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Range Extension And Translocation For Rhodeus Amarus (Bloch, 1782) (Actinopterygii: Cyprinidae) In Northwestern Iran, Hamid Reza Esmaeili, Narges Nazari, Ali Gholamifard, Ghorbanali Gholamhosseini, Azad Teimory, Brian W. Coad
Range Extension And Translocation For Rhodeus Amarus (Bloch, 1782) (Actinopterygii: Cyprinidae) In Northwestern Iran, Hamid Reza Esmaeili, Narges Nazari, Ali Gholamifard, Ghorbanali Gholamhosseini, Azad Teimory, Brian W. Coad
Turkish Journal of Zoology
Based on the new fish collection, the distribution range of the European bitterling, Rhodeus amarus (Bloch, 1782), is extended to a new basin (Urmia) in northwestern Iran.
Microphthalma Europaea Egger (Diptera: Tachinidae), A New Record For Turkey, Mehmet Karagöz, Sadi̇ Aksu, Celaletti̇n Gözüaçik, Kenan Kara
Microphthalma Europaea Egger (Diptera: Tachinidae), A New Record For Turkey, Mehmet Karagöz, Sadi̇ Aksu, Celaletti̇n Gözüaçik, Kenan Kara
Turkish Journal of Zoology
Microphthalma europaea Egger (Diptera: Tachinidae) is recorded as a parasitoid of the last instar larvae of Polyphylla fullo (Linnaeus) (Coleoptera: Scarabaeidae). The adult male and female were used for identification, and this is the first known record of this species in Turkey. This is also a first report of a tachinid obtained from scarabaeid larvae in Turkey.
First Record Of Bilusius Valiko Logvinenko, 1974 (Hemiptera, Cicadomorpha, Cicadellidae) From Turkey, With Redescription Of The Species, Murat Karavi̇n, Ünal Zeybekoğlu, Veysel Kartal
First Record Of Bilusius Valiko Logvinenko, 1974 (Hemiptera, Cicadomorpha, Cicadellidae) From Turkey, With Redescription Of The Species, Murat Karavi̇n, Ünal Zeybekoğlu, Veysel Kartal
Turkish Journal of Zoology
The genus Bilusius Ribaut, 1942 includes 3 species; 2 are from the Pyrenees and 1 is from the Caucasus (Georgia). This study reports both the genus Bilusius and the species Bilusius valiko Logvinenko, 1974, which are recorded here for the first time from Turkey. This species is redescribed and figured by examination of specimens collected from northeastern Turkey.
Investigation Of Extremely Low Frequency (Elf) Hot Spots In The College Of Science And Technology, Covenant University, Ota, Marvel Akinyemi, John Kayode, Mojisola Usikalu
Investigation Of Extremely Low Frequency (Elf) Hot Spots In The College Of Science And Technology, Covenant University, Ota, Marvel Akinyemi, John Kayode, Mojisola Usikalu
Turkish Journal of Physics
The presence of Extremely Low Frequency (ELF) from electronic devices such as personal computers, laboratory equipment and television sets in selected laboratories and offices at the College of Science and Technology Building, Covenant University, Ota, Nigeria was characterized using an ELF Detection Meter. The study revealed that exposure to ELF fields could be controlled to the minimum depending on the awareness of the occupant. As with all electromagnetic fields, the ELF field decays rapidly with distance from source or hot spots. The average observed value of ELF in the offices ranged from 3.5 to 5.0 mG. A significant hot spot …
Existence Theory For Positive Solutions Of P-Laplacian Multi-Point Bvps On Time Scales, You-Hui Su
Existence Theory For Positive Solutions Of P-Laplacian Multi-Point Bvps On Time Scales, You-Hui Su
Turkish Journal of Mathematics
This paper is concerned with the one-dimensional p-Laplacian multi-point boundary value problem on time scales T: (\varphi_p(u^{\Delta}))^{\nabla} + h(t)f(u) = 0, t \in [0,T]_T, subject to multi-point boundary conditions u(0) - B_0(\sum_{i=1}^{m-2}a_i u^{\Delta}(\xi_i)) = 0, u^{\Delta}(T) = 0, or u^{\Delta}(0) = 0, u(T) + B_1(\sum_{i=1}^{m-2}b_iu^{\Delta}(\xi'_i)) = 0, where \varphi_p(u) is p-Laplacian operator, i.e., \varphi_p(u = u ^{p-2}u, p>1, \xi_i,\xi'_i\in [0,T]_T, m \geq 3 and satisfy 0 \leq \xi_1 < \xi_2 < ... < \xi_{m-2} < \rho(T), \sigma(0) < \xi'_1 < \xi'_2 < ... < \xi'_{m-2} \leq T, a_i, b_i\in [0,\infty) (i=1,2,..., m-2). Some new sufficient conditions are obtained for the existence of at least one positive solution by using Krasnosel'skii's fixed-point theorem and new sufficient conditions are obtained for the existence of twin, triple or arbitrary odd positive solutions by using generalized Avery and Henderson fixed-point theorem and Avery-Peterson fixed-point theorem. Our results include and extend some known results. As applications, two examples are given to illustrate the main results and their differences. These results are new even for the special cases of continuous and discrete equations, as well as in the general time scale setting.
