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Corrosion And Wear Behaviour Of Highly Porous Ti-Tib-Tin$_{\Mathbf{X}}$ In Situ Composites In Simulated Physiological Solution, Fati̇h Toptan
Corrosion And Wear Behaviour Of Highly Porous Ti-Tib-Tin$_{\Mathbf{X}}$ In Situ Composites In Simulated Physiological Solution, Fati̇h Toptan
Turkish Journal of Chemistry
Highly porous Ti matrix composites can be a solution for some of the major clinical concerns for the load bearing implants such as low tribocorrosion resistance, stress shielding, and lack of biological anchorage. In order to respond to these needs, highly porous Ti-TiB-TiN$_{x}$ in-situ composites were synthesized by pressureless sintering using BN as reactant and urea as space holder. Corrosion behaviour was investigated at body temperature, in phosphate buffer saline solution (PBS), by measuring open circuit potential (OCP) and cyclic polarization. Wear behaviour was studied in PBS by reciprocating against a 10 mm diameter alumina ball under 3 N of …
A Review: A Comparison Of Different Adsorbents For Removal Of Cr (Vi), Cd (Ii) And Ni (Ii), Anja Pfeifer, Mojca Skerget
A Review: A Comparison Of Different Adsorbents For Removal Of Cr (Vi), Cd (Ii) And Ni (Ii), Anja Pfeifer, Mojca Skerget
Turkish Journal of Chemistry
A review of the studies dealing with the removal of chromium, cadmium, and nickel ions with different adsorbents published in the literature between 2014 and 2018 is given in tabular form, along with the adsorption conditions, adsorption isotherm, and kinetic models applied by the authors to model the experimental data and adsorption capacities. The review focuses on the efficiency of ion removal.
Photochromic And Fluorescence Properties Of Coumarin Fulgimides, Khamis Nassor Ally, Leyla Öztürk, Mahmut Köse
Photochromic And Fluorescence Properties Of Coumarin Fulgimides, Khamis Nassor Ally, Leyla Öztürk, Mahmut Köse
Turkish Journal of Chemistry
Four new fulgimides possessing a fluorescent coumarin unit were synthesized from the corresponding fulgides, and their photochromic as well as fluorescence properties were investigated. The open-ring forms of coumarin fulgimides were found to exhibit fluorescence in the visible region. Upon exposure to UV light, the fulgimides were transformed into the nonfluorescent closed-ring forms, which can be reverted to the initial fluorescent open-ring forms on exposure to visible light. The efficiency of quenching of fluorescence was as high as 95% at the photostationary state of UV irradiation.
Synthesis, Antioxidant And Antimicrobial Properties Of Novel Pyridyl-Carbonyl Thiazoles As Dendrodoine Analogs, Zafer Şahi̇n, Sevde Nur Bi̇lteki̇n, Leyla Yurttaş, Şeref Demi̇rayak
Synthesis, Antioxidant And Antimicrobial Properties Of Novel Pyridyl-Carbonyl Thiazoles As Dendrodoine Analogs, Zafer Şahi̇n, Sevde Nur Bi̇lteki̇n, Leyla Yurttaş, Şeref Demi̇rayak
Turkish Journal of Chemistry
Marine compound dendrodoine was first obtained from tunicate species (Dendrodo grossularia). It has a five-membered ring, namely, it is a heterocycle thiadiazole, which is found rarely in natural sources. Following its biological activities, novel analogs have been investigated recently. Synthesis of the analogs for this study is realized with uncommon thiazole closure, including methylene-carbonyl condensation. Structures are elucidated by NMR (1H, 13C) and HRMS spectrums. As an alkaloid derivative, antioxidant properties were evaluated with DPPH and FRAP assays and antimicrobial effect with microdilution method. Among the series, 3bc-3cf showed higher antioxidant activity than those having 3 or 4-pyridyl substituents. There …
