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Protective Effects Of Royal Jelly Against Testicular Damage In Streptozotocin-Induced Diabetic Rats, Turan Karaca, Seli̇m Demi̇rtaş, İhsan Karaboğa, Süleyman Ayvaz
Protective Effects Of Royal Jelly Against Testicular Damage In Streptozotocin-Induced Diabetic Rats, Turan Karaca, Seli̇m Demi̇rtaş, İhsan Karaboğa, Süleyman Ayvaz
Turkish Journal of Medical Sciences
To examine the effects of royal jelly (RJ) on testicular damage in streptozotocin (STZ)-induced diabetic rats. Materials and methods: Eighteen adult Wistar albino rats were used, 6 in each of the 3 treatment groups: Group A: control, Group B: STZ-induced diabetes (untreated), Group C: STZ-induced diabetes plus RJ (400 mg/kg daily for 4 weeks). Diabetes was induced by a single intraperitoneal injection of STZ (60 mg/kg). Four weeks after the onset of diabetes, testicular apoptotic cell death was examined using immunohistochemical staining for caspase-3 and Ki67 staining for localization of proliferative cells. Results: Compared with the control, the body and …
An In Vitro And In Vivo Investigation Of The Cytotoxic Effects Of Caffeic Acid (3,4-Dihydroxycinnamic Acid) Phenethyl Ester And Bortezomib In Multiple Myeloma Cells, Ertan Altayli, Özgür Koru, Önder Öngürü, Tayfun İde, Cengi̇zhan Açikel, Meral Sarper, Mualla Pinar Elçi̇, Rahşan Ilikçi Sağkan, Erhan Astarci, Duran Tok, Sali̇m Özenç, Ali̇ Uğur Ural, Feri̇t Avcu
An In Vitro And In Vivo Investigation Of The Cytotoxic Effects Of Caffeic Acid (3,4-Dihydroxycinnamic Acid) Phenethyl Ester And Bortezomib In Multiple Myeloma Cells, Ertan Altayli, Özgür Koru, Önder Öngürü, Tayfun İde, Cengi̇zhan Açikel, Meral Sarper, Mualla Pinar Elçi̇, Rahşan Ilikçi Sağkan, Erhan Astarci, Duran Tok, Sali̇m Özenç, Ali̇ Uğur Ural, Feri̇t Avcu
Turkish Journal of Medical Sciences
In this study, the in vitro and in vivo effectiveness of caffeic acid (3,4-dihydroxycinnamic acid) phenethyl ester (CAPE) in combination with bortezomib, a proteasome inhibitor, was explored in multiple myeloma (MM) cells. Materials and methods: The cytotoxic effects of CAPE and bortezomib were determined by XTT cell proliferation assay. Apoptosis levels were analyzed with annexin V-fluorescein isothiocyanate, nuclear factor kappa beta (NF-\kappaB) was analyzed with electrophoretic mobility-shift assay, and interleukin (IL)-6 levels were analyzed with enzyme-linked immunosorbent assay to evaluate CAPE's mechanism of action. To investigate the in vivo effectiveness of CAPE and bortezomib, an experimental plasmacytoma model was induced …
Comparative Study Of Virulence Factors Among Esβl-Producing And Nonproducing Pseudomonas Aeruginosa Clinical Isolates, Maha Abd El Fattah Khalil, Fatma Ibrahim Sonbol, Abdelfattah Badr, Samh Samir Ali
Comparative Study Of Virulence Factors Among Esβl-Producing And Nonproducing Pseudomonas Aeruginosa Clinical Isolates, Maha Abd El Fattah Khalil, Fatma Ibrahim Sonbol, Abdelfattah Badr, Samh Samir Ali
Turkish Journal of Medical Sciences
\beta-Lactamase production is considered one of the most important resistance mechanisms among virulent Pseudomonas aeruginosa isolates. The aim of this study was to compare the production and antimicrobial resistance patterns of some virulence factors in extended spectrum \beta-lactamase (ES\betaL)-producing and nonproducing P. aeruginosa clinical isolates. Materials and methods: Out of 183 different clinical specimens, 104 Pseudomonas aeruginosa isolates were recovered. The isolates were screened for ESbL production using the double disk diffusion test and phenotypic confirmatory disk diffusion test. All isolates were tested for susceptibility to 25 antimicrobials, as well as for expression of various virulence factors including pigment, hemolysin, …
Serum Vegf Levels In Gastric Cancer Patients: Correlation With Clinicopathological Parameters, Celal İsmai̇l Bi̇lgi̇ç, Mesut Tez
Serum Vegf Levels In Gastric Cancer Patients: Correlation With Clinicopathological Parameters, Celal İsmai̇l Bi̇lgi̇ç, Mesut Tez
Turkish Journal of Medical Sciences
To evaluate the predictive role of the circulating levels of vascular endothelial growth factor (VEGF) in gastric cancer patients. Materials and methods: This study is a case-control study. We measured serum VEGF levels of 30 patients aged between 34 and 83 years with gastric cancer and 30 patients without malignant pathology, operated on for benign pathologies, with ages ranging from 18 to 69. Results: Serum levels of VEGF were correlated with the tumor type classification (signet cell adenocarcinoma) and the presence of adjacent tissue invasion. There was also a positive correlation between serum VEGF and carcinoembryonic antigen levels. Conclusion: In …