Population Variation Of Codling Moth Cydia Pomonella (Lep.; Tortricidae) Based On Molecular Data From Northwestern Iran, Samad Khaghaninia, Seyed Abolgasem Mohammadi, Ali Morad Sarafrazi, Karim Haddad Irani Nejad
Population Variation Of Codling Moth Cydia Pomonella (Lep.; Tortricidae) Based On Molecular Data From Northwestern Iran, Samad Khaghaninia, Seyed Abolgasem Mohammadi, Ali Morad Sarafrazi, Karim Haddad Irani Nejad
Turkish Journal of Zoology
In order to study population structure in the codling moth (Cydia pomonella L.) using RAPD markers, 13 geographical populations from northwestern Iran were collected during 2003 and 2004. Genomic DNA was extracted from 10 overwintering larvae of each population. Out of 60 tested primers, 18 amplified 236 polymorphic bands. The total number of bands in the population varied from 169 to 206 in the Mughan and Zunuz populations, respectively. Within-population genetic diversity, based on Nei's genetic index, ranged from 0.228 to 0.281 for the Shabestar and Zunuz populations, respectively. An analysis of the molecular variance revealed significant differences within and …
Effect Of Ejaculation Frequency On Spermatozoa Survival In Diluted Semen From Pleven Blackhead Rams, Stanimir Yotov, Ivan Fasulkov, Nasko Vassilev
Effect Of Ejaculation Frequency On Spermatozoa Survival In Diluted Semen From Pleven Blackhead Rams, Stanimir Yotov, Ivan Fasulkov, Nasko Vassilev
Turkish Journal of Veterinary & Animal Sciences
The effect of ejaculation frequency on spermatozoa survival in diluted Pleven Blackhead ram semen was investigated. Thirty-two ejaculates were examined. From each ram 4 ejaculates were collected at 10-min intervals in the morning and in the afternoon. Semen parameters, namely, color, density, transparency, volume, concentration, motility, and abnormal sperm, for each ejaculate were determined. The sperm motility was assessed from the moment of dilution up to 60 min at 10-min intervals, then again at 90 min and 120 min. The semen characteristics were determined by means of "Motic Image Plus" equipment and the data were processed statistically. Sperm volume and …
Growth-Invariant Meristic Characters Tools To Reveal Phylogenetic Relationships In Nummulitidae (Foraminifera), Johann Hohenegger
Growth-Invariant Meristic Characters Tools To Reveal Phylogenetic Relationships In Nummulitidae (Foraminifera), Johann Hohenegger
Turkish Journal of Earth Sciences
Morphological characters that are restricted to a few growth-independent characters (such as the embryonic apparatus of nummulitids) or measurements at arbitrarily chosen growth stages (such as the second whorl in planispiral tests) do not adequately explain the phylogenetic relationships of fossil forms. Molecular-genetic investigations enlighten phylogenetic relations, but have two main disadvantages. First, they are restricted to living forms, and second, these relations are based on an extremely small part of the DNA and never on developmental and structural genes that regulate morphology. Morphometric methods based on growth-invariant characters allow modelling the test shape for each growth stage and thus …
Growth Rate Biometric Quantification By X-Ray Microtomography On Larger Benthic Foraminifera: Three-Dimensional Measurements Push Nummulitids Into The Fourth Dimension, Antonino Briguglio, Brian Metscher, Johann Hohenegger
Growth Rate Biometric Quantification By X-Ray Microtomography On Larger Benthic Foraminifera: Three-Dimensional Measurements Push Nummulitids Into The Fourth Dimension, Antonino Briguglio, Brian Metscher, Johann Hohenegger
Turkish Journal of Earth Sciences
This work demonstrates the potential of three-dimensional biometric quantification using microtomography on larger benthic foraminifera. We compare traditional linear and area measures used for calculating three-dimensional characters with actual 3D measurements made from volume images obtained using X-ray microtomography (microCT). Two specimens of recent larger benthic foraminifera, i.e., Palaeonummulites venosus and Operculina ammonoides, were imaged with a high-resolution microCT scanner. This method enables three-dimensional imaging and calculation of measurements like 3D distances, surfaces and volumes. The quantitative high-resolution images enabled the extraction of the lumina from the proloculus to the last complete scanned chamber and of the canal system spreading …