Fabrication And Characterization Of Boric Acid-Crosslinked Ethyl Cellulose And Polyvinyl Alcohol Films As Potential Drug Release Systems For Topical Drug Delivery, Nasrin Aliasgharlou, Farzin Asghari Sana, Saba Khoshbakht, Pezhman Zolfaghari, Hamed Charkhian
Fabrication And Characterization Of Boric Acid-Crosslinked Ethyl Cellulose And Polyvinyl Alcohol Films As Potential Drug Release Systems For Topical Drug Delivery, Nasrin Aliasgharlou, Farzin Asghari Sana, Saba Khoshbakht, Pezhman Zolfaghari, Hamed Charkhian
Turkish Journal of Chemistry
In this study, boric acid (BA) is employed as a crosslinking agent to improve the characteristics of two commonly used polymeric films, ethyl cellulose (EC) and polyvinyl alcohol (PVA), for topical drug delivery applications. The developed films are characterized by FTIR spectroscopy and SEM analysis. The results show that the surfaces of the prepared films are even and transparent, except for the BA-modified EC sample. The initial cumulative release for erythromycin (EM) is found to be 0.30 and 0.36 mg/mL for EC and PVA films, which drops to 0.25 and 0.20 mg/mL after BA crosslinking, respectively, after 1 h at …
Preparation, Characterization, And Binding Profile Of Imprinted Semi-Ipn Cryogel Composite For Aluminum, Shahnila Shah, Huma Shaikh, Najma Memon, Muhammad Igbal Bhanger, Tahira Qureshi, Humaira Khan, Adi̇l Deni̇zli̇
Preparation, Characterization, And Binding Profile Of Imprinted Semi-Ipn Cryogel Composite For Aluminum, Shahnila Shah, Huma Shaikh, Najma Memon, Muhammad Igbal Bhanger, Tahira Qureshi, Humaira Khan, Adi̇l Deni̇zli̇
Turkish Journal of Chemistry
Human body is greatly exposed to aluminum due to its high abundance in the environment. This nonessential metal is a threat to the patients of chronic renal disorders, as it is easily retained in their plasma and quickly accumulates in different tissues. Thus, there is great need to remove it from the aqueous environment. In this study, Al$^{3+}$ imprinted semiinterpenetrating polymer network (semi-IPN)-based cryogel composite was prepared and applied for the purification of environmental and drinking water samples from aluminum. Poly (2-hydroxyethyl methacrylate) (pHEMA) discs were produced via cryogenic treatment and imprinted semi-IPN was introduced to the 3-(trimethoxysilyl) propyl acrylate-modified …
Chemical Composition, Antimicrobial, And Lipase Enzyme Activity Of Essential Oil And Solvent Extracts From Serapias Orientalis Subsp. Orientalis, İshak Eri̇k, Gözde Kiliç, Eli̇f Öztürk, Şengül Alpay Karaoğlu, Nuretti̇n Yayli
Chemical Composition, Antimicrobial, And Lipase Enzyme Activity Of Essential Oil And Solvent Extracts From Serapias Orientalis Subsp. Orientalis, İshak Eri̇k, Gözde Kiliç, Eli̇f Öztürk, Şengül Alpay Karaoğlu, Nuretti̇n Yayli
Turkish Journal of Chemistry
The volatile components of essential oil (EO), SPME, and SPME of solvent extracts (n-hexane, methanol, and water) obtained from fresh Serapias orientalis subsp. orientalis(Soo) were analyzed by GC-FID/MS. EO of Soo gave 11 compounds in the percentage of 99.97%; capronaldehyde (37.01%), 2-(E)-hexenal (23.19%), and n-nonanal (19.05%) were found to be major constituents. SPME GC-FID/MS analyses of fresh plant and solvent extracts of Soo revealed 7, 12, 7, and 4 compounds within the range of 99.7% to 99.9%. Limonene (76.5%, 41.7%, and 61.3%) was the major compound in SPMEs of the n-hexane and methanol extracts. α-Methoxy-p-cresol (52.9%) was the main component …
