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Lead-Induced Cytotoxicity And Mutagenicity In Grass Pea, Girjesh Kumar, Ritambhara Tripathi
Lead-Induced Cytotoxicity And Mutagenicity In Grass Pea, Girjesh Kumar, Ritambhara Tripathi
Turkish Journal of Biology
Chromosomal variation is an important tool in genetic analysis. The objectives of the present study were to determine the mutagenic potential of lead (Pb) on the meiotic cells of grass pea (Lathyrus sativus) and to determine the maximum concentration of lead nitrate that induces maximum genetic variability in grass pea. The different concentrations of lead nitrate used were 25, 50, 100, 200, and 300 ppm. The percentage of abnormalities increased with the lead nitrate concentration. Different types of chromosomal abnormalities were observed, such as condensed bivalents, secondary association, laggards, bridges, cytomixis, stickiness, etc.
Soil Salinity Alters Growth, Chlorophyll Content, And Secondary Metabolite Accumulation In Catharanthus Roseus, Cheruth Abdul Jaleel, Beemarao Sankar, Ramalingam Sridharan, Rajaram Panneerselvam
Soil Salinity Alters Growth, Chlorophyll Content, And Secondary Metabolite Accumulation In Catharanthus Roseus, Cheruth Abdul Jaleel, Beemarao Sankar, Ramalingam Sridharan, Rajaram Panneerselvam
Turkish Journal of Biology
The effect of salinity on growth, photosynthetic pigment content, and alkaloid secondary metabolite accumulation were studied in an economically important medicinal plant, Catharanthus roseus (L.) G. Don., under pot culture conditions. Plants were treated with different concentrations of NaCl, (e.g. 50 and 100 mM) 30, 45, 60, and 75 days after sowing (DAS). The plants were uprooted randomly 90 DAS to analyse growth, and chlorophyll and alkaloid content. Salinity affected all the morphological parameters and decreased growth performance. At low salinity regimes, a slight decrease was noted in chlorophyll a and b, and total chlorophyll content, but under high salinity …
Cropping Effects On Microbial Population And Nitrogenase Activity In Saline Arid Soil, Dilfuza Egamberdieva, Zulfiya Kucharova
Cropping Effects On Microbial Population And Nitrogenase Activity In Saline Arid Soil, Dilfuza Egamberdieva, Zulfiya Kucharova
Turkish Journal of Biology
Soil salinization is a major problem in irrigated agriculture. A field study was conducted in the Sariosiyo district in the Surkhandarya region of southeast Uzbekistan to evaluate soil nitrogenase activity and nitrogen-fixing bacteria populations in saline serozem soils under wheat, maize, and alfalfa, as well as from adjacent fallow land. Composite soil samples were randomly collected from depths of 0-10, 10-20, and 20-30 cm in autumn, winter, spring, and summer, which were then 2-mm sieved and subjected to selected microbial population analysis and enzymatic studies. The results showed that alfalfa contributed both to high nitrogenase activity and to a large …
Improvement Of The Nutritional Value Of Soybean [Glycine Max (L) Merr.] Seed With Alteration In Protein Subunits Of Glycinin (11s Globulin) And \Beta-Conglycinin (7s Globulin), Behzad Kaviani, Ardashir Kharabian
Improvement Of The Nutritional Value Of Soybean [Glycine Max (L) Merr.] Seed With Alteration In Protein Subunits Of Glycinin (11s Globulin) And \Beta-Conglycinin (7s Globulin), Behzad Kaviani, Ardashir Kharabian
Turkish Journal of Biology
Protein quality in soybean seeds is strongly influenced by nutritional conditions. Glycinin (11S globulin) and \beta-conglycinin (7S globulin) are the 2 main proteins in soybean seeds. Protein quality of glycinin (11S) is higher than that of \beta-conglycinin (7S), due to the presence of higher amounts of s-containing amino acids (methionine and cysteine) in glycinin than \beta-conglycinin. Of the amino acids in glycinin, 3%-4.5% are methionine and cysteine but these important amino acids are not found in \beta-conglycinin (especially \beta-subunit). Pot studies were conducted with soybean [Glycine max (L) Merr.] grown under various levels of KCl and CaHPO4 and the effects …
