal Fins Under Time-Varying Laser Heating, Hüseyi̇n Demi̇r, İnci̇ Çi̇li̇ngi̇r Süngü, İbrahi̇m Keleş

Turkish Journal of Mathematics

The present study assumes that the material properties of the fin vary by a force rule in the axial direction, with the exception of the thermal relaxation coefficient, which is assumed to be constant. The temperature distribution in the longitudinal fin with homogeneous cross-section exposed to the laser heat source is numerically investigated. This is because these constraints lead to a linear differential equation with partial solutions that can't be analytically resolved using conventional methods, except for a few elementary order functions. Consequently, a linear or non-linear system of equations as a function of time is obtained by transforming a …

A Note On The Hull And Linear Complementary Pair Of Cyclic Codes, Zohreh Aliabadi, Tekgül Kalayci

Turkish Journal of Mathematics

The Euclidean hull of a linear code C is defined as C ∩ C⊥ , where C⊥ denotes the dual of C underthe Euclidean inner product. A linear code with the trivial hull is called a linear complementary dual (LCD) code. Apair (C,D) of linear codes of length n over the finite field Fq is called a linear complementary pair (LCP) of codes ifC ⊕ D = Fnq. More generally, a pair (C,D) of linear codes of the same length over Fq is called a linear ℓ -intersectionpair of codes if C ∩D has dimension ℓ as a vector space …