Stability Properties Of Certain Durum Wheat Genotypes For Major Quality Characteristics, Mehmet Ali̇ Saki̇n, Oral Düzdemi̇r, Abdulvahi̇t Sayaslan, Ferhat Yüksel
Stability Properties Of Certain Durum Wheat Genotypes For Major Quality Characteristics, Mehmet Ali̇ Saki̇n, Oral Düzdemi̇r, Abdulvahi̇t Sayaslan, Ferhat Yüksel
Turkish Journal of Agriculture and Forestry
Many ecological regions of Turkey are suitable for the production of durum wheat, and therefore the yield and quality of this wheat should be improved. In this study, stability properties associated with the pasta quality of 25 durum wheat (Triticum durum Desf.) genotypes grown in 3 different locations (Tokat-Kazova, Diyarbakır, and Sivas-Ulaş) for 2 years (2005-2006, 2006-2007) were investigated. Durum wheat genotypes were composed of 12 registered varieties and 13 advanced experimental lines. Field trials were conducted in a randomized complete block design with 3 replications. Protein content, gluten index, sedimentation and specific sedimentation volumes, yellow pigment content, and lipoxygenase …
Estimation Of Single Leaf Chlorophyll Content In Sugar Beet Using Machine Vision, Parviz Ahmadi Moghaddam, Mohammadali Haddad Derafshi, Vine Shirzad
Estimation Of Single Leaf Chlorophyll Content In Sugar Beet Using Machine Vision, Parviz Ahmadi Moghaddam, Mohammadali Haddad Derafshi, Vine Shirzad
Turkish Journal of Agriculture and Forestry
Estimating crop nitrogen status accurately during side-dressing operations is essential for effective management of site-specific nitrogen applications. Variable rate technology (VRT) is one of the major operations in precision agriculture to reduce environmental risks and increase fertilizer use efficiency. In the present study, color image analysis was performed to estimate sugar beet leaf chlorophyll status. The experiment was carried out in a phytotron and nitrogen was applied at 6 levels to the sugar beet grown in pots. Chlorophyll level of the leaves was measured by a SPAD-502 chlorophyll meter. To estimate chlorophyll status, a neural-network model was developed based on …
Soil Texture Fractions And Fractal Dimension Of Particle Size Distribution As Predictors Of Interrill Erodibility, Mohammad Reza Neyshabouri, Abbas Ahmadi, Hassan Rouhipour, Hossein Asadi, Mehdi Irannajad
Soil Texture Fractions And Fractal Dimension Of Particle Size Distribution As Predictors Of Interrill Erodibility, Mohammad Reza Neyshabouri, Abbas Ahmadi, Hassan Rouhipour, Hossein Asadi, Mehdi Irannajad
Turkish Journal of Agriculture and Forestry
Choosing a particular textural fraction as an erodibility predictor is often confusing because various fractions of soil particles have been introduced as erodibility index by many researchers. Recently, advances in fractal theory have introduced a scaling parameter for characterizing soil fragments. The objectives of this study were (i) to test the applicability of fractal dimension of particle size distribution (PSD) for estimation of interrill erodibility and (ii) to study the relationship between interrill erodibility and soil texture components. Samples from 36 soil series with contrasting characters were collected from northwest Iran. The sand fractions were obtained by sieving, while silt …
Utilization Of Boron Compounds As Synergists With Ammonium Polyphosphate For Flame Retardant Wood-Polymer Composites, Ramazan Kurt, Fati̇h Mengeloğlu
Utilization Of Boron Compounds As Synergists With Ammonium Polyphosphate For Flame Retardant Wood-Polymer Composites, Ramazan Kurt, Fati̇h Mengeloğlu
Turkish Journal of Agriculture and Forestry
The investigation consisted of utilizing boron compounds (BCs) as a synergist with ammonium polyphosphate (APP) in manufacturing flame retardant wood-polymer composites (WPCs). Flame retardants (FRs) at various ratios (APP, boric acid (BA), borax (BX), zinc borate and BA/BX mixtures) were used to determine the physical, mechanical, and burning rate properties of WPCs manufactured from wood flour, polypropylene, and maleic anhydride polypropylene. The results showed that the addition of FRs reduced all mechanical properties of WPCs except for impact strength. However, this reduction was lower for samples having BCs in FRs formulation. Similar burning rate results were achieved in WPCs having …