Is There Any Impact Of Pet/Ct On Radiotherapy Planning In Rectal Cancer Patients Undergoing Preoperative Imrt?, Di̇clehan Kiliç, Serap Çatli, Şükran Ülger, Lütfi̇ye Özlem Kapucu
Is There Any Impact Of Pet/Ct On Radiotherapy Planning In Rectal Cancer Patients Undergoing Preoperative Imrt?, Di̇clehan Kiliç, Serap Çatli, Şükran Ülger, Lütfi̇ye Özlem Kapucu
Turkish Journal of Medical Sciences
To investigate the effect of positron emission tomography-computed tomography (PET/CT)-based contouring on dosimetric parameters in rectal cancer patients undergoing preoperative intensity-modulated radiation therapy (IMRT). Materials and methods: Preoperative radiation therapy plans with conformal radiotherapy (CRT) or IMRT were created and examined according to the CT- and PET/CT-based contouring of 20 rectal cancer patients, retrospectively. Results: The target volumes delineated with PET/CT were significantly larger than the volumes created by CT (P = 0.043). Dose delivered to 98% of the planning target volume was high in IMRT planning contouring with CT and PET/CT compared with CRT planning, but the difference was …
Investigation Of Tnf-Alpha Gene (G308a) And Gstp1 Gene (Ile105val) Polymorphisms In Turkish Patients With Retinopathy Of Prematurity, Mehmet Türe, Meral Yildiz, Mutlu Karkucak, Emi̇ne Tuna Gülten, Deni̇z Siğirli, Ahmet Tuncer Özmen, Tahsi̇n Yakut
Investigation Of Tnf-Alpha Gene (G308a) And Gstp1 Gene (Ile105val) Polymorphisms In Turkish Patients With Retinopathy Of Prematurity, Mehmet Türe, Meral Yildiz, Mutlu Karkucak, Emi̇ne Tuna Gülten, Deni̇z Siğirli, Ahmet Tuncer Özmen, Tahsi̇n Yakut
Turkish Journal of Medical Sciences
Retinopathy of prematurity (ROP) is one of the most frequent causes of blindness in newborn babies. Currently, its etiology is not fully understood. In this study we aimed to investigate the correlation between a patient group with ROP and a control group in terms of the tumor necrosis factor-alpha (TNF-alpha) (G308A) gene and glutathione-S-transferase P1 (GSTP1) (Ile105Val) gene polymorphism. Materials and methods: Sixty-two patients diagnosed with ROP and 58 control subjects were included in this study. For TNF-alpha (G308A) gene and GSTP1 (Ile105Val) gene polymorphisms, the polymerase chain reaction-restriction fragment length polymorphism method was used. In statistical analysis the significance …
Usage Of Attenuation Coefficients Of Some Tissue-Equivalent Materials, Ayşe Güneş Tanir, Fatma Serap Ketenci̇, Mustafa Hi̇cabi̇ Bölükdemi̇r
Usage Of Attenuation Coefficients Of Some Tissue-Equivalent Materials, Ayşe Güneş Tanir, Fatma Serap Ketenci̇, Mustafa Hi̇cabi̇ Bölükdemi̇r
Turkish Journal of Physics
The total attenuation coefficients of 11 biological targets against photon energies were plotted within the energy range 1-10 MeV. From these plots a possible equation describing the relationship between photon energy and the total attenuation coefficient was derived. The suggested equation is mu/ rho = 0.0696/ surd E. To test the validity of the equation and to compare the results of the total attenuation coefficients of 3 tissue-equivalent materials (bolus, rice grains, and boiled rice) that could not be determined before, they were determined experimentally by using X-rays produced at 6 MV and 18 MV. The results of the experiment …
Studies On Mass Attenuation Coefficient, Mass Energy Absorption Coefficient, And Kerma For Fe Alloys At Photon Energies Of 17.44 To 51.70 Kev, Demet Yilmaz, Yusuf Şahi̇n, Lütfü Demi̇r
Studies On Mass Attenuation Coefficient, Mass Energy Absorption Coefficient, And Kerma For Fe Alloys At Photon Energies Of 17.44 To 51.70 Kev, Demet Yilmaz, Yusuf Şahi̇n, Lütfü Demi̇r
Turkish Journal of Physics
The mass attenuation coefficient (mu_m), the mass energy absorption coefficient (mu_{en}/ rho), and kerma relative to air were determined for some alloys, namely Fe_{0.5}Cr_{0.5}, Fe_{0.7}Cr_{0.3}, Fe_{0.8}Cr_{0.2}, Fe_{0.9}Cr_{0.1}, Fe_{0.2}Ni_{0.8}, Fe_{0.3}Ni_{0.7}, Fe_{0.5}Ni_{0.5}, Fe_{0.6}Ni_{0.4}, Fe_{0.7}Ni_{0.3}, and Fe_{0.8}Ni_{0.2}, at 17.44, 19.63, 22.10, 24.90, 32.06, 36.39, 37.26, 43.74, 44.48, 50.38, and 51.70 photon energies by using an HPGe detector with a resolution of 182 eV at 5.9 keV. The experimental results of mu_m were compared with the theoretical results. The theoretical values of mu_{en}/ rho were compared with the semiempirical values. It was observed that kerma values relative to air values were different in Fe-Ce …
