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A Surface-Based Approach For 3d Approximate Convex Decomposition, Onat Zeybek Kuşkonmaz, Yusuf Sahi̇lli̇oğlu
A Surface-Based Approach For 3d Approximate Convex Decomposition, Onat Zeybek Kuşkonmaz, Yusuf Sahi̇lli̇oğlu
Turkish Journal of Electrical Engineering and Computer Sciences
Approximate convex decomposition enables the simplification of complex shapes into manageable convex components. In this work, we propose a novel surface-based method to achieve this which leads to efficient computation times and sufficiently convex results while avoiding over-approximating the input model. We start approximation using mesh simplification. Then we iterate over the surface polygons of the mesh and divide them into convex groups. We utilize planar and angular equations to determine suitable neighboring polygons for inclusion in forming convex groups. To ensure our method outputs a sufficient result for a wide range of input shapes, we run multiple iterations of …
Lgformer: Informer-Based Personalized Modeling For Blood Glucose Prediction, Xue Yuewei, Shaopeng Guan, Jia Wanhai
Lgformer: Informer-Based Personalized Modeling For Blood Glucose Prediction, Xue Yuewei, Shaopeng Guan, Jia Wanhai
Turkish Journal of Electrical Engineering and Computer Sciences
Effective diabetes management relies on precise prediction of blood glucose levels to minimize complications. However, the patterns and fluctuations in blood glucose vary significantly among patients, posing a challenge for existing prediction methods. Many current approaches fail to accommodate these individual differences, leading to less reliable predictions. In response to this challenge, we present LGformer, a novel prediction model based on the Informer architecture, designed to enhance both flexibility and accuracy. LGformer improves upon Informer by integrating LSTM and GRU layers into its probSparse Self-attention mechanism, allowing for personalized processing of blood glucose data tailored to each patient's unique profile. …
In-Situ Superconductor Temperature Sensor For Cryogenic Integrated Circuits, Emre Küçükyilmaz, Nazi̇f Orhun Tekci̇, Sasan Razmkhah, Ali̇ Bozbey
In-Situ Superconductor Temperature Sensor For Cryogenic Integrated Circuits, Emre Küçükyilmaz, Nazi̇f Orhun Tekci̇, Sasan Razmkhah, Ali̇ Bozbey
Turkish Journal of Electrical Engineering and Computer Sciences
Cryogenic circuits, such as those based on single flux quantum (SFQ) logic, function at extremely low temperatures. Therefore, the designs target the utilization of liquid helium (LHe) temperatures, maintaining them at 4.2 K. These specialized circuits can be subjected to measurement either within liquid helium (LHe) baths or enclosed within closed-cycle cryocoolers.However, when utilizing LHe in cryocooler systems, inherent weak thermal contact can lead to temperature gradients between the circuit chip and the cold head, where conventional temperature sensors are typically placed. To address this challenge, this study introduces an innovative on-chip temperature sensing approach that capitalizes on the temperature …
Fault Diagnosis Of Photovoltaic Array Based On Gated Residual Network With Multi-Head Self Attention Mechanism, Ahmed Mesai Belgacem, Mounir Hadef, Abdesslem Djerdir
Fault Diagnosis Of Photovoltaic Array Based On Gated Residual Network With Multi-Head Self Attention Mechanism, Ahmed Mesai Belgacem, Mounir Hadef, Abdesslem Djerdir
Turkish Journal of Electrical Engineering and Computer Sciences
Effective fault identification and diagnosis in photovoltaic (PV) arrays is vital for improving the effectiveness, and safety of solar energy systems. While various artificial intelligence methods have successfully established fault detection and diagnosis models, introducing inefficiencies and potentially overlooking useful features. Moreover, these methods often employ neural networks with limited performance capabilities. In response to these challenges, this paper introduces an innovative intelligent model that integrates a combination of a gated residual neural network (GRN) and a multi-head self-attention mechanism (MHSA). To evaluate the proposed fault diagnosis model, the small-scale PV grid system is implemented, and fault simulation experiments, including …
Computing Exterior Isoclinism Of Crossed Modules, Zekeri̇ya Arvasi̇, Alper Odabaş
Computing Exterior Isoclinism Of Crossed Modules, Zekeri̇ya Arvasi̇, Alper Odabaş
Turkish Journal of Mathematics
In this paper, we introduce exterior isoclinism for crossed modules, extending the concept of isoclinism from groups to these 2-dimensional algebraic structures. Motivated by work on tensor and exterior products of non-abelian groups, we utilize non-abelian exterior products, exterior squares, and exterior centers to define this new equivalence relation. Additionally, we provide computational tools implemented in the GAP system to identify exterior isoclinism families of small groups and crossed modules.
