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Synthesis Of Novel Sn38-Aspirin Prodrugs For The Treatment Of Hepatocellular Carcinoma, Zhimin Chen, Yi Luo, Aiping Fang, Chen Fan, Chenjuan Zeng Jan 2018

Synthesis Of Novel Sn38-Aspirin Prodrugs For The Treatment Of Hepatocellular Carcinoma, Zhimin Chen, Yi Luo, Aiping Fang, Chen Fan, Chenjuan Zeng

Turkish Journal of Chemistry

Hepatocellular carcinoma (HCC) is the most common primary liver malignancy and is a leading cause of cancer-related death worldwide. However, there is no effective chemotherapeutic treatment for HCC and its prognosis remains poor. Consequently, it is urgent to find an efficient antitumor agent to treat HCC. In this study, 7-ethyl-10-hydroxycamptothecin (SN38), the bioactive metabolite of the anticancer drug irinotecan (CPT-11), which is 100-1000 times more potent than CPT-11, was coupled with aspirin to give 4 prodrugs. Their structures were characterized by $^{1}$H~NMR and elemental analysis. The in vitro anticancer activities of these compounds on two human hepatocellular carcinoma cell lines …


A Novel One-Pot And Rapid Synthesis Of Polyfunctionalized Benzo[A]Pyrimido[5',4':5,6] Pyrido[2,3-C]Phenazine Derivatives Under Microwave Irradiation, Mahdieh Tabibian, Razieh Mohebat, Masoumeh Tabatabaee Jan 2018

A Novel One-Pot And Rapid Synthesis Of Polyfunctionalized Benzo[A]Pyrimido[5',4':5,6] Pyrido[2,3-C]Phenazine Derivatives Under Microwave Irradiation, Mahdieh Tabibian, Razieh Mohebat, Masoumeh Tabatabaee

Turkish Journal of Chemistry

A one-pot, environmentally friendly, and efficient protocol for the synthesis of novel polyfunctionalized benzo[$a$]pyrimido[5',4':5,6]pyrido[2,3-$c$]phenazine derivatives has been reported by a one-pot, four-component sequential reaction between 2-hydroxynaphthalene-1,4-dione, benzene-1,2-diamines, benzaldehydes, and 6-amino-1,3-dimethyluracil in the presence of $p$-TSA as a nontoxic, inexpensive, ecofriendly, and efficacious solid acid catalyst. Two C-C bonds, two C=N bonds, and one C-N bond, as well as two new rings, were formed in this reaction. Through this procedure, compounds with substantial biological and pharmaceutical properties are generated in a single operation. Factors such as high yields, less reaction time, operational simplicity, and lack of any dangerous reagents/solvents have made …


A Rapid And Sensitive Spectrofluorometric Method For The Determination Of Au(Iii) Based On Fluorescence Quenching Of A 1,3,5-Triphenyl-2-Pyrazoline, Aysel Başoğlu, Ümmühan Ocak, Seda Fandakli, Nuretti̇n Yayli Jan 2018

A Rapid And Sensitive Spectrofluorometric Method For The Determination Of Au(Iii) Based On Fluorescence Quenching Of A 1,3,5-Triphenyl-2-Pyrazoline, Aysel Başoğlu, Ümmühan Ocak, Seda Fandakli, Nuretti̇n Yayli

Turkish Journal of Chemistry

A simple, rapid, sensitive, and low-cost spectrofluorometric method was developed for the determination of Au(III) using 5-(2,3-dimethoxyphenyl)-3-(4-methoxyphenyl)-1-phenyl-4,5-dihydro-1H-pyrazole (L) in ethanol/water. The method is based on the change in the fluorescence intensity at 464 nm after excitation at 355 nm as a result of the reaction between the ligand and Au(III). The fluorescent emission of ligand at 464 nm decreased with the increasing of Au(III) concentration. The ligand concentration, pH effect, response time, and effect of foreign ions were determined. From the results of fluorescence titration experiments, it was found that the ligand (1 $\times $ 10$^{-7}$ M) was selective and …