Symmetry And The Order Of Events In Time: The Thermodynamics Of Blackbodies Composed Of Positive Or Negative Masssymmetry And The Order Of Events In Time: The Thermodynamics Of Blackbodies Composed Of Positive Or Negative Mass, Randy Wayne
Turkish Journal of Physics
I have previously proposed a discrete symmetry called CPM (charge-parity-mass) symmetry that defines matter as having positive mass and antimatter as having negative mass-both being involved in processes that proceed forward in time. I have generalized the second law of thermodynamics to describe and predict the order of events in time that take place in reversible thermodynamic systems composed of positive or negative mass. Here I extend the CPM symmetry to irreversible thermo-optical radiation systems characterized by the Stefan-Boltzmann law, Planck's blackbody radiation law, and Einstein's law of specific heat. The laws of radiation analyzed in terms of CPM symmetry …
Soil Bacteria Conferred A Positive Relationship And Improved Salt Stress Tolerance In Transgenic Pea (Pisum Sativum L.) Harboring Na+/H+ Antiporter, Zahid Ali, Nasr Ullah, Saadia Naseem, Muhammad Inam Ul Haq, Hans Joerg Jacobsen
Soil Bacteria Conferred A Positive Relationship And Improved Salt Stress Tolerance In Transgenic Pea (Pisum Sativum L.) Harboring Na+/H+ Antiporter, Zahid Ali, Nasr Ullah, Saadia Naseem, Muhammad Inam Ul Haq, Hans Joerg Jacobsen
Turkish Journal of Botany
Among grain legumes, peas (Pisum sativum L.) are highly sensitive to salt stress. Acclimatization of plants to such conditions is mandatory. We provide improved salt stress tolerance response of transgenic pea plants overexpressing the Na+/H+ gene from Arabidopsis thaliana and a positive association with salt-tolerant plant growth-promoting rhizobacteria (PGPR). In addition to salt stress tolerance and phosphate solubilization, the selected rhizobacterial isolates were identified for indole acetic acid and proline production ability. Seed germination percentage in transgenic pea plants was significantly higher under NaCl challenge. The wild-type (WT) pea plants inoculated with known numbers of viable cells of salt-tolerant PGPR …
Kinetics And Performance Studies Of A Switchable Solvent Tmg (1,1,3,3-Tetramethylguanidine)/1-Propanol/Carbon Dioxide System, Özge Yüksel, Mustafa Çağdaş Öztürk, Ayça Şeker, Erdoğan Alper
Kinetics And Performance Studies Of A Switchable Solvent Tmg (1,1,3,3-Tetramethylguanidine)/1-Propanol/Carbon Dioxide System, Özge Yüksel, Mustafa Çağdaş Öztürk, Ayça Şeker, Erdoğan Alper
Turkish Journal of Chemistry
The rate constants and the activation energies of the reaction between carbon dioxide and 1,1,3,3-tetramethylguanidine (TMG) in 1-propanol solution were measured by a stopped-flow technique at a temperature range of 288--308 K and at a TMG concentration range of 2.5--10.0 wt %. Based on the pseudo-first-order reaction for CO_2, the reaction was modeled by a termolecular reaction mechanism, which resulted in a rate constant of 199.30 m^3 kmol^{-1} s^{-1} at 298 K. The activation energies were 5.19 kJ/mol and 5.26 kJ/mol at 2.5 and 5.0 wt % TMG, respectively. In addition, carbon dioxide absorption capacity was investigated using a gas--liquid …
Dual Effect Of Coumarin Benzimidazolium Ionic Salt Covalently Bonded On A Silica Network, Ahmet Gültek, Davut Aksüt, Turgay Seçki̇n, Emre Bi̇rhanli, Mert Olgun Karataş, Bülent Alici
Dual Effect Of Coumarin Benzimidazolium Ionic Salt Covalently Bonded On A Silica Network, Ahmet Gültek, Davut Aksüt, Turgay Seçki̇n, Emre Bi̇rhanli, Mert Olgun Karataş, Bülent Alici
Turkish Journal of Chemistry
Synthesis of the ionic liquid 1-allyl-3-(4-methyl-7,8-dihydroxy-2H-chromen-2-one) benzimidazolium chloride followed by the conversion of ammonium salts on the imidazole ring hooked to the coumarin group was modified by postmodification of the silica matrix where 3-chloropropyltrimethoxysilane was used as not only a surface modification agent, but also as an ATRP halogen source. The synergetic effect of charged ammonium groups as well as hydroxyl groups present on the coumarin was investigated in terms of ATRP polymerization. The results confirmed that brush polymers show outstanding antibacterial effects against Escherichia coli, Staphylococcus aureus, and Pseudomonas aeruginosa.