Moment-Based Approximation For Variance Of Semi-Markovian Random Walk With Gamma Distributed Interference Of Chance, Büşra Alakoç, Asli Bektaş Kamişlik, Tülay Yazir, Tahi̇r Khaniyev
Moment-Based Approximation For Variance Of Semi-Markovian Random Walk With Gamma Distributed Interference Of Chance, Büşra Alakoç, Asli Bektaş Kamişlik, Tülay Yazir, Tahi̇r Khaniyev
Turkish Journal of Mathematics
This study proposed moment-based approximations for the expected value and variance of the ergodic distribution of the semi-Markovian random walk process (X(t)) with gamma distributed interference of chance. Many studies have investigated analogous moment problems by using asymptotic approach. The key distinguishing aspect of this study from others in the literature is obtaining Kambo’s approximations for the moments of X(t) instead of asymptotic expansions. Firstly, the approximation formulas for the moments of boundary functional SN(z) of X(t) were obtained. Then using these results, approximation formulas for the first two moments of the ergodic distributions of X(t) were derived. Finally, the …
The 2-Adic Valuation Of Shifted Padovan And Perrin Numbers And Applications, Eric Bravo, Nuretti̇n Irmak
The 2-Adic Valuation Of Shifted Padovan And Perrin Numbers And Applications, Eric Bravo, Nuretti̇n Irmak
Turkish Journal of Mathematics
We characterize the 2-adic valuation of (Pn − 1)n≥0 , where (Pn)n≥0 denotes the Padovan sequence. In addition, we use this formula to find all the Cullen and Proth numbers that are Padovan numbers. We also fully describe the 2-adic order of (Rn + 1)n≥0 , where (Rn)n≥0 denotes the Perrin sequence, and use it to find all Woodall and Proth numbers of the second kind which are Perrin numbers. As a consequence we find that 3, 5, 9, and 65 are the only Fermat numbers in the Padovan sequence; while 3 and 7 and 2 and 5 are the …
Coefficient Problems For A Certain Subclass Of Analytic And Univalent Functions, Osman Altintaş, Ni̇zami̇ Mustafa
Coefficient Problems For A Certain Subclass Of Analytic And Univalent Functions, Osman Altintaş, Ni̇zami̇ Mustafa
Turkish Journal of Mathematics
In the present work, some new subclasses of analytic and univalent functions are introduced and some 5 geometric properties such as coefficient estimates problem are studied for them. Furthermore, we show that our results 6 are generalization for some earlier works in the literature and we show this by comparing ours with those related.
The Compositions Derived From By Changing Variable In Singular Distributions, Emi̇n Özçağ
The Compositions Derived From By Changing Variable In Singular Distributions, Emi̇n Özçağ
Turkish Journal of Mathematics
In this paper we concern further results of \cite{kn:oz9,kn:oz8} by using the method mainly related to the finite part of divergent integral, in fact we consider the powers for positive integers of the composition of the Dirac delta function and an infinitely differentiable function having any number of distinct multiple roots which will be defined as the neutrix limit of the regular sequence $\delta^k_n(f(x))$. Moreover we show that the powers of the composition $\delta(f(x))$ for negative integers can be also defined via neutrix settings. Some compositions as examples to better understand will be given.