Development Of A Nanoscale-Based Optical Chemical Sensor For The Detection Of No Radical, Özlem Öter, Aki̇f Ci̇han Aydin, Merve Zeyrek Ongun, Erdal Çeli̇k Jan 2018

Development Of A Nanoscale-Based Optical Chemical Sensor For The Detection Of No Radical, Özlem Öter, Aki̇f Ci̇han Aydin, Merve Zeyrek Ongun, Erdal Çeli̇k

Turkish Journal of Chemistry

Nitric oxide is one of the most important biochemical parameters in biological processes; it is also known as carcinogenic. There is need for the design of stable and durable solid phase nitric oxide sensors. In this study, we immobilized the nitric oxide sensitive molecules pyrene, tris(2,2'-bipyrdyl)dichlororuthenium(II) hexahydrate (Ru(bipy)$_{3}^{2+})$, and magnesium phthalocyanine (Mg-Pc) for the first time in polymeric or glassy matrices. We applied silver nanoparticles and ionic liquids in the fabrication process of polymeric electrospun fibers and thin films. We compared their NO sensitivity in micelle solutions that mimic the cell medium by both steady state and lifetime-based fluorescence measurements. …


Synthesis, Molecular Docking, And Pharmacological Evaluation Of Halobenzodithiophene Derivatives Against Alpha-Glucosidase, Urease, And Free Radical Production, Ghulam Abbas, Zahid Hassan, Ahmed Al-Harrasi, Syed Aun Muhammad, Ahood Juma Al-Quraini1, Zahra Khamis Al-Maani1, Ahmed Mohammed Al-Adawai Jan 2018

Synthesis, Molecular Docking, And Pharmacological Evaluation Of Halobenzodithiophene Derivatives Against Alpha-Glucosidase, Urease, And Free Radical Production, Ghulam Abbas, Zahid Hassan, Ahmed Al-Harrasi, Syed Aun Muhammad, Ahood Juma Al-Quraini1, Zahra Khamis Al-Maani1, Ahmed Mohammed Al-Adawai

Turkish Journal of Chemistry

Benzodithiophenes are heterocyclic compounds that have various medicinal and industrial applications. In the present study, halobenzodithiophene, the simplest benzofused thiophene, and its derivatives were synthesized and evaluated against alpha-glucosidase, urease, and free radical production. In the alpha-glucosidase inhibition assay, compound 2,2-bisbenzothiophne (1) exhibited potent activity with IC$_{50}$ = 135 $\pm $ 0.51 $\mu $M, while its derivative 2,7-bis(butoxycarbonyl)-3,6-dichlorobenzo[1,2-$b$;6,5-$b$']dithiophene (2) exhibited promising inhibition with IC$_{50}$ = 263 $\pm $ 0.32 $\mu $M. In the 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical-scavenging assay, compound 2 exhibited promising activity with IC$_{50}$ = 33 $\pm $ 0.42 $\mu $M, while compound 1 showed moderate inhibition in the urease …


Differential Pulse Voltammetric Determination Of Dopamine Using Pd Nanoparticles Deposited On (3-Aminopropyl)Triethoxysilane Functionalized Ceo$_{2}$ Nanoparticles, Muhammet Güler Jan 2018

Differential Pulse Voltammetric Determination Of Dopamine Using Pd Nanoparticles Deposited On (3-Aminopropyl)Triethoxysilane Functionalized Ceo$_{2}$ Nanoparticles, Muhammet Güler

Turkish Journal of Chemistry

In this study, a novel and effective electrochemical sensor for determination of dopamine (DA) was successfully developed by the modification of a glassy carbon electrode (GCE) using Pd nanoparticles deposited on (3-aminopropyl)triethoxysilane functionalized nanoceria (Pd@CeO$_{2}$-APTES) and nafion used as a protective membrane. The synthesized nanocomposites were evaluated using X-ray diffraction, high-resolution transmission electron microscopy, and Fourier transform infrared spectroscopy. Moreover, the electrochemical properties of the modified electrodes were investigated using cyclic voltammetry, electrochemical impedance voltammetry, and differential pulse voltammetry (DPV). The Nf/Pd@CeO$_{2}$-APTES/GCE showed a linear range of 2.5--149.5 $\mu $M for DA by DPV with a notable sensitivity of 3.89 …