A Comparative Analysis Of Membrane Intactness And Genome Integrity In Pea,Barley, And Wheat In Response To Uvc Irradiation, Mariyana Georgieva, Ivelina Nikolova, Georgi Bonchev, Zornitsa Katerova, Dessislava Todorova
A Comparative Analysis Of Membrane Intactness And Genome Integrity In Pea,Barley, And Wheat In Response To Uvc Irradiation, Mariyana Georgieva, Ivelina Nikolova, Georgi Bonchev, Zornitsa Katerova, Dessislava Todorova
Turkish Journal of Botany
The maintenance of plant genome integrity plays a critical function in the processes of DNA replication, transcription, and repair. Short-wave UV radiation (UVC) is among the most harmful agents known to affect genome stability and to induce DNA damage, including double-strand breaks (DSBs). Most previous studies in plants addressed the effects of UVC radiation at the physiological level; however, little research effort has been put into genome sensitivity across different plant species. Here, we made use of the trypan blue exclusion test and neutral comet assay to assess nuclear membrane and genome integrity in response to UVC radiation in monocot …
Cdna Cloning, Molecular Characterization, And Expression Analyses Of Two Novel Porcine Arrdc Genes-Arrdc1 And Arrdc, Hailong Huo, Pei Wang, Shuyan Wang, Yongwang Miao, Hongjiang Wei, Yongyun Zhang, Qiaoling Zhang, Fuquan Li, Lixian Liu, Rui Wang, Weizhen Li, Yue Zhao, Jinlong Huo, Heng Xiao
Cdna Cloning, Molecular Characterization, And Expression Analyses Of Two Novel Porcine Arrdc Genes-Arrdc1 And Arrdc, Hailong Huo, Pei Wang, Shuyan Wang, Yongwang Miao, Hongjiang Wei, Yongyun Zhang, Qiaoling Zhang, Fuquan Li, Lixian Liu, Rui Wang, Weizhen Li, Yue Zhao, Jinlong Huo, Heng Xiao
Turkish Journal of Biology
Arrestin-domain-containing proteins belong to the arrestin family, embers of which are important for regulating signal transduction within cells. In this study, two ARRDC genes (ARRDC1 and ARRDC5) of Diannan small-ear pigs were amplified by reverse transcription polymerase chain reaction and cloned for the first time (accession nos.: KF589202 and KF589203). The full-length coding sequence of ARRDC1 was 1284 nucleotides in length (molecular weight, 45.6 kDa; pI, 7.61) and encoded 427 amino acids. The ARRDC5CDS was 1014 nucleotides in length (molecular weight, 37.5 kDa; pI, 7.08) and encoded 337 amino acids. Sequence homology analysis revealed that the amino acid sequences of …
Effects Of Gradual Soil Drought Stress On The Growth, Biomass Partitioning, And Chlorophyll Fluorescence Of Prunus Mongolica Seedlings, Youyan Guo, Hongyuan Yu, Dongsheng Kong, Fang Yan, Donghua Liu, Yajuan Zhang
Effects Of Gradual Soil Drought Stress On The Growth, Biomass Partitioning, And Chlorophyll Fluorescence Of Prunus Mongolica Seedlings, Youyan Guo, Hongyuan Yu, Dongsheng Kong, Fang Yan, Donghua Liu, Yajuan Zhang
Turkish Journal of Biology
The present studyaimed to determine the effects of gradual drought stress on Prunus mongolica seedlings. The growth and chlorophyll fluorescence of the seedlings were investigated under drought and control conditions. The short-term (21 day) decline in soil water content from 30.46% to 15.55% did not significantly influence the growth of P. mongolica seedlings but increased the height, basal diameter, crown, leaf number, stem mass, leaf mass, and root mass of the seedlings. The growth of the drought group reached the maximum, but remained lower than that of the control group, within 21 days. Compared with the control group, the drought …
Ghrelin Effects On Midgut Tissue Antioxidative Defense And Glutathione S-Transferase Activity In Lymantria Dispar (Lepidoptera), Vesna Peric Mataruga, Milena Vlahovic, Marija Mrdakovic, Dragana Matic, Anja Gavrilovic, Aleksandra Mrkonja, Larisa Ilijin
Ghrelin Effects On Midgut Tissue Antioxidative Defense And Glutathione S-Transferase Activity In Lymantria Dispar (Lepidoptera), Vesna Peric Mataruga, Milena Vlahovic, Marija Mrdakovic, Dragana Matic, Anja Gavrilovic, Aleksandra Mrkonja, Larisa Ilijin