Plant Response To Salinity: An Analysis Of Ros Formation, Signaling, And Antioxidant Defense, Turgut Yi̇gi̇t Akyol, Oğuzhan Yilmaz, Bariş Uzi̇lday, Rengi̇n Özgür Uzi̇lday, İsmai̇l Türkan
Plant Response To Salinity: An Analysis Of Ros Formation, Signaling, And Antioxidant Defense, Turgut Yi̇gi̇t Akyol, Oğuzhan Yilmaz, Bariş Uzi̇lday, Rengi̇n Özgür Uzi̇lday, İsmai̇l Türkan
Turkish Journal of Botany
Reactive oxygen species (ROS) are byproducts of normal plant metabolism and their production is elevated under environmental stresses such as drought, extreme temperature, and salinity. Among these, salinity is a worldwide problem that impacts the fertility of arable lands and sustainability of food security, which is getting more attention due to climate change. Halophytes can survive and reproduce in soils containing high concentrations of salt and have developed adaptation mechanisms at physiological, biochemical, and molecular levels including maintenance of ROS metabolism. In this review, we aim to summarize findings related to ROS production, signaling, scavenging, and especially ROS avoidance mechanisms …
Botanical Characteristics, Potential Uses, And Cultivation Possibilities Of Mustards In Turkey: A Review, Fatma Kayaçeti̇n
Botanical Characteristics, Potential Uses, And Cultivation Possibilities Of Mustards In Turkey: A Review, Fatma Kayaçeti̇n
Turkish Journal of Botany
The mustard species [(Brassica juncea (brown mustard),B. nigra (black mustard),B. rapa syn. B. campestris (field mustard or turnip), and Sinapis alba (white mustard or yellow mustard)] constitute important genetic resources and sources of raw materials to large number of agrobased industries in Turkey and elsewhere. S. alba is usually used as a condiment in dry form. B. nigra is used as a condiment and as vegetable with dietary fibre, vitamin C, and other anticancer compounds. B. juncea is used for oil and as spice. B. rapa is popularly used for biofuel raw material. However, there is poor focus on their …
Biochemical And Morphological Responses To Cadmium-Induced Oxidative Stress In Cladophora Glomerata, Abuzer Çelekli̇, Hi̇lal Bulut
Biochemical And Morphological Responses To Cadmium-Induced Oxidative Stress In Cladophora Glomerata, Abuzer Çelekli̇, Hi̇lal Bulut
Turkish Journal of Botany
This study aimed to assess the effect of cadmium (Cd2+) concentrations on biovolume, pigments, malondialdehyde (MDA), hydrogen peroxide, proline, total phenolic compounds, total protein, and total carbohydrate contents of Cladophora glomerata . Cultivations of the alga (8.0 ± 0.1 g as fresh weight) were exposed to 7.5, 15, 30, and 60 mg/L of Cd2+ ions in 500 mL flasks containing 400 mL of the medium on a shaker at 120 rpm for 7 days. Results of Fourier transform infrared analyses indicated that the amide, anionic, and amino groups had significant rolesin the binding of Cd2+ on C. glomerata. The detrimental …
Karyotypic Phylogeny And Polyploidy Variations Of Paronychia (Caryophyllaceae) Taxa In Turkey, Hali̇l Erhan Eroğlu, Derya Altay, Ümi̇t Budak, Esra Marti̇n
Karyotypic Phylogeny And Polyploidy Variations Of Paronychia (Caryophyllaceae) Taxa In Turkey, Hali̇l Erhan Eroğlu, Derya Altay, Ümi̇t Budak, Esra Marti̇n
Turkish Journal of Botany