Use Of Calcined Layered Double Hydroxide [Zn$_{2}$-Al-Co$_{3}$] For Removal Of Textile Dye Acid Green 1 From Wastewater: Kinetic, Equilibrium, Comparative, And Recycling Studies, El Hassane Mourid, Mohamed Lakraimi, Souad El Abridi, Lhaj Benaziz, El Hassan Elkhattabi, Moha Berraho Jan 2018

Use Of Calcined Layered Double Hydroxide [Zn$_{2}$-Al-Co$_{3}$] For Removal Of Textile Dye Acid Green 1 From Wastewater: Kinetic, Equilibrium, Comparative, And Recycling Studies, El Hassane Mourid, Mohamed Lakraimi, Souad El Abridi, Lhaj Benaziz, El Hassan Elkhattabi, Moha Berraho

Turkish Journal of Chemistry

In the present study, calcined layered double hydroxides (CLDHs) were obtained by heating [Zn$_{2}$-Al-CO$_{3}$] at 500 $^{\circ}$C. The adsorption of the textile dye acid green 1 (AG1) by CLDH was carried out at different pH levels, adsorbent--adsorbate contact times, and AG1/CLDH mass ratios. Equilibrium at room temperature was reached after 24 h, which was confirmed by the kinetic modeling of the experimental data by the pseudo-second-order model. The adsorption is described by a Langmuir-type isotherm. The comparative study of adsorption isotherms in calcined and uncalcined phases reveals that the former could be a good candidate for trapping such pollutants. After …


Two-Area Load Frequency Control With Redox Ow Battery Using Intelligentalgorithms In A Restructured Scenario, Lakshmi Dhandapani, Fathima Peer, Ranganath Muthu Jan 2018

Two-Area Load Frequency Control With Redox Ow Battery Using Intelligentalgorithms In A Restructured Scenario, Lakshmi Dhandapani, Fathima Peer, Ranganath Muthu

Turkish Journal of Electrical Engineering and Computer Sciences

Load frequency control (LFC) is an essential aspect of power system dynamics. This paper focuses on the optimization of LFC for a two-area deregulated power system under different scenarios. A recent nature-inspired ower pollination algorithm (FPA), based on the pollination process of plants, is used to tune the proportional integral (PI) controller parameters of LFC for the global minima solution. FPA is compared with a genetic algorithm, particle swarm optimization, and a conventional PI controller. During large load disturbance in the areas, controllers are incapable of reducing frequency deviations and tie-line power oscillations due to the slow response of the …


An Elitist Approach For Solving The Traveling Salesman Problem Using An Animalmigration Optimization Algorithm, Ezgi̇ Ülker Jan 2018

An Elitist Approach For Solving The Traveling Salesman Problem Using An Animalmigration Optimization Algorithm, Ezgi̇ Ülker

Turkish Journal of Electrical Engineering and Computer Sciences

This paper presents an improved version of the animal migration optimization (AMO) algorithm for solving the traveling salesman problem (TSP), which is classified as a combinatorial NP-hard problem. AMO is one of the recent metaheuristic algorithms inspired by the migration behavior of animals and has been efficiently applied to a variety of optimization problems. The algorithm is improved by reconstructing the neighborhood topology of each animal during the migration. This modified algorithm is called the elitist animal migration optimization (ELAMO) algorithm, since elitism is introduced as a way in which the positions of the leaders are considered for the neighborhood …


A Novel Solution In The Simultaneous Deep Optimization Of Rgb-D Camera Calibration Parameters Using Metaheuristic Algorithms, Amir Safaei, Saeid Fazli Jan 2018