Evaluation Of Antioxidant And Antimicrobial Activity Of Seaweed (Sargassum Sp.) Extract: A Study On Inhibition Of Glutathione-S-Transferase Activity, Jayanta Kumar Patra, Sakti Kanta Rath, Karmabeer Jena, Vijaya Kumar Rathod, Hrudayanath Thatoi
Evaluation Of Antioxidant And Antimicrobial Activity Of Seaweed (Sargassum Sp.) Extract: A Study On Inhibition Of Glutathione-S-Transferase Activity, Jayanta Kumar Patra, Sakti Kanta Rath, Karmabeer Jena, Vijaya Kumar Rathod, Hrudayanath Thatoi
Turkish Journal of Biology
In the present study, the free radical scavenging potentials (DPPH radical and hydroxyl radical), inhibition of lipid peroxidation, and glutathione-S-transferase and antimicrobial properties of Sargassum sp. extract were investigated. The tested extract exhibited a dose-dependent free radical scavenging action against DPPH radical and hydroxyl radical and antimicrobial activity. In addition, inhibition of lipid peroxidation and glutathione-S-transferase activities were also observed. The overall results have established that this seaweed could be used against several diseases and, in the food processing industry, to preserve foods.
Sensitivity Of Kinetoplastids To Aminoglycoside: Correlation With The 3’ Region Of The Small Subunit Rrna Gene, A. S. Hamad Elgazwy, Masoom M. Yasinzai
Sensitivity Of Kinetoplastids To Aminoglycoside: Correlation With The 3’ Region Of The Small Subunit Rrna Gene, A. S. Hamad Elgazwy, Masoom M. Yasinzai
Turkish Journal of Biology
In vitro culture systems were used to assess the growth inhibition of kinetoplastids by a variety of aminoglycosides. The parasites were allowed to grow to the stationary phase in the presence of varying concentrations of the drugs. The IC-50 for every drug was calculated by comparison with the control. The sensitivity of various leishmanial strains to these drugs was in the order of: G418 > hygromycin > paromomycin > neomycin; however, under our assay conditions gentamycin and kanamycin were non-leishmanicidal. The effects of the drugs on the intracellular form of the parasite in the macrophage cell line were also tested. Other kinetoplastids, such …
The Effect Of Hyperosmotic Stress And Nitrogen Starvation On Growth And \Beta-Galactosidase Synthesis In Kluyveromyces Lactis And Kluyveromyces Marxianus, Sezai̇ Türkel, Eli̇f Arik, Si̇nem Güzelvardar
The Effect Of Hyperosmotic Stress And Nitrogen Starvation On Growth And \Beta-Galactosidase Synthesis In Kluyveromyces Lactis And Kluyveromyces Marxianus, Sezai̇ Türkel, Eli̇f Arik, Si̇nem Güzelvardar
Turkish Journal of Biology
Kluyveromyces lactis and Kluyveromyces marxianus are industrial yeasts widely used in the production of the \beta-galactosidase enzyme. Biosynthesis of \beta-galactosidase is controlled by glucose repression. In this study it was demonstrated that the derepression of \beta-galactosidase biosynthesis in these yeast strains is inhibited by high osmotic stress. It was found that the \beta-galactosidase activity of K. lactis and K. marxianus remained approximately at the repressed level when these yeast cells were subjected to NaCl-, KCl-, or sucrose-induced high osmotic stress. Derepression of \beta-galactosidase biosynthesis seems to be more sensitive to high osmotic stress in K. marxianus than in K. lactis. …
Comparative Antioxidant Activity Of Some Edible Plants, Zaha A. El-Agbar, Ashok K. Shakya, Nooman A. Khalaf, Makbula Al-Haroon
Comparative Antioxidant Activity Of Some Edible Plants, Zaha A. El-Agbar, Ashok K. Shakya, Nooman A. Khalaf, Makbula Al-Haroon
Turkish Journal of Biology
Terminalia chebula, Salvia officinalis L., Calamintha incana, Thymus vulgaris L., Matricaria chamomilla, and Nigella sativa are commonly used spices. In the present study the methanolic extracts of these spices were evaluated for their antioxidant activity by the 1,1-diphenyl-2-picryl-hydrazyl (DPPH) free radical scavenging method. All the methanolic extracts showed significant antioxidant activity. The IC_{50} of the methanolic extracts ranged between 3.8 ± 0.1 and 168.8 ± 2.1 \mug/ml, and that of ascorbic acid was 8.6 ± 0.1 \mug/ml. The study revealed that the consumption of these spices could exert several beneficial effects by virtue of their antioxidant activity.