Chromosomal data can provide very valuable information about karyotypic phylogeny and speciation. This is the first study on karyotype phylogeny and polyploidy variations of the genus Paronychia. In this context, the results are these: (1) in 14 taxa, the first report on chromosomes numbers; (2) in 2 taxa, equal chromosome numbers as in the previous report; (3) in all taxa, the first report of detailed karyotype analyses; (4) karyotype asymmetry data and generally symmetrical karyotypes; (5) karyotypic variations by mechanisms of dysploidy and polyploidy; and (6) phylogenetic relationships in Paronychia. The data indicate that Anatolia is an important area for …
An Integrated Approach To The Study Of Hypericum Occurring In Sicily, Antonio Giovino, Alessandra Carrubba, Silvia Lazzara, Edoardo Napoli, Gianniantonio Domina
An Integrated Approach To The Study Of Hypericum Occurring In Sicily, Antonio Giovino, Alessandra Carrubba, Silvia Lazzara, Edoardo Napoli, Gianniantonio Domina
Turkish Journal of Botany
An integrated approach to the study of taxa of the genus Hypericum occurring in Sicily is proposed. The results of morphological, biochemical, and molecular analyses are combined to better assess the relationships between the species investigated and test the suitability of DNA barcoding technique in the discrimination of these taxa. For the name Hypericum aegypticum subsp. webbii (Spach) N. Robson a lectotype is designated. For Hypericum triquetrifolium Turra a lectotype and a supporting epitype are designated. The presence of Hypericum perforatum L. subsp. perforatum is excluded from Sicily and the previous reports have to be referred to H. perforatum subsp. …
An Attempt To Solve The Taxonomic Confusion Of Thlaspiceras F.K.Mey. Complex (Noccaea Moench-Brassicaceae) With Issrs, Kurtuluş Özgi̇şi̇, Ati̇la Ocak, Burcu Tarikahya Hacioğlu
An Attempt To Solve The Taxonomic Confusion Of Thlaspiceras F.K.Mey. Complex (Noccaea Moench-Brassicaceae) With Issrs, Kurtuluş Özgi̇şi̇, Ati̇la Ocak, Burcu Tarikahya Hacioğlu
Turkish Journal of Botany
Meyer separated Thlaspi into 12 genera, specifically using the seed-coat anatomy. Currently, only 4 species have been retained in Thlaspi s.str and all of the other species were divided into other genera, one of which was Thlaspiceras F.K.Mey.. Based on recent molecular studies and morphological features, Al-Shehbaz (2014) suggested recognizing all of Meyer?s segregates under Noccaea and Thlaspi s.str. All of Meyer?s Thlaspiceras species, namely Th. dolichocarpum (Zohary) F.K.Mey.,Th. eigii (Zohary) F.K.Mey., Th. crassifolium A.Huber-Morath andF.K.Mey., Th. bovis F.K.Mey., Th. oxyceras (Boiss.) F.K.Mey., Th. capricornutum F.K.Mey., Th. hubermorathii F.K.Mey., Th. cappadocicum (Boiss. and Balansa) F.K.Mey., Th. triangulare F.K.Mey., Th. rechingeri …
The Fluctuations Of Airborne Fungal Components In Western Romania, Nicoleta Ianovici
The Fluctuations Of Airborne Fungal Components In Western Romania, Nicoleta Ianovici
Turkish Journal of Botany
Outdoor regional concentrations of airborne fungal spores and fungal fragments were measured using the 7-day Lanzoni sampler. The daily and intradiurnal fluctuations recorded during the monitored period have been studied. The multiple regression analysis was performed in order to determine how much of the total variance in these concentrations could be explained by meteorological parameters. Daytime periodicity (statistically significant) was established only in a few cases. As the relative importance of the weather factors varied, they could not be ranked according to their effect.