A Novel Solution In The Simultaneous Deep Optimization Of Rgb-D Camera Calibration Parameters Using Metaheuristic Algorithms, Amir Safaei, Saeid Fazli

Turkish Journal of Electrical Engineering and Computer Sciences

This article presents a novel method for estimating 19 parameters of RGB and depth camera calibration simultaneously. The proposed algorithm is based on applying metaheuristic methods for deep optimization and estimating all parameters of intrinsic, extrinsic, and lens distortions of cameras. This paper compares four metaheuristic algorithms, i.e. a genetic algorithm, particle swarm optimization, the colonial competitive algorithm, and the shuffled frog leaping algorithm, with a numerical algorithm called singular value decomposition. The proposed method does not need the initial estimation for optimization and it can avoid being trapped in local minima. By using nondirect estimation, we achieve middle computing …


Upper Envelope Detection Of Ecg Signals For Baseline Wander Correction: A Pilot Study, Mohammed Assam Ouali, Mouna Ghanai, Kheireddine Chafaa Jan 2018

Upper Envelope Detection Of Ecg Signals For Baseline Wander Correction: A Pilot Study, Mohammed Assam Ouali, Mouna Ghanai, Kheireddine Chafaa

Turkish Journal of Electrical Engineering and Computer Sciences

Baseline wander (BW) is a common low frequency artifact in electrocardiogram (ECG) signals. The prime cause from which BW arises is the patient's breathing and movement. To facilitate reliable visual interpretation of the ECG and to discern particular patterns in the ECG signal, BW needs to be removed. In this paper, a novel BW removal method is presented. The hypothesis is based on the observation that ECG signal variation covaries with its BW. As such, the P, Q, R, S, and T peaks will follow the baseline drift. On this basis, the following proposition is true: a reliable approximation of …


Circularly Polarized Implantable Antenna Characterization For Retinal Prosthesis Systems, Ademola Oluwaseun Kaka, Mehmet Toycan, Stuart Douglas Walker Jan 2018

Circularly Polarized Implantable Antenna Characterization For Retinal Prosthesis Systems, Ademola Oluwaseun Kaka, Mehmet Toycan, Stuart Douglas Walker

Turkish Journal of Electrical Engineering and Computer Sciences

We describe a miniaturized antenna design for retinal prosthesis applications that enhances data transfer between the implant and external camera. The circularly polarized and conformal 2.4--2.48 GHz microstrip patch antenna was simulated inside the vitreous humor and is intended for biomedical applications. Modified Hilbert and serpentine geometries were used for the proposed implant antenna design. Capacitive radiator loading offered miniaturized dimensions of 5.8 $\times $ 6.5 $\times $ 2 mm$^{3}$ (width $\times $ height $\times $ thickness mm$^{3})$. A truncated design enhanced the intrinsic circular polarization characteristics to $>$3 dB axial ratio. Polydimethylsiloxane substrate and superstrate materials were used …


Ab Initio Study Of The Structural, Electronic, And Magnetic Properties Of Co$_{2}$Fega And Co$_{2}$Fesi And Their Future Contribution To The Building Of Quantum Devices, Abdallah Oumsalem, Yamina Bourezig, Zakia Nabi, Badra Bouabdallah Jan 2018

Ab Initio Study Of The Structural, Electronic, And Magnetic Properties Of Co$_{2}$Fega And Co$_{2}$Fesi And Their Future Contribution To The Building Of Quantum Devices, Abdallah Oumsalem, Yamina Bourezig, Zakia Nabi, Badra Bouabdallah

Turkish Journal of Electrical Engineering and Computer Sciences

How small can an electronic device be and still function? How many atoms are needed for such device? At what point will the semiconductor fabrication technology be unable to construct anything smaller? These are common questions asked by researchers, and the answers indicate the short-term limitations on the use of semiconductor technology. When we reach these limitations, we can propose two methods to solve these problems: first, we could continue using semiconductor technology, alongside the development of new theories and techniques to counter quantum effects caused by the miniaturization of electronic devices like transistors and microprocessors. Second, we could exploit …