Bioactivities Of Jimsonweed Extract, Datura Stramonium L. (Solanaceae), Against Tribolium Castaneum (Coleoptera: Tenebrionidae), Habib Abbasipour, Mohammad Mahmoudvand, Fahimeh Rastegar, Mohammad Hossein Hosseinpour
Bioactivities Of Jimsonweed Extract, Datura Stramonium L. (Solanaceae), Against Tribolium Castaneum (Coleoptera: Tenebrionidae), Habib Abbasipour, Mohammad Mahmoudvand, Fahimeh Rastegar, Mohammad Hossein Hosseinpour
Turkish Journal of Agriculture and Forestry
In this research, the efficacy of plant extract from Datura stramonium L. (Solanaceae) was tested against the red flour beetle, Tribolium castaneum (Herbst) (Coleoptera: Tenebrionidae), for its toxic and antifeedant activity. The dried and powdered plant was extracted with 150 mL of absolute ethanol (99%, Merck) using a rotary evaporator extractor at 45 °C. Experiments were designed to measure the nutritional indices, such as relative growth rate (RGR), relative consumption rate (RCR), efficiency of conversion of ingested food (ECI), and feeding deterrence index (FDI). Treatments were evaluated by flour disk bioassay in the dark at 27 ± 1 °C and …
Micropropagation Of The Apricot (Prunus Armeniaca L.) Cv. Hacıhaliloğlu By Means Of Single Node Culture, Hakan Yildirim, Ahmet Onay, Engi̇n Ti̇lkat, Zafer Aktürk
Micropropagation Of The Apricot (Prunus Armeniaca L.) Cv. Hacıhaliloğlu By Means Of Single Node Culture, Hakan Yildirim, Ahmet Onay, Engi̇n Ti̇lkat, Zafer Aktürk
Turkish Journal of Agriculture and Forestry
Hacıhaliloğlu is one of the most widely cultivated apricot (Prunus armeniaca L.) cultivars in Turkey. It produces fruit of excellent quality and is consumed both fresh and dried. In this study several factors affecting in vitro culture, rapid proliferation, rooting, and acclimatization of the apricot cultivar Hacıhaliloğlu were examined. During this study significant differences in harvesting dates were observed, with the month of May being noted as the best time to examine the in vitro culture of Hacıhaliloğlu. The effects of the cytokinin 6-benzylaminopurine (BA), kinetin (Kin), and thidiazuron (TDZ) were evaluated individually, and different concentrations of BA were also …
Clonal Propagation And Cryogenic Storage Of Virus-Free Grapevine (Vitis Vinifera L.) Via Meristem Culture, Mohamad Shatnawi, Ghandi Anfoka, Rida Shibli, Mohammed Al-Mazra'awi, Wesam Shahrour, Areej Arebiat
Clonal Propagation And Cryogenic Storage Of Virus-Free Grapevine (Vitis Vinifera L.) Via Meristem Culture, Mohamad Shatnawi, Ghandi Anfoka, Rida Shibli, Mohammed Al-Mazra'awi, Wesam Shahrour, Areej Arebiat
Turkish Journal of Agriculture and Forestry
A protocol for production of virus-free Vitis vinifera using meristem culture was developed. Meristems (0.1-0.2 mm) of V. vinifera infected with grapevine fanleaf virus and grape leafroll associated viruses were excised from 1-year-old growing vines. Shoot tips were cultured on half-strength Murashige and Skoog (MS) medium, supplemented with 0.02 mg L^{-1} of benzylaminopurine (BAP) and 0.01 mg L^{-1} of naphthalene acetic acid (NAA). BAP and kinetin resulted in differences in the number of new shoots per explant, shoot height, and number of new leaves per explant. BAP at 0.8 mg L^{-1} gave the highest in vitro multiplication rate, with 5.25 …
Synthesis And Biological Activity Of 5-Substituted-2-Amino-1,3,4-Oxadiazole Derivatives, Sanjeev Kumar
Synthesis And Biological Activity Of 5-Substituted-2-Amino-1,3,4-Oxadiazole Derivatives, Sanjeev Kumar
Turkish Journal of Chemistry
Electrical energy offers numerous benefits for performing synthesis, including increased reaction rates, enhanced yields, and cleaner chemistries. 5-Substituted-2-amino-1,3,4-oxadiazoles were synthesized directly from the semicarbazone at a platinum electrode under controlled potential electrolysis in an undivided cell assembly in acetonitrile. The compounds were screened for antibacterial and antifungal activity against Staphylococcus aureus, Klebsiella pneumoniae, Pellicularia salmonicolor, and Macrophomina phaseolina.