The Antioxidant Activity Of Some Medicinal Plants, Prateek Kumar Jain, Veerasamy Ravichandran, Simant Sharma, Ram. K. Agrawal
The Antioxidant Activity Of Some Medicinal Plants, Prateek Kumar Jain, Veerasamy Ravichandran, Simant Sharma, Ram. K. Agrawal
Turkish Journal of Biology
The antioxidant properties of the methanol extracts of 10 medicinal plants were evaluated with the DPPH (1,1-diphenyl-2-picryl hydrazyl) test, hydroxyl scavenging test, and lipid peroxidation assay. The methanol extract of Emblica officinalis was the most active according to the DPPH test, with an IC_{50} value of 7.92 ± 0.1 \mug/ml, followed by Asparagus racemosus, with an IC_{50} value of 9.28 ± 0.2 \mug/ml. The minimum free radical scavenging activity was shown by Zingiber officinale, with an IC_{50} value of 44.48 ± 1.8 \mug/ml. The hydroxyl radical scavenging activity of the methanolic extracts of various plants was as follows: Asparagus racemosus …
Antioxidant And Vasorelaxant Activities Of Flavonoids From Amygdalus Lycioides Var. Horrida, Hossein Babaei, Omid Sadeghpour, Lutfun Nahar, Abbas Delazar, Hossein Nazemiyeh, Mohammad Reza Mansouri, Naser Poursaeid, Solmaz Asnaashari, Sedigheh Bamdad Moghadam, Satyajit Dey Sarker
Antioxidant And Vasorelaxant Activities Of Flavonoids From Amygdalus Lycioides Var. Horrida, Hossein Babaei, Omid Sadeghpour, Lutfun Nahar, Abbas Delazar, Hossein Nazemiyeh, Mohammad Reza Mansouri, Naser Poursaeid, Solmaz Asnaashari, Sedigheh Bamdad Moghadam, Satyajit Dey Sarker
Turkish Journal of Biology
Amygdalus lycioides var. horrida (Spach) Browicz (Rosaceae), also known as Prunus lycioides (Spach.) Schneid., is an endemic Iranian species of the genus Amygdalus. In Iranian traditional medicine, the aerial parts and roots of A. lycioides are used in the treatment of diabetes. Six flavonoids, i.e. quercetin 3-O-rhamnoside (1), luteolin 7-O-rhamnoside (2), isorhamnetin 3-O-rutinoside (3), kaempferol 3-O-rhamnoside (4), apigenin (5), and naringenin (6), have been isolated from the aerial parts of this plant. The structures of these compounds were elucidated by UV, MS, and NMR spectroscopic data analyses. While the antioxidant activity of these compounds was assessed by the 2,2-diphenyl-1-picryl-hydrazyl (DPPH) …
Specific Individuals Of Rainbow Trout (Oncorhynchus Mykiss) Are Able To Show Time-Place Learning, M. Saeed Heydarnejad, G. J. Purser
Specific Individuals Of Rainbow Trout (Oncorhynchus Mykiss) Are Able To Show Time-Place Learning, M. Saeed Heydarnejad, G. J. Purser
Turkish Journal of Biology
Using demand-feeders, time-place learning association of food was investigated in rainbow trout (Oncorhynchus mykiss) in 2 small raceways (TR1 and TR2). In order for the fish to be visually identified, they were tagged individually and their behaviour and distribution were monitored by cameras. Equipping with a demand-feeder, TR1 was assigned to test 2 times/1 place (2T/1P) while 2 demand-feeders were used in TR2 assigned to test 2 times/2 places (2T/2P). After 26 days of restricted feeding (RF) the fish were deprived of food for 3 days. The results of the present study indicate that, at the group level, rainbow trout …
Synthesis And Antifungal Activity Of Some Novel N-(4-Phenyl-3-Aroylthiazol-2(3h)-Ylidene) Substituted Benzamides, Aamer Saeed, Sabah Zaman, Maryam Jamil, Bushra Mirza
Synthesis And Antifungal Activity Of Some Novel N-(4-Phenyl-3-Aroylthiazol-2(3h)-Ylidene) Substituted Benzamides, Aamer Saeed, Sabah Zaman, Maryam Jamil, Bushra Mirza
Turkish Journal of Chemistry
Variously substituted N-(4-phenyl-3-aroylthiazol-2(3H)-ylidene)benzamides (2a-t) were prepared by base-catalyzed cyclization of corresponding 1-aroyl-3-aryl thioureas with acetophenone in the presence of bromine. Some of the synthesized compounds were assayed in vitro for their antifungal activity and were found to exhibit low to moderate activity.
