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Study On Heavy Metal Content Calculation And Agricultural Potential Based On Hyperspectral Remote Sensing Image Processing, Xiangyu Shan, Fei Dou, Shuangquan Gao, Chuanping Liu, Cangbai Li
Study On Heavy Metal Content Calculation And Agricultural Potential Based On Hyperspectral Remote Sensing Image Processing, Xiangyu Shan, Fei Dou, Shuangquan Gao, Chuanping Liu, Cangbai Li
Turkish Journal of Agriculture and Forestry
Soil is the main influencing factor for plant growth, reproduction, and distribution. With the acceleration of industrialization and the intensification of human activities, the problem of heavy metal pollution in agricultural soil is becoming increasingly prominent. Heavy metals in soil are toxic and easily absorbed by plants, and consuming contaminated crops poses a great threat to human health. Therefore, it is necessary to monitor the content of heavy metals (HMs for short here) in soil. Hyperspectral Remote Sensing (HRS for short here) has great application prospects in obtaining quantitative information of soil organic matter, minerals and other components due to …
In-Silico Analysis For Structural And Functional Characterization Of Phosphorus-Starvation Tolerance 1 (Pstol1) Gene, Quratulain Mehdi Khan, Muhammad Aqeel, Maryam Murtaza, Wajya Ajmal, Muhammad Uzair, Sajid Fiaz, Kotb A. Attia, Asmaa M. Abushady, Itoh Kimiko, Muhammad Ramzan Khan, Ghulam Muhammad Ali
In-Silico Analysis For Structural And Functional Characterization Of Phosphorus-Starvation Tolerance 1 (Pstol1) Gene, Quratulain Mehdi Khan, Muhammad Aqeel, Maryam Murtaza, Wajya Ajmal, Muhammad Uzair, Sajid Fiaz, Kotb A. Attia, Asmaa M. Abushady, Itoh Kimiko, Muhammad Ramzan Khan, Ghulam Muhammad Ali
Turkish Journal of Agriculture and Forestry
As an important macro element for all living cells, phosphorus is essential in agricultural production systems as well and is required in large quantities by elite varieties of crops to maintain yields. Approximately 70% of worldwide cultivated land suffers from phosphorous deficiency, and it has recently been estimated that worldwide phosphorous resources will be shattered by the end of this century thus increasing the demand for crops to be more efficient in their P usage. A greater understanding of how plants can maintain yield with lower phosphorous availability is highly desirable to both breeders and farmers, therefore, significant to develop …
Enhancing Grain Yield, Oil Content, Fatty Acid Composition And Changes In Antioxidant Properties Of Camelina Using Wi-Fi Radiation, Maryam Khashayarfard, Sedigheh Arbabian, Danial Kahrizi, Fariba Sharifnia
Enhancing Grain Yield, Oil Content, Fatty Acid Composition And Changes In Antioxidant Properties Of Camelina Using Wi-Fi Radiation, Maryam Khashayarfard, Sedigheh Arbabian, Danial Kahrizi, Fariba Sharifnia
Turkish Journal of Agriculture and Forestry
Exposure to electromagnetic radiation (ER) with radio frequency is one of the environment's most common and fastest-growing human factors. Therefore, due to the increasing global growth of telecommunication towers and Wi-Fi waves, the possibility of positive or negative effects of Wi-Fi electromagnetic waves (WEW) is essential for the quality and quantity parameters of plants. An experiment was was carried out during the years 2020-2021 at the Research Farm of Tarbiat Modares University to investigate the effect of WEW on the grain yield, fatty acid composition (FA), oil content and antioxidant properties of camelina. Seeds were exposed to Wi-Fi electromagnetic radiation …
Chitosan Application Improves Yield And Quality Of Rocket (Eruca Sativa), Ayşe Özkan, Hali̇me Ünlü
Chitosan Application Improves Yield And Quality Of Rocket (Eruca Sativa), Ayşe Özkan, Hali̇me Ünlü
Turkish Journal of Agriculture and Forestry