Turkish Journal of Biology
The aim of the study was to examine changes in Cu?Zn superoxide dismutase (SOD), catalase (CAT), their gel electrophoresis profiles, glutathione reductase (GR) activity, amount of glutathione (GSH), and the activity of glutathione S-transferase (GST) - phase II biotransformation enzyme in the midgut tissue of gypsy moth (Lymantria dispar L. (Lepidoptera: Lymantriidae)) larvae after ghrelin treatment. Four subpicomolar injections of ghrelin (0.3 pmol) or physiological saline (control) were applied every 24 h. The SOD, CAT, GR, GST activity, and amount of GSH were higher in the ghrelin-treated group than in the control. Electrophoresis gel bands of SOD and CAT had …
Genetic Integrity Assessment Of Cryopreserved Tomato (Lycopersicon Esculentum Mill.) Genotypes, Ana Coste, Dana Suteu, Ioan Bacila, Constantin Deliu, Sergiu Valimareanu, Adela Halmagyi
Genetic Integrity Assessment Of Cryopreserved Tomato (Lycopersicon Esculentum Mill.) Genotypes, Ana Coste, Dana Suteu, Ioan Bacila, Constantin Deliu, Sergiu Valimareanu, Adela Halmagyi
Turkish Journal of Biology
Shoot tips of five tomato (Lycopersicon esculentum Mill.) genotypes were successfully cryopreserved by droplet vitrification. Recovered plants were studied for genetic stability by two different assays: amplified fragment length polymorphism (AFLP) using 4 primer combinations and sequencing of lycopene $\beta$-cyclase gene (LCY-B) from leaves. The highest shoot regeneration after cryopreservation was 70% (Pontica) following 24 h osmoprotection in 0.5 M sucrose and 30 min dehydration in plant vitrification solution 2 (PVS2). The data inferred from AFLP showed no genetic dissimilarities between in vitro regenerants derived from cryopreserved tissues compared with the noncryopreserved controls. Although a single nucleotide polymorphism, a G→T …
Mitochondrial Dna-Related Disorders: Emphasis On Mechanisms And Heterogeneity, Umut Cagin, Jose Antonio Enriquez
Mitochondrial Dna-Related Disorders: Emphasis On Mechanisms And Heterogeneity, Umut Cagin, Jose Antonio Enriquez
Turkish Journal of Biology
Mitochondrial diseases are a heterogeneous group of disorders that are currently the focus of intense research. The many cell functions performed by mitochondria include ATP production, calcium homeostasis, and apoptosis. One of the unique properties of mitochondria is the existence of a separate mitochondrial genome (mitochondrial DNA, mtDNA) found in varying copy numbers and containing 37 genes, 13 of them encoding proteins. All 13 mitochondrially encoded proteins form part of oxidative phosphorylation complexes through combination with approximately 100 nuclear DNA-encoded proteins. Coregulation of nDNA and mtDNA is therefore essential for mitochondrial function, and this coregulation contributes to the heterogeneity and …
Expression Profiles Of Genes Related To Melatonin And Oxidative Stress In Human Renal Proximal Tubule Cells Treated With Antibiotic Amphotericin B And Its Modified Forms, Joanna Gola, Aleksandra Skubis, Bartosz Sikora, Celina Kruszniewska-Rajs, Jolanta Adamska, Urszula Mazurek, Barbara Strzalka-Mrozik, Grzegorz Czernel, Mariusz Gagos
Expression Profiles Of Genes Related To Melatonin And Oxidative Stress In Human Renal Proximal Tubule Cells Treated With Antibiotic Amphotericin B And Its Modified Forms, Joanna Gola, Aleksandra Skubis, Bartosz Sikora, Celina Kruszniewska-Rajs, Jolanta Adamska, Urszula Mazurek, Barbara Strzalka-Mrozik, Grzegorz Czernel, Mariusz Gagos
Turkish Journal of Biology
Melatonin protects cells from oxidative stress caused by antibiotics. Through the generation of reactive oxygen species (ROS), amphotericin B (AmB) causes oxidative injuries of the kidneys and liver. Generation of oxidized forms of AmB (AmB-ox) in a patient's circulation may also generate ROS, causing side effects. Studies aimed at elimination of toxic properties of AmB are focused on forming complexes of AmB with copper(II) ions (AmB-Cu2+). However, the influence of such modified forms on renal cells and their transcriptome has not been studied so far. Therefore, the aim of this study was to answer the question of whether AmB-Cu2+ complexes …