Synthesis And Biological Activity Of Allosteric Modulators Of Gaba_B Receptors. Part 4. Synthesis Of Potentially Fluorescent Acridines And Conformationally Restricted N-(Arylpropyl)-1-Arylethylamines, Jabbar Khalafy, Rolf H. Prager, Ni Made Puspawati
Synthesis And Biological Activity Of Allosteric Modulators Of Gaba_B Receptors. Part 4. Synthesis Of Potentially Fluorescent Acridines And Conformationally Restricted N-(Arylpropyl)-1-Arylethylamines, Jabbar Khalafy, Rolf H. Prager, Ni Made Puspawati
Turkish Journal of Chemistry
A series of 8 new derivatives of fendiline was prepared for evaluation as allosteric modulators of GABA_B receptors: 4 based on acridine and 4 with restricted distance between the 2 aryl moieties.
On Some Algebraic Properties Of Semi-Discrete Hyperbolic Type Equations, İsmagi̇l Habibullin, Asli Pekcan, Natalya Zheltukhina
On Some Algebraic Properties Of Semi-Discrete Hyperbolic Type Equations, İsmagi̇l Habibullin, Asli Pekcan, Natalya Zheltukhina
Turkish Journal of Mathematics
Nonlinear semi-discrete equations of the form t_x(n+1) = f(t(n), t(n+1), t_x(n)) are studied. An adequate algebraic formulation of the Darboux integrability is discussed and an attempt to adopt this notion to the classification of Darboux integrable chains has been undertaken.
Synthesis And Antimicrobial Evaluation Of Novel Di-Triazoles And 4-Arylidene Amino 4,5 Dihydro-1h-[1,2,4] Triazole-5-One Derivatives, Yasemi̇n Ünver, Esra Düğdü, Kemal Sancak, Mustafa Er, Şengül Alpay Karaoğlu
Synthesis And Antimicrobial Evaluation Of Novel Di-Triazoles And 4-Arylidene Amino 4,5 Dihydro-1h-[1,2,4] Triazole-5-One Derivatives, Yasemi̇n Ünver, Esra Düğdü, Kemal Sancak, Mustafa Er, Şengül Alpay Karaoğlu
Turkish Journal of Chemistry
A series of novel di-[3(thiophen-2-yl-methyl)-4,5-dihydro-1H- [1,2,4]triazole-5-one-4yl]n-alkanes (2a-h) were obtained by the reaction of N'-1-ethoxy-2-thiophen-2-yl-ethylydene hydrazino carboxylic acid ethyl ester (1) and diamines. Compound 3 was reacted with aldehydes and 4-(arylidene-amino)-3-thiophen-2-yl-methyl-4,5-dihydro-1H-[1,2,4] triazole-5-ones (4, 5, and 8) with Schiff base character were synthesized. (4-(arylidene-amino)-5-oxo-3-thiophen-2-yl-methyl-4,5- dihydro-1H-[1,2,4]triazole-1-yl)-acetic acid ethyl esters (6, 7, and 9) were obtained by the reaction of 4-(arylidene-amino)-3-thiophen-2-yl- methyl-4,5-dihydro-1H-[1,2,4]triazole-5-ones (4, 5, and 8) and ethyl bromoacetate. The structures of the new compounds were inferred through IR, ^1H/^{13}C NMR, elemental analyses, and mass spectral data. Compound 8i was characterized by IR, ^1H/^{13}C NMR, elemental analyses, mass, and X-ray spectral techniques. Geometry optimization …
Determination Of Iridoid Glycosides From Four Turkish Lamium Species By Hplc-Esi/Ms, Funda Nuray Yalçin, Duygu Kaya, İhsan Çaliş, Tayfun Ersöz, Erhan Palaska