Stratigraphy And Geochronology Of The Eocene Volcanosedimentary Units In The Hekimhan-Darende (Malatya) Region: Implications For The Development Of The Gürün Curl, Emrah Yalçin Ersoy, Osman Candan, İbrahi̇m Uysal
Stratigraphy And Geochronology Of The Eocene Volcanosedimentary Units In The Hekimhan-Darende (Malatya) Region: Implications For The Development Of The Gürün Curl, Emrah Yalçin Ersoy, Osman Candan, İbrahi̇m Uysal
Turkish Journal of Earth Sciences
We present new radiometric (Ar-Ar) age data from the volcanic rocks occurring in the Eocene strata in the Hekimhan and Gürün-Darende (Malaya) regions. The Eocene units in these regions are represented separately by the Tohma and Darende formations, respectively. The two basaltic volcanic interlayers in the Tohma Formation, occurring in the lower and upper parts of the succession yielded Ar-Ar isochron ages of 51.75±0.76 and 42.66±0.43 Ma, respectively, indicating a deposition age of Ypresian-Lutetian interval for the unit. The andesitic volcanic rocks in the basal parts of the Darende Formation yielded an Ar-Ar isochron age of 37.35±0.72 Ma, revealing that …
Anomalous Crustal Structure Beneath The Örenli-Eğiller Depression Zone, Inferred From Magnetotelluric Studies, Western Anatolia, Türkiye, Dornadula Chandrasekharam, Khasi Raju, Prabhala Bhaskhara Venkata Subba Rao, Alper Baba
Anomalous Crustal Structure Beneath The Örenli-Eğiller Depression Zone, Inferred From Magnetotelluric Studies, Western Anatolia, Türkiye, Dornadula Chandrasekharam, Khasi Raju, Prabhala Bhaskhara Venkata Subba Rao, Alper Baba
Turkish Journal of Earth Sciences
In Türkiye, the prevalence of high radiogenic granites makes them ideal locations for initiating enhanced geothermal system (EGS) projects. One such occurrence of these granites is observed in the Kozak area of the Bergama region. To assess the energy potential of this site, a magnetotelluric (MT) survey was conducted, focusing on determining the depth distribution of the intrusive granite.The survey employed dimensionality analysis, utilizing Bahr skew and phase tensor analyses that denote a 2D subsurface nature up to 100 s and beyond that a 3D nature. In the present study, we interpreted MT data up to 100 s. The data …
Processing Of Pinger, Chirp, Boomer, And Parametric Subbottom Profiler Datasets, Aslihan Nasif
Processing Of Pinger, Chirp, Boomer, And Parametric Subbottom Profiler Datasets, Aslihan Nasif
Turkish Journal of Earth Sciences
Subbottom profiler (SBP) systems are commonly employed for geo-hazard analysis in offshore engineering studies. The joint analysis of multi-channel seismic and SBP data also provides additional information for analyzing submarine fluid-flow structures in shallow sediments. Detailed geo-hazard analyses also aim to reveal small-scale changes in the seafloor and the underlying structures. Therefore, the horizontal and vertical resolution of SBP data is a crucial parameter, and obtaining the necessary resolution requires appropriate data processing.This study analyzes the steps and parameters applied in processing pinger, Chirp, boomer, and parametric SBP data, to determine an optimal data processing flow and parameters. Compared to …
Diversity And Evenness Of Birds During Seasonal Paddy Farming Practice In Southwestern Sarawak, Ivana Berlinda Bilang, Mohamad Fizl Sidq Ramji, Siti Nurlydia Sazali, Andrew Alek Tuen, Wan Nurainie Wan Ismail
Diversity And Evenness Of Birds During Seasonal Paddy Farming Practice In Southwestern Sarawak, Ivana Berlinda Bilang, Mohamad Fizl Sidq Ramji, Siti Nurlydia Sazali, Andrew Alek Tuen, Wan Nurainie Wan Ismail
Turkish Journal of Zoology
The influence of seasonal paddy farming activities on the paddy field environment and its composition of birds could be visually observed but has yet to be systematically studied and is still relatively understudied in Malaysian Borneo. Earlier research relied solely on point counts and not using line transects or mist nets for data collection could have resulted in missing and biased findings. Thus, this study aims to evaluate and compare species diversity and evenness of birds in different paddy stages in southwestern Sarawak with previous studies conducted in the region. We reported a higher species richness than previous reports from …