Identification And Expressional Profiling Of Putative Max1 Gene In Sugar Beet (Beta Vulgaris L.), Ercan Selçuk Ünlü, Songül Gürel, Fatemeh Aflaki, Arman Pazuki, Günce Şahi̇n, Ekrem Gürel
Identification And Expressional Profiling Of Putative Max1 Gene In Sugar Beet (Beta Vulgaris L.), Ercan Selçuk Ünlü, Songül Gürel, Fatemeh Aflaki, Arman Pazuki, Günce Şahi̇n, Ekrem Gürel
Turkish Journal of Botany
Sugar beet is an industrial crop cultivated mostly for sucrose production. Today, modern hybridization applications have raised the sugar content to 20%. Considering the increased demand globally, it is required to develop new yield?increasing application strategies. This requires extensive knowledge of the genetic mechanisms to control plant growth and metabolism. Investigation of phytohormones is promising to increase our knowledge of plant growth and developmental processes. Strigolactones are recently introduced plant hormones. They are responsible for shoot and root architecture, and involved in development, communication, germination, and responses to stress. Four major proteins (AtD27, MAX1, MAX3, MAX4) are responsible for the …
Ultrastructural Response Of Wheat (Triticum Aestivum L.) Lines To Potential Allelopathy Of Alstonia Scholaris (L.) R. Br. Leaf Extract, Mansoor Hameed, Sana Fatima, Syed Mohsan Raza Shah, Farooq Ahmad, Muhammad Ashraf, Maryam Ghulam-Nabi, Muhammad Sajid Aqeel Ahmad, Iftikhar Ahmad, Ummar Iqbal
Ultrastructural Response Of Wheat (Triticum Aestivum L.) Lines To Potential Allelopathy Of Alstonia Scholaris (L.) R. Br. Leaf Extract, Mansoor Hameed, Sana Fatima, Syed Mohsan Raza Shah, Farooq Ahmad, Muhammad Ashraf, Maryam Ghulam-Nabi, Muhammad Sajid Aqeel Ahmad, Iftikhar Ahmad, Ummar Iqbal
Turkish Journal of Botany
An investigation was carried out to evaluate the impact of the allelopathic effect of Alstonia scholaris leaf extract on morphoanatomical and physiological characteristics of 5 wheat lines. Three extract dilutions were prepared, viz. 0 (control), 15 and 30% of the aqueous extract and sprayed on wheat lines (3094, 5066, M5082, 7076 and A2011) at 15-day intervals until maturity from November 2017 to May 2018. All wheat lines responded differently to an allelochemical extract of A. scholaris. Disintegration of root parenchyma and transformation of stem chlorenchyma to sclerenchyma in stems were noted in Line 3094. Increased sclerification in the root cortex …
Seed Morphology And Testa Ultrastructure In Allium Stipitatum Complex (Amaryllidaceae; Allioideae) And Their Systematic Significance, Mina Khorasani, Shahryar Saeidi Mehrvarz, Shahin Zarre
Seed Morphology And Testa Ultrastructure In Allium Stipitatum Complex (Amaryllidaceae; Allioideae) And Their Systematic Significance, Mina Khorasani, Shahryar Saeidi Mehrvarz, Shahin Zarre
Turkish Journal of Botany
Characteristic features of seed and testa cells in 13 species of Allium, representing its five recognized sections, Compactoprason, Megaloprason, Procerallium, Decipientia and Pseudoprason were studied using both stereomicroscope and scanning electron microscope. The identified characters, such as seed shape, alignment and shape of testa cells, features of outer cell walls, verruca type, density of verrucae and granules, seed size as well as cell wall undulations were evaluated statistically. The our findings indicated the significance level of P ? 0.01 for examined characters using the Kruskal-Wallis and ANOVA analyses.Two principal components of factor analysis revealed the following traits to be most …
Midkine Level May Be Used As A Noninvasive Biomarker In Crohn's Disease, Murat Keki̇lli̇, Alpaslan Tanoğlu, Fati̇h Karaahmet, Zeynal Doğan, Murat Can, Abdurrahi̇m Sayilir, Başak Çakal, Tolga Düzenli̇, Yavuz Beyazi̇t
Midkine Level May Be Used As A Noninvasive Biomarker In Crohn's Disease, Murat Keki̇lli̇, Alpaslan Tanoğlu, Fati̇h Karaahmet, Zeynal Doğan, Murat Can, Abdurrahi̇m Sayilir, Başak Çakal, Tolga Düzenli̇, Yavuz Beyazi̇t