Antimicrobial Activity And Volatile Constituents Of The Flower, Leaf, And Stem Of Paeonia Daurica Grown In Turkey, Gonca Tosun, Nuran Kahri̇man, Canan Albay, Şengül Alpay Karaoğlu, Nuretti̇n Yayli
Antimicrobial Activity And Volatile Constituents Of The Flower, Leaf, And Stem Of Paeonia Daurica Grown In Turkey, Gonca Tosun, Nuran Kahri̇man, Canan Albay, Şengül Alpay Karaoğlu, Nuretti̇n Yayli
Turkish Journal of Chemistry
The volatile constituents of the essential oils from the flower, leaf, and stem of Paeonia daurica Andrews were analyzed by GC and GC-MS. A total of 74 compounds were identified, constituting over 95.0%, 80.8%, and 98.2% of the oil composition of the flower, leaf, and stem of P. daurica, respectively. Aldehydes were shown to be the main group of constituents of the flower and stem parts, at 39.1% and 79.8%, respectively. However, the major group in the leaf oil was found to be oxygenated monoterpenes (43.5%). Salicylaldehyde (20.7% and 79.5%) was the major component of the flower and stem oils …
Polarographic Determination Of Anticancer Drug Vitamin K_3 With Direct And Indirect Methods/Application To Serum And K_3 Injection Solution, Ümmi̇han Taşkoparan Yilmaz, Güler Somer
Polarographic Determination Of Anticancer Drug Vitamin K_3 With Direct And Indirect Methods/Application To Serum And K_3 Injection Solution, Ümmi̇han Taşkoparan Yilmaz, Güler Somer
Turkish Journal of Chemistry
In this work, direct and indirect methods for determination of vitamin K_3 were developed using differential pulse polarography. The reaction between sulfite and the quinone (Q) form of vitamin K_3 was used for indirect determination, since the sulfite peak at -0.7 V is sharp and very reproducible in 0.1 M HAc NaAc (pH = 5.5). It was found that at pH 4.5-5.5, this reaction was quantitative and very fast when the temperature was 45 °C. For its direct determination, on the other hand, vitamin K_3 was standardized by the indirect method using standard sulfite as the reducing agent. The calibration …
Synthesis And Anti-Helicobacter Pylori Activity Of (4-Nitro-1-Imidazolylmethyl)-1,2,4-Triazoles, 1,3,4-Thiadiazoles, And 1,3,4-Oxadiazoles, Asal Fallah-Tafti, Tahmineh Akbarzadeh, Parastoo Saniee, Farideh Siavoshi, Abbas Shafiee, Alireza Foroumadi
Synthesis And Anti-Helicobacter Pylori Activity Of (4-Nitro-1-Imidazolylmethyl)-1,2,4-Triazoles, 1,3,4-Thiadiazoles, And 1,3,4-Oxadiazoles, Asal Fallah-Tafti, Tahmineh Akbarzadeh, Parastoo Saniee, Farideh Siavoshi, Abbas Shafiee, Alireza Foroumadi
Turkish Journal of Chemistry
A series of [(4-nitro-1H-imidazol-1-yl)methyl]-1,2,4- triazoles and 1,3,4-thiadiazoles were prepared and evaluated for their activity against sensitive and resistant H. pylori strains. Study of the structure-activity relationship of these series of compounds indicated that the type of nitroimidazole moiety and the pendent group on the heteroaryl analog dramatically impact the anti-H. pylori activity. In triazole series, compound 5d, containing a 4-methyl phenyl group on the triazole ring, was the most potent compound tested against both metronidazole-sensitive and -resistant strains at a concentration of 8 \mu g.