The present study aimed to investigate the effects of chitosan application on the yield and quality of rockets. “Bengi” rocket variety was used as a plant material and chitosan was applied to leaves at four different doses (0 (control)–75–150–300 ppm). The results revealed that the yield values varied between 1691–1914 g m-2, plant height between 24.33–27.92 cm, and leaf width between 4.56–5.71 cm among the applications. The total dry matter, chlorophyll, total phenolics, vitamin C, and antiradical activity values were determined to range between 7.71% and 8.68%, 34.15 and 36.68 SPAD, 104.67 and 180.84 mg 100 g–1, 126.63 and 143.51 …
Antioxidant Properties And Aldose Reductase Inhibitory Potency Of Viscum Album L. Extracts: Experimental And Computational Insights, Bilal Akyüz, Bülent Şengül
Antioxidant Properties And Aldose Reductase Inhibitory Potency Of Viscum Album L. Extracts: Experimental And Computational Insights, Bilal Akyüz, Bülent Şengül
Turkish Journal of Agriculture and Forestry
This study systematically investigates the antioxidant capacity and inhibitory impact of Viscum album L. plant extracts on the aldose reductase (AR) enzyme through a combined approach of in vitro and in silico methods. Various sections derived from distinct plant parts were examined, revealing potent inhibitory potential. Notably, the methanol extract sourced from the plant's stem displayed remarkable efficacy with an IC50 value of 0.156 µM. Total phenolic content and antioxidant capacity analyses were conducted, highlighting variations across plant parts and solvent types. Qualitative and quantitative phenolic compounds content in the extracts was also elucidated by LC-MS/MS analysis and it was …
Dorycnium Vuralii (Fabaceae), A New Species From Türkiye, Bilal Şahi̇n, Seher Karaman, Mevlüde Alev Ateş, Zeki Aytaç
Dorycnium Vuralii (Fabaceae), A New Species From Türkiye, Bilal Şahi̇n, Seher Karaman, Mevlüde Alev Ateş, Zeki Aytaç
Turkish Journal of Botany
The present study describes a new species Dorycnium vuralii (Fabaceae) from Çankırı, Türkiye. The new species is compared morphologically to the taxa of sect. Bonjeanea and sect. Dorycnium along with pollen micromorphology, leaflet, and seed micromorphology. The geographical distribution of Dorycnium vuralii is mapped. The phylogenetic relationships between the new species and other closely related species in the genus are inferred based on DNA data from both cpDNA and nrDNA (rbcL1&ITS). Although phylogenetic implications are different in the two DNA barcoding regions, D. vuralii is shown to be a new species in both molecular data. The new species is assessed …
Identification Of Carrying Alien Dna Fragments In Solanum Melongena X Solanum Incanum Interspecific Progeny By Using Cosii Marker, Görkem Sülü, İlknur Polat, Hati̇ce Fi̇li̇z Boyaci, Ahmet Naci̇ Onus
Identification Of Carrying Alien Dna Fragments In Solanum Melongena X Solanum Incanum Interspecific Progeny By Using Cosii Marker, Görkem Sülü, İlknur Polat, Hati̇ce Fi̇li̇z Boyaci, Ahmet Naci̇ Onus
Turkish Journal of Botany
Cultivated eggplant (Solanum melongena L.) is produced in many countries with temperate and tropical climates and has great economic importance. In recent years, resistance to biotic and abiotic stress conditions in addition to increasing yield and quality has gained importance in plant breeding including eggplant breeding. Therefore, the wild relative S. incanum is an important parent in breeding studies as it provides resistance to some important biotic and abiotic stresses for eggplant. It is possible to obtain a fully fertile hybrid between the two species, as well as to establish F2 lines. However, it is a mystery whether there is …
Isolation And Assessment Of Halophilic Rhizobacteria Plant Growth-Promoting Traits For Alleviating Salt Stress In Wheat, Alev Sezen, Ömer Faruk Algur, Ferruh Aşçi, Arzu Ünal
Isolation And Assessment Of Halophilic Rhizobacteria Plant Growth-Promoting Traits For Alleviating Salt Stress In Wheat, Alev Sezen, Ömer Faruk Algur, Ferruh Aşçi, Arzu Ünal
Turkish Journal of Botany