The Effects Of Midazolam And Etomidate On The Antioxidant System In The Rat Liver, Di̇lek Bayram, Meral Öncü, Efkan Uz, Haci Ramazan Yilmaz, Ayşe Yi̇ği̇t, Ahmet Koçak
The Effects Of Midazolam And Etomidate On The Antioxidant System In The Rat Liver, Di̇lek Bayram, Meral Öncü, Efkan Uz, Haci Ramazan Yilmaz, Ayşe Yi̇ği̇t, Ahmet Koçak
Turkish Journal of Biology
This study was conducted to investigate the histopathological and biochemical effects of midazolam and etomidate, which are intravenous anesthetics used in surgical operations, on rat liver. There were 3 study groups each consisting of 9 animals: the control, midazolam, and etomidate groups. Midazolam and etomidate were administered 10 times with 1-day intervals. At the end of the study, tissues were taken for histological examination and biochemical analysis. We determined superoxide dismutase (SOD), catalase (CAT), and malondialdehyde (MDA) levels in the liver. There was a slight increase in MDA level in the midazolam-exposed group when compared with the controls, and this …
Melatonin Induces Antiproliferative Activity Through Modulation Of Apoptoticpathway In H-Ras Oncogene Transformed 5rp7 Cells, Ayşe Kaplan, Gülşen Akalin Çi̇ftçi̇, Hati̇ce Mehtap Kutlu
Melatonin Induces Antiproliferative Activity Through Modulation Of Apoptoticpathway In H-Ras Oncogene Transformed 5rp7 Cells, Ayşe Kaplan, Gülşen Akalin Çi̇ftçi̇, Hati̇ce Mehtap Kutlu
Turkish Journal of Biology
In the present study, cytotoxic and apoptotic effects of melatonin were investigated on H-ras oncogene transformed rat embryo fibroblast 5RP7 cells. Melatonin inhibited cell growth and induced apoptosis in 5RP7 cells. We showed inhibition of cell proliferation that was time- and dose-dependent in 5RP7 cells for 24 and 48 h. Melatonin was not toxic in NIH/3T3 primary mouse embryonic fibroblast cells at low doses for 24 and 48 h. The IC50 (380 μM) value of melatonin for 48 h was chosen for advanced assays. The percentages of early/late apoptotic cells to which melatonin (IC50: 380 μM) was administered were increased …
The Effects Of Topical Melatonin On Oxidative Stress, Apoptosis Signals,And P53 Protein Expression During Cutaneous Wound Healing, Azi̇ze Şener, Özge Çevi̇k, Özge Doğan, Nazli Gül Altindi̇ş, Hali̇l Aksoy, Betül Okuyan
The Effects Of Topical Melatonin On Oxidative Stress, Apoptosis Signals,And P53 Protein Expression During Cutaneous Wound Healing, Azi̇ze Şener, Özge Çevi̇k, Özge Doğan, Nazli Gül Altindi̇ş, Hali̇l Aksoy, Betül Okuyan
Turkish Journal of Biology
Elimination of reactive oxygen species (ROS) can be an important strategy to improve healing of wounds. ROS have an effect on proliferation and cell survival signaling, which results in alteration of apoptotic pathways in cells. Melatonin has antioxidant properties on skin wounds. In our study, we investigated the effects of topical melatonin (3%, w/w) on apoptosis and p53 protein expression together with parameters of oxidative stress in a cutaneous excision wound model. Bcl-2 protein levels in wound tissue at the end of days 3, 7, and 14 were significantly increased, while caspase-3 activity and p53 protein expression in wound tissue …
Growth, Yield, And Calcium And Boron Uptake Of Tomato(Lycopersicon Esculentum L.) And Cucumber (Cucumis Sativus L.) Asaffected By Calcium And Boron Humate Application In Greenhouse Conditions, Melek Eki̇nci̇, Aslihan Esri̇ngü, Ati̇lla Dursun, Ertan Yildirim, Meti̇n Turan, Mehmet Rüştü Karaman, Tuba Arjumend
Growth, Yield, And Calcium And Boron Uptake Of Tomato(Lycopersicon Esculentum L.) And Cucumber (Cucumis Sativus L.) Asaffected By Calcium And Boron Humate Application In Greenhouse Conditions, Melek Eki̇nci̇, Aslihan Esri̇ngü, Ati̇lla Dursun, Ertan Yildirim, Meti̇n Turan, Mehmet Rüştü Karaman, Tuba Arjumend
Turkish Journal of Agriculture and Forestry