E)--2--Acetyl--4--(4--Methoxyphenyldiazenyl) Phenol: X--Ray And Dft--Calculated Structure, Serap Yazici, Çi̇ğdem Albayrak, İsmai̇l Erdem Gümrükçüoğlu, İsmet Şenel, Orhan Büyükgüngör
E)--2--Acetyl--4--(4--Methoxyphenyldiazenyl) Phenol: X--Ray And Dft--Calculated Structure, Serap Yazici, Çi̇ğdem Albayrak, İsmai̇l Erdem Gümrükçüoğlu, İsmet Şenel, Orhan Büyükgüngör
Turkish Journal of Chemistry
The crystal structure of the title compound, (E)-2-acetyl-4-(4-methoxyphenyldiazenyl) phenol, displays a trans configuration of the azo moiety as found for other azo (diazene) derivatives. The aromatic mean planes are nearly coplanar and the dihedral angle between the 2 aromatic rings is 3.04(8)°. The molecules, with strong intramolecular O--H...O hydrogen bonding, are linked by weak van der Waals interactions in the 3-dimensional network. The molecular geometry, determined using X-ray diffraction techniques, was also calculated with the density functional theory (DFT), employing the hybrid exchange-correlation functional B3LYP. Experimental and theoretical IR spectra of the compound were also calculated for comparison. The results …
Microwave Synthesis Of Some New Antimicrobial And Antiproliferative Butenamides And Pyrrolidine-2,5-Diones, Shadia Mahmoud Abdallah, Halima Aly Hefny
Microwave Synthesis Of Some New Antimicrobial And Antiproliferative Butenamides And Pyrrolidine-2,5-Diones, Shadia Mahmoud Abdallah, Halima Aly Hefny
Turkish Journal of Chemistry
Microwave irradiation, comparable to conventional thermal heating, proves to be a convenient method in assisting the synthesis of some butenamides, pyrrolidine-2,5-diones, and their benzenesulfonamido derivatives, which are known to have biological activities and wide medical and industrial applications. Both procedures were used to compare their efficiency in synthesizing butenamides and pyrrolidine-2,5-diones (2-25), which have important and wide applications, from condensation of \alpha,\beta-unsaturated anhydride (1) with the corresponding amines. Some of the products showed biological or cytotoxic (antiproliferative) activity.
Qsar And Docking Studies Of Inhibition Activity Of 5,6-Dihydro 11-Alkylbenzo[\Alpha]Carbazole Derivatives Against Estrogen Receptor, Tuğba Taşkin, Fatma Sevi̇n
Qsar And Docking Studies Of Inhibition Activity Of 5,6-Dihydro 11-Alkylbenzo[\Alpha]Carbazole Derivatives Against Estrogen Receptor, Tuğba Taşkin, Fatma Sevi̇n
Turkish Journal of Chemistry
In the present study, QSAR and docking studies were applied to understand the nature of 5,6-dihydro 11-alkylbenzo[\alpha]carbazole derivatives and to investigate the interactions of homolog series with binding sites on selected a-chains of human estrogen receptors (hER). The best QSAR model was selected, having the correlation coefficient r = 0.924, squared correlation coefficient r^2 = 0.854, standard deviation s = 0.357, and cross-validated squared correlation coefficient Q^2 = 0.755. The QSAR model indicated that the descriptors E-HOMO and heat of formation play an important role in human estrogen receptor inhibitor activities. A docking study was also utilized to visualize the …
In Silico Design Of Novel And Highly Selective Lysine-Specific Histone Demethylase Inhibitors, Ebru Demet Akdoğan, Burak Erman, Kemal Yelekçi̇
In Silico Design Of Novel And Highly Selective Lysine-Specific Histone Demethylase Inhibitors, Ebru Demet Akdoğan, Burak Erman, Kemal Yelekçi̇
Turkish Journal of Chemistry