Turkish Journal of Medical Sciences
Background/aim: Crohn's disease (CD) is a kind of inflammatory bowel disease. Midkine (MDK) is an endogenous inflammatory marker. We aimed to investigate the relationship between MDK levels and inflammation and hence determine whether MDK can be used as a noninvasive biomarker in active CD. Materials and methods: Sixty-five consecutive patients over the age of 18 with CD and 36 healthy controls were included in this study. CD patients' venous blood samples were taken before treatment. Serum MDK levels were determined in human plasma samples by enzyme-linked immunosorbent assay (ELISA) method. Results: The mean age of the study patients was 44.8 …
Correlation Of Serum Fatty Acid Binding Protein-4 And Interleukin-6 With Airflowlimitation And Quality Of Life In Stable And Acute Exacerbation Of Copd, Mohammad Reza Aslani, Zeynab Ghazaei, Hassan Ghobadi
Correlation Of Serum Fatty Acid Binding Protein-4 And Interleukin-6 With Airflowlimitation And Quality Of Life In Stable And Acute Exacerbation Of Copd, Mohammad Reza Aslani, Zeynab Ghazaei, Hassan Ghobadi
Turkish Journal of Medical Sciences
Background/aim: The serum fatty acid binding protein 4 (FABP-4) level increases in chronic inflammatory diseases. The present study aimed to examine serum FABP-4 and interleukin (IL)-6 levels in patients with stable and acute exacerbation of chronic obstructive pulmonary disease (COPD) and the correlation of these markers with airflow limitation. Materials and methods: We measured serum FABP-4 and IL-6 levels in 60 COPD patients [30 stable COPD (SCOPD), and 30 acute exacerbation of COPD (AECOPD)], and 30 healthy subjects and compared them with airflow limitation according to the COPD stage in the Global Initiative for Chronic Obstructive Pulmonary Disease (GOLD) criteria, …
Effect Of Metformin And Detorsion Treatment On Serum Anti-Müllerian Hormonelevels And Ovarian Histopathology In A Rat Ovarian Torsion Model, Sema Karakaş, Ci̇han Kaya, Hakan Güraslan, Damlanur Sakiz, Sema Süzen Çaypinar, Hüseyi̇n Cengi̇z, Murat Eki̇n, Levent Yaşar
Effect Of Metformin And Detorsion Treatment On Serum Anti-Müllerian Hormonelevels And Ovarian Histopathology In A Rat Ovarian Torsion Model, Sema Karakaş, Ci̇han Kaya, Hakan Güraslan, Damlanur Sakiz, Sema Süzen Çaypinar, Hüseyi̇n Cengi̇z, Murat Eki̇n, Levent Yaşar
Turkish Journal of Medical Sciences
Background/aim: Adnexal torsion is a common gynaecological emergency, and considered to be a problem mostly in reproductive-age women. To evaluate the effect of metformin and detorsion treatment on reducing ovarian reserve in an ovarian torsion model. Materials and methods: Twenty-four nonpregnant, Wistar Hannover rats were included in the study. Animals were divided into 3 groups: the control group, the detorsion only group, and the metformin + detorsion group. The first group received only laparotomy. In the second group, ovaries were fixed to the abdominal wall after performing 360° ovarian torsion, followed by detorsion after a 3-h period of ischemia. The …
The Effect Of Vitamin D Status On Different Neuromuscular Blocker Agents Reverse Time, İlknur Sui̇di̇ye Yorulmaz, Yavuz Demi̇raran, Onur Özlü, Burhan Dost
The Effect Of Vitamin D Status On Different Neuromuscular Blocker Agents Reverse Time, İlknur Sui̇di̇ye Yorulmaz, Yavuz Demi̇raran, Onur Özlü, Burhan Dost
Turkish Journal of Medical Sciences
Background/aim: This study is aimed to investigate the effects of vitamin D levels on sugammadex and neostigmine reversal times. Material and methods: Eighty patients between the ages of 18 and 65 years, with ASA I-III status who were undergoing surgery under general anesthesia were included in the study. A double blind fashion was used to randomly divide all the patients into two groups. At the end of the operation, sugammadex 2 mg/kg was administered to one group (Group sugammadex) and atropine and neostigmine was administered to the other group (Group neostigmine) intravenously. In the data analysis stage, the group was …