An Important Species For Black Sea Biodiversity: Some Population Characteristics Ofinvasive Sea Vase (Ciona Intestinalis Linnaeus, 1767) Distributed On The Sinop Shores, Zeki̇ye Bi̇ri̇nci̇ Özdemir, Eylem Aydemi̇r Çi̇l, Süleyman Özdemi̇r, Hünkar Avni̇ Duyar
An Important Species For Black Sea Biodiversity: Some Population Characteristics Ofinvasive Sea Vase (Ciona Intestinalis Linnaeus, 1767) Distributed On The Sinop Shores, Zeki̇ye Bi̇ri̇nci̇ Özdemir, Eylem Aydemi̇r Çi̇l, Süleyman Özdemi̇r, Hünkar Avni̇ Duyar
Turkish Journal of Zoology
This study aims to provide a comprehensive summary of the fundamental biological and certain population characteristics of Ciona intestinalis found along the Black Sea coasts of Turkey. The research was conducted between September 2022 and April 15, 2023, off the Sinop coast of the Black Sea, utilizing samples collected by commercial fishing vessels in the region. A total of 103 specimens of Ciona intestinalis were examined during the study. The average total length, width, and weight of Ciona intestinalis were determined to be 3.614 ± 0.089 cm, 1.967 ± 0.054 cm, and 2.004 ± 0.067 g, respectively. The length-weight relationship …
Exploring Sustainable Synthesis Paths: A Comprehensive Review Of Environmentally Friendly Methods For Fabricating Nanomaterials Through Green Chemistry Approaches, Vishu Girotra, Pritam Kaushik, Dipti Vaya
Exploring Sustainable Synthesis Paths: A Comprehensive Review Of Environmentally Friendly Methods For Fabricating Nanomaterials Through Green Chemistry Approaches, Vishu Girotra, Pritam Kaushik, Dipti Vaya
Turkish Journal of Chemistry
This comprehensive review delves into the burgeoning field of nanotechnology, where the synthesis of nanoparticles (NPs) is strategically tailored to specific applications. Embracing the principles of Green Chemistry, this approach utilizes environmentally friendly materials, such as plant extracts and microorganisms, as capping or reducing agents and solvents in the synthesis process. Notably, plant-based synthesis demonstrates enhanced stability and faster rates compared to microorganisms. The synthesized materials exhibit unique properties ranging from antimicrobial and catalytic to antioxidant and find applications across diverse fields. Green synthesis processes, characterized by mild conditions in terms of temperature and reagents, stand in stark contrast to …
Development Of Graphene Oxide-Based Biosensing Platforms For Label-Free Bioelectronic Detection Of Pathogenic Microorganisms, Sezi̇n Yüksel, Fethi̇ye Ferda Yilmaz, Hüseyi̇n Taşli, Pinar Kara
Development Of Graphene Oxide-Based Biosensing Platforms For Label-Free Bioelectronic Detection Of Pathogenic Microorganisms, Sezi̇n Yüksel, Fethi̇ye Ferda Yilmaz, Hüseyi̇n Taşli, Pinar Kara
Turkish Journal of Chemistry
A novel electrochemical nanogenosensor devoted to clinical analysis is reported for label-free detection of pathogenic microorganisms in the present work. The designed biosensor is composed of graphene oxide-modified disposable pencil graphite electrodes as a sensing platform. Escherichia coli is used as a model case. A 5ʹ-aminohexyl-linked 22-base sequence probe representing the E. coli amplicon is immobilized onto sensor surfaces via carbodiimide chemistry. Hybridization is performed with denatured PCR amplicons of the bacteria. Detection is realized by transduction with the electrochemical impedance spectrometry technique. The selectivity of the designed genosensor is measured using Mycobacterium tuberculosis and Klebsiella pneumoniae sequences. Outstanding sensitivity …