Determination Of Iridoid Glycosides From Four Turkish Lamium Species By Hplc-Esi/Ms, Funda Nuray Yalçin, Duygu Kaya, İhsan Çaliş, Tayfun Ersöz, Erhan Palaska
Turkish Journal of Chemistry
An HPLC-ESI/MS method that enables fast detection and identification of iridoid glycosides is described. Eleven iridoid glycosides known to occur in the genus Lamium-lamalbide, sesamoside, 6-\beta-OH ipolamiide, shanzhiside methyl ester, dehydropenstemoside, barlerin (= 8-O-acetylshanzhiside methyl ester), 6-O-syringyl-8-O- acetylshanzhiside methyl ester, lamerioside, lamiide, eriobioside, and ipolamiide, were identified by means of their retention time and ESI/MS data. This method was successfully applied to the identification of the iridoid composition of the n-butanol extracts of Lamium eriocephalum Bentham subsp. eriocephalum, L. garganicum L. subsp. pulchrum R. Mill, L. garganicum L. subsp. laevigatum Arcangeli, and L. purpureum L. var. purpureum from the Turkish …
Determination Of Antimicrobial And Antioxidant Activities Of Turkish Endemic Salvia Halophila Hedge, Sevi̇l Albayrak, Ahmet Aksoy, Ergi̇n Hamzaoğlu
Determination Of Antimicrobial And Antioxidant Activities Of Turkish Endemic Salvia Halophila Hedge, Sevi̇l Albayrak, Ahmet Aksoy, Ergi̇n Hamzaoğlu
Turkish Journal of Biology
In this study, the antioxidant activity of ethanol extract of Salvia halophila Hedge (Lamiaceae) was evaluated by 2 antioxidant assays, including phosphomolybdenum reduction and free radical scavenging activity. The ethanol extract showed free radical scavenging activity with IC_{50} of 67.73 \mug/mL in 1,1-diphenyl-2-picrylhydrazyl (DPPH) assay. The antioxidant activity of the extract was found to be 84.87 ± 0.7 mg ascorbic acid equivalent (AAE)/g extract in phosphomolybdenum assay. In the addition to the antioxidant activity of the extract, the total phenolic content was measured. Total phenolic content of ethanol extract was found to be 8.21 ± 0.0 mg gallic acid equivalent …
Analysis Of Ki-Ras Exon 2 Gene Mutations In 3-Methylcholanthrene And Butylated Hydroxytoluene-Induced Rat Lung Tissues, Fi̇kri̇ye Polat, Öztürk Özdemi̇r, Şahende Elagöz
Analysis Of Ki-Ras Exon 2 Gene Mutations In 3-Methylcholanthrene And Butylated Hydroxytoluene-Induced Rat Lung Tissues, Fi̇kri̇ye Polat, Öztürk Özdemi̇r, Şahende Elagöz
Turkish Journal of Biology
3-Methylcholanthrene (MCA) is a polycyclic aromatic hydrocarbon and potent carcinogenic agent that is often used in experimental cancer studies. Butylated hydroxytoluene (BHT) has been widely used for many years as an antioxidant to preserve and stabilize the freshness, nutritional value, flavor, and color of foods. The aim of the present study was to investigate the role of the application of MCA and BHT in the development of lung cancer, and to detect any mutation in the Ki-ras gene exon 2. Rats were killed by cervical dislocation 26 weeks after the last BHT injection and lung tissues were surgically removed. Lung …