Horse Allergen Sensitivity And Respiratory Symptoms Among Horse Farm Workers, Burcu Baran Ketenci̇oğlu, İnsu Yilmaz, Nuri̇ Tutar, İnci̇ Gülmez, Fatma Sema Oymak
Horse Allergen Sensitivity And Respiratory Symptoms Among Horse Farm Workers, Burcu Baran Ketenci̇oğlu, İnsu Yilmaz, Nuri̇ Tutar, İnci̇ Gülmez, Fatma Sema Oymak
Turkish Journal of Medical Sciences
Background/aim: Sensitivity and symptoms related to animal proteins have been investigated in various occupational groups. However, data from horse farm workers are limited. We aimed to determine horse allergen sensitivity in the horse farm workers, and to evaluate its relationship with respiratory symptoms and functional parameters. Materials and methods: A total of 110 subjects were enrolled in the study. The study group consisted of 80 horse farm workers. Face-to-face surveys, skin prick tests (SPT), and pulmonary function tests (PFT) were performed in the study group. Control group consisted of 30 healthy subjects. SPT and PFTs were also performed for control …
Neurotrophic Factors In Bipolar Disorders Patients With Manic Episode, Özgür Korhan Tunçel, Gökhan Sarisoy, Eda Çeti̇n, Ebru Kaynar Tunçel, Bi̇rşen Bi̇lgi̇ci̇, Arzu Karaustaoğlu
Neurotrophic Factors In Bipolar Disorders Patients With Manic Episode, Özgür Korhan Tunçel, Gökhan Sarisoy, Eda Çeti̇n, Ebru Kaynar Tunçel, Bi̇rşen Bi̇lgi̇ci̇, Arzu Karaustaoğlu
Turkish Journal of Medical Sciences
Background/aim: Neurotrophins are one of the most important molecule groups affecting cerebral neuroplasticity. The amount of evidence about the role of changes in neuroplasticity in the pathophysiology of bipolar disease is growing. Materials and methods: We measured serum levels of brain-derived neurotrophic factor (BDNF), nerve growth factor (NGF), neurotrophin-3 (NT-3), glial cell-line derived neurotrophic factor (GDNF), vascular endothelial growth factor (VEGF), insulin-like growth factor-1 (IGF-1), fibroblast growth factor (FGF)-2, neuritin 1 (Nrn 1) in bipolar 1 manic episode patients (n = 45) and healthy control group. Results: When controlled for age, BMI and cortisol, it was found that the serum …
Prospective Evaluation Of Vascular Changes In Acute Respiratory Infections In Children With Cystic Fibrosis, Gökçen Kartal Öztürk, Aykut Eşki̇, Fi̇gen Çelebi̇ Çeli̇k, Seçi̇l Conkar, Fi̇gen Gülen, Esen Demi̇r, Ahmet Keski̇noğlu
Prospective Evaluation Of Vascular Changes In Acute Respiratory Infections In Children With Cystic Fibrosis, Gökçen Kartal Öztürk, Aykut Eşki̇, Fi̇gen Çelebi̇ Çeli̇k, Seçi̇l Conkar, Fi̇gen Gülen, Esen Demi̇r, Ahmet Keski̇noğlu
Turkish Journal of Medical Sciences
Background/aim: Acute exacerbations and chronic inflammation are risk factors for cardiovascular disease (CVD) in cystic fibrosis (CF) patients. The aim of this study was to investigate the effects of acute exacerbation therapy on arterial stiffness in children with CF. Materials and methods: Augmentation index (Aix) and pulse wave velocity (PWV) were measured before and after treatment and 1 month after the end of treatment in patients with acute exacerbation. The relationship between hemodynamic measurements and c-reactive protein (CRP) and pulmonary function tests (PFTs) was investigated. Results: Measurements before and after treatment were evaluated in 27 patients and were repeated in …
Dti-Mri Findings In Synthetic Cannabinoid Users, Fatma Di̇lek Gökharman, Sonay Aydin, Sali̇h Ci̇hat Paltun, Erdem Fati̇hoğlu, Şafak Yalçin Şahi̇ner, Pinar Nerci̇s Koşar
Dti-Mri Findings In Synthetic Cannabinoid Users, Fatma Di̇lek Gökharman, Sonay Aydin, Sali̇h Ci̇hat Paltun, Erdem Fati̇hoğlu, Şafak Yalçin Şahi̇ner, Pinar Nerci̇s Koşar
Turkish Journal of Medical Sciences