Photocatalytic Degradation Of Methylene Blue Using Cu2+-Modified Bimetallic Titanium-Based Metal Organic Framework (Mil-125) Photocatalyst With Enhanced Visible Light Activity, Gülsüm Özçeli̇k, Ferda Ci̇van Çavuşoğlu, Şahi̇ka Sena Bayazi̇t, Şeyma Özkara Aydinoğlu
Photocatalytic Degradation Of Methylene Blue Using Cu2+-Modified Bimetallic Titanium-Based Metal Organic Framework (Mil-125) Photocatalyst With Enhanced Visible Light Activity, Gülsüm Özçeli̇k, Ferda Ci̇van Çavuşoğlu, Şahi̇ka Sena Bayazi̇t, Şeyma Özkara Aydinoğlu
Turkish Journal of Chemistry
Cu-modified TiO2 nanoparticles derived from MIL-125 was prepared by solvothermal method for photocatalytic degradation methylene blue under visible light illumination. 2 wt. % Cu2+ ions are integrated into the nodes of MIL-125 framework aiming to boost the photocatalytic performance as well as the physicochemical properties of bare sample. The results showed that incorporation of 2 wt. % Cu2+ ion into MOF framework had significant influences on the crystallographic structure, morphological and optical properties of photocatalytic samples, as well as catalytic activity for methylene blue degradation reaction. The high activity profile of Cu modified TiO2 nanoparticles derived from MIL-125 might be …
Synthesis Of Isocyanate Containing Cryogels For Fast (Bio)Molecular Immobilization, Merve Bat Özmatara, Tuğçe Ni̇hal Gevrek
Synthesis Of Isocyanate Containing Cryogels For Fast (Bio)Molecular Immobilization, Merve Bat Özmatara, Tuğçe Ni̇hal Gevrek
Turkish Journal of Chemistry
Cryogels containing isocyanate reactive groups were synthesized via photopolymerization of 2-isocyanoethyl methacrylate (ICEMA) and poly(ethylene glycol) methyl ether methacrylate (PEGMEMA) monomers. Changing ratio of monomers with respect to each other, series of cryogels with varying ratio of reactive isocyanate groups were successfully prepared. Characterization of the cryogels was carried out using fourier transform infrared spectroscopy (FTIR), thermogravimetric analysis (TGA), scanning electron microscope (SEM) and rheometry techniques. To demonstrate that molecules containing amine groups can be immobilized onto the synthesized cryogels through the reaction between isocyanate and amine groups, cryogels were conjugated with 4-(trifluoromethyl)benzylamine (TFBA) and fluorescein amine (FLA) molecules, and …
Synthesis, Characterization, And Hirshfeld Surface Analysis Of Coordination Compounds Composed Of Two Different Aminopyridines, Isothiocyanate Ligand Molecules, And Two Different Transition Metal Atoms, Zari̇fe Si̇bel Şahi̇n, Zeki̇ Kartal
Synthesis, Characterization, And Hirshfeld Surface Analysis Of Coordination Compounds Composed Of Two Different Aminopyridines, Isothiocyanate Ligand Molecules, And Two Different Transition Metal Atoms, Zari̇fe Si̇bel Şahi̇n, Zeki̇ Kartal
Turkish Journal of Chemistry
This article successfully describes the synthesis of three coordination compounds formed by the ligands 3-aminopyridine, 4-aminopyridine and isothiocyanate ion with copper atoms and 4-aminopyridine and isothiocyanate ion with cadmium atoms, and their structural characterizations. The crystal structures of the compounds were determined by single crystal XRD technique. According to that technique, the open formulae of these compounds are [Cu(3-aminopyridine)2(NCS)2] (1), [Cu(4-aminopyridine)3(NCS)2] (2) and [Cd(4-aminopyridine)2(NCS)Cl] (3). In addition, the suitability of the structures of the compounds was characterized by elemental analysis, thermal analysis and FT-IR spectroscopy techniques. The SC-XRD analyzes of these coordination compounds showed that the first of these coordination …
Comparison Of Autologous Venous Grafts And Three Types Of Extracellular Matrix Grafts In Peyronie’S Disease Surgery, Türker Soydaş, Selman Ünal, Hali̇l Uzundal, Merve Kaşikci, Musab Ali̇ Kutluhan, Emrah Okulu, Önder Kayigi̇l
Comparison Of Autologous Venous Grafts And Three Types Of Extracellular Matrix Grafts In Peyronie’S Disease Surgery, Türker Soydaş, Selman Ünal, Hali̇l Uzundal, Merve Kaşikci, Musab Ali̇ Kutluhan, Emrah Okulu, Önder Kayigi̇l