Histone lysine-specific demethylase (LSD1) is involved in a wide range of epigenetic processes and plays important roles in gene silencing, DNA transcription, DNA replication, DNA repair, and heterochromatin formation. Its active site shows a resemblance to those of 2 homologous enzymes, monamine oxidase A and B (MAO-A and MAO-B.) In the present work, starting from suitable scaffolds and generating thousands of structures from them, 10 potential inhibitors were obtained with structural and physicochemical properties selectively suitable for inhibiting LSD1. iLib Diverse software was used to generate the diverse structures and 3 docking tools, CDOCKER, GOLD, and AutoDock, were used to …
Synthesis And Antimicrobial Activities Of Some Bridged Bis-Benzimidazole Derivatives, Hasan Küçükbay, Ülkü Yilmaz, Ni̇hat Şi̇reci̇, Ayşe Ni̇lay Güvenç
Synthesis And Antimicrobial Activities Of Some Bridged Bis-Benzimidazole Derivatives, Hasan Küçükbay, Ülkü Yilmaz, Ni̇hat Şi̇reci̇, Ayşe Ni̇lay Güvenç
Turkish Journal of Chemistry
Some bis-benzimidazoles derivatives bearing allyl, crotyl, cinammyl, furfuryl, and thenyl groups were synthesized and their in vitro antimicrobial activity determined against gram-positive and gram-negative bacteria, and fungi by disk-diffusion method. The structures of all new compounds were identified by ^1H-NMR, ^{13}C-NMR, and FT-IR spectroscopic techniques and elemental analysis. All the compounds synthesized in this work were examined for their in vitro antimicrobial activities against gram-positive (Staphylococcus aureus and Bacillus megaterium) and gram-negative bacteria (Klebsiella pneumoniae and Escherichia coli), and the yeasts like fungi (Candida globrata and Candida tropicalis). Compared to the reference substances, Cefozine and nystatin, most of the compounds …
Kinetic Spectrophotometric Determination Of Trace Copper(Ii) Ions By Their Catalytic Effect On The Reduction Of Brilliant Cresyl Blue By Ascorbic Acid, Hali̇l İbrahi̇m Ulusoy, Ramazan Gürkan, Mehmet Akçay
Kinetic Spectrophotometric Determination Of Trace Copper(Ii) Ions By Their Catalytic Effect On The Reduction Of Brilliant Cresyl Blue By Ascorbic Acid, Hali̇l İbrahi̇m Ulusoy, Ramazan Gürkan, Mehmet Akçay
Turkish Journal of Chemistry
In the present study, a novel catalytic-kinetic spectrophotometric method was developed for the determination of trace amounts of copper. It is based on the catalytic effect of Cu(II) on the reduction of brilliant cresyl blue (BCB) by ascorbic acid in pH 5.0 acetate buffer medium. The reaction was monitored spectrophotometrically by measuring the decrease in absorbance of BCB at 624 nm. The operating conditions regarding concentration of reagents, pH, time, and temperature were established and optimized in detail. The working curve was linear in the concentration range of 0.1-5.0 \mu g L^{-1}. The maximum percentage error and standard deviation for …
Constituents Of Plantago Major Subsp. Intermedia With Antioxidant And Anticholinesterase Capacities, Ufuk Kolak, Mehmet Boğa, Emi̇ne Akalin Uruşak, Ayhan Ulubelen
Constituents Of Plantago Major Subsp. Intermedia With Antioxidant And Anticholinesterase Capacities, Ufuk Kolak, Mehmet Boğa, Emi̇ne Akalin Uruşak, Ayhan Ulubelen
Turkish Journal of Chemistry
The methanol extract of Plantago major subsp. intermedia (Gilib.) Lange afforded 4 known compounds, namely isomartynoside (1), 10-hydroxymajoroside (2), \beta -sitosterol (3), and ursolic acid (4). Their structures were established by spectroscopic methods. After determination of the total phenolic and flavonoid contents of the methanol extract, the antioxidant potentials of the crude extract and isolated compounds 1-4 were determined by \beta -carotene bleaching, DPPH free radical and ABTS cation radical scavenging, and cupric reducing antioxidant capacity methods. The methanol extract, rich in phenolic contents, indicated the same DPPH free radical scavenging activity (72\% inhibition) as a standard compound, butylated hydroxytoluene, …