In this study, 22 halophilic bacteria were isolated from plants collected together with rhizosphere soil from habitats with high salt content in and around Erzurum. Various plant growth-promoting (PGP) properties of these isolates (nitrogen fixing, phosphate solubilizing, ACC deaminase, and IAA and siderephore production) were determined. Bacteria positive for PGP properties and various combinations with these bacteria were subjected to pot experiments in saline medium (greenhouse conditions) and their effects on growth parameters (root and stem length, fresh and dry weight, protein, and chlorophyll and carotenoid content) of wheat plants were determined. As a result of the research, the isolates …
A New Permineralized Corypha-Type Coryphoid Palm Stem From K-Pg Of India: Anatomy, Systematics, Saprophytic Fungi, And Paleoecology, Ashif Ali, Kaustav Roy, Biswajit Mukherjee, Subir Bera, Mahasin Khan
A New Permineralized Corypha-Type Coryphoid Palm Stem From K-Pg Of India: Anatomy, Systematics, Saprophytic Fungi, And Paleoecology, Ashif Ali, Kaustav Roy, Biswajit Mukherjee, Subir Bera, Mahasin Khan
Turkish Journal of Botany
Palms are known to be an important and diverse angiosperm component in the Deccan Intertrappean beds of Central India. However, the report of fossilized palm stems inhibiting saprophytic fungal remains is empty in the field of paleobotany. Here, we document for the first time the occurrence of fungal remains in a petrified palm stem collected from the latest Maastrichtian (Late Cretaceous)-earliest Danian (early Paleocene) sediments of the Deccan Intertrappean beds of Madhya Pradesh, Central India. The anatomical features of the fossil stem are characterized by the presence of Corypha-type general stem pattern (progressive decrease of fibrous parts of fibrovascular bundles, …
Coastal Discharge Extremes And Their Environmental Impact On The Sea Of Marmara, Nüvi̇t Berkay Başdurak
Coastal Discharge Extremes And Their Environmental Impact On The Sea Of Marmara, Nüvi̇t Berkay Başdurak
Turkish Journal of Earth Sciences
Increases in evaporation driven by global warming change the hydrological cycle by fueling extreme precipitation and exacerbating the frequency and intensity of extreme floods. Combined with the increase in terrestrial waste and pollutants, the changing climate exposes coastal zones to natural hazards. The Sea of Marmara, as an inland sea with a dense coastal population, is more vulnerable to such changes and subject to eutrophication and extreme environmental events (e.g., mucilage). Therefore, quantification of daily and along-coast variation of river discharge and evaluation of its annual trend of extremes are crucial. The daily discharges from the coastal watersheds Biga, Gönen, …
Consensus-Based Virtual Leader Tracking Algorithm For Flight Formation Control Of Swarm Uavs, Berat Yıldız, Akif Durdu, Ahmet Kayabaşi
Consensus-Based Virtual Leader Tracking Algorithm For Flight Formation Control Of Swarm Uavs, Berat Yıldız, Akif Durdu, Ahmet Kayabaşi
Turkish Journal of Electrical Engineering and Computer Sciences
Technological developments in industrial areas also impact unmanned aerial vehicles (UAVs). Recent improvements in both software and hardware have significantly increased the use of many UAVs in social and military fields. In particular, the widespread use of these vehicles in social areas such as entertainment, shipping, transportation, and delivery and military areas such as surveillance, tracking, and offensive measures has accelerated the research on swarm systems. This study examined the previous investigations on swarm UAVs and aimed to create a more efficient algorithm. The effectiveness of the proposed algorithm was compared with other leader-based applications. A swarm consisting of 5 …
Atomic Comagnetometer Gyroscopes For Inertial Navigation Systems: A Review, Murat Salim Karabinaoglu, Bekir Çakir, Mustafa Engin Başoğlu