Gait Pattern Discrimination Of Als Patients Using Classification Methods, Süleyman Bi̇lgi̇n, Zahi̇de Eli̇f Akin Jan 2018

Gait Pattern Discrimination Of Als Patients Using Classification Methods, Süleyman Bi̇lgi̇n, Zahi̇de Eli̇f Akin

Turkish Journal of Electrical Engineering and Computer Sciences

Amyotrophic lateral sclerosis (ALS) is a mortal and idiopathic neurodegenerative disturbance of the human motor system. The disturbances of locomotion due to neurodegenerative diseases (NDDs) consisting of ALS, Parkinson disease (PD), and Huntington disease (HD) cause some abnormal fluctuations in gait signals. The investigation into gait patterns of NDDs provides significant information in order to develop new biomedical diagnosis devices. The main objective of this study is to evaluate the best discrimination method of ALS among control subjects (Co.), PD patients, and HD patients. The D2, D4, D5, and D6 detailed components, which were determined as critical features extracted from …


Bagged Tree Classification Of Arrhythmia Using Wavelets For Denoising, Compression, And Feature Extraction, Özgür Tomak, Temel Kayikçioğlu Jan 2018

Bagged Tree Classification Of Arrhythmia Using Wavelets For Denoising, Compression, And Feature Extraction, Özgür Tomak, Temel Kayikçioğlu

Turkish Journal of Electrical Engineering and Computer Sciences

Arrhythmia, also known as dysrhythmia, is a condition involving an irregular heartbeat. A problem in the heart may cause problems in other organs, and as time passes, this will lead to more severe problems. Arrhythmia must be detected at an early stage to prevent such a problem occurring in the heart. Detection of arrhythmia from an electrocardiogram is an easy method that does not need much equipment and does not harm the patient. The purpose of this research is to find a faster and more accurate system to classify nine classes of arrhythmia. The St. Petersburg Institute of Cardiological Technics …


Özyeğin Biopsy Robot: System Integration Architecture And Motion Compensation Of A Moving Target, Awais Ahmad, Özkan Bebek Jan 2018

Özyeğin Biopsy Robot: System Integration Architecture And Motion Compensation Of A Moving Target, Awais Ahmad, Özkan Bebek

Turkish Journal of Electrical Engineering and Computer Sciences

This paper presents the complete system architecture of a robotic biopsy system for real-time operations. The system has individual functional blocks working simultaneously including a 5 DoF parallel robot, ultrasound (US) imaging machine, two robotic manipulators, and a motion capturing system. Details of the real-time functionality of the robotic system components working with spatial and computational synchronization are presented. This paper also deals with a scenario in which the target tissue is moving due to the breathing of the patient. The motion of the needle tip and the target is tracked using US images as feedback. Two types of control …


An Efficient Recurrent Fuzzy Cmac Model Based On A Dynamic-Group--Based Hybrid Evolutionary Algorithm For Identification And Prediction Applications, Chin-Ling Lee, Chengjian Lin Jan 2018

An Efficient Recurrent Fuzzy Cmac Model Based On A Dynamic-Group--Based Hybrid Evolutionary Algorithm For Identification And Prediction Applications, Chin-Ling Lee, Chengjian Lin

Turkish Journal of Electrical Engineering and Computer Sciences

This article presents an efficient TSK-type recurrent fuzzy cerebellar model articulation controller (T-RFCMAC) model based on a dynamic-group--based hybrid evolutionary algorithm (DGHEA) for solving identification and prediction problems. The proposed T-RFCMAC model is based on the traditional CMAC model and the Takagi--Sugeno--Kang (TSK) parametric fuzzy inference system. Otherwise, the recurrent network, which imports feedback links with a receptive field cell, is embedded in the T-RFCMAC model, and the feedback units are used as memory elements. The DGHEA, which is a hybrid of the dynamic-group quantum particle swarm optimization (QPSO) and the Nelder--Mead method, is proposed for adjusting the parameters of …