The objective of this study was to examine the effect of calcium humate, boron humate, and humic acid solutions on growth, yield, quality, and calcium and boron uptake of tomato (Lycopersicon esculentum L.) and cucumber (Cucumis sativus L.), as well as changes in soil nutrient status after crop harvest. Four different concentrations (500, 1000, 3000, and 5000 mg kg-1) of calcium humate (12% CaO, 15% humic and fulvic acid), boron humate (10% BOH4, 15% humic and fulvic acid), and humic acid (15% humic and fulvic acid) were used in this research. The results revealed that Ca humate, B humate, and …
Physical And Chemical Properties Of Recently Deposited Sediments In The Reservoir Of The Borçka Dam In Artvin, Turkey, Bülent Turgut, Mehmet Özalp, Bahti̇yar Köse
Physical And Chemical Properties Of Recently Deposited Sediments In The Reservoir Of The Borçka Dam In Artvin, Turkey, Bülent Turgut, Mehmet Özalp, Bahti̇yar Köse
Turkish Journal of Agriculture and Forestry
Large dams produce important changes in flow regime and sediment deposition and distribution in rivers. When inundation starts with the building of dams, water surface area increases, flow rate decreases, and sediment carried by the river is deposited in the reservoir. However, there is a lack of research on the physical and chemical properties of recently deposited sediment in reservoirs of large dams. We aimed to fill this gap in the literature by providing valuable data on the initial formation of sediment deposition areas in reservoirs. Therefore, the aim of this study conducted within the Borçka Dam reservoir was to …
The Modified Qualities Of Basil Plants By Selenium And/Or Ascorbic Acid, Zahra Oraghi Ardebili, Narges Oraghi Ardebili, Sara Jalili, Somayeh Safiallah
The Modified Qualities Of Basil Plants By Selenium And/Or Ascorbic Acid, Zahra Oraghi Ardebili, Narges Oraghi Ardebili, Sara Jalili, Somayeh Safiallah
Turkish Journal of Botany
The current research aimed to evaluate the possible impacts of foliar supplementations of selenium (Se) and/or ascorbic acid (AsA) on basil. Seedlings were foliarly treated with 4 concentrations of Se (0, 30, 60, and 120 mg L-1) and/or 2 levels of AsA (0 and 200 mg L-1), 2 times with 2-week intervals. In contrast to Se30, chla contents were significantly decreased by Se120 compared with the control. Se applications had a reducing effect on chlb contents. Se and/or AsA treated plants exhibited higher contents of carotenoid. The antioxidative system was affected by the applied treatments as it was indicated by …
Temperature Sensitivity Of Photosystem Ii In Isolated Thylakoid Membranes From Fluridone-Treated Pea Leaves, Kolyo Dankov, Georgi Rashkov, Amarendra Misra, Emilia L. Apostolova
Temperature Sensitivity Of Photosystem Ii In Isolated Thylakoid Membranes From Fluridone-Treated Pea Leaves, Kolyo Dankov, Georgi Rashkov, Amarendra Misra, Emilia L. Apostolova
Turkish Journal of Botany
High temperature-induced changes in the photosystem II (PSII) activity of thylakoid membranes isolated from pea (Pisum sativum L. 'Ran') plants treated with low (10-8 M) and high (10-7 M) concentrations of fluridone were investigated. Pulse amplitude modulated (PAM) chlorophyll fluorescence and photosynthetic oxygen evolution (measured by polarographic oxygen rate electrode) were used to estimate the effect of high temperature on the functional activity of PSII. Higher temperature treatments lead to stronger inhibition of the flash oxygen evolution than the primary photochemistry of PSII (Fv/Fm). The inhibitory effect of higher temperature on the PSII? centers is stronger than on the PSIIß …
Cytogenetic Studies On Some Scorzonera L. S.L. (Asteraceae) Taxa From Turkey, Fahi̇m Altinordu, Esra Marti̇n, Serdar Makbul, Kami̇l Çoşkunçelebi̇, Mutlu Gültepe
Cytogenetic Studies On Some Scorzonera L. S.L. (Asteraceae) Taxa From Turkey, Fahi̇m Altinordu, Esra Marti̇n, Serdar Makbul, Kami̇l Çoşkunçelebi̇, Mutlu Gültepe
Turkish Journal of Botany