Atomic Comagnetometer Gyroscopes For Inertial Navigation Systems: A Review, Murat Salim Karabinaoglu, Bekir Çakir, Mustafa Engin Başoğlu
Turkish Journal of Electrical Engineering and Computer Sciences
In recent years, developments in quantum sensing, laser, and atomic sensor technologies have also enabled advancement in the field of quantum navigation. Atomic-based gyroscopes have emerged as one of the most critical atomic sensors in this respect. In this review, a brief technology statement of spin exchange relaxation free (SERF) and nuclear magnetic resonance (NMR) type atomic comagnetometer gyroscope (CG) is presented. Related studies in the literature have been gathered, and the fundamental compositions of CGs with technical basics are presented. A comparison of SERF and NMR CGs is provided. A basic simulation of SERF CG was carried out because …
Advanced Hyperthermia Treatment: Optimizing Microwave Energy Focus For Breast Cancer Therapy, Burak Acar, Tuba Yilmaz Abdolsaheb, Ali Yapar
Advanced Hyperthermia Treatment: Optimizing Microwave Energy Focus For Breast Cancer Therapy, Burak Acar, Tuba Yilmaz Abdolsaheb, Ali Yapar
Turkish Journal of Electrical Engineering and Computer Sciences
This paper presents a fast antenna phase optimization scheme to enable microwave power focusing for breast cancer hyperthermia. The power focusing is achieved through the maximization of the deposited electric field on the target malignant tumor tissue. To do so, a malignant breast tumor, the surrounding breast medium, and the skin of the breast are modeled as a cylindrical structure composed of eccentric cylinders, and electric field distribution is computed analytically in terms of cylindrical harmonics. This approach minimized the computational cost and simplified the breast medium model. To ensure applicability across various breast types, the dielectric properties (DPs) of …
On The Reconstruction Of An Integro-Differential Dirac Operator With Parameter-Dependent Nonlocal Integral Boundary Conditions From The Nodal Data, Baki Keskin, Yu Ping Wang
On The Reconstruction Of An Integro-Differential Dirac Operator With Parameter-Dependent Nonlocal Integral Boundary Conditions From The Nodal Data, Baki Keskin, Yu Ping Wang
Turkish Journal of Mathematics
We consider the integro-differential Dirac operator with parameter-dependent nonlocal integral boundary conditions. We derive the asymptotic expressions for the eigenvalues and the zeros of eigenfunctions (nodal points or nodes) and develop a constructive procedure for solving the inverse nodal problem for this operator.
Description Of A New Species (Eucypris Dorlionensis N. Sp.) (Ostracoda, Crustacea)From Türkiye And A Cladistic Analysis Of The Genus Eucypris, Fi̇li̇z Batmaz, Mehmet Yavuzatmaca, Okan Külköylüoğlu
Description Of A New Species (Eucypris Dorlionensis N. Sp.) (Ostracoda, Crustacea)From Türkiye And A Cladistic Analysis Of The Genus Eucypris, Fi̇li̇z Batmaz, Mehmet Yavuzatmaca, Okan Külköylüoğlu
Turkish Journal of Zoology
This is the first clustering analysis of the 53 species of the genus Eucypris where we used 28 plesiomorphic and apomorphic character states in the Winclada/NONA program. Accordingly, Eucypris dorlionensis n. sp. was clustered within Group 2, in which the new species was clearly separated from the other species of the genus based on the shape of the carapace, presence of fine hair-like setae on the carapace surface, the position of the maximum height of the carapace, and length ratio of terminal claws of the second antenna. Eucypris dorlionensis n. sp. was collected from a trough in Eskişehir province in …
The Length-Weight Relationship And Condition Factors Of Coastal Small-Sized Adult And Juvenile Fish Species Following Dense Mucilage In The Sea Of Marmara, Türkiye, Yusuf Şen, İsmail Burak Daban, Alkan Özteki̇n, Adnan Ayaz, Uğur Altınağaç, Ali İşmen, Ahsen Yüksek, Uğur Özeki̇nci̇, Fikret Çakır, Tekin Demi̇rkiran, Gençtan Erman Uğur, Oğuzhan Ayaz, Buminhan Burkay Selçuk