The Interaction Effects Of Flooding And Kinetin On Growth Criteria, Chlorophyll Content, And 5-Aminolevulinic Acid Dehydratase Activity In Corn Seedlings, Rashid Jamei, Reza Heidari, Jalil Khara, Samad Zare
The Interaction Effects Of Flooding And Kinetin On Growth Criteria, Chlorophyll Content, And 5-Aminolevulinic Acid Dehydratase Activity In Corn Seedlings, Rashid Jamei, Reza Heidari, Jalil Khara, Samad Zare
Turkish Journal of Biology
The interaction effects of kinetin and flooding on growth indexes, chlorophyll content, and the activity of 5-aminolevulinic acid dehydratase (ALA-D; EC 4.2.1.24) in seedlings of corn (Zea mays L. cv. 704) were investigated. Samples were taken 48, 96, 144, and 192 h after the start of treatment. Growth criteria (root length, shoot height, and dry weight) were inhibited more in flooded plants than in control plants. The pattern of growth changes was similar to chlorophyll a and b, as well as ALA-D activity. The exogenous application of kinetin (100 ppm) nullified the resulting decrease in growth and chlorophyll, but only …
Optimization Of Process Parameters For Alkaline Protease Production By Bacillus Licheniformis N-2 And Kinetics Studies In Batch Fermentation, Muhammad Nadeem, Javed Iqbal Qazi, Qurat-Ul-Ain Syed, Shahjahan Baig
Optimization Of Process Parameters For Alkaline Protease Production By Bacillus Licheniformis N-2 And Kinetics Studies In Batch Fermentation, Muhammad Nadeem, Javed Iqbal Qazi, Qurat-Ul-Ain Syed, Shahjahan Baig
Turkish Journal of Biology
Production of alkaline protease from B. licheniformis N-2 was studied in shake flask experiments in growth medium comprised of (g/l): glucose, 10; soybean meal, 10; K_2HPO_4, 5; MgSO_4.7H_2O, 0.5; NaCl, 0.5; CaCl_2.2H_2O, 0.5. Different process parameters, such as fermentation period, initial pH, incubation temperature, agitation speed, and size and age of inoculum, were optimized for the maximum yield of the alkaline protease. Maximum enzyme production (991.04 PU/ml) was obtained after 24 h of incubation at 37 °C in growth medium of pH 10. The optimum inoculum size and age were determined as 2.0% (v/v) and 24 h, respectively. Kinetics of …
Chitinase Production By Serratia Marcescens Gg5, Gursharan Singh, Joginder Ram Sharma, Gurinder Singh Hoondal
Chitinase Production By Serratia Marcescens Gg5, Gursharan Singh, Joginder Ram Sharma, Gurinder Singh Hoondal
Turkish Journal of Biology
Swollen chitin, flake chitin, powder chitin, and mushroom paste were used as substrates for chitinase production by Serratia marcescens GG5 in submerged fermentation. Enzyme production was 0.3 U/ml when the organism was grown in M9 medium supplemented with 0.5% swollen chitin and 0.5% soluble starch. Scanning electron microscopy revealed that Serratia marcescens GG5 digested the chitin flakes by producing chitinase.