A Noninvasive Time-Frequency-Based Approach To Estimate Cuffless Arterial Blood Pressure, Ömer Faruk Ertuğrul, Necmetti̇n Sezgi̇n Jan 2018

A Noninvasive Time-Frequency-Based Approach To Estimate Cuffless Arterial Blood Pressure, Ömer Faruk Ertuğrul, Necmetti̇n Sezgi̇n

Turkish Journal of Electrical Engineering and Computer Sciences

Arterial blood pressure (ABP) is one of the most vital signs in the prophylaxis and treatment of blood pressure-related diseases because raised blood pressure is the most significant cause of death and the second major cause of disability in the world. Higher ABP yields greater strain on arteries and these extra strains turn arteries into thicker, less flexible, and more narrow structures. This increases the possibility of having an artery busting or artery occlusion, which are the primary reasons for heart attacks, kidney disease, or strokes. In addition to its importance in monitoring cardiovascular homeostasis, measurement of ABP is imperative …


Neuron Modeling: Estimating The Parameters Of A Neuron Model From Neural Spiking Data, Reşat Özgür Doruk Jan 2018

Neuron Modeling: Estimating The Parameters Of A Neuron Model From Neural Spiking Data, Reşat Özgür Doruk

Turkish Journal of Electrical Engineering and Computer Sciences

We present a modeling study aiming at the estimation of the parameters of a single neuron model from neural spiking data. The model receives a stimulus as input and provides the firing rate of the neuron as output. The neural spiking data will be obtained from point process simulation. The resultant data will be used in parameter estimation based on the inhomogeneous Poisson maximum likelihood method. The model will be stimulated by various forms of stimuli, which are modeled by a Fourier series (FS), exponential functions, and radial basis functions (RBFs). Tabulated results presenting cases with different sample sizes (# …


Improving The Sensitivity And Accuracy Of Microcantilever Biosensors By A Truss Structure Within Air Medium, Soheyla Elmi, Zahra Elmi Jan 2018

Improving The Sensitivity And Accuracy Of Microcantilever Biosensors By A Truss Structure Within Air Medium, Soheyla Elmi, Zahra Elmi

Turkish Journal of Electrical Engineering and Computer Sciences

Early diagnosis is a very fundamental issue in treating most diseases and for this purpose microcantilevers are very effective and reliable devices. In this work, four models of biosensor-based microcantilever are compared and a novel design with high sensitivity, quality factor, and accuracy is proposed. A truss structure is designed near the anchored end of the microcantilever, which improves the sensitivity in order to increase detection accuracy. A linear relationship between resonance frequency shift and masses has been estimated for all the designs. High quality factor, which increases the accuracy of measurement, is taken into account as the other benefit …


Diode Clamped Gate Driver-Based High Voltage Pulse Generator For Electroporation, Krishnaveni Subramani, Rajini Veeraraghavalu Jan 2018

Diode Clamped Gate Driver-Based High Voltage Pulse Generator For Electroporation, Krishnaveni Subramani, Rajini Veeraraghavalu

Turkish Journal of Electrical Engineering and Computer Sciences

Pulsed electric field technology is an emerging nonthermal food processing method. PEF food processing requires a high voltage pulse generator that produces high intensive pulses to be delivered to the food product. Innovation in semiconductor technology motivates researchers to modernize high voltage pulse generators to reduce the cost, size, and complexities in circuit operation and to increase the suitability for food processing since the last few decades. The present study aims to explore a high voltage pulse generator for electroporation study. The implemented high voltage pulse generator develops $\sim $1.62 kV with adjustable pulse widths of 0.62 $\mu $s and …


Pattern Diversity Antenna For On-Body And Off-Body Wban Links, Sema Dumanli Jan 2018