The Length-Weight Relationship And Condition Factors Of Coastal Small-Sized Adult And Juvenile Fish Species Following Dense Mucilage In The Sea Of Marmara, Türkiye, Yusuf Şen, İsmail Burak Daban, Alkan Özteki̇n, Adnan Ayaz, Uğur Altınağaç, Ali İşmen, Ahsen Yüksek, Uğur Özeki̇nci̇, Fikret Çakır, Tekin Demi̇rkiran, Gençtan Erman Uğur, Oğuzhan Ayaz, Buminhan Burkay Selçuk
Turkish Journal of Zoology
To understand the ecosystem health of the Sea of Marmara following the dense mucilage event in 2021, growth indicators (length-weight relationships and condition factors) of coastal fish species were investigated. For this purpose, individuals were sampled during experimental fishing trials with beach seine nets between November 2021 and March 2022 from the Sea of Marmara, Türkiye. A total of 32 fish species belonging to 19 families were obtained. A total of 12 juvenile and 20 small-sized adult coastal fish species were identified, condition factors and length-weight relationships (LWRs) were calculated. The LWR results of this study reveal first findings as …
Highways For Red Wood Ants (Hymenoptera: Formicidae): A New Method To Increase The Size Of Anthills, Stanislav Stukalyuk, Mykola Kozyr
Highways For Red Wood Ants (Hymenoptera: Formicidae): A New Method To Increase The Size Of Anthills, Stanislav Stukalyuk, Mykola Kozyr
Turkish Journal of Zoology
Red wood ants (RWA, Formica rufa group) play a key role in forest ecosystems as effective entomophages and participants in the circulation of organic matter. The aim of our study was to evaluate the efficiency of using the highway method to accelerate the growth of anthills, specifically focusing on height, diameter, volume. The study was conducted in Kyiv, Ukraine, from May to October 2023. In the experimental group, highways were constructed on ant trails, totalling nine Formica polyctena Forster, 1850 anthills and eight Formica rufa Linnaeus, 1761 anthills. These highways consisted of a continuous line of logs ranging from 10 …
Inbreeding Tolerance In Two Isolated Populations Of Harting’S Vole Microtus Hartingi(Rodentia, Arvicolinae), Tanya Zorenko, Larisa Petra Kaija
Inbreeding Tolerance In Two Isolated Populations Of Harting’S Vole Microtus Hartingi(Rodentia, Arvicolinae), Tanya Zorenko, Larisa Petra Kaija
Turkish Journal of Zoology
The adaptive effects of inbreeding are understudied, but accumulating evidence suggests that it plays a major adaptive role in speciation, as populations with a history of inbreeding are more prone to it. Differences in inbreeding tolerance in two populations of Microtus hartingi voles were studied through a series of experiments on reproductive behaviour and partner choice. Modelling an artificial polygyny via the formation of trios composed of a brother, sister, and an unrelated female has shown an uneven attitude towards inbreeding, which was closely linked to the reproduction strategy: voles of the Rhodopean population (RP) would reproduce communally with only …
Tnfr1 Signaling Is Positively Regulated By Jak-2 And C-Src Via Tyrosine Phosphorylation, Fatma Zehra Hapi̇l Zevkli̇ler, Fatma Ece Çopuroğlu, Mustafa Gökhan Ertosun, Ufuk Mert, Derya Özeş, Osman Nidai Özeş
Tnfr1 Signaling Is Positively Regulated By Jak-2 And C-Src Via Tyrosine Phosphorylation, Fatma Zehra Hapi̇l Zevkli̇ler, Fatma Ece Çopuroğlu, Mustafa Gökhan Ertosun, Ufuk Mert, Derya Özeş, Osman Nidai Özeş
Turkish Journal of Biology
Background/aim: Tumor necrosis factor alpha (TNFα, a.k.a. TNF) is a pleiotropic cytokine that exerts most of its effects through type 1 TNF receptor (TNFR1). Following TNF binding, TNFR1 recruits TRADD (tumor necrosis factor receptor type 1-associated DEATH domain). This interaction triggers formation of signalosome complexes which have been claimed to induce apoptosis (via downstream caspase activations), inflammation (via NF-kappaB) and stress pathways (JNK & p38). However, the mechanism underlying TNF-induced ERK and AKT activation is not completely revealed. TNFR1 is known to constitutively bind c-Src and JAK2, and these enzymes were previously demonstrated to modulate TNF signaling. Therefore, we hypothesized …