Turkish Journal of Medical Sciences
Background/aimPeyronie's Disease (PD) is known as a wound-healing disorder, for which surgery remains the gold standard treatment, but studies comparing graft materials are few in the literature. The aim of this study is to evaluate the mid- and long-term results of patients who had Peyronie's surgery with grafting procedures performed by a single experienced surgeon, according to the graft materials.Materials and methodsPatients who underwent corporoplasty between 2014 and 2020 with grafting procedures by a single experienced surgeon were retrospectively reviewed. 115 patients were divided into 4 groups according to the graft material used: autologous saphenous venous graft, Group 1 (n=36); …
The Impact Of Maternal Muscle Strength On Cesarean Delivery Outcomes: A Comparative Study Of Nulliparous Women, Gülsemi̇n Ertürk Çeli̇k, Sezi̇n Ertürk Aksakal, Yaprak Engi̇n Üstün
The Impact Of Maternal Muscle Strength On Cesarean Delivery Outcomes: A Comparative Study Of Nulliparous Women, Gülsemi̇n Ertürk Çeli̇k, Sezi̇n Ertürk Aksakal, Yaprak Engi̇n Üstün
Turkish Journal of Medical Sciences
Arkaplan/amaçAraştırma, doğumda anne kas kütlesi ve gücü ile doğum şekli arasındaki korelasyona odaklandı. Özellikle, nullipar gebe kadınlar terimine odaklandı ve quadriceps femoris kasının ultrasonografik ölçümlerini serum miyostatin seviyeleri ve el sıkma testi ile belirlenen kas gücüyle birlikte analiz etti. Amaç, bu faktörlerin vajinal veya sezaryenle doğum yapma olasılığını etkileyip etkilemediğini ayırt etmekti.Malzemeler ve yöntemlerBu çalışma, 86 sağlıklı, doğum yapmamış kadını, doğum biçimlerine göre iki gruba ayırarak çalışmaya dahil etti: vajinal doğum (58 kadın, Grup 1) ve sezaryen (28 kadın, Grup 2). Demografik bilgiler, doğum özellikleri, quadriceps femoris'in ultrasonografik ölçümleri, uzuv çevreleri, el kavrama gücü ve serum miyostatin konsantrasyonları üzerinde karşılaştırmalı …
A Nationwide Study: Prevalence Of Rheumatoid Factor And Anti- Citrullinated Peptide Positivity And Their Contribution To Rheumatoid Arthritis Diagnosis, Hasan Satiş, Abdulsamet Erden, Emre Bi̇lgi̇n, Gi̇zem Ayan, Berkan Armağan, Duygu Tecer, Alper Sari, Umut Kalyoncu, Murat Çağlayan, Mustafa Mahi̇r Ülgü, Mustafa Okan Ayvali, Nai̇m Ata, Şuayi̇p Bi̇ri̇nci̇
A Nationwide Study: Prevalence Of Rheumatoid Factor And Anti- Citrullinated Peptide Positivity And Their Contribution To Rheumatoid Arthritis Diagnosis, Hasan Satiş, Abdulsamet Erden, Emre Bi̇lgi̇n, Gi̇zem Ayan, Berkan Armağan, Duygu Tecer, Alper Sari, Umut Kalyoncu, Murat Çağlayan, Mustafa Mahi̇r Ülgü, Mustafa Okan Ayvali, Nai̇m Ata, Şuayi̇p Bi̇ri̇nci̇
Turkish Journal of Medical Sciences
AbstractAim: Rheumatoid factor (RF) and Anti Citrullinated Peptide (anti-CCP) is specific for rheumatoid arthritis (RA) diagnosis. However they could be positive in other disease and even healthy populations. It was aimed to investigate the prevalence of positive RF and anti-CCP antibodies in persons admitted to hospital for any reason and on a national scale.Material and Method: The National Electronic Health Database, which contains the clinical records of over eighty million people, is used to design this multi-center, retrospective cohort study. The subjects included in the study were divided into age groups in 10-year periods. RA cases were identified by using …
Production And Characterization Of Zn- And Cu-Doped Y2o3–Al2o3–Sio2 (Yas) Glass Microspheres, Fatma Unal, Batur Ercan
Production And Characterization Of Zn- And Cu-Doped Y2o3–Al2o3–Sio2 (Yas) Glass Microspheres, Fatma Unal, Batur Ercan
Turkish Journal of Medical Sciences
Background/aim: YAS glass microspheres are currently used in radioembolization treatment. However, abscess formation can occur following this treatment. The aim of this study is to endow YAS glass microspheres with antibacterial properties to address the abscesses that form in patients after radioembolization treatment.Materials and methods: In this study, undoped Y2O3–Al2O3–SiO2 (YAS) glass microspheres, as well as those doped with antibacterial agents zinc (Zn) and/or copper (Cu), were successfully fabricated using a sol-gel derived method.Results: After heat treatment, the microspheres exhibited an amorphous structure. Additionally, the incorporation of Zn and/or Cu dopants did not alter the patterns observed in the X-ray …