Pattern Diversity Antenna For On-Body And Off-Body Wban Links, Sema Dumanli

Turkish Journal of Electrical Engineering and Computer Sciences

Maintaining the quality and the reliability of a wireless body area network (WBAN) has a variety of challenges, one of which is the design of the on-body antenna. The on-body antenna often forms both on-body and off-body links and needs to have an application-specific pattern to secure the connection. The antenna should direct its energy in parallel to the human skin while establishing an on-body link, ideally omnidirectionally, while an on-body link would benefit from a directional radiation pattern perpendicular to human skin. Moreover, the lossy body tissue is within the reactive region of the antenna affecting the antenna performance; …


Development Of Intelligent Decision Support System Using Fuzzy Cognitive Maps For Migratory Beekeepers, Ahmet Albayrak, Feci̇r Duran, Rai̇f Bayir Jan 2018

Development Of Intelligent Decision Support System Using Fuzzy Cognitive Maps For Migratory Beekeepers, Ahmet Albayrak, Feci̇r Duran, Rai̇f Bayir

Turkish Journal of Electrical Engineering and Computer Sciences

This study presents the development of an intelligent information system using fuzzy cognitive maps that provides information to migratory beekeepers about the nectar flow and climate conditions in the regions they will visit. Beekeeping is an agricultural activity essentially focused on honey production. High honey yields in beekeeping can be achieved through migratory beekeeping. Migratory beekeepers complete the honey production season by carrying their hives to regions with high nectar flow. Beekeepers decide on the regions they will visit based on their previous experiences. In this study, a software-based system that provides information to the beekeepers about the honey yield …


Performance Evaluation Of Alumina Trihydrate And Silica-Filled Silicone Rubber Composites For Outdoor High-Voltage Insulations, Hidayatullah Khan, Muhammad Amin, Ayaz Ahmad Jan 2018

Performance Evaluation Of Alumina Trihydrate And Silica-Filled Silicone Rubber Composites For Outdoor High-Voltage Insulations, Hidayatullah Khan, Muhammad Amin, Ayaz Ahmad

Turkish Journal of Electrical Engineering and Computer Sciences

In recent years, silicone rubber-based composites have been widely investigated for outdoor applications due to their promising insulating properties. However, mechanical, thermal, and tracking properties of pure silicone rubber are very poor, which restrains its application for long-term performance. In this research work, the influence of microsized alumina trihydrate (ATH) and micro/nanosized silica (SiO$_{2})$ fillers on mechanical, thermal, and electrical properties of room temperature vulcanized silicone rubber (RTV-SiR) has been studied. SiR-blends with varying amounts of ATH and SiO$_{2}$ particles were prepared by blending in a two-roll mixing mill, compression molding, and postcuring processes in sequence. In order to evaluate …


Comparative Analysis Of Mabc With Knn, Som, And Aco Algorithms For Ecg Heartbeat Classification, Seli̇m Di̇lmaç, Zümray Ölmez, Tamer Ölmez Jan 2018

Comparative Analysis Of Mabc With Knn, Som, And Aco Algorithms For Ecg Heartbeat Classification, Seli̇m Di̇lmaç, Zümray Ölmez, Tamer Ölmez

Turkish Journal of Electrical Engineering and Computer Sciences

In this paper, we proposed a classification method based on a nature-inspired algorithm, i.e., modified artificial bee colony (MABC). This method was applied to electrocardiogram (ECG) heartbeat classification. ECG data was obtained from MITBIH database. Eight different types of heartbeats (N, j, V, F, f, A, a, and R) were analyzed. For a better classification result, both time domain and frequency domain features were used. Feature selection was done by divergence analysis. MABC classification accuracy and heartbeat sensitivity values were compared with the results of other methods. Among other classifiers, k-nearest neighbor (KNN), Kohonen's self-organizing map (SOM), and ant colony …


Attenuating Saturated-Regulator Operation Effect Of Brushless Dc Motors Through Genetic-Based Fuzzy Logic Estimator, Emre Çeli̇k, Ni̇hat Öztürk Jan 2018

Attenuating Saturated-Regulator Operation Effect Of Brushless Dc Motors Through Genetic-Based Fuzzy Logic Estimator, Emre Çeli̇k, Ni̇hat Öztürk