Prognostic Gene Biomarkers For C-Src Inhibitor Si162 Sensitivity In Melanoma Cells, Seyhan Türk, Ayşegül Yilmaz, Ümit Yavuz Malkan, Gülberk Uçar, Can Türk
Prognostic Gene Biomarkers For C-Src Inhibitor Si162 Sensitivity In Melanoma Cells, Seyhan Türk, Ayşegül Yilmaz, Ümit Yavuz Malkan, Gülberk Uçar, Can Türk
Turkish Journal of Biology
Background/aim: Early detection and treatment are crucial in combating malignant melanoma. Src is an important therapeutic target in melanoma due to its association with cancer progression. However, developing effective Src-targeting drugs remains challenging and personalized medicine relies on biomarkers and targeted therapies for precise and effective treatment. This study focuses on Si162, a newly synthesized c-Src inhibitor, to identify reliable biomarkers for predicting Si162 sensitivity and explore associated biological characteristics and pathways in melanoma cells. Materials and methods: Primary melanoma cells (M1, M21, M24, M84, M133, M307, and M2025) were obtained from patients diagnosed with melanoma. Si162 cytotoxicity tests were …
Expression Patterns Of M6a Rna Methylation Regulators Under Apoptotic Conditions In Various Human Cancer Cell Lines, Azime Akçaöz Alasar, Buket Sağlam, İpek Erdoğan Vatansever, Bünyamin Akgül
Expression Patterns Of M6a Rna Methylation Regulators Under Apoptotic Conditions In Various Human Cancer Cell Lines, Azime Akçaöz Alasar, Buket Sağlam, İpek Erdoğan Vatansever, Bünyamin Akgül
Turkish Journal of Biology
Background/aim: Cancer is a complex disease that involves both genetic and epigenetic factors. While emerging evidence clearly suggests that changes in epitranscriptomics play a crucial role in cancer pathogenesis, a comprehensive understanding of the writers, erasers, and readers of epitranscriptomic processes, particularly under apoptotic conditions remains lacking. The aim of this study was to uncover the changes in the expression of m6A RNA modifiers under apoptotic conditions across various cancer cell lines. Materials and methods: Initially, we quantified the abundance of m6A RNA modifiers in cervix (HeLa and ME180), breast (MCF7 and MDA-MB-231), lung (A549 and H1299), and colon (CaCo2 …
Circrna Ldlr Promotes Proliferation And Aerobic Glycolysis Of Gastric Cancer Cells By Targeting Chd1 With Mir-449b-5p, Fanye Zeng, Juntao Zhao, Mengting Tong, Wenting He, Nan Li, Yuxiang Fan, Yanhua Zhu, Liping Zhang, Hongliang Zhang
Circrna Ldlr Promotes Proliferation And Aerobic Glycolysis Of Gastric Cancer Cells By Targeting Chd1 With Mir-449b-5p, Fanye Zeng, Juntao Zhao, Mengting Tong, Wenting He, Nan Li, Yuxiang Fan, Yanhua Zhu, Liping Zhang, Hongliang Zhang
Turkish Journal of Biology
Background/aim: Circular RNAs can serve as detection biomarkers and therapeutic targets for tumors. Our study aimed to elucidate the mechanisms associated with circRNA LDLR (circLDLR) in gastric cancer (GC) proliferation and aerobic glycolysis. Materials and methods: Expression signatures of circLDLR, miR-449b-5p, and CHD1 were examined in GC samples using quantitative PCR. Proliferation ability of MKN-45 cells was assessed via CCK-8 and EdU assays, and cell apoptosis was measured by flow cytometry. Glucose uptake, lactate production, ATP/ADP ratios, and NAD+/NADH ratios in cell supernatants were quantified to evaluate aerobic glycolysis. Subcellular isolation assay, quantitative PCR, immunoblot analysis, RNA immunoprecipitation (RIP), and …
Beneficial Effects Of A Novel Polyherbal Formulation On The Skeletal Muscle Antioxidant Status, Inflammation, And Muscle-Signaling Proteins In Exercised Rats, Mehmet Tuzcu, Oğuzhan Özdemi̇r, Cemal Orhan, Nurhan Şahi̇n, Abhijeet Morde, Muralidhara Padigaru, Prakash Bhanuse, Kazım Şahi̇n