In the present study, chromosome morphology of 32 Scorzonera L. Taxa, including 19 species endemic to Turkey, was analyzed. The plant materials were collected from different natural populations of Turkey between 2005 and 2011. The classification of chromosomes, the length of the long and short arm, haploid chromosome length, arm ratio, and relative chromosomal length were measured by software image analyses. The basic chromosome numbers were determined as x = 6 and x = 7. Two types of ploidy levels were observed as diploidy and tetraploidy. Karyotype asymmetry indices, TF%, As K%, Syi, Rec, A, A1, and A2 were also …
Micromorphological Characters On Nutlet And Leaf Indumentum Of Teucrium Sect. Teucrium (Lamiaceae) In Turkey, Gülay Ecevi̇t Genç, Taner Özcan, Tuncay Di̇rmenci̇
Micromorphological Characters On Nutlet And Leaf Indumentum Of Teucrium Sect. Teucrium (Lamiaceae) In Turkey, Gülay Ecevi̇t Genç, Taner Özcan, Tuncay Di̇rmenci̇
Turkish Journal of Botany
Leaf indumentum and nutlet surface micromorphology of 13 taxa belonging to the Teucrium sect. Teucrium was studied with a scanning electron microscope. We observed 5 trichome types on the nutlets and 8 trichome types on the leaves. Branched trichomes were not found on the nutlets. Nutlet shapes of the taxa were elliptic, obovate, oblong, or rotund, and their surfaces were generally alveolate with different ornamentations. Some nutlets had longitudinal ridges. The indumentum varied among unrelated species and showed some significant similarities within related species. In Flora of Turkey sect. Teucrium was divided into 2 groups according to leaf fragmentation and …
Syntaxonomic Analysis Of The Preforest And Forest Vegetation In The Thermo- And Eumediterranean Zone Around Antalya Gulf, Turkey, Lati̇f Kurt, Ali̇ Osman Ketenoğlu, Yildirim Akman, Ebru Özdeni̇z, Fatoş Şekerci̇ler, Ayşenur Bölükbaşi, Beste Gi̇zem Özbey
Syntaxonomic Analysis Of The Preforest And Forest Vegetation In The Thermo- And Eumediterranean Zone Around Antalya Gulf, Turkey, Lati̇f Kurt, Ali̇ Osman Ketenoğlu, Yildirim Akman, Ebru Özdeni̇z, Fatoş Şekerci̇ler, Ayşenur Bölükbaşi, Beste Gi̇zem Özbey
Turkish Journal of Botany
The aim of the current study was to reveal the syntaxonomical structure of Pinus brutia Ten. Forests and the preforest communities in the vicinity of Antalya Gulf. Of the preforest communities, Dorsytaecho hastatae-Oleutum oleastri ass. Nova is individualized as a paraclimax association. Although little is known about the syntaxonomy of the communities of cliff, rupicolous, and mural communities in the thermomediterranean zone, these are connected with the classes Asplenietea trichomanis (Br.-Bl. İn Meier and Br.-Bl. 1934) Oberd. 1977 and Onosmetalia frutescentis Quézel 1964. In the west of the gulf, Phlomido bourgaei-Pinetum brutiae Akman et al. 1998 and its three subassociations …
Expanding The Understanding Of A Forest Ectomycorrhizal Community By Combining Root Tips And Fruiting Bodies: A Case Study Of Tuber Magnatum Stands, Giorgio Lalli, Marco Leonardi, Marilena Oddis, Giovanni Pacioni, Elena Salerni, Mirco Iotti, Alessandra Zambonelli
Expanding The Understanding Of A Forest Ectomycorrhizal Community By Combining Root Tips And Fruiting Bodies: A Case Study Of Tuber Magnatum Stands, Giorgio Lalli, Marco Leonardi, Marilena Oddis, Giovanni Pacioni, Elena Salerni, Mirco Iotti, Alessandra Zambonelli
Turkish Journal of Botany
A survey of both ectomycorrhizal (ECM) root tips and fruiting bodies of ECM fungi was carried out during a four-year period (2009-2012) in two similar forest stands in central Italy, previously investigated in detail being habitats of the Italian white truffle Tuber magnatum Pico. This research is one of the few conducted in mixed forest stands and, for the first time, it took into account the cryptic fungi (corticiaceous, hypogeous, and sclerotia). This survey led to an exhaustive description of the ECM community by integrating all the 197 taxa recorded (147 species as fruiting bodies, 65 as ectomycorrhizas, and 15 …