Turkish Journal of Electrical Engineering and Computer Sciences

As brushless DC motor (BLDCM) speed approaches base speed, current regulators gradually saturate and lose their ability to perform their regulating task, which causes a dramatic fall in the phase currents and motor power. To control the current to a greater extent and avoid power decline, a new reference current generation technique based on a simple fuzzy logic estimator (FLE) is introduced in this paper. According to motor speed and current command, the developed FLE decides the proper commutation angle $\alpha $, which is the angle relative to normal commutation instant used for setting the current slew rate during commutation. …


Size Investigation Of Silicon Nanoclusters Deposited On Hopg Using Noncontact Atomic Force Microscopy, Mümi̇n Mehmet Koç Jan 2018

Size Investigation Of Silicon Nanoclusters Deposited On Hopg Using Noncontact Atomic Force Microscopy, Mümi̇n Mehmet Koç

Turkish Journal of Physics

The sizes of silicon nanoparticles produced using two different novel methods are investigated in this report. The method of production used to generate silicon oxide nanoparticles was achieved via gas aggregation codeposition with water on a cold target, and also via a liquid jet method. The nanoparticles were drop-cast on a highly oriented pyrolytic graphite (HOPG) substrate and assessed using ultrahigh vacuum atomic force microscopy (AFM). Noncontact constant force mode was used in the AFM investigations. The silicon nanoparticles produced using the gas aggregation and water codeposition method were found to be smaller than 2 nm. A degree of deviation …


Improvement Of Heart Attack Prediction By The Feature Selection Methods, Hi̇dayet Takci Jan 2018

Improvement Of Heart Attack Prediction By The Feature Selection Methods, Hi̇dayet Takci

Turkish Journal of Electrical Engineering and Computer Sciences

Prediction of a heart attack is very important since it is one of the leading causes of sudden death, especially in low-income countries. Although cardiologists use traditional clinical methods such as electrocardiography and blood tests for heart attack prediction, computer aided diagnosis systems that use machine learning methods are also in use for this task. In this study, we used machine learning and feature selection algorithms together. Our aim is to determine the best machine learning method and the best feature selection algorithm to predict heart attacks. For this purpose, many machine learning methods with optimum parameters and several feature …


Estimating Left Ventricular Volume With Roi-Based Convolutional Neural Network, Feng Zhu Jan 2018

Estimating Left Ventricular Volume With Roi-Based Convolutional Neural Network, Feng Zhu

Turkish Journal of Electrical Engineering and Computer Sciences

The volume of the human left ventricular (LV) chamber is an important indicator for diagnosing heart disease. Although LV volume can be measured manually with cardiac magnetic resonance imaging (MRI), the process is difficult and time-consuming for experienced cardiologists. This paper presents an end-to-end segmentation-free method that estimates LV volume from MRI images directly. The method initially uses Fourier transform and a regression filter to calculate the region of interest that contains the LV chambers. Then convolutional neural networks are trained to estimate the end-diastolic volume (EDV) and end-systolic volume (ESV). The resulting models accurately estimate the EDV and ESV …


A Strategy For Improving Netclust Server Placement For Multicloud Environments, Yuting Zhao, Jinhong Liu, Qing Fang, Lifang Xu, Changlai Du, Yuan Xiaoqun Jan 2018

A Strategy For Improving Netclust Server Placement For Multicloud Environments, Yuting Zhao, Jinhong Liu, Qing Fang, Lifang Xu, Changlai Du, Yuan Xiaoqun

Turkish Journal of Electrical Engineering and Computer Sciences

In this paper, we propose a fast server placement algorithm to improve the NetClust framework and make it more efficient and exible. To this end, we introduce hierarchical clustering technologies to the NetClust framework and propose a exible server placement algorithm, which integrates the agglomerative and divisive clustering technologies to reduce the time complexity and avoid the performance uctuation affected by the initial node selection. The experiment results show that our server placement algorithm may reduce the time complexity of server selection of NetClust significantly and improve the exibility and applicability of the NetClust.