Phthalate Exposure Induces Cell Death And Ferroptosis In Neonatal Microglial Cells, Eli̇f Keleş, Lati̇fe Arzu Aral, Zübeyi̇r Elmazoğlu, Hasan Hüseyi̇n Kazan, Eli̇f Gülçi̇çek Abbasoğlu Topa, Mehmet Ali̇ Ergün, Hayrunni̇sa Bolay
Phthalate Exposure Induces Cell Death And Ferroptosis In Neonatal Microglial Cells, Eli̇f Keleş, Lati̇fe Arzu Aral, Zübeyi̇r Elmazoğlu, Hasan Hüseyi̇n Kazan, Eli̇f Gülçi̇çek Abbasoğlu Topa, Mehmet Ali̇ Ergün, Hayrunni̇sa Bolay
Turkish Journal of Medical Sciences
Background/aim: Phthalates are the materials used for plasticizing polyvinyl chloride. Di-(2-Ethylhexyl) phthalate (DEHP) is one of the most frequently used phthalates in a wide range of applications, including medical equipment such as endotracheal and feeding tubes, intravenous catheters, central lines, extracorporeal membrane oxygenation sets, total parenteral nutrition bags, blood product sets, and intravenous pump lines, respiratory sets in neonatal intensive care units. Studies have shown that phthalates, including DEHP, can cross the placenta and blood-brain barrier, possibly leading to neurodevelopmental impairments in vitro and in vivo. However, the molecular mechanisms affected by phthalate exposure have not been explored in depth. …
Predictive Value Of Preoperative Fried Frailty Phenotype Assessment And Serum Biomarkers On The Prognosis Of Elderly Patients With Femoral Neck Fracture Under General Anesthesia Within 3 Months After Surgery, Fu Xu, Xin Kuang, Baofeng Cao, Yang Yue
Predictive Value Of Preoperative Fried Frailty Phenotype Assessment And Serum Biomarkers On The Prognosis Of Elderly Patients With Femoral Neck Fracture Under General Anesthesia Within 3 Months After Surgery, Fu Xu, Xin Kuang, Baofeng Cao, Yang Yue
Turkish Journal of Medical Sciences
Background/aim: Femoral neck fracture (FNF) seriously impact the health of the elderly and affect their long-term quality of life of the patients. This study aimed to determine whether combining the preoperative Fried Frailty Phenotype (FFP) with serum fibroblast growth factor receptor 3 (FGFR3) and run-related transcription factor 2 (RUNX2) could better predict the prognosis of elderly patients with FNF 3 months after surgery.Materials and methods: A total of 150 elderly patients with FNF (60–89 years old) were enrolled and divided into a nonfrailty cohort and a frailty cohort based on preoperative FFP evaluation. The hip recovery of patients 3 months …
Correction Of Griscelli Syndrome Type 2 Causing Mutations In The Rab27a Gene With Crispr/Cas9, Özgür Doğuş Erol, Şi̇mal Şenocak, Burcu Özçi̇men, Gülen Güney Esken, Hasan Basri̇ Kiliç, Yusuf Çeti̇n Kocaefe, Niek Peter Van Til, Fatima Aerts Kaya
Correction Of Griscelli Syndrome Type 2 Causing Mutations In The Rab27a Gene With Crispr/Cas9, Özgür Doğuş Erol, Şi̇mal Şenocak, Burcu Özçi̇men, Gülen Güney Esken, Hasan Basri̇ Kiliç, Yusuf Çeti̇n Kocaefe, Niek Peter Van Til, Fatima Aerts Kaya
Turkish Journal of Biology
Background/aimGriscelli Syndrome Type 2 (GS-2) is a rare, inherited immune deficiency caused by a mutation in the RAB27A gene. Current treatment consists of hematopoietic stem cell transplantation. Lack of suitable donors warrants the development of alternative treatment strategies, including gene therapy. The development of mutation-specific CRISPR/Cas9 gene editing technology has opened the way for custom designed gene correction of patient-derived stem cells. Here, we aimed to custom design CRISPR/Cas9 constructs and test their efficiency of homology directed repair (HDR) on the correction of exon 3 and exon 7 mutations in the RAB27A gene of GS-2 patient-derived mesenchymal stem cells (MSCs) …