Background/aim: Synthetic cannabinoids (SCs) are full agonists of both cannabinoid receptors. Conventional magnetic resonance imaging (MRI) findings of SC users are mainly defined as diffusion restriction and T2/FLAIR hyperintensity. Diffusion tensor imaging (DTI) studies examining SC users have shown contradictory results. The aim of this study was to define white matter (WM) changes of SC users using DTI. Materials and methods: The study included 22 patients with a history of using SC for 5-37 months, and 22 healthy, age and sex- matched control subjects. A total of 41 diffusion gradient directions were used in the acquisition of diffusion imaging data. …
Roles Of Glycoprotein Glycosylation In The Pathogenesis Of An Endemic Osteoarthritis, Kashin-Beck Disease, And Effectiveness Evaluation Of Sodium Hyaluronate Treatment, Sen Wang, Zongqiang Gao, Huan Liu, Peilin Meng, Cuiyan Wu, Mikko Lammi, Xiong Guo
Roles Of Glycoprotein Glycosylation In The Pathogenesis Of An Endemic Osteoarthritis, Kashin-Beck Disease, And Effectiveness Evaluation Of Sodium Hyaluronate Treatment, Sen Wang, Zongqiang Gao, Huan Liu, Peilin Meng, Cuiyan Wu, Mikko Lammi, Xiong Guo
Turkish Journal of Medical Sciences
Background/aim: We aimed to explore the roles of glycoprotein glycosylation in the pathogenesis of Kashin-Beck disease (KBD), and evaluated the effectiveness of sodium hyaluronate treatment. Materials and methods: Blood and saliva were collected from KBD patients before and after the injection of sodium hyaluronate. Normal healthy subjects were included as controls. Saliva and serum lectin microarrays and saliva and serum microarray verifications were used to screen and confirm the differences in lectin levels among the three groups. Results: In saliva lectin microarray, bindings to Sophora japonica agglutinin (SJA), Griffonia (Bandeiraea) simplicifolia lectin I (GSL-I), Euonymus europaeus lectin (EEL), Maackia amurensis …
Investigation The Potential Use Of Silver Nanoparticles Synthesized By Propolis Extract As N-Acyl-Homoserine Lactone-Mediated Quorum Sensing Systems Inhibitor, Sedef İlk, Gamze Tan, Ezgi̇ Emül, Necdet Sağlam
Investigation The Potential Use Of Silver Nanoparticles Synthesized By Propolis Extract As N-Acyl-Homoserine Lactone-Mediated Quorum Sensing Systems Inhibitor, Sedef İlk, Gamze Tan, Ezgi̇ Emül, Necdet Sağlam
Turkish Journal of Medical Sciences
Background/aim: Quorum sensing (QS) is a chemical communication process that bacteria use to regulate virulence. Inhibition of QS (antiQS) overcomes the pathogenicity of bacteria. Silver nanoparticles (AgNPs) have been used as antimicrobials against pathogens, but have not been used against QS-mediated bacterial infection. Also, studies have been carried out on the inhibitory effects of propolis based structures on pathogen growth, but no studies have been found on their potential use as QS inhibitor. The present study aims to investigate the synthesis and characterization of silver nanoparticles (AgNPs) reduced with propolis extract (P-AgNPs) and evaluation of their antimicrobial and, for the …
Baicalein Nanofiber Scaffold Containing Hyaluronic Acid And Polyvinyl Alcohol: Preparation And Evaluation, Kamel Bachimam, Ezgi̇ Emül, Necdet Sağlam, Feza Korkusuz
Baicalein Nanofiber Scaffold Containing Hyaluronic Acid And Polyvinyl Alcohol: Preparation And Evaluation, Kamel Bachimam, Ezgi̇ Emül, Necdet Sağlam, Feza Korkusuz
Turkish Journal of Medical Sciences
Background/aim: Bone tumor is one of the major causes of tissue bone loss, particularly after performing surgical excision operation to bone lesion that needs to be replaced by biomaterials and ensure a complete filling of tissue-loss spaces. The purpose of our study was to produce a nanofiber-based bone graft scaffold to fill the gaps resulted from bone cancer treatment and also capable of carrying functional molecules that can play a major role in preventing further cancer growth at the targeted bone tissue. Materials and methods: Electrospinning method was used in order to produce nanofibers from different kinds of polymers; Hyaluronic …