Beneficial Effects Of A Novel Polyherbal Formulation On The Skeletal Muscle Antioxidant Status, Inflammation, And Muscle-Signaling Proteins In Exercised Rats, Mehmet Tuzcu, Oğuzhan Özdemi̇r, Cemal Orhan, Nurhan Şahi̇n, Abhijeet Morde, Muralidhara Padigaru, Prakash Bhanuse, Kazım Şahi̇n
Turkish Journal of Biology
Background/aim: Exhausting exercise can damage muscle tissue due to free radical interactions. It is hypothesized that the increase in free radicals following muscle injury, either due to oxidative damage to biomolecules or the activation of inflammatory cytokines, may lead to secondary muscle damage. This study investigated the effects of a novel joint health formula (JHF) containing bisdemethoxycurcumin-enriched curcumin, 3-O-Acetyl-11-keto-beta-boswellic acid-enriched Boswellia (AKBA), and Ashwagandha on exhaustion time, grip strength, antioxidant status, and muscle-signaling proteins in exhaustively exercised rats. Materials and methods: Twenty-eight rats were divided into four groups: Control (C), exercise (E), E + JHF 100 (100 mg/kg), and E …
Effect Of Thymol On Oxidative Stress And Reelin Signaling Pathway In Alzheimer's Disease Model, Barış Bi̇tmez, Burcu Çevreli̇, Emel Kaşikçi
Effect Of Thymol On Oxidative Stress And Reelin Signaling Pathway In Alzheimer's Disease Model, Barış Bi̇tmez, Burcu Çevreli̇, Emel Kaşikçi
Turkish Journal of Biology
Background/aim: The purpose of this study was to investigate how thymol affects cognitive functions and the levels of MDA, GSH, Aβ1-42, ApoE, reelin, and LRP8 in an AD model induced in male Wistar albino rats with the application of D-galactose (D-gal) and aluminum chloride (AlCl3). Materials and methods: In this work, 3-month-old male Wistar albino rats were used. Group 1 served as the Control, Group 2 received 0.5 mL/day saline + 0.5 mL/day sunflower oil, Group 3 was administered 200 mg/kg/day AlCl3 + 60 mg/kg/day D-gal, Group 4 received 30 mg/kg/day thymol, and Group 5 was administered 200 mg/kg/day AlCl3 …
Divergent Proteomic Profiles Of Opium Poppy Cultivars, Setenay Aykanat, Mine Türktaş
Divergent Proteomic Profiles Of Opium Poppy Cultivars, Setenay Aykanat, Mine Türktaş
Turkish Journal of Biology
We examined the proteomic profiles of three registered opium poppy cultivars (Papaver somniferum L.) having different alkaloid contents. The study was conducted on both the stem and capsule organs. A high number of differentially expressed proteins (DEPs) were identified between the cultivars and the organs. We analyzed DEPs for their contribution in GO terms and KEGG pathways. The up-regulated DEPs were significantly enriched in photosynthesis and translation, for morphine-rich and noscapine-rich cultivars, respectively. The data depicted that photosynthesis is crucial for Benzylisoquinoline alkaloid (BIA) biosynthesis, but different processes are also effective on morphine and noscapine biosynthesis, which occur at different …
Theranostic Potential Of A Novel Aptamer Specifically Targeting Her2 In Breast Cancer Cells, Fulya Küçükcankurt, Samet Uçak, Nedret Altiok
Theranostic Potential Of A Novel Aptamer Specifically Targeting Her2 In Breast Cancer Cells, Fulya Küçükcankurt, Samet Uçak, Nedret Altiok
Turkish Journal of Biology
Background/aim: The overexpression of HER2 is correlated with poorer outcomes and therapeutic resistance in breast cancer patients. While HER2-targeted therapies have shown improvement, prognosis remains poor for HER2-positive breast cancer patients, and these treatments have limitations. Therefore, it is crucial to explore effective molecular strategies for early detection and treatment of HER2-positive breast cancers. Materials and methods: In this study, we employed the cell-SELEX method to generate a selective aptamer capable of recognizing HER2 in its native conformation within breast cancer cells, for theranostic applications. Utilizing an adherent cell-SELEX approach, we developed and explored a DNA aptamer, named HMAP7, which …