In Vivo Anti-Ulcerogenic Activity Of Equisetum Telmateia Ehrh. Extracts Used In Turkish Folk Medicine, İlhan Gürbüz, Erdem Yeşi̇lada
In Vivo Anti-Ulcerogenic Activity Of Equisetum Telmateia Ehrh. Extracts Used In Turkish Folk Medicine, İlhan Gürbüz, Erdem Yeşi̇lada
Turkish Journal of Biology
The aerial part of Equisetum telmateia Ehrh. is used against various conditions including stomachache and peptic ulcer in Turkish folk medicine. In order to prove the claimed anti-ulcerogenic potential of the plant, aqueous and methanol extracts were prepared from aerial parts of E. telmateia and investigated for their anti-ulcerogenic effect on ethanol-induced gastric ulcer model in rats. Pharmacological experiments clearly demonstrated that the oral administration of both methanol and aqueous extracts of Equisetum telmateia Ehrh. plant showed significant stomach protection (77.9% and 100% ulcer inhibition, respectively) against the applied model of ulcerogenesis (P < 0.001). Since both extracts were found significantly active, 80% ethanol was preferred for the extraction of the plant material and this crude methanolic extract was further fractionated by successive solvent extractions with chloroform and H_2O saturated n-BuOH to obtain the chloroform and n-BuOH extracts as well as the remaining aqueous extract. The 80% ethanol extract and the solvent extracts were then submitted to pharmacological assay using the same in vivo experimental ulcer model. All the extracts statistically showed potent anti-ulcerogenic effect on this model (P < 0.001). However, the remaining aqueous extract was found prominent (98.2% ulcer inhibition). Consequently, folkloric utilization of E. telmateia on peptic ulcer has been confirmed in the present study by using ethanol-induced experimental ulcer model in rats.
Investigation Of The Antimutagenic Potentials Of The Methanol Extract Of Origanum Vulgare L. Subsp. Vulgare In The Eastern Anatolia Region Of Turkey, Tüli̇n Özbek, Medi̇ne Güllüce, Fi̇kretti̇n Şahi̇n, Hakan Özkan, Sevgi̇ Sevsay, Özlem Bariş
Investigation Of The Antimutagenic Potentials Of The Methanol Extract Of Origanum Vulgare L. Subsp. Vulgare In The Eastern Anatolia Region Of Turkey, Tüli̇n Özbek, Medi̇ne Güllüce, Fi̇kretti̇n Şahi̇n, Hakan Özkan, Sevgi̇ Sevsay, Özlem Bariş
Turkish Journal of Biology
The aim of this study was to evaluate the antimutagenic activity of the methanol extract of Origanum vulgare L. subsp. vulgare. Antimutagenic activity was estimated by employing the plate incorporation AMES/Salmonella histidine reversion assay. The base pair substitution tester strain Salmonella typhimurium TA1535 and the frame shift mutagen strain S. typhimurium TA1538 were used against direct acting mutagens - sodium azide (NaN_3), 4-nitro-1-quinoline oxide (4NQO) and the S9-dependent mutagen 2-aminofluorene (2AF). The results suggested that in the absence of S9 metabolic activation, all 3 doses (5, 0.5, and 0.05 \mug/plate) of the plant extract tested caused statistically significant (P < 0.05) antimutagenic activity on TA1535 strain, but not on TA1538 strain. However, in the presence of S9 microsomal fraction, the plant extract exerted moderate antimutagenic activity against the 2AF mutagen and reduced mutant colonies in TA1535 and TA1538 strains. As a result, the methanol extract of Origanum vulgare subsp. vulgare showed antimutagenic effects at 5, 0.5, and 0.05 \mug/plate concentrations. These effects may be explained with the antioxidant activity mechanism, changes in membrane lipids, and permeability of ion channels.
Phytoplankton Species Composition And Seasonal Variation At Wadi Al-Arab Dam Lake, Jordan, Ismail M. Saadoun, Erwah Bataineh, Adil Alhandal
Phytoplankton Species Composition And Seasonal Variation At Wadi Al-Arab Dam Lake, Jordan, Ismail M. Saadoun, Erwah Bataineh, Adil Alhandal
Turkish Journal of Biology
The composition of phytoplankton species thriving in Wadi Al-Arab Dam Reservoir, Jordan and their seasonal variation in relation to water ecology were studied between February 2001 and February 2002. A total of 75 species of phytoplankton were identified: Bacillariophyceae (diatoms) contributed with the highest number of taxa (39) followed by Chlorophyceae (23), Cyanophyceae (9), and Dinophyceae (4). Diatoms constituted 52% of the total phytoplankton flora of the reservoir and the most common species were Synedra ulna, Cymbella affinis, and Cyclotella meneghiniana with pennate and centric diatoms being the dominant species in May and October-November, respectively. Although Chlorophytes occurred most of …